[1] BRAY F, FERLAY J, SOERJOMATARAM I, et al. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries[J]. CA Cancer J Clin, 2018, 68(6): 394. doi: 10.3322/caac.21492
[2] BHAGAT A, KLEINERMAN ES. Anthracycline-induced cardiotoxicity: causes, mechanisms, and prevention[J]. Adv Exp Med Biol, 2020, 1257: 181.
[3] LI Y, YE Y, CHEN H. Astragaloside Ⅳ inhibits cell migration and viability of hepatocellular carcinoma cells via suppressing long noncoding RNA ATB[J]. Biomed Pharmacother, 2018, 99: 134. doi: 10.1016/j.biopha.2017.12.108
[4] DONG Z, ZHAO P, XU M, et al. Astragaloside Ⅳ alleviates heart failure via activating PPARα to switch glycolysis to fatty acid β-oxidation[J]. Sci Rep, 2017, 7(1): 2691. doi: 10.1038/s41598-017-02360-5
[5] GUI J, CHEN R, XU W, et al. Remission of CVB3-induced myocarditis with Astragaloside Ⅳ treatment requires A20(TNFAIP3) up-regulation[J]. J Cell Mol Med, 2015, 19(4): 850. doi: 10.1111/jcmm.12459
[6] DEBERGE M, YEAP XY, DEHN S, et al. MerTK cleavage on resident cardiac macrophages compromises repair after myocardial ischemia reperfusion injury[J]. Circ Res, 2017, 121(8): 930. doi: 10.1161/CIRCRESAHA.117.311327
[7] HU C, ZHANG X, WEI W, et al. Matrine attenuates oxidative stress and cardiomyocyte apoptosis in doxorubicin-induced cardiotoxicity via maintaining AMPKα/UCP2 pathway[J]. Acta Pharm Sin B, 2019, 9(4): 690. doi: 10.1016/j.apsb.2019.03.003
[8] TOMLINSON L, LU ZQ, BENTLEY RA, et al. Attenuation of doxorubicin-induced cardiotoxicity in a human in vitro cardiac model by the induction of the NRF-2 pathway[J]. Biomed Pharmacother, 2019, 112: 108637. doi: 10.1016/j.biopha.2019.108637
[9] LIN J, FANG L, LI H, et al. Astragaloside Ⅳ alleviates doxorubicin induced cardiomyopathy by inhibiting NADPH oxidase derived oxidative stress[J]. Eur J Pharmacol, 2019, 859: 172490. doi: 10.1016/j.ejphar.2019.172490
[10] THORP E, VAISAR T, SUBRAMANIAN M, et al. Shedding of the Mer tyrosine kinase receptor is mediated by ADAM17 protein through a pathway involving reactive oxygen species, protein kinase Cδ, and p38 mitogen-activated protein kinase (MAPK)[J]. J Biol Chem, 2011, 286(38): 33335. doi: 10.1074/jbc.M111.263020
[11] JIA Y, ZUO D, LI Z, et al. Astragaloside Ⅳ inhibits doxorubicin-induced cardiomyocyte apoptosis mediated by mitochondrial apoptotic pathway via activating the PI3K/Akt pathway[J]. Chem Pharm Bull (Tokyo), 2014, 62(1): 45. doi: 10.1248/cpb.c13-00556
[12] UEHARA H, SHACTER E. Auto-oxidation and oligomerization of protein S on the apoptotic cell surface is required for Mer tyrosine kinase-mediated phagocytosis of apoptotic cells[J]. J Immunol, 2008, 180(4): 2522. doi: 10.4049/jimmunol.180.4.2522
[13] ANWAR A, KEATING AK, JOUNG D, et al. Mer tyrosine kinase (MerTK) promotes macrophage survival following exposure to oxidative stress[J]. J Leukoc Biol, 2009, 86(1): 73. doi: 10.1189/jlb.0608334
[14] CAI B, THORP EB, DORAN AC, et al. MerTK cleavage limits proresolving mediator biosynthesis and exacerbates tissue inflammation[J]. Proc Natl Acad Sci USA, 2016, 113(23): 6526. doi: 10.1073/pnas.1524292113