CD137表达与慢性乙型肝炎患者肝脏免疫病理损伤程度的相关性研究

王博; 吴俊英; 徐超; 王博; 吴俊英; 徐超

doi:10.13898/j.cnki.issn.1000-2200.2016.09.002

[1]

European Association for the Study of the Liver.EASL clinical practice guidelines:management of chronic hepatitis B virus infection[J].J Hepatol,2012,57(1):167.

[2]

中华医学会肝病学分会,中华医学会感染病学分会.慢性乙型肝炎防治指南2010年更新版[J/CD].中华实验和临床感染病杂志(电子版),2011,5(1):79.

[3]

ZHANG Z,ZHANG JY,WANG LF,et al.Immunopathogenesis and prognostic immune markers of chronic hepatitis B virus infection[J].J Gastroenterol Hepatol,2012,27(2):223.

[4]

GANEM D,PRINCE AM.Hepatitis B virus infection-natural history and clinical consequences[J].N Engl J Med,2004,350(11):1118.

[5]

BEI Z,MAO PH,GUO QY,et al.Effects of costimulation on intrahepatic immunopathogenesis in patients with chronic HBV infection[J].Inflamm Res,2014,63(3):217.

[6]

KHAIROVA RA,MACHADO VR,DU J,et al.A potential role for pro-inflammatory cytokines inregulating synaptic plasticity in major depressive disorder[J].Int J Neuropsychopharmacol,2009,12(4):561.

[7]

涂远航,荣梅生,马勇.乙型肝炎患者肝组织中乙型肝炎病毒抗原与CD8⁺CD28⁺T细胞表达的关系及其临床意义[J].蚌埠医学院学报,2011,36(12):1373.

[8]

中华医学会传染病与寄生虫分会,肝病分会.病毒性肝炎治疗方案[J].中华传染病杂志,2001,19(1):56.

[9]

LAURA JP,UPKAR SG,ALBERTO Q,et al.Metabolic regulation of hepatitis B immunopathology by myeloid-derived suppressor cells[J].Nat Med,2015,21(6):591.

[10]

SHAO Z,HARFUDDIN Z,PANG WL,et al.Trogocytic CD137 transfer causes an internalization of CD137 ligand on murine APCs leading to reduced T cell costimulation[J].J Leukoc Biol,2015,pii:jlb.3A0213.

[11]

WANG J,ZHAO WX,CHENG L,et al.CD137-Mediated pathogenesis from chronic hepatitis to hepatocellular carcinoma in hepatitis B virus-transgenic mice[J].J Immunol,2010,185(12):7654.

[12]

SANMAMED MF,PASTOR F,RODRIGUEZ A,et al.Agonists of co-stimulation in cancer immunotherapy directed against CD137,OX40,GITR,CD27,CD28 and ICOS[J].Semin Oncol,2015,42(4):640.

[13]

INGRID E,DUMITRIU PB,CAROLINE JF,et al.high levels of costimulatory receptors OX40 and 4-1BB characterize CD4+CD28null T cells in patients with acute coronary syndrome[J].Circ Res,2012,110(6):857.

[14]

TESCHNER D,WENZEL G,DISTLER E,et al.In vitro stimulation and expansion of human tumour-reactive CD8+ cytotoxic T lymphocytes by anti-CD3 CD28 CD137 magnetic beads[J].J Immunol,2011,74(2):155.

[15]

高元元,吴俊英,李柏青,等.4-1BBL/4-1BB信号对系统性红斑狼疮患者外周血淋巴细胞活化的影响[J].蚌埠医学院学报,2011,36(11):1177.

[16]

王芳,吴俊英,吴正中,等.Pristane诱导狼疮模型鼠共刺激分子的表达变化[J].现代免疫学,2014,34(4):324.