[1] 厉有名.酒精性肝病的流行病学特点[J].实用肝脏病杂志, 2012, 15(3):180. doi: 10.3969/j.issn.1672-5069.2012.03.002
[2] 刘国涛, 朱玉翠, 张涛, 等.酒精性肝病研究进展[J].世界华人消化杂志, 2017, 25(15):1382.
[3] SHALANSKY SJ, VU T, PATE GE, et al.N-acetylcysteine for prevention of radiographic contrast material-induced nephropathy:is the intravenous route best?[J].Pharmacotherapy, 2005, 25(8):1095. doi: 10.1592/phco.2005.25.8.1095
[4] DINIZ YS, ROCHA KK, SOUZA GA, et al.Effects of N-acetylcysteine on sucrose-rich diet-induced hyperglycaemia, dyslipidemia and oxidative stress in rats[J].Eur J Pharm, 2006, 543(1/3):151.
[5] EL-LAKKANY NM, SEIF EL-DIN SH, SABRA AA, et al.Co-administration of metformin and N-acetylcysteine with dietary control improves the biochemical and histological manifestations in rats with non-alcoholic fatty liver[J].Res Pharm Sc, 2016, 11(5):374.
[6] TSE HN.Update on the pathological processes, molecular biology, and clinical utility of N-acetylcysteine in chronic obstructive pulmonary disease[J].Int J Chron Obstruct Pulmon Dis, 2014, 9:825.
[7] CHEN AT, CHIBNALL JT.Placebo-controlled augmentation trials of the antioxidant NAC in schizophrenia:A review[J].Ann Clin Psychiatry, 2016, 28(3):190.
[8] MAYER PGK, QVARTSKHAVA N, SOMMERFELD A, et al.Regulation of plasma membrane localization of the na+-taurocholate co-transporting polypeptide by glycochenodeoxycholate and tauroursodeoxycholate[J].Cell Physiol Biochem, 2019, 52(6):1427.
[9] DING Y, KO SC, MOON SH, et al.Protective effects of novel antioxidant peptide purified from alcalase hydrolysate of velvet antler against oxidative stress in chang liver cells in vitro and in a zebrafish model in vivo[J].Int J Mol Sc, 2019, 20(20):E5187. doi: 10.3390/ijms20205187
[10] XU ZJ, JIA YL, WANG M, et al.Effect of promoter, promoter mutation and enhancer on transgene expression mediated by episomal vectors in transfected HEK293, Chang liver and primary cells[J].Bioengineered, 2019, 10(1):548.
[11] ZHAO Y, CAI H, ZHOU P, et al.Protective effect of ulinastatin on hepatic ischemia reperfusion injury through autophagy activation in Chang liver cells[J].J Cell Biochem, 2019, 120(9):14960. doi: 10.1002/jcb.28758
[12] 刘吉云.人参超微粉中人参皂苷对肝细胞酒精性损伤的保护作用[D].长春: 吉林大学, 2016.
[13] 付裕, 郎涵, 陈柚伶, 等.葛黄颗粒含药血清对乙醇诱导L-02肝细胞损伤的保护作用及其机制研究[J].重庆医学, 2018, 47(20):2654. doi: 10.3969/j.issn.1671-8348.2018.20.003
[14] 中华医学会肝病学分会脂肪肝和酒精性肝病学组.酒精性肝病诊疗指南[J/CD].中国肝脏病杂志(电子版), 2010, 2(4): 49.
[15] REHM J, GMEL GE, GMEL G, et al.The relationship between different dimensions of alcohol use and the burden of disease-an update[J].Addiction (Abingdon, England), 2017, 112(6):968.
[16] World Health Organization.Global status report on alcohol and health 2018.2018.https://www.who.int/substance_abuse/publications/global_alcohol_report/en/
[17] GASKILL CL, MILLER LM, MATTOON JS, et al.Liver histopathology and liver and serum alanine aminotransferase and alkaline phosphatase activities in epileptic dogs receiving phenobarbital[J].Vet Pathol, 2005, 42(2):147.
[18] KISAOGLU A, OZOGUL B, TURAN MI, et al.Damage induced by paracetamol compared with N-acetylcysteine[J].JCMA, 2014, 77(9):463.
[19] KALIMERIS K, BRIASSOULIS P, NTZOUVANI A, et al.N-acetylcysteine ameliorates liver injury in a rat model of intestinal ischemia reperfusion[J].J Surg Res, 2016, 206(2):263.
[20] YI D, HOU Y, WANG L, et al.Dietary N-acetylcysteine supplementation alleviates liver injury in lipopolysaccharide-challenged piglets[J].Br J Nutr, 2014, 111(1):46.
[21] XUE M, LIU Y, LYU R, et al.Protective effect of aplysin on liver tissue and the gut microbiota in alcohol-fed rats[J].PLoS One, 2017, 12(6):e0178684. doi: 10.1371/journal.pone.0178684
[22] TILG H.Cytokines in alcoholic and nonalcoholic steatohepatitis[J].New Engl J Med, 2000, 343(20):1467.
[23] GYONGYI S, SHASHI B.Alcoholic liver disease and the gut-liver axis[J].World J Gastroentrol, 2010, 16(11):1321. doi: 10.3748/wjg.v16.i11.1321
[24] YIN M, WHEELER MD, KONO H, et al.Essential role of tumor necrosis factor α in alcohol-induced liver injury in mice[J].Gastroenterology, 1999, 117(4):942.
[25] MCCLAIN CJ, SONG Z, BARVE SS, et al.Recent advances in alcoholic liver disease Ⅳ dysregulated cytokine metabolism in alcoholic liver disease[J].Am J Physiol Gastr Liv Physiol, 2004, 287(3):G497.
[26] ASLAN GI, OTGUN I, ACER T, et al.The effect of intraperitoneal N-acetylcysteine on postoperative adhesions in rat models[J].Ann Ital Chir, 2017, 88:258.
[27] CHU DI, LIM R, HEYDRICK S, et al.N-acetyl-l-cysteine decreases intra-abdominal adhesion formation through the upregulation of peritoneal fibrinolytic activity and antioxidant defenses[J].Surgery, 2011, 149(6):801.
[28] CHANG YY, LIU YC, KUO YH, et al.Effects of antrosterol from Antrodia camphorata submerged whole broth on lipid homeostasis, antioxidation, alcohol clearance, and anti-inflammation in livers of chronic-alcohol fed mice[J].J Ethnopharmacol, 2017, 202:200.
[29] MANI V, ARIVALAGAN S, SIDDIQUE AI, et al.Antioxidant and anti-inflammatory role of zingerone in ethanol-induced hepatotoxicity[J].Mol Cell Biochem, 2016, 421(1/2):169.
[30] YESILOVA Z, YAMAN H, OKTENLI C, et al.Systemic markers of lipid peroxidation and antioxidants in patients with nonalcoholic Fatty liver disease[J].Am J Gastroenterol, 2005, 100(4):850.
[31] NAGATA K, SUZUKI H.Common pathogenic mechanism in development progression of liver injury caused by non-alcoholic or alcoholic steatohepatitis[J].J Toxicol Sci, 2007, 32(5):453.