[2] Culig Z,Hobisch A,Cronauer MC,et al.Regulation of prostatic growth and function by peptide growth factors[J].Prostate,1996,28(6):392-405.
[2] Emberton M,Andriole GL,de la Rosette J,et al.Benign prostatic hyperplasia:a progressive disease of aging men[J].Urology,2003,61(2):267-263.
[3] Smith P,Rhodes NP,Ke Y,et al.Relationship between upregulated oestrogen receptors and expression of growth factors in cultured human prostatic stromal cells exposed to estradiol or dihydrotestosterone[J].Prostate Cancer Prostatic Dis,2004,7(1):57-62.
[4] Smith P,Rhodes NP,Ke Y,et al.Upregulation of estrogen and androgen receptors modulate expression of FGF-2 and FGF-7 in human,cultured,prostatic stromal cells exposed to high concentrations of estradiol[J].Prostate Cancer Prostatic Dis,2002,5(2):105-110.
[5] Gann PH,Klein KG,Chatterton RT,et al.Growth factors in expressed prostatic fluid form men with prostate cancer,BPH,and clinically normal prostates[J].Prostate,1999,40(4):248-255.
[6] 贾彬,汤泓,李为民,等.表皮生长因子对小鼠前列腺细胞bcl-2,bax和c-myc基因表达水平的影响[J].中国老年学杂志,2007,2(27):251-252.
[7] 韩丽华,孙佩杰,王和,等.表皮生长因子受体和转化生长因子受体对前列腺增生和癌变组织及其预后判断的影响[J].中国临床康复,2005,9(6):108-109.
[8] 孙宏斌,夏术阶.表皮生长因子在前列腺带性结构中的分布及意义[J].中华泌尿外科杂志,2005,26(6):390-392.
[9] 韩丽华,王和,王嘉伦,等.转化生长因子在前列腺增生中作用的研究[J].沈阳医学院学报,2003,5(2):73-75.
[10] Blanchre M,Mestayer C,Saunier E,et al.Transforming growth factor in the human prostate:its role in stromal-epithelial interactions in non-cancerous cell culture[J].Prostate,2001,46(4):311-318.
[11] Bretland AJ,Reid SV,Chapple CR,et al.Role of endogenous transforming growth factor in prostatic stromal cells[J].Prostate,2001,48(4):297-304.
[12] 顾衡,董章霞,王昌兵,等.bFGF和TGF-对原代培养的前列腺间质细胞的作用[J].中国男科学杂志,2006,12(10):917-922.
[13] 牛远杰,马腾骧,张琚,等.转化生长因子1对前列腺基质细胞基因表达的调节作用[J].中华泌尿外科杂志,2001,22(12):754-756.
[14] 李月明,李玉魁,候淑兰,等.良性前列腺增生组织中细胞外基质与转化生长因子的研究[J].中华泌尿外科杂志,1995,16(7):421-422.
[15] Untergasser G,Gander R,Lilg C,et al.Profiling molecular targets of TGF- in prostate fibroblast to myofiboblast transdifferentiation[J].Mech Ageing Dev,2005,126(1):59-69.
[16] Howard PS,Kucich U,Coplen DE,et al.Transforming growth factor--induced hypertrophy and matrix expression in human bladder smooth muscle cells[J].Urology,2005,66(6):1349-1353.
[17] Toshihiro H,Naoki I,Kazuhiro S,et al.Modulation of phenotype of human prostatic stromal cells by transforming growth factor [J].Prostate,2004,58(2):174-182.
[18] Dow JK,devere White RW.Fibroblast growth factor 2:its structure and property,paracrine function,tumor angiogenesis and prostate related mitogenic and oncogenic functions[J].Urology,2000,55(6):800-806.
[19] Huang X,Lee C.Regulation of stmrnal proliferation,growth al-rest,differention and apoptosis in benign prostatic hyperplasia by TGF-[J].Front Biosci,2003(8):S740-S749.
[20] 武淑芳,屠曾宏.多肽类生长因子对前列腺生长和功能的调节[J].生理科学进展,2002,33(1):56-58.
[21] Ma QJ,Gu XQ,Cao X,et al.Effector of radiation on FGF- and bFGF expression in hyperplastic prostatic tissues[J].Asian J Androl,2005,7(1):49-54.
[22] 刘艳波,沈维高,赵雪俭.碱性成纤维细胞生长因子在前列腺癌和良性前列腺增生组织中表达的意义[J].中国老年学杂志,2007,27(14):1392-1393.
[23] 李路平,马庆杰,赵劼,等.辐射对前列腺增生组织中TGF-1和bFGF表达的影响[J].中国老年学杂志,2005,25(7):789-790.
[24] Berger AP,Kofler K,Bektic J,et al.Increased growth factor production in a human prostatic stromal cell culture model caused by hypoxia[J].Prostate,2003,57(1):57-65.
[25] Boget S,Leriche A,Revol A.Basic fibroblast growth factor and Keratinocyte growth factor overexpression in benign postatic hyperplasia[J].Farmaco,2001,56(5/7):467-469.
[26] Sherwood ER,Fong CJ,Lee C,et al.Basic fibroblast growth factor:a potential mediator of stromal growth in human prostate[J].Endocrinology,1992,130(5):2955-2963.
[27] Chan JM,Stampfer MJ,Giovannucci E,et al.Plasma insulin-like growth factor Ⅰ and prostate cancer risk:a prospective study[J].Science,1998,279(5350):563-566.
[28] Statttin P,Kaaks R,Riboli E,et al.Circulating insulin-like growth factor Ⅰ and benign prostatic hyperplasia prospective study[J].Scand J Urol Nephrol,2001,35(2):122-126.
[29] Dupont J,LeRoith D.Insulin and insulin-like growth factor Ⅰ receptors:similarities and differences in signal transduc-tion[J].Horm Res,2001,55(Suppl 2):22-26.
[30] Kleinberg DL,Ruan W,Yee D,et al.Insulin-like growth factor-Ⅰ controls prostate fibromuscular development:IGF-Ⅰ inhibition prevents both fibromuscular and glandular development in eugonadal mice[J].Endocrinology,2007,148(3):1080-1088.
[31] Trojan l,Bode C,Weiss C,et al.IGF-Ⅱ serum levels increase discrimination between benign prostatic hyperplasia and prostate cancer and improve the predictive value of PSA in clinical staging[J].Eur Urol,2006,49(2):286-292.
[32] Soulitzis N,Karyotis I,Delakas D,et al.Expression analysis of peptide growth factors VEGF,FGF2,TGFb1,EGF and IGF1 in prostate cancer and benign prostatic hyperplasia[J].Int J Oncol,2006,29(2):305-314.
[33] Sarma AV,Jaffe CA,Scbottenfeld D,et al.Insulin-like growth factor Ⅰ,insulin-like growth factor binding protein-3,and body mass index:clinical correlates of prostate volume among black men[J].Urology,2002,59(3):362-367.
[34] Chokkalingam AP,Gao T,Deng J,et al.Insulin-like growth factors and risk of benign prostatic hyperplasia[J].Prostate,2002,52(2):98-105.
[35] Monti S,Di Silverio F,Lraci R,et al.Regional variations of insulin-like growth factorⅠ,IGF-Ⅱ,and receptortype Ⅰin benign prostatic hyperplasia tissue and their correlation with intraprostatic androgens[J].Clin Endocrinol Metab,2001,86(4):1700-1706.
[36] 姜宁,贺伟,叶敏,等.血清IGF-1和IGFBP-3检测在前列腺癌和前列腺增生诊断中的临床意义[J].临床泌尿外科杂志,2004,19(4):216-218.
[37] 姜辉,叶海云,许清泉,等.Bcl-2和IGF-ⅠmRNA在正常和增生前列腺组织中表达及意义[J].中华泌尿外科杂志,2001,15(1):20-22.