[1] Engelman JA,Zhang XL,Lisanti MP.Genes encoding human caveolin-1 and-2 are co-localized to the D7S522 locus( 7q31.1),a known fragile site( FRA7G) that is equently deleted in human cancers[J].FEBS Lett,1998,436( 3):403-410.
[2] Chene L,Giroud C,Desgrandchamps F, et al.Extensive analysis of the7q31region in human prostate tumors supports TES as the best candidate tumor suppressor gene [J].Int J Cancer,2004,111( 5):798-804.
[3] Smart EJ,Graf GA,Mcniven MA, et al.Caveolins, liquid-ordered domains,and signal transduetion [J].Mol Cell Biol,1999,19( 11):7289-7304.
[4] Suyama T,Furuya M,Nishiyama M,et al.Up- regulation of the interferon gamma ( IFN-gamma ) -inducible chemokines IFNinducible T-cell alpha chemoattractant and monokine induced by IFN-gamma and of their receptor CXC receptor 3 in human renal cell carcinoma[J].Cancer, 2005,103( 2):258-267.
[5] Labrecque L,Royak I,Suprenant DS, et al.Regulation of vascular endotihelial gnowth factor receptor-2 activity by caveolin-1 and plasma membrane cholesterol[J].Mol Biol Cell,2003,14 ( 1 );334-347.
[6] 房凯,刘军.Caveolin-1 对内皮细胞增殖的抑制作用研究[J].中国肿瘤生物治疗杂志,2007, 14( 1):81-82.
[7] Hatanaka M,Maeda T, Ikemoto T, et al.Expression of caveolin-1 in human T cell leukemia cell lines[J].Biochem Biophys Res Commun, 1998,253( 2):382-387.
[8] 徐阳炎,杨慧龄,涂剑,等.pcDNA3.1 /NT2GFP 小凹蛋白1 及突变体表达载体的构建及功能分析[J].中国动脉硬化杂志,2005, 13( 3):297-300.
[9] 罗迪贤,杨慧龄,廖端芳,等.Caveolae /caveolins 与病毒感染[J].生理科学进展,2004, 35( 4):321-324.
[10] Galbiati F,Volonte D,Liu J, et al.Caveolin-1 expression negafively regtdates cell cycle progression by inducing CD, clarrest via a p53 /p21WAFI /Cipl-dependem mechanism[J].Mol Biol Cell,2001,12( 8):2229-2244.
[11] 罗红梅,唐圣松,廖瑞芳,等.Caveolin-1 基因转染对人胃腺癌细胞生长的影响[J].南华大学学报,2007, 35( 2):147-149.
[12] Esteller M,Corn PG,Baylin SB, et al.A gene hyperme thrlation profile of human cancer [J].Cancer Res,2001,61 ( 8 ):3225-3229.
[13] Engelman JA,Zhang XL,Lisanti MP.Sequence and detailed organization of the hum an caveolin-1 and -2 genes located near the D7S522 locus( 7q31.1).Methylation of a CpG island in the 5'promoterregion of the caveolin-1 gene in human breast cancer cell lines[J].FEBS Lett,1999,448( 2 /3):221-230.
[14] Mattson MP.Membrane microdomain signaling lipid rafts in biology and medicine[M].Totowa,NJ:Humana Press,2005:161-190.
[15] Lee H,Park DS,Razani B, et al.Caveolin-1 mutations( P132Land Nul1) and the pathogenesis of breast cancer[J].Am J Pathol,2002, 161( 4):1357-1369.
[16] Van den Eyn den GG,Van Laere SJ,Van der Auwera J,et al.Overexpression of eaveolin-1 and -2 in cell lines and in human samples of inflammatory breast cancer[J].Breast Cancer Res Treat, 2006,95( 3):219-228.
[17] Schlegel A,Aryan P,Lisanti MP.Caveolin-1 binding to endoplasm is reticulum membranes and entry into the regulated secretory pathway are regulated by serine phosphorylation Protein sorting at the level of the endoplasm is reticnlum[J].J Biol Chem,2001,276( 6):4398-4408.
[18] Yang G,Tmrme TL,Frolov A,et al.Combined c-Myc and caveolin-1 expression in human prostate carcinoma predicts prostate carcinoma progression [J].Cancer,2005,103 ( 6 ):1186-1194.
[19] 王涛,徐建江,徐友涛,等.膀胱癌中Caveolin-1 的表达及意义[J].临床与实验病理学杂志,2010,26( 5):616-618.
[20] Savage K,Lambros MB,Robertson D,et al.Caveolin 1 is overexpressed and amplified in a subset of basal-like and metaplastic breast carein omas:a morphologic,ultrastructural,immunohistochemical,and in situ hybridization an alysis[J].Clin Cancer Res, 2007, 13( 1):90-101.
[21] 杨聪颖,张志梅,王巧,等.胃癌组织中Caveolin-1,Paxillin 的表达及其临床生物学意义[J].现代肿瘤医学,2010, 18( 11):2211-2214.
[22] Burgermeister E,Xing XB,Rocken C, et al Differential expression and function of caveolin-1 in human gastric cancer progression[J].Cancer Res,2007,67( 18):8519-8526.
[23] Wiechen K,Diatchenko L,Agoulnik A, et al.Caveolin-1 is downregulated in human ovarian carcinoma and acts as a candidate tumor suppressor gene [J].Am J Pathol,2001,159 ( 5 ):1635-1643.
[24] Han SE,Park KH,Lee G, et al.Mutation and aberrant expression of Caveolin-1 in human oral squamous cell carcinomas and oral cancer cell lines[J].lnt J Oncol,2004,24( 2):435-440.
[25] 高冰芳,杨悦,杨晶晶,等.Dnmt1, caveolin-1 在结直肠癌中的表达及其临床意义[J].辽宁医学院学报,2010, 32( 1):9-11.
[26] Jemal A,Siegel R,Ward E, et al.Cancer statistics[J].CA Cancer J Clin, 2006,56( 2):106-130.
[27] Hundahl SA,Fleming ID,Fremgen AM, et al.A National Cancer Data Base report on 53 856 cases of thyroid carcinoma treated in the U.S.1985-1995[J].Cancer,1998,83( 12):2638-2648.
[28] Ito Y,Yoshida H,Nakano K, et al.Caveolin-1 overexpression is an early event in progression of papillary carcinoma of the thyroid[J].Br J Cancer,2002, 86( 6):912-916.
[29] 刘雅林,刘宏侠.Caveolin-1 和pEPK1 /2 在甲状腺乳头状癌肿的表达及意义[J].实用预防医学, 2009,16( 3):692-695.
[30] Lee H,Volonte D,Galbiati F, et al.Constitutive and growth factor regulated phosphorylation of caveolin-1 occurs at the same site ( Tyr14) in vivo:identification of a c-Src /Cav-1 /Grb7 signaling cassette[J].Mol Endocrinol,2000, 14( 11):1750-1775.
[31] 黄清丽,皇甫辉,史敏,等.喉鳞癌caveolin-1 和MVD 表达及与颈淋巴结转移的关系[J].中国医学导报,2011,8 ( 8 ):1673-7210.
[32] Bender FC,Reymond MA,Bron C,et al.Caveolin-1 levels are down regulated in human colon tumors,and ectopic expression of caveolin-1 in colon carcinoma cell lines reduces cell tumorigenicity[J].Cancer Res, 2000,60( 20):5870-5878.
[33] Lin MI,Yu J,Murata T,et al.Caveolin-1 deficient mice have incleased tumor microvascular permeability,angiogenesis,and growth[J].Cancer Res,2007, 67( 6):2849-2856.
[34] Park JH,Lee MY,Han HJ.A potential role for caveolin-1 in estradiol-17beta-induced proliferation of mouse embryonic stem cells:involvement of Sre,P13K/Akt,and MAPKs pathways[J].Int J Biochem Cell Biol, 2009,41( 3):659-665.
[35] Puddu A,Salani B,Cordera R,et al.Caveolin-1 is essential forglimepiride-induced insulin secretion in the pancreatic betaTC-6 cell line[J].Biochem Biophys Res Commun,2008,375 ( 2):235-237.