[1] KRENK L, RASMUSSEN LS, KEHLET H. New insights into the pathophysiology of postoperative cognitive dysfunction[J]. Acta Anaesthesiol Scand, 2010, 54(8): 951. doi: 10.1111/j.1399-6576.2010.02268.x
[2] BELROSE JC, NOPPENS RR. Anesthesiology and cognitive impairment: a narrative review of current clinical literature[J]. BMC Anesthesiol, 2019, 19(1): 241. doi: 10.1186/s12871-019-0903-7
[3] KRISTEK G, RADOŠ I, KRISTEK D, et al. Influence of postoperative analgesia on systemic inflammatory response and postoperative cognitive dysfunction after femoral fractures surgery: a randomized controlled trial[J]. Reg Anesth Pain Med, 2019, 44(1): 59. doi: 10.1136/rapm-2018-000023
[4] MA G, CHEN C, JIANG H, et al. Ribonuclease attenuates hepatic ischemia reperfusion induced cognitive impairment through the inhibition of inflammatory cytokines in aged mice[J]. Biomed Pharmacother, 2017, 90: 62. doi: 10.1016/j.biopha.2017.02.094
[5] QIAN XL, ZHANG W, LIU MZ, et al. Dexmedetomidine improves early postoperative cognitive dysfunction in aged mice[J]. Eur J Pharmacol, 2015, 746: 206. doi: 10.1016/j.ejphar.2014.11.017
[6] CHEN N, CHEN X, XIE J, et al. Dexmedetomidine protects aged rats from postoperative cognitive dysfunction by alleviating hippocampal inflammation[J]. Mol Med Rep, 2019, 20(3): 2119.
[7] LI Y, HE R, CHEN S, et al. Effect of dexmedetomidine on early postoperative cognitive dysfunction and peri-operative inflammation in elderly patients undergoing laparoscopic cholecystectomy[J]. Exp Ther Med, 2015, 10(5): 1635. doi: 10.3892/etm.2015.2726
[8] ZHANG H, WU Z, ZHAO X, et al. Role of dexmedetomidine in reducing the incidence of postoperative cognitive dysfunction caused by sevoflurane inhalation anesthesia in elderly patients with esophageal carcinoma[J]. J Cancer Res Ther, 2018, 14(7): 1497. doi: 10.4103/jcrt.JCRT_164_18
[9] DAI T, DAVEY A, WOODARD JL, et al. Sources of variation on the mini-mental state examination in a population-based sample of centenarians[J]. J Am Geriatr Soc, 2013, 61(8): 1369. doi: 10.1111/jgs.12370
[10] BERGER M, NADLER JW, BROWNDYKE J, et al. Postoperative cognitive dysfunction: minding the gaps in our knowledge of a common postoperative complication in the elderly[J]. Anesthesiol Clin, 2015, 33(3): 517. doi: 10.1016/j.anclin.2015.05.008
[11] MOLLER JT, CLUITMANS P, RASMUSSEN LS, et al. Long-term postoperative cognitive dysfunction in the elderly ISPOCD1 study. ISPOCD investigators. International Study of Post-Operative Cognitive Dysfunction[J]. Lancet, 1998, 351(9106): 857. doi: 10.1016/S0140-6736(97)07382-0
[12] LI YC, XI CH, AN YF, et al. Perioperative inflammatory response and protein S-100β concentrations-relationship with post-operative cognitive dysfunction in elderly patients[J]. Acta Anaesthesiol Scand, 2012, 56(5): 595. doi: 10.1111/j.1399-6576.2011.02616.x
[13] WAN Y, XU J, MA D, et al. Postoperative impairment of cognitive function in rats: a possible role for cytokine-mediated inflammation in the hippocampus[J]. Anesthesiology, 2007, 106(3): 436.
[14] CAI Y, XU H, YAN J, et al. Molecular targets and mechanism of action of dexmedetomidine in treatment of ischemia/reperfusion injury[J]. Mol Med Rep, 2014, 9(5): 1542. doi: 10.3892/mmr.2014.2034
[15] DARDALAS I, STAMOULA E, RIGOPOULOS P, et al. Dexmedetomidine effects in different experimental sepsis in vivo models[J]. Eur J Pharmacol, 2019, 856: 172401. doi: 10.1016/j.ejphar.2019.05.030