[1] 陈伟伟, 高润霖, 刘力生, 等. 《中国心血管病报告2017》概要[J]. 中国循环杂志, 2018, 33(1): 1.
[2] TIAPKO O, GROSCHNER K.TRPC3 as a Target of Novel Therapeutic Interventions[J]. Cells, 2018, 7(7): E83. doi: 10.3390/cells7070083
[3] COSENS DJ, MANNING A.Abnormal electroretinogram from a Drosophila mutant[J]. Nature, 1969, 224(5216): 285. doi: 10.1038/224285a0
[4] PEDERSEN SF, OWSIANIK G, NILIUS B.TRP channels: an overview[J]. Cell Calcium, 2005, 38(3/4): 233.
[5] PAN Z, YANG H, REINACH PS.Transient receptor potential (TRP) gene superfamily encoding cation channels[J]. Hum Genomics, 2011, 5(2): 108. doi: 10.1186/1479-7364-5-2-108
[6] TREBAK M, VAZQUEZ G, BIRD GS, et al. The TRPC3/6/7 subfamily of cation channels[J]. Cell Calcium, 2003, 33(5/6): 451.
[7] 金萍萍, 王亚娟, 王彦, 等. 瞬时受体电位通道C3、C6在高血压发病中的作用[J]. 上海医药, 2015, 36(24): 21.
[8] YUE Z, XIE J, YU AS, et al. Role of TRP channels in the cardiovascular system[J]. Am J Physiol Heart Circ Physiol, 2015, 308(3): H157. doi: 10.1152/ajpheart.00457.2014
[9] VASSORT G, ALVAREZ J.Transient receptor potential: a large family of new channels of which several are involved in cardiac arrhythmia[J]. Can J Physiol Pharmacol, 2009, 87(2): 100. doi: 10.1139/Y08-112
[10] HOFMANN T, SCHAEFER M, SCHULTZ G, et al. Subunit composition of mammalian transient receptor potential channels in living cells[J]. Proc Natl Acad Sci U S A, 2002, 99(11): 7461. doi: 10.1073/pnas.102596199
[11] FAN C, CHOI W, SUN W, et al. Structure of the human lipid-gated cation channel TRPC3[J]. eLife, 2018, 7: e36852. doi: 10.7554/eLife.36852
[12] TANG Q, GUO W, ZHENG L, et al. Structure of the receptor-activated human TRPC6 and TRPC3 ion channels[J]. Cell Res, 2018, 28(7): 746. doi: 10.1038/s41422-018-0038-2
[13] 卢敏, 祝晓莹, 吴太鼎. TRPC的激活机制研究现状[J]. 农垦医学, 2014, 36(4): 337. doi: 10.3969/j.issn.1008-1127.2014.04.016
[14] DEMAUREX N, FRIEDEN M.Measurements of the free luminal ER Ca(2+) concentration with targeted "cameleon" fluorescent proteins[J]. Cell Calcium, 2003, 34(2): 109. doi: 10.1016/S0143-4160(03)00081-2
[15] 郑思思, 项楠, 赵福宽. 内质网钙池操控钙内流研究进展[J]. 生物技术进展, 2017, 7(2): 121.
[16] EDER P.Cardiac remodeling and disease: SOCE and TRPC signaling in cardiac pathology[J]. Adv Exp Med Biol, 2017, 993: 505.
[17] LIAO Y, ERXLEBEN C, YILDIRIM E, et al. Orai proteins interact with TRPC channels and confer responsiveness to store depletion[J]. Proc Natl Acad Sci U S A, 2007, 104(11): 4682. doi: 10.1073/pnas.0611692104
[18] LEMONNIER L, TREBAK M, PUTNEY JW JR.Complex regulation of the TRPC3, 6 and 7 channel subfamily by diacylglycerol and phosphatidylinositol-4, 5-bisphosphate[J]. Cell Calcium, 2008, 43(5): 506. doi: 10.1016/j.ceca.2007.09.001
[19] GRAZIANI A, ROSKER C, KOHLWEIN SD, et al. Cellular cholesterol controls TRPC3 function: evidence from a novel dominant-negative knockdown strategy[J]. Biochem J, 2006, 396(1): 147. doi: 10.1042/BJ20051246
[20] LICHTENEGGER M, TIAPKO O, SVOBODOVA B, et al. An optically controlled probe identifies lipid-gating fenestrations within the TRPC3 channel[J]. Nat Chem Biol, 2018, 14(4): 396. doi: 10.1038/s41589-018-0015-6
[21] SMYTH JT, LEMONNIER L, VAZQUEZ G, et al. Dissociation of regulated trafficking of TRPC3 channels to the plasma membrane from their activation by phospholipase C[J]. J Biol Chem, 2006, 281(17): 11712. doi: 10.1074/jbc.M510541200
[22] WANG Q, WANG D, YAN G, et al. TRPC6 is required for hypoxia-induced basal intracellular calcium concentration elevation, and for the proliferation and migration of rat distal pulmonary venous smooth muscle cells[J]. Mol Med Rep, 2016, 13(2): 1577. doi: 10.3892/mmr.2015.4750
[23] PENG G, LI S, HONG W, et al. Chronic hypoxia increases intracellular Ca(2+) concentration via enhanced Ca(2+) entry through receptor-operated Ca(2+) channels in pulmonary venous smooth muscle cells[J]. Circ J, 2015, 79(9): 2058. doi: 10.1253/circj.CJ-15-0067
[24] 贾旭广, 郑梦晓, 张晶晶, 等. TRPC6在低氧高二氧化碳肺动脉平滑肌细胞增殖、凋亡中的作用[J]. 生理学报, 2017, 69(1): 47.
[25] CHEN GL, JIANG H, ZOU F.Upregulation of transient receptor potential canonical channels contributes to endotoxin-induced pulmonary arterial stenosis[J]. Med Sci Monit, 2016, 22: 2679. doi: 10.12659/MSM.898111
[26] JIANG HN, ZENG B, CHEN GL, et al. Lipopolysaccharide potentiates endothelin-1-induced proliferation of pulmonary arterial smooth muscle cells by upregulating TRPC channels[J]. Biomed Pharmacother, 2016, 82: 20. doi: 10.1016/j.biopha.2016.04.055
[27] JUNLI H, HONGYAN T, YA L, et al. 5-HT promotes pulmonary arterial smooth muscle cell proliferation through the TRPC channel[J]. Cell Mol Biol (Noisy-le-grand), 2018, 64(13): 89. doi: 10.14715/cmb/2018.64.13.17
[28] MACHIDA T, ONOGUCHI A, ⅡZUKA K, et al. Effect of docosahexaenoic acid on voltage-independent Ca2+ entry pathways in cultured vascular smooth muscle cells stimulated with 5-Hydroxytryptamine[J]. Biol Pharm Bull, 2017, 40(6): 916. doi: 10.1248/bpb.b16-00788
[29] 李晓岩, 冉丕鑫, 王健. 骨形态形成蛋白4通过受体Ⅱ/Smad信号通路对瞬时受体电离子通道蛋白表达的影响[J]. 中华结核和呼吸杂志, 2016, 39(7): 539. doi: 10.3760/cma.j.issn.1001-0939.2016.07.010
[30] JIANG Q, LU W, YANG K, et al. Sodium tanshinone ⅡA sulfonate inhibits hypoxia-induced enhancement of SOCE in pulmonary arterial smooth muscle cells via the PKG-PPAR-γ signaling axis[J]. Am J Physiol Cell Physiol, 2016, 311(1): C136. doi: 10.1152/ajpcell.00252.2015
[31] NAKAMURA H, ZIMMER J, LIM T, et al. Increased CaSR and TRPC6 pulmonary vascular expression in the nitrofen-induced model of congenital diaphragmatic hernia[J]. Pediatr Surg Int, 2018, 34(2): 211. doi: 10.1007/s00383-017-4191-3
[32] TANG H, YAMAMURA A, YAMAMURA H, et al. Pathogenic role of calcium-sensing receptors in the development and progression of pulmonary hypertension[J]. Am J Physiol Lung Cell Mol Physiol, 2016, 310(9): L846. doi: 10.1152/ajplung.00050.2016
[33] KRAUSZMAN A, MAK TW, SZASZI K, et al. Role of phosphatase and tensin homolog in hypoxic pulmonary vasoconstriction[J]. Cardiovasc Res, 2017, 113(8): 869. doi: 10.1093/cvr/cvx076
[34] EARLEY S, BRAYDEN JE.Transient receptor potential channels in the vasculature[J]. Physiol Rev, 2015, 95(2): 645. doi: 10.1152/physrev.00026.2014
[35] FENG S, LI H, TAI Y, et al. Canonical transient receptor potential 3 channels regulate mitochondrial calcium uptake[J]. Proc Natl Acad Sci U S A, 2013, 110(27): 11011. doi: 10.1073/pnas.1309531110
[36] WANG B, XIONG S, LIN S, et al. Enhanced mitochondrial transient receptor potential channel, canonical Type 3-mediated calcium handling in the vasculature from hypertensive rats[J]. J Am Heart Assoc, 2017, 6(7): e005812.
[37] ALVAREZ RE, BOELDT DS, PATTNAIK BR, et al. Pregnancy-adapted uterine artery endothelial cell Ca2+ signaling and its relationship with membrane potential[J]. Physiol Rep, 2017, 5(21): e13452. doi: 10.14814/phy2.13452
[38] KASSAHUN GEBREMESKEL A, WIJERATHNE TD, KIM JH, et al. Psoralea corylifolia extract induces vasodilation in rat arteries through both endothelium-dependent and -independent mechanisms involving inhibition of TRPC3 channel activity and elaboration of prostaglandin[J]. Pharm Biol, 2017, 55(1): 2136. doi: 10.1080/13880209.2017.1383484
[39] LIANG M, ZHONG W, MIAO F, et al. Effects of losartan on vasomotor function and canonical transient receptor potential channels in the aortas of sinoaortic denervation rats[J]. Clin Exp Hypertens, 2018, 40(1): 39. doi: 10.1080/10641963.2017.1299746
[40] OISHI S, SUZUKI N, HASUI Y, et al. Sustained activation of guanylate cyclase-A with TDT, a natriuretic peptide derivative, exhibits cardiorenal protection in dahl salt-sensitive hypertensive rats[J]. J Pharmacol Exp Ther, 2017, 363(3): 402. doi: 10.1124/jpet.117.244459
[41] HAN X, ROSS J, KOLUMAM G, et al. Cardiovascular effects of renal distal tubule deletion of the FGF receptor 1 gene[J]. J Am Soc Nephrol, 2018, 29(1): 69. doi: 10.1681/ASN.2017040412
[42] GOMART S, GAUDREAU-MÉNARD C, JESPERS P, et al. Leptin-Induced Endothelium-Independent vasoconstriction in thoracic aorta and pulmonary artery of spontaneously hypertensive rats: role of calcium channels and stores[J]. PLoS One, 2017, 12(1): e0169205. doi: 10.1371/journal.pone.0169205
[43] ÁLVAREZ-MIGUEL I, CIDAD P, PÉREZ-GARCÍA MT, et al. Differences in TRPC3 and TRPC6 channels assembly in mesenteric vascular smooth muscle cells in essential hypertension[J]. J Physiol, 2017, 595(5): 1497. doi: 10.1113/JP273327
[44] LIU FF, MA ZY, LI DL, et al. Differential expression of TRPC channels in the left ventricle of spontaneously hypertensive rats[J]. Mol Biol Rep, 2010, 37(6): 2645. doi: 10.1007/s11033-009-9792-z
[45] NUMAGA-TOMITA T, KITAJIMA N, KURODA T, et al. TRPC3-GEF-H1 axis mediates pressure overload-induced cardiac fibrosis[J]. Sci Rep, 2016, 6: 39383. doi: 10.1038/srep39383
[46] HAN JW, LEE YH, YOEN SI, et al. Resistance to pathologic cardiac hypertrophy and reduced expression of CaV1.2 in Trpc3-depleted mice[J]. Mol Cell Biochem, 2016, 421(1/2): 55.
[47] ZHANG Y, KNIGHT W, CHEN S, et al. Multiprotein complex with TRPC (transient receptor potential-canonical) channel, PDE1C (phosphodiesterase 1C), and A2R (adenosine A2 Receptor) plays a critical role in regulating cardiomyocyte cAMP and survival[J]. Circulation, 2018, 138(18): 1988. doi: 10.1161/CIRCULATIONAHA.118.034189
[48] KITAJIMA N, NUMAGA-TOMITA T, WATANABE M, et al. TRPC3 positively regulates reactive oxygen species driving maladaptive cardiac remodeling[J]. Sci Rep, 2016, 6: 37001. doi: 10.1038/srep37001
[49] HAN L, LI J.Canonical transient receptor potential 3 channels in atrial fibrillation[J]. Eur J Pharmacol, 2018, 837: 1. doi: 10.1016/j.ejphar.2018.08.030
[50] QI Z, WONG CK, SUEN CH, et al. TRPC3 regulates the automaticity of embryonic stem cell-derived cardiomyocytes[J]. Int J Cardiol, 2016, 203: 169. doi: 10.1016/j.ijcard.2015.10.018
[51] HOWARTH FC, QURESHI MA, JAYAPRAKASH P, et al. The pattern of mRNA expression is changed in sinoatrial node from Goto-Kakizaki type 2 diabetic rat heart[J]. J Diabetes Res, 2018, 2018: 8454078.