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内质网应激与自噬信号通路研究进展

宋乐乐 蒋琛琛

引用本文:
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内质网应激与自噬信号通路研究进展

    作者简介: 宋乐乐(1987-),女,硕士研究生.
    通讯作者: 蒋琛琛, chenchen_jiang@yahoo.com.cn
  • 基金项目:

    国家自然科学基金资助项目(81000992,81072207)

    安 徽省高校省级自然科学研究重点项目(KJ2012A202)

    安徽省自然科学基金资助项目(090413135)

Progress in the endoplasmic reticulum stress and autophagy signaling pathway

    Corresponding author: Jiang Chenchen Proofreading, chenchen_jiang@yahoo.com.cn
  • Fund Project: Project supported by the National Natural Science Fund (8100099281072207) the Anhui Provincial Natural Science Research Project (KJ2012A202) the natural science foundation of Anhui province (090413135)

  • 摘要: 真核细胞通过凋亡途径以应对内质网中未折叠蛋白的累积。目前,有数据证明内质网应激也是自噬的诱导因素,真核细胞循环利用大分子和细胞器,自噬平衡内质网应激诱导的内质网膨胀,促使细胞存活。
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  • 收稿日期:  2012-09-03
  • 刊出日期:  2014-05-15

内质网应激与自噬信号通路研究进展

    通讯作者: 蒋琛琛, chenchen_jiang@yahoo.com.cn
    作者简介: 宋乐乐(1987-),女,硕士研究生.
  • 1. 1. 蚌埠医学院第一附属医院 药剂科,安徽 蚌埠 233004;
  • 2.  2. 蚌埠医学院 药学系,安徽省生化药物工程技术研 究中心,安徽 蚌埠 233030
基金项目:  国家自然科学基金资助项目(81000992,81072207)安 徽省高校省级自然科学研究重点项目(KJ2012A202) 安徽省自然科学基金资助项目(090413135)

摘要: 真核细胞通过凋亡途径以应对内质网中未折叠蛋白的累积。目前,有数据证明内质网应激也是自噬的诱导因素,真核细胞循环利用大分子和细胞器,自噬平衡内质网应激诱导的内质网膨胀,促使细胞存活。

English Abstract

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