高血压脑出血患者血清雌二醇、睾酮的变化及临床意义

汪国胜; 钟平; 张雷; 张蕾; 马争飞; 刘彬

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高血压脑出血患者血清雌二醇、睾酮的变化及临床意义

汪国胜 , 钟平 , 张雷 , 张蕾 , 马争飞 , 刘彬

文章导航 > 蚌埠医学院学报 > 2014, 38 > 6: (745-748)

引用本文:

Citation:

高血压脑出血患者血清雌二醇、睾酮的变化及临床意义

1.
安徽省宿州市立医院神经内科, 234000

作者简介: 汪国胜(1968-)，男，副主任医师.

基金项目:

The serum level of estradiol and testosterone in patients with hypertensive intracerebral hemorrhage and its clinical significance

1.
Department of Neurology, Suzhou Municipal Hospital, Suzhou Anhui 234000, China

摘要: 目的：探讨高血压脑出血患者血清雌二醇、睾酮水平与病情程度及预后的相关性。方法：检测168例高血压脑出血患者(脑出血组)及60例对照组血清雌二醇、睾酮的含量，按美国国立卫生研究院卒中量表标准对患者进行评分，再按病情轻重及病程评分的差值分组比较。结果：男性脑出血组雌二醇和睾酮与对照组差异均有统计学意义(P＜0.01和P＜0.05)，男女脑出血组雌二醇/睾酮比值与对照组差异均无统计学意义(P>0.05)。男性患者轻度病情组血清雌二醇含量较中、重度组升高(PP>0.05)。男性患者少量出血组血清雌二醇和睾酮含量均较中量出血组升高(PP>0.05)。女性脑出血组雌二醇与对照组差异无统计学意义(P>0.05)，女性脑出血组睾酮与对照组差异有统计学意义(PPPPP0.05)。男、女性患者显著好转组雌二醇含量均较无变化组及恶化组升高(PPPPPP结论：高血压脑出血患者血清雌二醇、雌二醇/睾酮比值测定有助于判断预后。
- 脑出血 /
- 高血压/并发症 /
- 雌二醇 /
- 睾酮
Abstract: Objective:To investigate the serum levels of estradiol and testosterone in patients with hypertensive intracerebral hemorrhage and their relations with illness severity and prognosis.Methods:The serum levels of estradiol and testosterone in 168 patients with hypertensive intracerebral hemorrhage(cerebral hemorrhage group) and 60 healthy people(control group) were determined.All patients were scored by U.S.National Institutes of Health Stroke Scale,and compared in two groups.Results:The differences of the serum levels of estradiol and testosterone in male between two groups were statistically significant(PPP>0.05).The serum level of estradiol in male patient with mild illness was moderate,and high in severe patients(PP>0.05).The serum levels of estradiol and testosterone in male patients with small amount of bleeding were higher than those in male patients with median amount of bleeding(PP>0.05).The difference of the estradiol serum level in female between two groups was not statistically significant(P>0.05),but for testosteron difference,it was statistically significant(PPPPPP>0.05).Compared with the no change and deterioration patients,the serum levels of estradiol and testosterone and the ratio of estradiol and testosterone in patients with obvious improvement were significantly increased,decreased and incresed,respectively(PPConclusions:The serum level of estradiol and ratio of estradiol and testosterone in patients with hypertensive intracerebral hemorrhage are helpful for judging the disease prognosis.
- intracerebral hemorrhage /
- hypertension/complications /
- estradiol /
- testosterone

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高血压脑出血患者血清雌二醇、睾酮的变化及临床意义

作者简介: 汪国胜(1968-)，男，副主任医师.

1. 安徽省宿州市立医院神经内科, 234000

收稿日期: 2013-01-25
网络出版日期: 2014-06-15

基金项目:

关键词:

摘要: 目的：探讨高血压脑出血患者血清雌二醇、睾酮水平与病情程度及预后的相关性。方法：检测168例高血压脑出血患者(脑出血组)及60例对照组血清雌二醇、睾酮的含量，按美国国立卫生研究院卒中量表标准对患者进行评分，再按病情轻重及病程评分的差值分组比较。结果：男性脑出血组雌二醇和睾酮与对照组差异均有统计学意义(P＜0.01和P＜0.05)，男女脑出血组雌二醇/睾酮比值与对照组差异均无统计学意义(P>0.05)。男性患者轻度病情组血清雌二醇含量较中、重度组升高(PP>0.05)。男性患者少量出血组血清雌二醇和睾酮含量均较中量出血组升高(PP>0.05)。女性脑出血组雌二醇与对照组差异无统计学意义(P>0.05)，女性脑出血组睾酮与对照组差异有统计学意义(PPPPP0.05)。男、女性患者显著好转组雌二醇含量均较无变化组及恶化组升高(PPPPPP结论：高血压脑出血患者血清雌二醇、雌二醇/睾酮比值测定有助于判断预后。

English Abstract

The serum level of estradiol and testosterone in patients with hypertensive intracerebral hemorrhage and its clinical significance

1. Department of Neurology, Suzhou Municipal Hospital, Suzhou Anhui 234000, China

Received Date: 2013-01-25
Available Online: 2014-06-15

Abstract: Objective:To investigate the serum levels of estradiol and testosterone in patients with hypertensive intracerebral hemorrhage and their relations with illness severity and prognosis.Methods:The serum levels of estradiol and testosterone in 168 patients with hypertensive intracerebral hemorrhage(cerebral hemorrhage group) and 60 healthy people(control group) were determined.All patients were scored by U.S.National Institutes of Health Stroke Scale,and compared in two groups.Results:The differences of the serum levels of estradiol and testosterone in male between two groups were statistically significant(PPP>0.05).The serum level of estradiol in male patient with mild illness was moderate,and high in severe patients(PP>0.05).The serum levels of estradiol and testosterone in male patients with small amount of bleeding were higher than those in male patients with median amount of bleeding(PP>0.05).The difference of the estradiol serum level in female between two groups was not statistically significant(P>0.05),but for testosteron difference,it was statistically significant(PPPPPP>0.05).Compared with the no change and deterioration patients,the serum levels of estradiol and testosterone and the ratio of estradiol and testosterone in patients with obvious improvement were significantly increased,decreased and incresed,respectively(PPConclusions:The serum level of estradiol and ratio of estradiol and testosterone in patients with hypertensive intracerebral hemorrhage are helpful for judging the disease prognosis.