彩色多普勒超声在诊断三阴性乳腺癌中的应用

王萍; 童仙君; 程遵华; 郑颖; 项晓宇; 董晓燕; 黄菊琴; 张晓云; 薛晓红

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彩色多普勒超声在诊断三阴性乳腺癌中的应用

王萍 , 童仙君 , 程遵华 , 郑颖 , 项晓宇 , 董晓燕 , 黄菊琴 , 张晓云 , 薛晓红

文章导航 > 蚌埠医学院学报 > 2013, 37 > 2: (192-195)

引用本文:

Citation:

彩色多普勒超声在诊断三阴性乳腺癌中的应用

1.
1. 上海中医药大学附属岳阳中西医结合医院超声诊断科;
2.
2. 上海中医药大学附属岳阳中西医结合医院病理科;
3.
3. 上海中医药大学附属岳阳中西医结合医院乳腺科

作者简介: 王萍(1964 - )，女，副主任医师

基金项目:

Application of color Doppler ultrasound in triple negative breast cancer

1.
1. Department of Ultrasound Diagnosis,
2.
2. Department of Pathology,
3.
3. Department of Mammary Glands, Yueyang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200437, China

摘要: 目的:探讨彩色多普勒超声在诊断三阴性乳腺癌(TNBC)中的应用价值。方法:169例经彩色多普勒超声诊断乳腺占位性病变,并经手术和病理检查确诊为乳腺癌的患者,根据免疫组织化学染色检测雌激素受体(ER)、孕激素受体(PR)和人表皮生长因子受体2(HER2)表达情况,分为TNBC组37例和非TNBC组132例,分析比较2组的超声声像图、病理及临床情况。结果:与非TNBC组比较,TNBC组肿块有较清楚边界的比例高(P0.05),病灶边缘毛刺状的比例低(P0.05),病灶内部回声较低且较少钙化(P0.01),病灶后方声影较少衰减(P0.05),病灶内无血流或较少血流(P0.05),血流阻力指数0.7的比例高(P0.05)。TNBC组腋窝淋巴结转移高于非TNBC组(P0.05)。结论:TNBC在超声声像图上的表现更倾向于良性肿块。彩色多普勒超声检查在诊断TNBC方面可起到早期诊断或早期提示作用。
- 乳腺肿瘤 /
- 超声检查 /
- 雌激素受体 /
- 孕激素受体 /
- 人表皮生长因子受体2
Abstract: Objective:To investigate the value of color Doppler ultrasound in the diagnosis of triple negative breast cancer(TNBC).Methods:One hundred and sixty-nine cases of breast occupying lesions which were diagnosed by color Doppler ultrasound and confirmed as breast cancer by surgery and pathology were divided into TNBC groups(37 cases) and non-TNBC group(132 cases) according to the expression of estrogen receptor(ER),progesterone receptor(PR) and human epidermal growth factor receptor 2(HER2) determined by immunohistochemical staining.The ultrasonic image,pathological manifestation and clinical condition of the 2 groups were compared and analyzed.Results:Ultrasonic images showed that the TNBC group had a greater proportion in the masses with clear boundary and a smaller proportion in the masses with short burr on the edge than the non-TNBC group(P0.05);the TNBC group had lower echoes and less calcification than the non-TNBC group(P0.01),and its posterior sound shadow was less attenuated(P0.05);most of the masses in TNBC group showed no blood stream or little blood stream(P0.05);the proportion of flow resistance index0.7 in TNBC group was greater than that in non-TNBC group(P0.05).Pathological examinations showed that axillary lymph node metastases occurred more frequently in the TNBC group(P0.05).Conclusions:The above features make the mass more likely to be a benign one.The technique of color Doppler ultrasound is of use in the early diagnosis of TNBC.
- breast neoplasms /
- ultrasound /
- estrogen receptor /
- progesterone receptor /
- human epidermal growth factor receptor 2

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彩色多普勒超声在诊断三阴性乳腺癌中的应用

作者简介: 王萍(1964 - )，女，副主任医师

1. 1. 上海中医药大学附属岳阳中西医结合医院超声诊断科;
2. 2. 上海中医药大学附属岳阳中西医结合医院病理科;
3. 3. 上海中医药大学附属岳阳中西医结合医院乳腺科

收稿日期: 2012-03-14
网络出版日期: 2013-02-15

基金项目:

关键词:

摘要: 目的:探讨彩色多普勒超声在诊断三阴性乳腺癌(TNBC)中的应用价值。方法:169例经彩色多普勒超声诊断乳腺占位性病变,并经手术和病理检查确诊为乳腺癌的患者,根据免疫组织化学染色检测雌激素受体(ER)、孕激素受体(PR)和人表皮生长因子受体2(HER2)表达情况,分为TNBC组37例和非TNBC组132例,分析比较2组的超声声像图、病理及临床情况。结果:与非TNBC组比较,TNBC组肿块有较清楚边界的比例高(P0.05),病灶边缘毛刺状的比例低(P0.05),病灶内部回声较低且较少钙化(P0.01),病灶后方声影较少衰减(P0.05),病灶内无血流或较少血流(P0.05),血流阻力指数0.7的比例高(P0.05)。TNBC组腋窝淋巴结转移高于非TNBC组(P0.05)。结论:TNBC在超声声像图上的表现更倾向于良性肿块。彩色多普勒超声检查在诊断TNBC方面可起到早期诊断或早期提示作用。

English Abstract

Application of color Doppler ultrasound in triple negative breast cancer

1. 1. Department of Ultrasound Diagnosis,
2. 2. Department of Pathology,
3. 3. Department of Mammary Glands, Yueyang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200437, China

Received Date: 2012-03-14
Available Online: 2013-02-15

Abstract: Objective:To investigate the value of color Doppler ultrasound in the diagnosis of triple negative breast cancer(TNBC).Methods:One hundred and sixty-nine cases of breast occupying lesions which were diagnosed by color Doppler ultrasound and confirmed as breast cancer by surgery and pathology were divided into TNBC groups(37 cases) and non-TNBC group(132 cases) according to the expression of estrogen receptor(ER),progesterone receptor(PR) and human epidermal growth factor receptor 2(HER2) determined by immunohistochemical staining.The ultrasonic image,pathological manifestation and clinical condition of the 2 groups were compared and analyzed.Results:Ultrasonic images showed that the TNBC group had a greater proportion in the masses with clear boundary and a smaller proportion in the masses with short burr on the edge than the non-TNBC group(P0.05);the TNBC group had lower echoes and less calcification than the non-TNBC group(P0.01),and its posterior sound shadow was less attenuated(P0.05);most of the masses in TNBC group showed no blood stream or little blood stream(P0.05);the proportion of flow resistance index0.7 in TNBC group was greater than that in non-TNBC group(P0.05).Pathological examinations showed that axillary lymph node metastases occurred more frequently in the TNBC group(P0.05).Conclusions:The above features make the mass more likely to be a benign one.The technique of color Doppler ultrasound is of use in the early diagnosis of TNBC.