Ⅲc期卵巢癌淋巴结转移对患者预后的影响

赵睿; 马玲

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Ⅲc期卵巢癌淋巴结转移对患者预后的影响

赵睿 , 马玲

文章导航 > 蚌埠医学院学报 > 2013, 37 > 11: (1408-1409)

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Ⅲc期卵巢癌淋巴结转移对患者预后的影响

赵睿,
马玲^,

1.
蚌埠医学院第一附属医院肿瘤妇科, 安徽蚌埠 233004

作者简介: 赵睿(1987－ ),女,硕士研究生.

通讯作者: 马玲, ML1970222@yahoo.com.cn

基金项目:

Impact of lymphatic metastasis on prognosis of stage Ⅲc ovarian carcinoma

ZHAO Rui,
MA Ling^,

1.
Department of Gynecologic Oncology, The First Affiliated Hospital of Bengbu Medical College, Bengbu Anhui 233004, China

Corresponding author: MA Ling, ML1970222@yahoo.com.cn

摘要: 目的:分析Ⅲc期卵巢癌患者淋巴结转移对预后的影响。方法:回顾性分析2003~2010年Ⅲc期卵巢癌41例,患者均已行规范手术治疗,术后予以足疗程化疗。单纯淋巴结转移者12例,腹腔腹膜种植瘤直径2 cm不考虑淋巴结是否有转移者29例;术后无残留或者残留灶1 cm 25例,术后残留1 cm 16例。结果:随访2~90个月,Ⅲc期卵巢癌患者中,单纯淋巴结转移者的3年和5年生存率分别为83.3%与75.0%,腹腔腹膜种植瘤直径2 cm不考虑淋巴结者为58.6%与37.9%,5年生存率差异有统计学意义(P0.05);术后无残留或残留灶1 cm的患者3年和5年生存率分别为80.0%与56.0%,均高于术后残留1 cm者(P0.05)。结论:单纯淋巴结转移的Ⅲc期卵巢癌患者的预后好于有腹腔腹膜转移的Ⅲc期卵巢癌患者,残留灶大小是影响Ⅲc期卵巢癌患者预后的相关因素。
- 卵巢肿瘤 /
- 淋巴转移 /
- 残余肿瘤 /
- 预后
Abstract: Objective: To investigate the impact of lymph node metastasis on the prognosis of patients with stage Ⅲ c ovarian carcinoma. Methods: Forty-one patients with stage Ⅲc ovarian cancer from 2003 to 2010 were analyzed retrospectively. All the patients had received line specification surgery and enough cycles of postoperative chemotherapy. Twelve cases had simple lymph node metastasis and 29 intra-abdominal peritoneal tumors 2 cm in diameter without or with lymph node metastasis; 25 cases had no postoperative residual or residual tumors 1 cm in size,and 16 had residual tumors 1 cm in size. Results: The follow-up ranged from 2 to 90 months. The 3-year overall survival( OS) and the 5-year OS in patients with simple lymph node metastasis were 83. 3% and 75. 0% respectively; whereas the 3-year and 5-year OS in cases with intra-abdominal peritoneal tumors 2 cm in diameter without or with lymph node metastasis were 58. 6% and 37. 9%,respectively. The 5-year OS was statistically different( P 0. 05); The patients with no postoperative residual or residual tumors 1 cm in size had significantly better outcomes; and their 3-year OS and 5-year OS were 80. 0% and 56. 0% respectively,which were significantly higher than those with residual tumors 1 cm in size( P 0. 05). Conclusions: Patients of stage Ⅲc ovarian carcinoma with simple lymph node metastasis have a better prognosis than those with intra-abdominal peritoneal tumors 2 cm in diameter. The size of residual tumor is the relevant prognostic factor for patients with stage Ⅲc ovarian carcinoma.
- ovarian neoplasms /
- lymphatic metastasis /
- residual tumor /
- prognosis

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Ⅲc期卵巢癌淋巴结转移对患者预后的影响

赵睿
马玲^,

通讯作者: 马玲, ML1970222@yahoo.com.cn

作者简介: 赵睿(1987－ ),女,硕士研究生.

1. 蚌埠医学院第一附属医院肿瘤妇科, 安徽蚌埠 233004

收稿日期: 2012-11-21
网络出版日期: 2013-11-15

基金项目:

关键词:

摘要: 目的:分析Ⅲc期卵巢癌患者淋巴结转移对预后的影响。方法:回顾性分析2003~2010年Ⅲc期卵巢癌41例,患者均已行规范手术治疗,术后予以足疗程化疗。单纯淋巴结转移者12例,腹腔腹膜种植瘤直径2 cm不考虑淋巴结是否有转移者29例;术后无残留或者残留灶1 cm 25例,术后残留1 cm 16例。结果:随访2~90个月,Ⅲc期卵巢癌患者中,单纯淋巴结转移者的3年和5年生存率分别为83.3%与75.0%,腹腔腹膜种植瘤直径2 cm不考虑淋巴结者为58.6%与37.9%,5年生存率差异有统计学意义(P0.05);术后无残留或残留灶1 cm的患者3年和5年生存率分别为80.0%与56.0%,均高于术后残留1 cm者(P0.05)。结论:单纯淋巴结转移的Ⅲc期卵巢癌患者的预后好于有腹腔腹膜转移的Ⅲc期卵巢癌患者,残留灶大小是影响Ⅲc期卵巢癌患者预后的相关因素。

English Abstract

Impact of lymphatic metastasis on prognosis of stage Ⅲc ovarian carcinoma

ZHAO Rui
MA Ling^,

Corresponding author: MA Ling, ML1970222@yahoo.com.cn

1. Department of Gynecologic Oncology, The First Affiliated Hospital of Bengbu Medical College, Bengbu Anhui 233004, China

Received Date: 2012-11-21
Available Online: 2013-11-15

Abstract: Objective: To investigate the impact of lymph node metastasis on the prognosis of patients with stage Ⅲ c ovarian carcinoma. Methods: Forty-one patients with stage Ⅲc ovarian cancer from 2003 to 2010 were analyzed retrospectively. All the patients had received line specification surgery and enough cycles of postoperative chemotherapy. Twelve cases had simple lymph node metastasis and 29 intra-abdominal peritoneal tumors 2 cm in diameter without or with lymph node metastasis; 25 cases had no postoperative residual or residual tumors 1 cm in size,and 16 had residual tumors 1 cm in size. Results: The follow-up ranged from 2 to 90 months. The 3-year overall survival( OS) and the 5-year OS in patients with simple lymph node metastasis were 83. 3% and 75. 0% respectively; whereas the 3-year and 5-year OS in cases with intra-abdominal peritoneal tumors 2 cm in diameter without or with lymph node metastasis were 58. 6% and 37. 9%,respectively. The 5-year OS was statistically different( P 0. 05); The patients with no postoperative residual or residual tumors 1 cm in size had significantly better outcomes; and their 3-year OS and 5-year OS were 80. 0% and 56. 0% respectively,which were significantly higher than those with residual tumors 1 cm in size( P 0. 05). Conclusions: Patients of stage Ⅲc ovarian carcinoma with simple lymph node metastasis have a better prognosis than those with intra-abdominal peritoneal tumors 2 cm in diameter. The size of residual tumor is the relevant prognostic factor for patients with stage Ⅲc ovarian carcinoma.