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视网膜干细胞相关基因的研究进展

栾文斌 项平

引用本文:
Citation:

视网膜干细胞相关基因的研究进展

    作者简介: 栾文斌(1984- ), 男, 硕士研究生.
  • 基金项目:

    安徽省教育厅自然科学研究基金重点项目(KJ2010A241)

  • 摘要: 干细胞是近年生命科学研究的热点, 干细胞研究领域的进步使治疗甚至是治愈某些以前无法治疗的疾病成为可能。视网膜干细胞是存在于视网膜的周边区域-睫状边缘带的具有干细胞特性的细胞。在体外, 视网膜干细胞能分化成光感受器细胞、双极细胞及神经胶质细胞等各种视网膜细胞类型。临床上, 可以用移植视网膜干细胞的方法治疗一些致盲性眼病, 如遗传性视网膜变性、老年性黄斑病变、原发或继发性视网膜变性疾病等, 为此类眼病的治疗开辟了新的途径。本文就视网膜干细胞的生物学特性, 包括培养与鉴定, 分化以及与分化过程有关的基因等研究进展作一综述。
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  • 收稿日期:  2011-02-22
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视网膜干细胞相关基因的研究进展

    作者简介: 栾文斌(1984- ), 男, 硕士研究生.
  • 1. 蚌埠医学院第一附属医院中心实验室, 安徽蚌埠 233004
基金项目:  安徽省教育厅自然科学研究基金重点项目(KJ2010A241)

摘要: 干细胞是近年生命科学研究的热点, 干细胞研究领域的进步使治疗甚至是治愈某些以前无法治疗的疾病成为可能。视网膜干细胞是存在于视网膜的周边区域-睫状边缘带的具有干细胞特性的细胞。在体外, 视网膜干细胞能分化成光感受器细胞、双极细胞及神经胶质细胞等各种视网膜细胞类型。临床上, 可以用移植视网膜干细胞的方法治疗一些致盲性眼病, 如遗传性视网膜变性、老年性黄斑病变、原发或继发性视网膜变性疾病等, 为此类眼病的治疗开辟了新的途径。本文就视网膜干细胞的生物学特性, 包括培养与鉴定, 分化以及与分化过程有关的基因等研究进展作一综述。

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