特发性腹膜后纤维化1例及文献复习
Idiopathic retroperitoneal fibrosis: a case report and literature review
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摘要: 目的: 总结特发性腹膜后纤维化(IRF)的临床特征,提高对其认识。方法: 对1例IRF患者的临床表现、影像学资料进行分析,并复习相关文献。结果: 患者男性,72岁,临床症状主要表现为纳差、腹胀,肾功能损害,彩超、CT、MRI均发现腹膜后多发纤维条索形成。予以双侧上尿路置入D-J输尿管内引流及口服泼尼松后,患者肾功能恢复,症状缓解。结论: IRF起病隐匿,临床表现无特异性,需依靠组织学及影像学检查以确诊;早期应用糖皮质激素治疗效果较好,免疫抑制剂和他莫昔芬的应用尚在探索中,晚期出现器官压迫和梗阻时需手术治疗。Abstract: Objective: To summary the clinical features of idiopathic retroperitoneal fibrosis(IRF).Methods: The clinical features and image manifestation of 1 case with IRF were analyzed retrospectively and the related literatures were reviewed.Results: The clinical features of a 72-year-old male with IRF were poor appetite, abdominal distension and kidney function damage.The multiple fiber cord formation were detected by Colored Doppler,CT and MRI.The patient were treated with D-J tube ureteral drainage in the bilateral upper urinary tract and oral prednisone.The renal function and symptoms of patient recovered and relieved.Conclusions: The initial symptoms and clinical features of IRF are not specific, the histological and imaging examination can contribute to its diagnosis.The effect of early application of glucocorticoid is good and the effects of immunosuppressant and tamoxifen are not confirmed.In late stage, surgery is needed at the time of organ oppression and obstruction.
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Key words:
- retroperitoneal fibrosis /
- diagnosis /
- treatment
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