|
[2] van Lohuizen M,Verbeek S,Scheijen B,et al.Identification of cooperating on cogenes in E mu-myc transgenic mice by provirus yagging[J].Cell,1991,65(5):737-752. |
|
[2]
|
van Lohuizen M,Frasch M,wientjens E,et al.Sequence similarity between the mammalian bmi-1 proto-oncogene and the Drosophila regulatory genes Psc and su(z)2[J].Nature,1991,353(6342):353-355. |
|
[3] Datta S,Hoenerhoff MJ,Bommi P,et al.Bmi-1 cooperates with HRas to transform human mammary epithelial cells via dysregulation of multiple growth-regulatory pathways[J].Cancer Res,2007,67(21):10286-10295. |
|
[4] Silva J,Garcia V,Garcia JM,et al.Circulating Bmi-1mRNA as a possible prognostic factor for advanced breast cancer patients[J].Breast Cancer Res,2007,9(4):R55. |
|
[5] Jacobs JJ,Kieboom K,Marino S,et al.The oneogene and polycomgroup gene bmi-1 regulates cell proliferation and senescence through the ink4a locus[J].Nature,1999,397(6715):164- 168. |
|
[6] van Kemenade FJ,Raaphorst FM,Blokzijl T,et al.Coexpression of BMI-1 and EZI-I 2 polycomb-group proteins is associated with cycling cells and degree of ma lignancy in B-cell non-Hodgkin lymphoma[J].Blood,2001,97(12):3896-3901. |
|
[7] hahana K,Zou Y,Itahana Y,et al.Contrel of the replicativel span of human f ibroblasts by p16 and the polycomb protein Bmi-1[J].Mol Cell Biol,2003,23(1):389-401. |
|
[8] Guo WJ,Zeng MS,Yadav A,et al.Mel-18 acts as a tumor suppresor by repressing Bmi-1 expression and down regulating Akt activin breast cancer cells[J].Cancer Res,2007,67(11):5083-5089. |
|
[9] Sherr CJ.The INK4a /ARF network in tumour suppression[J].Na tёv RMol Cell Biol,2001,2(10):731-737. |
|
[10] Braig M,Lee S,Loddenkemper C,et al.Oncogene-induced seneeenee as an initia-l barrier in lymphoma development[J].Nature,2005,436(7051):660-665. |
|
[11] Dimri GP,Martinez TL,Jacobs JJ,et al.The Bmi-1oncogene induces telomerase act ivity and immortalizes human mammary epithelial cells[J].Caner Res,2002,62(16):4736-4745. |
|
[12] Haga K,Ohno S,Yugawa T,et al.Efficient immortalization of primary human cells by p16INK4a-specific short hairpin RNA or Bmi-1,combined with introduction of hTERT[J].Cancer Sci,2007,98(2):147-154. |
|
[13] Kenney S,Ge JQ,Westphal EM,et al.Gene therapy strategies for treating Epstein-Barr virus-associated lymphomas:comparison of two different Epstein-Barr virusbased vectors[J].Hum Gene Ther,1998,9(8):1131-1141. |
|
[14] Liu S,Dontu G,Mantle ID,et al.Hedgehog signaling and Bmi-1 regulate self-renewal of normal and malignant human mammary stem cells[J].Cancer Res,2006,66(12):6063-6071. |
|
[15] Liu S,Dontu G,Wicha MS.Mammary stem cells,self-renewal pathways,and carcinogensis[J].Breast Cancer Res,2005,7(3):86-95. |
|
[16] Kim RH,Mehrazarin S,Oh JE,et al,Kang MK.Bmi-1 extends the life span of normal human oral keratinocytes by inhibiting the TGF- signaling[J].Exp cell Ress,2010,316(16):2600-2608. |
|
[17] Meng S,Luo M,Sun H,et al.Identification and characterization of Bmi-1-responding element within the human p16 promoter[J].J Bio Chem,2010,285(43):33219-33229. |
|
[18] Park IK,Qian D,Kiel M,et al.Bmi-1 is required of or maintenance of adult self-renewing haematopoietic stem cells[J].Nature,2003,423(2):302-305. |
|
[19] Bruggeman A,Sophia WM,Valk-Lingbeek L,et al.Ink4a and Arf differentially affect cell proliferation and neural stem cell selfrenewal in Bmi-1 deficient mice [J].Genes Devel,2005,19(12):1438-1443. |
|
[20] Glinsky GV,Berezovska O,Glinskii AB.Microarray analysis idenifies a death from cancer signature predicting therapy failure in patients with multiple types of cancer[J].J Clin Invest,2005,115(6):1503-1521. |
|
[21] Dimri GP,Martinez JL,Jacobs JJ,et al.The Bmi-1 oncogene induces telomera se activity and immortalizes human mammary epithelial cells[J].Cancer Res,2002,62(16):4736-4745. |
|
[22] 冯艳,宋立兵,郭宝红,等.Bmi-1 在乳腺癌组织中的表达及意义[J].癌症,2007,26(2):154-157. |
|
[23] Li W,Li Y,Tan Y,et al.Bmi-1 is critical for the proliferation and invasiveness of gastric carcinoma cells[J].Gastroenterol Hepatol,2010,25(3):568-575. |
|
[24] Liu JH,Song LB,Zhang X,et al.Bmi-1 expression predicts prognosis for patients with gastric carcinoma[J].J Surg Oncol,2008,97(3):267-272. |
|
[25] Li DW,Tang HM,Fan JW,et al.Expression level of Bmi-1 oncoprotein is associated with progression and prognosis in colon cancer[J].J Cancer Ress Clin Oncol,2010,136(7):997-1006. |
|
[26] Lee MO,Lee HJ,Kin MA,et al.p16Ink4a suppression of lung adenocarcinoma by Bmi-1 in the presence of p38 activation[J].J Thorac Oncol,2011,6(3):423-431. |
|
[27] Zhang XY,Dong QG,Huang JS,et al.The expression of stem cellrelated indicators as a prognostic factor in human lung adenocarcinoma[J].J Surg Oncol,2010,102(7):856-862. |
|
[28] Vonlanthen S,Heighway J,Ahtermatt HJ.et al.The bmi-l oncoprotein is differentially expressed in non-small cell lung cancer and correlates with INK4A-ARF locus expression[J].B J Cancer,2001,84(10):1372-1376. |
|
[29] Jagani Z,Wiederschain D,Loo A,et al.The polycomb group protein Bmi-1 is essential for the growth of multiple myeloma cells[J].Cancer Res,2010,70(13):5528-5538. |
|
[30] Sawa M,Yamamoto K,Yokozawa T,et al.Bmi-1 is highly expressed in M0-subtype acut emyeloid leukemia [J].Int J Hematol,2005,82(1):42-47. |
|
[31] Mihara K,Chowdhury M,Nakaju N,et al.Bmi-1 is useful as a novel molecular marker for predicting progression of myelodysplastie syndrome and patient prognosis[J].Blood,2006,107(1):305-308. |
|
[32] Zhang F,Sui L,Xin T.Correlations of Bmi-1 expression and telomerase activity in ovarian cancer tissues[J].Exp Oncol,2008,30(1):70-74. |
|
[33] Bhattacharya R,Kwon J,Ali B,et al.Role of hedgehog signaling in ovarian cancer [J].Clin Cancer Res,2008,14(23):7659-7666. |
|
[34] Godlewski J,Nowicki MO,Bronisz A,et al.Targeting of the Bmi-1 oneogene stem cell renewal factor by microRNA-128 inhibits glioma proliferation and self-ren ewa1[J].Cance Res,2008,68(22):9125-9130. |
|
[35] Kozakowski N,Soleiman A,Pammer J.Bmi-1 expression is inversely correlated with the grading of renal clear cell carcinoma[J].Pathol Oncol Res,2008,14(1):9-13. |
|
[36] Song LB,Zeng MS,Liao WT,et al.Bmi-1 is a novel molecular marker of nasopharyngeal carcinoma progression and immortalizes primary human nasopharyngeal epithelial cells[J].Cancer Res, 2006,66(12):6225-6232. |
|
[37] Balasubramanian S,Adhikary G,Eckert RL.The Bmi-1 polycomb protein antagonizes the(－)-epigallocatechin-3-gallate-dependent suppression of skin cancer cell survival[J].Carcinogenesis,2010,31(3):496-503. |
点击查看大图
下载:
