PA、Hs-CRP、CRP与早产儿胎龄和胎膜早破的关系

王素梅; 徐兵; 陈建文

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PA、Hs-CRP、CRP与早产儿胎龄和胎膜早破的关系

王素梅 , 徐兵 , 陈建文

文章导航 > 蚌埠医学院学报 > 2009, 34 > 12: (1078-1080)

引用本文:

Citation:

PA、Hs-CRP、CRP与早产儿胎龄和胎膜早破的关系

1. 蚌埠医学院第一附属医院儿科, 安徽蚌埠 233004;
2. 蚌埠医学院第一附属医院检验科, 安徽蚌埠 233004

作者简介: 王素梅(1966-),女,副主任医师,副教授.

中图分类号: R722

Correlations of serum PA,Hs-CRP,CRP in premature infants with gestational age and premature rupture of fetal membranes

1. Department of Pediatrics, The First Affiliated Hospital of Bengbu Medical College, Bengbu Anhui 233004, China;
2. Department of Clinical Laboratories, The First Affiliated Hospital of Bengbu Medical College, Bengbu Anhui 233004, China
CLC number: R722

摘要: 目的:探讨早产儿血清前白蛋白(PA)、超敏C反应蛋白(Hs-CRP)、C反应蛋白(CRP)水平与早产儿出生时胎龄和有无胎膜早破及胎膜早破时间的关系。方法:对出生48h以内、胎龄及出生史明确的早产儿80例,分别于生后24~48h内检测血清PA、Hs-CRP、CRP水平;同时摘记早产儿的临床相关资料,包括胎龄、有无胎膜早破及胎膜早破时间。结果:在不同出生胎龄(<32周、32~33⁺⁶周、34~36⁺⁶周)的早产儿组间,血清PA、Hs-CRP、CRP水平的差异均无统计学意义(P>0.05)。在无胎膜早破及胎膜早破<6h、6~24h、>24h分娩的4组间,PA浓度的差异均无统计学意义(P>0.05);Hs-CRP、CRP水平的差异有统计学意义(P<0.05~P<0.01),胎膜早破>24h组血清Hs-CRP和CRP均高于其他各组(P<0.05~P<0.01)。结论:早产儿血清PA、Hs-CRP、CRP水平与早产儿的出生胎龄无关;Hs-CRP和CRP水平与胎膜早破时间长短有关,胎膜早破>24h血清Hs-CRP和CRP水平明显增高;PA水平与有无胎膜早破和胎膜早破时间长短均无关。
- 婴儿,早产,疾病 /
- 前白蛋白 /
- 超敏C反应蛋白 /
- C反应蛋白 /
- 孕龄 /
- 胎膜早破
Abstract: Objective: To investigate the correlations of serum prealbumin(PA),highly sensitive C reactive protein(Hs-CRP) and C reactive protein(CRP) in premature infants with the gestational age and premature rupture of membranes.Methods: Serum PA,Hs-CRP and CRP of 80 preterm infants who were born within 48 hours,and had an affirmed gestation age and birth history were detected within 24-48 hours after birth;the relevant clinical data including gestation age,premature rupture of membrane and the time of premature rupture of membrane were recorded.Results: Serum PA,Hs-CRP and CRP in the premature infants with a gestation age of less than 32 weeks,32-33⁺⁶ weeks and 34-36⁺⁶ weeks had no statistical difference(P>0.05).Serum PA levels in cases with no premature rupture of membrane,or the time of membrane rupture less than 6 hours,6-24 hours and more than 24 hours before birth have no statistical difference(P>0.05),while serum Hs-CRP and CRP levels were statistically different(P<0.05 to P<0.01).Serum Hs-CRP and CRP levels in cases with membrane rupture above 24 hours before birth were obviously higher than those in other groups(P<0.05 to P<0.01).Conclusions: Serum PA,Hs-CRP and CRP levels in preterm infants have no correlation with the gestation age.Serum Hs-CRP and CRP levels are related to the premature rupture of membrane and the time of premature rupture of membrane;serum Hs-CRP and CRP levels in cases with membrane rupture above 24 hours before birth increase significantly;serum PA levels are not concerned with the premature rupture of membrane or the time of premature rupture of membrane.
- infant,premature,diseases /
- prealbumin /
- highly sensitive C reactive protein /
- C reactive protein /
- gestational age /
- fetal membranes,premature rupture

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PA、Hs-CRP、CRP与早产儿胎龄和胎膜早破的关系

作者简介: 王素梅(1966-),女,副主任医师,副教授.

1. 蚌埠医学院第一附属医院儿科, 安徽蚌埠 233004;
2. 蚌埠医学院第一附属医院检验科, 安徽蚌埠 233004

收稿日期: 2008-10-28

关键词:

摘要: 目的:探讨早产儿血清前白蛋白(PA)、超敏C反应蛋白(Hs-CRP)、C反应蛋白(CRP)水平与早产儿出生时胎龄和有无胎膜早破及胎膜早破时间的关系。方法:对出生48h以内、胎龄及出生史明确的早产儿80例,分别于生后24~48h内检测血清PA、Hs-CRP、CRP水平;同时摘记早产儿的临床相关资料,包括胎龄、有无胎膜早破及胎膜早破时间。结果:在不同出生胎龄(<32周、32~33⁺⁶周、34~36⁺⁶周)的早产儿组间,血清PA、Hs-CRP、CRP水平的差异均无统计学意义(P>0.05)。在无胎膜早破及胎膜早破<6h、6~24h、>24h分娩的4组间,PA浓度的差异均无统计学意义(P>0.05);Hs-CRP、CRP水平的差异有统计学意义(P<0.05~P<0.01),胎膜早破>24h组血清Hs-CRP和CRP均高于其他各组(P<0.05~P<0.01)。结论:早产儿血清PA、Hs-CRP、CRP水平与早产儿的出生胎龄无关;Hs-CRP和CRP水平与胎膜早破时间长短有关,胎膜早破>24h血清Hs-CRP和CRP水平明显增高;PA水平与有无胎膜早破和胎膜早破时间长短均无关。

English Abstract

Correlations of serum PA,Hs-CRP,CRP in premature infants with gestational age and premature rupture of fetal membranes

1. Department of Pediatrics, The First Affiliated Hospital of Bengbu Medical College, Bengbu Anhui 233004, China;
2. Department of Clinical Laboratories, The First Affiliated Hospital of Bengbu Medical College, Bengbu Anhui 233004, China

Received Date: 2008-10-28

Abstract: Objective: To investigate the correlations of serum prealbumin(PA),highly sensitive C reactive protein(Hs-CRP) and C reactive protein(CRP) in premature infants with the gestational age and premature rupture of membranes.Methods: Serum PA,Hs-CRP and CRP of 80 preterm infants who were born within 48 hours,and had an affirmed gestation age and birth history were detected within 24-48 hours after birth;the relevant clinical data including gestation age,premature rupture of membrane and the time of premature rupture of membrane were recorded.Results: Serum PA,Hs-CRP and CRP in the premature infants with a gestation age of less than 32 weeks,32-33⁺⁶ weeks and 34-36⁺⁶ weeks had no statistical difference(P>0.05).Serum PA levels in cases with no premature rupture of membrane,or the time of membrane rupture less than 6 hours,6-24 hours and more than 24 hours before birth have no statistical difference(P>0.05),while serum Hs-CRP and CRP levels were statistically different(P<0.05 to P<0.01).Serum Hs-CRP and CRP levels in cases with membrane rupture above 24 hours before birth were obviously higher than those in other groups(P<0.05 to P<0.01).Conclusions: Serum PA,Hs-CRP and CRP levels in preterm infants have no correlation with the gestation age.Serum Hs-CRP and CRP levels are related to the premature rupture of membrane and the time of premature rupture of membrane;serum Hs-CRP and CRP levels in cases with membrane rupture above 24 hours before birth increase significantly;serum PA levels are not concerned with the premature rupture of membrane or the time of premature rupture of membrane.