靶控输注咪达唑仑对硬膜外麻醉寒战的影响

凌云志; 梁启胜; 李晓红; 禹莉

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靶控输注咪达唑仑对硬膜外麻醉寒战的影响

凌云志 , 梁启胜 , 李晓红 , 禹莉

文章导航 > 蚌埠医学院学报 > 2010, 35 > 8: (776-778,781)

引用本文:

Citation:

靶控输注咪达唑仑对硬膜外麻醉寒战的影响

1. 蚌埠医学院第一附属医院麻醉科, 安徽蚌埠 233004;
2. 蚌埠医学院临床检验诊断学教研室, 安徽蚌埠 233030

作者简介: 凌云志(1977-),男,硕士,住院医师.

中图分类号: R364.6

Clinical observation of target-controlled infusion with midazolam for shivering in patients undergoing epidural anesthesia

1. Department of Anesthesiology, The First Affiliated Hospital of Bengbu Medical College, Bengbu Anhui 233004;
2. Department of Clinical Laboratory Science, Bengbu Medical College, Bengbu Anhui 233030, China
CLC number: R364.6

摘要: 目的:观察靶控输注(target controlled infusion,TCI)咪达唑仑对硬膜外麻醉寒战的影响。方法:选择硬膜外麻醉下行下腹部手术发生寒战患者40例,随机分成2组,每组20例。寒战出现后2min内,A组TCI咪达唑仑,B组静脉注射芬氟合剂。监测2组患者术前和术中生命体征的变化,警觉/镇静(OAA/S)观察评分法监测镇静程度,评价治疗寒战的疗效。结果:2组患者术中平均动脉压(MAP)、心率(HR)、脉搏血氧饱和度(SpO₂)总体处于平稳状态,均在正常范围内。2组患者MAP、HR的监测值在给药后各时间点差异均无统计学意义(P>0.05),而SpO₂监测值给药后10min差异有统计学意义(P<0.01)。A组治疗寒战有效率明显大于B组(P<0.01)。2组给药后各时间点镇静评分差异均有统计学意义(P<0.05~P<0.01)。其中A组OAA/S评分维持在2~3分,B组OAA/S评分在5min和10min时维持在3~4分,随着时间的延长,镇静程度减弱。结论:TCI咪达唑仑减轻硬膜外麻醉寒战安全、方便、有效。
- 寒战 /
- 麻醉,硬膜外 /
- 靶控输注 /
- 咪达唑仑
Abstract: Objective: To investigate the effect of target controlled infusion (TCI) with midazolam for shivering in patients undergoing epidural anesthesia.Methods: Forty patients undergoing lower-abdominal operation with shivering were randomly divided into two equal groups (n=20,respectively):group A combined TCI with midazolam,while group B combined intravenous injection with droperidol-fentany.The changes of vital sign were monitored before and during operation.The sedation degree was evaluated by the Observer's Assessment of Alertness/Sedation (OAA/S) Scale.The therapeutic effect of shivering was estimated.Results: The numbers of mean arterial pressure (MAP),heart rate (HR) and pulse oxygen saturation (SpO₂) were stable during the operation between two groups.They were within normal limits.Although the numbers of MAP and HR in group B after administration were lower than preoperative,the patients need not be treated.There were no significant differences in MAP and HR at different periods after the administration between two groups (P>0.05).While there was significant difference in SpO₂ at minite 10 (P<0.01).The effective power of treating shiver of group A was better than group B (P<0.01).There was significant difference in sedation scale at different periods after the administration between two groups (P<0.05 to P<0.01).The OAA/S scale in group A maintained 2 to 3.The scales were 3 to 4 in group B at minite 5 and 10.The sedation degree weakened along with time prolonged.Conclusions: TCI with midazolam for shivering in patients undergoing epidural anesthesia is safe and convenient and effective.
- anesthesia,epidural /
- target controlled infusion /
- midazolam /
- shivering

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靶控输注咪达唑仑对硬膜外麻醉寒战的影响

作者简介: 凌云志(1977-),男,硕士,住院医师.

1. 蚌埠医学院第一附属医院麻醉科, 安徽蚌埠 233004;
2. 蚌埠医学院临床检验诊断学教研室, 安徽蚌埠 233030

收稿日期: 2009-12-01

关键词:

摘要: 目的:观察靶控输注(target controlled infusion,TCI)咪达唑仑对硬膜外麻醉寒战的影响。方法:选择硬膜外麻醉下行下腹部手术发生寒战患者40例,随机分成2组,每组20例。寒战出现后2min内,A组TCI咪达唑仑,B组静脉注射芬氟合剂。监测2组患者术前和术中生命体征的变化,警觉/镇静(OAA/S)观察评分法监测镇静程度,评价治疗寒战的疗效。结果:2组患者术中平均动脉压(MAP)、心率(HR)、脉搏血氧饱和度(SpO₂)总体处于平稳状态,均在正常范围内。2组患者MAP、HR的监测值在给药后各时间点差异均无统计学意义(P>0.05),而SpO₂监测值给药后10min差异有统计学意义(P<0.01)。A组治疗寒战有效率明显大于B组(P<0.01)。2组给药后各时间点镇静评分差异均有统计学意义(P<0.05~P<0.01)。其中A组OAA/S评分维持在2~3分,B组OAA/S评分在5min和10min时维持在3~4分,随着时间的延长,镇静程度减弱。结论:TCI咪达唑仑减轻硬膜外麻醉寒战安全、方便、有效。

English Abstract

Clinical observation of target-controlled infusion with midazolam for shivering in patients undergoing epidural anesthesia

1. Department of Anesthesiology, The First Affiliated Hospital of Bengbu Medical College, Bengbu Anhui 233004;
2. Department of Clinical Laboratory Science, Bengbu Medical College, Bengbu Anhui 233030, China

Received Date: 2009-12-01

Abstract: Objective: To investigate the effect of target controlled infusion (TCI) with midazolam for shivering in patients undergoing epidural anesthesia.Methods: Forty patients undergoing lower-abdominal operation with shivering were randomly divided into two equal groups (n=20,respectively):group A combined TCI with midazolam,while group B combined intravenous injection with droperidol-fentany.The changes of vital sign were monitored before and during operation.The sedation degree was evaluated by the Observer's Assessment of Alertness/Sedation (OAA/S) Scale.The therapeutic effect of shivering was estimated.Results: The numbers of mean arterial pressure (MAP),heart rate (HR) and pulse oxygen saturation (SpO₂) were stable during the operation between two groups.They were within normal limits.Although the numbers of MAP and HR in group B after administration were lower than preoperative,the patients need not be treated.There were no significant differences in MAP and HR at different periods after the administration between two groups (P>0.05).While there was significant difference in SpO₂ at minite 10 (P<0.01).The effective power of treating shiver of group A was better than group B (P<0.01).There was significant difference in sedation scale at different periods after the administration between two groups (P<0.05 to P<0.01).The OAA/S scale in group A maintained 2 to 3.The scales were 3 to 4 in group B at minite 5 and 10.The sedation degree weakened along with time prolonged.Conclusions: TCI with midazolam for shivering in patients undergoing epidural anesthesia is safe and convenient and effective.