[1]
|
ZADINA JE,HACKLER L,GE LJ,et al. A potent and selective endogenous agonist for the mu-opiate receptor[J]. Nature,1997, 386(6624):499. |
[2]
|
DE MARCO R,JANECKA A. Strategies to improve bioavailability and in vivo efficacy of the endogenous opioid peptides endomorphin-1 and endomorphin-2[J]. Curr Top Med Chem, 2015,16(2):141. |
[3]
|
PERLIKOWSKA R,JANECKA A. Bioavailability of endomorphins and the blood-brain barrier-a review[J]. Med Chem,2014,10(1):2. |
[4]
|
COWELL SM,LEE YS,CAIN JP,et al. Explorng Ramachandran and chi space:conformationally constrained amino acids and peptides in the design of bioactive polypeptide ligands[J]. Curr Med Chem,2004,11(21):2785. |
[5]
|
JANECKA A,STANISZEWSKA R,FICHNA J. Endomorphin analogs[J]. Curr Med Chem,2007,14(30):3201. |
[6]
|
WANG CL, GUO C, ZHOU Y, et al. In vitro and in vivo characterization of opioid activities of C-terminal esterified endomorphin-2 analogs[J]. Peptides,2009,30(9):1697. |
[7]
|
CHAMPION HC,ZADINA JE,KASTIN AJ,et al. Endomorphin 1 and 2 have vasodepressor activity in the anesthetized mouse[J]. Peptides,1998,19(5):925. |
[8]
|
CHAMPION HC,ZADINA JE,KASTIN AJ,et al. The endogenous mu-opioid receptor agonists endomorphins 1 and 2 have novel hypotensive activity in the rabbit[J]. Biochem Biophys Res Commun,1997,235(3):567. |
[9]
|
CHAMPION HC,ZADINA JE,KASTIN AJ,et al. Endomorphin 1 and 2,endogenous ligands for the mu-opioid receptor,decrease cardiac output, and total peripheral resistance in the rat[J]. Peptides,1997,18(9):1393. |
[10]
|
WU N,HUO XF,CHEN Q,et al. Effects of intracerebroventricular administration of endomorphin-1 on blood pressure in anesthetized rats[J]. Yao Xue Xue Bao,2001,36(10):731. |
[11]
|
LIU J, WU WM, CHE JJ, et al. Endomorphins restored the endothelium-dependent relaxation of the rabbit aorta rings exposed to high D-glucose condition via NO-cGMP pathway[J]. Protein Pept Lett,2006,13(10):1037. |
[12]
|
WANG CL,YU Y,LAI LH,et al. Cardiovascular responses to intrathecal administration of endomorphins in anesthetized rats[J]. Peptides,2007,28(4):871. |
[13]
|
PUGSLEY MK. The diverse molecular mechanisms responsible for the actions of opioids on the cardiovascular system[J]. Pharmacol Ther,2002,93(1):51. |
[14]
|
KWOK EH,DUN NJ. Endomorphins decrease heart rate and blood pressure possibly by activating vagal afferents in anesthetized rats[J]. Brain Res,1998,803(1/2):204. |
[15]
|
VIARD E,SAPRU HN. Endomorphin-2 in the medial NTS attenuates the responses to baroreflex activation[J]. Brain Res,2006(1073/1074):365. |
[16]
|
白三省,陈文生,杨阳,等.μ阿片受体在大鼠腹主动脉、心脏和肾脏的分布和定位[J].中国体外循环杂志,2012,10(4):239. |
[17]
|
CHAMPION HC,BIVALACQUA TJ,FRIEDMAN DE,et al. Nitric oxide release mediates vasodilator responses to endomorphin 1 but not nociceptin/OFQ in the hindquarters vascular bed of the rat[J]. Peptides,1998,19(9):1595. |
[18]
|
QI YM,YANG DJ,DUAN X,et al. Endomorphins inhibit contractile responses of rat thoracic aorta rings induced by phenylephrine and angiotensin Ⅱ in vitro[J]. Acta Pharmacol Sin,2002,23(1):40. |
[19]
|
CHEN ZC,SHIEH JP,CHUNG HH,et al. Activation of peripheral opioid μ-receptors in blood vessel may lower blood pressure in spontaneously hypertensive rats[J]. Pharmacology, 2011, 87(5/6):257. |
[20]
|
DAI X, SONG HJ, CUI SG, et al. The stimulative effects of endogenous opioids on endothelial cell proliferation,migration and angiogenesis in vitro[J]. Eur J Pharmacol,2010,628(1/3):42. |
[21]
|
LIU J,WEI S,TIAN L,et al. Effects of endomorphins on human umbilical vein endothelial cells under high glucose[J]. Peptides, 2011,32(1):86. |
[22]
|
FENG Y,ZHAO QY,CHEN Q,et al. Vasorelaxant responses to endomorphin 1[psi] and endomorphin 2[psi], analogues of endomorphins,in rat aorta rings[J]. Pharmazie,2005,60(11):851. |
[23]
|
ZHAO QY, CHEN Q, FENG Y, et al.[TIC4] endomorphins, analogues of endomorphins, have significantly enhanced vasorelaxant effects in rat aorta rings[J]. Protein Pept Lett,2005, 12(4):323. |
[24]
|
YU Y, WANG CL, CUI Y, et al. C-terminal amide to alcohol conversion changes the cardiovascular effects of endomorphins in anesthetized rats[J]. Peptides,2006,27(1):136. |
[25]
|
LIU H,YANG Y,XIN R,et al. Differential cardiovascular effects of synthetic peptides derived from endomorphin-1 in anesthetized rats[J]. Peptides,2008,29(6):1048. |
[26]
|
TANAKA K, KERSTEN JR, RIESS ML. Opioid-induced cardioprotection[J]. Curr Pharm Des,2014,20(36):5696. |
[27]
|
LI R, WONG GT, WONG TM, et al. Intrathecal morphine preconditioning induces cardioprotection via activation of delta, kappa,and mu opioid receptors in rats[J]. Anesth Analg,2009, 108(1):23. |
[28]
|
MASLOV LN,NARYZHNAIA NV,TSIBULNIKOV SY,et al. Role of endogenous opioid peptides in the infarct size-limiting effect of adaptation to chronic continuous hypoxia[J]. Life Sci,2013,93(9/11):373. |
[29]
|
宗巧凤,张冠军,于影,等.内吗啡肽-1后处理对大鼠心肌缺血再灌注损伤的作用[J].蚌埠医学院学报,2014,39(10):1317. |
[30]
|
BROWN DA, SABBAH HN, SHAIKH SR. Mitochondrial inner membrane lipids and proteins as targets for decreasing cardiac ischemia/reperfusion injury[J]. Pharmacol Ther,2013,140(3):258. |
[31]
|
NERI M,FINESCHI V,DI PAOLO M,et al. Cardiac oxidative stress and inflammatory cytokines response after myocardial infarction[J]. Curr Vasc Pharmacol,2015,13(1):26. |
[32]
|
GONG P,CHEN FX,ZHAO Q,et al. The oxidation metabolites of endomorphin 1 and its fragments induced by free radicals[J]. J Pept Sci,2009,15(5):337. |
[33]
|
FENG Y,LU Y,LIN X,et al. Endomorphins and morphine limit anoxia-reoxygenation-induced brain mitochondrial dysfunction in the mouse[J]. Life Sci,2008,82(13/14):752. |