复发性脑实质内出血危险因素研究
Investigation of the risk factors of the recurrent intracerebral hemorrhage
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摘要: 目的:研究复发性脑实质内出血的危险因素。方法:将脑出血患者260例的年龄、性别、高血压、高脂血症、糖尿病及影像学等纳入研究范围,并记录患者第一次脑出血发生年龄及时间、间隔发生的时间、出血量、部位、发病因素和入院时GCS评分。结果:260例中有62例(23.8%)发生再出血,主要为基底核出血(62.9%),时间间隔为3 d至118个月。舒张压>95 mmHg者脑出血复发率为44%,舒张压在临界值以下者为20%,差异有统计学意义(P<0.01)。结论:舒张压控制越好,脑出血复发的危险性越低。Abstract: Objective: To investigate the risk factors of the recurrent intracerebral hemorrhage.Methods: The data of the age,gender,hypertension,hyperlipidemia,diabetes and imaging in 260 patients with cerebral hemorrhage were investigated.The general condition,risk factors,the first cerebral hemorrhage age and time,recurrence interval time,amount and location of bleeding,and pathogenesis of patients were recorded.The disease condition and state of consciousness of patients at admission were evaluated using GCS scare.Results: Among 260 cases,the rebleeding occurred in 62 cases(23.8%),the location and interval time of which were in basal ganglia(62.9%) and 3 days to 118 months,respectively.The recurrence rate of cerebral hemorrhage was 44% when the diastolic blood pressure was more than 95 mmHg.When the diastolic blood pressure was less than the critical value,the recurrence rate of cerebral hemorrhage was 20%,and the difference of which was not statistically significant(P<0.01).Conclusions: The better the diastolic blood pressure controls,the lower the risk of the recurrence of cerebral hemorrhage is.
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Key words:
- cerebral hemorrhage /
- risk factor /
- blood pressure
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[1] TOSHIO I,SHIGERU I,TATSUFUMI N.Contribution of deep microbleeds to stroke recurrence:differences between patients with past deep intracerebral hemorrhages and lacunar infarctions[J].J Stroke Cerebrovasc Dis,2015,24(8):1855. [2] GREENBERG SM,ENG JA,NING M,et al.Hemorrhage burden predicts recurrent intracerebral hemorrhage after lobar hemorrhage[J].Stroke,2004,35(6):1415. [3] JEON SB,KANG DW,CHO AH,et al.Initial microbleeds at MR imaging can predict recurrent intracerebral hemorrhage[J].J Neurol,2007,254(4):508. [4] IMAIZUMI T,INAMURA S,KOHAMA I,et al.Antithrombotic drug uses and deep intracerebral hemorrhages in stroke patients with deep cerebral microbleeds[J].J Stroke Cerebrovasc Dis,2013,22(6):869. [5] SUEDA Y,NAKA H,OHTSUKI T,et al.Positional relationship between recurrent intracerebral hemorrhage/lacunar infarction and previously detected microbleeds[J].Am J Neuroradiol,2010,31(8):1498. [6] MISRA UK,KALITA J,SOMARAJAN BI.Recurrent intracerebral hemorrhage in patients with hypertension is associated with APOE gene polymorphism:a preliminary study[J].J Stroke Cerebrovasc Dis,2013,22(6):758. [7] KIM KH,KIM HD,KIM YZ.Comparisons of 30-day mortalities and 90-day functional recoveries after first and recurrent primary intracerebral hemorrhage attacks:a multiple-institute retrospective study[J].World Neurosurg,2013,79(3):489. [8] IMAIZUMI T,INAMURA S,KOHAMA I,et al.Antithrombotic drug uses and deep intracerebral hemorrhages in stroke patients with deep cerebral microbleeds[J].J Stroke Cerebrovasc Dis,2013,22(6):869. [9] RUTTEN-JACOBS LC,MAAIJWEE NA,ARNTZ RM,et al.Clinical characteristics and outcome of intracerebral hemorrhage in young adults[J].J Neurol,2014,261(11):2143. [10] ROBINSON R.News from the AAN annual meeting:prehypertension found to increase the risk of recurrent intracerebral hemorrhage[J].Neurol Today,2015,15(11):1. [11] HUHTAKANGAS J,LÖPPÖNEN P,TETRI S,et al.Predictors for recurrent primary intracerebral hemorrhage a retrospective population-based study[J].Stroke,2013,44(3):585.
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