密封结肠灌洗在左半结肠癌并急性肠梗阻Ⅰ期切除吻合术中的应用

张剑宝; 张碧红; 庄哲宏; 谭诗成; 张冬辉

doi:10.13898/j.cnki.issn.1000-2200.2016.12.028

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密封结肠灌洗在左半结肠癌并急性肠梗阻Ⅰ期切除吻合术中的应用

张剑宝 , 张碧红 , 庄哲宏 , 谭诗成 , 张冬辉

文章导航 > 蚌埠医学院学报 > 2016, 41 > 12: (1626-1628)

引用本文:

Citation:

密封结肠灌洗在左半结肠癌并急性肠梗阻Ⅰ期切除吻合术中的应用

1. 广东省深圳市福田区人民医院普外科, 518000;
2. 广东省深圳市松岗人民医院普外科, 518000

作者简介: 张剑宝(1981-),男,主治医师.

中图分类号: R735.35

The clinical application of seal colonic lavage in one-stage resection and anastomosis for left semicolonic carcinoma complicated with acute intestinal obstruction

1. Department of General Surgery, The Futian District People's Hospital of Shenzhen, Shenzhen Guangdong 518000;
2. Department of General Surgery, The Songgang District People's Hospital of Shenzhen, Shenzhen Guangdong 518000, China
CLC number: R735.35

摘要: 目的：探讨密封结肠清洁灌洗在左半结肠癌并急性梗阻Ⅰ期切除吻合术中的临床应用价值。方法：采用前瞻性研究方法，选取左半结肠癌并急性梗阻患者63例，随机分为2组，均给予Ⅰ期切除吻合术，对照组31例术中常规解除梗阻，观察组32例则采用全结肠密封清洁灌洗术；对比2组的临床疗效、术后并发症及血清炎性指标。结果：观察组患者的临床总有效率高于对照组（P<0.05）；2组并发症发生率差异无统计学意义（P>0.05）。2组患者治疗前血清白细胞介素-6和肿瘤坏死因子-α水平差异均无统计学意义（P>0.05）；观察组患者治疗后的血清白细胞介素-6和肿瘤坏死因子-α水平均明显低于对照组（P<0.01）。结论：左半结肠癌并急性梗阻Ⅰ期切除吻合术中进行密封结肠清洁灌洗可彻底清除肠腔内病原体和污物，利于控制术后感染，提高患者恢复水平。
- 结肠肿瘤 /
- 肠梗阻 /
- 结肠灌洗术 /
- 吻合术
Abstract: Objective: To explore the clinical application of seal colonic lavage in one-stage resection and anastomosis for left semicolonic carcinoma complicated with acute intestinal obstruction.Methods: Sixty-three patients with left semicolonic carcinoma complicated with acute intestinal obstruction were randomly divided into the control group(31 cases) and observation group(32 cases),and treated with one-stage resection and anastomosis.The obstruction in control group and observation group were removed with conventional method and seal colonic lavage,respectively.The clinical effect,complication and serum inflammatory indictor between two groups were compared.Results: The clinical total effective rate in observation group was higher than that in control group(P<0.05),and the difference of the incidence rate of the complication between two groups was not statistically significant(P>0.05).The differences of the levels of IL-6 and TNF-α between two groups before treatment were not statistically significant(P>0.05).The levels of IL-6 and TNF-α in observation group after treatment were significantly lower than those in control group(P<0.01).Conclusions: The seal colonic lavage in one-stage resection and anastomosis for left semicolonic carcinoma complicated with acute intestinal obstruction can completely clear the pathogen and contaminant in enteric cavity,which is benefit to control the postoperative infection and improve the recovery of patients.
- colonic neoplasms /
- intestinal obstruction /
- colonic lavage /
- anastomosis

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密封结肠灌洗在左半结肠癌并急性肠梗阻Ⅰ期切除吻合术中的应用

作者简介: 张剑宝(1981-),男,主治医师.

1. 广东省深圳市福田区人民医院普外科, 518000;
2. 广东省深圳市松岗人民医院普外科, 518000

收稿日期: 2014-10-25

关键词:

摘要: 目的：探讨密封结肠清洁灌洗在左半结肠癌并急性梗阻Ⅰ期切除吻合术中的临床应用价值。方法：采用前瞻性研究方法，选取左半结肠癌并急性梗阻患者63例，随机分为2组，均给予Ⅰ期切除吻合术，对照组31例术中常规解除梗阻，观察组32例则采用全结肠密封清洁灌洗术；对比2组的临床疗效、术后并发症及血清炎性指标。结果：观察组患者的临床总有效率高于对照组（P<0.05）；2组并发症发生率差异无统计学意义（P>0.05）。2组患者治疗前血清白细胞介素-6和肿瘤坏死因子-α水平差异均无统计学意义（P>0.05）；观察组患者治疗后的血清白细胞介素-6和肿瘤坏死因子-α水平均明显低于对照组（P<0.01）。结论：左半结肠癌并急性梗阻Ⅰ期切除吻合术中进行密封结肠清洁灌洗可彻底清除肠腔内病原体和污物，利于控制术后感染，提高患者恢复水平。

English Abstract

The clinical application of seal colonic lavage in one-stage resection and anastomosis for left semicolonic carcinoma complicated with acute intestinal obstruction

1. Department of General Surgery, The Futian District People's Hospital of Shenzhen, Shenzhen Guangdong 518000;
2. Department of General Surgery, The Songgang District People's Hospital of Shenzhen, Shenzhen Guangdong 518000, China

Received Date: 2014-10-25

Abstract: Objective: To explore the clinical application of seal colonic lavage in one-stage resection and anastomosis for left semicolonic carcinoma complicated with acute intestinal obstruction.Methods: Sixty-three patients with left semicolonic carcinoma complicated with acute intestinal obstruction were randomly divided into the control group(31 cases) and observation group(32 cases),and treated with one-stage resection and anastomosis.The obstruction in control group and observation group were removed with conventional method and seal colonic lavage,respectively.The clinical effect,complication and serum inflammatory indictor between two groups were compared.Results: The clinical total effective rate in observation group was higher than that in control group(P<0.05),and the difference of the incidence rate of the complication between two groups was not statistically significant(P>0.05).The differences of the levels of IL-6 and TNF-α between two groups before treatment were not statistically significant(P>0.05).The levels of IL-6 and TNF-α in observation group after treatment were significantly lower than those in control group(P<0.01).Conclusions: The seal colonic lavage in one-stage resection and anastomosis for left semicolonic carcinoma complicated with acute intestinal obstruction can completely clear the pathogen and contaminant in enteric cavity,which is benefit to control the postoperative infection and improve the recovery of patients.