• 中国科技论文统计源期刊
  • 中国科技核心期刊
  • 中国高校优秀期刊
  • 安徽省优秀科技期刊

留言板

尊敬的读者、作者、审稿人, 关于本刊的投稿、审稿、编辑和出版的任何问题, 您可以本页添加留言。我们将尽快给您答复。谢谢您的支持!

姓名
邮箱
手机号码
标题
留言内容
验证码

颅内静脉窦血栓形成80例临床分析

李玉玉 ,  钱伟东

downloadPDF
文章导航 > 蚌埠医学院学报  > 2017,  42 > 3: (309-312,316)  
引用本文:
shu
Citation:
shu

颅内静脉窦血栓形成80例临床分析

  • 蚌埠医学院第一附属医院 神经内科, 安徽 蚌埠 233004

    • 作者简介: 李玉玉(1989-),女,硕士,住院医师.

  • 中图分类号: R743

Clinical analysis of the cerebral venous sinus thrombosis in 80 cases

  • Department of Neurology, The First Affiliated Hospital of Bengbu Medical College, Bengbu Anhui 233004, China

  • CLC number: R743

  • 摘要: 目的：探讨颅内静脉窦血栓形成（CVST）的临床特征及影像学表现。方法：回顾性分析80例CVST病人临床特征及影像学表现。结果：急性起病（<1周）38例，亚急性起病（1周至1个月）31 例，慢性起病（>1个月）11例。以头痛为首发症状67例。病变累及单个静脉窦32例，累及多个静脉窦48例。头颅CT平扫直接征象显示率15.00%，间接征象显示率21.25%。头颅MRI/MRV阳性率100%。72例予以低分子肝素钙凝治疗，有效率85.00%，复发率1.25%。结论：CVST多见于中青年，起病形式多样，病因复杂，感染、产褥相关及口服避孕药是最常见的病因。头痛是最多见的症状及首发症状，临床症状各异，缺乏特异性，临床症状结合MRI/MRV可明确诊断，抗凝治疗效果明显，预后良好。
    Abstract: Objective:To investigate the clinical manifestations and imaging features of cerebral venous sinus thrombosis(CVST).Methods:The clinical manifestations and imaging features of CVST in 80 cases were retrospectively analyzed.Results:Among 80 patients diagnosed by CVST,acute onset(<1 week) in 38 cases,subacute onset(1 week to 1 month) in 31 cases and chronic onset(>1 month) in 11 cases were identified.Headache was the first symptom.Thirty-two cases involved in single venous sinus,and 48 cases involved in multiple sinuses.The display rates of direct sign and indirect sign in brain CT were 15.00% and 21.25%,respectively.The positive rate of brain MRI/MRV was 100%.Seventy-two cases were treated with low molecular weight heparin calcium,the effective rate was 85.00%,and recurrence rate was 1.25%.Conclusions:CVST often occures in young people and middle-aged,which has various types of onset and complex causes.Infection,puerperal and oral contraceptive are the most common causes.Headache is the most common and first symptom.The clinical symptom of CVST lacks the specificity,and the clinical symptoms combined with brain MRI/MRV can definitely diagnose.Anticoagulation effect is obvious,and the prognosis is good.
  • [1] SAPOSNIK G,BARINAGARREMENTERIA F,BROWN RD JR, et al. Diagnosis and management of cerebral venous thrombosis:a statement for healthcare professionals from the American Heart Association/American Stroke Association[J]. Stroke,2011,42(4):1158.
    [2] JALILI M,GHOURCHIAN S,SHAHIDI GA,et al. A study of factors associated with cerebral venous thrombosis[J]. Neurol Sci,2013,34(3):321.
    [3] COUTINHO JM, ZUURBIER SM, ARAMIDEH M, et al. The incidence of cerebral venous thrombosis:a cross-sectional study[J]. Stroke,2012,43(12):3375.
    [4] BORHANI HAGHIGHI A,EDGELL RC,CRUZ-FLORES S,et al. Mortality of cerebral venous-sinus thrombosis in a large national sample[J]. Stroke,2012,43(1):262.
    [5] FERRO JM, BACELAR-NICOLAU H, RODRIGUES T, et al. Risk score to predict the outcome of patients with cerebral vein and dural sinus thrombosis[J]. Cerebrovasc Dis,2009,28(1):39.
    [6] EINHAUPL K,STAM J,BOUSSER MG,et al. EFNS guideline on the treatment of cerebral venous and thrombosis in adult patients[J]. Eur J Neurol,2010,17(10):1229.
    [7] IKEJIRI M, SHINDO A, LI Y, et al. Frequent association of thrombophilia in cerebral venous sinus thrombosis[J]. Int J Hematol,2012,95(3):257.
    [8] KHAN M,KAMAL AK,WASAY M. Controversies of treatment modalities for cerebral venous thrombosis[J]. Stroke Res Treat, 2010,2010:956302.
    [9] CONRAD J,PAWLOWSKI M,DOGAN M,et al. Seizures after cerebrovascular events:risk factors and clinical features[J]. Seizure,2013,22(4):275.
    [10] MATHON B,DUCROS A,BRESSON D. Subarachnoid and intra-cerebral hemorrhage in young adults:rare and underdiagnosed[J]. Rev Neurol (Paris),2014,170(2):110.
    [11] KALITA J,GOYAL G,KUMAR P,et al. Intracerebral hemorrhage in young patients from a tertiary neurology center in North India[J]. J Neurol Sci,2014,336(1/2):42.
    [12] PANDA S,PRASHANTHA DK,SHANKAR SR,et al. Localized convexity subarachnoid haemorrhage-a sign of early cerebral venous sinus thrombosis[J]. Eur J Neurol,2010,17(10):1249.
    [13] FERRANTE E,REGNA-GLADIN C,ARPINO I,et al.Pseudo-subarachnoid hemorrhage:a potential imaging pitfall associated with spontaneous intracranial hypotension[J].Clin Neurol Neurosurg,2013,115(11):2324.
    [14] BENABU Y,MARK L,DANIEL S,et al.cerebral venous thrombosis presenting with subarachnoid hemorrhage.case report and review[J].Am J Emerg Med,2009,27(1):96.
    [15] FARRAG A,IRFAN M,GULIANI GK,et al.Occurrence of post-acute recanalization and collateral formation in patients with cerebral venous and sinus thrombosis.A serial venographic study[J].Neurocrit Care,2010,13(3):373.
    [16] LINN J,PFEFFERKORN T,IVANICOVA K,et al.Noncontrast CT in deep cerebral venous thrombosis and sinus thrombosis:comparison of its diagnostic value for both entities[J].AJNR Am J Neuroradiol,2009,30(4):728.
    [17] SAADATNIA M,FATEHI F,BASIRI K,et al.Cerebral venous sinus thrombosis risk factors[J].Int J Stroke,2009,4(2):111.
    [18] QUH,YANG M.Early imaging characteristics of 62 cases of cerebral venous sinus thrombosis[J].Exp Ther Med,2013,5(1):233.
    [19] RIZZO L,CRASTO SG,RUDA R,et al.Cerebral venous thrombosis:role of CT,MRI and MRA in the emergency setting[J].Radiol Med,2010,115(2):313.
    [20] IHN YK,JUNG WS,HWANG SS.The value of T2*-weighted gradient-echo MRI for the diagnosis of cerebral venous sinus thrombosis[J].Clin Imaging,2013,37(3):446.
    [21] SELIM M,CAPLAN LR.Radiological diagnosis of cerebral venous thrombosis[J].Front Neurol Neurosci,2008,23:96.
    [22] DENTALI F,AGENO W.Cerebral vein thrombosis[J].Intern Emerg Med,2010,5(1):27.
    [23] COUTINHO JM,DE BRUIJN SF,DEVEBER G,et al.Anticoagulation for cerebral venous sinus thrombosis[J].Stroke,2012,43(4):e41.
    [24] 毕齐,程焱,董强,等.颅内静脉和静脉窦血栓形成诊治的中国专家共识[J].中华内科杂志,2013,12(52):1088.
  • [1] 陈露 . 彩色多普勒超声在下肢深静脉血栓诊断中的应用价值. 蚌埠医学院学报, 2015, 39(7): 959-960. doi: 10.13898/j.cnki.issn.1000-2200.2015.07.046
    [2] 段鹏飞 . 深静脉血栓形成的分子生物学研究进展. 蚌埠医学院学报, 2004, 29(1): 90-91.
    [3] 司春强 . 兔深静脉血栓形成后内皮细胞凋亡变化. 蚌埠医学院学报, 2007, 32(5): 511-514.
    [4] 陆志前 , 余翔 , 张敏 , 曹镭 , 诸晓艳 . MSCTA、3D-TOFMRA在颅内动脉瘤诊断中的价值. 蚌埠医学院学报, 2016, 41(5): 652-654. doi: 10.13898/j.cnki.issn.1000-2200.2016.05.033
    [5] 高玉芳 , 刘红芬 , 周义双 . 高龄长期卧床患者并发下肢深静脉血栓形成的护理. 蚌埠医学院学报, 2009, 34(2): 171-172.
    [6] 胡锦江 . 肠系膜静脉血栓形成9例误诊分析. 蚌埠医学院学报, 2004, 29(5): 453-454.
    [7] 郭劲松 , 倪良宏 , 唐军建 , 马宁 . 下肢深静脉血栓形成外科治疗分析. 蚌埠医学院学报, 2004, 29(5): 411-412.
    [8] 李素侠 . 下肢骨折术后并发急性深静脉血栓护理. 蚌埠医学院学报, 2007, 32(5): 627-628.
    [9] 王长春 , 韩潞 , 倪良红 . 置管溶栓治疗急性血栓性下腔静脉综合征2例. 蚌埠医学院学报, 2015, 39(7): 934-935. doi: 10.13898/j.cnki.issn.1000-2200.2015.07.035
    [10] 陈景侠 . 静脉血栓栓塞症病人抗凝治疗过程中的风险评估与精准化护理. 蚌埠医学院学报, 2019, 44(1): 116-120. doi: 10.13898/j.cnki.issn.1000-2200.2019.01.033
    [11] 韩梅 , 倪红霞 , 王娜娜 , 胡云芝 . 护理干预在下腔静脉滤器植入围手术期效果评价. 蚌埠医学院学报, 2014, 39(12): 1743-1745.
    [12] 胡云芝 , 倪红霞 , 韩梅 . 低分子肝素钙两种皮下注射法比较. 蚌埠医学院学报, 2010, 35(3): 297-298.
    [13] 朱瑞昉 . 奥扎格雷钠联合低分子肝素钙治疗进展性脑梗死疗效观察. 蚌埠医学院学报, 2012, 36(7): 819-821.
    [14] 郭刚 . 腔隙性脑梗死120例临床与CT、MRI分析. 蚌埠医学院学报, 2006, 31(4): 407-408.
    [15] 苏贺先 , 于振国 , 张少军 , 娄飞云 , 马骏 . 中枢神经系统表皮样囊肿20例CT与MRI诊断. 蚌埠医学院学报, 2005, 30(1): 27-28.
    [16] 周莹 , 周胜利 , 刘雨成 . 原发性中枢神经系统淋巴瘤的CT和MRI表现. 蚌埠医学院学报, 2006, 31(1): 72-74.
    [17] 魏玮琦 . 鼻内镜手术治疗非侵袭性真菌性鼻-鼻窦炎62例疗效分析. 蚌埠医学院学报, 2014, 39(7): 915-917.
    [18] 周金泉 . CT和MRI鉴别诊断良恶性胆道梗阻的临床价值分析. 蚌埠医学院学报, 2016, 41(9): 1240-1242. doi: 10.13898/j.cnki.issn.1000-2200.2016.09.039
    [19] 方美芳 , 王震寰 , 沈龙山 , 单连强 . 胼胝体磁共振弥散张量成像技术参数研究. 蚌埠医学院学报, 2014, 38(1): 34-37.
    [20] 郑维民 , 国志义 , 宋向巍 . 磁共振弥散加权成像在急性脑梗死诊断中的应用. 蚌埠医学院学报, 2009, 34(1): 55-56.
  • 加载中
WeChat 点击查看大图
计量
  • 文章访问数:  4468
  • HTML全文浏览量:  546
  • PDF下载量:  85
  • 被引次数: 0
出版历程
  • 收稿日期:  2016-04-12

颅内静脉窦血栓形成80例临床分析

    作者简介: 李玉玉(1989-),女,硕士,住院医师.
  • 蚌埠医学院第一附属医院 神经内科, 安徽 蚌埠 233004
  • 收稿日期: 2016-04-12

摘要: 目的：探讨颅内静脉窦血栓形成（CVST）的临床特征及影像学表现。方法：回顾性分析80例CVST病人临床特征及影像学表现。结果：急性起病（<1周）38例，亚急性起病（1周至1个月）31 例，慢性起病（>1个月）11例。以头痛为首发症状67例。病变累及单个静脉窦32例，累及多个静脉窦48例。头颅CT平扫直接征象显示率15.00%，间接征象显示率21.25%。头颅MRI/MRV阳性率100%。72例予以低分子肝素钙凝治疗，有效率85.00%，复发率1.25%。结论：CVST多见于中青年，起病形式多样，病因复杂，感染、产褥相关及口服避孕药是最常见的病因。头痛是最多见的症状及首发症状，临床症状各异，缺乏特异性，临床症状结合MRI/MRV可明确诊断，抗凝治疗效果明显，预后良好。

English Abstract

    全文HTML

参考文献 (24)

目录

    /

    返回文章
    返回

    版权所有© 2019《蚌埠医学院学报》编辑部 皖ICP备06000434号-1

    地址：安徽省蚌埠市东海大道2600号 邮编：233030

    电话：0552-3175456 Email：byxb@vip.163.com

    本系统由 北京仁和汇智信息技术有限公司 开发 技术支持： info@rhhz.net   百度统计