缩宫素在剖宫产术中不同用法的临床应用效果分析

李姣

doi:10.13898/j.cnki.issn.1000-2200.2018.02.026

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缩宫素在剖宫产术中不同用法的临床应用效果分析

李姣

文章导航 > 蚌埠医学院学报 > 2018, 43 > 2: (229-231)

引用本文:

Citation:

缩宫素在剖宫产术中不同用法的临床应用效果分析

李姣

湖北省通城县人民医院产科, 437400

作者简介: 李姣(1976-),女,主治医师.

中图分类号: R719.8

Clinical effect analysis of the different uses of oxytocin in cesarean section

LI Jiao

Department of Obstetrics, The People's Hospital of Tongcheng County, Tongcheng Hubei 437400, China
CLC number: R719.8

摘要: 目的：分析缩宫素的不同用法在剖宫产术中预防产后出血的临床效果。方法：选择150例择期行剖宫产的待产妇，按随机数字表法分为A、B和C组，各50例。A组产妇给予子宫肌层注射缩宫素20 U，B组采用子宫肌层注射缩宫素10 U后给予10 U缩宫素静脉滴注，C组经莫非氏管注入缩宫素5 U同时静脉滴注缩宫素10 U。观察3组产妇胎盘剥离时间、术中及术后24 h出血量、不良反应、用药前后其血压及心率变化情况。结果：C组产妇术中及术后24 h平均出血量为（244.1±26.1） mL及（87.4±13.9） mL，胎盘剥离时间为（1.6±0.4） min，均小于A、B组（P<0.01）。3组产妇平均动脉压用药后5 min较用药前有所下降（P<0.01），用药后10 min较用药后5 min有回升（P<0.01）；用药后10 min 3组心率为A组>B组>C组（P<0.05~P<0.01）；3组间不良反应发生率差异无统计学意义（P>0.05）。结论：剖宫产中在娩出胎儿后即给予产妇莫非氏管注入5 U宫缩素，同时给以10 U缩宫素静脉滴注，可以有效降低产妇出血量，减少胎盘剥离时间，且对血压及心率影响较小，值得推广。
- 剖宫产 /
- 产后出血 /
- 缩宫素 /
- 莫非氏管
Abstract: Objective: To analyze the clinical effects of the different uses of oxytocin in preventing the postpartum hemorrhage in cesarean section.Methods: One hundred and fifty puerpera scheduled by cesarean section were divided into the A,B and C groups(50 cases each group)by random number table method.The group A was injected with 20 U oxytocin in myometrium,the group B was intravenously injected with 10 U oxytocin after injecting 10 U oxytocin into myometrium,and the group C was injected with 5 U oxytocin by Murphy's tube combined with intravenous injection with 10 U oxytocin.The placental separation time,blood loss during operation and after 24 hours of operation,adverse effect,blood pressure and heart rate in three groups were observed.Results: The mean blood loss during and after 24 h of operation,and placental separation time in group C were(244.1±26.1)mL,(87.4±13.9) mL and(1.6±0.4)min,respectively,which was less than that in group A and group B(P<0.01).The mean arterial pressure in three groups after 5 min of admission decreased compared with before admission(P<0.01),and began to increase after 10 min of admission(P<0.01).The heart rates in A,B and C groups after 10 min of admission gradually decreased in turn(P<0.05 to P<0.01).The differences of the incidence rates of adverse reaction between three groups were not statistically significant(P>0.05).Conclusions: The 5 U oxytocin injecting by Murphy's tube combined with intravenous injection with 10 U oxytocin can effectively reduce the blood loss and placental separation time,which has little effect on the blood pressure and heart rate,and is worthy of promotion.
- cesarean section /
- postpartum hemorrhage /
- oxytocin /
- Murphy's tube

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缩宫素在剖宫产术中不同用法的临床应用效果分析

李姣

作者简介: 李姣(1976-),女,主治医师.

湖北省通城县人民医院产科, 437400

收稿日期: 2016-07-20
录用日期: 2017-10-15

关键词:

摘要: 目的：分析缩宫素的不同用法在剖宫产术中预防产后出血的临床效果。方法：选择150例择期行剖宫产的待产妇，按随机数字表法分为A、B和C组，各50例。A组产妇给予子宫肌层注射缩宫素20 U，B组采用子宫肌层注射缩宫素10 U后给予10 U缩宫素静脉滴注，C组经莫非氏管注入缩宫素5 U同时静脉滴注缩宫素10 U。观察3组产妇胎盘剥离时间、术中及术后24 h出血量、不良反应、用药前后其血压及心率变化情况。结果：C组产妇术中及术后24 h平均出血量为（244.1±26.1） mL及（87.4±13.9） mL，胎盘剥离时间为（1.6±0.4） min，均小于A、B组（P<0.01）。3组产妇平均动脉压用药后5 min较用药前有所下降（P<0.01），用药后10 min较用药后5 min有回升（P<0.01）；用药后10 min 3组心率为A组>B组>C组（P<0.05~P<0.01）；3组间不良反应发生率差异无统计学意义（P>0.05）。结论：剖宫产中在娩出胎儿后即给予产妇莫非氏管注入5 U宫缩素，同时给以10 U缩宫素静脉滴注，可以有效降低产妇出血量，减少胎盘剥离时间，且对血压及心率影响较小，值得推广。

English Abstract

Clinical effect analysis of the different uses of oxytocin in cesarean section

LI Jiao

Department of Obstetrics, The People's Hospital of Tongcheng County, Tongcheng Hubei 437400, China

Received Date: 2016-07-20
Accepted Date: 2017-10-15

Abstract: Objective: To analyze the clinical effects of the different uses of oxytocin in preventing the postpartum hemorrhage in cesarean section.Methods: One hundred and fifty puerpera scheduled by cesarean section were divided into the A,B and C groups(50 cases each group)by random number table method.The group A was injected with 20 U oxytocin in myometrium,the group B was intravenously injected with 10 U oxytocin after injecting 10 U oxytocin into myometrium,and the group C was injected with 5 U oxytocin by Murphy's tube combined with intravenous injection with 10 U oxytocin.The placental separation time,blood loss during operation and after 24 hours of operation,adverse effect,blood pressure and heart rate in three groups were observed.Results: The mean blood loss during and after 24 h of operation,and placental separation time in group C were(244.1±26.1)mL,(87.4±13.9) mL and(1.6±0.4)min,respectively,which was less than that in group A and group B(P<0.01).The mean arterial pressure in three groups after 5 min of admission decreased compared with before admission(P<0.01),and began to increase after 10 min of admission(P<0.01).The heart rates in A,B and C groups after 10 min of admission gradually decreased in turn(P<0.05 to P<0.01).The differences of the incidence rates of adverse reaction between three groups were not statistically significant(P>0.05).Conclusions: The 5 U oxytocin injecting by Murphy's tube combined with intravenous injection with 10 U oxytocin can effectively reduce the blood loss and placental separation time,which has little effect on the blood pressure and heart rate,and is worthy of promotion.