内镜全层切除术治疗胃固有肌层肿瘤的临床疗效观察
Clinical effect observation of the endoscopic full-thickness resection in treating gastric muscularis propria tumors
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摘要: 目的:比较内镜全层切除术(endoscopic full-thickness resection,EFR)和开腹手术、腹腔镜手术治疗胃固有肌层肿瘤的效果。方法:选择胃固有肌层肿瘤病人53例,其中31例行EFR治疗(EFR组),12例行开腹手术(开腹手术组),10例行腹腔镜手术(腹腔镜组)。对比分析3组病人手术耗时、术后住院时间、住院总费用、术后并发症、复发率与转移率。结果:3组病人在手术耗时、术后住院时间、住院总费用等方面差异均有统计学意义(P<0.05~P<0.01),两两比较显示EFR组术后住院时间低于开腹手术组(P<0.05),EFR组住院总费用低于开腹手术组和腹腔镜组(P<0.05和P<0.01),开腹手术组明显低于腹腔镜组(P<0.01)。术后3组并发症发生差异无统计学意义(P>0.05),危险度分级差异有统计学意义(P<0.05)。结论:EFR治疗胃固有肌层肿瘤具有创伤小、恢复快、费用低等优点,且安全有效,术后不易复发,值得临床推广。Abstract: Objective: To compare the effects among the endoscopic full-thickness resection(EFR),laparotomy and laparoscopic surgery in treating gastric muscularis propria tumors.Methods: Among patients with gastric muscularis propria tumors,31 cases(EFR group),12 cases(laparotomy group) and 10 cases(laparoscopic group) were treated with EFR,laparotomy and laparoscopic surgery,respectively.The operation time,postoperative hospital stay,general expense,complications,relapse rate and metastatic rate among three groups were compared.Results: There were significant differences in operation time,postoperative hospital stay and general expense among three groups(P<0.05 to P<0.01).The results of pair-wise comparison showed that the postoperative hospital stay in EFR group was shorter than that in laparotomy group(P<0.05),the general expense in EFR group was less than that in other two groups(P<0.05 and P<0.01),and the general expense in laparotomy group was significantly less than that in laparoscopic group(P<0.01).The differences of the complicatiens were not statistically significant(P>0.05).The differences of risk factors grading were statistically significent(P<0.05).Conclusions: EFR in treating gastric muscularis propria tumors is small trauma,rapid recovery,low expense,safe and less recurrence,which is worthy of clinical promotion.
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Key words:
- stomach neoplasms /
- endoscopic full-thickness resection /
- laparoscopy
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