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胎儿肠系膜上动脉(superior mesenteric artery, SMA)与腹主动脉(abdominal aorta, AA)的夹角异常与左侧不典型膈疝、肠旋转不良、中肠扭转、左肾静脉压迫综合征、肠系膜上动脉压迫综合征等畸形密切相关[1-7]。查阅国内外文献可见,目前关于SMA与AA夹角的报道主要关注人群是成人和儿童[3, 8-10],胎儿SMA与AA夹角的研究相对少见,不利于产前检查过程中检出与诊断上述畸形。本研究通过测量进行产检结果正常的胎儿SMA与AA夹角,计算其95%参考值范围,并探讨其与孕周、头围和腹围等参数的相关性和性别间差异,为胎儿期检出上述畸形提供影像学依据。
孕21~41周正常胎儿肠系膜上动脉与腹主动脉夹角的参考值范围研究
Study on the reference range of angle between superior mesenteric artery and abdominal aorta in normal fetuses at 21-41 weeks of gestation
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摘要:
目的测量肠系膜上动脉(SMA)与腹主动脉(AA)的夹角,并计算其95%参考值范围;探索其与胎儿孕周、头围、腹围和股骨长的相关性。 方法按纳入标准入组2021年1-4月于安徽医科大学第四附属医院进行产科超声检查的单胎妊娠孕妇。测量每个胎儿SMA与AA的夹角,并探讨该夹角与胎儿孕龄、头围、腹围和股骨长的相关性。 结果共计260例胎儿被纳入研究,孕21~41周正常胎儿SMA与AA的夹角平均值为(57.75±7.27)°(范围为40.90°~73.60°),95%参考值范围43.50°~72.00°。SMA与AA夹角与胎儿孕龄、头围、腹围和股骨长无相关性(r=0.007、0.025、0.022和0.025,P>0.05)。超声测量孕21~41周胎儿SMA与AA夹角具有很好的可重复性(观察者间95%一致性界限区间外数据点数2.86%,观察者内95%一致性界限区间外数据点数为0.04%)。 结论孕21~41周正常胎儿SMA与AA夹角保持相对稳定,与胎儿孕龄、头围、腹围和股骨长无显著相关性。 -
关键词:
- 正常胎儿 /
- 肠系膜上动脉与腹主动脉夹角
Abstract:ObjectiveTo measure the angle between superior mesenteric artery(SMA) and abdominal aorta(AA)(SMA-AA angle) to calculate its 95% reference value range, and explore its correlation with fetal gestational age(GA), head circumference(HC), abdominal circumference(AC) and femoral length(FL). MethodsThe single pregnancy pregnant women diagnosed by obstetric ultrasound examination in The Fourth Affiliated Hospital of Anhui Medical University from January to April 2021 were selected according to the inclusion criteria.The SMA-AA angle in each fetus was measured, and the correlation of the angle with gestational age, head circumference, abdominal circumference and femur length were investigated. ResultsA total of 260 fetuses were included in the study.The mean value of SMA-AA angle of normal fetuses at 21-41 weeks of gestation was(57.75±7.27)°(range from 40.90° to 73.60°), and the 95% reference range was 43.50°-72.00°.There was no significant correlation between the SMA-AA angle and fetal GA, HC, AC and FL(r=0.007, 0.025, 0.022 and 0.025, respectively, P>0.05).The reproducibility of ultrasound measurement of the SMA-AA angle of normal fetuses at 12-41 weeks of gestation was good(the number of data points outside the interval of 95% agreement of inter-observers was 2.86%, and the number of data points outside the interval of 95% agreement of intraobserver was 0.04%). ConclusionsThe SMA-AA angle in normal fetus at 21-41 weeks of gestation remains relatively stable, and is not significantly correlated with fetal GA, HC, AC and FL. -
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