卵巢浆液性癌54例临床分析

刘丽君; 杜丹丽

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卵巢浆液性癌54例临床分析

刘丽君 , 杜丹丽

文章导航 > 蚌埠医学院学报 > 2014, 38 > 5: (609-612)

引用本文:

Citation:

卵巢浆液性癌54例临床分析

刘丽君¹,
杜丹丽^2, ,

1.
1. 蚌埠医学院研究生部，安徽蚌埠 233030;
2.
2. 蚌埠医学院第一附属医院妇产科，安徽蚌埠 233004

作者简介: 刘丽君(1986-)，女，硕士研究生.

通讯作者: 杜丹丽, dudanli0224@sina.com

基金项目:

Clinical analysis of 54 cases of ovarian serous carcinoma

LIU Lijun¹,
DU Danli^2, ,

1.
1. Department of Oncology,Bengbu Medical College,Bengbu Anhui 233030;
2.
2. Department of Obstetrics and Gynecology,The First Affiliated Hospital of Bengbu Medical College,Bengbu Anhui 233004,China

Corresponding author: DU Danli, dudanli0224@sina.com

摘要: 目的：探讨影响卵巢浆液性癌生存预后的因素。方法：具有完整病历资料的卵巢浆液性癌患者54例，记录患者的年龄、临床表现、临床分期、辅助检查。患者均行手术治疗，其中41例早期患者行分期手术，13例晚期患者行肿瘤细胞减灭术。术后均行辅助化疗，其中化疗疗程6次38例，＜6次16例，并对临床资料进行分析。结果：患者发病年龄高峰在50~59岁17例，最常见的症状是腹痛(43例)、阴道出血(7例)、腹胀(35例)、扪及腹块(15例)。术中冷冻存在漏诊，而单一辅助检查难以确诊，需联合应用。术后化疗6 个疗程的患者生存率高于化疗＜6 个疗程的患者(P0.05)。结论：卵巢癌筛查时应把肿瘤标志物的检测与症状、体征及影像学检查结合起来综合分析；提高术中冷冻的准确性尤为关键；肿瘤细胞减灭术，尽可能达到满意；术后尽量保证患者接受 6 次以上的化疗。
- 卵巢浆液性癌 /
- 早期诊断 /
- 临床分期 /
- 手术 /
- 化疗
Abstract: Objective:To investigate the factors affecting the survival prognosis of patients with ovarian serous carcinoma.Methods:Fifty-four patients with ovarian serous carcinoma were included in the study.The age,clinical manifestation,clinical stage and additional tests of the patients were analyzed.All the patients underwent surgical treatment.Forty-one early-stage cases were performed staging surgeries and 13 advanced cases cytoreductive surgeries.All of them received postoperative adjuvant chemotherapy.Thirty-eight cases received not less than 6 courses of chemotherapy and 16 cases less than 6 courses.Results:The peak age of onset was between 50 and 59,and the most common symptoms were abdominal pain(43 cases),vaginal bleeding(7 cases),abdominal distension(35 cases) and palpable abdominal mass(15 cases).Miss-diagnosis often occurred in intraoperative frozen and it was difficult to make a diagnosis by a single auxiliary examination,so combined examination was necessary.The survival rate of the patients having received not less than 6 courses of postoperative chemotherapy was high than that of patients having received less than 6 courses(P0.05).Conclusions:The screening of ovarian cancer should use a comprehensive analysis combining the detection of tumor markers,symptoms,physical signs and imaging;It is particularly important to improve the accuracy of intraoperative frozen;Effective cytoreductive surgery is essential;The patients should be assured to receive not less than 6 courses of postoperative chemotherapy.
- ovarian serous carcinoma /
- early diagnosis /
- clinical stages /
- operation /
- chemotherapy

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卵巢浆液性癌54例临床分析

刘丽君¹
杜丹丽^2, ,

通讯作者: 杜丹丽, dudanli0224@sina.com

作者简介: 刘丽君(1986-)，女，硕士研究生.

1. 1. 蚌埠医学院研究生部，安徽蚌埠 233030;
2. 2. 蚌埠医学院第一附属医院妇产科，安徽蚌埠 233004

收稿日期: 2013-03-11
网络出版日期: 2014-05-15

基金项目:

关键词:

摘要: 目的：探讨影响卵巢浆液性癌生存预后的因素。方法：具有完整病历资料的卵巢浆液性癌患者54例，记录患者的年龄、临床表现、临床分期、辅助检查。患者均行手术治疗，其中41例早期患者行分期手术，13例晚期患者行肿瘤细胞减灭术。术后均行辅助化疗，其中化疗疗程6次38例，＜6次16例，并对临床资料进行分析。结果：患者发病年龄高峰在50~59岁17例，最常见的症状是腹痛(43例)、阴道出血(7例)、腹胀(35例)、扪及腹块(15例)。术中冷冻存在漏诊，而单一辅助检查难以确诊，需联合应用。术后化疗6 个疗程的患者生存率高于化疗＜6 个疗程的患者(P0.05)。结论：卵巢癌筛查时应把肿瘤标志物的检测与症状、体征及影像学检查结合起来综合分析；提高术中冷冻的准确性尤为关键；肿瘤细胞减灭术，尽可能达到满意；术后尽量保证患者接受 6 次以上的化疗。

English Abstract

Clinical analysis of 54 cases of ovarian serous carcinoma

LIU Lijun¹
DU Danli^2, ,

Corresponding author: DU Danli, dudanli0224@sina.com

1. 1. Department of Oncology,Bengbu Medical College,Bengbu Anhui 233030;
2. 2. Department of Obstetrics and Gynecology,The First Affiliated Hospital of Bengbu Medical College,Bengbu Anhui 233004,China

Received Date: 2013-03-11
Available Online: 2014-05-15

Abstract: Objective:To investigate the factors affecting the survival prognosis of patients with ovarian serous carcinoma.Methods:Fifty-four patients with ovarian serous carcinoma were included in the study.The age,clinical manifestation,clinical stage and additional tests of the patients were analyzed.All the patients underwent surgical treatment.Forty-one early-stage cases were performed staging surgeries and 13 advanced cases cytoreductive surgeries.All of them received postoperative adjuvant chemotherapy.Thirty-eight cases received not less than 6 courses of chemotherapy and 16 cases less than 6 courses.Results:The peak age of onset was between 50 and 59,and the most common symptoms were abdominal pain(43 cases),vaginal bleeding(7 cases),abdominal distension(35 cases) and palpable abdominal mass(15 cases).Miss-diagnosis often occurred in intraoperative frozen and it was difficult to make a diagnosis by a single auxiliary examination,so combined examination was necessary.The survival rate of the patients having received not less than 6 courses of postoperative chemotherapy was high than that of patients having received less than 6 courses(P0.05).Conclusions:The screening of ovarian cancer should use a comprehensive analysis combining the detection of tumor markers,symptoms,physical signs and imaging;It is particularly important to improve the accuracy of intraoperative frozen;Effective cytoreductive surgery is essential;The patients should be assured to receive not less than 6 courses of postoperative chemotherapy.