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Monthly Established in March 1976

Supervisor: The Education Department of Anhui Province

Sponsor: Bengbu Medical College

ISSN1000-2200

CN34-1067/R

Editor: Editorial Board of Journal of Bengbu Medical College

Chief Editor:GAO Huai-quan

Editorial Director:YAO Ren-bin

Publication: Editorial Department of Journal of Bengbu Medical College

Postal code: 26-37

Price: Domestic ¥15.00,Overseas $10.00

Articles in press have been peer-reviewed and accepted, which are not yet assigned to volumes /issues, but are citable by Digital Object Identifier (DOI).
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Expression levels of WWOX and ERK1 in esophageal squamous cell carcinoma, and their clinicopathologic significance
ZHANG Qiong, GAN Huai-yong, WU Shi-wu
2020, 45(10): 1313-1316.   doi: 10.13898/j.cnki.issn.1000-2200.2020.10.001
[Abstract](43) [FullText HTML](25) [PDF 1358KB](9)
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ObjectiveTo explore the expression levels of WW domain-containing oxidoreductase(WWOX) and extracellular signal regulated protein kinase 1(ERK1) in esophageal squamous cell carcinoma(ESCC), and their correlations with the clinical characteristics.MethodsThe expression levels of WWOX and ERK1 protein in 150 specimens of ESCC and 80 normal esophageal mucosa tissues were examined using EliVisionTM plus immunohistochemistry.ResultsThe positive rates of WWOX and ERK1 protein in ESCC tissues and normal esophageal tissues were 46.0% & 58.7% and 85.0% & 42.5%, respectively, and the differences of those between two groups were statistically significant(P < 0.05).The positive rate of WWOX protein expression was negatively correlated with the positive rate of ERK1 protein in ESCC tissues(P < 0.01).The differences of the positive expression rates of WWOX and ERK1 protein in ESCC patients with different tumor tissue invasion depth, TNM stage and lymph node metastasis were statistically significant(P < 0.05 to P < 0.01).The results of survival analysis showed that the survival time of patients with positive WWOX expression was higher than that of patients with negative WWOX expression(P < 0.05).The results of multivariate regression analysis showed that the positive WWOX and ERK1 protein expression and TNM stage were the independent influencing factors of postoperative survival of ESCC patients(P < 0.05 to P < 0.01).ConclusionsThe abnormal expression of WWOX and ERK1 may be involved in the occurrence, progression and metastasis of ESCC.The combined detection of WWOX and ERK1 in early stage has an important role in predicting the progression and prognosis of ESCC.
Comparison of therapeutic effect of biliary stent combined with 125I particle implantation and palliative surgery in the treatment of advanced cholangiocarcinoma
ZHOU Lei, PANG Qing, WANG Yong, MAN Zhong-ran, JIN Hao, TAN Yi, LIU Hui-chun
2020, 45(10): 1317-1321.   doi: 10.13898/j.cnki.issn.1000-2200.2020.10.002
[Abstract](44) [FullText HTML](15) [PDF 1181KB](0)
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ObjectiveTo compare the efficacy of self-expanding metal stent combined with catheter loaded 125I particle (SEMS-CL-125I) and palliative surgery (PS) in the treatment of advanced extrahepatic cholangiocarcinoma (EHCC).MethodsPatients with advanced EHCC treated with SEMS-CL-125I (SEMS-CL-125I group, n=67) or PS (PS group, n 34) were selected.The postoperative complications, hospitalization time, hospitalization expenses and overall survival rate (OS) between the two groups were compared.ResultsCompared with that before operation, the levels of TBIL, ALT and AST in the two groups decreased at 1, 3 and 6 months after operation, while ALB increased (P < 0.05).The level of ALB in SEMS-CL-125I group was significantly higher than that in PS group at 1 month after operation (P < 0.05).There was no significant difference in postoperative complications between the two groups (P>0.05).Compared with PS group, The hospitalization time, hospitalization expenses and OS in SEMS-CL-125I group were significantly shorter than those in PS group (P < 0.01), and OS was significantly improved (P < 0.05).Preoperative TBIL, CA19-9, ALB and treatment method were the main factors related to postoperative OS.ConclusionsCompared with PS, SEMS-CL-125I significantly shortens the hospitalization time, reduces the hospitalization expenses and prolongs the survival time of patients with advanced EHCC, which is worthy of clinical promotion and application.
Analysis of the sequencing results of whole genome chromosome copy number variation in isolated fetal pyelectasia
SHI Li, WU Dong-cai, FU Xiao-yan
2020, 45(10): 1322-1324, 1329.   doi: 10.13898/j.cnki.issn.1000-2200.2020.10.003
[Abstract](25) [FullText HTML](11) [PDF 1301KB](0)
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ObjectiveTo investigate the results of copy number variation sequencing(CNV-seq) and prognosis of isolated fetal pyelectasis.MethodsThe interventional prenatal diagnosis was performed in 76 fetuses with isolated pyelectasia, and the data of chromosomal karyotypes and CNV-seq were retrospectively analyzed.The pregnancy outcomes were followed up.ResultsThe analysis results of chromosomal karyotype in 76 fetuses with isolated pyelectasia showed that only 1 case was with D Down's syndrome, and 1 case was with chromosome 9 inversion.The results of CNV-seq analysis in 76 fetuses showed that only 1 case was with Down's syndrome, 2 cases were with polymorphic copy number variation(CNV), and no other CNV with pathogenicity, potential pathogenicity or unknown pathogenicity was found.Among 6 cases with pyelectasia, 51 cases were boys and 25 cases were girls.Two cases were induced labour, which included 1 case with Down's syndrome and 1 case with severe fetal hydronephrosis.In the remaining 74 live births, B-ultrasonography showed no exacerbation of pyelectasia or hydronephrosis.ConclusionsThe vast majority of isolated fetal pyelectasia have a good prognosis, unless the pregnant woman is at high risk for Down's screening or noninvasive prenatal testing, and the routine prenatal CNV-seq analysis is not required.
Relationship between the immuno-deposition of C3 and clinicopathological features of IgA nephropathy
PAN Yan, CHEN Wei-dong
2020, 45(10): 1325-1329.   doi: 10.13898/j.cnki.issn.1000-2200.2020.10.004
[Abstract](28) [FullText HTML](14) [PDF 1043KB](2)
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ObjectiveTo analyze the significance of complement C3 deposition in the mesangial region of glomeruli in IgA nephropathy pathogenesis and progression, so as to provide the basis for disease diagnosis, condition monitoring and prognosis judgment.MethodsThe clinical and pathological examination indexes in patients with IgA nephropathy were retrospectively analyzed.According to the intensity of C3 deposition in the mesangial area, the patients were divided into the negative group[(-)], weak positive group[(±to +)] and strong positive group[(2+ to 3+)], and the corresponding indicators were statistically analyzed.ResultsAccording to the classification of complement C3 deposition intensity, 10 cases(23.3%) in the negative group, 13 cases(30.2%) in weak positive group and 20 cases(46.5%) in strong positive group were identified.With the aggravation of tissue C3 deposition, the blood creatinine and urea nitrogen increased, the eGFR decreased, and the difference of which was statistically significant(P < 0.05 to P < 0.01).However, the differences of the uric acid, 24 h urine protein quantification and microscopic haematuria, blood lipid, blood pressure and blood glucose were not statistically significant(P>0.05).The results of Pearson correlation analysis showed that the intensity of complement C3 was opposite to the value of serum C3, but there was no statistical significance between them(P>0.05).The intensity of C3 immunofluorescence deposition in renal tissue was correlated with the pathological damage, but the difference of pathological grading(Lee grading) was not statistically significant(P>0.05), and the differences of intensity of C3 immunofluorescence deposition in renal tissue among the different mesangial cell proliferation, capillary endothelial cell proliferation, globular sclerosis, and renal tubular interstitial lesions(including interstitial inflammatory cell infiltration, interstitial fibrosis and renal tubular atrophy) were statistically significant(P < 0.05).ConclusionsThe intensity of C3 deposition in the mesangial region of glomeruli in patients with IgA nephropathy is related to the serum creatinine, urea nitrogen, eGFR and pathological damage, and which may be used as an indicator to monitor and predict the prognosis of IgA nephropathy.
Study on the application of ultrasound measurment of optic nerve sheath diameter in the severe preeclampsia with intracranial pressure increasing
DUAN Li-bin, LIANG Xiao-han, WANG Hua-xue, HE Xian-di
2020, 45(10): 1330-1334.   doi: 10.13898/j.cnki.issn.1000-2200.2020.10.005
[Abstract](33) [FullText HTML](16) [PDF 1601KB](1)
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ObjectiveTo investigate the value ment of ultrasound measurment of optic nerve sheath diameter(ONSD) in the severe preeclampsia with intracranial pressure(ICP) increasing.MethodsForty-four pregnant women with severe preeclampsia and 30 single pregnant women without complications were divided into the observation group and control group, respectively.The MRI and ONSD in observation group were detected, and the observation group was subdivided into the normal ICP group and ICP increasing group according to the MRI results.The ONSD was measured in the control group.The differences of ONSD were compared among three groups.The ROC curve was used to explore the optimal threshold for ONSD detection in severe preepilepsy patients complicated with intracranial pressure increasing.ResultsThe differences of the systolic blood pressure, diastolic blood pressure, gestational weeks and ONSD values among three groups were statistically significant(P < 0.01), and the systolic blood pressure and diastolic blood pressure in ICP increasing group were significantly higher than those in control group and ICP normal group(P < 0.01).The gestational weeks in control group were significantly higher than that in observation group(P < 0.01).The ONSD values in ICP increasing group and normal group were significantly higher than that in control group(P < 0.01), and which in ICP increasing group was significantly higher than that in ICP normal group(P < 0.01).Under the ONSD measurement method, the AUC was 0.759 (95% CI:0.606~0.913, P < 0.01), the maximum Youden index was 0.497, the ONSD critical value was 4.0 mm, and the sensitivity was 62.2%.ConclusionsThe ultrasound measurement of ONSD can be used in the diagnosis of severe preepilepsia with ICP increasing, which has certain diagnostic value when ONSD is 4.0 mm.
Clinical observation of unarmed shock therapy combined with acupuncture exercise in the treatment of periarthritis humeroscapularis
CHEN Yan, HU Jin-lu, XIE Hui
2020, 45(10): 1334-1337.   doi: 10.13898/j.cnki.issn.1000-2200.2020.10.006
[Abstract](28) [FullText HTML](12) [PDF 1018KB](0)
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ObjectiveTo explore the rehabilitation effects and feasibility of unarmed shock therapy combined with acupuncture exercise in the treatment of periarthritis humeroscapularis.MethodsAccording to the different treatment methods, 60 patients with periarthritis humeroscapularis were randomly divided into the observation group and control group.The observation group was treated with unarmed shock therapy combined with acupuncture exercise, and the control group was treated with acupuncture exercise.The two effect indexes in two groups were analyzed using the simple McGill pain questionnaire(SF-MPQ) scale and shoulder joint activity Function(Melle) scale.ResultsThe curative effect in observation group was better than that in control group(P < 0.01).The total score of SF-MPQ indexes and Melle score in two groups before treatment were higher than those after treatment(P < 0.01).Before treatment, there was no statistical significance in the total score of SF-MPQ indexes and Melle score between two groups(P>0.05).After treatment, there was no statistical significance in the PRI emotional item of SF-MPQ between two groups(P>0.05), and other indicators and total score of SF-MPQ, and Melle score in control group were higher than those in observation group(P < 0.05).ConclusionsUnarmed shock therapy combined with acupuncture exercise can significantly improve the clinical efficacy of periarthritis humeroscapularis, which is worth popularizing.
Systematic evaluation and Meta-analysis of Fufang Luobuma Pills combined with amiodarone in the treatment of coronary heart disease with ventricular arrhythmias
JIANG Cheng-lin, HU Ye-mei, GAO Huai-lan, BU Jun
2020, 45(10): 1338-1344.   doi: 10.13898/j.cnki.issn.1000-2200.2020.10.007
[Abstract](46) [FullText HTML](29) [PDF 4945KB](11)
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ObjectiveTo evaluate the efficacy and safety of Fufang Luobuma Pills combined with amiodarone in the treatment of coronary heart disease with ventricular arrhythmia.MethodsThe literatures on Fufang Luobuma Pills combined with amiodarone in the treatment of coronary heart disease with ventricular arrhythmia were searched from PubMed, China National Knowledge Infrastructure(CNKI), China Biomedical Literature Database(CBM), VIP Database and WanFang Database by computer.The Cochrane Handbook 5.1.0 was used to evaluate the quality criteria of randomized controlled trials, and the quality and risk of bias of literatures were evaluated, and statistically analyzed using RevMan5.3 software.ResultsA total of 1 033 patients in 9 studies were enrolled, which included 464 cases of treatment group and 569 cases of control group(464 cases of amiodarone group and 105 cases of propafenone group).The results of Meta-analysis showed that the total clinical effective rate of Fufang Luobuma Pills combined with amiodarone was higher than that of amiodarone alone(OR=5.46;95% CI:3.40-8.75;Z=7.04;P < 0.00001;I2=0%) or propafenone alone(OR=2.99;95% CI:1.48-6.07;Z=3.04;P=0.002;I2=0%).The number of ventricular premature beats(SMD=-1.39;95% CI:-1.61--1.17;Z=12.34;P=0.00001;I2=0%) and occurrence of short array ventricular tachycardia(SMD=-1.51;95% CI:-1.73--1.28;Z=13.16;P < 0.00001;I2=0%) in treatment group were significantly reduced compared with those in amiodarone group.The difference of the incidence rate of adverse reaction between two groups was not statistically significant(OR=0.94;95% CI:0.58-1.53;Z=0.25;P=0.80;I2=0%).ConclusionsThe effects of Fufang Luobuma Pills combined with amiodarone in the treatment of coronary heart disease with ventricular arrhythmia is better and safer than that of amiodarone and propafenone alone.
Diagnostic value of PC, SD, PC/SD and FIB-4 in cirrhotic esophageal varices
MA Sha-sha, GAO Chun-ming
2020, 45(10): 1344-1347.   doi: 10.13898/j.cnki.issn.1000-2200.2020.10.008
[Abstract](24) [FullText HTML](9) [PDF 1101KB](0)
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ObjectiveTo investigate the clinical value of spleen longitudinal diameter(SD), platelet count(PC), PC/SD and FIB-4 index in predicting the cirrhotic esophageal varices(EV).MethodsThe clinical data of 134 patients with cirrhosis were collected.The esophageal varices in all patients were examined using gastroscopy.According to the presence or absence of EV, the patients were divided into the EV group and non-EV group, and the EV group was subdivided into the RC (+) group and RC (-) group according to the red color sign(RC) The diagnostic efficacy of PC, SD, PC/SD and FIB-4 in EV were evaluated, and the influencing factors of RC was analyzed.ResultsThe PC, WBC and PC/SD in EV group were lower than those in non-EV group, and the SD, FIB-4, Child-Pugh score and PT in EV group were higher than those in non-EV group(P < 0.05 to P < 0.01).The areas under the curve predicted by PC, SD, PC/SD and FIB-4 for EV were 0.781, 0.811, 0.811 and 0.715, respectively.The area under the curve predicted by SD and PC/SD for EV was 0.822, the sensitivity was 85.4%, and the specificity was 71.1%.The age in RC (+) group was less than that in RC (-) group, and the SD in RC (+) group was greater than that in RC (-) group(P < 0.05 and P < 0.01).The area under the curve of SD for predicting RC in EV group was 0.705, the cutoff value was 151, the sensitivity was 66.1% and the specificity was 64.5%.ConclusionsThe PC, SD, PC/SD and FIB-4 have certain clinical value in predicting EV.The combination of PC/SD and SD can better predict.The SD is an independent risk factor for RC in patients with cirrhotic EV.
Prediction and diagnosis of postmenopausal endometrial cancer by the combination of human epididymal secretory protein 4, carbohydrate antigen 125 and ultrasound
WANG Jian-mei, WANG Yu, ZHOU Hong-ping, ZHANG Ya-lin
2020, 45(10): 1348-1351.   doi: 10.13898/j.cnki.issn.1000-2200.2020.10.009
[Abstract](26) [FullText HTML](11) [PDF 1025KB](0)
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ObjectiveTo investigate the diagnostic value of human epididymal secretory protein 4 (HE4), carbohydrate antigen 125 (CA125) combined with ultrasound in postmenopausal endometrial carcinoma.MethodsA total of 101 patients with postmenopausal endometrial cancer were selected as malignant group, 103 patients with postmenopausal endometrial hyperplasia as benign group, and 105 menopausal healthy examinees as control group.The levels of HE4 and CA125 in three groups were detected.The sensitivity, specificity and diagnostic odds ratio were calculated under combined detection, and the area under the receiver operating characteristic curve (AUC) was calculated.ResultsSeventy-eight abnormal cases were found in malignant group by colorful Doppler ultrasound.The expression level and positive rate of HE4 and CA125 in malignant group were higher than those in benign group and control group, and which in benign group were higher than those in control group(P < 0.05 to P < 0.01).The sensitivity and diagnostic odds ratio of combined diagnosis were higher than that of HE4, CA125 and ultrasound alone(P < 0.01 and P < 0.05), but the specificity between them was not statistically significant(P>0.05).The AUC values of simple HE4, CA125 and ultrasound diagnosis at the best diagnosis point were 0.725, 0.713 and 0.723, respectively, and the AUC value of combined diagnosis of HE4, CA125 and ultrasound was 0.867.ConclusionsCompared with simple diagnosis, the overall diagnostic efficacy of HE4 and CA125 combined with ultrasound for endometrial tumor is better, which has better clinical application and promotion value.
Analysis of the clinical and coronary lesion characteristics in different age patients with acute myocardial infarction
CHEN Tian-ping, ZHANG Nai-ju, XIE Cai-xia, LI Miao-nan, GENG Xu, HU Si-gan, LIU Jin-jun, TANG Bi
2020, 45(10): 1351-1354.   doi: 10.13898/j.cnki.issn.1000-2200.2020.10.010
[Abstract](31) [FullText HTML](13) [PDF 1023KB](1)
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ObjectiveTo investigate the clinical and coronary lesion characteristics in different age patients with acute myocardial infarction(AMI).MethodsTwo hundred and one AMI patients were detected using emergency coronary angiography, and divided into the young and middle-aged group(age < 60 years old, n=70) and elderly group(age ≥ 60 years old, n=131) according to their ages.The clinical data and coronary artery disease data were compared between two groups.ResultsElderly patients with AMI were more prone to have in-hospital death and heart failure compared with young and middle-aged patients(P < 0.05).The levels of red blood cell count, hemoglobin, hematocrit, reticulocyte count, lymphocyte count, eosinophil count, alanine aminotransferase, cholinesterase, total protein, albumin, uric acid, total cholesterol, low density lipoprotein and apolipoprotein B in young and middle-aged group were higher than those in elderly group(P < 0.05 to P < 0.01), and the level of lipoprotein a in young and middle-aged group was lower than that in elderly group(P < 0.05).In the young and middle-aged group, the single-vessel lesion and low Gensini score were the main performance, and the probability of no/slow reflow was low.In the elderly group, the coronary arteries were mainly composed of multiple vessels, calcification lesions and high Gensini score, and no/slow reflow was easy to occur during the operation.The difference of which between two groups was statistically significant(P < 0.05 to P < 0.01).ConclusionsThe levels of blood pressure, blood glucose and blood lipid in young and middle-aged patients are higher, and the coronary artery lesions are mainly single-branch and low Gesini score lesions.In the elderly patients, the coronary artery lesions are mainly diffused long lesions and calcificated lesions, and no/slow reflow is easy to occur during the operation.
Comparsion of the clinical effects between intrapascial and interfascial nerve-sparing in laparoscopic radical prostatectomy for prostate cancer
CHEN Zhi-jun, WANG Sheng, WANG Cheng-yong, LIU Jian-min, LI Qing-wen, GUAN Han
2020, 45(10): 1355-1358, 1362.   doi: 10.13898/j.cnki.issn.1000-2200.2020.10.011
[Abstract](27) [FullText HTML](11) [PDF 1445KB](1)
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ObjectiveTo compare the clinical effects between intrafascial and interfascial nerve-sparing in laparoscopic radical prostatectomy.MethodsThe clinical data of 41 prostate cancer patients treated with laparoscopic radical prostatectomy were retrospectively analyzed.Twenty cases were treated with intrafascial nerve-sparing technique(intrafascial group), and 21 cases were treated with interfascial nerve-sparing technique(interfascial group).The perioperative indicators, erectile function and early urinary control were compared between two groups.ResultsThe number of using urinal pads in intrafascial group was significantly better than that in interfascial group after 3 and 6 months of operation(P < 0.05).In the intrafascial group, the recovery of erectile function was significantly improved after 6 months of operation(66.7% vs 33.3%, P < 0.05).ConclusionsCompared with the interfascial nerve-sparing technique, the intrafascial nerve-sparing technique can provide similar surgical results, and obstain better early urinary control and restoration of erectile function.
Study on the relationship between serum neurotransmitter concentration and severity of disease in patients with breast cancer complicated with depression
CHEN Lin, LI Jiang-bo, RONG Wei
2020, 45(10): 1359-1362.   doi: 10.13898/j.cnki.issn.1000-2200.2020.10.012
[Abstract](27) [FullText HTML](12) [PDF 1029KB](0)
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ObjectiveTo investigate the relationship between serum neurotransmitter concentration and severity of disease in patients with breast cancer complicated with depression.MethodsSixty breast cancer complicated with depression patients(SDS score ≥ 53 points) and 60 breast cancer complicated without depression patients(SDS score < 53 points) treated with adjuvant chemotherapy after radical mastectomy were divided into the observation group and control group, respectively.According to SDS score, the observation group was subdivided into the severe depression group(18 cases, SDS score ≥ 72 points), moderate depression group(20 cases, SDS score of 63 to 72 points) and mild depression group(22 cases, SDS score of 53 to 62 points).The levels of 5-hydroxytryptophan(5-HT), neuropeptide Y(NPY), dopamine(DA) and norepinephrine(NE) in peripheral blood in two groups were measured, and their relationship with the severity of depression in the observation group was observed.ResultsThe serum levels of 5-HT, DA, NPY and NE in observation group were significantly lower than those in control group(P < 0.01).The serum levels of 5-HT, DA, NPY and NE in severe depression group were lower than those in moderate depression group and mild depression group(P < 0.01), and the serum levels of 5-HT, DA, NPY and NE in moderate depression group were lower than those in mild depression group(P < 0.01).The serum levels of 5-HT, DA, NPY and NE in the observation group after anti-depression treatment significantly increased compared with before treatment(P < 0.01).The serum levels of 5-HT, DA, NPY and NE in breast cancer complicated with depression patients treated with chemotherapy after operation were negatively correlated with the SDS score(r=-0.575, -0.601, -0.568, -0.612, P < 0.01).ConclusionsThe serum neurotransmitter concentration decreases in breast cancer complicated with depression patients, and the neurotransmitter concentration is negatily correlated with the severity of depression.
Application value of three-dimensional reconstruction in minimally invasive pulmonary surgery
LI Xiao-jun, ZHANG Lei, TANG Zhen, ZHU Xiao, GONG Hui-yuan, WANG Biao, XING Fu-bao, GAO Xiong
2020, 45(10): 1363-1366.   doi: 10.13898/j.cnki.issn.1000-2200.2020.10.013
[Abstract](27) [FullText HTML](9) [PDF 1883KB](0)
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ObjectiveTo explore the clinical value of the preoperative planning and intraoperative real-time navigation using the three-dimensional-reconstruction of bronchi, pulmonary vessels and tumors in thoracoscopic pneumonectomy.MethodsThe clinical data of 25 non-small cell lung cancer patients treated with thoracoscopic radical lobectomy and 25 cases treated with segmental resection of pulmonary nodules were retrospectively analyzed.All patients were detected using chest thin-slice CT scan before operation, and the bronchus, pulmonary artery and pulmonary vein were reconstructed with DeepInsight software, and the pulmonary nodules, tumors or enlarged lymph nodes were also reconstructed.The accurate preoperative planning was carried out through the preoperative three-dimensional-reconstruction, especially the variation of pulmonary bronchus and blood vessels.The accurate operation were implemented using the real-time navigation of three-dimensional-reconstruction of tumors, enlarged lymph nodes and pulmonary vessels.The intraoperative conversion to thoracotomy, operation time, intraoperative bleeding and postoperative hospital stay, drainage tube removal time, total drainage volume and perioperative complications were recorded.ResultsThe anatomical structure, variation of bronchus and pulmonary vessels were clearly reconstructed in all patients, and the relationship between the central tumor, enlarged lymph nodes and vessels were satisfactory.The locatory of pulmonary nodules in the pulmonary segments was clearly identified, and the preoperative planning was accurately carried out.The intraoperative real-time navigation was carried out in all patients, and the precise surgery was carried out according to the preoperative plan.The operation was successfully completed, and no conversion to thoracotomy or intraoperative accidental bleeding were found.The operative time was(147.60±37.77)min, the intraoperative blood loss was(33.82±22.17)mL, the postoperative hospital stay was(7.02±1.78)d, the drainage tube removal time was(4.68±1.60)d, and the postoperative total drainage volume was (221.00±135.03)mL.There were not serious complications and death in perioperative period.ConclusionsThe application of chest thin-slice CT data in preoperative three-dimensional-reconstruction and intraoperative navigation can accurately, effectively and safely guide the thoracoscopic lobectomy and pulmonary segmentectomy.
Analysis of the factors influencing the severity of hyperlipidemic pancreatitis
REN Pan-pan, YAO Xi-qing, ZHOU Wei, LUO Ji-ye
2020, 45(10): 1367-1369, 1374.   doi: 10.13898/j.cnki.issn.1000-2200.2020.10.014
[Abstract](22) [FullText HTML](10) [PDF 1012KB](0)
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ObjectiveTo analyze the influencing factors of the severity of hyperlipidemic pancreatitis(HLP).MethodsEighty patients with HLP were divided into the hyperlipidemia severe acute pancreatitis group(HLSAP group, 31 cases) and stable group(HLP group, 49 cases).The general data, blood lipid level and other laboratory examination indexes were collected, the progress of patients' condition during hospitalization was analyzed, and the independent influencing factors of HLP patients' condition were analyzed using multiple logistic regression analysis.ResultsThe results of multiple logistic regression analysis showed that the age, heart rate, breathing rate, 24 h urine volume, APACHE Ⅱ score, triglyceride, albumin, serum creatinine, blood glucose and arterial oxygen partial pressure were the independent factors influencing the severity of HLP patients(P < 0.05).ConclusionsThe age, heart rate, respiratory rate, 24 h urine volume, APACHE Ⅱ score, triglyceride, albumin, creatinine, blood glucose and arterial oxygen partial pressure are closely related to the development of HLP.Early intervention should be emphasized in clinic.
Clinical application value of grip strength measurement in the assessment of nutritional status of patients with cirrhosis
KANG Ying, QI Ping-ping, CAO Lin-lin, YANG Xin
2020, 45(10): 1370-1374.   doi: 10.13898/j.cnki.issn.1000-2200.2020.10.015
[Abstract](27) [FullText HTML](9) [PDF 1033KB](0)
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ObjectiveTo explore the application value of grip strength(GS) measurement in the assessment of nutritional status of patients with cirrhosis.MethodsThe nutritional status of 76 patients with cirrhosis were assessed using MNA-SF.According to the MNA-SF score, the patients were divided into the normal nutrition group(n=21), malnutrition risk group(n=30) and malnutrition group(n=25).The anthropometric index, human component index, biochemical index and resting energy consumption in three groups were measured, and their correlation with GS were analyzed.ResultsThe GS, MAC, AMC, CC, TSF and BMI in normal nutrition group were significantly higher than those in malnutrition risk group and malnutrition group(P < 0.01);and the GS, MAC, AMC, CC, TSF and BMI in malnutrition risk group were significantly higher than those in malnutrition group(P < 0.01).There was no statistical significance in the ICW, ECW and TBW among three groups(P>0.05).The ECW/TBW in normal nutrition group was significantly lower than that in malnutrition risk group and malnutrition group(P < 0.05), and the ECW/TBW in malnutrition risk group was significantly lower than that in malnutrition group(P < 0.01).In malnutrition risk group and malnutrition group, the REE Prre were significantly higher than REE Meal(P < 0.01), the REE Prre in malnutrition risk group and malnutrition group were significantly higher than that in normal group(P < 0.01), and the REE Prre in malnutrition group was significantly higher than that in malnutrition risk group(P < 0.01).The results of Pearson correlation analysis showed that GS was positively correlated with MAC, AMC, CC, BMI and ALB(P < 0.01), negatively correlated with TSF and REE Prre(P < 0.01), and not correlated with TRF, PA, Hb, FN, RBP and TLC(P>0.05).ConclusionsGS is closely related to other nutritional indicators in patients with cirrhosis.Therefore, GS measurement can be used as a nutritional status assessment method in patients with cirrhosis, and it can be further popularized in clinical practice.
Application of ropivacaine combined with dexmedetomidine guided by ultrasound in quadratus lumborum block in elderly hip replacement
GAO Guo-hao, LIU Meng-ya, ZHU De-hao, LÜ Ai-jun, WANG Nan-hai
2020, 45(10): 1375-1379, 1383.   doi: 10.13898/j.cnki.issn.1000-2200.2020.10.016
[Abstract](32) [FullText HTML](14) [PDF 1066KB](1)
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ObjectiveTo evaluate the perioperative analgesic effects of ropivacaine combined with dexmedetomidine guided by ultrasound in quadratus lumborum block in elderly hip replacement.MethodsA total of 90 patients treated with unilateral total hip replacement under general anesthesia of laryngeal mask was randomly divided into the control group(group C, laryngeal mask general anesthesia group), group R(ropivacaine block group) and group RD(compound drug block group)(30 cases in each group).The quadratus lumborum block in group R and group RD were performed in the anesthetic intensive care unit before 30 min of admission, and the group R and group RD were injected with 20mL of 0.25% ropivacaine, and 20 mL of 0.25% ropivacaine containing 1 μg/kg dexmedetomidine, respectively.The heart rate(HR) and mean arterial pressure(MAP) in three groups were recorded before induction, laryngeal mask airway(LMA) insertion, dermectomy, reaming and removal of LMA.The amount of intraoperative remifentanil and propofol, extubation time, postoperative analgesia of sufentanil and parecoxib were recorded in three groups.The postoperative adverse reactions in all cases were recorded.The rest VAS scores after 4, 8, 12, 24, 36 and 48h of operation, movement VAS scores after 24, 36 and 48h of operation, and maximum flexion and abduction range of hip joint after 24, 36 and 48h of operation were evaluated in three groups.ResultsAt T0, there was no statistical significance in MAP and HR among three groups(P>0.05).At T1 and T4, there was no statistical significance in MAP among three groups(P>0.05).At T2 and T3, the MAP in group R and group RD was lower than that in group C(P < 0.01), and there was no statistical significance in the MAP between group R and group RD(P>0.05).At T1-T4, the HR in group R and group RD was lower than that in group C(P < 0.01), and there was no statistical significance in the MAP and HR between group R and group RD(P>0.05).The intraoperative usage amount of remifentanil and propofol, postoperative usage amount of sufentanil, number of cases of remedial analgesia, VAS scores of rest and movement in group C, group R and group RD gradually decreased at each time point, and the differences of those among three groups were statistically significant (P < 0.05 to P < 0.01).The maximum flexion and abduction range of hip joint in group C, group R and group RD gradually increased at each time point, and the differences of those among three groups were statistically significant(P < 0.05 to P < 0.01).The incidence rates of nausea and vomiting, and remedial analgesia in group R and group RD were lower than those in group C(P < 0.05 to P < 0.01), and the difference of which between group RD and group R was not statistically significant(P>0.05).ConclusionsThe perioperative analgesic effect of ropivacaine combined with dexmedetomidine guided by ultrasound in quadratus lumborum block in elderly hip replacement is ideal, which is conducive to postoperative rehabilitation.
A clinical study on the effects of masseter injection with type A botulinum toxin on the proportion of female lower face in North Anhui
LI Ye-ye, SHAN Tian-tian, LING Zi-xin, ZU Wen-xuan, JIANG Bang-hong, CHEN Shi-wen, YAO Yang
2020, 45(10): 1380-1383.   doi: 10.13898/j.cnki.issn.1000-2200.2020.10.017
[Abstract](21) [FullText HTML](7) [PDF 1696KB](0)
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ObjectiveTo compare the difference of the proportion of lower face between North Anhui female and Asian beautiful stars using Photoshop image processing software, and investigate the effects of masseter injection with type A botulinum toxin on the difference.MethodsThe front and lateral photographs of 40 North Anhui females before and after masseter injection with type A botulinum toxin and 40 Asian beautiful stars were measured using the Photoshop image processing software.The proportions of lower face between North Anhui female before injection and Asian beautiful stars were compared.The proportions of lower face in North Anhui females after masseter injection with type A botulinum toxin and Asianeautiful stars were statistically analyzed to investigate the effects of masseter injection with type A botulinum toxin on the lower face of North Anhui female.ResultsAmong the 11 facial proportion indicators, the ratios of lower/upper width, lower/middle width, lower/eyelid width, lower/mouth width, lower/upper height, lower/morphological height and lower/nose height in North Anhui females were greater than those in Asian stars(P < 0.05 to P < 0.01).The differences of 7 indexes of masseter injection with type A botulinum toxin were not statistically significant compared with female stars (P>0.05).ConclusionsThere is a certain difference in the proportion of lower face between women in North Anhui and Asian beautiful stars.The masseter injection with type A botulinum toxin can change the width of lower face.The aesthetic proportion of the lower face can be used as a reference for clinical medical cosmetology to guide clinical plastic surgery.
Expression of STC2 protein in endometrial cancer and its relationship with prognosis
ZHOU Wei, DAI Xiao-yun, WANG Zhong-hai
2020, 45(10): 1384-1386, 1391.   doi: 10.13898/j.cnki.issn.1000-2200.2020.10.018
[Abstract](21) [FullText HTML](8) [PDF 1108KB](1)
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ObjectiveTo investigate the expression levels of stanniocalcin-2(STC2) protein in endometrial cancer and its relationship with prognosis.MethodsA total of 78 samples of endometrial cancer were collected.The expression level of STC2 protein in all cases were measured using immunohistochemistry, and the correlation of which with clinical characteristics was analyzed.The relationship between STC2 expression level and relapse-free survival rate was compared.ResultsThe results of immunohistochemistry showed that the tumor cells with positive STC2 staining in 61 samples were found, which accounted for 65.38%.Based on staining score system, the non-or low-expression of STC2 in 35 samples(44.87%) and high-expression of STC2 in 43 samples (55.13%) were identified.There was no statistical significance in the age between two groups(P>0.05), but the FIGO staging, lymphatic vascular invasion, myometrium invasion and cervical involvement in high-expression group significantly aggravated compared with the non-expression and low-expression group, and the difference of which was statistically significant(P < 0.05 to P < 0.01).All patients were followed up for 12 months.During the following-up, the tumor recurrence in 14 cases(17.95%) found, which included 2 cases(5.71%) in non-or low-expression group and 12 cases(27.91%) in high-expression group.The relapse-free survival rate in high-expression group was lower than that in non-or low-expression group(P < 0.05).ConclusionsThere is light-moderate STC2 expression in most cases of endometrial cancer, and its high expression level is associated with the poor prognosis.STC2 may be a prediction marker for the prognosis of endometrial cancer.
Effect of bifidobacterium triple viable preparation on the postoperative recovery of patients with upper gastrointestinal perforation
YU Zhao-xiang, ZAN Jian-bao, MIAO Xiang, HE Cheng-long
2020, 45(10): 1387-1391.   doi: 10.13898/j.cnki.issn.1000-2200.2020.10.019
[Abstract](23) [FullText HTML](14) [PDF 1041KB](0)
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ObjectiveTo investigate the safety and effectiveness of bifidobacterium triple viable preparation in the postoperative recovery of patients with upper gastrointestinal perforation.MethodsSixty patients with upper gastrointestinal perforation were divided into the observation group and control group by random number table method(30 cases in each group).The control group was treated with early enteral nutrition based on the basic treatment regimen, and the observation group was treated with bifidobacterium triple viable preparation preparation based on the control group.The total white blood cell count(WBC), neutrophil ratio, C-reactive protein(CRP), procalcitonin(PCT), interleukin-6(IL-6), CD3+T cells, CD4+ T cells, CD8+T cells, CD4+/CD8+ and other indicators were detected in two groups, and the hospital stay and incidence rate of complications were recorded.ResultsThe differences of the levels of WBC, neutrophil ratio, CRP, PCT, IL-6 and T lymphocyte subsets between two groups before and after 1 and 4 days of surgery were not statistically significant(P>0.05).After 4 days of surgery, the neutrophil ratio and IL-6 level in observation group were lower than those in control group(P < 0.05).After 7 days of surgery, the WBC and neutrophil ratio in two groups basically returned to normal, and the difference of which was not statistically significant(P>0.05), and the levels of CRP, PCT and IL-6 in observation group were lower than those in control group(P < 0.05 to P < 0.01).After 4 and 7 days of operation, the proportions of CD3+ T cells and CD4+ T cells, and CD4+/CD8+ in observation group were higher than those in control group(P < 0.05 to P < 0.01), the proportion of CD8+ T cells in observation group was significantly lower than that in control group(P < 0.01).The length of hospital stay and incidence rate of complications in observation group were lower than those in control group(P < 0.01 and P < 0.05).ConclusionsThe bifidobacterium triple viable preparation in the treatment of upper gastrointestinal perforation can strengthen the immunity of patients, reduce systemic inflammatory reaction, enhance intestinal barrier, promote rapid recovery of intestinal function and reduce the incidence of postoperative complications, which is worthy of promotion in clinic.
Comparison of the clinical outcome of laparoscopic radical prostatectomy between transperitoneal and extraperitoneal approaches
WU Hong-liang, GUAN Han, CHEN Zhi-jun, YANG Shuai, DAI Chang-yuan, WANG Cheng-yong, WANG Sheng, LIU Jian-min, LI Qing-wen
2020, 45(10): 1392-1394, 1398.   doi: 10.13898/j.cnki.issn.1000-2200.2020.10.020
[Abstract](26) [FullText HTML](6) [PDF 1031KB](0)
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ObjectiveTo compare the clinical outcome of laparoscopic radical prostatectomy(LRP) between transperitoneal and extraperitoneal approaches.MethodsThe clinical data of 50 patients treated with LRP from January 2017 to January 2020 were retrospectively analyzed.The patients were divided into the transperitoneal group(29 cases) and extraperitoneal group(21 cases) according to the surgical approach.ResultsThere was no statistical significance in the intraoperative and postoperative blood transfusion rate between two groups(P>0.05).The operative time, intraoperative blood loss, time of complete oral diet, removal time of drainage tube and hospital stay time in the extraperitoneal group reduced compared with the transabdominal group(P < 0.05 to P < 0.01).The rate of immediate urinary continence after catheter removal in transabdominal group was lower than that in extraperitoneal group(P < 0.05).The incidence rate of perioperative complication in transabdominal group was higher than that in extraperitoneal group(P < 0.05).ConclusionThe extraperitoneal-LRP and transabdominal-LRP are safe and effective, there is no significant difference in the positive rate of cutting edge.The extraperitoneal approach has the advantages of shorter operation time, shorter hospital stay, less bleeding and fewer complications.
The clinical predictive value of electrocardiogram in patients with variant angina for malignant ventricular arrhythmia
ZHANG Xian-hong, YANG Li-na
2020, 45(10): 1395-1398.   doi: 10.13898/j.cnki.issn.1000-2200.2020.10.021
[Abstract](20) [FullText HTML](8) [PDF 1122KB](0)
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ObjectiveTo explore the clinical predictive value of electrocardiogram in patients with variant angina(VA) for malignant ventricular arrhythmia(MVA).MethodsOne hundred and thirty-six patients with VA were divided into the NMVA group and MVA group according to whether to merge MVA(68 cases each group).The electrocardiogram in two groups were detected.The ECG parameters between two groups were compared and the likelihood of MVA was predicted.ResultsDuring acute exacerbation, the QT interval(cQT), QT interval dispersion(cQTd) of the electrocardiogram parameters, corrected T-peak to the end of the T-wave(cTp-e), corrected Tp-e dispersion(cTp-ed), interval between the T wave peak and T wave end(Tp-e/QT) and ST segment elevation(STE) value in MVA group were significantly higher than those in NMVA group(P < 0.05 to P < 0.01).The results of ROC curve analysis showed that the area under the ROC curve (AUC) of cTp-e, cTp-ed, Tp-e/QT and STE were significantly larger than those of cQTd(P < 0.05), which of Tp-e/QT was significantly greater than that of cTp-ed and STE(P < 0.05), and there was no statistical significance that of between cTp-ed and STE(P>0.05).The predictive value of cQTd and STE were moderate, and the predictive value of the cTp-e, cTp-ed and Tp-e/QT were high.The cTp-ed and Tp-e/QT were closely related to the MVA in VA patients(P < 0.05).ConclusionThe cQTd, cTp-e, cTp-ed, Tp-e/QT and STE can predict the occurrence of MVA.The predictive value of cTp-ed and Tp-e/QT are higher, and which can be used as the primary observation indicators to predict the occurrence of MVA in patients with VA.
Prophylactic effects of novel anticoagulants on stroke and cognitive impairment in elderly patients with paroxysmal atrial fibrillation
XUE Zhi-hui, LI Rui
2020, 45(10): 1399-1402.   doi: 10.13898/j.cnki.issn.1000-2200.2020.10.022
[Abstract](21) [FullText HTML](7) [PDF 1029KB](0)
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ObjectiveTo investigate the prophylactic effects of novel anticoagulants on stroke and cognitive impairment in elderly patients with paroxysmal atrial fibrillation.MethodsA total of 646 elderly patients with paroxysmal atrial fibrillation were divided into the coagulation factor Xa inhibitor group(n=318, group A), coagulation factor Ⅱ ainhibitor group(n=145, group B) and warfarin group(n=183, group C) according to the used anticoagulant.In three groups, the incidence of stroke, cognitive impairment and other events were prospectively analyzed, and the cognitive function was evaluated using the mini-mental status examination(MMSE).ResultsThe differences of the incidence rates of stroke, bleeding and mortality among three groups were not statistically significant during 24 months of following-up(P>0.05).The differences of the incidence rates of mild cognitive impairment and MMSE scores among three groups were not statistically significant at baseline and after 6 months and 12 months of anticoagulant therapy(P>0.05).The retest results after 24 months of anticoagulant therapy showed that the incidence rates of mild and above cognitive impairment, and MMSE scores in A, B and C group were (14.7%, 15.7% and 24.4%) and[(27.45±3.28), (27.26±3.14) and (26.13±3.54)], respectively.The differences in the incidence rates of cognitive impairment and MMSE score among three groups were statistically significant(P < 0.05).ConclusionThe novel anticoagulant have good efficacy and safety in atrial fibrillation-related stroke, and may play a positive role in the prevention of cognitive impairment in patients with atrial fibrillation.
Risk factors of frailty in elderly patients with hypertension, and their relationship with poor prognosis
CHEN Li-li, WEN Li-wei
2020, 45(10): 1403-1406.   doi: 10.13898/j.cnki.issn.1000-2200.2020.10.023
[Abstract](23) [FullText HTML](10) [PDF 1011KB](3)
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ObjectiveTo explore the risk factors of frailty in elderly patients with hypertension, and their relationship with poor prognosis.Methods The frailty assessment in 420 patients with hypertension were implemented using the Fried scale, and all patients were divided into the frailty group and non-frailty group according to the evaluation results.The related influencing factors of frailty in elderly hypertensive patients were analyzed, and the risk factors of frailty were analyzed using multivariate logistic analysis.The readmission of the patients was followed up, and the relationship between frailty and readmission in elderly patients with hypertension was analyzed by cox regression model.ResultsAmong 420 elderly patients with hypertension, 165 cases were in the frailty group(accounting for 39.29%), and 255 patients in the non-frailty group(accounting for 60.71%).The non-frailty group included 95 normal patients(22.62%) and 160 pre-frailty patients(38.09%).The results of univariate analysis showed that the differences of the age, MNA-SF score, MMSE score, number of complications, osteoporosis, coronary heart disease, cerebrovascular disease, chronic obstructive pulmonary disease and cardiac insufficiency were statistically significant between the two groups(P < 0.05 to P < 0.01), and the differences of the gender, body mass index, blood pressure, smoking history, drinking history and diabetes were not statistically significant between the two groups(P>0.05).The results of the dichotomous logistic regression analysis showed that the age, malnutrition, cognitive decline, osteoporosis, and cardiac insufficiency were the independent risk factors of frailty in elderly hypertensive patients(P < 0.01).The rate of readmission in frailty group was significantly higher than that in non-frailty group(51.52% vs 25.49%)(P < 0.01).The results of multivariate cox model analysis showed that the age, weakness, anemia, ancomorbidities and positive urinary protein were associated with readmission of patients(P < 0.01).ConclusionThe risk of readmission in elderly patients with hypertension complicated with frailty is higher than that in non-frailty patients.Managing the risk factors of frailty and adjusting the treatment plan can improve the quality of life and prognosis of patients.
Distribution of different subtypes of HPV in patients with high-grade cervical lesions
XIANG Yuan-yuan, WANG Qing, ZHANG Bei
2020, 45(10): 1407-1409, 1413.   doi: 10.13898/j.cnki.issn.1000-2200.2020.10.024
[Abstract](24) [FullText HTML](7) [PDF 1013KB](0)
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ObjectiveTo investigate the distribution of different subtypes of human papillomavirus(HPV) in patients with high-grade cervical lesions.MethodsA total of 110 patients with high-grade cervical lesions were examined using thiprep cytology test, HPV typing and colposcopy biopsy.The distribution of different HPV genotypes in patients were observed.ResultsAmong 110 patients, the positive HPV in 91 cases were found, and the positive rate of which was 82.7%.Among the 91 HPV-positive patients, the top 5 genotype of HPV were HPV16(28.2%), HPV58(13.0%), HPV52(11.4%), HPV18(11.4%) and HPV33(10.7%), respectively.There were 62 cases of single HPV infection and 29 cases of multiple HPV infection.HPV16 and HPV18 were more common in single infection, and HPV58, HPV33, HPV16 and HPV52 were more common in multiple infection.In CIN Ⅱ and CIN Ⅲ level patients, the single infection of HPV16 was the highest.The single infection rate of CIN Ⅲ level was higher than that of CIN Ⅱ level(P < 0.05).ConclusionWith the aggravation of high-grade cervical lesions, the infection rate of HPV16 increases, the infection rates of HPV16, HPV58, HPV18, HPV33 and HPV52 in high-grade cervical lesions are high, and the detection of which is helpful for the recognition of high-grade cervical lesions.
Effect of stellate ganglion block guided by ultrasound on the pain, immunity and antioxidant capacity after head and face surgery
FANG Yi, LIU Song-hua, LI Qiong-can
2020, 45(10): 1410-1413.   doi: 10.13898/j.cnki.issn.1000-2200.2020.10.025
[Abstract](22) [FullText HTML](10) [PDF 1024KB](0)
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ObjectiveTo investigate the effects of stellate ganglion block guided by ultrasound on pain, immunity and antioxidant capacity after head and face surgery.MethodsEighty patients treated with craniofacial surgery were randomly divided into the observation group and control group(40 cases each group).The observation group was treated with right stellate ganglion block guided by ultrasound before anesthesia induction, while the control group was treated routine general anesthesia.The changes of pain digital scores at different times after operation were compared between two groups.The time of self-eating, getting out of bed and hospitalization in two groups after operation were analyzed, and the immune function, antioxidant ability and complications 48 h after operation were compared between two groups.ResultsThe differences of the pain digital score between two groups at different times were statistically significant after operation(P < 0.01).The pain digital scores in two groups at different time-points decreased, and which in observation group was lower than that in control group(P < 0.01).The pain scores in two groups showed a decreasing trend with time going on(P < 0.01).The time of postoperative self-eating and getting out of bed in observation group were earlier than those in control group, and the time of hospitalization after operation was shorter than that in control group(P < 0.01).The levels of IgA, IgG and SOD in observation group were higher than those in control group after 48 h of operation, and the level of MDA of antioxidant capacity index in observation group was lower than that in control group(P < 0.01).The total incidence rate of tachycardia, anesthesia recovery delay, postoperative hemorrhage and postoperative infection in observation group was lower than that in control group(P < 0.01).ConclusionFor patients treated with head and face surgery, the right stellate ganglion block guided by ultrasound can effectively relieve the postoperative pain, improve the body immunity and antioxidant capacity, and reduce complications.
Analysis of the risk factors of vascular crisis after free flap transplantation in oral and maxillofacial region
LIU Chang, ZHANG Kai, XU Jin-cheng, WU Zhi-gang, YANG Dong-kun, HU Kai
2020, 45(10): 1414-1416.   doi: 10.13898/j.cnki.issn.1000-2200.2020.10.026
[Abstract](28) [FullText HTML](11) [PDF 1001KB](1)
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ObjectiveTo explore the risk factors of vascular crisis after free flap transplantation in oral and maxillofacial region.MethodsThe clinical data of 226 oral and maxillofacial defects patients repaired by free flap transplantation of forearm flap were retrospectively analyzed.The gender, age, absence or presence of vascular crisis, type of vascular crisis, history of diabetes mellitus, blood glucose level at admission, history of hypertension and average blood pressure at admission were collected, and the risk factors of postoperative vascular crisis were analyzed.ResultsAmong 226 patients, the vascular crisis in 51 cases were identified, which included 41 cases with venous crisis and 10 cases with arterial crisis.The results of univariate analysis showed that the history of diabetes mellitus and high blood glucose were the influencing factors of the occurrence of vascular crisis(P < 0.01 and P < 0.05).The results of the multivariate logistic regression analysis showed that the history of diabetes mellitus was the risk factor of the occurrence of vascular crisis(OR=4.646, P < 0.01).ConclusionThe risk of vascular crisis in diabetic patients treated with free flap transplantation is high.For such patients, the free flap should be cautiously used for repair.When it is necessary to use, it is necessary to pay attention to the occurrence of vascular crisis to ensure the survival of flap.
2020, 45(10): 1417-1419.   doi: 10.13898/j.cnki.issn.1000-2200.2020.10.027
[Abstract](27) [FullText HTML](9) [PDF 987KB](0)
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2020, 45(10): 1419-1421.   doi: 10.13898/j.cnki.issn.1000-2200.2020.10.028
[Abstract](20) [FullText HTML](8) [PDF 992KB](1)
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A study on the correlation between the symptoms of school-age children with attention deficit hyperactivity disorder and maternal depression and anxiety
JIANG Ting-ting, WANG Yu-qing, ZHU Ping, WANG Jun, ZHU Mei, LIU Guo-dong
2020, 45(10): 1422-1425.   doi: 10.13898/j.cnki.issn.1000-2200.2020.10.029
[Abstract](28) [FullText HTML](9) [PDF 1023KB](1)
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ObjectiveTo analyze the correlation between the symptoms of school-age children with attention deficit hyperactivity disorder(ADHD) and maternal depression and anxiety.MethodsAccording to the diagnostic criteria of diagnostic and statistical manual of mental disorders(DSM-V), 120 school-age children with ADHD and 120 normal school-age children were divided into the case group and control group, respectively.The anxiety and depression in two groups were evaluated and compared by the self-rating depression scale(SDS) and self-rating anxiety scale(SAS).The symptoms and behavior problems of ADHD children were assessed using SNAP-IV.The correlations between children's ADHD symptoms and their mothers' depression and anxiety were analyzed.In combination with the time and duration of the first discovery of symptoms, the correlation between children's ADHD symptoms and maternal depression and anxiety scores were analyzed.ResultsThe standard scores of SDS and SAS of mothers in case group were significantly higher than those in control group(P < 0.01), and the severity of depression and anxiety of mothers in case group were significantly higher than those in control group(P < 0.01).The standard scores of SDS and severity of depression of mothers in preschool age subgroup were higher than those in school-age subgroup(P < 0.01).The SNAP-IV hyperactivity factor score and total score were positively correlated with the standard scores of SAS in preschool age subgroup(P < 0.01 and P < 0.05).There was not significant correlation between the scores of attention deficit factors in ADHD children and standard score of SAS of mothers(P>0.05), and the scores of other factors and total score in ADHD children were positively correlated with the standard scores of SDS and SAS of mothers in school-age subgroup(P < 0.05 to P < 0.01).ConclusionsThe mothers of schoo-age children with ADHD are prone to have depression and anxiety.According to the time of the discovery of symptoms, the symptoms of school-age children with ADHD are correlated with maternal depression and anxiety to varying degrees.
Study on the relationship between emotional intelligence and occupational commitment of nurses
JIANG Guo-ying, YU He-jun, YANG Yu-jie
2020, 45(10): 1426-1428, 1431.   doi: 10.13898/j.cnki.issn.1000-2200.2020.10.030
[Abstract](21) [FullText HTML](9) [PDF 1010KB](0)
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ObjectiveTo understand the status quo of professional commitment of registered nurses of tertiary first-class hospitals in Anhui, analyze the relationship between emotional intelligence and occupational commitment, and provide reference for nursing managers.MethodsThe cluster sampling method was conducted, and 920 registered nurses from three tertiary first-class hospitals in Anhui were investigated using emotional intelligence scale and professional commitment scale.ResultsThe differences of the scores of registered nurses with different hospital types, positions, employment methods, titles, nursing satisfaction, health status, professional interest and annual income were statistically significant(P < 0.05 to P < 0.01).The total score and dimensions of emotional intelligence were positively correlated with the total score and dimensions of occupational commitment(P < 0.01).The results of regression analysis showed that the more interested in nursing specialty, higher the total score of emotional intelligence and more satisfied the nursing work were, the higher the score of professional commitment of nurses in provincial grade tertiary first-class hospitals was.ConclusionsThe nursing managers should pay attention to the cultivation of nurses' emotional intelligence to improve their professional commitment.
Application of transformational learning model in cultivating critical thinking ability of stomatology students
LI Jian-cheng, SONG Pei-jun, YANG Dong-kun, HU Kai, LIAO Sheng-kai, LIU Chang
2020, 45(10): 1429-1431.   doi: 10.13898/j.cnki.issn.1000-2200.2020.10.031
[Abstract](29) [FullText HTML](13) [PDF 994KB](2)
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ObjectiveTo explore the application of transformational learning model in cultivating the critical thinking ability for dental medicine students.MethodsA total of undergraduates majoring in dentistry, grade of 2016, were randomly divided into observation group and control group.The traditional learning method was applied in control group, while the transformational learning method was adopted in observation group.The effects of learning in the two groups with different teaching methods were evaluated.ResultsThe students in the observation group under transformational learning model performed significantly better than those in the control group under traditional teaching in terms of theoretical performance, operational performance and critical thinking ability (P < 0.05 to P < 0.01).ConclusionsTransformational learning plays an important role in oral teaching.It can enhance students' learning ability and improve students' critical thinking ability.It is an efficient and innovative teaching method that is worthy of promotion and application.
Study on online teaching method under the background of COVID-19 in health servic management cours
ZHOU Huan
2020, 45(10): 1432-1435.   doi: 10.13898/j.cnki.issn.1000-2200.2020.10.032
[Abstract](28) [FullText HTML](12) [PDF 1002KB](7)
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ObjectiveTo compare the teaching effect of online teaching method under the background of COVID-19 outbreak with traditional teaching method under no COVID-19 outbreak in health service management course.MethodsFifty-eight undergraduates of 2017 and 56 undergraduates of 2016 whose major is information management and information system in School of Health Management of Bengbu Medical College were taken as observation group and control group, respectively.Online teaching method was used under the background of COVID-19 outbreak in the observation group, while the control group adopted the traditional teaching method based on face-to-face classroom instruction during the no epidemic period.The effect of Evaluate the two groups were evaluated by the way of interview the students, design questionnaires, and analysis the course score.ResultsThe observation group is higher than the control group in terms of interest in curriculum, learning autonomy, teacher input, teaching method evaluation, etc., and lower than the control group in terms of classroom atmosphere, teacher answering speed, theoretical and practical ability training, teaching effect evaluation and teaching satisfaction(P < 0.01).Compared with traditional teaching mode, online teaching mode needed more extracurricular learning time.The scores of course in the control group (84.21±7.81) were higher than those in the observation group(69.92±6.01), the difference of which was statistically significant(t=10.92, P < 0.01).ConclusionsThe technical support, operation system and evaluation style of online teaching need to be further strengthened.Medical colleges and universities should seize the opportunity to deal with the challenge of COVID-19 outbreak.They should actively innovate new online teaching technical support means and design new teaching approach to accelerate the reform of education modernization, and constantly improve the quality and effect of medical education.
Intervention effects of passive somatic movement on ICU acquired weakness in respiratory failure patients treated with mechanical ventilation
ZHANG Qin, SUN Xing-dong, SONG Chang-chun, ZHANG Hai-li, ZOU Qi, YANG Bin
2020, 45(10): 1436-1438.   doi: 10.13898/j.cnki.issn.1000-2200.2020.10.033
[Abstract](31) [FullText HTML](14) [PDF 1001KB](0)
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ObjectiveTo investigate the clinical effects of passive somatic movement on ICU acquired weakness in respiratory failure patients treated with mechanical ventilation.MethodsSixty patients from ICU were divided into the control group and observation group(30 cases in each group).The control group was nursed with routine care, and the observation group was nursed with early passive somatic movement on the basis of routine care.The incidence rate of acquired weakness, independent functional status, mechanical ventilation time and length of hospital stay were compared between two groups.ResultsThe incidence rate of acquired weakness in observation group was lower than that in control group(P < 0.01).The duration of mechanical ventilation using ventilator and hospital stay in observation group were less than those in control group(P < 0.01).ConclusionsIn clinical practice, the passive somatic movement for respiratory failure patients treated with mechanical ventilation in ICU can effectively reduce the incidence rate of acquired weakness, shorten the duration of mechanical ventilation and hospital stay.
Effect of mixed mindfulness stress reduction training on the mental resilience and sleep quality in cancer patients
SUO Lei, LIU Yi-ying, XIONG Ling-ling, BAO Guo-hua, ZHANG Ya-jing
2020, 45(10): 1439-1442.   doi: 10.13898/j.cnki.issn.1000-2200.2020.10.034
[Abstract](31) [FullText HTML](15) [PDF 1025KB](1)
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ObjectiveTo explore the effects of "group + Dingding live" of mixed mindfulness-based stress reduction training on improving mental resilience and sleep quality of cancer patients.MethodsForty-six cancer patients were randomly divided into the observation group and control group.The control group was nursed with conventional care, and the observation group was nursed with four-week of mindfulness decompression groups face-to-face training and four-week of Dingding live online nursing intervention.The intervention level of mindfulness before and after intervention, mental resilience and sleep quality were compared between two groups.ResultsAfter intervention, the mindfulness score and mental resilience score in observation group were significantly higher than those before intervention, and the scores of mindfulness and mental resilience in observation group were significantly higher than those in control group(P < 0.01).After intervention, the total score of sleep quality and its factor scores(including the subjective sleep quality, sleep latency, sleep continuity, habitual sleep efficiency, use of sleep medicine and daytime dysfunction scores) in two groups decreased compared with before intervention, and the total score of sleep quality and its factor scores(including the subjective sleep quality, sleep latency, sleep continuity, habitual sleep efficiency, use of sleep medicine and daytime dysfunction scores) in observation group were lower than those in control group(P < 0.05 to P < 0.01).After intervention, the level of mindfulness was significantly positively correlated with mental resilience(P < 0.01), negatively correlated with sleep quality(P < 0.01), and the mental resilience was negatively correlated with sleep quality(P < 0.01).ConclusionsThe mixed mindfulness stress reduction training can effectively improve the mental resilience and sleep quality of cancer patients.
Analysis on the current situation of knowledge, attitude and practice of psychological assessment in clinical nurses, and its influencing factors
JIANG Min, HE Di, ZHANG Lei, ZHAO Yu-e, YUAN Fang
2020, 45(10): 1443-1448.   doi: 10.13898/j.cnki.issn.1000-2200.2020.10.035
[Abstract](34) [FullText HTML](16) [PDF 1053KB](1)
Abstract:
ObjectiveTo investigate the status of clinical nurses' knowledge, attitude and practice of psychological assessment, and analyze the influencing factors, so as to provide reference for nursing managers to strengthen relevant training and quality management.MethodsA total of 2 454 clinical nurses from a tertiary first-class hospital in Hubei province were selected as study subjects by convenience sampling method.The nurses were investigated using the self-designed questionnaire for psychological assessment of clinical nurse.ResultsA total of 2 453 valid questionnaires were collected.The total score of clinical nurses' knowledge, attitude and practice status of psychological assessment was (87.98±37.67), and the scores of knowledge dimension, attitude dimension and practice dimension were (84.28±18.67), (96.17±10.61) and (83.50±17.33), respectively.The results of multiple linear regression analysis showed that the total scores of clinical nurses' knowledge, attitude and practice status of psychological assessment in female, surgery department, ent, advanced department compared with the oncology department, and department carring out psychological assessment training and inpatient psychological assessment were the highest(P < 0.05 to P < 0.01).ConclusionsThe knowledge, attitude and practice level of psychological assessment of clinical nurses still need to be improved, and the nursing managers need to develop targeted psychological assessment training programs, and strengthen related quality management to improve the overall quality of nursing team.
Analysis of the influence factors on rehabilitation of Alzheimer's disease patients complicated with dysphagia
GUO Meng-jun
2020, 45(10): 1448-1450.   doi: 10.13898/j.cnki.issn.1000-2200.2020.10.036
[Abstract](30) [FullText HTML](15) [PDF 993KB](0)
Abstract:
ObjectiveTo explore the influence factors on rehabilitation of Alzheimer's disease patients complicated with dysphagia.MethodsThe swallowing training in 120 Alzheimer's disease patients complicated with dysphagia was implemented for 4 weeks.According to the recovery of dysphagia, the patients were divided into the good prognosis group and poor prognosis group.The influence factors on the recovery of swallowing function were analyzed using logistic regression analysis.ResultsThe ratios of patients with good curative effect and poor curative effect were 84.17% and 15.83%, respectively.The differences of the severity of swallowing disorder, feeding dependence and coordination between two groups were statistically significant(P < 0.01), and the differences of age, sex, education, diabetes and hypertension between two groups were not statistically significant(P>0.05).The degree of dysphagia(severity), feeding dependence(feeding), and visual and auditory impairment were related to the effects of swallowing rehabilitation training(P < 0.05 to P < 0.01).ConclusionsThe targeted swallowing rehabilitation training should be implemented according to the specific situation of the patients.
2020, 45(10): 1451-1453.   doi: 10.13898/j.cnki.issn.1000-2200.2020.10.037
[Abstract](43) [FullText HTML](22) [PDF 991KB](2)
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