压迫时间与压疮发生关系的实验研究

徐云侠; 胡守紫; 钟政荣; 刘玉芳; 王银娥

doi:10.13898/j.cnki.issn.1000-2200.2015.07.005

压迫时间与压疮发生关系的实验研究

1.
1. 蚌埠医学院第一附属医院神经内科, 安徽蚌埠 233004;
2.
2. 蚌埠医学院第一附属医院呼吸内科, 安徽蚌埠 233004;
3.
3. 蚌埠医学院第一附属医院检验科, 安徽蚌埠 233004;
4.
4. 蚌埠医学院第一附属医院急诊外科, 安徽蚌埠 233004

作者简介: 徐云侠(1975-),女,副主任护师.

通讯作者: 钟政荣, zrzhong@126.com ;

基金项目:
安徽省自然科学基金项目(1308085MH124)

安徽省教育厅自然科学研究重点项目(KJ2011A205)

蚌埠医学院自然科学研究项目(byky1231)

Experimental study on the relationship between compression time and pressure ulcer lesions

1.
1. Department of Neurology, The First Affiliated Hospital of Bengbu Medical College, Bengbu Anhui 233004, China;
2.
2. Department of Respiratory, The First Affiliated Hospital of Bengbu Medical College, Bengbu Anhui 233004, China;
3.
3. Department of Medical Laboratory, The First Affiliated Hospital of Bengbu Medical College, Bengbu Anhui 233004, China;
4.
4. Department of Emergency Surgery, The First Affiliated Hospital of Bengbu Medical College, Bengbu Anhui 233004, China

Corresponding author: ZHONG Zheng-rong, zrzhong@126.com ;

摘要: 目的:观察压迫不同时间后大鼠受压部位的皮肤形态及组织病理损伤情况。方法:将48只SD雄性大鼠分成6组,每组8只,对照组(A组)未压迫,其余5组分别对大鼠下肢关节压迫1 h(B组)、2 h(C组)、3 h(D组)、4 h(E组)和6 h(F组),每组间隔时间与压迫时间相同,总时间24 h,观察压迫后受压部位的皮肤和组织病理变化。结果:B、C、D、E、F组受压部位皮肤发红的大鼠分别有1、2、5、8和8只,D、E和F组大鼠受压部位皮肤发红数均明显多于A组(P结论:压迫时间超过2 h,大鼠受压部位皮肤和组织明显受损,随受压时间延长,皮肤受损更加严重。
- 压疮 /
- 压迫时间 /
- SD大鼠
Abstract: Objective:To observe the pathological damage of the skin and tissue of the compression parts after different time of compression in rats.Methods:Sixty-five Sprague-Dawley rats were randomly divided into the six groups(8 rats each group),which included the control group(group A,without compression),group B(compression for 1 h),group C(compression for 2 h),group D(compression for 3 h),group E(compression for 4 h) and group F(compression for 6 h).The time of compression and compression interval in all groups were the same,and the whole course was 24 h.The pathological damage of the skin and tissue of compression parts were observed after compression.Results:Erythema in 1 rat of group B,2 rats of group C,5 rats of group D,8 rats of group E and 8 rats group F were found.The number of erythema in group D,E and F were significantly more than that in group A(PConclusions:The damage of the skin and tissue of compression parts is obvious after 2 h of compression,skin damage is more serians when the pressure is prolonged.
- pressure ulcer /
- duration of pressure /
- SD rat

[1]	叶勉之,施春娜.溃疡贴治疗慢性阻塞性肺疾病并压疮患者的疗效观察[J].实用医学杂志,2013,29(2):336-337.
[2]	Reddy M,Gill SS,Rochon PA.Preventing pressure ulcers:a systematic review[J].JAMA,2006,296(8):974-984.
[3]	Scott JR,Gibran NS,Engrav LH,et al.Incidence and characteristics of hospitalized patients with pressure ulcers:State of Washington,1987 to 2000[J].Plast Reconstr Surg,2006,117(2):630-634.
[4]	Remsburg RE,Bennett RG.Pressure-relieving strategies for preventing and treating pressure sores[J].Clin Geriatr Med,1997,13(3):513-541.
[5]	Neilson J,Avital L,Willock J,et al.Using a national guideline to prevent and manage pressure ulcers[J].Nurs Manag(Harrow),2014,21(2):18-21.
[6]	Kottner J,Gefen A,Lahmann N.Weight and pressure ulcer occurrence:A secondary data analysis[J].Int J Nurs Stud,2011,48(11):1339-1348.
[7]	Duffin C.NICE issues guidance on pressure ulcer prevention and management[J].Nurs Stand,2014,28(35):10.
[8]	王艳艳,孙海琴,张纯瑜,等.压疮早期动物模型的制备及评价[J].护理学杂志,2010,25(14):1-5.
[9]	Bosboom EM,Bouten CV,Oomens CW,et al.Quantification and localisation of damage in rat muscles after controlled loading:a new approach to study the aetiology of pressure sores[J].Med Eng Phys,2001,23(3):195-200.
[10]	Jiang LP,Tu Q,Wang Y,et al.Ischemia-reperfusion injury-induced histological changes affecting early stage pressure ulcer development in a rat model[J].Ostomy Wound Manage,2011,57(2):55-60.
[11]	段晓侠,刘春芳,陈冬梅,等.局部注射胰岛素联合湿性敷料对糖尿病患者Ⅲ期压疮治疗的影响[J].蚌埠医学院学报,2014,39(9):1288-1290.
[12]	Cooper L,Vellodi C,Stansby G,et al.The prevention and management of pressure ulcers:summary of updated NICE guidance[J].J Wound Care,2015,24(4):179-181.
[13]	Sharp CA,White RJ.Pressure ulcer risk assessment:do we need a golden hour? [J].J Wound Care,2015,24(5):237.
[14]	任莉.泡沫敷料治疗骨科压疮18例效果观察[J].蚌埠医学院学报,2014,39(7):990-991.
[15]	庄嘉元,姜小鹰,宋继红.压迫间隔时间与皮肤压疮形成关系的实验研究[J].中华现代护理杂志,2010,16(4):373-376.

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压迫时间与压疮发生关系的实验研究

作者简介: 徐云侠(1975-),女,副主任护师.

通讯作者: 钟政荣, zrzhong@126.com ;

Experimental study on the relationship between compression time and pressure ulcer lesions

Corresponding author: ZHONG Zheng-rong, zrzhong@126.com ;

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压迫时间与压疮发生关系的实验研究

通讯作者: 钟政荣, zrzhong@126.com;

作者简介: 徐云侠(1975-),女,副主任护师.

English Abstract

Experimental study on the relationship between compression time and pressure ulcer lesions

Corresponding author: ZHONG Zheng-rong, zrzhong@126.com

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留言板

压迫时间与压疮发生关系的实验研究

作者简介: 徐云侠(1975-),女,副主任护师.

通讯作者: 钟政荣, zrzhong@126.com ;

Experimental study on the relationship between compression time and pressure ulcer lesions

Corresponding author: ZHONG Zheng-rong, zrzhong@126.com ;

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压迫时间与压疮发生关系的实验研究

通讯作者: 钟政荣, zrzhong@126.com;

作者简介: 徐云侠(1975-),女,副主任护师.

English Abstract

Experimental study on the relationship between compression time and pressure ulcer lesions

Corresponding author: ZHONG Zheng-rong, zrzhong@126.com

全文HTML

目录