子宫颈环形电切术治疗子宫颈上皮内瘤变83例疗效分析

陈燕

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子宫颈环形电切术治疗子宫颈上皮内瘤变83例疗效分析

陈燕

文章导航 > 蚌埠医学院学报 > 2012, 36 > 7: (813-815)

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子宫颈环形电切术治疗子宫颈上皮内瘤变83例疗效分析

陈燕

1.
淮南新华医院妇产科, 安徽淮南 232052

作者简介: 陈燕(1969-),女,副主任医师．

基金项目:

The effects of loop electrosurgical excision procedure on 83 patients with cerical intraepithelial neoplasia

CHEN Yan

1.
Department of Gynaecology and Obstetrics, Huainan Xinhua Hospital, Huainan Anhui 232052, China

摘要: 目的:探讨子宫颈环形电切术(LEEP)在诊治不同级别子宫颈上皮内瘤变(CIN)的效果、术后并发症及其预防措施和手术后标本的观察处理原则。方法:对妇科检查、细胞学、阴道镜活检初步诊断为CIN各期患者83例,采用环形电刀行子宫颈椎切术。观察手术前后组织病理诊断结果变化,对其疗效作回顾性分析。结果:术前、术后病理诊断一致57.8%;术后病理诊断级别下降37.4%,其中下降一级22.9%,下降两级12.1%,下降三级2.4%;术后病理诊断级别上升4.8%,其中上升一级3.6%,上升两级占1.2%。手术切缘阳性2例,其中CIN2、3各1例。术后3个月细胞学检查为CIN21例,其余均正常。术后子宫颈管解剖狭窄2例,术后2周大量出血1例。术后半年无CIN81例,治愈率97.6%;子宫颈CIN残留2例;第1年内复查发现CIN2持续1例。结论:LEEP是一种诊断、治疗CIN的较为理想的手段,只要掌握手术指征,规范手术步骤,注意术后病理观察,可获得满意疗效。
- 子宫疾病/外科手术 /
- 子宫颈上皮内瘤变 /
- 子宫颈环形电切术
Abstract: Objective:To explore the effects of loop electrosurgical excision procedure(LEEP) on cervical intraepithelial neoplasia(CIN) and prevent the postoperative complications and observe treatment principles for postoperarion specimens.Methods:Eighty-three patients with CIN were dignosed by gynecological check-up,cytology and vaginoscope biopsy,and operated with LEEP.The results of pathology diagnosis were compared before and after operation,and the curative effects were retrospectively analyzed.Results:The concordance rates of pathologic diagnosis were 57.8% before and after operation.The rates of descent of postoperative pathologic diagnosis were 37.4%,including dropping one grade in 22.9%,two grade in 12.1% and three grade in 2.4%.The rates of ascend of postoperative pathologic diagnosis were 4.8%,including rising one grade in 3.6%,two grade in 1.2%.Operation cut margin of 2 cases was postive reaction,including 1 case of CIN2 and 1 case of CIN3.Three months after operation,the results of cytology demonstrated CIN2 in 1 case,others were normal.The cervical stenosis in 2 cases at postoperation and massive haemorrhage in 1 case 2 weeks postoperation were found.No cases showed CIN for half year postoperation.The cure rates were 97.6%,and residual CIN in cervix were 2 cases.One 1 case of CIN2 were found after 1 year.Conclusions:LEEP is a ideal means in diagnosis and treatment of CIN.Mastering surgical indications,regulating surgical procedure and pay attention to the postoperative pathologic observation can obtain satisfied results.
- uterine disease /surgery /
- cervical intraepithelial neoplasia /
- loop electrosurgical excision procedure

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子宫颈环形电切术治疗子宫颈上皮内瘤变83例疗效分析

陈燕

作者简介: 陈燕(1969-),女,副主任医师．

1. 淮南新华医院妇产科, 安徽淮南 232052

收稿日期: 2011-11-28
网络出版日期: 2012-07-15

基金项目:

关键词:

摘要: 目的:探讨子宫颈环形电切术(LEEP)在诊治不同级别子宫颈上皮内瘤变(CIN)的效果、术后并发症及其预防措施和手术后标本的观察处理原则。方法:对妇科检查、细胞学、阴道镜活检初步诊断为CIN各期患者83例,采用环形电刀行子宫颈椎切术。观察手术前后组织病理诊断结果变化,对其疗效作回顾性分析。结果:术前、术后病理诊断一致57.8%;术后病理诊断级别下降37.4%,其中下降一级22.9%,下降两级12.1%,下降三级2.4%;术后病理诊断级别上升4.8%,其中上升一级3.6%,上升两级占1.2%。手术切缘阳性2例,其中CIN2、3各1例。术后3个月细胞学检查为CIN21例,其余均正常。术后子宫颈管解剖狭窄2例,术后2周大量出血1例。术后半年无CIN81例,治愈率97.6%;子宫颈CIN残留2例;第1年内复查发现CIN2持续1例。结论:LEEP是一种诊断、治疗CIN的较为理想的手段,只要掌握手术指征,规范手术步骤,注意术后病理观察,可获得满意疗效。

English Abstract

The effects of loop electrosurgical excision procedure on 83 patients with cerical intraepithelial neoplasia

CHEN Yan

1. Department of Gynaecology and Obstetrics, Huainan Xinhua Hospital, Huainan Anhui 232052, China

Received Date: 2011-11-28
Available Online: 2012-07-15

Abstract: Objective:To explore the effects of loop electrosurgical excision procedure(LEEP) on cervical intraepithelial neoplasia(CIN) and prevent the postoperative complications and observe treatment principles for postoperarion specimens.Methods:Eighty-three patients with CIN were dignosed by gynecological check-up,cytology and vaginoscope biopsy,and operated with LEEP.The results of pathology diagnosis were compared before and after operation,and the curative effects were retrospectively analyzed.Results:The concordance rates of pathologic diagnosis were 57.8% before and after operation.The rates of descent of postoperative pathologic diagnosis were 37.4%,including dropping one grade in 22.9%,two grade in 12.1% and three grade in 2.4%.The rates of ascend of postoperative pathologic diagnosis were 4.8%,including rising one grade in 3.6%,two grade in 1.2%.Operation cut margin of 2 cases was postive reaction,including 1 case of CIN2 and 1 case of CIN3.Three months after operation,the results of cytology demonstrated CIN2 in 1 case,others were normal.The cervical stenosis in 2 cases at postoperation and massive haemorrhage in 1 case 2 weeks postoperation were found.No cases showed CIN for half year postoperation.The cure rates were 97.6%,and residual CIN in cervix were 2 cases.One 1 case of CIN2 were found after 1 year.Conclusions:LEEP is a ideal means in diagnosis and treatment of CIN.Mastering surgical indications,regulating surgical procedure and pay attention to the postoperative pathologic observation can obtain satisfied results.