盆腔孤立性纤维瘤1例并文献复习

丁银满; 王正权; 石小军; 诸禹平

doi:10.13898/j.cnki.issn.1000-2200.2015.04.025

盆腔孤立性纤维瘤1例并文献复习

1. 安徽省宣城市人民医院泌尿外科, 242000;
2. 安徽省立医院泌尿外科, 安徽合肥 230000

作者简介: 丁银满(1972-),男,副主任医师.

中图分类号: R730.262

Pelvic solitary fibrous tumor in 1 case and literature review

1. Department of Urology, The People's Hospital of Xuancheng, Xuancheng Anhui 242000;
2. Department of Urology, Anhui Provincial Hospital, Hefei Anhui 230000, China
CLC number: R730.262

摘要: 目的:探讨盆腔孤立性纤维瘤的临床和病理特征、诊断和鉴别诊断、治疗以及预后。方法:对1例盆腔孤立性纤维瘤的临床和病理、影像学表现、诊断和鉴别诊断及治疗方式等进行探讨。结果:手术标本肉眼观:肿瘤包膜完整,表面光滑,切面灰白,质嫩;镜下观:主要由梭形细胞组成,肿瘤细胞丰富伴轻度异型,核染色质粗,核分裂像分布不均匀,由细胞致密区和疏松区交替无特定结构排列,灶性区可见坏死,低度恶性,间质血管较丰富,细胞间可见大量胶原纤维;免疫组织化学:CD34+,CD31+,Bcl-2凋亡蛋白±,细胞增殖相关抗原20%+,细胞角蛋白-,钙视网膜蛋白-,CD99抗原-,肌间线蛋白-,p53-,S-100+,平滑肌肌动蛋白-,波形蛋白+,WT-1蛋白-。结论:孤立性纤维性肿瘤无特异性临床表现,诊断主要依据病理形态学特征和特异性标志物的免疫组织化学检测;需与其他梭形细胞瘤鉴别;首选手术治疗,术后需进行密切随访。
- 纤维瘤 /
- 盆腔 /
- 孤立性
Abstract: Objective:To investigate the clinical and pathological features, diagnosis and differential diagnosis, treatment and prognosis of pelvic solitary fibrous tumor.Methods:The clinical and pathological features, diagnosis and differential diagnosis, treatment and prognosis of pelvic solitary fibrous tumor in a case were explored.Results:Complete capsule, smooth surface, gray cut-off and soft texture of tumor were observed under naked eye.Under microscopy, the tumor was mainly composed of spindle cells, mild dysplasia, coarse nuclear chromatin and uneven mitosis in tumor cells were detected, the tumor cells were alternatively arranged by hypercellularity and hypocellularity, and the necrosis with low potential malignancy, rich interstitial blood vessels and a large number of collagen fibers were found.The CD34+, CD31+, B-cell lymphoma 2±, antigen Ki-67 20%+, pan-cytokeratin antibody-, Calretinin-, CD99-, Desmin-, MC-, p53-, S-100+, smooth muscle actin-, Vimentin+ and protein WT-1- were identified by immunohistochemistry.Conclusions:The solitary fibrous tumor has not specific clinical manifestations, the dignosis of which depends on the pathological features and detection of specific markers by immunohistochemistry.The tumor need to be identified with other spindle cell tumor, treated with operation and followed up after operation.
- fibrous tumor /
- pelvic cavity /
- solitary

[1]	Rodriguez F, Scheithaue BW, Ockne DL, et al.Solitary fibrous tumor of the cerebellopontine angle with salivary gland heterotopia[J].Am J Surg Pathol, 2004, 28(1):139-142.
[2]	Ekici Y, Uysal S, Guven G, et al.Solitary fibrous tumor of the lesser omentum:report of a rare case[J].Turk J Gastroenterol, 2010, 21(4):464-466.
[3]	Hinohara M, Kohda E, Kobayashi S, et al.Malignant solitary fibrous tumor of the pleura:two cases and review of the literature[J].Nihon Igaku Hoshasen Gakkai Zasslli, 2000, 60(8):428-433.
[4]	Poyraz A, Kilic D, Hatipoglu A, et al.Pedunculated solitary fibrous tumors arising from the pleural[J].Monaldi Arch Chest Dis, 2006, 65(3):165-168.
[5]	Suehisa H, Yamashita M, Komori E, et al.Solitary fibrous tumor of the mediastinum[J].Gen Thorac Cardiovasc Surg, 2010, 58(4):205-208.
[6]	Kalebi AY, Hale MJ, Wong ML, et al.Surgically cured hypoglycemia secondary to pleural solitary fibrous tumour:case report and update review on the Doege-Potter syndrome[J].Cardiothorac Surg, 2009, 4(45):1-8.
[7]	Tateshi U, Nishinare H, Morikawa T, et al.solitary fibrous tumor of the pleura:MR appearance and enhancement pattern[J].J Comput Assist Tumogr, 2002, 26(2):174-179.
[8]	Hasegawa T, Matsuno Y, Shimoda T, et al.Extrathoracic solitary fibrous tumors:their histological Variability and potentially aggressive behavjor[J].Hum Pathol, 1999, 30(12):1464-1473.
[9]	Vallat-Decouvelaere AV, Dry SM, Fletcher CD.Atypical and malignant solitary fibrous tumours in extrathoracic locations:evidence of their comparability to intra-thoracic tumours[J].Am J Surg Pathol, 1998, 22(12):1501-1511.
[10]	Tanaka M, Sawai H, Okada Y, et al.Malignant solitary fibrous tumor originating from the peritoneum and review of the literature[J].Med Sci Monit, 2006, 12(10):CS95-CS98.
[11]	Weiss SW, Goldblum JR.Soft tissue tumors[M].St Louis:Mosby Elsevier Press, 2008:1129-1131.
[12]	Cox DP, Daniels T, Jordan RC.Solitary fibrous tumor of the head andneck[J].Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 2010, 10(1):79-84.
[13]	Mosquera JM, Fletcher CD.Expanding the spectrum of malignant progression in solitary fibrous tumors:a study of 8 cases with a discrete anaplastic component:is this dedifferentiated SFT[J].Am J Surg Pathol, 2009, 33(9):1314-1321.
[14]	Ambrosini-Spaltro A, Eusebi V.Meningeal hemangiopericytomas and hemangiopericytoma/solitary fibrous tumors of extracranial soft tissues:a comparison[J].Virchows Arch, 2010, 456(4):343-354.
[15]	Ferreira EJ, Diaz JA.Solitary fibrous tumour of the pleum[J].Rev Chilena Cirugia, 2008, 60(2):465-472.
[16]	Gengler C, Guillou L.Solitary fibrous tumour and haemangiopericytoma:evolution of a concept[J].Histopathology, 2006, 48(1):63-74.
[17]	Pak PS, Yanagawa J, Abtin F, et al.Surgical management of endobronchial solitary fibrous tumors[J].Ann Thorac Surg, 2010, 90(2):659-661.
[18]	Insabato L, Siano M, Somma A, et al.Extrapleural solitary fibrous tumor:a clinicopathologic study of 19 cases[J].Int J Surg Pathol, 2009, 17(3):250-254.
[19]	Peixoto Canejo I.Peritoneal solitary fibrous tumour(SFT):long-term survival of recurrent and metastasised SFT treated with cytoreductive surgery and intraperitoneal chemotherapy[J].Clin Transl Oncol, 2009, 11(4):250-252.

[1]	肖潇 , 肖后生 , 杨杰 . 孤立性纤维性肿瘤6例超声诊断及病理分析. 蚌埠医学院学报, 2013, 37(10): 1334-1337.
[2]	朱博 , 张兰玲 , 杜丹丽 , 谢群 , 王萍 . 子宫纤维瘤病1例临床病理分析及文献复习. 蚌埠医学院学报, 2012, 36(3): 271-273.
[3]	法文 , 王帅 , 杨振中 . 青春期前型外阴纤维瘤临床病理分析. 蚌埠医学院学报, 2012, 36(5): 544-547.
[4]	范建灵 , 张宁芝 , 肖红 , 宛杨 , 张静 , 王晖 . 腹腔镜下盆腔腹膜阴道成形术的临床应用. 蚌埠医学院学报, 2008, 33(4): 456-457.
[5]	朱松青 . 宫颈癌根治术后并发症分析. 蚌埠医学院学报, 2014, 39(8): 1089-1091.
[6]	刘啸峰 , 丁玉芹 , 何德明 , 周建军 . 腹内型侵袭性纤维瘤病多排螺旋CT和MRI诊断价值. 蚌埠医学院学报, 2015, 40(2): 238-241. doi: 10.13898/j.cnki.issn.1000-2200.2015.02.035
[7]	张根山 , 徐恒光 , 张旭 , 倪敬中 , 段中宁 . 内镜下鼻咽血管纤维瘤切除术前选择性供血动脉栓塞6例临床分析. 蚌埠医学院学报, 2009, 34(3): 243-245.
[8]	甘怀勇 , 张琼 , 李涤臣 . 盆腔复发性侵袭性血管黏液瘤1例报告并文献复习. 蚌埠医学院学报, 2013, 37(5): 549-551.
[9]	李小祺 , 崔培元 . 肝脏孤立性纤维性肿瘤1例并文献复习. 蚌埠医学院学报, 2016, 41(11): 1492-1495. doi: 10.13898/j.cnki.issn.1000-2200.2016.11.029
[10]	滕丽娜 . 盆腔囊性肿块的超声鉴别诊断. 蚌埠医学院学报, 2006, 31(4): 415-416.
[11]	钟辉 , 宋曾光 , 刘运贤 , 吴小龙 . 神经纤维瘤病1型相关的胃肠道间质瘤. 蚌埠医学院学报, 2010, 35(10): 1012-1014,1017.
[12]	吴礼高 , 刘德纯 . 丛状神经纤维瘤12例临床病理分析. 蚌埠医学院学报, 2007, 32(2): 156-158.
[13]	汪向明 , 马莉 , 蔡兆根 , 于东红 . 以阴道出血为首发症状的盆腔卵黄囊瘤1例. 蚌埠医学院学报, 2006, 31(1): 110-110.
[14]	李君君 , 韦炜 . 肾窦孤立性占位1例. 蚌埠医学院学报, 2020, 45(4): 561-562. doi: 10.13898/j.cnki.issn.1000-2200.2020.04.042
[15]	李君君 , 韦炜 . 肾窦孤立性占位1例. 蚌埠医学院学报, 2020, 45(4): 560-561. doi: 10.13898/j.cnki.issn.1000-2200.2020.04.037
[16]	吴江宏 . 经乳晕弧形切口切除术治疗乳房纤维瘤对乳房损伤及术后乳房外观满意率的影响. 蚌埠医学院学报, 2017, 42(12): 1624-1626. doi: 10.13898/j.cnki.issn.1000-2200.2017.12.016
[17]	徐文彬 , 颜太琼 . 不同路径手术治疗对乳房纤维瘤病人预后与乳头乳晕皮肤感觉的影响. 蚌埠医学院学报, 2018, 43(7): 874-876,881. doi: 10.13898/j.cnki.issn.1000-2200.2018.07.009
[18]	俞保柱 , 李庆文 , 王成勇 , 张家俊 . 膀胱炎性肌纤维母细胞瘤4例报道及文献复习. 蚌埠医学院学报, 2009, 34(12): 1073-1075.
[19]	韦明 . 腹腔镜微创手术和传统开腹手术在盆腔炎性包块中的疗效比较. 蚌埠医学院学报, 2018, 43(7): 925-927. doi: 10.13898/j.cnki.issn.1000-2200.2018.07.024
[20]	吴静 , 齐少恒 , 王洪飞 . 孤立性蝶窦疾病12例临床分析. 蚌埠医学院学报, 2017, 42(5): 648-650. doi: 10.13898/j.cnki.issn.1000-2200.2017.05.026

点击查看大图

计量

文章访问数: 3642
HTML全文浏览量: 480
PDF下载量: 149
被引次数: 0

姓名
邮箱
手机号码
标题
留言内容
验证码

留言板

盆腔孤立性纤维瘤1例并文献复习

作者简介: 丁银满(1972-),男,副主任医师.

Pelvic solitary fibrous tumor in 1 case and literature review

计量

盆腔孤立性纤维瘤1例并文献复习

作者简介: 丁银满(1972-),男,副主任医师.

English Abstract

Pelvic solitary fibrous tumor in 1 case and literature review

全文HTML

目录

留言板

盆腔孤立性纤维瘤1例并文献复习

作者简介: 丁银满(1972-),男,副主任医师.

Pelvic solitary fibrous tumor in 1 case and literature review

计量

出版历程

盆腔孤立性纤维瘤1例并文献复习

作者简介: 丁银满(1972-),男,副主任医师.

English Abstract

Pelvic solitary fibrous tumor in 1 case and literature review

全文HTML

目录