慢性阻塞性肺疾病患者认知功能与抑郁、焦虑及BODE指数的关系

袁娜娜; 陈余清

doi:10.13898/j.cnki.issn.1000-2200.2015.05.006

慢性阻塞性肺疾病患者认知功能与抑郁、焦虑及BODE指数的关系

蚌埠医学院第一附属医院呼吸与危重症医学科, 安徽呼吸系病临床基础省级实验室, 安徽蚌埠 233004

作者简介: 袁娜娜(1990-),女,硕士研究生.

基金项目:
蚌埠医学院研究生科研创新计划资助项目(Byycx1308)
中图分类号: R563.9

Cognitive impairment in chronic obstructive pulmonary disease and its relation to depression、anxiety and BODE index

Department of Respiratory and Critic Care Medicine, Anhui Clinical and Preclinical Key Laboratory of Respiratory Disease, The First Affiliated Hospital of Bengbu Medical College, Bengbu Anhui 233004, China
CLC number: R563.9

摘要: 目的:了解慢性阻塞性肺疾病(COPD)患者的认知功能状况,并探讨其认知功能和抑郁、焦虑及BODE指数的关系。方法:选取COPD患者53例(COPD组)和同期健康体检者49名(对照组),分别进行认知功能及抑郁、焦虑状态测定,比较2组认知功能及抑郁、焦虑差异。并对COPD组进行BODE指数测定,分析COPD组认知功能和抑郁、焦虑及BODE指数的关系。结果:COPD组认知功能评分较对照组明显下降(P<0.01),COPD组抑郁、焦虑评分均较对照组明显升高(P<0.01)。将COPD组按照认知功能评分(24分为界值)分为认知正常组和认知障碍组,认知障碍组抑郁、焦虑及BODE指数评分均较认知正常组增高(P<0.01),COPD组认知功能与焦虑、抑郁及BODE指数总分均呈负相关关系(P<0.01)。结论:COPD患者认知功能和抑郁、焦虑及BODE指数密切相关。
- 肺疾病,阻塞性 /
- 认知障碍 /
- 抑郁 /
- 焦虑 /
- BODE指数
Abstract: Objective: To investigate the relationships between cognitive function,depression,anxiety and BODE index(including body mass index,airflow obstruction,dyspnea and exercise capacity index) in patients with chronic obstructive pulmonary disease(COPD).Methods: In the cross-sectional study method,53 patients diagnosed as COPD were evaluated for cognitive function,depression,anxiety and BODE scores,49 normal health controls were evaluated for cognitive function,depression,anxiety scores.The differences of COPD group and control group in cognitive function and depression,anxiety were analyzed.The relationship between cognitive function and depression,anxiety and BODE index in COPD group were analyzed.Results: Compared with control group,cognitive function in COPD group decreased significantly(P<0.01)and the depression and anxiety scores of COPD group all increased significantly(P<0.01).Compared with COPD patients without cognitive impairment,the scores of depression,anxiety and BODE index of COPD patients with cognitive impairment all increased significantly(P<0.01).The cognitive function was negatively correlated with depression,anxiety and BODE index scores in COPD group(P<0.01)Conclusions: Cognitive function and depression,anxiety and BODE index in COPD group were closely related.
- disease,obstructive pulmonary /
- cognitive impairment /
- depression /
- anxiety /
- BODE index

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慢性阻塞性肺疾病患者认知功能与抑郁、焦虑及BODE指数的关系

作者简介: 袁娜娜(1990-),女,硕士研究生.

Cognitive impairment in chronic obstructive pulmonary disease and its relation to depression、anxiety and BODE index

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慢性阻塞性肺疾病患者认知功能与抑郁、焦虑及BODE指数的关系

作者简介: 袁娜娜(1990-),女,硕士研究生.

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Cognitive impairment in chronic obstructive pulmonary disease and its relation to depression、anxiety and BODE index

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慢性阻塞性肺疾病患者认知功能与抑郁、焦虑及BODE指数的关系

作者简介: 袁娜娜(1990-),女,硕士研究生.

Cognitive impairment in chronic obstructive pulmonary disease and its relation to depression、anxiety and BODE index

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慢性阻塞性肺疾病患者认知功能与抑郁、焦虑及BODE指数的关系

作者简介: 袁娜娜(1990-),女,硕士研究生.

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Cognitive impairment in chronic obstructive pulmonary disease and its relation to depression、anxiety and BODE index

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