大面积脑梗死伴脑水肿患者的定量脑电图检测分析

王新一; 蔡增林; 徐丙超; 李路明; 周晓梅

doi:10.13898/j.cnki.issn.1000-2200.2015.12.010

留言板

尊敬的读者、作者、审稿人, 关于本刊的投稿、审稿、编辑和出版的任何问题, 您可以本页添加留言。我们将尽快给您答复。谢谢您的支持!

姓名
邮箱
手机号码
标题
留言内容
验证码

大面积脑梗死伴脑水肿患者的定量脑电图检测分析

王新一 , 蔡增林 , 徐丙超 , 李路明 , 周晓梅

文章导航 > 蚌埠医学院学报 > 2015, 40 > 12: (1646-1648)

引用本文:

Citation:

大面积脑梗死伴脑水肿患者的定量脑电图检测分析

江苏省连云港市第一人民医院神经内科, 222000

作者简介: 王新一(1970-),男,副主任医师.

中图分类号: R743.33

Quantitative analysis of electroencephalogram in patients with massive cerebral infarction complicated with cerebral edema

Department of Neurology, The First People's Hospital of Lianyungang, Lianyungang Jiangsu 222000, China
CLC number: R743.33

摘要: 目的:探讨定量脑电图(qEEG)在大面积脑梗死伴脑水肿患者中的监护应用价值.方法:将大面积脑梗死伴脑水肿30例老年患者作为观察组,选择同期体检老年人30名为对照组,采用Bio-Logic脑电图仪分别检测患者发病6 h内(T₁)、24 h(T₂)、72 h(T₃)、168 h(T₄)的qEEG,检测(δ+θ)波与(α+β)波的比率(DTABR)以及颅内脑水肿体积和美国国立卫生研究院卒中量表(NIHSS)评分,比较在不同病程阶段的变化.结果:入院后观察组DTABR高于对照组(P<0.01);观察组患者治疗中死亡5例,各个病程阶段之间DTABR、脑水肿体积和NIHSS评分的比较结果显示,T₁与T₂差异均无统计学意义(P>0.05),T₃D TABR和脑水肿体积均多于T₁和T₂(P<0.05~P<0.01),而T₄ DTABR脑水肿体积和NIHSS评分均明显少于T₁、T₂与T₃.观察组治愈患者DTABR和NIHSS评分均低于未愈患者(P<0.05~P<0.01).结论:qEEG可客观有效地评价大面积脑梗死伴脑水肿患者脑功能情况,有望成为神经内科重症监护病房床边脑功能评价的重要方法.
- 脑梗死 /
- 脑水肿 /
- 定量脑电图
Abstract: Objective:To investigate the monitoring value of quantitative electroencephalogram(qEEG) in the patients with massive cerebral infarction complicated with cerebral edema.Methods:Thirty elderly patients with massive cerebral infarction complicated with cerebral edema and 30 examination elderly people were divided into the observation group and control group.The qEEG detected by the Bio-Logic electroencephalograph,DTABR,intracranial brain edema volume and National Institutes of Health Stroke Scale(NIHSS) in all patients were compared and analyzed within 6 h(T₁),24 h(T₂),72 h(T₃) and 168 h(T₄) of the onset of disease.Results:The DTABR in observation group was higher than that in control group(P<0.01),5 cases in observation group died during the treatment.The results of DTABR,cerebral edema volume and NIHSS score at each stage showed that the difference of which between T₁ and T₂ was not statistically significant(P>0.05).The change trends of DTABR index,NIHSS score and cerebral edema volume were similar,which arrived at the peak after 72 h,and began to decrease with the course of disease alleviating.The DTABR of the cure patients in observation group increased from T₁ to T₃,arrived at the peak,and gradually began to decrease from T₃ to T₄,while the declining trend of DTABR at T₃ and T₄ in the unhealed patients was not found.Conclusions:The qEEG can objectively and effectively evaluate the brain function in the patients with massive cerebral infarction complicated with cerebral edema,which can be expected to become an important bedside assessment means of brain function in neurological intensive care unit.
- cerebral infarction /
- cerebral edema /
- quantitative electroencephalogram

[1]	Mettler FA Jr,Huda W,Yoshizumi TT,et al.Effective doses in radiology and diagnostic nuclear medicine:a catalog[J].Radiology,2008,248(1):254-263.
[2]	Friedman D,Claassen J.Quantitative EEG and cerebral ischemia[J].Clin Neurophysiol,2010,121(10):1707-1708.
[3]	赵经纬,张运周,宿英英.定量脑电图与脑卒中[J].中华老年脑心血管病杂志,2012,14(7):774-777.
[4]	Leon-Carrion J,Martin-Rodriguez JF,Damas-Lopez J,et al.Brain function in the minimally conscious state:a quantitative neurophysiological study[J].Clin Neurophysiol,2008,119(7):1506-1514.
[5]	Sheorajpanday RV,Nagels G,Weeren AJ,et al.Quantitative EEG in ischemic stroke:Correlation with infarct volume and functional status in posterior circulation and lacunar syndromes[J].Clin Neurophysiol,2011,122(5):884-890.
[6]	Finnigan SP,Walsh M,Rose SE,et al.Quantitative EEG indices of subacute ischaemic stroke correlate with clinical outcomes[J].Clin Neurophysiol,2007,118(11):2525-2532.
[7]	田歌,潘速跃,吴永明,等.定量脑电图对大面积大脑中动脉供血区梗死患者预后的预测价值[J].国际脑血管病杂志,2012,20(3):170-176.

[1]	樊宝华 , 王光宇 , 张文川 . 脑出血急性期血小板反应蛋白、基质金属蛋白酶与脑血肿及脑水肿的关系. 蚌埠医学院学报, 2020, 45(7): 864-867. doi: 10.13898/j.cnki.issn.1000-2020.07.006
[2]	曹永胜 , 方经宏 , 朱光宇 . 急性硬膜下血肿伴脑水肿的手术治疗探讨. 蚌埠医学院学报, 2009, 34(1): 40-41.
[3]	熊建忠 , 易飞 , 揭文妙 . 头孢曲松钠预处理对大鼠缺血再灌注损伤后脑水肿的影响. 蚌埠医学院学报, 2013, 37(4): 389-391.
[4]	李明 , 廖环 , 李政卫 , 许峰峰 , 肖丽鸿 , 丁强 , 刘信龙 , 徐正平 , 杨冰 . 高压氧治疗对脑膜瘤术后脑水肿及其所致神经功能缺损的实效性评价. 蚌埠医学院学报, 2016, 41(2): 188-190. doi: 10.13898/j.cnki.issn.1000-2200.2016.02.016
[5]	许娟娟 , 许力 , 刘杨 , 屈洪党 . 血清铁蛋白与脑出血后脑水肿的相关性研究. 蚌埠医学院学报, 2016, 41(9): 1142-1143,1146. doi: 10.13898/j.cnki.issn.1000-2200.2016.09.007
[6]	汪再生 . 小脑梗死18例临床分析. 蚌埠医学院学报, 2011, 36(8): 867-868.
[7]	岳喜龙 . 早期微创穿刺碎引流术治疗中小量基底核脑出血效果分析. 蚌埠医学院学报, 2015, 40(3): 369-371. doi: 10.13898/j.cnki.issn.1000-2200.2015.03.025
[8]	汪彤彤 , 郑德群 . 外伤性脑梗死28例临床诊治分析. 蚌埠医学院学报, 2010, 35(12): 1248-1249.
[9]	赵兴利 . 进展性脑梗死患者预后相关因素分析. 蚌埠医学院学报, 2014, 39(10): 1370-1372,1375.
[10]	赵良举 . 血栓弹力图在预测腔隙性脑梗死发展为进展性脑梗死的价值. 蚌埠医学院学报, 2019, 44(5): 645-648. doi: 10.13898/j.cnki.issn.1000-2200.2019.05.023
[11]	李有中 , 郑重 , 谢康 . 动脉粥样硬化性脑梗死病人胱抑素C、同型半胱氨酸、超敏C反应蛋白和D-二聚体联合检测的临床意义. 蚌埠医学院学报, 2018, 43(5): 589-591. doi: 10.13898/j.cnki.issn.1000-2200.2018.05.007
[12]	李强 , 刘晓林 , 张郁文 . 脑梗死患者循环活化血小板FIB-R的检测及其临床意义. 蚌埠医学院学报, 2005, 30(6): 505-507.
[13]	辛胜利 . 小剂量低分子肝素钠治疗急性脑梗死疗效观察. 蚌埠医学院学报, 2006, 31(1): 70-71.
[14]	汪国胜 , 钟平 . 急性脑梗死患者C反应蛋白水平的变化及其临床意义. 蚌埠医学院学报, 2006, 31(5): 517-518.
[15]	冯敏 , 张友好 . 脑梗死与血脂、血糖、血尿酸水平的关系探讨. 蚌埠医学院学报, 2007, 32(4): 429-430.
[16]	徐从军 , 贺斌 . 中青年人非创伤急性脑梗死的病因与临床特点分析. 蚌埠医学院学报, 2009, 34(5): 424-426.
[17]	汪国胜 , 钟平 . 脑梗死急性期血清白介素-6的变化及其临床意义. 蚌埠医学院学报, 2008, 33(3): 306-307.
[18]	蒋海华 , 时恒屏 , 徐艳 . 心理干预对康复期脑梗死患者认知功能的影响. 蚌埠医学院学报, 2010, 35(1): 87-89.
[19]	张树宝 , 颜广林 , 张波 , 贺小平 . 外伤性腔隙性脑梗死的病理因素及CT相关分析. 蚌埠医学院学报, 2010, 35(1): 64-65.
[20]	黄海浪 . 血栓通注射液治疗脑梗死临床疗效观察. 蚌埠医学院学报, 2010, 35(6): 609-611.

点击查看大图

计量

文章访问数: 3743
HTML全文浏览量: 470
PDF下载量: 142
被引次数: 0

大面积脑梗死伴脑水肿患者的定量脑电图检测分析

作者简介: 王新一(1970-),男,副主任医师.

江苏省连云港市第一人民医院神经内科, 222000

收稿日期: 2015-02-08

关键词:

摘要: 目的:探讨定量脑电图(qEEG)在大面积脑梗死伴脑水肿患者中的监护应用价值.方法:将大面积脑梗死伴脑水肿30例老年患者作为观察组,选择同期体检老年人30名为对照组,采用Bio-Logic脑电图仪分别检测患者发病6 h内(T₁)、24 h(T₂)、72 h(T₃)、168 h(T₄)的qEEG,检测(δ+θ)波与(α+β)波的比率(DTABR)以及颅内脑水肿体积和美国国立卫生研究院卒中量表(NIHSS)评分,比较在不同病程阶段的变化.结果:入院后观察组DTABR高于对照组(P<0.01);观察组患者治疗中死亡5例,各个病程阶段之间DTABR、脑水肿体积和NIHSS评分的比较结果显示,T₁与T₂差异均无统计学意义(P>0.05),T₃D TABR和脑水肿体积均多于T₁和T₂(P<0.05~P<0.01),而T₄ DTABR脑水肿体积和NIHSS评分均明显少于T₁、T₂与T₃.观察组治愈患者DTABR和NIHSS评分均低于未愈患者(P<0.05~P<0.01).结论:qEEG可客观有效地评价大面积脑梗死伴脑水肿患者脑功能情况,有望成为神经内科重症监护病房床边脑功能评价的重要方法.

English Abstract

Quantitative analysis of electroencephalogram in patients with massive cerebral infarction complicated with cerebral edema

Department of Neurology, The First People's Hospital of Lianyungang, Lianyungang Jiangsu 222000, China

Received Date: 2015-02-08

Abstract: Objective:To investigate the monitoring value of quantitative electroencephalogram(qEEG) in the patients with massive cerebral infarction complicated with cerebral edema.Methods:Thirty elderly patients with massive cerebral infarction complicated with cerebral edema and 30 examination elderly people were divided into the observation group and control group.The qEEG detected by the Bio-Logic electroencephalograph,DTABR,intracranial brain edema volume and National Institutes of Health Stroke Scale(NIHSS) in all patients were compared and analyzed within 6 h(T₁),24 h(T₂),72 h(T₃) and 168 h(T₄) of the onset of disease.Results:The DTABR in observation group was higher than that in control group(P<0.01),5 cases in observation group died during the treatment.The results of DTABR,cerebral edema volume and NIHSS score at each stage showed that the difference of which between T₁ and T₂ was not statistically significant(P>0.05).The change trends of DTABR index,NIHSS score and cerebral edema volume were similar,which arrived at the peak after 72 h,and began to decrease with the course of disease alleviating.The DTABR of the cure patients in observation group increased from T₁ to T₃,arrived at the peak,and gradually began to decrease from T₃ to T₄,while the declining trend of DTABR at T₃ and T₄ in the unhealed patients was not found.Conclusions:The qEEG can objectively and effectively evaluate the brain function in the patients with massive cerebral infarction complicated with cerebral edema,which can be expected to become an important bedside assessment means of brain function in neurological intensive care unit.