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转移相关蛋白2对结直肠癌病人预后判断的价值

杨尊敬 杜先玲

引用本文:
Citation:

转移相关蛋白2对结直肠癌病人预后判断的价值

    作者简介: 杨尊敬(1982-),男,主治医师.
  • 中图分类号: R735.3

The value of metastasis associated protein 2 expression level in the prediction of the prognosis of patients with colorectal cancer

  • CLC number: R735.3

  • 摘要: 目的:探讨转移相关蛋白2(MTA2)作为结直肠癌病人疾病预后标志物的价值。方法:采用组织芯片方法及免疫组织化学方法检测结直肠癌组织和临近非肿瘤组织中MTA2表达情况,采集病人随访信息,统计分析MTA2表达与病人临床病理学特征间关系。结果:与临近非肿瘤组织相比,结直肠癌组织中MTA2表达上调(P<0.05)。结直肠癌组织中MTA2表达是疾病独立相关因素,与病人疾病预后不良密切相关(P<0.01)。结论:MTA2与结直肠癌病人预后密切相关,作为结直肠癌病人疗效评价和预后的分子标志物具有较高价值。
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  • 收稿日期:  2016-04-18

转移相关蛋白2对结直肠癌病人预后判断的价值

    作者简介: 杨尊敬(1982-),男,主治医师.
  • 湖北省恩施州中心医院 肿瘤放化疗科, 445000

摘要: 目的:探讨转移相关蛋白2(MTA2)作为结直肠癌病人疾病预后标志物的价值。方法:采用组织芯片方法及免疫组织化学方法检测结直肠癌组织和临近非肿瘤组织中MTA2表达情况,采集病人随访信息,统计分析MTA2表达与病人临床病理学特征间关系。结果:与临近非肿瘤组织相比,结直肠癌组织中MTA2表达上调(P<0.05)。结直肠癌组织中MTA2表达是疾病独立相关因素,与病人疾病预后不良密切相关(P<0.01)。结论:MTA2与结直肠癌病人预后密切相关,作为结直肠癌病人疗效评价和预后的分子标志物具有较高价值。

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