|
[1]
|
Glover DM, Leibowitz MH, McLean DA, et al. Mutations inaurora prevent centrosome separation leading to the formation ofmonopolar spindles〕].Ce11,1995,81 (1):95105 |
|
[2] Miyoshi Y, Iwao K, L,gawa C, et al. Association of centrosomalkinase STK15/BTAK mRNA expression with chromosomalinstahilitv in human breast cancer.Int J Cancer, 2001，92(3 ):370373 |
|
[3] Bischoff JH, Anderson L, Zhu Y, et al. A homologue of Drosophilaaurora kinase is oncogenic and amplified in human colorectalCancer[J].Embo.J,1998,17(7):30523065. |
|
[4] Bolanosfiarcia VM. Aurora kinases [J].Int J Biochem Cell Biol 2005,37(8):1672-1577. |
|
[5] Sugimoto K, Lrano T, Zushi H, et al. Molecular dynamics ofAurora-A kinase in living mitotic cells simultaneously visualizedwith histone H3 and nuclear membrane protein importinalpha[J].Cell Struct Funct,2002,27 (6):457-467. |
|
[6] LiX，Sakashita G, Matsuzaki H, et al. Direct association with innercentromere protein(INCENP) activates the novel chromosomalpassenger protein Aurora[J].J Biol Chem, 2004, 279 (45):47201-47211. |
|
[7] Orr-WeaverTL, Weinberg KA. A checkpoint on the road to cancer[J].Nature,1998,392(6673):223-224. |
|
[8] D' Assoro AB, Lingle WL, Salisbury JL，et al. Centrosomeamplification and the development of cancer.Oncogene,2002,21(40):6146-6153. |
|
[9] Katavama H, Brinklev W R, Sen S, et al. The aurora kinases: rolein cell transformation and tumorigenesis [J].Cancer MetastasisRev,2003,22(4):451-464. |
|
[10] Eyers FA, Maller JL. Kegulation of Xenopus Aurora A activationby TFX2[J].J Biol Chem,2004,279(10):9008-9015. |
|
[11] Ewart-Toland A, Briassouli P, de Koning JP, et al. Identification ofSTK6/STK15 as a candidate low-penetrance tumor-usceptibility gene Inmouse and human.Nat Genet, 2003, 3 (4):403-412. |
|
[12] Anand S, Fenrhyn,.owe S, Venkitaraman AR. ACRORA-Aamplification overrides the mitotic spindle assembly checkpoint,inducing resistance to Taxol[J].Cancer Cell,2003,3 (1):51-62. |
|
[13] Bischoff,JR, Plowman GD. The Aurora/IpIIp kinase family:regulators of chromosome segregation and cytokinesis[J].trendsCell Biol,1999,9(11):454-459. |
|
[14] Li D, Zhu J,Firozi PF, et al. Overexpression of oncogenic STK15/BTAK/ Aurora A kinase in human pancreatic cancer.ClinCancer Res,2003,9(3):991-997. |
|
[15] Jeng YM, Peng SY, Lin CY, et al. Overexpression andamplification of Aurora-A in hepatocellular carcinoma[J].ClinCancer Res,2004,10(6):2065-2071. |
|
[16] Sakakura C, Hagiwara A, Yasuoka R, et al. Tumour,mplifiedkinase BTAK is amplified and overexpressed in gastric cancerswith possible involvement in aneuploid formation[J].Br,JCancer,2001,84 (6):824-831. |
|
[17] Katayama H, Sasai K, Kawai H, et al. Phosphorylation by aurorakinase A induces Mdm2-medlated destabilization and inhibition ofNat Genet,2004,36(1):55-62 |
|
[18] Goepfert TM, Adigun YE Zhong L, et al. Centrosome amplificationand overexpression of aurora A are early events in rat mammarycarcinogenesis[J].Cancer Res,2002,62(14):4115-4122. |
|
[19] Yamamoto Y, Matsuyama H, Furuya T, et al. Centrosomehyperamplification predicts progression and tumor recurrence inbladder cancer[J].Clin Cancer Res, 2004, 10(19):6449-6455. |
|
[20] Mhawech-Fauceglia P, Fischer G, Beck A, et al.Rafl,Aurora-A/ STK15 and E-cadherin biomarkers expression in patients with pTa/pT1 urothelial bladder carcinoma; a retrospective TMA study of 246 patients with long-term follow-up[J].Eur J Surg Oncol, 2006,32(4):439-444. |
|
[21] Mhawech-Fauceglia P, Fischer G, Alvarez V,Jr, et al. Predicting outcome in minimally invasive (Tla and Tlb) urothelial bladder carcinoma using a panel of biomarkers: a high throughput tissue microarray analysis[J].BJC Int,2007,100(5):1182-1187. |
|
[23] Sen S, Zhou H, Zhang RD, et al. Amplification/overexpression of a mitotic kinase gene in human bladder cancer[J].,J Natl Cancer Inst,2002,94 (17):1320-1329. |
|
[24] Park HS, Park WS, Bondaruk,J, et al. Quantitation of Aurora kinase A gene copy number in urine sediments and bladder cancer detection[J].,J Natl Cancer Inst,2008，100 (19):1401-1411. |
|
[25] Comperat E Camparo P, Haus R, et al. Aurora-A/STK-15 is a predictive factor for recurrent behavior in non-invasive bladder carcinoma:a study of 128 cases of non-invasive neoplasms[J].Virchows Arch,2007,455 (4):419-424. |
|
[26] Mahadevan D, Bearss D,J, Vankayalapati H. Structure-based designof novel anticancer agents targeting aurora kinases[J].Curr MedChem Anticancer Agents,2003,3 (1):25-34. |
|
[27] Haul S, Cole RW, Laferra S, et al. The small moleculeHesperadin reveals a role for Aurora B in correcting kinetochore-Microtnbule attachment and in maintainint the spindle assemblyCheckpoint[J].J Cell Biol,2003,161 (2):281-294 |
|
[28] Harrington L,A, Bebbington D,Moore J，et al.VX-680, a potentand selective small melecule inhibiter of the Aurora kinases,suppresses tumor growth in vivo[J].Nature Med, 2004, 10 (3):262-267. |
|
[28] Fraizer GC, Diaz MF, Lee 1L, et al. Aurora-A/STK15/BTAK enhances chromosomal instability in bladder cancer cells[J].Int JOnco1,2004,25(6):1631-1639 |
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