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2004 Vol. 29, No. 5
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2004, 29(5): 377-379,390.
Abstract:
Objective: To study the relationship of paraneoplastic neurological syndromes(PNS) with malignant tumors and clinical types.Methods: Immunohistochemistry(ABC method) and Western blot analysis were used to detect specific neuronal antibodies in 430 PNS patients with malignant tumors.Results: Clinical types of 430 PNS patients include paraneoplastic sensory neuronopathy,paraneoplastic encephalomyelitis,paraneoplastic cerebellar degeneration,paraneoplastic limbic encephalitis and paraneoplastic opsoclonus myoclonus,PNS may complicate any malignant tumor but is more common with small cell lung cancer,breast cancer,ovarian cancer and Hodgkin's lymphoma.The high titer specific neuronal antibodies have been confirmed in the serum and cerebrospinal fluid of 281 patients.Conclusions: Various specific neuronal antibodies found in PNS patients strongly demonstrate that PNS is autoimmune disorders of nervous system resulting from malignant tumor,and detection of these specific neuronal antibodies is favorable for early diagnoses of PNS and associated malignant tumors.
Objective: To study the relationship of paraneoplastic neurological syndromes(PNS) with malignant tumors and clinical types.Methods: Immunohistochemistry(ABC method) and Western blot analysis were used to detect specific neuronal antibodies in 430 PNS patients with malignant tumors.Results: Clinical types of 430 PNS patients include paraneoplastic sensory neuronopathy,paraneoplastic encephalomyelitis,paraneoplastic cerebellar degeneration,paraneoplastic limbic encephalitis and paraneoplastic opsoclonus myoclonus,PNS may complicate any malignant tumor but is more common with small cell lung cancer,breast cancer,ovarian cancer and Hodgkin's lymphoma.The high titer specific neuronal antibodies have been confirmed in the serum and cerebrospinal fluid of 281 patients.Conclusions: Various specific neuronal antibodies found in PNS patients strongly demonstrate that PNS is autoimmune disorders of nervous system resulting from malignant tumor,and detection of these specific neuronal antibodies is favorable for early diagnoses of PNS and associated malignant tumors.
2004, 29(5): 380-382.
Abstract:
Objective: To investigate the safety and clinical effectiveness of microwave tissue coagulation(MTC) by fiberoptic bronchoscopy in treating central lung cancer.Methods: The canine respiratory was observed after microwave of various energy fire the wall of bronchus.The recovery of injury and pathological changes were observed under light microscope and electron microscope after canines were killed from 1 to 8 weeks.Lung cancer patients(n=90) with atelectasis and dyspnea were devided into two groups.One group was treated with MTC and chemotherapy(treatment group),the other group was treated only with chemotherapy(control group).The alleviating of symptom and change of X ray were observed.Activity of natural killer cell(NK cell) and lymphocyte blastagensis test(LBT) were detected.Results: All canine respiratory and the injury of bronchus were recovered quickly.Dyspnea of some cases was alleviated,activity of NK cell was elevated significantly(P<0.01) and atelectasis of patients were reinflated completely in 35 cases,reinflated partially in 8 cases in treatment group.Atelectasis of 8 cases were incompletely inflated in control group.Conclusions: MTC treatment in central lung cancer is safe and effective.MTC treatment can alleviate symptoms of airway obstruction and enhance immunity.
Objective: To investigate the safety and clinical effectiveness of microwave tissue coagulation(MTC) by fiberoptic bronchoscopy in treating central lung cancer.Methods: The canine respiratory was observed after microwave of various energy fire the wall of bronchus.The recovery of injury and pathological changes were observed under light microscope and electron microscope after canines were killed from 1 to 8 weeks.Lung cancer patients(n=90) with atelectasis and dyspnea were devided into two groups.One group was treated with MTC and chemotherapy(treatment group),the other group was treated only with chemotherapy(control group).The alleviating of symptom and change of X ray were observed.Activity of natural killer cell(NK cell) and lymphocyte blastagensis test(LBT) were detected.Results: All canine respiratory and the injury of bronchus were recovered quickly.Dyspnea of some cases was alleviated,activity of NK cell was elevated significantly(P<0.01) and atelectasis of patients were reinflated completely in 35 cases,reinflated partially in 8 cases in treatment group.Atelectasis of 8 cases were incompletely inflated in control group.Conclusions: MTC treatment in central lung cancer is safe and effective.MTC treatment can alleviate symptoms of airway obstruction and enhance immunity.
2004, 29(5): 383-384.
Abstract:
Objective: To study the relationship between microvessel density(MVD) of non-small cell lung cancer(NSCLC) tissues and the clinicopathological characteristics.Methods: The MVD was detected in 57 NSCLC tissues by immunohistochemical staining(S-P method) and the relationship of MVD to the clinical staging,pathologic typing and lymph node metastasis was studied.Results: MVD was closely related to the lymph node status,clinical staging and grade of cell differentiation of NSCLC(P<0.01),but not to the size of primary cancer,the histological classification and sex(P>0.05).Conclusions: MVD may play an important role in the oncogenesis,development and metastasis of NSCLC and is one of the reliable prognostic indicator of survials of NSCLC.
Objective: To study the relationship between microvessel density(MVD) of non-small cell lung cancer(NSCLC) tissues and the clinicopathological characteristics.Methods: The MVD was detected in 57 NSCLC tissues by immunohistochemical staining(S-P method) and the relationship of MVD to the clinical staging,pathologic typing and lymph node metastasis was studied.Results: MVD was closely related to the lymph node status,clinical staging and grade of cell differentiation of NSCLC(P<0.01),but not to the size of primary cancer,the histological classification and sex(P>0.05).Conclusions: MVD may play an important role in the oncogenesis,development and metastasis of NSCLC and is one of the reliable prognostic indicator of survials of NSCLC.
2004, 29(5): 385-387.
Abstract:
Objective: To investigate the protective effect of propofol on reperfusion arrhythmia and myocardial metabolism in isolated working rat heart.Methods: The healthy male SD rats were randomly divided into two experiment groups.The first experiment group was divided into 4 subgroups(with 10 animals in each subgroup):control group,propofol 10 μmol/L group(P10),50 μmol(P50) group and 100 μmol(P100) group;and the second experiment group(catecholamine depletion group) was divided into 3 subgroups(in with 10 anilmals in each subgroup):saline control group(SC),catecholamine-depleted group(DC) and catecholamine-depleted plus propofol 50 μmol group(DP).The isolated working heart model was used,and coronary outflow was collected for determination of creatine kinase(CK) and catecholamine(epinephrine,norepinephrine and dopamine) concentrations.Severity of arrhythmias was determinated with single ventricular premature beat(VPB),SALVO,ventricular tachycardia(VT) and ventricular fibrillation(VF).Results: Before ischemia,the frequency of the reperfusion arrhythmia was very low,the CK and catecholamine concentrations were not significantly different(P>0.05) among all the subgroups.During reperfusion,the frequency and severity of arrhythmias in subgroups P10,P50,P100,DC and DP were significantly less than that in the control groups(P<0.05);the epinephrine and norepinephrine concentrations in coronary outflow in subgroups P10,P50,P100 were significantly lower than that in control group,and the dopamine concentration were not significantly different in all subgroups;Catecholamine of group DC and DP was not detectable.The CK concentrations of the coronary outflow in subgroups P10,P50,P100 were significantly lower than that in control group.Conclusions: Propofol may markedly protect isolated heart from reperfusion arrhythmia through suppression of catecholamine release following ischemia-reperfusion.
Objective: To investigate the protective effect of propofol on reperfusion arrhythmia and myocardial metabolism in isolated working rat heart.Methods: The healthy male SD rats were randomly divided into two experiment groups.The first experiment group was divided into 4 subgroups(with 10 animals in each subgroup):control group,propofol 10 μmol/L group(P10),50 μmol(P50) group and 100 μmol(P100) group;and the second experiment group(catecholamine depletion group) was divided into 3 subgroups(in with 10 anilmals in each subgroup):saline control group(SC),catecholamine-depleted group(DC) and catecholamine-depleted plus propofol 50 μmol group(DP).The isolated working heart model was used,and coronary outflow was collected for determination of creatine kinase(CK) and catecholamine(epinephrine,norepinephrine and dopamine) concentrations.Severity of arrhythmias was determinated with single ventricular premature beat(VPB),SALVO,ventricular tachycardia(VT) and ventricular fibrillation(VF).Results: Before ischemia,the frequency of the reperfusion arrhythmia was very low,the CK and catecholamine concentrations were not significantly different(P>0.05) among all the subgroups.During reperfusion,the frequency and severity of arrhythmias in subgroups P10,P50,P100,DC and DP were significantly less than that in the control groups(P<0.05);the epinephrine and norepinephrine concentrations in coronary outflow in subgroups P10,P50,P100 were significantly lower than that in control group,and the dopamine concentration were not significantly different in all subgroups;Catecholamine of group DC and DP was not detectable.The CK concentrations of the coronary outflow in subgroups P10,P50,P100 were significantly lower than that in control group.Conclusions: Propofol may markedly protect isolated heart from reperfusion arrhythmia through suppression of catecholamine release following ischemia-reperfusion.
2004, 29(5): 388-390.
Abstract:
Objective: To establish the method for detection of phagocytosis of muirne neutrophils by flow cytometry.Methods: Staphylococcus aureus (S.aureus) and Escherichia coli (E.coli) were labeled with fluorescein isothiocyanate(FITC) in different buffers.The efficient rate of labeling was assessed by flow cytometry.Whole blood taken from mice were incubated with FITC labeled bacteria at 37℃ for 10-20 min,followed by lysing red blood cells.The fluorescent intensity of neutrophils was measured as phagocytotic rate by flow cytometry.Results: The good labeling of S.aureus and E.coli were obtained in PBS(pH 7.2) and carbonate buffer(pH 9),respectively.The percentage of phagocytosis of E.coli was higher than that of S.aureus by murine neutrophils.Conclusions: Detection of phagocytosis of FITC labeled E.coli by flow cytometry is simple,rapid and reproducible method for measuring phagocytotic activity of murine neutrophils.
Objective: To establish the method for detection of phagocytosis of muirne neutrophils by flow cytometry.Methods: Staphylococcus aureus (S.aureus) and Escherichia coli (E.coli) were labeled with fluorescein isothiocyanate(FITC) in different buffers.The efficient rate of labeling was assessed by flow cytometry.Whole blood taken from mice were incubated with FITC labeled bacteria at 37℃ for 10-20 min,followed by lysing red blood cells.The fluorescent intensity of neutrophils was measured as phagocytotic rate by flow cytometry.Results: The good labeling of S.aureus and E.coli were obtained in PBS(pH 7.2) and carbonate buffer(pH 9),respectively.The percentage of phagocytosis of E.coli was higher than that of S.aureus by murine neutrophils.Conclusions: Detection of phagocytosis of FITC labeled E.coli by flow cytometry is simple,rapid and reproducible method for measuring phagocytotic activity of murine neutrophils.
2004, 29(5): 391-392.
Abstract:
Objective: To study the efficacy of medroxyprogesterone in endometriosis after conservative surgery.Methods: From 1997 to 2000,102 women with endometriosis received conservative surgery in our hospital.They were divided into two groups.Group A(n=47) were treated with medroxyprogesterone(200 mg/d.Po) for six months.Group B(n=55) were for control.Relief and recurrent rates were analyzed six months and two years after surgery respectively.Results: The six-month symptom relief rates of the two groups were 100% and 81.8%,respectively(P<0.01).The sign relief rates of the two groups were 97.8% and 81.8%,respectively(P<0.01).The two year recurrent rates of the two groups were 8.5% and 23.6%,respectively(P<0.05).The level of alanine aminotransferase(ALT) increased in 2 of the 47 cases.Eleven of the 47 cases had nausea or vomiting.Conclusions: Using medroxyprogesterone after consevative surgery for endometriosis can reduce the recurrent rates.
Objective: To study the efficacy of medroxyprogesterone in endometriosis after conservative surgery.Methods: From 1997 to 2000,102 women with endometriosis received conservative surgery in our hospital.They were divided into two groups.Group A(n=47) were treated with medroxyprogesterone(200 mg/d.Po) for six months.Group B(n=55) were for control.Relief and recurrent rates were analyzed six months and two years after surgery respectively.Results: The six-month symptom relief rates of the two groups were 100% and 81.8%,respectively(P<0.01).The sign relief rates of the two groups were 97.8% and 81.8%,respectively(P<0.01).The two year recurrent rates of the two groups were 8.5% and 23.6%,respectively(P<0.05).The level of alanine aminotransferase(ALT) increased in 2 of the 47 cases.Eleven of the 47 cases had nausea or vomiting.Conclusions: Using medroxyprogesterone after consevative surgery for endometriosis can reduce the recurrent rates.
2004, 29(5): 393-395.
Abstract:
Objective: To study the heart rate variability(HRV) and blood pressure variability(BPV) in patients with different grades of hypertension.Methods: HRV and BPV were monitored and analyzed in 40 patients with normal blood pressure and 121 patients with hypertension.Results: HRV was significantly different between the two groups(P<0.05 to P<0.01)。The blood pressure increased and HRV tended to decrease.The BPV was significantly different(P<0.01) between the two groups;the blood pressure increased and the BPV tended to increase.Conclusions: The grade of hypertension is related to HRV and BPV.
Objective: To study the heart rate variability(HRV) and blood pressure variability(BPV) in patients with different grades of hypertension.Methods: HRV and BPV were monitored and analyzed in 40 patients with normal blood pressure and 121 patients with hypertension.Results: HRV was significantly different between the two groups(P<0.05 to P<0.01)。The blood pressure increased and HRV tended to decrease.The BPV was significantly different(P<0.01) between the two groups;the blood pressure increased and the BPV tended to increase.Conclusions: The grade of hypertension is related to HRV and BPV.
2004, 29(5): 395-397.
Abstract:
Objective: To explore the clinical characteristics of herpes simplex encephalitis(HSE) of children and to investigate the detective method and treatment.Methods: The clinical data of 22 cases of HSE,which were confirmed by detection of serum herpes simplex viruses(HSV) IgM antibody using enzyme immunodot technique were analyzed.All the patients were treated with ganciclovir(GCV).Results: HSE developed predominantly in children over 5 years of age.The most common clinical presentations of HSE were fever,vomiting,convulsion,paralysis,conscious disturbance and presentation of pyramidal sign.The lesions of frontal and temporal lobes of brain were common in the neuroimaging findings of the patients.Seven cases were cured,14 cases improved and 1 case did not respond.Conclusions: Clinical manifestations of HSE of children are not typical.The presence of serum specific HSV IgM antibody is a laboratory diagnostic evidence.HSE should be highly suspected if lesions of frontal and temporal lobes are present in the neuroimaging findings.GCV is the choice of therapy for HSE.
Objective: To explore the clinical characteristics of herpes simplex encephalitis(HSE) of children and to investigate the detective method and treatment.Methods: The clinical data of 22 cases of HSE,which were confirmed by detection of serum herpes simplex viruses(HSV) IgM antibody using enzyme immunodot technique were analyzed.All the patients were treated with ganciclovir(GCV).Results: HSE developed predominantly in children over 5 years of age.The most common clinical presentations of HSE were fever,vomiting,convulsion,paralysis,conscious disturbance and presentation of pyramidal sign.The lesions of frontal and temporal lobes of brain were common in the neuroimaging findings of the patients.Seven cases were cured,14 cases improved and 1 case did not respond.Conclusions: Clinical manifestations of HSE of children are not typical.The presence of serum specific HSV IgM antibody is a laboratory diagnostic evidence.HSE should be highly suspected if lesions of frontal and temporal lobes are present in the neuroimaging findings.GCV is the choice of therapy for HSE.
2004, 29(5): 398-399.
Abstract:
Objective: To investigate the effect of domperidone combined with doxepin on functional dyspepsia.Methods: One hundred and twenty patients with functional dyspepsia were randomly divided into 2 groups.Domperidone 10 mg was given 3 times per day and doxepin 50 mg per night to the therapeutic group,and domperidone 10 mg 3 times per day to the control group for 4 weeks.The symptom scores were measured before and 4 weeks after treatment.The effective index was calculated 4 weeks after the treatment.Results: The difference between the mean total symptom scores of the therapeutic group and control group before treatment was not significant(P>0.05).The total symptom scores of the two groups decreased significantly 4 weeks later,and the difference was significant in patients receiving domperidone combined with doxepin(P<0.01).The effective rate of medical group was significantly higher than that of the control group(P<0.01).Conclusions: Domperidone combined with doxepin is significantly effective in the treatment of functional dyspepsia.
Objective: To investigate the effect of domperidone combined with doxepin on functional dyspepsia.Methods: One hundred and twenty patients with functional dyspepsia were randomly divided into 2 groups.Domperidone 10 mg was given 3 times per day and doxepin 50 mg per night to the therapeutic group,and domperidone 10 mg 3 times per day to the control group for 4 weeks.The symptom scores were measured before and 4 weeks after treatment.The effective index was calculated 4 weeks after the treatment.Results: The difference between the mean total symptom scores of the therapeutic group and control group before treatment was not significant(P>0.05).The total symptom scores of the two groups decreased significantly 4 weeks later,and the difference was significant in patients receiving domperidone combined with doxepin(P<0.01).The effective rate of medical group was significantly higher than that of the control group(P<0.01).Conclusions: Domperidone combined with doxepin is significantly effective in the treatment of functional dyspepsia.
2004, 29(5): 400-402.
Abstract:
Objective: To assess the frequency of RBM gene microdeletion in men with idiopathic azoospermia and severe oligozoospermia,and to discuss the clinical significance of RBM gene detection.Methods: The RBM gene of peripheral blood leukocytes was detected by PCR technique in 22 azoospermia and 8 severe oligozoospermia patients.Results: RBM gene microdeletion was observed in 4 azoospermia and 2 severe oligozoospermia patients.Conclusions: As Azoospermic foctor deletion on Y chromosome long arm may be transmitted by vertical transmission,and result in infertile sons,detection of related genes is important for azoospermia and severe oligozoospermia patients before starting artificial insemination with the husband's semen and intracytoplasmic sperm injection in order to increase the eugenic birth rate.
Objective: To assess the frequency of RBM gene microdeletion in men with idiopathic azoospermia and severe oligozoospermia,and to discuss the clinical significance of RBM gene detection.Methods: The RBM gene of peripheral blood leukocytes was detected by PCR technique in 22 azoospermia and 8 severe oligozoospermia patients.Results: RBM gene microdeletion was observed in 4 azoospermia and 2 severe oligozoospermia patients.Conclusions: As Azoospermic foctor deletion on Y chromosome long arm may be transmitted by vertical transmission,and result in infertile sons,detection of related genes is important for azoospermia and severe oligozoospermia patients before starting artificial insemination with the husband's semen and intracytoplasmic sperm injection in order to increase the eugenic birth rate.
2004, 29(5): 402-404.
Abstract:
Objective: To observe the influence of epidural anesthesia on heart rate variability(HRV).Methods: Twenty-five ASA ⅠtoⅡ patients scheduled for elective surgery under epidural anesthesia were included in this study.They were divided into two groups according to the segment of epidural block.Group A included 15 patients undergoing cholecystectomy or gastrectomy under epidural anesthesia on middle chest segment and group B included 10 patients undergoing orthopaedics operation on lower limbs under epidural anesthesia on lumbar segment.The Power spectrum of HRV,heart rate and blood pressure(BP) were observed before and after epidural anesthesia.Results: The value of low frequency(LF) and BP were markedly reduced 5,10,15 and 20 minutes after epidural anesthesia on middle chest segment(P<0.05).The value of LF correlated closely with BP(r=0.980 2, P<0.01).HRV changed little after epidural anesthesia on lumbar segment.Conclusions: The epidural anesthesia on middle chest segment has influence on HRV and reduces the value of LF reflecting the tension of the sympathetic nerve,which correlates with the level of epidural block.
Objective: To observe the influence of epidural anesthesia on heart rate variability(HRV).Methods: Twenty-five ASA ⅠtoⅡ patients scheduled for elective surgery under epidural anesthesia were included in this study.They were divided into two groups according to the segment of epidural block.Group A included 15 patients undergoing cholecystectomy or gastrectomy under epidural anesthesia on middle chest segment and group B included 10 patients undergoing orthopaedics operation on lower limbs under epidural anesthesia on lumbar segment.The Power spectrum of HRV,heart rate and blood pressure(BP) were observed before and after epidural anesthesia.Results: The value of low frequency(LF) and BP were markedly reduced 5,10,15 and 20 minutes after epidural anesthesia on middle chest segment(P<0.05).The value of LF correlated closely with BP(r=0.980 2, P<0.01).HRV changed little after epidural anesthesia on lumbar segment.Conclusions: The epidural anesthesia on middle chest segment has influence on HRV and reduces the value of LF reflecting the tension of the sympathetic nerve,which correlates with the level of epidural block.
2004, 29(5): 405-406.
Abstract:
Objective: To investigate the effects of granisetron on complications induced by transcatheter arterial chemoembolization(TACE).Methods: Forty-four patients with hepatocellular carcinoma after TACE were divided into 2 groups.The first group used granisetron during the surgery.The second group used granisetron within 24 hours after the surgery.Results: The complications induced by TACE,such as nausea and vomiting,decreased significantly in the first group compared with those in the other group.Conclusions: The effects of granisetron on complications induced by TACE are obvious.Use of granisetron is important for the prognosis of patients with hepatocellular carcinoma after TACE.
Objective: To investigate the effects of granisetron on complications induced by transcatheter arterial chemoembolization(TACE).Methods: Forty-four patients with hepatocellular carcinoma after TACE were divided into 2 groups.The first group used granisetron during the surgery.The second group used granisetron within 24 hours after the surgery.Results: The complications induced by TACE,such as nausea and vomiting,decreased significantly in the first group compared with those in the other group.Conclusions: The effects of granisetron on complications induced by TACE are obvious.Use of granisetron is important for the prognosis of patients with hepatocellular carcinoma after TACE.
2004, 29(5): 407-409.
Abstract:
Objective: To explore the clinical features and methods for treatment of acute cholangitis of severe type(ACST) in the aged.Methods: Forty-six aged patients with ACST treated in our hospital from 1994 to 2003 were analyzed retrospectively.Results: Twelve patients died,with a mortality of 26.1%,7 of whom died of toxic shock(58.3%) and 5 died of multiple organ failure(41.7%).Conclusions: The ACST in the aged patients has the characteristics of lack of typical clinical manifestations,more coexisting diseases, toxic shock,electrolyte disturbance and multiple organ failure.Good pre-operative preparations,choice of operation time and procedure,good postoperative management are the key to the success of the operation.
Objective: To explore the clinical features and methods for treatment of acute cholangitis of severe type(ACST) in the aged.Methods: Forty-six aged patients with ACST treated in our hospital from 1994 to 2003 were analyzed retrospectively.Results: Twelve patients died,with a mortality of 26.1%,7 of whom died of toxic shock(58.3%) and 5 died of multiple organ failure(41.7%).Conclusions: The ACST in the aged patients has the characteristics of lack of typical clinical manifestations,more coexisting diseases, toxic shock,electrolyte disturbance and multiple organ failure.Good pre-operative preparations,choice of operation time and procedure,good postoperative management are the key to the success of the operation.
2004, 29(5): 409-410.
Abstract:
Objective: To discuss the indications and technical skills for laparoscopic cholecystectomy(LC) liver cirrhosis patients.Methods: Forty-three liver cirrhosis patients(35 Child A and 8 Child B),who had calculous cholecystitis and had received LC,were analyzed retrospectively.Results: All the patients recoverd well with no biliary duct trauma,introperitoneal infection or postoperative bleeding.Conclusions: On condition of proper surgical indication meticulous preoperative preparation and skilled technique,satisfactory results can be achieved in cirrhosis patients with LC.
Objective: To discuss the indications and technical skills for laparoscopic cholecystectomy(LC) liver cirrhosis patients.Methods: Forty-three liver cirrhosis patients(35 Child A and 8 Child B),who had calculous cholecystitis and had received LC,were analyzed retrospectively.Results: All the patients recoverd well with no biliary duct trauma,introperitoneal infection or postoperative bleeding.Conclusions: On condition of proper surgical indication meticulous preoperative preparation and skilled technique,satisfactory results can be achieved in cirrhosis patients with LC.
2004, 29(5): 411-412.
Abstract:
Objective: To summarize the experience of surgical treatment for patients with deep vein thrombosis(DVT) of the lower extremity.Methods: Thirty-two patients with DVT were diagnosed by ascending lower extremity deep vine angiography or color Doppler ultrasonic examination.All the patients were performed embolectomy with Fogarty.Twenty-nine cases underwent reconstruction,of whom,3 were performed Palma-Dell operation and 26 communis iliac vein femord vein transplantion trans current.The anticoagulant and thrombolytic therapy was used during and after the operation.Results: The swelling in 17 cases(18 lower limbs) faded away completely after operation and the swelling in 9 cases faded away after exerxises.Three cases recurred.The success rate was 16/26(64%) in the acute patients and 4/11(36.3%) in the chronic patients.One patient died of pulmonary embolism.Conclusions: DVT combined with reconstruction was effective for treatment of patient with acute deep vein thrombosis of the lower extremity.Measures should be taken to prevent recurrence after operation.
Objective: To summarize the experience of surgical treatment for patients with deep vein thrombosis(DVT) of the lower extremity.Methods: Thirty-two patients with DVT were diagnosed by ascending lower extremity deep vine angiography or color Doppler ultrasonic examination.All the patients were performed embolectomy with Fogarty.Twenty-nine cases underwent reconstruction,of whom,3 were performed Palma-Dell operation and 26 communis iliac vein femord vein transplantion trans current.The anticoagulant and thrombolytic therapy was used during and after the operation.Results: The swelling in 17 cases(18 lower limbs) faded away completely after operation and the swelling in 9 cases faded away after exerxises.Three cases recurred.The success rate was 16/26(64%) in the acute patients and 4/11(36.3%) in the chronic patients.One patient died of pulmonary embolism.Conclusions: DVT combined with reconstruction was effective for treatment of patient with acute deep vein thrombosis of the lower extremity.Measures should be taken to prevent recurrence after operation.
2004, 29(5): 413-414.
Abstract:
Objective: To evaluate the remittent function and safety of ballon dilation in treatment of patients with cardial benign stenosis of esophagus accompanied with dysphagia and to observe the near-term effect.Methods: The ballon was put into the narrow part of the esophagus of 17 patients through their mouths using a saccular catheter.Twenty percent of meglumine adipiodone was injected into the ballon to expand the ballon to a diameter of 2.5-3.5 cm.Results: The effective rate was 94.12%(16/17) one week after the ballon dilation and 82.35%(14/17) three months later.Esophageal perforation occurred in one case(1/7).Conclusions: Ballon dilation is safe and effective for treatment of cardial benign stenosis of esophagus.
Objective: To evaluate the remittent function and safety of ballon dilation in treatment of patients with cardial benign stenosis of esophagus accompanied with dysphagia and to observe the near-term effect.Methods: The ballon was put into the narrow part of the esophagus of 17 patients through their mouths using a saccular catheter.Twenty percent of meglumine adipiodone was injected into the ballon to expand the ballon to a diameter of 2.5-3.5 cm.Results: The effective rate was 94.12%(16/17) one week after the ballon dilation and 82.35%(14/17) three months later.Esophageal perforation occurred in one case(1/7).Conclusions: Ballon dilation is safe and effective for treatment of cardial benign stenosis of esophagus.
2004, 29(5): 415-416.
Abstract:
Objective: To study the curative effect of distal clavicular fracture and acromioclavicular joint dislocation with clavicular hook plate.Methods: Thirteen cases of distal clavicular fracture and 9 cases of acromioclavicular joint dislocation were treated with the clavicular hook plate.Results: Twenty-two cases were followed up for 4 to 20 months,with an average of 10 months.All the fractures were healed and no redislocation was observed.The effects were excellent in 18 cases and good in 4 cases according to the Lazzcano standard.Conclusions: Treatment of distal clavicular fracture and acromiaclavicular joint dislocation with clavicular hook plate has the advantages of rigid fixation and no invasion of article surface,which will enable the patients to start functional exercises earlier and recovered more quickly.It is an ideal surgical method.
Objective: To study the curative effect of distal clavicular fracture and acromioclavicular joint dislocation with clavicular hook plate.Methods: Thirteen cases of distal clavicular fracture and 9 cases of acromioclavicular joint dislocation were treated with the clavicular hook plate.Results: Twenty-two cases were followed up for 4 to 20 months,with an average of 10 months.All the fractures were healed and no redislocation was observed.The effects were excellent in 18 cases and good in 4 cases according to the Lazzcano standard.Conclusions: Treatment of distal clavicular fracture and acromiaclavicular joint dislocation with clavicular hook plate has the advantages of rigid fixation and no invasion of article surface,which will enable the patients to start functional exercises earlier and recovered more quickly.It is an ideal surgical method.
2004, 29(5): 417-418.
Abstract:
Objective: To probe into the gastroscopic and clinical characteristics of the peptic ulcer in the students of the middle and primary school.Methods: Thirty-five cases of the peptic ulcer in the students of the middle and primary school confirmed by gastroscope in past 8 years were analyzed retrospectively.Results: Among the 35 patients,27 were middle school students and 8 were primary school students.The ratio of middle school students and primary school students was 3.4:1;and the ratio of male and femal was 2.9:1;26 were of duodenal ulcer(74.3%),7 gastric ulcer(20.0%) and 2 compounding ulcer(5.7%); Helicobateria pylori infection rate was 54.3%.Conclusions: As the clinical symptoms of peptic ulcer in students of middle and primary schools are not typical,it is liable to misdiagnosis,or leak diagnosis,delaying the treatment in time.Gastroscopy is an easy,safe and reliable method for the diagnosis of the disease.
Objective: To probe into the gastroscopic and clinical characteristics of the peptic ulcer in the students of the middle and primary school.Methods: Thirty-five cases of the peptic ulcer in the students of the middle and primary school confirmed by gastroscope in past 8 years were analyzed retrospectively.Results: Among the 35 patients,27 were middle school students and 8 were primary school students.The ratio of middle school students and primary school students was 3.4:1;and the ratio of male and femal was 2.9:1;26 were of duodenal ulcer(74.3%),7 gastric ulcer(20.0%) and 2 compounding ulcer(5.7%); Helicobateria pylori infection rate was 54.3%.Conclusions: As the clinical symptoms of peptic ulcer in students of middle and primary schools are not typical,it is liable to misdiagnosis,or leak diagnosis,delaying the treatment in time.Gastroscopy is an easy,safe and reliable method for the diagnosis of the disease.
2004, 29(5): 419-420.
Abstract:
Objective: To analyze the import of rotavirus infection in infantile diarrhea.Methods: Stool specimens from 1 323 infants with diarrhea from 2001 to 2003 were detected by ELISA.Results: Rotavirus was detected from 600 of 1 323 stool specimens.The positive rate was 45.4% in the years.The peak season of rotavirus infection was from October to December.The positive rates of the age groups of ≤ 6 months,>6 months to 2 years,>2 to 5 years were 18.8%,53.4% and 13.8% respectively in 2003.The positive rate of the males was higher than that of the females(P<0.05).Conclusions: Rotavirus was the main pathogen in infantile diarrhea of the age group of 6 months to 2 years.
Objective: To analyze the import of rotavirus infection in infantile diarrhea.Methods: Stool specimens from 1 323 infants with diarrhea from 2001 to 2003 were detected by ELISA.Results: Rotavirus was detected from 600 of 1 323 stool specimens.The positive rate was 45.4% in the years.The peak season of rotavirus infection was from October to December.The positive rates of the age groups of ≤ 6 months,>6 months to 2 years,>2 to 5 years were 18.8%,53.4% and 13.8% respectively in 2003.The positive rate of the males was higher than that of the females(P<0.05).Conclusions: Rotavirus was the main pathogen in infantile diarrhea of the age group of 6 months to 2 years.
2004, 29(5): 421-422.
Abstract:
Objective: To explore the effect of golden bifid combined with smecta on infantile diarrhea.Methods: One hundred and five infants suffering from diarrhea were randomly divided into two groups.The therapy group was treated with oral golden bifid and smecta and the control group with gentamycin.The effects were analyzed.Results: The total response rate of the therapy group was 94.0%,with was significantly higher than that of the control group(65.5%)(P<0.005).Conclusions: It is safe and effective to treat infantsile diarrhea by combined therapy of golden bifid and smecta.
Objective: To explore the effect of golden bifid combined with smecta on infantile diarrhea.Methods: One hundred and five infants suffering from diarrhea were randomly divided into two groups.The therapy group was treated with oral golden bifid and smecta and the control group with gentamycin.The effects were analyzed.Results: The total response rate of the therapy group was 94.0%,with was significantly higher than that of the control group(65.5%)(P<0.005).Conclusions: It is safe and effective to treat infantsile diarrhea by combined therapy of golden bifid and smecta.
2004, 29(5): 423-424.
Abstract:
Objective: To sum up the experience in the diagnosis and treatment of huge cerycical leiomyoma.Methods: Twelve cases of the huge cervical leiomyoma treated in our hospital were reviewed retrospectively.Results: The misdiagnostic rate of the huge cervical leiomyoma was 75%.One case of ureter was damaged during the operation.Conclusions: The diagnosis of the huge cervical leiomyoma is difficult.Correct diagnosis can be made by means of medical history,gynecological examination and B ultrasonography.
Objective: To sum up the experience in the diagnosis and treatment of huge cerycical leiomyoma.Methods: Twelve cases of the huge cervical leiomyoma treated in our hospital were reviewed retrospectively.Results: The misdiagnostic rate of the huge cervical leiomyoma was 75%.One case of ureter was damaged during the operation.Conclusions: The diagnosis of the huge cervical leiomyoma is difficult.Correct diagnosis can be made by means of medical history,gynecological examination and B ultrasonography.
2004, 29(5): 424-425.
Abstract:
Objective: To analyze the therapeutic effect of primary incision plus radical operation on perianal abscess.Methods: Of all the cases 42 cases received primary radical incision,5 cases primary radical incision and thread drawing.Results: The postoperative cure rate by primary radical incision was 91.4%(43/47).No relapse was found during the 0.5 to 3.0 years.Conclusions: The key points of operational success were correct localization of the internal orifice,rational selection of surgical operation and prevention of fecal incontinence.
Objective: To analyze the therapeutic effect of primary incision plus radical operation on perianal abscess.Methods: Of all the cases 42 cases received primary radical incision,5 cases primary radical incision and thread drawing.Results: The postoperative cure rate by primary radical incision was 91.4%(43/47).No relapse was found during the 0.5 to 3.0 years.Conclusions: The key points of operational success were correct localization of the internal orifice,rational selection of surgical operation and prevention of fecal incontinence.
2004, 29(5): 426-427.
Abstract:
Objective: To improve the surgical result in treatment of subdural effusion in children.Methods: The clinical data of 42 patients with subdural effusion from Jan.1990 to Jan.2004 were analyzed retrospectively,36 of whom received surgical treatment.Repeated tapping was performed in 16 cases,persistent drainage in 12 cases,drainage followed by craniotomy in 4 cases and drainage followed by shunt in 4 cases.Results: Among the 36 cases,25 cases were cured,7 cases were improved and 4 cases failed to respond.Conclusions: The choice of treatment depends on the difference of subdural effusion in children.
Objective: To improve the surgical result in treatment of subdural effusion in children.Methods: The clinical data of 42 patients with subdural effusion from Jan.1990 to Jan.2004 were analyzed retrospectively,36 of whom received surgical treatment.Repeated tapping was performed in 16 cases,persistent drainage in 12 cases,drainage followed by craniotomy in 4 cases and drainage followed by shunt in 4 cases.Results: Among the 36 cases,25 cases were cured,7 cases were improved and 4 cases failed to respond.Conclusions: The choice of treatment depends on the difference of subdural effusion in children.
2004, 29(5): 428-430.
Abstract:
Objective: To study the clinical effect of ferrous gluconate on children with recurrent respiratory tract infections(RRTI).Methods: One hundred and eight children with RRTI and iron deficiency anemia(IDA) were divided into two groups.The observation group were given ferrous gluconate on the basis of routine therapy and the control group were treated by routine therapy.Serum specimens were collected before and after the treatment.IgG,IgA,IgM were determined by scattered nephelometry and the curative effect was evaluated.Results: The levels of serum IgG,IgA in the observation group were higher than that of the controls(P<0.001).The response rate in the observation group was higher than that in the control group(71.19% vs 32.35%)(P<0.005).Conclusions: Iron deficiency is highly related to the development of RRTI in children.To determine the iron concentration and to replenish iron preparation is beneifcial to the treatment of children with RRTI.
Objective: To study the clinical effect of ferrous gluconate on children with recurrent respiratory tract infections(RRTI).Methods: One hundred and eight children with RRTI and iron deficiency anemia(IDA) were divided into two groups.The observation group were given ferrous gluconate on the basis of routine therapy and the control group were treated by routine therapy.Serum specimens were collected before and after the treatment.IgG,IgA,IgM were determined by scattered nephelometry and the curative effect was evaluated.Results: The levels of serum IgG,IgA in the observation group were higher than that of the controls(P<0.001).The response rate in the observation group was higher than that in the control group(71.19% vs 32.35%)(P<0.005).Conclusions: Iron deficiency is highly related to the development of RRTI in children.To determine the iron concentration and to replenish iron preparation is beneifcial to the treatment of children with RRTI.
2004, 29(5): 430-432.
Abstract:
Objective: To sum up the experience in treating femoral shaft fracture with interlocking intramedullary nail.Methods: Sixty-two cases of femoral shaft fractures were treated with close reduction or limited open reduction,reamed marrow cavity and static fixation and target devices were used to lock the fracture.Results: All the cases were followed up for 6 to 8 months.All the fractures were healed.The effect was excellent in 39 cases,good in 17 cases and poor in 4 cases according to the criteria of Ma Yuanzhang.Conclusions: Interlocking intramedullary nail is the choice of treatment for femoral shaft fracture.It has the advantages of firm fixation,good healing,good articular function,few complications and manipulation easy.It is worth popularizing.
Objective: To sum up the experience in treating femoral shaft fracture with interlocking intramedullary nail.Methods: Sixty-two cases of femoral shaft fractures were treated with close reduction or limited open reduction,reamed marrow cavity and static fixation and target devices were used to lock the fracture.Results: All the cases were followed up for 6 to 8 months.All the fractures were healed.The effect was excellent in 39 cases,good in 17 cases and poor in 4 cases according to the criteria of Ma Yuanzhang.Conclusions: Interlocking intramedullary nail is the choice of treatment for femoral shaft fracture.It has the advantages of firm fixation,good healing,good articular function,few complications and manipulation easy.It is worth popularizing.
2004, 29(5): 433-435.
Abstract:
Objective: To investigate the clinical features of cytomegalovirus(CMV) pneumonia and the therapeutic effect of ganciclovir(GCV)in treatment of the disease.Methods: The clinical features of 46 children with CMV pneumonia were analyzed retrospectively.The clinical symptom,sign,ALT,chest radiographs,and the size of liver and spleen were detected before and after GCV therapy.Results: Cough was the most common symptom of CMV pneumonia in infants(82.61%).CMV pneumonia cases showed interstitial pneumonia(80.43%).Children with CMV pneumonia more often had liver and spleen involvement.After 14 days of GVC(from 5 to 7.5 mg/kg Q12h intravenous infusion) therapy,the clinical symptom,sign,chest radiographs,enlarged liver and spleen,and liver function improved.No obvious adverse effect was observed during the therapy.Conclusions: CMV pneumonia should be considered in infants with cough and complications.GCV is safe and effective in treatment of CMV infection.
Objective: To investigate the clinical features of cytomegalovirus(CMV) pneumonia and the therapeutic effect of ganciclovir(GCV)in treatment of the disease.Methods: The clinical features of 46 children with CMV pneumonia were analyzed retrospectively.The clinical symptom,sign,ALT,chest radiographs,and the size of liver and spleen were detected before and after GCV therapy.Results: Cough was the most common symptom of CMV pneumonia in infants(82.61%).CMV pneumonia cases showed interstitial pneumonia(80.43%).Children with CMV pneumonia more often had liver and spleen involvement.After 14 days of GVC(from 5 to 7.5 mg/kg Q12h intravenous infusion) therapy,the clinical symptom,sign,chest radiographs,enlarged liver and spleen,and liver function improved.No obvious adverse effect was observed during the therapy.Conclusions: CMV pneumonia should be considered in infants with cough and complications.GCV is safe and effective in treatment of CMV infection.
2004, 29(5): 435-436.
Abstract:
Objective: To investigate the diagnosis and removal of tracheobronchial foreign bodies in children.Methods: The diagnosis and removal of tracheobronchial foreign bodies in 45 children were reviewed and analysed.Results: Some foreign bodies such as pen-caps,plastic whistles,melon seeds and others were successfully removed in 41 cases;pre-operative expectoration occurred in 4 cases.Conclusions: Early diagnosis and removal of the foreign bodies,fully pre-operative preparation,and suitable ways of operation are the key to success.
Objective: To investigate the diagnosis and removal of tracheobronchial foreign bodies in children.Methods: The diagnosis and removal of tracheobronchial foreign bodies in 45 children were reviewed and analysed.Results: Some foreign bodies such as pen-caps,plastic whistles,melon seeds and others were successfully removed in 41 cases;pre-operative expectoration occurred in 4 cases.Conclusions: Early diagnosis and removal of the foreign bodies,fully pre-operative preparation,and suitable ways of operation are the key to success.
2004, 29(5): 465-467.
Abstract:
Objective: To evaluate the effects of jaundice discoloration and lipemia of various concentrations on enzymatic method for determining serum potassium.Methods: Serum potassium concentrations of the lipemic or jaundice samples were assayed based on electryte dependent pyruvate kinase and the results were compared with those obtained by direct ion-selective electrodes(ISE).Results: When serum triglyceride concentration below 10.0 mmo1/L,the potassium results obtained by the two methods were not significant different and in good agreement(r=0.926 6),but when serum triglyceride concentrations above 10 mmol/L,the potassium results get by enzymatic method significantly lowed than those by ISE method,and for some grossly lipemic samples(23/43),enzymatic method get no potassium results.And jaundice discoloration had no effect on enzymatic determination serum potassium concentration,and the two methods had a good correlation(r=0.990 3).Conclusions: Middle(<10.0 mmol/L) not grossly(>.0 mmol/L) lipemia or icterus have no effects on enzymatic method for determination of serum potassium,and the enzymatic method offers a practical alternative to the use of ISE or flame photometry for measuring serum potassium on one clinical chemistry analyzer by spectrophotometry.
Objective: To evaluate the effects of jaundice discoloration and lipemia of various concentrations on enzymatic method for determining serum potassium.Methods: Serum potassium concentrations of the lipemic or jaundice samples were assayed based on electryte dependent pyruvate kinase and the results were compared with those obtained by direct ion-selective electrodes(ISE).Results: When serum triglyceride concentration below 10.0 mmo1/L,the potassium results obtained by the two methods were not significant different and in good agreement(r=0.926 6),but when serum triglyceride concentrations above 10 mmol/L,the potassium results get by enzymatic method significantly lowed than those by ISE method,and for some grossly lipemic samples(23/43),enzymatic method get no potassium results.And jaundice discoloration had no effect on enzymatic determination serum potassium concentration,and the two methods had a good correlation(r=0.990 3).Conclusions: Middle(<10.0 mmol/L) not grossly(>.0 mmol/L) lipemia or icterus have no effects on enzymatic method for determination of serum potassium,and the enzymatic method offers a practical alternative to the use of ISE or flame photometry for measuring serum potassium on one clinical chemistry analyzer by spectrophotometry.
2004, 29(5): 467-468.
Abstract:
Objective: To investigate the in vitro dissolution results of enteric-coaled tablets of indometacin probided by 6 different drug manufacturers.Methods: The dissolution tests were carried out with the rotating basket.The ultraviolet spectrometric assay was used to determine the concentration of indometacin in dissolution media.The cumulative dissolution percent of the labeled amount was calculated and the Weibull's equation was used to model the main dissolution parameters according to the dissolution data.The differences between different groups were statistically analysed.Results: The dissolution data of the indometacin tablets produced by different manufacturers meet the requirements of pharmacopoeia in the dissolution test with acidic medium(0.1 mol/L HCL),but one kind of indometacin tablet failed to meet the requirements of pharmacopoeia in the dissolution test with pH 6.8 phosphate buffer solution.Conclusions: The dissolution parameters of the enteric-coated tablets of indometacin from 6 different manifactures differ greatly.
Objective: To investigate the in vitro dissolution results of enteric-coaled tablets of indometacin probided by 6 different drug manufacturers.Methods: The dissolution tests were carried out with the rotating basket.The ultraviolet spectrometric assay was used to determine the concentration of indometacin in dissolution media.The cumulative dissolution percent of the labeled amount was calculated and the Weibull's equation was used to model the main dissolution parameters according to the dissolution data.The differences between different groups were statistically analysed.Results: The dissolution data of the indometacin tablets produced by different manufacturers meet the requirements of pharmacopoeia in the dissolution test with acidic medium(0.1 mol/L HCL),but one kind of indometacin tablet failed to meet the requirements of pharmacopoeia in the dissolution test with pH 6.8 phosphate buffer solution.Conclusions: The dissolution parameters of the enteric-coated tablets of indometacin from 6 different manifactures differ greatly.
2004, 29(5): 469-471.
Abstract:
Objective: To study the infection of HBV and the different patterns of six serological markers in population.Methods: HBsAg,anti-HBs,HBeAg,anti-HBe,anti-HBc IgG and anti-HBc IgM in the serum samples from 1 562 non-hepatictis patients detected by ELISA.Results: The results were negative in 837 cases,accounting for 53.6% of the total cases and the results were positive,in 725 cases,accounting for 46.4% of the total cases.There were 18 different patterns in all,which could be divided into two groups:infection pattern group and recovery pattern group.The pattern "145" and "135" were predomintant in the infection pattern group and the pattern "2" was prodomintant in the recovery pattern group.Conclusions: Although people have realized the importance of HBV immunization,the rate of HBV infection is still high in population.Having understood these patterns of serological markers of HBV,we can test the infection status of HBV more accurate by ELISA.
Objective: To study the infection of HBV and the different patterns of six serological markers in population.Methods: HBsAg,anti-HBs,HBeAg,anti-HBe,anti-HBc IgG and anti-HBc IgM in the serum samples from 1 562 non-hepatictis patients detected by ELISA.Results: The results were negative in 837 cases,accounting for 53.6% of the total cases and the results were positive,in 725 cases,accounting for 46.4% of the total cases.There were 18 different patterns in all,which could be divided into two groups:infection pattern group and recovery pattern group.The pattern "145" and "135" were predomintant in the infection pattern group and the pattern "2" was prodomintant in the recovery pattern group.Conclusions: Although people have realized the importance of HBV immunization,the rate of HBV infection is still high in population.Having understood these patterns of serological markers of HBV,we can test the infection status of HBV more accurate by ELISA.
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