Author Login
Experts Review
Academic Editor
Editor-in-chief
2012 Vol. 37, No. 2
Display Method:
2012, 36(2): 131-133.
Abstract:
Objective:To explore the changes of CD14 expression before and after THP-1 cells infected with Mycobacterium tuberculosis(Mtb). Methods:Mtb and phorbol myristate acetate(PMA)-differentiated THP-1 cells were incubated with the ratio of 10∶1,and Mtb infection cell model was established.The CD14 expression in THP-1 cells,PMA differentiated THP-1 cells and Mtb infected THP-1 cells were detected by flow cytometry. Results:The percentage of CD14 expression in THP-1 cells and PMA differentiated THP-1 cells was 5.5%,and 21.6%,respectively,whereas the percentage of Mtb phagocytosis rate was 7.7% and 93.0%,respectively.The percentage of CD14 expression in Mtb infected THP-1 cells was 27.5%. Conclusions:The CD14 expression in PMA differentiated THP-1 cells is increased,and the CD14 expression and Mtb phagocytosis rate in Mtb infected THP-1 cells are further increased.
Objective:To explore the changes of CD14 expression before and after THP-1 cells infected with Mycobacterium tuberculosis(Mtb). Methods:Mtb and phorbol myristate acetate(PMA)-differentiated THP-1 cells were incubated with the ratio of 10∶1,and Mtb infection cell model was established.The CD14 expression in THP-1 cells,PMA differentiated THP-1 cells and Mtb infected THP-1 cells were detected by flow cytometry. Results:The percentage of CD14 expression in THP-1 cells and PMA differentiated THP-1 cells was 5.5%,and 21.6%,respectively,whereas the percentage of Mtb phagocytosis rate was 7.7% and 93.0%,respectively.The percentage of CD14 expression in Mtb infected THP-1 cells was 27.5%. Conclusions:The CD14 expression in PMA differentiated THP-1 cells is increased,and the CD14 expression and Mtb phagocytosis rate in Mtb infected THP-1 cells are further increased.
2012, 36(2): 134-137.
Abstract:
Objective:To investigate the effect of panax notoginseng saponins R1 on gap junction(GJ) function in HeLa cells transfected with connexin 32 and connexin 26 plasmid and the cytotoxity of cisplatin. Methods:Sulforhodamine B assay was used to determine the inhibitory effect of panax notoginseng saponin R1 on HeLa cells growth for different times.Cells were divided into panax notoginseng saponins R1 10,25,50,100,and 200 mol/L groups,and non-R1 group was taken as the blank control group.After 24,48,and 72 hours the inhibition rate of HeLa cells growth was evaluated;the GJ function of HeLa cells treated with R1 for 48 hours was detected by SL/DT(scrape-loading dye transfer),and distance between cells of lucifer yellow was introduced to reflect the GJ function.The cytotoxity of cisplatin combined with R1 was determined by Standard colony-forming assay,and Surviving Fraction as index was used to evaluate the cytotoxicity of cisplatin. Results:Panax notoginseng saponins R1 suppressed the growth of HeLa cells;R1 up-regulated the GJ of HeLa cells.In the presence of GJ,combination of R1 and cisplatin significantly enhance the cytotoxicity of cisplatin compared with cisplatin treatment group,but in absence of GJ,there was no significant difference between these two groups. Conclusions:R1 enhances the cytotoxicity of cisplatin through enhancement of GJ function.
Objective:To investigate the effect of panax notoginseng saponins R1 on gap junction(GJ) function in HeLa cells transfected with connexin 32 and connexin 26 plasmid and the cytotoxity of cisplatin. Methods:Sulforhodamine B assay was used to determine the inhibitory effect of panax notoginseng saponin R1 on HeLa cells growth for different times.Cells were divided into panax notoginseng saponins R1 10,25,50,100,and 200 mol/L groups,and non-R1 group was taken as the blank control group.After 24,48,and 72 hours the inhibition rate of HeLa cells growth was evaluated;the GJ function of HeLa cells treated with R1 for 48 hours was detected by SL/DT(scrape-loading dye transfer),and distance between cells of lucifer yellow was introduced to reflect the GJ function.The cytotoxity of cisplatin combined with R1 was determined by Standard colony-forming assay,and Surviving Fraction as index was used to evaluate the cytotoxicity of cisplatin. Results:Panax notoginseng saponins R1 suppressed the growth of HeLa cells;R1 up-regulated the GJ of HeLa cells.In the presence of GJ,combination of R1 and cisplatin significantly enhance the cytotoxicity of cisplatin compared with cisplatin treatment group,but in absence of GJ,there was no significant difference between these two groups. Conclusions:R1 enhances the cytotoxicity of cisplatin through enhancement of GJ function.
2012, 36(2): 137-141.
Abstract:
Objective:To explore the mechanism of protective effect of erythropoietin on the doxorubicin induced diaphragm injury in rats. Methods:Thirty rats were divided into three groups: normal control group(n=10),model group(n=10) and erythropoietin group(n=10).Diaphragm strips was isolated to observe peak twitch tension(Pt),maximum titanic tension(Po),time to peak contraction(CT),half relaxation time(1/2RT),maximal rates of contraction(+dT/dtmax),maximal rates of relaxation(-dT/dtmax) and force-frequency curve.Meanwhile,the activity of superoxide dismutase(SOD) and content of malondialdehyde(MDA) in diaphragm were also measured.Electron microscope was used to observe the changes of diaphragm cell ultrastructure. Results:Pt,Po,+dT/dtmax,-dT/dtmax in model group were lower than those in control group(P0.01),the above four indexes in erythropoietin group did not differ from those in control group.CT,1/2RT in model group were prolonged compared with that in control group and erythropoietin group(P0.01).Stimulated by the frequency of 10,20,40,60,100 Hz,diaphragm tension in model group was obviously decreased compared with that in control group and erythropoietin group(P0.01).SOD activity was decreased and MDA content was increased in model group compared with control group(P0.01),the difference of MDA was insignificant between control group and erythropoietin group(P0.05).Electron microscopy showed myofibrils were swollen and mitochondria were vacuolization in model group,erythropoietin can ameliorate the injury. Conclusions:Doxorubicin can depress the contraction of diaphragm and increase the production of oxygen free radicals and reduce their clearance;erythropoietin can protect diaphragm from damage by counteracting the above effects of doxorubicin.
Objective:To explore the mechanism of protective effect of erythropoietin on the doxorubicin induced diaphragm injury in rats. Methods:Thirty rats were divided into three groups: normal control group(n=10),model group(n=10) and erythropoietin group(n=10).Diaphragm strips was isolated to observe peak twitch tension(Pt),maximum titanic tension(Po),time to peak contraction(CT),half relaxation time(1/2RT),maximal rates of contraction(+dT/dtmax),maximal rates of relaxation(-dT/dtmax) and force-frequency curve.Meanwhile,the activity of superoxide dismutase(SOD) and content of malondialdehyde(MDA) in diaphragm were also measured.Electron microscope was used to observe the changes of diaphragm cell ultrastructure. Results:Pt,Po,+dT/dtmax,-dT/dtmax in model group were lower than those in control group(P0.01),the above four indexes in erythropoietin group did not differ from those in control group.CT,1/2RT in model group were prolonged compared with that in control group and erythropoietin group(P0.01).Stimulated by the frequency of 10,20,40,60,100 Hz,diaphragm tension in model group was obviously decreased compared with that in control group and erythropoietin group(P0.01).SOD activity was decreased and MDA content was increased in model group compared with control group(P0.01),the difference of MDA was insignificant between control group and erythropoietin group(P0.05).Electron microscopy showed myofibrils were swollen and mitochondria were vacuolization in model group,erythropoietin can ameliorate the injury. Conclusions:Doxorubicin can depress the contraction of diaphragm and increase the production of oxygen free radicals and reduce their clearance;erythropoietin can protect diaphragm from damage by counteracting the above effects of doxorubicin.
2012, 36(2): 142-144.
Abstract:
Objective:To investigate the effect of combination of esmolol and epinephrine on pulmonary edema,the concentration of troponin(cTnI) and the activity of malondialdehyde(MDA) after cardiopulmonary resuscitation(CPR) in rabbit model. Methods:Twenty six rabbits were allocated to three groups,alternating current(AC)-fibrillation model was performed.Group A(control group,only anesthesia,ventilation,and operation performed),Group B(0.01 mg/kg epinephrine) and Group C(0.01 mg/kg epinephrine with 0.2mg/kg esmolol).The ratio of lung wet-to-dry(W/D) weight was measured at 5 hours after CPR was performed,and the plasma level of cTnI and the activity of MDA were detected as well. Results:The ratio of W/D of group A,B and C increased at the 5th hour,cTnI and MDA after CPR,the differences were significant(P0.01-P0.05). Conclusions:Esmolol could reduce the myocardial injury and pulmonary edema in rabbit model after cardiac arrest.
Objective:To investigate the effect of combination of esmolol and epinephrine on pulmonary edema,the concentration of troponin(cTnI) and the activity of malondialdehyde(MDA) after cardiopulmonary resuscitation(CPR) in rabbit model. Methods:Twenty six rabbits were allocated to three groups,alternating current(AC)-fibrillation model was performed.Group A(control group,only anesthesia,ventilation,and operation performed),Group B(0.01 mg/kg epinephrine) and Group C(0.01 mg/kg epinephrine with 0.2mg/kg esmolol).The ratio of lung wet-to-dry(W/D) weight was measured at 5 hours after CPR was performed,and the plasma level of cTnI and the activity of MDA were detected as well. Results:The ratio of W/D of group A,B and C increased at the 5th hour,cTnI and MDA after CPR,the differences were significant(P0.01-P0.05). Conclusions:Esmolol could reduce the myocardial injury and pulmonary edema in rabbit model after cardiac arrest.
2012, 36(2): 145-148.
Abstract:
Objective:To construet the eukaryotie expression vector with human autophagy-related mic;rotubule ssociated protein 1
Objective:To construet the eukaryotie expression vector with human autophagy-related mic;rotubule ssociated protein 1
2012, 36(2): 148-150.
Abstract:
Objective:To investigate the expression of let-7b in breast cancer. Methods:Using tissue microarray platform and applying in situ molecular hybridization technique for detecting the expression of let-7b in 80 cases of human breast cancer,22 cases of benign breast disease. Results:The positive rates of let-7b was 35.0% in the breast cancer,it was lower than 59.1% in the benign breast disease(P0.05). Conclusions:Down-regulation of let-7b expression might play a role in the pathogenesis and progression of breast cancer.
Objective:To investigate the expression of let-7b in breast cancer. Methods:Using tissue microarray platform and applying in situ molecular hybridization technique for detecting the expression of let-7b in 80 cases of human breast cancer,22 cases of benign breast disease. Results:The positive rates of let-7b was 35.0% in the breast cancer,it was lower than 59.1% in the benign breast disease(P0.05). Conclusions:Down-regulation of let-7b expression might play a role in the pathogenesis and progression of breast cancer.
2012, 36(2): 151-153.
Abstract:
Objective:To evaluate the therapeutic efficacy of thrombus aspiration technique and thrombolysis of intracavitary and percutaneous transluminal angioplasty(PTA) for Budd-Chiari syndrome(BCS) complicated with inferior vena cava(IVC)thrombus. Methods:The clinical data of 11 cases of BCS complicated with IVC thrombus were collected.Venipuncture through femoral vein and inferior vena cavography were performed,and aspiration thrombus technique and thrombolysis of intracavitary were used to eliminate thrombus.After angiography of IVC,the recanalization of IVC was performed,which was followed by thrombus aspiration technique and thrombolysis of intracavitary.Finally,IVC was dilated with percutaneous transluminal balloon angioplasty.The clinical observation was used by color Doppler post-discharge. Results:All the patients occlusion was barrier diaphragm before operation,adopting this treatment,7 patients thrombus was eliminated instantly,after using intraductal thrombolysis,2 patients thrombus was eliminated 4 days later,2 patients thrombus was eliminated 7 days later.And pulmonary embolism was not happened with percutaneous transluminal balloon angioplasty.In following-up visit,blood current of IVC was continuous,there had no re-occlusion or thrombus happening. Conclusions:The therapeutic efficacy of thrombus aspiration technique and thrombolysis of intracavitary and PTA for BCS complicated with IVC thrombus is safe and effective.
Objective:To evaluate the therapeutic efficacy of thrombus aspiration technique and thrombolysis of intracavitary and percutaneous transluminal angioplasty(PTA) for Budd-Chiari syndrome(BCS) complicated with inferior vena cava(IVC)thrombus. Methods:The clinical data of 11 cases of BCS complicated with IVC thrombus were collected.Venipuncture through femoral vein and inferior vena cavography were performed,and aspiration thrombus technique and thrombolysis of intracavitary were used to eliminate thrombus.After angiography of IVC,the recanalization of IVC was performed,which was followed by thrombus aspiration technique and thrombolysis of intracavitary.Finally,IVC was dilated with percutaneous transluminal balloon angioplasty.The clinical observation was used by color Doppler post-discharge. Results:All the patients occlusion was barrier diaphragm before operation,adopting this treatment,7 patients thrombus was eliminated instantly,after using intraductal thrombolysis,2 patients thrombus was eliminated 4 days later,2 patients thrombus was eliminated 7 days later.And pulmonary embolism was not happened with percutaneous transluminal balloon angioplasty.In following-up visit,blood current of IVC was continuous,there had no re-occlusion or thrombus happening. Conclusions:The therapeutic efficacy of thrombus aspiration technique and thrombolysis of intracavitary and PTA for BCS complicated with IVC thrombus is safe and effective.
2012, 36(2): 153-156.
Abstract:
Objective:To evaluate the effectiveness and toxicity of concurrent chemoradiotherapy on locally advanced esophageal carcinoma. Methods:Forty-nine cases with locally advanced esophageal carcinoma were randomized into the first group(24 cases) treated only with radiotherapy and the second group(25 cases) treated with chemoradiotherapy combined cisplatin(20 mg/m2 day 1-4) and 5-fluorouracil(500 mg/m2 day 1-5).All cases were irradiated with60CO or 6MV-X ray.The radiation dose of the first group was 60-68 Gy in tumor for 30-34 times and sustained 6.0-6.5 weeks.The radiation dose of the second group was 54-60 Gy in tumor for 27-30 times and sustained 5.5-6.0 weeks,and 50-60 Gy,25-30 times and sustaining 5.0-6.0 weeks for regional lymph nodes.The second group were injected droply with 5-fluorouracil(500 mg/m2) for 5 days and cisplatin(20 mg/m2) for 4 days. Results:The effective rates of chemoradiotherapy group and radiotherapy group were 92.00% and 79.17%,respectively,the difference of the effective rates had no statistically significance(P0.05).The 1-year,2-year overall survival rate(OS) and locoregional progression-free survival(LPFS) of chemoradiotherapy group and radiotherapy group were 68.00%,32.00% and 58.33%,20.80%,and 72.00%,36.00% and 66.62%,25.00%,respectively.The LPFS and OS had no statistically significant difference between the two groups(P0.05).The toxicity of chemoradiotherapy group was heavier than the radiotherapy group,but the most patiens were tolerable. Conclusions:The chemoradiotherapy combined cisplatin and 5-fluorouracil can enhance the survival rate of patiens with locally advanced esophageal carcinoma and the adverse response is tolerable.
Objective:To evaluate the effectiveness and toxicity of concurrent chemoradiotherapy on locally advanced esophageal carcinoma. Methods:Forty-nine cases with locally advanced esophageal carcinoma were randomized into the first group(24 cases) treated only with radiotherapy and the second group(25 cases) treated with chemoradiotherapy combined cisplatin(20 mg/m2 day 1-4) and 5-fluorouracil(500 mg/m2 day 1-5).All cases were irradiated with60CO or 6MV-X ray.The radiation dose of the first group was 60-68 Gy in tumor for 30-34 times and sustained 6.0-6.5 weeks.The radiation dose of the second group was 54-60 Gy in tumor for 27-30 times and sustained 5.5-6.0 weeks,and 50-60 Gy,25-30 times and sustaining 5.0-6.0 weeks for regional lymph nodes.The second group were injected droply with 5-fluorouracil(500 mg/m2) for 5 days and cisplatin(20 mg/m2) for 4 days. Results:The effective rates of chemoradiotherapy group and radiotherapy group were 92.00% and 79.17%,respectively,the difference of the effective rates had no statistically significance(P0.05).The 1-year,2-year overall survival rate(OS) and locoregional progression-free survival(LPFS) of chemoradiotherapy group and radiotherapy group were 68.00%,32.00% and 58.33%,20.80%,and 72.00%,36.00% and 66.62%,25.00%,respectively.The LPFS and OS had no statistically significant difference between the two groups(P0.05).The toxicity of chemoradiotherapy group was heavier than the radiotherapy group,but the most patiens were tolerable. Conclusions:The chemoradiotherapy combined cisplatin and 5-fluorouracil can enhance the survival rate of patiens with locally advanced esophageal carcinoma and the adverse response is tolerable.
2012, 36(2): 157-159.
Abstract:
Objective:To investigate the expression of let-7b in breast cancer. Methods:Using tissue microarray platform and applying in situ molecular hybridization technique for detecting the expression of let-7b in 80 cases of human breast cancer,22 cases of benign breast disease. Results:The positive rates of let-7b was 35.0% in the breast cancer,it was lower than 59.1% in the benign breast disease(P0.05). Conclusions:Down-regulation of let-7b expression might play a role in the pathogenesis and progression of breast cancer.
Objective:To investigate the expression of let-7b in breast cancer. Methods:Using tissue microarray platform and applying in situ molecular hybridization technique for detecting the expression of let-7b in 80 cases of human breast cancer,22 cases of benign breast disease. Results:The positive rates of let-7b was 35.0% in the breast cancer,it was lower than 59.1% in the benign breast disease(P0.05). Conclusions:Down-regulation of let-7b expression might play a role in the pathogenesis and progression of breast cancer.
2012, 36(2): 160-162.
Abstract:
Objective:To evaluate the therapeutic efficacy of thrombus aspiration technique and thrombolysis of intracavitary and percutaneous transluminal angioplasty(PTA) for Budd-Chiari syndrome(BCS) complicated with inferior vena cava(IVC)thrombus. Methods:The clinical data of 11 cases of BCS complicated with IVC thrombus were collected.Venipuncture through femoral vein and inferior vena cavography were performed,and aspiration thrombus technique and thrombolysis of intracavitary were used to eliminate thrombus.After angiography of IVC,the recanalization of IVC was performed,which was followed by thrombus aspiration technique and thrombolysis of intracavitary.Finally,IVC was dilated with percutaneous transluminal balloon angioplasty.The clinical observation was used by color Doppler post-discharge. Results:All the patients occlusion was barrier diaphragm before operation,adopting this treatment,7 patients thrombus was eliminated instantly,after using intraductal thrombolysis,2 patients thrombus was eliminated 4 days later,2 patients thrombus was eliminated 7 days later.And pulmonary embolism was not happened with percutaneous transluminal balloon angioplasty.In following-up visit,blood current of IVC was continuous,there had no re-occlusion or thrombus happening. Conclusions:The therapeutic efficacy of thrombus aspiration technique and thrombolysis of intracavitary and PTA for BCS complicated with IVC thrombus is safe and effective.
Objective:To evaluate the therapeutic efficacy of thrombus aspiration technique and thrombolysis of intracavitary and percutaneous transluminal angioplasty(PTA) for Budd-Chiari syndrome(BCS) complicated with inferior vena cava(IVC)thrombus. Methods:The clinical data of 11 cases of BCS complicated with IVC thrombus were collected.Venipuncture through femoral vein and inferior vena cavography were performed,and aspiration thrombus technique and thrombolysis of intracavitary were used to eliminate thrombus.After angiography of IVC,the recanalization of IVC was performed,which was followed by thrombus aspiration technique and thrombolysis of intracavitary.Finally,IVC was dilated with percutaneous transluminal balloon angioplasty.The clinical observation was used by color Doppler post-discharge. Results:All the patients occlusion was barrier diaphragm before operation,adopting this treatment,7 patients thrombus was eliminated instantly,after using intraductal thrombolysis,2 patients thrombus was eliminated 4 days later,2 patients thrombus was eliminated 7 days later.And pulmonary embolism was not happened with percutaneous transluminal balloon angioplasty.In following-up visit,blood current of IVC was continuous,there had no re-occlusion or thrombus happening. Conclusions:The therapeutic efficacy of thrombus aspiration technique and thrombolysis of intracavitary and PTA for BCS complicated with IVC thrombus is safe and effective.
2012, 36(2): 163-165.
Abstract:
Objective:To evaluate the effectiveness and toxicity of concurrent chemoradiotherapy on locally advanced esophageal carcinoma. Methods:Forty-nine cases with locally advanced esophageal carcinoma were randomized into the first group(24 cases) treated only with radiotherapy and the second group(25 cases) treated with chemoradiotherapy combined cisplatin(20 mg/m2 day 1-4) and 5-fluorouracil(500 mg/m2 day 1-5).All cases were irradiated with60CO or 6MV-X ray.The radiation dose of the first group was 60-68 Gy in tumor for 30-34 times and sustained 6.0-6.5 weeks.The radiation dose of the second group was 54-60 Gy in tumor for 27-30 times and sustained 5.5-6.0 weeks,and 50-60 Gy,25-30 times and sustaining 5.0-6.0 weeks for regional lymph nodes.The second group were injected droply with 5-fluorouracil(500 mg/m2) for 5 days and cisplatin(20 mg/m2) for 4 days. Results:The effective rates of chemoradiotherapy group and radiotherapy group were 92.00% and 79.17%,respectively,the difference of the effective rates had no statistically significance(P0.05).The 1-year,2-year overall survival rate(OS) and locoregional progression-free survival(LPFS) of chemoradiotherapy group and radiotherapy group were 68.00%,32.00% and 58.33%,20.80%,and 72.00%,36.00% and 66.62%,25.00%,respectively.The LPFS and OS had no statistically significant difference between the two groups(P0.05).The toxicity of chemoradiotherapy group was heavier than the radiotherapy group,but the most patiens were tolerable. Conclusions:The chemoradiotherapy combined cisplatin and 5-fluorouracil can enhance the survival rate of patiens with locally advanced esophageal carcinoma and the adverse response is tolerable.
Objective:To evaluate the effectiveness and toxicity of concurrent chemoradiotherapy on locally advanced esophageal carcinoma. Methods:Forty-nine cases with locally advanced esophageal carcinoma were randomized into the first group(24 cases) treated only with radiotherapy and the second group(25 cases) treated with chemoradiotherapy combined cisplatin(20 mg/m2 day 1-4) and 5-fluorouracil(500 mg/m2 day 1-5).All cases were irradiated with60CO or 6MV-X ray.The radiation dose of the first group was 60-68 Gy in tumor for 30-34 times and sustained 6.0-6.5 weeks.The radiation dose of the second group was 54-60 Gy in tumor for 27-30 times and sustained 5.5-6.0 weeks,and 50-60 Gy,25-30 times and sustaining 5.0-6.0 weeks for regional lymph nodes.The second group were injected droply with 5-fluorouracil(500 mg/m2) for 5 days and cisplatin(20 mg/m2) for 4 days. Results:The effective rates of chemoradiotherapy group and radiotherapy group were 92.00% and 79.17%,respectively,the difference of the effective rates had no statistically significance(P0.05).The 1-year,2-year overall survival rate(OS) and locoregional progression-free survival(LPFS) of chemoradiotherapy group and radiotherapy group were 68.00%,32.00% and 58.33%,20.80%,and 72.00%,36.00% and 66.62%,25.00%,respectively.The LPFS and OS had no statistically significant difference between the two groups(P0.05).The toxicity of chemoradiotherapy group was heavier than the radiotherapy group,but the most patiens were tolerable. Conclusions:The chemoradiotherapy combined cisplatin and 5-fluorouracil can enhance the survival rate of patiens with locally advanced esophageal carcinoma and the adverse response is tolerable.
2012, 36(2): 165-167.
Abstract:
Objective:To observe the value of the fiberoptic bronchoscope in diagnosis and treatment of the bronchus foreign body. Methods:Twenty-four cases of bronchus foreign bodies which were diagnosed and treated bCy the fiberoptic bronchoscope were reviewed and analyzed retrospectivedly. Results:The main clinical manifestations were cough,expectoration,fever,hemoptysis,dyspnea,decreased breath sound and rhonchi of inspiration phase.Twelve cases were misdiagnosed out of our hospital,among which,4 were misdiagnosed as lung cancer,4 as pneumonia,2 as tuberculosis,1 as bronchial asthma and 1 as tuberculosis pleurisy.The foreign body in 17 cases was located in the right side of the lung and 7 cases in the left side;14 bronchus foreign bodies were of animality sort and 6 cases vegetality sort.All the foreign bodies were extirpated by the fiberoptic bronchoscope. Conclusions:The bronchus foreign body is easy to be misdiagnosed.The fiberoptic bronchoscope is of great value in diagnosis and treatment of the bronchus foreign body.
Objective:To observe the value of the fiberoptic bronchoscope in diagnosis and treatment of the bronchus foreign body. Methods:Twenty-four cases of bronchus foreign bodies which were diagnosed and treated bCy the fiberoptic bronchoscope were reviewed and analyzed retrospectivedly. Results:The main clinical manifestations were cough,expectoration,fever,hemoptysis,dyspnea,decreased breath sound and rhonchi of inspiration phase.Twelve cases were misdiagnosed out of our hospital,among which,4 were misdiagnosed as lung cancer,4 as pneumonia,2 as tuberculosis,1 as bronchial asthma and 1 as tuberculosis pleurisy.The foreign body in 17 cases was located in the right side of the lung and 7 cases in the left side;14 bronchus foreign bodies were of animality sort and 6 cases vegetality sort.All the foreign bodies were extirpated by the fiberoptic bronchoscope. Conclusions:The bronchus foreign body is easy to be misdiagnosed.The fiberoptic bronchoscope is of great value in diagnosis and treatment of the bronchus foreign body.
2012, 36(2): 168-170.
Abstract:
Objective:To explore the relationship of serum copeptin level and coronary heart disease(CHD),and its clinical significance. Methods:Coronary angiography(CAG)was performed in 94 hospitalized patients.According to coronary angiography findings,patients were divided into two groups:CHD group(n=71)and non-CHD group as control(n=23);the patients in CHD group were further divided into 3 subgroups:stable angina pectoris(SAP,n=20),unstable angina pectoris(UAP,n=19),and acute myocardial infarction(AMI,n=32);according to Gensinis score,the CHD group were further divided into 3 subgroups:mild stenosis group(n=18),moderate stenosis group(n=24),and severe stenosis group(n=29).According to the AMI patients with heart failure(HF) or not,the patients in AMI group were assigned into AMI group with HF(n=19)and AMI group without HF(n=13).Enzyme linked immunosorbent assay was adopted to detect the levels of copeptin from the serum of all patients. Results:Serum copeptin levels in CHD patients were significantly higher than those in normal control group(P0.01);serum copeptin levels in AMI patients and UAP group were significantly higher than those in control group and SAP group(P0.01);serum copeptin levels in severe stenosis patients were higher than those in control group,mild stenosis group,and moderate stenosis group(P0.01);comparing with AMI group without HF,copeptin levels in AMI group with HF were significantly higher(P0.01). Conclusions:Copeptin may be involved in stress response of patients with coronary heart disease,it may be correlated with the severity of coronary heart disease.Copeptin level is closely associated with pathology of coronary artery,it can warn the occurrence of coronary artery to happen.
Objective:To explore the relationship of serum copeptin level and coronary heart disease(CHD),and its clinical significance. Methods:Coronary angiography(CAG)was performed in 94 hospitalized patients.According to coronary angiography findings,patients were divided into two groups:CHD group(n=71)and non-CHD group as control(n=23);the patients in CHD group were further divided into 3 subgroups:stable angina pectoris(SAP,n=20),unstable angina pectoris(UAP,n=19),and acute myocardial infarction(AMI,n=32);according to Gensinis score,the CHD group were further divided into 3 subgroups:mild stenosis group(n=18),moderate stenosis group(n=24),and severe stenosis group(n=29).According to the AMI patients with heart failure(HF) or not,the patients in AMI group were assigned into AMI group with HF(n=19)and AMI group without HF(n=13).Enzyme linked immunosorbent assay was adopted to detect the levels of copeptin from the serum of all patients. Results:Serum copeptin levels in CHD patients were significantly higher than those in normal control group(P0.01);serum copeptin levels in AMI patients and UAP group were significantly higher than those in control group and SAP group(P0.01);serum copeptin levels in severe stenosis patients were higher than those in control group,mild stenosis group,and moderate stenosis group(P0.01);comparing with AMI group without HF,copeptin levels in AMI group with HF were significantly higher(P0.01). Conclusions:Copeptin may be involved in stress response of patients with coronary heart disease,it may be correlated with the severity of coronary heart disease.Copeptin level is closely associated with pathology of coronary artery,it can warn the occurrence of coronary artery to happen.
2012, 36(2): 171-173.
Abstract:
Objective:To investigate the changes of cell ultrastructure in colic mucosa in post infectious irritable bowel syndrome(IBS) through light microscopy and electron microscopy,and to elucidate their possible roles and clinical significance in intestinal mucosal barrier dysfunction. Methods:In 10 normal controls and 30 patients with post-infective IBS,biopsies were taken from the sigmoid colon.The ultrastructure of cells in colic mucosa and the changes of the mast cells in the paraffin-embedded sections were studied through transmission electron microscopy and analyzed by pathological image software. Results:The colic mucosa showed the integrity of epithelial cell membrane,normal cell shape,the regular distribution of microvilli of different length,developed rough endoplasmic reticulum.Many pieces of microvilli had broken.The aperture between cells were remarkably spacious.A large number of secretory granules,vacuoles were seen in the cytoplasm of goblet cells,mast cells and neuroendocrine cells. Conclusions:There were obvious changes on ultrastructure of cells in colic mucosa,which means IBS may be a gastrointestinal organic disease with ultrastrure alterations in colonic mucosa.The changes play a very important role in intestinal mucosal barrier dysfunction.
Objective:To investigate the changes of cell ultrastructure in colic mucosa in post infectious irritable bowel syndrome(IBS) through light microscopy and electron microscopy,and to elucidate their possible roles and clinical significance in intestinal mucosal barrier dysfunction. Methods:In 10 normal controls and 30 patients with post-infective IBS,biopsies were taken from the sigmoid colon.The ultrastructure of cells in colic mucosa and the changes of the mast cells in the paraffin-embedded sections were studied through transmission electron microscopy and analyzed by pathological image software. Results:The colic mucosa showed the integrity of epithelial cell membrane,normal cell shape,the regular distribution of microvilli of different length,developed rough endoplasmic reticulum.Many pieces of microvilli had broken.The aperture between cells were remarkably spacious.A large number of secretory granules,vacuoles were seen in the cytoplasm of goblet cells,mast cells and neuroendocrine cells. Conclusions:There were obvious changes on ultrastructure of cells in colic mucosa,which means IBS may be a gastrointestinal organic disease with ultrastrure alterations in colonic mucosa.The changes play a very important role in intestinal mucosal barrier dysfunction.
2012, 36(2): 173-175.
Abstract:
Objective:To investigate the health condition of the herdsmen and farmers in Tibet area,and to provide basis for the prevention and treatment of chronic and infectious diseases. Methods:One thousand six hundred and ninty-nine herdsmen and farmers were performed physical examinations including the routine inspection,chest perspective,electrocardiogram,B ultrasonic of the abdomen,routine blood and urine tests,measurement of the blood pressure,liver function,renal blood sugar,blood fat and hepatitis B surface antigen.Women were performed gynaecological check-up in addition. Results:Fifty-six point seven percent of the herdsmen and farmers had health problems including increased alanine aminotransferase(14.7%),biliary disease(13.2%),hemoglobin increasing disease(12.8%),hypertension(12.4%) and abnormal electrocardiogram(8.9%).The health problems were related with the education degree,and part of the diseases were related with the gender(such as hemoglobin increasing disease) or the age(such as hypertension). Conclusions:It is essential to strengthen the health education of the herdsmen and farmers,guide them to give up bad health habits,establish health records,regularize physical examinations and provide early intervention and treatment for the risk factors or diseases.
Objective:To investigate the health condition of the herdsmen and farmers in Tibet area,and to provide basis for the prevention and treatment of chronic and infectious diseases. Methods:One thousand six hundred and ninty-nine herdsmen and farmers were performed physical examinations including the routine inspection,chest perspective,electrocardiogram,B ultrasonic of the abdomen,routine blood and urine tests,measurement of the blood pressure,liver function,renal blood sugar,blood fat and hepatitis B surface antigen.Women were performed gynaecological check-up in addition. Results:Fifty-six point seven percent of the herdsmen and farmers had health problems including increased alanine aminotransferase(14.7%),biliary disease(13.2%),hemoglobin increasing disease(12.8%),hypertension(12.4%) and abnormal electrocardiogram(8.9%).The health problems were related with the education degree,and part of the diseases were related with the gender(such as hemoglobin increasing disease) or the age(such as hypertension). Conclusions:It is essential to strengthen the health education of the herdsmen and farmers,guide them to give up bad health habits,establish health records,regularize physical examinations and provide early intervention and treatment for the risk factors or diseases.
2012, 36(2): 176-179.
Abstract:
Objective:To observe the relationship between urinary albumin(UALB) and carotid atherosclerosis in cerebral infarction patients. Methods:One hundred patients with cerebral infarction were divided into 2 groups:UALB positive group(n=58) and UALB negative group(n=42).UALB excretion and ultrasonography for carotid artery were examined. Results:The common carotid artery intima media thickness,incidence rate of plaque were significantly higher in UALB positive group.The incidence rate of plaque was significantly higher when UALB exceeded the threshold of 60 mg/24 h(P0.05).The intima media thickness was positively related with the UALB,total cholesteral,and hemoglobin A1C,while the interior diameter was negatively with uric acid and UALB. Conclusions:High incidence of carotid atherosclerosis is happened in patients with positive UALB,especially when patients with UALB60 mg/24 h.
Objective:To observe the relationship between urinary albumin(UALB) and carotid atherosclerosis in cerebral infarction patients. Methods:One hundred patients with cerebral infarction were divided into 2 groups:UALB positive group(n=58) and UALB negative group(n=42).UALB excretion and ultrasonography for carotid artery were examined. Results:The common carotid artery intima media thickness,incidence rate of plaque were significantly higher in UALB positive group.The incidence rate of plaque was significantly higher when UALB exceeded the threshold of 60 mg/24 h(P0.05).The intima media thickness was positively related with the UALB,total cholesteral,and hemoglobin A1C,while the interior diameter was negatively with uric acid and UALB. Conclusions:High incidence of carotid atherosclerosis is happened in patients with positive UALB,especially when patients with UALB60 mg/24 h.
2012, 36(2): 179-182.
Abstract:
Objective:To explore the relationship between angiotensin-converting enzyme 2(ACE2) gene 9570A/G polymorphism and the severity of coronary artery stenosis in the Han population of northern Anhui province. Methods:The ACE2 gene polymorphism in 120 CHD patients was detected by means of polymerase chain reaction and restriction fragment length polymorphism;the frequency of genotype and allele were compared according to the number of coronary artery lesions and the dangerous scores. Results:The number of coronary artery lesions and Genisini scores in the male patients with G genotype were higher than those with A genotype in CHD group(P0.05);however,there was no statistical difference in female patients with CHD(P0.05). Conclusions:The ACE2 gene 9570A/G polymorphism might be associated with the severity of coronary artery straitness of CHD in male patients in the Han nationality of northern Anhui province;however,female patients might have no such correlation.
Objective:To explore the relationship between angiotensin-converting enzyme 2(ACE2) gene 9570A/G polymorphism and the severity of coronary artery stenosis in the Han population of northern Anhui province. Methods:The ACE2 gene polymorphism in 120 CHD patients was detected by means of polymerase chain reaction and restriction fragment length polymorphism;the frequency of genotype and allele were compared according to the number of coronary artery lesions and the dangerous scores. Results:The number of coronary artery lesions and Genisini scores in the male patients with G genotype were higher than those with A genotype in CHD group(P0.05);however,there was no statistical difference in female patients with CHD(P0.05). Conclusions:The ACE2 gene 9570A/G polymorphism might be associated with the severity of coronary artery straitness of CHD in male patients in the Han nationality of northern Anhui province;however,female patients might have no such correlation.
2012, 36(2): 183-186.
Abstract:
Objective:To investigate the therapeutic effect and safety of high-dose collagenase and ozone combined intradiscal injection for treatment of huge lumbar disc herniation. Methods:At first,48 patients with huge lumbar disc herniation was carried out lumbar discography.Second,the medical ozone 30-50 ml were injected into intradiscal space,the ozone at 50 mg/L.Third,if no abnormal happened for 10 minutes,1 800 u collagenase solved by 6 ml sodium chloride or 2 400 u collagenase solved by 8 ml sodium chloride was slowly injected into the lumbar disc. Results:The successful rate of discography and interventional therapy was 100%.Observation after 6-12 months of therapy showed that the cure rate and effective rate were 75.0%(36/48) and 16.7%(8/48),respectively.The overall excellent rate was 91.7%.The results of therapy were satisfied.No serious complications occurred in this group. Conclusions:Percutneous intradiscal combined injection of high-dose collagenase and ozone for treatment of huge lumbar disc herniation is an effective and safe method.
Objective:To investigate the therapeutic effect and safety of high-dose collagenase and ozone combined intradiscal injection for treatment of huge lumbar disc herniation. Methods:At first,48 patients with huge lumbar disc herniation was carried out lumbar discography.Second,the medical ozone 30-50 ml were injected into intradiscal space,the ozone at 50 mg/L.Third,if no abnormal happened for 10 minutes,1 800 u collagenase solved by 6 ml sodium chloride or 2 400 u collagenase solved by 8 ml sodium chloride was slowly injected into the lumbar disc. Results:The successful rate of discography and interventional therapy was 100%.Observation after 6-12 months of therapy showed that the cure rate and effective rate were 75.0%(36/48) and 16.7%(8/48),respectively.The overall excellent rate was 91.7%.The results of therapy were satisfied.No serious complications occurred in this group. Conclusions:Percutneous intradiscal combined injection of high-dose collagenase and ozone for treatment of huge lumbar disc herniation is an effective and safe method.
2012, 36(2): 186-188.
Abstract:
Objective:To observe the effects of nucleoside drugs combination therapy against decompensated period Hepatitis B liver cirrhosis. Methods:Sixty-eight cases with decompensated period Hepatitis B liver cirrhosis were divided into three groups randomly:based on the routine therapy,patients in A group were treated with lamivudine 100 mg/d and adefovir dipivoxil 10 mg/d;patients in B group were treated with lamivudine 100 mg/d,and with adefovir dipivoxil 10 mg/d in C group.After treatment for 48 weeks,the ALT recovery rate,HBeAg/anti-HBe sero-conversion rate,HBV DNA negative rate,and Child-pugh score were observed. Results:Through the antiviral treatment in these three groups,no death was happened.The ALT recovery rate in A group had a certain degree improvement with time,and in contrast to B and C group,the ALT recovery rate was increased significantly after 48 weeks treatment.The Child-pugh scores in all group had improved remarkably.HBeAg/anti-HBe sero-conversion rate in A,B,and C group was 20.83%,13.63% and 9.1%,respectively,there had no statistical differences among the three groups(P0.05).HBeAg negative rate in A,B,and C group was 62.5%,27.3% and 22.7%,in contrast to A group,there had significant differences about HBeAg negative rate in B and C group(P0.05). Conclusions:Lamivudine and adefovir dipivoxil combined antiviral treatment for decompensated period Hepatitis B liver cirrhosis can rapidly control the copy of HBV DNA,improve liver function effectively,delay the progress of disease,and finally achieve the treatment goal against liver cirrhosis.
Objective:To observe the effects of nucleoside drugs combination therapy against decompensated period Hepatitis B liver cirrhosis. Methods:Sixty-eight cases with decompensated period Hepatitis B liver cirrhosis were divided into three groups randomly:based on the routine therapy,patients in A group were treated with lamivudine 100 mg/d and adefovir dipivoxil 10 mg/d;patients in B group were treated with lamivudine 100 mg/d,and with adefovir dipivoxil 10 mg/d in C group.After treatment for 48 weeks,the ALT recovery rate,HBeAg/anti-HBe sero-conversion rate,HBV DNA negative rate,and Child-pugh score were observed. Results:Through the antiviral treatment in these three groups,no death was happened.The ALT recovery rate in A group had a certain degree improvement with time,and in contrast to B and C group,the ALT recovery rate was increased significantly after 48 weeks treatment.The Child-pugh scores in all group had improved remarkably.HBeAg/anti-HBe sero-conversion rate in A,B,and C group was 20.83%,13.63% and 9.1%,respectively,there had no statistical differences among the three groups(P0.05).HBeAg negative rate in A,B,and C group was 62.5%,27.3% and 22.7%,in contrast to A group,there had significant differences about HBeAg negative rate in B and C group(P0.05). Conclusions:Lamivudine and adefovir dipivoxil combined antiviral treatment for decompensated period Hepatitis B liver cirrhosis can rapidly control the copy of HBV DNA,improve liver function effectively,delay the progress of disease,and finally achieve the treatment goal against liver cirrhosis.
2012, 36(2): 189-191.
Abstract:
Objective:To compare the effects of combined spinal-epidural anesthesia(CSEA) and intravenous general anesthesia(IGA) during hip surgery. Methods:One hundred and twenty patients were evenly divided into two groups.One group received CSEA and the other IGA.The blood pressure,heart rate,pulse oxygen saturations and VAS marks of the two groups were recorded at 5 minutes after anesthesia,at the end of operation and at 1,6,12 and 24 hours after operation;the comfort level and the anesthesia cost were also compared. Results:The pain rate in CSEA group was much higher than that in IGA group(P0.01);the vital signs were normal in both groups during operation;the heart rate and blood pressure of CSE group were lower than those of IGA group within 12 hours after operation(P0.01),but the difference was not significant 12 and 24 hours later(P0.05);the VAS of CSEA group was obviously lower than that of IGA group within 6 hours after operation(P0.01);the anesthesia cost of CSEA group was much lower than that of IGA group(P0.01). Conclusions:Both of the anesthesia methods have their own advantages,and doctors should make a choice according to patients physical conditions.
Objective:To compare the effects of combined spinal-epidural anesthesia(CSEA) and intravenous general anesthesia(IGA) during hip surgery. Methods:One hundred and twenty patients were evenly divided into two groups.One group received CSEA and the other IGA.The blood pressure,heart rate,pulse oxygen saturations and VAS marks of the two groups were recorded at 5 minutes after anesthesia,at the end of operation and at 1,6,12 and 24 hours after operation;the comfort level and the anesthesia cost were also compared. Results:The pain rate in CSEA group was much higher than that in IGA group(P0.01);the vital signs were normal in both groups during operation;the heart rate and blood pressure of CSE group were lower than those of IGA group within 12 hours after operation(P0.01),but the difference was not significant 12 and 24 hours later(P0.05);the VAS of CSEA group was obviously lower than that of IGA group within 6 hours after operation(P0.01);the anesthesia cost of CSEA group was much lower than that of IGA group(P0.01). Conclusions:Both of the anesthesia methods have their own advantages,and doctors should make a choice according to patients physical conditions.
2012, 36(2): 192-193.
Abstract:
Objective:To explore the value of serum cystatin C(Cys C) in diagnosis of acute cerebral infarction(ACI). Methods:The serum level of Cys C,blood glucose and lipid in 60 cases of ACI and 40 healthy controls were detected,and a contrastive analysis was conducted.The relationship between the level of Cys C and the risk factors for cerebral infarction was analyzed. Results:The level of Cys C in the ACI group was higher than that in the healthy control group(P0.01).The serum level of Cys C was positively correlated with the blood glucose and the lipid. Conclusions:Serum Cys C combined with other factors participate in the genesis and development of cerebral infarction.Joint detection may be of help to the prediction,diagnosis and prognosis of ACI.
Objective:To explore the value of serum cystatin C(Cys C) in diagnosis of acute cerebral infarction(ACI). Methods:The serum level of Cys C,blood glucose and lipid in 60 cases of ACI and 40 healthy controls were detected,and a contrastive analysis was conducted.The relationship between the level of Cys C and the risk factors for cerebral infarction was analyzed. Results:The level of Cys C in the ACI group was higher than that in the healthy control group(P0.01).The serum level of Cys C was positively correlated with the blood glucose and the lipid. Conclusions:Serum Cys C combined with other factors participate in the genesis and development of cerebral infarction.Joint detection may be of help to the prediction,diagnosis and prognosis of ACI.
2012, 36(2): 194-196.
Abstract:
Objective:To assess the clinical value of hysteroscopy and ultrasonography in diagnosing the intrauterine abnormality in infertility women. Methods:The clinical data of 182 infertility women who had accepted hysteroscopy and ultrasound examination were analyzed retrospectively. Results:Intrauterine abnormality was detected in 88 of the cases by ultrasonography and 150 cases by hysteroscopy.There was significant difference between the two methods(P0.01).The common intrauterine abnormalities included endometrium polyp,cervical diseases,myoma,endometritis,uterine cavity adhesion and malformation of uterus. Conclusions:Hysteroscopy which is well acceptable and accurate is highly effective in detecting the intrauterine abnormality in infertility women when combined with ultrasonography.
Objective:To assess the clinical value of hysteroscopy and ultrasonography in diagnosing the intrauterine abnormality in infertility women. Methods:The clinical data of 182 infertility women who had accepted hysteroscopy and ultrasound examination were analyzed retrospectively. Results:Intrauterine abnormality was detected in 88 of the cases by ultrasonography and 150 cases by hysteroscopy.There was significant difference between the two methods(P0.01).The common intrauterine abnormalities included endometrium polyp,cervical diseases,myoma,endometritis,uterine cavity adhesion and malformation of uterus. Conclusions:Hysteroscopy which is well acceptable and accurate is highly effective in detecting the intrauterine abnormality in infertility women when combined with ultrasonography.
2012, 36(2): 196-197.
Abstract:
Objective:To investigate the efficacy of compound trabeculectomy in treatment of neovascular glaucoma. Methods:Thirteen cases(14 eyes) of neovascular glaucoma were treated by compound trabeculectomy.The anterior chamber depth,intraocular pressure,visual acuity and the complications were observed after operation.All the cases were followed up for 3 to 12 months. Results:No persistent shallow anterior chamber was observed.And postoperative complications including anterior chamber inflammation,hyphema and cornea disappeared after treatment.Postoperative intraocular pressure of the 14 cases was controlled between 10 and 24 mmHg.The visual acuity of 2 cases improved,and the others had no change. Conclusions:The compound trabeculectomy is safe,effective and economic in treatment of neovascular glaucoma.
Objective:To investigate the efficacy of compound trabeculectomy in treatment of neovascular glaucoma. Methods:Thirteen cases(14 eyes) of neovascular glaucoma were treated by compound trabeculectomy.The anterior chamber depth,intraocular pressure,visual acuity and the complications were observed after operation.All the cases were followed up for 3 to 12 months. Results:No persistent shallow anterior chamber was observed.And postoperative complications including anterior chamber inflammation,hyphema and cornea disappeared after treatment.Postoperative intraocular pressure of the 14 cases was controlled between 10 and 24 mmHg.The visual acuity of 2 cases improved,and the others had no change. Conclusions:The compound trabeculectomy is safe,effective and economic in treatment of neovascular glaucoma.
2012, 36(2): 198-199.
Abstract:
Objective:To explore the clinical value of carcinoma antigen 153(CA153) and malignant tumor specific growth factor(TSGF) in breast cancer diagnosis. Methods:The changes of serum CA153 and TSGF before and after treatment were detected by electrochemical luminescence method and chemical colorimetric method in 20 breast cancer patients,20 breast surgery patients with benign lesions,and 20 healthy controls. Results:In contrast to benign group and control group,there had statistical significances about the levels of serum CA153 and TSGF in malignant group(P0.05).There had statistical significances about the concentration of serum TSGF(P0.01),but no statistics about the concentration of CA153(P0.05) between benign group and control group.And there had no significant statistics between the two methods. Conclusions:The serum CA153 and TSGF tumor markers are valuable indicators in early detection of malignant tumors.
Objective:To explore the clinical value of carcinoma antigen 153(CA153) and malignant tumor specific growth factor(TSGF) in breast cancer diagnosis. Methods:The changes of serum CA153 and TSGF before and after treatment were detected by electrochemical luminescence method and chemical colorimetric method in 20 breast cancer patients,20 breast surgery patients with benign lesions,and 20 healthy controls. Results:In contrast to benign group and control group,there had statistical significances about the levels of serum CA153 and TSGF in malignant group(P0.05).There had statistical significances about the concentration of serum TSGF(P0.01),but no statistics about the concentration of CA153(P0.05) between benign group and control group.And there had no significant statistics between the two methods. Conclusions:The serum CA153 and TSGF tumor markers are valuable indicators in early detection of malignant tumors.
2012, 36(2): 210-212.
Abstract:
Objective:To analyze MRI diagnostic value in different period brain cysticercosis. Methods:The MRI appearance feature of 18 example brain cysticercosis in correspond brain cysticercosis diagnostic criteria were retrospectively analyzed. Results:According to MRI feature to take brain cysticercosis to divide three stage:bladder worm survival time(10 cases),scolex and capsule wall and hydatid fluid concomitance is characteristic,dot moderately signal inside round low signal in T1WI,capsular space shows high signal in T2WI;bladder worm denaturation time(5 cases),scolex vanishing and capsular space swollen and bladder surrounding appear oedema zone is characteristic,capsular space shows uneven low signal in T1WI;capsular space shows high signal in T2WI;bladder worm death time(3 cases),polypide death proceed calcify and fibering,equal signal or low signal in T1WI,small round low signal with sharply defined in T2WI; Conclusions:The MRI is an ideal method of diagnosis of every stage brain cysticercosis.MRI is able to reflect pathology process of brain cysticercosis,differential diagnosis and guide clinical therapy.
Objective:To analyze MRI diagnostic value in different period brain cysticercosis. Methods:The MRI appearance feature of 18 example brain cysticercosis in correspond brain cysticercosis diagnostic criteria were retrospectively analyzed. Results:According to MRI feature to take brain cysticercosis to divide three stage:bladder worm survival time(10 cases),scolex and capsule wall and hydatid fluid concomitance is characteristic,dot moderately signal inside round low signal in T1WI,capsular space shows high signal in T2WI;bladder worm denaturation time(5 cases),scolex vanishing and capsular space swollen and bladder surrounding appear oedema zone is characteristic,capsular space shows uneven low signal in T1WI;capsular space shows high signal in T2WI;bladder worm death time(3 cases),polypide death proceed calcify and fibering,equal signal or low signal in T1WI,small round low signal with sharply defined in T2WI; Conclusions:The MRI is an ideal method of diagnosis of every stage brain cysticercosis.MRI is able to reflect pathology process of brain cysticercosis,differential diagnosis and guide clinical therapy.
2012, 36(2): 213-215.
Abstract:
Objective:To evaluate the clinical values of 64-slice computed tomography coronary angiography(64SCTCA) in contrast to conventional coronary angiography(CCA). Methods:Thirty-five patients with 64SCTCA detected coronary artery stenosis were,using volume representation,surface reconstruction,maximum density projection techniques restructuring image shows the coronary artery main branch and the main branches,and X-ray coronary artery imaging(CCA) compared with the results of the analysis. Results:64SCTCA showed 90 lesions.Of them,85 lesions were consisted with CCA,22 lesions falsely positive and 10 lesions were fond by CCA not picked up by 64-slice CTCA.There was no obvious difference in the discovery of CAD between 64SCTCA and CCA. Conclusions: 64SCTCA has high accuracy in detecting coronary artery stenoses,as a noninvasive method,it can be used for screening patients with coronary artery diseases.
Objective:To evaluate the clinical values of 64-slice computed tomography coronary angiography(64SCTCA) in contrast to conventional coronary angiography(CCA). Methods:Thirty-five patients with 64SCTCA detected coronary artery stenosis were,using volume representation,surface reconstruction,maximum density projection techniques restructuring image shows the coronary artery main branch and the main branches,and X-ray coronary artery imaging(CCA) compared with the results of the analysis. Results:64SCTCA showed 90 lesions.Of them,85 lesions were consisted with CCA,22 lesions falsely positive and 10 lesions were fond by CCA not picked up by 64-slice CTCA.There was no obvious difference in the discovery of CAD between 64SCTCA and CCA. Conclusions: 64SCTCA has high accuracy in detecting coronary artery stenoses,as a noninvasive method,it can be used for screening patients with coronary artery diseases.
2012, 36(2): 216-218.
Abstract:
Objective:To explore the features and value of spiral CT in diagnosis of traumatic adrenal hematomas. Methods:The spiral CT pictures of 14 cases of adrenal hematomas were analyzed retrospectively. Results:Fifteen adrenal hematomas were found in 14 the cases,13 of which were on the right side and 1 was on both sides;4 cases were localized and 10 cases diffused.At the acute stage,the adrenal hematomas were round or oval with high-density;with time going,the adrenal hematomas became smaller and absorbed;enhanced scanning showed no strengthening or arced strengthening on the edge. Conclusions:Adrenal hematomas present typical CT manifestations,and spiral CT has great value for the diagnosis.Dynamic review and enhanced scanning may be of help to the differential diagnosis of adrenal hematomas
Objective:To explore the features and value of spiral CT in diagnosis of traumatic adrenal hematomas. Methods:The spiral CT pictures of 14 cases of adrenal hematomas were analyzed retrospectively. Results:Fifteen adrenal hematomas were found in 14 the cases,13 of which were on the right side and 1 was on both sides;4 cases were localized and 10 cases diffused.At the acute stage,the adrenal hematomas were round or oval with high-density;with time going,the adrenal hematomas became smaller and absorbed;enhanced scanning showed no strengthening or arced strengthening on the edge. Conclusions:Adrenal hematomas present typical CT manifestations,and spiral CT has great value for the diagnosis.Dynamic review and enhanced scanning may be of help to the differential diagnosis of adrenal hematomas
2012, 36(2): 219-222.
Abstract:
Objective:To comprehend the distribution of common pathogens and drug resistance in clinical infection,and provide the basis for rational use of antimicrobial drugs to clinicians. Methods:The statistical distribution of 602 strains of bacteria isolated from clinical samples in 2009 and the bacterial resistance rates of common infection were analyzed. Results:There were 134 strains of Gram-positive bacteria(22.26%),468 strains of Gram-negative bacteria(77.74%) in 602 strains of isolated bacteria.In Gram-positive bacteria infection,Staphylococcus epidermidis infection was more common(11.79%),followed by other streptococci(5.81%);while E.coli infection(29.57%) was at the top in Gram-negative bacteria infection,followed by Enterobacter(13.29%) and Klebsiella(12.46%).Drug susceptibility analysis revealed that Staphylococcus epidermidis was sensitive to novobiocin and ampicillin 100.00% and resistant to aztreonam,azithromycin and penicillin,the resistance rates were respectively 96.00%,96.00% and 92.42%.E.coli was sensitive to nitrofurantoin and 100.00% resistant to penicillin,rifampin and lincomycin. Conclusions:The drug resistant rates of penicillin,lincomycin and azithromycin were very high,the drug resistant rates of Gram-positive bacteria to ampicillin,vancomycin,novobiocin are low;the Gram-negative bacteria is the most sensitive to cefoperazone/sulbactam,tazobactam,piperacillin/tazobactam.
Objective:To comprehend the distribution of common pathogens and drug resistance in clinical infection,and provide the basis for rational use of antimicrobial drugs to clinicians. Methods:The statistical distribution of 602 strains of bacteria isolated from clinical samples in 2009 and the bacterial resistance rates of common infection were analyzed. Results:There were 134 strains of Gram-positive bacteria(22.26%),468 strains of Gram-negative bacteria(77.74%) in 602 strains of isolated bacteria.In Gram-positive bacteria infection,Staphylococcus epidermidis infection was more common(11.79%),followed by other streptococci(5.81%);while E.coli infection(29.57%) was at the top in Gram-negative bacteria infection,followed by Enterobacter(13.29%) and Klebsiella(12.46%).Drug susceptibility analysis revealed that Staphylococcus epidermidis was sensitive to novobiocin and ampicillin 100.00% and resistant to aztreonam,azithromycin and penicillin,the resistance rates were respectively 96.00%,96.00% and 92.42%.E.coli was sensitive to nitrofurantoin and 100.00% resistant to penicillin,rifampin and lincomycin. Conclusions:The drug resistant rates of penicillin,lincomycin and azithromycin were very high,the drug resistant rates of Gram-positive bacteria to ampicillin,vancomycin,novobiocin are low;the Gram-negative bacteria is the most sensitive to cefoperazone/sulbactam,tazobactam,piperacillin/tazobactam.
2012, 36(2): 222-223.
Abstract:
Objective:To explore the drug resistance and clinical distribution of Bauman acinetobacter,and provide a basis for controlling hospital infection. Methods:The clinical distribution,drug resistance and sample separation of 129 strains of Bauman acinetobacter were analysed,and the resistance rate of 14 kinds of commonly used antimicrobial agents were calculated. Results:Sputum specimens detection rate with 72.09% was highest,patients came mainly from physicians and intensive care treatment ward.The drug resistance rates of only 3 types of antimicrobial agents in 129 stains Bauman acinetobacter were less than 30%,imipenem,piperacillin/tazobactam and ampicillin/Shu TAZ were 24.80%,26.35% and 27.90%,respectively,the others drug resistance rates were more than 50%. Conclusions:As to the serious multi-drug resistance of Bauman acinetobacters,the resistance monitoring should be strengthened for directing clinical medication.
Objective:To explore the drug resistance and clinical distribution of Bauman acinetobacter,and provide a basis for controlling hospital infection. Methods:The clinical distribution,drug resistance and sample separation of 129 strains of Bauman acinetobacter were analysed,and the resistance rate of 14 kinds of commonly used antimicrobial agents were calculated. Results:Sputum specimens detection rate with 72.09% was highest,patients came mainly from physicians and intensive care treatment ward.The drug resistance rates of only 3 types of antimicrobial agents in 129 stains Bauman acinetobacter were less than 30%,imipenem,piperacillin/tazobactam and ampicillin/Shu TAZ were 24.80%,26.35% and 27.90%,respectively,the others drug resistance rates were more than 50%. Conclusions:As to the serious multi-drug resistance of Bauman acinetobacters,the resistance monitoring should be strengthened for directing clinical medication.
2012, 36(2): 224-225.
Abstract:
Objective:To evaluate the effect of case method in internal medicine instruction. Methods:The 2008 and 2009 clinical undergraduate classes in our college were divided into control group and experimental group.Case teaching method was applied to the experimental group,and the control group received the traditional approach.The quality of classroom teaching and curriculum test scores were taken as the evaluation index. Results:The curriculum test score of the experimental group was significantly higher than that of the control group(P0.01). Conclusions:Case method may efficiently increase the students interest in learning,cultivate their innovation ability and vivify the classroom atmosphere.
Objective:To evaluate the effect of case method in internal medicine instruction. Methods:The 2008 and 2009 clinical undergraduate classes in our college were divided into control group and experimental group.Case teaching method was applied to the experimental group,and the control group received the traditional approach.The quality of classroom teaching and curriculum test scores were taken as the evaluation index. Results:The curriculum test score of the experimental group was significantly higher than that of the control group(P0.01). Conclusions:Case method may efficiently increase the students interest in learning,cultivate their innovation ability and vivify the classroom atmosphere.
Email
RSS