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2013 Vol. 38, No. 2
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2013, 37(2): 125-128.
Abstract:
Objective:To provide microscopic anatomy of the transmastoid presigmoid sinus approach(TPA) in clinical research.Methods:Fifteen cadaveric specimens(30 sides) treated with 10% formaldehyde solution were selected for microscopic anatomy studies through simulating TPA.The space-occupying lesions of petroclival area of 5 cases were resected through TPA.Results:The distances from the suprameatal spine of external auditory canal which was defined as a basis points away transverse sinus-Sigmoid corner(TSC),semicircularis canalis,trigeminal notch,arcuate eminence,outer edge of internal acoustic pore and petrous apex were 13.782.72mm,(17.821.22)mm,(47.333.11)mm,(12.181.14)mm,(31.101.28)mm and(49.112.41)mm,respectively.The distances from the leading edge of TSC which was defined as a basis points away semicircularis canalis,trigeminal notch,arcuate eminence,outer edge of internal acoustic porise,petrous apex and the longest distance the cerebellum were(14.732.74)mm,(59.142.01)mm,(8.252.67)mm,(36.482.73) mm,(60.033.66)mm and(13.881.04)mm,respectively.Five cases with space-occupying lesions of petroclival area were resected,1 case with facial paralysis aggravated and preoperative symptoms of 4 cases disappeared and no complications.Conclusions:The relation of the surface markers of temporal bone rock and internal structure can guide surgery.TPA is good operation way in processing the petroclival area lesions.
Objective:To provide microscopic anatomy of the transmastoid presigmoid sinus approach(TPA) in clinical research.Methods:Fifteen cadaveric specimens(30 sides) treated with 10% formaldehyde solution were selected for microscopic anatomy studies through simulating TPA.The space-occupying lesions of petroclival area of 5 cases were resected through TPA.Results:The distances from the suprameatal spine of external auditory canal which was defined as a basis points away transverse sinus-Sigmoid corner(TSC),semicircularis canalis,trigeminal notch,arcuate eminence,outer edge of internal acoustic pore and petrous apex were 13.782.72mm,(17.821.22)mm,(47.333.11)mm,(12.181.14)mm,(31.101.28)mm and(49.112.41)mm,respectively.The distances from the leading edge of TSC which was defined as a basis points away semicircularis canalis,trigeminal notch,arcuate eminence,outer edge of internal acoustic porise,petrous apex and the longest distance the cerebellum were(14.732.74)mm,(59.142.01)mm,(8.252.67)mm,(36.482.73) mm,(60.033.66)mm and(13.881.04)mm,respectively.Five cases with space-occupying lesions of petroclival area were resected,1 case with facial paralysis aggravated and preoperative symptoms of 4 cases disappeared and no complications.Conclusions:The relation of the surface markers of temporal bone rock and internal structure can guide surgery.TPA is good operation way in processing the petroclival area lesions.
2013, 37(2): 129-130;133.
Abstract:
Objective:To investigate the effects of ketamine on haemodynamics in global cerebral ischemia reperfusion injury of rabbits.Methods:Fifteen adult healthy New Zealand white rabbits were randomly divided into control group(group A),model group(group B) and ketamine group(group C).The global cerebral ischemia reperfusion model of group B and C was established by two-vessel occlusion combined with femoral arterial bloodletting.The rabbits in group C were injected with ketamine by femoral vein after nipping bilateral common carotid arteries,and electroencephalogram(EEG),electrocardiogram(ECG),mean arterial blood pressure(MAP) and heart rate(HR) were monitored during operation.Results:Compared with group A,the HR of group B and C sped significantly up at 30 minutes after ischemia(P0.01),and the HR of group B was significantly lower than that in group A(P0.01) at 30 min after reperfusion.The MAP of group B were significantly lower than that in group A and C(P0.01) at 30 min after ischemia,and began to rise at 30 mins after reperfusion and was still less than basic value(P0.01).The EEG of group C was significantly higher than that in group A and B at 30 mins after ischemia and reperfusion(P0.01).The HR of group C was significantly higher than that in group B at 30 min after ischemia(P0.01),and HR at 30 mins after reperfusion of group C were significantly higher than that in group B(P0.01).Conclusions:Ketamine can maintain the haemodynamic stability of rabbit global cerebral ischemia reperfusion injury,which can effectively alleviate and reduce brain injury caused by ischemia reperfusion.
Objective:To investigate the effects of ketamine on haemodynamics in global cerebral ischemia reperfusion injury of rabbits.Methods:Fifteen adult healthy New Zealand white rabbits were randomly divided into control group(group A),model group(group B) and ketamine group(group C).The global cerebral ischemia reperfusion model of group B and C was established by two-vessel occlusion combined with femoral arterial bloodletting.The rabbits in group C were injected with ketamine by femoral vein after nipping bilateral common carotid arteries,and electroencephalogram(EEG),electrocardiogram(ECG),mean arterial blood pressure(MAP) and heart rate(HR) were monitored during operation.Results:Compared with group A,the HR of group B and C sped significantly up at 30 minutes after ischemia(P0.01),and the HR of group B was significantly lower than that in group A(P0.01) at 30 min after reperfusion.The MAP of group B were significantly lower than that in group A and C(P0.01) at 30 min after ischemia,and began to rise at 30 mins after reperfusion and was still less than basic value(P0.01).The EEG of group C was significantly higher than that in group A and B at 30 mins after ischemia and reperfusion(P0.01).The HR of group C was significantly higher than that in group B at 30 min after ischemia(P0.01),and HR at 30 mins after reperfusion of group C were significantly higher than that in group B(P0.01).Conclusions:Ketamine can maintain the haemodynamic stability of rabbit global cerebral ischemia reperfusion injury,which can effectively alleviate and reduce brain injury caused by ischemia reperfusion.
2013, 37(2): 131-133;130.
Abstract:
Objective:To establish a herpes simplex virus encephalitis(HSE) model in Balb/c mouse.Methods:Forty Balb/c mice were intracerebrally or intranasally inoculated with(herpes simplex virus type 1,HSV-1)F strain 104 plaque forming unit(PFU,titer=3.5105/ml),another twenty mice were intracerebrally or intranasally inoculated with saline as control,separately.The ethological and pathological changes were evaluated.Results:The Balb/c mouse which intracerebrally inoculated with HSV-1 exhibited different symptoms such as hair disorder,downcast,agitation,seizure and death,etc.These mice showed clinical feature as early as 3 days after inoculation,which reached peak at 7-10 days,and recovered after 14 days.Some mice were died at the 6th day.The pathological changes included inflammatory cell infiltration of meninges and parenchyma,neurons necrosis,lymphocytic muff around the vessel and microglia proliferation,etc.Only one mouse in intranasal inoculation group was shown mild hair disorder.The ethological and pathological changes were not observed in each control group.The morbidity of intracerebral inoculation group was obviously higher than the intranasal inoculation group and the control group(P0.01).Conclusions:Inoculation of HSV-1 F strain 104 PFU in Balb/c mouse intracerebrally can establish a stable HSE model.
Objective:To establish a herpes simplex virus encephalitis(HSE) model in Balb/c mouse.Methods:Forty Balb/c mice were intracerebrally or intranasally inoculated with(herpes simplex virus type 1,HSV-1)F strain 104 plaque forming unit(PFU,titer=3.5105/ml),another twenty mice were intracerebrally or intranasally inoculated with saline as control,separately.The ethological and pathological changes were evaluated.Results:The Balb/c mouse which intracerebrally inoculated with HSV-1 exhibited different symptoms such as hair disorder,downcast,agitation,seizure and death,etc.These mice showed clinical feature as early as 3 days after inoculation,which reached peak at 7-10 days,and recovered after 14 days.Some mice were died at the 6th day.The pathological changes included inflammatory cell infiltration of meninges and parenchyma,neurons necrosis,lymphocytic muff around the vessel and microglia proliferation,etc.Only one mouse in intranasal inoculation group was shown mild hair disorder.The ethological and pathological changes were not observed in each control group.The morbidity of intracerebral inoculation group was obviously higher than the intranasal inoculation group and the control group(P0.01).Conclusions:Inoculation of HSV-1 F strain 104 PFU in Balb/c mouse intracerebrally can establish a stable HSE model.
2013, 37(2): 134-136.
Abstract:
Objective:To explore the expression of toll-like receptor 4(TLR4) and tumor necrosis facor-(TNF-) and analyse their relationships in rat colon tissue with ulcerative colitis(UC),and investigate the significance of TLR4 signaling pathway in the pathogenesis of UC.Methods:Eighty SD rats were randomly divided into control group(20 rats) and model group(60 rats) which were made model using trinitrobenzene sulfonic acid and ethanol.The morphology and histological changes in the model group were observed.The expression of TLR4 and TNF- in colonic mucosa in two groups were measured using immunohistochemistry.Results:The successful rate of making model was 97%.The expression rates of TLR4 and TNF- protein in UC colon epithelium cells and inflammatory cells were 84.5% and 89.7% respectively,which were higher than that of the control group of 30.0% and 20.0%(P0.01).The expression of TLR4 and TNF- in colonic mucosa in the model group were significantly enhanced with histological grade increasing and its were a positive relationship(P0.01).Conclusions:The expressions of TLR4 and TNF- have some relation to the occurrence and development of UC.
Objective:To explore the expression of toll-like receptor 4(TLR4) and tumor necrosis facor-(TNF-) and analyse their relationships in rat colon tissue with ulcerative colitis(UC),and investigate the significance of TLR4 signaling pathway in the pathogenesis of UC.Methods:Eighty SD rats were randomly divided into control group(20 rats) and model group(60 rats) which were made model using trinitrobenzene sulfonic acid and ethanol.The morphology and histological changes in the model group were observed.The expression of TLR4 and TNF- in colonic mucosa in two groups were measured using immunohistochemistry.Results:The successful rate of making model was 97%.The expression rates of TLR4 and TNF- protein in UC colon epithelium cells and inflammatory cells were 84.5% and 89.7% respectively,which were higher than that of the control group of 30.0% and 20.0%(P0.01).The expression of TLR4 and TNF- in colonic mucosa in the model group were significantly enhanced with histological grade increasing and its were a positive relationship(P0.01).Conclusions:The expressions of TLR4 and TNF- have some relation to the occurrence and development of UC.
2013, 37(2): 137-141;138.
Abstract:
Objective:To compare the dosage of propofol and the time of patient revival and extubation of general anesthesia combined with epidural block and general anesthesia at the same degree of anesthesia.Methods:Forty patients scheduled for epigastric surgery were randomly into general anesthesia(GA group) and general anesthesia combined with epidural block(GEA group).Epidural puncture was performed in GEA group after general anesthesia.Tracheal intubation of two groups were performed at the 40 to 50 of bispectral index(BIS).Propofol was maintained at 40 to 60 of BIS during operation.The time of postoperative revival and extubation,and the total dosage of propofol and sufentanil were recorded.Results:Compared with GA group,the total dosage of propofol and sufentanil in GEA group were less(P0.01),the time of postoperative revival and extubation in GEA group were shorter(P0.01).Conclusions:At the same degree of anesthesia,GEA can decrease the total dosage of propofol and sufentanil,and short the time of postoperative revival and extubation.
Objective:To compare the dosage of propofol and the time of patient revival and extubation of general anesthesia combined with epidural block and general anesthesia at the same degree of anesthesia.Methods:Forty patients scheduled for epigastric surgery were randomly into general anesthesia(GA group) and general anesthesia combined with epidural block(GEA group).Epidural puncture was performed in GEA group after general anesthesia.Tracheal intubation of two groups were performed at the 40 to 50 of bispectral index(BIS).Propofol was maintained at 40 to 60 of BIS during operation.The time of postoperative revival and extubation,and the total dosage of propofol and sufentanil were recorded.Results:Compared with GA group,the total dosage of propofol and sufentanil in GEA group were less(P0.01),the time of postoperative revival and extubation in GEA group were shorter(P0.01).Conclusions:At the same degree of anesthesia,GEA can decrease the total dosage of propofol and sufentanil,and short the time of postoperative revival and extubation.
2013, 37(2): 139-141;138.
Abstract:
Objective:To summarize the experience of diagnosis and surgical treatment in 65 cases with cardiac myxomas for improving the curative effects.Methods:The cardiac myxomas were resected all 65 cases under cardiac pulmonary bypass anesthesia.Under the condition of heartbeat,the aortas of 44 cases and superior inferior vena of 21 cases were blocked.The operation paths of cardiac myxomas location in right atrium and left atrium were through right atrium and right atrium atrial septum,respectively.The atrial septal defects of 31 cases were sutured by dacron patch and other cases were sutured directly.Tricuspid and mitral valve plasty were performed in 5 and 1 patients,respectively.Results: All patients were diagnosed by echocardiography in preoperation,confirmed by the surgery and pathology and discharged from hospital after recovery.The heart function of 63 and 2 cases were recoverd to NYHA Ⅰ and Ⅱ,respectively,during the period of the follow-up for 3 months to 15 years.One case with cardiac myxomas recurred 2 years after surgery,who was cured through the second operation.The recurrence rate was 1.54%.Conclusions: Ecocardiography is an effective and simple way to diagnose the cardiac myxomas.The early operation as soon as possible and radical resection are the key to prevent recurrence and postoperative follow-up must be reinforced.
Objective:To summarize the experience of diagnosis and surgical treatment in 65 cases with cardiac myxomas for improving the curative effects.Methods:The cardiac myxomas were resected all 65 cases under cardiac pulmonary bypass anesthesia.Under the condition of heartbeat,the aortas of 44 cases and superior inferior vena of 21 cases were blocked.The operation paths of cardiac myxomas location in right atrium and left atrium were through right atrium and right atrium atrial septum,respectively.The atrial septal defects of 31 cases were sutured by dacron patch and other cases were sutured directly.Tricuspid and mitral valve plasty were performed in 5 and 1 patients,respectively.Results: All patients were diagnosed by echocardiography in preoperation,confirmed by the surgery and pathology and discharged from hospital after recovery.The heart function of 63 and 2 cases were recoverd to NYHA Ⅰ and Ⅱ,respectively,during the period of the follow-up for 3 months to 15 years.One case with cardiac myxomas recurred 2 years after surgery,who was cured through the second operation.The recurrence rate was 1.54%.Conclusions: Ecocardiography is an effective and simple way to diagnose the cardiac myxomas.The early operation as soon as possible and radical resection are the key to prevent recurrence and postoperative follow-up must be reinforced.
2013, 37(2): 142-145.
Abstract:
Objective:To explore the clinical significance and expressions of hypoxia-induced factor-1(HIF-1) and carbonic anhydrase Ⅸ(CAⅨ) in cervical squamous cell carcinoma(SCC).Methods:The expression characteristics and correlations of HIF-1 and CAⅨ in normal cervical tissues of 30 cases,cervical intraepithelial neoplasia(CIN) of 55 cases and SCC tissues of 80 cases were detected by immunohistochemistry of EliVision Plus/HRP.Results:The positive expression rates of HIF-1 in normal cervical tissues,CIN tissues and SCC tissues were increased gradually,whose were 0.00%,43.64% and 76.25%,respectively,and their differences were statistical significant(P0.01).The positive expression rates of CAⅨ in normal cervical tissues,CIN tissues and SCC tissues were increased gradually,whose were 0.00%,40.00% and 66.25%,respectively,and their differences were statistical significant(P0.01).The expression rates of HIF-1 and CAⅨ in poorly differentiated SCC were significantly higher than those in well or moderated differentiated SCC(P0.05).The expression rates of HIF-1 and CAⅨ in SCC with lymph node metastasis were significantly higher than those in SCC without lymph node metastasis(P0.05).The HIF-1 expression rates in SCC of clinical stage Ⅱ were significantly higher than those in clinical stage Ⅰ(P0.05).The expression of HIF-1 was significantly related to the CAⅨ expression in SCC(P0.05).Conclusions:HIF-1 and CAⅨ play an important role in the occurrence and development of SCC.The high expression and postive correlations of HIF-1 and CAⅨ in cervical SCC suggest the feasibility of the targeted molecular therapy based on the pathway induced by hypoxia factor for treatment of SCC.
Objective:To explore the clinical significance and expressions of hypoxia-induced factor-1(HIF-1) and carbonic anhydrase Ⅸ(CAⅨ) in cervical squamous cell carcinoma(SCC).Methods:The expression characteristics and correlations of HIF-1 and CAⅨ in normal cervical tissues of 30 cases,cervical intraepithelial neoplasia(CIN) of 55 cases and SCC tissues of 80 cases were detected by immunohistochemistry of EliVision Plus/HRP.Results:The positive expression rates of HIF-1 in normal cervical tissues,CIN tissues and SCC tissues were increased gradually,whose were 0.00%,43.64% and 76.25%,respectively,and their differences were statistical significant(P0.01).The positive expression rates of CAⅨ in normal cervical tissues,CIN tissues and SCC tissues were increased gradually,whose were 0.00%,40.00% and 66.25%,respectively,and their differences were statistical significant(P0.01).The expression rates of HIF-1 and CAⅨ in poorly differentiated SCC were significantly higher than those in well or moderated differentiated SCC(P0.05).The expression rates of HIF-1 and CAⅨ in SCC with lymph node metastasis were significantly higher than those in SCC without lymph node metastasis(P0.05).The HIF-1 expression rates in SCC of clinical stage Ⅱ were significantly higher than those in clinical stage Ⅰ(P0.05).The expression of HIF-1 was significantly related to the CAⅨ expression in SCC(P0.05).Conclusions:HIF-1 and CAⅨ play an important role in the occurrence and development of SCC.The high expression and postive correlations of HIF-1 and CAⅨ in cervical SCC suggest the feasibility of the targeted molecular therapy based on the pathway induced by hypoxia factor for treatment of SCC.
2013, 37(2): 145-148.
Abstract:
Objective:To investigate the clinicopathologic characteristics of breast neuroendocrine carcinoma.Methods:The breast neuroendocrine carcinoma tissue of 3 cases were examined by histopathology and immunohistochemistry and relevant literatures were reviewed.Results:Three female cases with 1.5 to 4.5 cm of tumor sizes in diameter were 47 to 57 years old.The morphological types of these tumors included solid carcinoma in 2 cases and small cell carcinoma in 1 case.The synaptophysin expression of tumor cells of all cases were stained positive,but the positive expression of chromogranin,cytokeratin and NCAM1 of tumor cells of 2 cases were verified.Two cases were alive except one cases death from small cell carcinoma.Conclusions:The breast neuroendocrine carcinoma is a rare type of the breast carcinoma,whose diagnosis should mainly rely on the pathological and histological examination.
Objective:To investigate the clinicopathologic characteristics of breast neuroendocrine carcinoma.Methods:The breast neuroendocrine carcinoma tissue of 3 cases were examined by histopathology and immunohistochemistry and relevant literatures were reviewed.Results:Three female cases with 1.5 to 4.5 cm of tumor sizes in diameter were 47 to 57 years old.The morphological types of these tumors included solid carcinoma in 2 cases and small cell carcinoma in 1 case.The synaptophysin expression of tumor cells of all cases were stained positive,but the positive expression of chromogranin,cytokeratin and NCAM1 of tumor cells of 2 cases were verified.Two cases were alive except one cases death from small cell carcinoma.Conclusions:The breast neuroendocrine carcinoma is a rare type of the breast carcinoma,whose diagnosis should mainly rely on the pathological and histological examination.
2013, 37(2): 149-150;153;150.
Abstract:
Objective:To investigate the effects of traditional Chinese medicine Shuganjianpi mixture on patients with liver cirrhosis.Methods:Sixty liver cirrhosis patients determined by traditional Chinese physicians as the type of stagnation of liver-QI with deficiency of the spleen were randomly divided into treatment group and control group.The patients in the control group were injected with Diammonium glycyrrhizinate and compound danshen injection once a day and the treatment group received oral administration of Shuganjianpi mixture twice a day in addition to the above therapy.The therapy lasted for 30 days in both groups.The ALT,ALB,TBI and serum PRL level in all the patients were determined before and after the treatment.Results:The ALT,ALB,TBI and PRL levels in both groups had no significant difference before treatment(P0.05);after the therapy,the ALT in the control group and the ALT,ALB,TBI and PRL levels in the treatment group changed significantly(P0.05 to P0.01).Conclusions:The traditional Chinese medicine Shuganjianpi mixture can decrease the serum level of PRL in posthepatitic cirrhosis patients determined as type of stagnation of liver-QI with deficiency of the spleen.
Objective:To investigate the effects of traditional Chinese medicine Shuganjianpi mixture on patients with liver cirrhosis.Methods:Sixty liver cirrhosis patients determined by traditional Chinese physicians as the type of stagnation of liver-QI with deficiency of the spleen were randomly divided into treatment group and control group.The patients in the control group were injected with Diammonium glycyrrhizinate and compound danshen injection once a day and the treatment group received oral administration of Shuganjianpi mixture twice a day in addition to the above therapy.The therapy lasted for 30 days in both groups.The ALT,ALB,TBI and serum PRL level in all the patients were determined before and after the treatment.Results:The ALT,ALB,TBI and PRL levels in both groups had no significant difference before treatment(P0.05);after the therapy,the ALT in the control group and the ALT,ALB,TBI and PRL levels in the treatment group changed significantly(P0.05 to P0.01).Conclusions:The traditional Chinese medicine Shuganjianpi mixture can decrease the serum level of PRL in posthepatitic cirrhosis patients determined as type of stagnation of liver-QI with deficiency of the spleen.
2013, 37(2): 151-153;150.
Abstract:
Objective:To investigate the effects of dezocine preemptive analgesia on cardiorespiratory and recovery time of painless induced abortion with propofol.Methods:Sixty cases with painless induced abortion were randomly divided into group A,B and C.Group A,B and C were injected the same volume normal saline,fentanyl(1 g/kg) and dezocine(0.05 mg/kg) at the time of 5 minutes before sterilizing respectively and 2 mg/kg of propofol were injected after sterilizing.Operation began after patients consciousness disappear,and 20-40 mg of propofol were added as needed.The data of basic value(T1),after anesthesia(T2),surgery(T3) and after surgery(T4),the operation and awakening time,the dosage of propofol and the grade of anesthesia effect were mesured.Results:The HR in group C postoperation were significantly lower that of preoperation(P0.05),but without further treatment.At T2,the values of SpO2 in group B were significantly lower than that in other two group(P0.01).The propofol consumption in group A were maximum,the recovery time in group C were the shortest and the anesthetic effects of group A were worse than that of group B and C(P0.05).Conclusions:Compared with the effects of alone propofol,the application of dezocine combined with in painless induced abortion is safety and effect,which is worthy to be popularized.
Objective:To investigate the effects of dezocine preemptive analgesia on cardiorespiratory and recovery time of painless induced abortion with propofol.Methods:Sixty cases with painless induced abortion were randomly divided into group A,B and C.Group A,B and C were injected the same volume normal saline,fentanyl(1 g/kg) and dezocine(0.05 mg/kg) at the time of 5 minutes before sterilizing respectively and 2 mg/kg of propofol were injected after sterilizing.Operation began after patients consciousness disappear,and 20-40 mg of propofol were added as needed.The data of basic value(T1),after anesthesia(T2),surgery(T3) and after surgery(T4),the operation and awakening time,the dosage of propofol and the grade of anesthesia effect were mesured.Results:The HR in group C postoperation were significantly lower that of preoperation(P0.05),but without further treatment.At T2,the values of SpO2 in group B were significantly lower than that in other two group(P0.01).The propofol consumption in group A were maximum,the recovery time in group C were the shortest and the anesthetic effects of group A were worse than that of group B and C(P0.05).Conclusions:Compared with the effects of alone propofol,the application of dezocine combined with in painless induced abortion is safety and effect,which is worthy to be popularized.
2013, 37(2): 154-155;159;155.
Abstract:
Objective:To investigate the significances of the serum level changes of vascular endothelial growth factor(VEGF) and carbohydrate antigen 199(CA199) in patients with gastric cancer before and after chemotherapy.Methods:The serum levels of VEGF and CA199 of 40 cases with gastric cancer were measured by ELISA,and which were compared with those in forty healthy people.Results:The serum levels of VEGF and CA199 in gastric carcinoma patients were significantly higher than those in the healthy people before chemotherapy(P0.01),but the serum levels in complete remission and partial remission patients in 8 weeks post-chemotherapy were significantly lower than those in pre-chemotherapy(P0.01).The VEGF levels in the stable treatment patients had no statistical significance(P0.05),and the CA199 levels were lower than that of before chemotherapy(P0.01).The serum levels of VEGF and CA199 in the progress group were higher than those of before treatment and existed the positive correlation(P0.01).Conclusions:The serum levels of VEGF and CA199 in patients with gastric cancer are important parameters for early diagnosis and evaluating treatment effects.
Objective:To investigate the significances of the serum level changes of vascular endothelial growth factor(VEGF) and carbohydrate antigen 199(CA199) in patients with gastric cancer before and after chemotherapy.Methods:The serum levels of VEGF and CA199 of 40 cases with gastric cancer were measured by ELISA,and which were compared with those in forty healthy people.Results:The serum levels of VEGF and CA199 in gastric carcinoma patients were significantly higher than those in the healthy people before chemotherapy(P0.01),but the serum levels in complete remission and partial remission patients in 8 weeks post-chemotherapy were significantly lower than those in pre-chemotherapy(P0.01).The VEGF levels in the stable treatment patients had no statistical significance(P0.05),and the CA199 levels were lower than that of before chemotherapy(P0.01).The serum levels of VEGF and CA199 in the progress group were higher than those of before treatment and existed the positive correlation(P0.01).Conclusions:The serum levels of VEGF and CA199 in patients with gastric cancer are important parameters for early diagnosis and evaluating treatment effects.
2013, 37(2): 156-159;155.
Abstract:
Objective:To explore the clinical effects of preoperative indwelling catheter on the photoselective vaporization of prostate(PVP).Methods:Sixty patients with benign prostatic hyperplasia and acute urinary retention were indwelled catheter and randomly divided into two groups,which included accepting PVP surgery directly after removal the catheter(groupⅠ,30 cases) and treatment with anti-inflammatory and oral medication to inhibit prostatic hyperplasia and accepting PVP surgery 2 weeks after removal the catheter(group Ⅱ).The operative time,intraoperative bleeding,postoperative indwelling catheter time,postoperative hospital stay,postoperative bladder irrigation time and the hemoglobin content before and after surgery of two groups were analyzed.The international prostate symptom score(IPSS),life quality score(QOL),maximum flow rate(Qmax),residual urine volume(RUV) and variety of complications were followed-up and recorded.Results:The postoperative hemoglobin contents of two groups had significant statistical difference(P0.05).The operative time,intraoperative bleeding,postoperative indwelling catheter time,postoperative hospital stay and the postoperative bladder irrigation time of group Ⅰ were longer than that of group Ⅱ(P0.05 to P0.01).Compared with preoperative,the IPSS,QOL,Qmax and RUV of two groups in 1 week,3 and 6 mouths after operation were significantly improved,but the difference had no statistically significant(P0.05).Conclusions:PVP surgery is safe and reliable.Preoperative indwelling catheter has some effects on operation,which can lead to much bleeding during operation,vision blurry and prolong operative time,and no significantly effects on postoperative.
Objective:To explore the clinical effects of preoperative indwelling catheter on the photoselective vaporization of prostate(PVP).Methods:Sixty patients with benign prostatic hyperplasia and acute urinary retention were indwelled catheter and randomly divided into two groups,which included accepting PVP surgery directly after removal the catheter(groupⅠ,30 cases) and treatment with anti-inflammatory and oral medication to inhibit prostatic hyperplasia and accepting PVP surgery 2 weeks after removal the catheter(group Ⅱ).The operative time,intraoperative bleeding,postoperative indwelling catheter time,postoperative hospital stay,postoperative bladder irrigation time and the hemoglobin content before and after surgery of two groups were analyzed.The international prostate symptom score(IPSS),life quality score(QOL),maximum flow rate(Qmax),residual urine volume(RUV) and variety of complications were followed-up and recorded.Results:The postoperative hemoglobin contents of two groups had significant statistical difference(P0.05).The operative time,intraoperative bleeding,postoperative indwelling catheter time,postoperative hospital stay and the postoperative bladder irrigation time of group Ⅰ were longer than that of group Ⅱ(P0.05 to P0.01).Compared with preoperative,the IPSS,QOL,Qmax and RUV of two groups in 1 week,3 and 6 mouths after operation were significantly improved,but the difference had no statistically significant(P0.05).Conclusions:PVP surgery is safe and reliable.Preoperative indwelling catheter has some effects on operation,which can lead to much bleeding during operation,vision blurry and prolong operative time,and no significantly effects on postoperative.
2013, 37(2): 160-162.
Abstract:
Objective:To investigate the clinical value of three-dimensional CT reconstruction and titanium mesh digital computer in repairing skull defects.Methods:Sixty-eight cases with skull defect were treated with titanium mesh through CT 3D reconstruction.Results:Sixty-four cases healed with beautiful appearance.Two cases with subcutaneous liquid collection were found,which were delayed healing after repeated rinse.One case with subcutaneous infection prolonged unhealed,which healed through secondary repair under removing titanium mesh after six months.One case with titanium mesh exposing were repaired with near the scalp graft.Conclusions:The effects of three-dimensional CT reconstruction and titanium mesh digital computer on treatment of skull defects are good,which have extensive clinical prospect.
Objective:To investigate the clinical value of three-dimensional CT reconstruction and titanium mesh digital computer in repairing skull defects.Methods:Sixty-eight cases with skull defect were treated with titanium mesh through CT 3D reconstruction.Results:Sixty-four cases healed with beautiful appearance.Two cases with subcutaneous liquid collection were found,which were delayed healing after repeated rinse.One case with subcutaneous infection prolonged unhealed,which healed through secondary repair under removing titanium mesh after six months.One case with titanium mesh exposing were repaired with near the scalp graft.Conclusions:The effects of three-dimensional CT reconstruction and titanium mesh digital computer on treatment of skull defects are good,which have extensive clinical prospect.
2013, 37(2): 162-163.
Abstract:
Objective:To compare the effects and adverse reactions of flurbiprofen axetil combined with fentanyl in radical mastectomy for breast cancer postoperative intravenous analgesia.Methods:Sixty cases of breast cancer patients after operation treated with patient-controlled intravenous analgesia(PCIA) were randomly divided into two groups,30 cases in each group,group Ⅰ,postoperative analgesia with fentanyl was given fentanyl 1.0 mg and ondansetron hydrochloride injection in 8 mg and normal saline 100 ml;group Ⅱwas given lurbiprofen axetil 50 mg before skin suture,postoperative analgesia was given fentanyl 0.5 mg and lurbiprofen axetil 250 mg and ondansetron injection 8 mg and normal saline 100 ml.Two groups of PCIA pump set the same:maintenance dose of 2 ml/h,a single dose of 0.5 ml,locking time 15 min.Analgesia,sedation scores and the incidence of adverse reactions of two groups were observed in 12,24,48 hour.Results:Except for groupⅡ less than group Ⅰ(0.05);group Ⅱadverse reaction rate(20.0%) was lower than in group Ⅰ(46.7%)(P0.05).Conclusions:The effect of flurbiprofen axetil combined with fentanyl in radical mastectomy for breast cancer postoperative intravenous analgesia with fentanyl is similar,but adverse reaction is significantly reduced.
Objective:To compare the effects and adverse reactions of flurbiprofen axetil combined with fentanyl in radical mastectomy for breast cancer postoperative intravenous analgesia.Methods:Sixty cases of breast cancer patients after operation treated with patient-controlled intravenous analgesia(PCIA) were randomly divided into two groups,30 cases in each group,group Ⅰ,postoperative analgesia with fentanyl was given fentanyl 1.0 mg and ondansetron hydrochloride injection in 8 mg and normal saline 100 ml;group Ⅱwas given lurbiprofen axetil 50 mg before skin suture,postoperative analgesia was given fentanyl 0.5 mg and lurbiprofen axetil 250 mg and ondansetron injection 8 mg and normal saline 100 ml.Two groups of PCIA pump set the same:maintenance dose of 2 ml/h,a single dose of 0.5 ml,locking time 15 min.Analgesia,sedation scores and the incidence of adverse reactions of two groups were observed in 12,24,48 hour.Results:Except for groupⅡ less than group Ⅰ(0.05);group Ⅱadverse reaction rate(20.0%) was lower than in group Ⅰ(46.7%)(P0.05).Conclusions:The effect of flurbiprofen axetil combined with fentanyl in radical mastectomy for breast cancer postoperative intravenous analgesia with fentanyl is similar,but adverse reaction is significantly reduced.
2013, 37(2): 164-166.
Abstract:
Objective:To investigate the clinical effects of vacuum sealing drainage(VSD) technology on the repair of soft tissue defect of the limbs.Methods:Ten cases with soft tissue defects,which included 3 cases with tibial fractures with bone exposed,4 cases with large area infection of skin exfoliation and 3 cases with chronic ulcer were treated with VSD.Results:Through the VSD therapy,10 cases with good granulation tissue growth,fresh wound,good blood supply and dense granulation tissue were found,and which were treated with the phase 2 of skin grafts or flap transfer repair and received good clinical effects.Conclusions:VSD technology can improve the blood circulation of wound,reduce wound edema and inhibit bacterial growth to promote the growth of wound granulation tissue,which can provide the preparation of operation again.
Objective:To investigate the clinical effects of vacuum sealing drainage(VSD) technology on the repair of soft tissue defect of the limbs.Methods:Ten cases with soft tissue defects,which included 3 cases with tibial fractures with bone exposed,4 cases with large area infection of skin exfoliation and 3 cases with chronic ulcer were treated with VSD.Results:Through the VSD therapy,10 cases with good granulation tissue growth,fresh wound,good blood supply and dense granulation tissue were found,and which were treated with the phase 2 of skin grafts or flap transfer repair and received good clinical effects.Conclusions:VSD technology can improve the blood circulation of wound,reduce wound edema and inhibit bacterial growth to promote the growth of wound granulation tissue,which can provide the preparation of operation again.
2013, 37(2): 166-167.
Abstract:
Objective:To study the clinical and imaging features of influenza B in women in pregnancy so as to provide basis for the diagnosis,treatment,assessment and prognosis of the disease.Methods:The clinical features,treatment and imaging changes of 6 pregnant women with influenza B were analyzed retrospectively.Results:All the 6 cases presented the symptoms of fever and cough,but lung signs were unobvious.Three cases showed pneumonia signs and 3 bronchial infection signs on the chest imaging.Five cases receiving cesarean section had five healthy newborns.No respiratory failure occurred,and all the 6 cases were cured.The average hospital stay of the 5 cases with cesarean section was 6.6 days.Conclusions:The symptoms of influenza B in pregnant women are often severe,but presenting light physical signs.The imaging manifests small area virus pneumonia or bronchial infection signs;the prognosis is fairly good.Women in late pregnancy with influenza B should be ready to receive cesarean section at any time if necessary.
Objective:To study the clinical and imaging features of influenza B in women in pregnancy so as to provide basis for the diagnosis,treatment,assessment and prognosis of the disease.Methods:The clinical features,treatment and imaging changes of 6 pregnant women with influenza B were analyzed retrospectively.Results:All the 6 cases presented the symptoms of fever and cough,but lung signs were unobvious.Three cases showed pneumonia signs and 3 bronchial infection signs on the chest imaging.Five cases receiving cesarean section had five healthy newborns.No respiratory failure occurred,and all the 6 cases were cured.The average hospital stay of the 5 cases with cesarean section was 6.6 days.Conclusions:The symptoms of influenza B in pregnant women are often severe,but presenting light physical signs.The imaging manifests small area virus pneumonia or bronchial infection signs;the prognosis is fairly good.Women in late pregnancy with influenza B should be ready to receive cesarean section at any time if necessary.
2013, 37(2): 168-169;172;169.
Abstract:
Objective:To explore the clinical characteristics of chronic obstructive pulmonary disease(COPD) with pulmonary interstial fibrosis(PIF).Methods:The data of clinical symptoms,radiographic features,high resolution computerized tomography(HRCT) of the chest,arterial blood gas analysis and lung function test of 20 cases with COPD and PIF were analyzed retrospectively,and compared with COPD patients.Results:Compared with COPD patients,the clinical features of the patients with COPD and PIF were lung Velcro rale,lung dispersion function decreased,chest X-ray showed diffuse pitting nodular shadows mainly for mesh shape honeycomb shadow(P0.01),and HRCT showed most frosted glass shape and mesh shape pitting shadow honeycomb lung(P0.01).Conclusions:The COPD and PIF damage the ventilation and diffusion function of pulmonary,which can lead to severe hypoxemia and affect prognosis.The HRCT of the chest can provide important evidence in clinical diagnosis.
Objective:To explore the clinical characteristics of chronic obstructive pulmonary disease(COPD) with pulmonary interstial fibrosis(PIF).Methods:The data of clinical symptoms,radiographic features,high resolution computerized tomography(HRCT) of the chest,arterial blood gas analysis and lung function test of 20 cases with COPD and PIF were analyzed retrospectively,and compared with COPD patients.Results:Compared with COPD patients,the clinical features of the patients with COPD and PIF were lung Velcro rale,lung dispersion function decreased,chest X-ray showed diffuse pitting nodular shadows mainly for mesh shape honeycomb shadow(P0.01),and HRCT showed most frosted glass shape and mesh shape pitting shadow honeycomb lung(P0.01).Conclusions:The COPD and PIF damage the ventilation and diffusion function of pulmonary,which can lead to severe hypoxemia and affect prognosis.The HRCT of the chest can provide important evidence in clinical diagnosis.
2013, 37(2): 170-172;169.
Abstract:
Objective:To investigate the correlation of bone density and blood lipids levels in diabetic patients and know the effects of blood lipids on bone density.Methods:Two hundred and thirty-one cases with type 2 diabetes were divided into two groups,which were subdivided into different blood lipid group according to the blood lipids levels.The correlation of bone density and blood lipids levels of different sexes were analysed.Results:The data of simple linear correlation demonstrated that the triglyceride levels in males were a positive correlativity with bone density(P0.01) and high density lipid in females were negative correlativity with bone density(P0.05-P0.01).Conclusions:High triglyceride in males and low high density lipid in postmenopausal females may have some protective effect on bone density.
Objective:To investigate the correlation of bone density and blood lipids levels in diabetic patients and know the effects of blood lipids on bone density.Methods:Two hundred and thirty-one cases with type 2 diabetes were divided into two groups,which were subdivided into different blood lipid group according to the blood lipids levels.The correlation of bone density and blood lipids levels of different sexes were analysed.Results:The data of simple linear correlation demonstrated that the triglyceride levels in males were a positive correlativity with bone density(P0.01) and high density lipid in females were negative correlativity with bone density(P0.05-P0.01).Conclusions:High triglyceride in males and low high density lipid in postmenopausal females may have some protective effect on bone density.
2013, 37(2): 173-174;177;174.
Abstract:
Objective:To assess the clinical value of endovascular therapy for Budd-Chiari syndrome(BCS).Methods:Forty-five cases with BCS were analyzed retrospectively.There were 10 cases treated only with balloon dilatation angioplasty,35 cases with balloon dilatation angioplasty and placement of stent.Results:Forty-four cases were treated successfully,and the symptoms were relieved.Among the 4 cases of recurrent superior vena cava obstruction,1 case was received second stent placement,and 3 cases were treated with thrombolytic therapy,and recurrent symptoms were relieved.Conclusions:Endovascular therapy for BCS is very effective and safe.
Objective:To assess the clinical value of endovascular therapy for Budd-Chiari syndrome(BCS).Methods:Forty-five cases with BCS were analyzed retrospectively.There were 10 cases treated only with balloon dilatation angioplasty,35 cases with balloon dilatation angioplasty and placement of stent.Results:Forty-four cases were treated successfully,and the symptoms were relieved.Among the 4 cases of recurrent superior vena cava obstruction,1 case was received second stent placement,and 3 cases were treated with thrombolytic therapy,and recurrent symptoms were relieved.Conclusions:Endovascular therapy for BCS is very effective and safe.
2013, 37(2): 175-177;174.
Abstract:
Objective:To study the correlation between 18fluorine deoxyglucose(18F-FDG) positron emission tomography/computerized tomography(PET/CT) scan and bronchoalveolar lavage fluid(BALF)in patients with thoracic sarcoidosis,and explore the mechanism of 18F-FDG uptake in sarcoidosis.Methods:Nineteen patients with thoracic sarcoidosis underwent 18F-FDG PET/CT scan and BALF.The CD4+/CD8+ T cell ratio and serum angiotensin converting enzyme(sACE),tumor necrosis factor-(TNF-) and soluble interleukin-2 receptor(sIL-2R) levels in bronchoalveolar lavage fluid were detected.18F-FDG PET/CT scan was semi-quantitatively analyzed by maximum standardized uptake value(SUVmax) and mean standardized uptake value(SUVmean).The correlation between SUVmax,SUVmean,CD4+/CD8+ T cell ratio,sACE,TNF- and sIL-2R levels was also analyzed.Results:SUVmax was significantly correlated to SUVmean(P0.01).SUVmax was significantly correlated to sACE(P0.01) and TNF-(P0.01),respectively;SUVmean was also significantly correlated to sACE(P0.01) and TNF-(P0.01),respectively.SUVmean was correlated to CD4+/CD8+ T cell ratio(P0.05).Conclusions:The 18F-FDG uptake capacity is high in high load of sarcoidosis granuloma;its ability to 18F-FDG uptake may be associated with T cell activation.SUVmean may be superior to SUVmax in determining the activity of sarcoidosis.
Objective:To study the correlation between 18fluorine deoxyglucose(18F-FDG) positron emission tomography/computerized tomography(PET/CT) scan and bronchoalveolar lavage fluid(BALF)in patients with thoracic sarcoidosis,and explore the mechanism of 18F-FDG uptake in sarcoidosis.Methods:Nineteen patients with thoracic sarcoidosis underwent 18F-FDG PET/CT scan and BALF.The CD4+/CD8+ T cell ratio and serum angiotensin converting enzyme(sACE),tumor necrosis factor-(TNF-) and soluble interleukin-2 receptor(sIL-2R) levels in bronchoalveolar lavage fluid were detected.18F-FDG PET/CT scan was semi-quantitatively analyzed by maximum standardized uptake value(SUVmax) and mean standardized uptake value(SUVmean).The correlation between SUVmax,SUVmean,CD4+/CD8+ T cell ratio,sACE,TNF- and sIL-2R levels was also analyzed.Results:SUVmax was significantly correlated to SUVmean(P0.01).SUVmax was significantly correlated to sACE(P0.01) and TNF-(P0.01),respectively;SUVmean was also significantly correlated to sACE(P0.01) and TNF-(P0.01),respectively.SUVmean was correlated to CD4+/CD8+ T cell ratio(P0.05).Conclusions:The 18F-FDG uptake capacity is high in high load of sarcoidosis granuloma;its ability to 18F-FDG uptake may be associated with T cell activation.SUVmean may be superior to SUVmax in determining the activity of sarcoidosis.
2013, 37(2): 178-179;182;179.
Abstract:
Objective : To explore the clinical characteristics，diagnosis, differential diagnosis and treatment of spontaneous esophageal rupture and improve the clinical diagnosis ability.Methods:The clinical data of 2 cases with spontaneous esophageal rupture were retrospectively analyzed and the literatures were reviewed. One case was surgical treatment within 24 hours, other ease was treated with lavaging, drainaging and anti-infection. Results:One case cured through repairing, other case worsened because of his family giving up treatment. Conclusions:Obtaining complete and accurate disease historyis the key to avoid misdiagnosis. The chest radiograph, chest puncture, esophageal angiography and distinctive chest drainage can help diagnosis.The early diagnosis and surgerical repair and unobstructed drainage is the key of treatment.
Objective : To explore the clinical characteristics，diagnosis, differential diagnosis and treatment of spontaneous esophageal rupture and improve the clinical diagnosis ability.Methods:The clinical data of 2 cases with spontaneous esophageal rupture were retrospectively analyzed and the literatures were reviewed. One case was surgical treatment within 24 hours, other ease was treated with lavaging, drainaging and anti-infection. Results:One case cured through repairing, other case worsened because of his family giving up treatment. Conclusions:Obtaining complete and accurate disease historyis the key to avoid misdiagnosis. The chest radiograph, chest puncture, esophageal angiography and distinctive chest drainage can help diagnosis.The early diagnosis and surgerical repair and unobstructed drainage is the key of treatment.
2013, 37(2): 180-182;179.
Abstract:
Objective:To study the clinical pathological characteristics,diagnosis,therapy and prognosis of ovarian immature teratomas(OIT) combined with gliomatosis peritonei(GP).Methods:The histomorphology and immunohistochemistry results of a case with OIT and GP was analyzed under light microscope,and related literatures were reviewed.Results:A huge cystic and solid mass in the abdomined cavity was showed in a 12-year-old girl patient by CT 23.0 cm12.0 cm10.0 cm tumor with intact capsule and adhesion in left accessory was found in the course of operation,which was composed of mature and immature tissues,mostly neurogliatissue derived from epidermal,mesodermal and endodermal elements under microscope.Many grey-white nodules with 0.1 to 0.3 cm in diameter located on the surface of the tumor,pelvic cavity and omentum,which were mature neurogliatissue with clear boundary and no infiltrating.Immunohistochemically,the staining of glial fibrillary acidic protein(GFAP),S-100 protein,vimentin showed positive in the mature glial tissue and cytokeratin staining was positive in the mesothelial cells.The mass tumor and a part of omentum were excised.There was no tumor recurrence and metastasis in the follow-up 26 months.Conclusions:OIT with GP is extremely rare,mature neurogliatissue metastases in omentum indicates that OIT may differentiate up to mature and the prognosis for OIT with GP is good.Surgery and/or chemotherapy are employed according to the stage and pathological differentiation of OIT.
Objective:To study the clinical pathological characteristics,diagnosis,therapy and prognosis of ovarian immature teratomas(OIT) combined with gliomatosis peritonei(GP).Methods:The histomorphology and immunohistochemistry results of a case with OIT and GP was analyzed under light microscope,and related literatures were reviewed.Results:A huge cystic and solid mass in the abdomined cavity was showed in a 12-year-old girl patient by CT 23.0 cm12.0 cm10.0 cm tumor with intact capsule and adhesion in left accessory was found in the course of operation,which was composed of mature and immature tissues,mostly neurogliatissue derived from epidermal,mesodermal and endodermal elements under microscope.Many grey-white nodules with 0.1 to 0.3 cm in diameter located on the surface of the tumor,pelvic cavity and omentum,which were mature neurogliatissue with clear boundary and no infiltrating.Immunohistochemically,the staining of glial fibrillary acidic protein(GFAP),S-100 protein,vimentin showed positive in the mature glial tissue and cytokeratin staining was positive in the mesothelial cells.The mass tumor and a part of omentum were excised.There was no tumor recurrence and metastasis in the follow-up 26 months.Conclusions:OIT with GP is extremely rare,mature neurogliatissue metastases in omentum indicates that OIT may differentiate up to mature and the prognosis for OIT with GP is good.Surgery and/or chemotherapy are employed according to the stage and pathological differentiation of OIT.
2013, 37(2): 192-195.
Abstract:
Objective:To investigate the value of color Doppler ultrasound in the diagnosis of triple negative breast cancer(TNBC).Methods:One hundred and sixty-nine cases of breast occupying lesions which were diagnosed by color Doppler ultrasound and confirmed as breast cancer by surgery and pathology were divided into TNBC groups(37 cases) and non-TNBC group(132 cases) according to the expression of estrogen receptor(ER),progesterone receptor(PR) and human epidermal growth factor receptor 2(HER2) determined by immunohistochemical staining.The ultrasonic image,pathological manifestation and clinical condition of the 2 groups were compared and analyzed.Results:Ultrasonic images showed that the TNBC group had a greater proportion in the masses with clear boundary and a smaller proportion in the masses with short burr on the edge than the non-TNBC group(P0.05);the TNBC group had lower echoes and less calcification than the non-TNBC group(P0.01),and its posterior sound shadow was less attenuated(P0.05);most of the masses in TNBC group showed no blood stream or little blood stream(P0.05);the proportion of flow resistance index0.7 in TNBC group was greater than that in non-TNBC group(P0.05).Pathological examinations showed that axillary lymph node metastases occurred more frequently in the TNBC group(P0.05).Conclusions:The above features make the mass more likely to be a benign one.The technique of color Doppler ultrasound is of use in the early diagnosis of TNBC.
Objective:To investigate the value of color Doppler ultrasound in the diagnosis of triple negative breast cancer(TNBC).Methods:One hundred and sixty-nine cases of breast occupying lesions which were diagnosed by color Doppler ultrasound and confirmed as breast cancer by surgery and pathology were divided into TNBC groups(37 cases) and non-TNBC group(132 cases) according to the expression of estrogen receptor(ER),progesterone receptor(PR) and human epidermal growth factor receptor 2(HER2) determined by immunohistochemical staining.The ultrasonic image,pathological manifestation and clinical condition of the 2 groups were compared and analyzed.Results:Ultrasonic images showed that the TNBC group had a greater proportion in the masses with clear boundary and a smaller proportion in the masses with short burr on the edge than the non-TNBC group(P0.05);the TNBC group had lower echoes and less calcification than the non-TNBC group(P0.01),and its posterior sound shadow was less attenuated(P0.05);most of the masses in TNBC group showed no blood stream or little blood stream(P0.05);the proportion of flow resistance index0.7 in TNBC group was greater than that in non-TNBC group(P0.05).Pathological examinations showed that axillary lymph node metastases occurred more frequently in the TNBC group(P0.05).Conclusions:The above features make the mass more likely to be a benign one.The technique of color Doppler ultrasound is of use in the early diagnosis of TNBC.
2013, 37(2): 196-199.
Abstract:
Objective:To explore the association of interpersonal relationship with family cohesion and adaptability among college students of nursing major.Methods:Two hundred and twenty-five nursing major freshmen and sophomores who scored no less than 9 on the interpersonal relationship scale were selected to fill out the social anxiety scale,the social avoidance and distress scale,and the family cohesion and adaptability scale.Results:No statistically significant differences were found across grades regarding interpersonal relationship,actual family cohesion,actual adaptability,ideal family cohesion and ideal adaptability(P0.05).However,there were significant gender differences in interpersonal relationship(P0.01).Interpersonal relationship was positively correlated with social anxiety,social avoidance,social distress,and the overall social avoidance and distress score(P0.01).Interpersonal relationship was negatively correlated with ideal family adaptability(P0.01).The scores on actual family cohesion and actual adaptability were lower than the norm(P0.01),and the scores in ideal family cohesion,ideal adaptability,the degree of dissatisfaction with cohesion(the difference between ideal and actual cohesion scores),the degree of dissatisfaction with adaptability(the difference between ideal and actual adaptability scores) were all higher than the norm(P0.01).Conclusions:The nursing major college students who have problems with interpersonal relationship show relatively low level of family cohesion and adaptability.Male students have more problems than the female,and those who have more problems show lower level of ideal family adaptability.Therefore,it is necessary to offer adequate family intervention to those who have difficulties in interpersonal relationship.
Objective:To explore the association of interpersonal relationship with family cohesion and adaptability among college students of nursing major.Methods:Two hundred and twenty-five nursing major freshmen and sophomores who scored no less than 9 on the interpersonal relationship scale were selected to fill out the social anxiety scale,the social avoidance and distress scale,and the family cohesion and adaptability scale.Results:No statistically significant differences were found across grades regarding interpersonal relationship,actual family cohesion,actual adaptability,ideal family cohesion and ideal adaptability(P0.05).However,there were significant gender differences in interpersonal relationship(P0.01).Interpersonal relationship was positively correlated with social anxiety,social avoidance,social distress,and the overall social avoidance and distress score(P0.01).Interpersonal relationship was negatively correlated with ideal family adaptability(P0.01).The scores on actual family cohesion and actual adaptability were lower than the norm(P0.01),and the scores in ideal family cohesion,ideal adaptability,the degree of dissatisfaction with cohesion(the difference between ideal and actual cohesion scores),the degree of dissatisfaction with adaptability(the difference between ideal and actual adaptability scores) were all higher than the norm(P0.01).Conclusions:The nursing major college students who have problems with interpersonal relationship show relatively low level of family cohesion and adaptability.Male students have more problems than the female,and those who have more problems show lower level of ideal family adaptability.Therefore,it is necessary to offer adequate family intervention to those who have difficulties in interpersonal relationship.
2013, 37(2): 200-202.
Abstract:
Objective:To understand the personality and behavior traits in patients with epileptic psychiatric disorders.Methods:Thirty-eight patients with epileptic psychiatric disorders(observation group)and 39 healthy adults(control group) were investigated by Irrational Beliefs Scale,the Cattells Sixteen Personality Factor Questionnaire(16PF),the Barret Impulsiveness Scale and Buss-Perry Attack Scale.Results:The Irrational Beliefs Scale showed that the observation group had higher scores than the control in low frustration tolerance,generalization comments,absolute requirements and the total score(P0.01).In 16PF,the observation group had lower scores than the control in gregarious nature,intelligence,stability and excitability(P0.05 to P0.01),and higher scores in tension,sensitivity,fantasy,sophisticated and suspicion(P0.05 to P0.01),the other scores were not significantly different(P0.05).The Barret Impulsiveness Scale displayed that the observation group had higher scores than the control in plan,action,cognitive and the total score(P0.01);the Buss-Perry Attack Scale demonstrated that the observation group had higher scores than the control in anger,hostility,physical aggression,language offensive,self-attack and the total score(P0.01).Conclusions:The patients with epileptic psychiatric disorders often had irrational beliefs and behavior traits,possessing the personality trait of low intelligence,instability,suspicion,sensitivity,fantasy and non-self-discipline,comprehensive intervention therapy is necessary for psychiatric patients with epilepsy.
Objective:To understand the personality and behavior traits in patients with epileptic psychiatric disorders.Methods:Thirty-eight patients with epileptic psychiatric disorders(observation group)and 39 healthy adults(control group) were investigated by Irrational Beliefs Scale,the Cattells Sixteen Personality Factor Questionnaire(16PF),the Barret Impulsiveness Scale and Buss-Perry Attack Scale.Results:The Irrational Beliefs Scale showed that the observation group had higher scores than the control in low frustration tolerance,generalization comments,absolute requirements and the total score(P0.01).In 16PF,the observation group had lower scores than the control in gregarious nature,intelligence,stability and excitability(P0.05 to P0.01),and higher scores in tension,sensitivity,fantasy,sophisticated and suspicion(P0.05 to P0.01),the other scores were not significantly different(P0.05).The Barret Impulsiveness Scale displayed that the observation group had higher scores than the control in plan,action,cognitive and the total score(P0.01);the Buss-Perry Attack Scale demonstrated that the observation group had higher scores than the control in anger,hostility,physical aggression,language offensive,self-attack and the total score(P0.01).Conclusions:The patients with epileptic psychiatric disorders often had irrational beliefs and behavior traits,possessing the personality trait of low intelligence,instability,suspicion,sensitivity,fantasy and non-self-discipline,comprehensive intervention therapy is necessary for psychiatric patients with epilepsy.
2013, 37(2): 203-205.
Abstract:
Objective:To investigate the distribution and antibiotic resistance of pathogens isolated from nosocomial lower respiratory tract infection for rational antimicrobial therapy.Methods:Kirby-Bauer method was used to test the drug susceptibility of clinical isolated pathogenic bacteria from 3 024 patients sputum.The data were analyzed by WHO NET 5.4 software.Results:In 3 024 clinical isolated pathogenic bacteria,the top five pathogens were P.aeruginosa,K.pneumoniae,A.baumanii,S.aureus and E.coli.The overall drug resistance rate of P.aeruginosa was low,A.baumanii was multi-drug resistant pathogen,the resistance rate of enterobacteriace to antibiotics was increased in recent years except imipenem and meropenem,the rate of methicillin resistant S.aureus was high in S.aureus,and was shown multiple resistance to antibiotics.Conclusions:Gram-negative bacilli are the major pathogens in nosocomial lower respiratory tract infection,antibiotic resistance becomes more prevalent in some major pathogens.
Objective:To investigate the distribution and antibiotic resistance of pathogens isolated from nosocomial lower respiratory tract infection for rational antimicrobial therapy.Methods:Kirby-Bauer method was used to test the drug susceptibility of clinical isolated pathogenic bacteria from 3 024 patients sputum.The data were analyzed by WHO NET 5.4 software.Results:In 3 024 clinical isolated pathogenic bacteria,the top five pathogens were P.aeruginosa,K.pneumoniae,A.baumanii,S.aureus and E.coli.The overall drug resistance rate of P.aeruginosa was low,A.baumanii was multi-drug resistant pathogen,the resistance rate of enterobacteriace to antibiotics was increased in recent years except imipenem and meropenem,the rate of methicillin resistant S.aureus was high in S.aureus,and was shown multiple resistance to antibiotics.Conclusions:Gram-negative bacilli are the major pathogens in nosocomial lower respiratory tract infection,antibiotic resistance becomes more prevalent in some major pathogens.
2013, 37(2): 206-207.
Abstract:
Objective:To explore the relationship between chromosomal polymorphism and adverse pregnancy.Methods:Blood lymphocyte isolated from 1 086 patients which had the history of adverse pregnancy were cultured,G banding was stained and the chromosome karyotype was analyzed.Results:One hundred and ninety-eight cases of abnormal karyotype were detected,accounting for 18.23% in all subjects.There were 59 cases of chromosomal polymorphism,accounting for 19.8% in chromosome abnormalities.Among them,there were 27 cases of secondary constriction increased,9 cases of inversion of chromosome 9,7 cases of D/G set with body variant and 16 cases of Y chromosome variation.Conclusions:There is significant relationship between chromosomal polymorphism and adverse pregnancy.The clinical effects can not be ignored.
Objective:To explore the relationship between chromosomal polymorphism and adverse pregnancy.Methods:Blood lymphocyte isolated from 1 086 patients which had the history of adverse pregnancy were cultured,G banding was stained and the chromosome karyotype was analyzed.Results:One hundred and ninety-eight cases of abnormal karyotype were detected,accounting for 18.23% in all subjects.There were 59 cases of chromosomal polymorphism,accounting for 19.8% in chromosome abnormalities.Among them,there were 27 cases of secondary constriction increased,9 cases of inversion of chromosome 9,7 cases of D/G set with body variant and 16 cases of Y chromosome variation.Conclusions:There is significant relationship between chromosomal polymorphism and adverse pregnancy.The clinical effects can not be ignored.
2013, 37(2): 208-209.
Abstract:
Objective:To evaluate the clinical application of the UF-500i Flow Cytometer in screening the asymptomatic urinary infection of pregnant women.Methods:The leukocytes and bacteria in 500 mid-stream urine specimens of pregnant women were detected and compared with UF-500i.Results:The positive rates of UF-500i and urine culture were 10.4% and 7.6% respectively,and their differences had no statistical significance and kept considerable consistency(Kappa=0.999,P》0.05).The sensitivity and specificity of the UF-500i detection for urinary infection were 88.4% and 96.9% and the positive and negative predictive value were 73.1% and 98.9% respectively.Conclusions:The UF-500i Flow Cytometer in screening the asymptomatic urinary infection of pregnant women is rapidly,convenient and economical,which has good application value,and the urine contamination must be pay attention to.
Objective:To evaluate the clinical application of the UF-500i Flow Cytometer in screening the asymptomatic urinary infection of pregnant women.Methods:The leukocytes and bacteria in 500 mid-stream urine specimens of pregnant women were detected and compared with UF-500i.Results:The positive rates of UF-500i and urine culture were 10.4% and 7.6% respectively,and their differences had no statistical significance and kept considerable consistency(Kappa=0.999,P》0.05).The sensitivity and specificity of the UF-500i detection for urinary infection were 88.4% and 96.9% and the positive and negative predictive value were 73.1% and 98.9% respectively.Conclusions:The UF-500i Flow Cytometer in screening the asymptomatic urinary infection of pregnant women is rapidly,convenient and economical,which has good application value,and the urine contamination must be pay attention to.
2013, 37(2): 210-211.
Abstract:
Objective:To investigate the application value of serum cystatin C(Cys C) levels in the diagnosis of diabetic sligt kidney damage.Methods:The concentrations of serum Cys C and creatinine(Cr) in 80 cases with type 2 diabete(observation group)and in 35 healthy adults(control group) were detected through turbidimetric method by Bayer ADVIA1800 automatic biochemical analyzer.The diagnostic sensitivity of Cys C and Cr of diabetic sligt kidney damage were analyzed.Results:The levels of Cys C in observation and control group had significant difference(P0.01),but for Cr had no(P0.05).Conclusions:Serum Cys C is sensitive index in the diagnosis of early diabetic kidney damage,which has certain advantages than Cr.
Objective:To investigate the application value of serum cystatin C(Cys C) levels in the diagnosis of diabetic sligt kidney damage.Methods:The concentrations of serum Cys C and creatinine(Cr) in 80 cases with type 2 diabete(observation group)and in 35 healthy adults(control group) were detected through turbidimetric method by Bayer ADVIA1800 automatic biochemical analyzer.The diagnostic sensitivity of Cys C and Cr of diabetic sligt kidney damage were analyzed.Results:The levels of Cys C in observation and control group had significant difference(P0.01),but for Cr had no(P0.05).Conclusions:Serum Cys C is sensitive index in the diagnosis of early diabetic kidney damage,which has certain advantages than Cr.
2013, 37(2): 212-214.
Abstract:
Objective:To promote graduate studentsprofessional English teaching mode reform and change the traditional language base-targeted and fundamental skill-oriented teaching mode,a new mode tailored to the needs of graduate students medical English learning in new era should be explored,which may help the students to apply their English listening,speaking,reading,writing and translation ability to professional study and research.Methods:This paper discusses the main problems existing in graduate students medical English teaching,pinpoints the theoretical as well as practical merits of peer response and proposes suggestions on how to practice it in class.Results:The performance of peer response in medical English Abstract writing class significantly elevates the students initiativeness,reinforces their team spirit and cultivates their critical and independent thinking.Conclusions:Peer response is an effective method in graduate students medical English teaching,which is of rich theoretical and practical significance in the reform of teaching method.
Objective:To promote graduate studentsprofessional English teaching mode reform and change the traditional language base-targeted and fundamental skill-oriented teaching mode,a new mode tailored to the needs of graduate students medical English learning in new era should be explored,which may help the students to apply their English listening,speaking,reading,writing and translation ability to professional study and research.Methods:This paper discusses the main problems existing in graduate students medical English teaching,pinpoints the theoretical as well as practical merits of peer response and proposes suggestions on how to practice it in class.Results:The performance of peer response in medical English Abstract writing class significantly elevates the students initiativeness,reinforces their team spirit and cultivates their critical and independent thinking.Conclusions:Peer response is an effective method in graduate students medical English teaching,which is of rich theoretical and practical significance in the reform of teaching method.
2013, 37(2): 216-218.
Abstract:
Objective:To investigate the effects of the scene teaching method in nursing skill teaching for trauma emergency.Methods:One hundred and twenty full-time junior college nursing trainees were divided into the experimental group and the control group(60 students each group) by tossing the coin.The experimental and control group were taught by the scene teaching and traditional teaching method respectively.Results:The average scores of the knowledge,practicing skill and clinical practice ability of the experimental group were higher than that of the control group(P0.01).The satisfaction degree of the experimental group was 97.4%.Conclusions:The scene teaching method in nursing skill teaching of trauma emergency is in favour of promoving the effects of clinic teaching and the nursing students comprehensive quality.
Objective:To investigate the effects of the scene teaching method in nursing skill teaching for trauma emergency.Methods:One hundred and twenty full-time junior college nursing trainees were divided into the experimental group and the control group(60 students each group) by tossing the coin.The experimental and control group were taught by the scene teaching and traditional teaching method respectively.Results:The average scores of the knowledge,practicing skill and clinical practice ability of the experimental group were higher than that of the control group(P0.01).The satisfaction degree of the experimental group was 97.4%.Conclusions:The scene teaching method in nursing skill teaching of trauma emergency is in favour of promoving the effects of clinic teaching and the nursing students comprehensive quality.
2013, 37(2): 221-224.
Abstract:
Objective:To explore the effect of admission education way on anxiety depression and satisfaction of intensive care unit(ICU) patients spouses.Methods:Sixty patients spouses who came from ICU(from October 2010 to December 2010) were as control group,common practice admission education way was adopted.Another 60 patients spouses who came from ICU(from January 2011 to March 2011) were as experimental group,associative admission education way was adopted.Within 24 hour and after 72 hour,the same questionnaire(self-rating anxiety scale and self-rating depression scale of Zung) was used,and after 72 hour,the questionnaire to investigate satisfaction was used,the results in two groups were compared.Results:Before taking admission education,both the anxiety depression score and the incidence of anxiety depression in the two groups were not statistically significant(P0.05),but both higher than national standard(P0.01).After taking admission education,the anxiety depression score and the incidence of depression in experimental group was lower than those in control group(P0.01),but the degree of satisfaction was higher than that in control group(P0.01).Conclusions:Associative admission education may reduce anxiety depression and reduce the incidence of depression,moreover increase the degree of satisfaction of ICU patients spouses.
Objective:To explore the effect of admission education way on anxiety depression and satisfaction of intensive care unit(ICU) patients spouses.Methods:Sixty patients spouses who came from ICU(from October 2010 to December 2010) were as control group,common practice admission education way was adopted.Another 60 patients spouses who came from ICU(from January 2011 to March 2011) were as experimental group,associative admission education way was adopted.Within 24 hour and after 72 hour,the same questionnaire(self-rating anxiety scale and self-rating depression scale of Zung) was used,and after 72 hour,the questionnaire to investigate satisfaction was used,the results in two groups were compared.Results:Before taking admission education,both the anxiety depression score and the incidence of anxiety depression in the two groups were not statistically significant(P0.05),but both higher than national standard(P0.01).After taking admission education,the anxiety depression score and the incidence of depression in experimental group was lower than those in control group(P0.01),but the degree of satisfaction was higher than that in control group(P0.01).Conclusions:Associative admission education may reduce anxiety depression and reduce the incidence of depression,moreover increase the degree of satisfaction of ICU patients spouses.
2013, 37(2): 224-226.
Abstract:
Objective:To explore the different routes of supplement kalium and nursing intervention for patients with kaliopenia.Methods:Thirty cases with kaliopenia were supplemented with kalium by oral,vein and ultrasonic aerosol inhalation routes.Six cases were supplemented with 10% potassium chloride or potassium citrate by oral intaking.Sixteen cases were supplemented with kalium by intravenous infusion,the concentration and velocity of supplement kalium were controlled and the occurrence of phlebitis was observed.Five cases were supplemented with high concentration kalium by intravenous infusion,the vital signs of patients were monitored closely.Three cases were supplemented with kalium by ultrasonic aerosol inhalation.Good food and mental nursing and health education for patients were performed.Results:The concentrations of potassium in serum of all patients raised to the normal levels after 24 hours.There were not complications including arrhythmia for all patients.Conclusions:The effects of supplement kalium by 3 routes are effective,but close monitoring,good nursing and preventing complications should be noticed during the process of supplement kalium.
Objective:To explore the different routes of supplement kalium and nursing intervention for patients with kaliopenia.Methods:Thirty cases with kaliopenia were supplemented with kalium by oral,vein and ultrasonic aerosol inhalation routes.Six cases were supplemented with 10% potassium chloride or potassium citrate by oral intaking.Sixteen cases were supplemented with kalium by intravenous infusion,the concentration and velocity of supplement kalium were controlled and the occurrence of phlebitis was observed.Five cases were supplemented with high concentration kalium by intravenous infusion,the vital signs of patients were monitored closely.Three cases were supplemented with kalium by ultrasonic aerosol inhalation.Good food and mental nursing and health education for patients were performed.Results:The concentrations of potassium in serum of all patients raised to the normal levels after 24 hours.There were not complications including arrhythmia for all patients.Conclusions:The effects of supplement kalium by 3 routes are effective,but close monitoring,good nursing and preventing complications should be noticed during the process of supplement kalium.
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