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2013 Vol. 38, No. 3
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2013, 37(3): 249-253.
Abstract:
Objective：To investigate the molecular mechanism of arsenic trioxide (As2O3)inhibiting telomerase human telomerasereverse transcriptase(hTERT) expression in HL-60 cells. Methods：The different fragments of hTERT promoter luoiferase geneexpression vector were construc;ted and transfected into HL-60 cells with or without As2O3. The changes of luoiferase activity whichindirectly rellected the role of As2O3 on hTERT promoter different fragments were detected. Results：The luoiferase activities in differentfragments of hTERT promoter gene expression vector were decreased with As2O3(P0.05toP0.01)Conclusions：As2O3 can inhibit telomerase activity of hTERT promoter in HL-60 cells
Objective：To investigate the molecular mechanism of arsenic trioxide (As2O3)inhibiting telomerase human telomerasereverse transcriptase(hTERT) expression in HL-60 cells. Methods：The different fragments of hTERT promoter luoiferase geneexpression vector were construc;ted and transfected into HL-60 cells with or without As2O3. The changes of luoiferase activity whichindirectly rellected the role of As2O3 on hTERT promoter different fragments were detected. Results：The luoiferase activities in differentfragments of hTERT promoter gene expression vector were decreased with As2O3(P0.05toP0.01)Conclusions：As2O3 can inhibit telomerase activity of hTERT promoter in HL-60 cells
2013, 37(3): 253-257.
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2013, 37(3): 258-262.
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Objective:To study the expression and clinical significance of eIF4E and CyclinD1 in endometrial hyperplasia and endometrial carcinoma.Methods:The expressions of eIF4E and CyclinD1 in 40 cases of simple hyperplasia,40 cases of complex hyperplasia(25 cases of atypical hyperplasia),65 cases of endometrial carcinoma and 15 cases of normal proliferative endometrium were detected by means of immunohistochemical EliVision,the related pathological parameters were analyzed.Results:The positive expression of eIF4E in normal proliferative endometrium,simple endometrial hyperplasia,complex endometrial hyperplasia,atypical hyperplasia and endometriod adenocarcinoma was 53.33%,72.50%,80.00%,84.00% and 90.77%,respectively;while the positive expression of CyclinD1 was 6.67%,52.50%,70.33%,80.00% and 81.54%,respectively.The expression of eIF4E was only significantly different between the endometrial carcinoma and the normal proliferative endometrium(P0.01);the expression of CyclinD1 in endometriod adenocarcinoma,atypical hyperplasia and complex endometrial hyperplasia was significantly different from that in normal proliferative endometrium.The positive expression of eIF4E and CyclinD1 in endometriod adenocarcinoma was not obviously related to the TNM stage,pathological grade or lymph node metastasis(P0.05).Statistical analysis showed that there was a positive correlation between eIF4E and CyclinD1 expression in endometriod adenocarcinoma(P0.05).Conclusions:EIF4E and CyclinD1 are both over-expressed in endometrial carcinoma,and the synergy of them may contribute to the development of endometrial carcinoma.
Objective:To study the expression and clinical significance of eIF4E and CyclinD1 in endometrial hyperplasia and endometrial carcinoma.Methods:The expressions of eIF4E and CyclinD1 in 40 cases of simple hyperplasia,40 cases of complex hyperplasia(25 cases of atypical hyperplasia),65 cases of endometrial carcinoma and 15 cases of normal proliferative endometrium were detected by means of immunohistochemical EliVision,the related pathological parameters were analyzed.Results:The positive expression of eIF4E in normal proliferative endometrium,simple endometrial hyperplasia,complex endometrial hyperplasia,atypical hyperplasia and endometriod adenocarcinoma was 53.33%,72.50%,80.00%,84.00% and 90.77%,respectively;while the positive expression of CyclinD1 was 6.67%,52.50%,70.33%,80.00% and 81.54%,respectively.The expression of eIF4E was only significantly different between the endometrial carcinoma and the normal proliferative endometrium(P0.01);the expression of CyclinD1 in endometriod adenocarcinoma,atypical hyperplasia and complex endometrial hyperplasia was significantly different from that in normal proliferative endometrium.The positive expression of eIF4E and CyclinD1 in endometriod adenocarcinoma was not obviously related to the TNM stage,pathological grade or lymph node metastasis(P0.05).Statistical analysis showed that there was a positive correlation between eIF4E and CyclinD1 expression in endometriod adenocarcinoma(P0.05).Conclusions:EIF4E and CyclinD1 are both over-expressed in endometrial carcinoma,and the synergy of them may contribute to the development of endometrial carcinoma.
2013, 37(3): 262-263,267.
Abstract:
Objective:To observe the protective effect of jinkuihugan decoction on CCl4-induced acute liver injury in mice.Methods:Acute CCl4-induced liver injury model in mice was established.The experimental animals were randomly divided into normal control group,model group,the positive control group(bifendatatum),jinkuihugan decoction at low,medium and high dose groups according to the body weight.The levels of serum alanine aminotransferase(ALT),aspartate aminotransferase(AST),and malondialdehyde(MDA) content,superoxide dismutase(SOD) in liver,were determined.Results:The levels of serum ALT and AST of jinkuihugan decoction content at medium and high dose groups were significantly lower than in model group(P0.01),MDA content was significantly lower than in model group and SOD content was significantly higher than in model group(P0.05-P0.01).Conclusions:Jinkuibugan decoction has the protective effect on CCl4-induced acute liver injury in mice.
Objective:To observe the protective effect of jinkuihugan decoction on CCl4-induced acute liver injury in mice.Methods:Acute CCl4-induced liver injury model in mice was established.The experimental animals were randomly divided into normal control group,model group,the positive control group(bifendatatum),jinkuihugan decoction at low,medium and high dose groups according to the body weight.The levels of serum alanine aminotransferase(ALT),aspartate aminotransferase(AST),and malondialdehyde(MDA) content,superoxide dismutase(SOD) in liver,were determined.Results:The levels of serum ALT and AST of jinkuihugan decoction content at medium and high dose groups were significantly lower than in model group(P0.01),MDA content was significantly lower than in model group and SOD content was significantly higher than in model group(P0.05-P0.01).Conclusions:Jinkuibugan decoction has the protective effect on CCl4-induced acute liver injury in mice.
2013, 37(3): 264-267.
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Objective:To investigate the effects of signal transduction and activators of transcription 3(STAT3) antisense oligonucleotide on proliferation and apoptosis in human cervical carcinoma HeLa cell in vitro.Methods:The cell lines were divided into three groups,blank control group,sense oligonucleotide group,and antisense oligonucleotide group.The antisense oligonucleotide was designed based on STAT3 gene sequence and transfected into HeLa cells with Lipofectamine 2000.STAT3 mRNA and protein levels were detected by RT-PCR and western blot respectively.The cell proliferation was measured by MTT,the early apoptosis was analyzed by flow cytometry.Results:In contrast to the blank control group and sense oligonucleotide group,STAT3 mRNA and protein levels in antisense oligonucleotide group were down regulated(P0.05),the proliferation was inhibited and early apoptosis was increased(P0.05 and P0.01).Conclusions:The STAT3 antisense oligonucleotide can inhibit proliferation and induce apoptosis by down-regulated the expression of STAT3 in HeLa cells.It may be a new kind of treatment method for cervical carcinoma.
Objective:To investigate the effects of signal transduction and activators of transcription 3(STAT3) antisense oligonucleotide on proliferation and apoptosis in human cervical carcinoma HeLa cell in vitro.Methods:The cell lines were divided into three groups,blank control group,sense oligonucleotide group,and antisense oligonucleotide group.The antisense oligonucleotide was designed based on STAT3 gene sequence and transfected into HeLa cells with Lipofectamine 2000.STAT3 mRNA and protein levels were detected by RT-PCR and western blot respectively.The cell proliferation was measured by MTT,the early apoptosis was analyzed by flow cytometry.Results:In contrast to the blank control group and sense oligonucleotide group,STAT3 mRNA and protein levels in antisense oligonucleotide group were down regulated(P0.05),the proliferation was inhibited and early apoptosis was increased(P0.05 and P0.01).Conclusions:The STAT3 antisense oligonucleotide can inhibit proliferation and induce apoptosis by down-regulated the expression of STAT3 in HeLa cells.It may be a new kind of treatment method for cervical carcinoma.
2013, 37(3): 268-269,272.
Abstract:
Objective:To explore the value of liver fibrosis serum markers and liver function in the patients with liver cirrhosis.Methods:Twenty-three patients with liver cirrhosis in the resting stage and 23 patients with liver cirrhosis in the active stage were investigated.The hyaluronic acid(HA),laminin(LN),procollagen Ⅲ N-terminal peptide(PⅢNP) and collagen type Ⅳ(CⅣ) of liver fibrosis serum markers of all cases were determined by Chemiluminescence method and the levels of alanine aminotransferase(ALT) and aspartate aminotransferase(AST) were detected.Results:The levels of serum HA and LN of the cases with liver cirrhosis in the active stage were markedly higher than that of the cases with liver cirrhosis in the resting stage(P0.05),while the serum levels of PⅢNP and CⅣ of two groups had no significant difference(P0.05).Between the levels of HA,LN,PⅢNP and CⅣ and ALT and AST existed the positive correlation(P0.01 to P0.05).Conclusions:The serum levels of HA,LN,PⅢNP and CⅣ can reflect the degree of liver fibrosis,which change is very important.The serological indexes of liver fibrosis in the liver cirrhosis in the resting stage is obviously lower than that in the active stage.The detection of the serological indexes of hepatic fibrosis combined with liver function can help to monitor the evolution of the disease and treatment.
Objective:To explore the value of liver fibrosis serum markers and liver function in the patients with liver cirrhosis.Methods:Twenty-three patients with liver cirrhosis in the resting stage and 23 patients with liver cirrhosis in the active stage were investigated.The hyaluronic acid(HA),laminin(LN),procollagen Ⅲ N-terminal peptide(PⅢNP) and collagen type Ⅳ(CⅣ) of liver fibrosis serum markers of all cases were determined by Chemiluminescence method and the levels of alanine aminotransferase(ALT) and aspartate aminotransferase(AST) were detected.Results:The levels of serum HA and LN of the cases with liver cirrhosis in the active stage were markedly higher than that of the cases with liver cirrhosis in the resting stage(P0.05),while the serum levels of PⅢNP and CⅣ of two groups had no significant difference(P0.05).Between the levels of HA,LN,PⅢNP and CⅣ and ALT and AST existed the positive correlation(P0.01 to P0.05).Conclusions:The serum levels of HA,LN,PⅢNP and CⅣ can reflect the degree of liver fibrosis,which change is very important.The serological indexes of liver fibrosis in the liver cirrhosis in the resting stage is obviously lower than that in the active stage.The detection of the serological indexes of hepatic fibrosis combined with liver function can help to monitor the evolution of the disease and treatment.
2013, 37(3): 270-272.
Abstract:
Objective:To investigate the expressions of nuclear factor-B(NF-B),matrix metalloproteinase-9(MMP-9) and cyclooxygenase-2(COX-2) in osteosarcoma and analyze their relationship in angiogenesis.Methods:The expressions of NF-B,MMP-9 and COX-2 proteins in 52 specimens with osteosarcoma were determined by S-P immunohistochemical staining method,and 40 specimens of osteochondroma were served as control.Microvessel density were calculated with anti-CD34 monoclonal antibody stainning.Results:The positive expressions of NF-B,MMP-9 and COX-2 in osteosarcoma were significantly higher than those in osteochondroma(P0.05),there were positive correlations between the expressions of NF-B and MMP-9,NF-B and COX-2,and the close correlations were found between NF-B,MMP-9,NF-B and microvessel density.Conclusions:The expressions of NF-B,MMP-9 and COX-2 in osteosarcoma are all high.The three indexes may promote angiogenesis of osteosarcoma.
Objective:To investigate the expressions of nuclear factor-B(NF-B),matrix metalloproteinase-9(MMP-9) and cyclooxygenase-2(COX-2) in osteosarcoma and analyze their relationship in angiogenesis.Methods:The expressions of NF-B,MMP-9 and COX-2 proteins in 52 specimens with osteosarcoma were determined by S-P immunohistochemical staining method,and 40 specimens of osteochondroma were served as control.Microvessel density were calculated with anti-CD34 monoclonal antibody stainning.Results:The positive expressions of NF-B,MMP-9 and COX-2 in osteosarcoma were significantly higher than those in osteochondroma(P0.05),there were positive correlations between the expressions of NF-B and MMP-9,NF-B and COX-2,and the close correlations were found between NF-B,MMP-9,NF-B and microvessel density.Conclusions:The expressions of NF-B,MMP-9 and COX-2 in osteosarcoma are all high.The three indexes may promote angiogenesis of osteosarcoma.
2013, 37(3): 273-275.
Abstract:
Objective:To evaluate the diagnostic value of endoscopic ultrasonography(EUS) in eminence lesion of the stomach.Methods:EUS and mini-probe sonography were performed in 186 patients with eminence lesion of the stomach which had been detected by the gastroscopy.Excepting for 45 cases of protuberance from outside organs,5 cases of sub-mucous hemartoma and 7 cases of varicosity,all the cases were confirmed by surgical operation or biopsy.The pathological and diagnostic results by the two methods were compared.Results:One hundred and four cases had sub-mucous tumors,most of which were gastric stromal tumors,and 82 nontumorous lesions,most of which were protuberance from outside organs.The diagnose accordance rate was 93.0% by EUS and 74.2% by endoscopy.The difference was significant(P0.01).Conclusions:EUS can display the layers of the digestive tract wall and the lesions outside the wall,which is of great help for the diagnosis and differential diagnosis of eminence lesion of the stomach.
Objective:To evaluate the diagnostic value of endoscopic ultrasonography(EUS) in eminence lesion of the stomach.Methods:EUS and mini-probe sonography were performed in 186 patients with eminence lesion of the stomach which had been detected by the gastroscopy.Excepting for 45 cases of protuberance from outside organs,5 cases of sub-mucous hemartoma and 7 cases of varicosity,all the cases were confirmed by surgical operation or biopsy.The pathological and diagnostic results by the two methods were compared.Results:One hundred and four cases had sub-mucous tumors,most of which were gastric stromal tumors,and 82 nontumorous lesions,most of which were protuberance from outside organs.The diagnose accordance rate was 93.0% by EUS and 74.2% by endoscopy.The difference was significant(P0.01).Conclusions:EUS can display the layers of the digestive tract wall and the lesions outside the wall,which is of great help for the diagnosis and differential diagnosis of eminence lesion of the stomach.
2013, 37(3): 275-277.
Abstract:
Objective:To study the etiology and clinical features of primary liver cancers(PLC).Methods:The age,gender,symptoms,liver function, fetoprotein(AFP) and imaging results of 177 patients with primary liver cancers were analyzed retrospectively.Results:The peak age of PLC was 40-60.The morbility of male and female was 3.43∶ 1.The infection rates of HBV and HCV were 75.14% and 0.56%,respectively.The positive rates of -glutamyl transferase(-GGT) and AFP were 73.45% and 74.58%,respectively.The rate of portal vein thrombosis and distant metastases were about 41.81% and 0.56%,respectively.Seventy-eight of the cases received surgical therapy.Among the 78 cases,68 were confirmed to be hepatocellular carcinoma(HCC) and 10 intrahepatic cholangiocarcinoma(ICC).The infection rate of HBV of the former(76.47%) was higher than that of the latter(10.00%)(P0.05);the positive rates of total bilirubin and alkaline phosphatase were 14.71% and 50.00% versus 17.65% and 60.00%(P0.05).Conclusions:The risk factors for PLC include ages above 40,male and infection of HBV.-GGT and AFP may be beneficial to the diagnosis of PLC.The most common metastasis of PLC is innerliver hematogenous metastasis.HCC is often observed in PLC.ICC patients usually have a high positive rate of alkaline phosphatase,which may be of help to the diagnosis of intrahepatic cholangiocarcinoma.
Objective:To study the etiology and clinical features of primary liver cancers(PLC).Methods:The age,gender,symptoms,liver function, fetoprotein(AFP) and imaging results of 177 patients with primary liver cancers were analyzed retrospectively.Results:The peak age of PLC was 40-60.The morbility of male and female was 3.43∶ 1.The infection rates of HBV and HCV were 75.14% and 0.56%,respectively.The positive rates of -glutamyl transferase(-GGT) and AFP were 73.45% and 74.58%,respectively.The rate of portal vein thrombosis and distant metastases were about 41.81% and 0.56%,respectively.Seventy-eight of the cases received surgical therapy.Among the 78 cases,68 were confirmed to be hepatocellular carcinoma(HCC) and 10 intrahepatic cholangiocarcinoma(ICC).The infection rate of HBV of the former(76.47%) was higher than that of the latter(10.00%)(P0.05);the positive rates of total bilirubin and alkaline phosphatase were 14.71% and 50.00% versus 17.65% and 60.00%(P0.05).Conclusions:The risk factors for PLC include ages above 40,male and infection of HBV.-GGT and AFP may be beneficial to the diagnosis of PLC.The most common metastasis of PLC is innerliver hematogenous metastasis.HCC is often observed in PLC.ICC patients usually have a high positive rate of alkaline phosphatase,which may be of help to the diagnosis of intrahepatic cholangiocarcinoma.
2013, 37(3): 278-279,282.
Abstract:
Objective:To compare the efficacy and safety of the triple treatmentyes helicobacter pylori(Hp) infection with rabeprazole and esomeprazole.Methods:Three hundred and eighty-one cases with Hp infected were randomly divided into group A(190 cases)and group B(191 cases),group A were treated with 40 mg of esomeprazole Once a day,1 g of amoxicillin 2 times a day,500 mg of clarithromycin 2 times a day for 7 days.Group B(191 cases) were treated with 20 mg of rabeprazole 2 times a day and the same amoxicillin and clarithromycin as group A.The effects of all cases were followed-up 12-16 weeks by gastroscope and 14C-urea breath test for rejecting gastroscope.Results:The eradication rates of group A were 89.5%(170 cases)and 90.6%(173 cases) in group B,the incidence of adverse reactions of group A were 4.21% and 6.81% in group B,which had no statistical significance(P0.05).Conclusions:The triple treatment Hp infection with rabeprazole and esomeprazole are efficacy and safety.
Objective:To compare the efficacy and safety of the triple treatmentyes helicobacter pylori(Hp) infection with rabeprazole and esomeprazole.Methods:Three hundred and eighty-one cases with Hp infected were randomly divided into group A(190 cases)and group B(191 cases),group A were treated with 40 mg of esomeprazole Once a day,1 g of amoxicillin 2 times a day,500 mg of clarithromycin 2 times a day for 7 days.Group B(191 cases) were treated with 20 mg of rabeprazole 2 times a day and the same amoxicillin and clarithromycin as group A.The effects of all cases were followed-up 12-16 weeks by gastroscope and 14C-urea breath test for rejecting gastroscope.Results:The eradication rates of group A were 89.5%(170 cases)and 90.6%(173 cases) in group B,the incidence of adverse reactions of group A were 4.21% and 6.81% in group B,which had no statistical significance(P0.05).Conclusions:The triple treatment Hp infection with rabeprazole and esomeprazole are efficacy and safety.
2013, 37(3): 280-282.
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Objective:To investigate the pathogeny of osteoporosis of patients with rheumatoid arthritis(RA),and the relationship between osteoporosis with severity of sickness.Methods:The bone density was determined by ultrasound.All cases were divided into osteoporosis and no-osteoporosis group.The anti-cyclic cicrullinated peptide(CCP) antibody was detected by enzyme linked immunosorbent assay for understanding the the relationship between osteoporosis with severity of sickness.Results:For osteoporosis group,the disease course was longer,and positive incidence of CCP and standard of RF was significantly higher than these of no-osteoporosis group(P0.05).But there were no significant difference in the age,sex,number of hurt and swollen articulation,erythrocyte sedimentation rate(ESR),C-reative protein(CRP) and parathyroid hormone(PTH) in the two groups(P0.05).Conclusions:It is very important for preserving capacity of labour and improving the patient survival qualities by examining bone density and early therapying osteoporosis of RA patients.
Objective:To investigate the pathogeny of osteoporosis of patients with rheumatoid arthritis(RA),and the relationship between osteoporosis with severity of sickness.Methods:The bone density was determined by ultrasound.All cases were divided into osteoporosis and no-osteoporosis group.The anti-cyclic cicrullinated peptide(CCP) antibody was detected by enzyme linked immunosorbent assay for understanding the the relationship between osteoporosis with severity of sickness.Results:For osteoporosis group,the disease course was longer,and positive incidence of CCP and standard of RF was significantly higher than these of no-osteoporosis group(P0.05).But there were no significant difference in the age,sex,number of hurt and swollen articulation,erythrocyte sedimentation rate(ESR),C-reative protein(CRP) and parathyroid hormone(PTH) in the two groups(P0.05).Conclusions:It is very important for preserving capacity of labour and improving the patient survival qualities by examining bone density and early therapying osteoporosis of RA patients.
2013, 37(3): 283-285.
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Objective:To investigate the clinical effects of the conservative operation combined with drugs in the treatment of endometriosis dysmenorrhea.Methods:Seventy-six patients with endometriosis dysmenorrhea were divide into control group(38 cases) who refused surgery and requested oral drugs and treatment group(38 cases) who were treated with conservative operation combined with drugs.The symptoms of dysmenorrhea,relapse and adverse reactions of all patients were followed up for 2 years after therapy.Results:The effective rate of the treatmet group(86.84%) was higher than that of control group(47.30%)(P0.01).The average incidence of gastrointestinal reaction,abnormal vaginal bleeding and weight gain of patients taking gestrinone,mifepristone and desogestrel ethinylestradiol were 18.42%,22.37% and 18.40%,respectively,which differences were not statistic significance(P0.05).Conclusions:Dysmenorrheal is one of the most common symptoms for endometriosis.The treatment of conservative operation combined with drugs can serve as the first choice.The postoperative drug selection may be based on individual adverse reactions.
Objective:To investigate the clinical effects of the conservative operation combined with drugs in the treatment of endometriosis dysmenorrhea.Methods:Seventy-six patients with endometriosis dysmenorrhea were divide into control group(38 cases) who refused surgery and requested oral drugs and treatment group(38 cases) who were treated with conservative operation combined with drugs.The symptoms of dysmenorrhea,relapse and adverse reactions of all patients were followed up for 2 years after therapy.Results:The effective rate of the treatmet group(86.84%) was higher than that of control group(47.30%)(P0.01).The average incidence of gastrointestinal reaction,abnormal vaginal bleeding and weight gain of patients taking gestrinone,mifepristone and desogestrel ethinylestradiol were 18.42%,22.37% and 18.40%,respectively,which differences were not statistic significance(P0.05).Conclusions:Dysmenorrheal is one of the most common symptoms for endometriosis.The treatment of conservative operation combined with drugs can serve as the first choice.The postoperative drug selection may be based on individual adverse reactions.
2013, 37(3): 285-287.
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Objective:To evaluate the clinical effects of treatment osteoporotic vertebral compression fractures(OVCF) with percutaneous vertebroplasty(PVP).Methods:One hundred and sixty-five vertebraes of 128 cases were treated with PVP by injection 2.7-9.5 ml of polymethyl-methacrylate.Results:All 165 vertebraes were punctured successful,in which 146 vertebraes were treated with unilateral transpedicular puncturing.The total efficiency of clinical pain relief was 95.3% and no serious complications.Conclusions:Treatment OVCF with PVP has good curative effects,small wound and broad indications.
Objective:To evaluate the clinical effects of treatment osteoporotic vertebral compression fractures(OVCF) with percutaneous vertebroplasty(PVP).Methods:One hundred and sixty-five vertebraes of 128 cases were treated with PVP by injection 2.7-9.5 ml of polymethyl-methacrylate.Results:All 165 vertebraes were punctured successful,in which 146 vertebraes were treated with unilateral transpedicular puncturing.The total efficiency of clinical pain relief was 95.3% and no serious complications.Conclusions:Treatment OVCF with PVP has good curative effects,small wound and broad indications.
2013, 37(3): 288-289,292.
Abstract:
Objective:To compare the pathology differences of cystoscopic biopsy and transurethral resection of bladder tumor(TURBT),and evaluate their diagnosis and treatment values in bladder tumor.Methods:The pathological grades of tumor with cystoscopic biopsy and TURBT of 122 cases were analysed.Results:The accordance rates of the pathological results of cystoscope biopsy and TURBT were 66.4%.Compared with pathological levels of postoperation,the pathological grades of 30 cases increased,and decreased in 11 cases,and the differences was statistically significant(P0.01).Conclusions:Preoperative pathological grades of cystoscopic biopsy are lower than that of postoperation,which may affect treatment program and should be paid more attention.
Objective:To compare the pathology differences of cystoscopic biopsy and transurethral resection of bladder tumor(TURBT),and evaluate their diagnosis and treatment values in bladder tumor.Methods:The pathological grades of tumor with cystoscopic biopsy and TURBT of 122 cases were analysed.Results:The accordance rates of the pathological results of cystoscope biopsy and TURBT were 66.4%.Compared with pathological levels of postoperation,the pathological grades of 30 cases increased,and decreased in 11 cases,and the differences was statistically significant(P0.01).Conclusions:Preoperative pathological grades of cystoscopic biopsy are lower than that of postoperation,which may affect treatment program and should be paid more attention.
2013, 37(3): 290-292.
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Objective:To compare the effects of treatment mixed elbow stiffness with the open arthrolysis and arthroscopic arthrolysis.Methods:Twenty-one cases with mixed elbow stiffness were treated with open arthrolysis,and the mean interval time between trauma and arthrolysis was 13.5 months,the other 21 cases were treated with arthroscopic arthrolysis as control,and the mean interval time was 12.9 months.The treatment effects of the open arthrolysis and arthroscopic arthrolysis were compared according to the criterions of range of motion(ROM) and elbow joint founction of Mayo.Results:All cases were followed up for 18 to 49 months.The postoperation scores of ROM and Mayo of all cases were significantly improved compared with that of preoperation(P0.01).The postoperation scores of the open arthrolysis group were better than that of the arthroscopic arthrolysis group(P0.01).Conclusions:The open arthrolysis and arthroscopic arthrolysis are safe and effective method for treating mixed elbow stiffness.Meanwhile,the open arthrolysis can better improve the motion range of elbow joint and promote its functional recovery than the arthroscopic arthrolysis group.
Objective:To compare the effects of treatment mixed elbow stiffness with the open arthrolysis and arthroscopic arthrolysis.Methods:Twenty-one cases with mixed elbow stiffness were treated with open arthrolysis,and the mean interval time between trauma and arthrolysis was 13.5 months,the other 21 cases were treated with arthroscopic arthrolysis as control,and the mean interval time was 12.9 months.The treatment effects of the open arthrolysis and arthroscopic arthrolysis were compared according to the criterions of range of motion(ROM) and elbow joint founction of Mayo.Results:All cases were followed up for 18 to 49 months.The postoperation scores of ROM and Mayo of all cases were significantly improved compared with that of preoperation(P0.01).The postoperation scores of the open arthrolysis group were better than that of the arthroscopic arthrolysis group(P0.01).Conclusions:The open arthrolysis and arthroscopic arthrolysis are safe and effective method for treating mixed elbow stiffness.Meanwhile,the open arthrolysis can better improve the motion range of elbow joint and promote its functional recovery than the arthroscopic arthrolysis group.
2013, 37(3): 293-294.
Abstract:
Objective:To investigate the psychotherapy effects on trichloromethyl carbonate poisoning.Methods:Forty-five patients were randomly divided into the treatment group and control group.These cases of the treatment group were treated with taking oxygen,antispasmodic,relieving asthma,expectorant,prevention infection,mechanical ventilation(for severe cases),conventional treatment combined with psychological treatment.However,cases in control group were only treated with conventional treatment.All cases were measured with Toronto Alexithymia scale,Self-Rating Anxiety Scale and Self-rating depression scale at 7 and 14 days before and after treatment,then data were conducted contrast analysis.Results:All cases had varying degrees anxiety and depression symptoms,and their differences had not statistically significant before treatment(P0.05).The anxiety and depression improved of treatment group were better than that of the control group at 7days after treatment,and the differences had statistically significant(P0.05).Before and after treatment,the degree of state of an illness of all cases had no significant difference(P0.05).Conclusions:The cases with trichloromethyl carbonate poisoning have varying degrees anxiety and depression symptoms.Conventional therapy combined with psychotherapy can shorten the course of treatment,and improve the cure rate of patients.
Objective:To investigate the psychotherapy effects on trichloromethyl carbonate poisoning.Methods:Forty-five patients were randomly divided into the treatment group and control group.These cases of the treatment group were treated with taking oxygen,antispasmodic,relieving asthma,expectorant,prevention infection,mechanical ventilation(for severe cases),conventional treatment combined with psychological treatment.However,cases in control group were only treated with conventional treatment.All cases were measured with Toronto Alexithymia scale,Self-Rating Anxiety Scale and Self-rating depression scale at 7 and 14 days before and after treatment,then data were conducted contrast analysis.Results:All cases had varying degrees anxiety and depression symptoms,and their differences had not statistically significant before treatment(P0.05).The anxiety and depression improved of treatment group were better than that of the control group at 7days after treatment,and the differences had statistically significant(P0.05).Before and after treatment,the degree of state of an illness of all cases had no significant difference(P0.05).Conclusions:The cases with trichloromethyl carbonate poisoning have varying degrees anxiety and depression symptoms.Conventional therapy combined with psychotherapy can shorten the course of treatment,and improve the cure rate of patients.
2013, 37(3): 295-297.
Abstract:
Objective:To explore the epidemiological and clinical characteristics of hand foot and mouth disease(HFMD).Methods:The treatment,epidemiological and clinical characteristics of 280 with HFMD were retrospective analysed from Oct.2008 to Oct.2009.Results:The cases with under 3 years were in majority,sporadic cases were major characteristics in epidemiology,and local pop performance in part of the kindergarten were found.Fever incidence was was 98.72%,and all the cases have rash.The performances of high fever,vomiting,body shaking,muscle weakness and sleepinessof the nervous system were found in severe cases,accounted for 20.36%.There were 4 cases with mycoplasma infection.In laboratory results,white blood cells(WBC) were greater than 10109/L in 266 cases;the binding force of carbon dioxide of 210 cases reduced;myocardial enzyme abnormal were in 77 cases,liver function abnormal were in 28 cases.In electrocardiogram(ECG),sinus tachycardia or too slow were main performances,sinus tachycardia was most,and S-T segment moving down and T-wave low plain was less.One case with antrum room knot free rhythm was detected.Fifty-one cases with ECG abnormalities,234 cases with bronchitis and 11 cases with bronchial pneumonia were comfirmed.Conclusions:Most cases with HFMD have light performances and are the common clinical cases.Rash have obvious characteristics.Sporadic cases are major features local pop performance are less in epidemiology.High fever,vomiting,body shaking,muscle weakness and sluggishness or sleepiness can hint heavy condition.Early application of hormones and immunoglobulin can relieve symptoms and promote the recovery of illness.
Objective:To explore the epidemiological and clinical characteristics of hand foot and mouth disease(HFMD).Methods:The treatment,epidemiological and clinical characteristics of 280 with HFMD were retrospective analysed from Oct.2008 to Oct.2009.Results:The cases with under 3 years were in majority,sporadic cases were major characteristics in epidemiology,and local pop performance in part of the kindergarten were found.Fever incidence was was 98.72%,and all the cases have rash.The performances of high fever,vomiting,body shaking,muscle weakness and sleepinessof the nervous system were found in severe cases,accounted for 20.36%.There were 4 cases with mycoplasma infection.In laboratory results,white blood cells(WBC) were greater than 10109/L in 266 cases;the binding force of carbon dioxide of 210 cases reduced;myocardial enzyme abnormal were in 77 cases,liver function abnormal were in 28 cases.In electrocardiogram(ECG),sinus tachycardia or too slow were main performances,sinus tachycardia was most,and S-T segment moving down and T-wave low plain was less.One case with antrum room knot free rhythm was detected.Fifty-one cases with ECG abnormalities,234 cases with bronchitis and 11 cases with bronchial pneumonia were comfirmed.Conclusions:Most cases with HFMD have light performances and are the common clinical cases.Rash have obvious characteristics.Sporadic cases are major features local pop performance are less in epidemiology.High fever,vomiting,body shaking,muscle weakness and sluggishness or sleepiness can hint heavy condition.Early application of hormones and immunoglobulin can relieve symptoms and promote the recovery of illness.
2013, 37(3): 298-300.
Abstract:
Objective:To investigate the clinical effects of total thyroidectomy(TT) and subtotal thyroidectomy(ST) in the treatment of bilateral multiple thyroid nodules.Methods:The data of 185 cases with bilateral multiple thyroid nodules were analysed retrospectively.The surgery and postoperative situation of patients treated with TT and ST were compared.Results:The blood loss and the identification rates of recurrent laryngeal nerve of all patients were not statistically significant different(P0.05).The operative time and the mean length of incision of patients treated with TT was significant longer than these treated with ST(P0.01).The identification height of parathyroid in patients treated with TT was significantly higher than these treated with ST(P0.01).The temporary and permanent damage of recurrent laryngeal nerve and the temporary and permanent hypofunction of parathyroid of patients treated with TT,ST were not statistically significant different(P0.05).No recurrent case was found in patients treated with TT and the recurrent rate in patients treated with ST was 18.3%,which difference was statistical significance(P0.01).Conclusions:The safety of operation and recent effects of TT and ST in the treatment of bilateral multiple thyroid nodules have no obvious differences.The recurrent rate in patients treated with TT is better than these treated with ST,TT is a worthly of spreading operation method in clinic.
Objective:To investigate the clinical effects of total thyroidectomy(TT) and subtotal thyroidectomy(ST) in the treatment of bilateral multiple thyroid nodules.Methods:The data of 185 cases with bilateral multiple thyroid nodules were analysed retrospectively.The surgery and postoperative situation of patients treated with TT and ST were compared.Results:The blood loss and the identification rates of recurrent laryngeal nerve of all patients were not statistically significant different(P0.05).The operative time and the mean length of incision of patients treated with TT was significant longer than these treated with ST(P0.01).The identification height of parathyroid in patients treated with TT was significantly higher than these treated with ST(P0.01).The temporary and permanent damage of recurrent laryngeal nerve and the temporary and permanent hypofunction of parathyroid of patients treated with TT,ST were not statistically significant different(P0.05).No recurrent case was found in patients treated with TT and the recurrent rate in patients treated with ST was 18.3%,which difference was statistical significance(P0.01).Conclusions:The safety of operation and recent effects of TT and ST in the treatment of bilateral multiple thyroid nodules have no obvious differences.The recurrent rate in patients treated with TT is better than these treated with ST,TT is a worthly of spreading operation method in clinic.
2013, 37(3): 300-302.
Abstract:
Objective:To investigate the safety,efficacy of surgical treatment uterine septum with uteroscope.Methods:Uterine septum of 123 cases were operated with uteroscope under normal saline or 5% glucose continuous injection.Results:In 123 cases,108 cases were full term pregnant childbirth,13 cases were abortion after pregnancy,and 2 cases were no pregnancy.None of them emerged side injury and complications.Conclusions:For treatment uterine septum with uteroscope,the effects are good,surgical pain is light,and recovery is quick.The operation can complete under local anesthesia,can maintain the integrity of reproductive organ,and return the fertility of the majority patients.
Objective:To investigate the safety,efficacy of surgical treatment uterine septum with uteroscope.Methods:Uterine septum of 123 cases were operated with uteroscope under normal saline or 5% glucose continuous injection.Results:In 123 cases,108 cases were full term pregnant childbirth,13 cases were abortion after pregnancy,and 2 cases were no pregnancy.None of them emerged side injury and complications.Conclusions:For treatment uterine septum with uteroscope,the effects are good,surgical pain is light,and recovery is quick.The operation can complete under local anesthesia,can maintain the integrity of reproductive organ,and return the fertility of the majority patients.
2013, 37(3): 303-305.
Abstract:
Objective:To evaluate the effects of treatment severe multiple trauma patients with gastrointestinal dysfunction with Xuebijing combined with Rhubarb.Methods:Fifty-two severe multiple trauma cases with gastrointestinal dysfunction were randomly divided into treatment group(n=27),which were treated with Xuebijing injection and Rhubarb and control group(n=25),which were not used the above measures.The treatment of original and other disease of two groups were the same.The effects of alleviative gastrointestinal dysfunction and morbidity of multiple organ dysfunction syndrome(MODS) of two groups were observed.Results:The gastrointestinal function scores and morbidity of MODS of the teatment group were significantly lower than that of the control group(P0.01).The effects of alleviative gastrointestinal dysfunction were significantly higher than that of the control group(P0.01).Conclusions:The treatment of Xuebijing combined with Rhubarb have good effects on severe multiple trauma patients with gastrointestinal dysfunction,and can reduce the morbidity of MODS.
Objective:To evaluate the effects of treatment severe multiple trauma patients with gastrointestinal dysfunction with Xuebijing combined with Rhubarb.Methods:Fifty-two severe multiple trauma cases with gastrointestinal dysfunction were randomly divided into treatment group(n=27),which were treated with Xuebijing injection and Rhubarb and control group(n=25),which were not used the above measures.The treatment of original and other disease of two groups were the same.The effects of alleviative gastrointestinal dysfunction and morbidity of multiple organ dysfunction syndrome(MODS) of two groups were observed.Results:The gastrointestinal function scores and morbidity of MODS of the teatment group were significantly lower than that of the control group(P0.01).The effects of alleviative gastrointestinal dysfunction were significantly higher than that of the control group(P0.01).Conclusions:The treatment of Xuebijing combined with Rhubarb have good effects on severe multiple trauma patients with gastrointestinal dysfunction,and can reduce the morbidity of MODS.
Experience of treatment in gastrointestinal leakage of 12 cases with gastric carcinoma postoperation
2013, 37(3): 307-309.
Abstract:
Objective:To summarize the therapeutic; experience of postoperative leakage of gastric caroinoma and to improve the treatment level. Methods:Twelve cases with the leakage of gastric caroinoma were treated with unobstructed drainage, gastrointestinal decompression, nutritional support and the somatostatin. Results:One case discharged himself outside, the others were recovered from the hospital. Conclusions:The measures of unobstructed drainage, decompression, nutritional support and somatostatin are important for promoting the recovery of digestive tract leakage.
Objective:To summarize the therapeutic; experience of postoperative leakage of gastric caroinoma and to improve the treatment level. Methods:Twelve cases with the leakage of gastric caroinoma were treated with unobstructed drainage, gastrointestinal decompression, nutritional support and the somatostatin. Results:One case discharged himself outside, the others were recovered from the hospital. Conclusions:The measures of unobstructed drainage, decompression, nutritional support and somatostatin are important for promoting the recovery of digestive tract leakage.
2013, 37(3): 311-316.
Abstract:
Objective:To investigate the prevention and control of chronic diseases in Hefei community health service agency,and the knowledge the staffs in charge have acquired about the prevention and control of chronic diseases.Methods:A total of one hundred and fifty community health service agencies which had been chosen from eighty percent of the community health service agencies in each district in Hefei seven administrative districts were investigated by self-made questionnaires.About the human resources,financial situation,current work capacity,personnel training and the knowledge they had acquired in the prevention and control of chronic diseases.Results:Among the 150 agencies,only 17.3%(26 agencies) had set a chronic disease department;the staffs involved in the prevention and control of chronic diseases account for 35.3% of the technicians;25.3% of these agencies did not have funds for the prevention and control of chronic diseases in 2008,and 40.7% had funds less than 20 000 yuan.Ninety-four point seven percent of the agencies had set up health records typed in paper,but only 66.0% had been analyzed.Fifty percent of the archives foundational information systems which had been established with the help of superior departments had never been used ever since.Majority of the 567 people investigated had graduated from the secondary or higher vocational colleges,and had engaged in chronic diseases for only two years(P50);78.6% of them possessed junior titles or below;80.6% of them had participated the prevention and control of chronic disease training,in county or city.The staffs made less correct answers in tests about malignant tumor and cardiovascular disease than in high blood pressure and diabetes mellitus apparently.People who had received professional training or had worked for over 4 years scored higher in the test than those who had not(P=0.006 and P=0.010).Conclusions:The organization construction and personnel building about the prevention and control of chronic diseases in Hefei community health services have improved greatly.However,when compared with the national average level and some areas,the difference is still significant.The prevention and control of chronic diseases should be strengthened and supports such as funds,policy and personnel should be provided.
Objective:To investigate the prevention and control of chronic diseases in Hefei community health service agency,and the knowledge the staffs in charge have acquired about the prevention and control of chronic diseases.Methods:A total of one hundred and fifty community health service agencies which had been chosen from eighty percent of the community health service agencies in each district in Hefei seven administrative districts were investigated by self-made questionnaires.About the human resources,financial situation,current work capacity,personnel training and the knowledge they had acquired in the prevention and control of chronic diseases.Results:Among the 150 agencies,only 17.3%(26 agencies) had set a chronic disease department;the staffs involved in the prevention and control of chronic diseases account for 35.3% of the technicians;25.3% of these agencies did not have funds for the prevention and control of chronic diseases in 2008,and 40.7% had funds less than 20 000 yuan.Ninety-four point seven percent of the agencies had set up health records typed in paper,but only 66.0% had been analyzed.Fifty percent of the archives foundational information systems which had been established with the help of superior departments had never been used ever since.Majority of the 567 people investigated had graduated from the secondary or higher vocational colleges,and had engaged in chronic diseases for only two years(P50);78.6% of them possessed junior titles or below;80.6% of them had participated the prevention and control of chronic disease training,in county or city.The staffs made less correct answers in tests about malignant tumor and cardiovascular disease than in high blood pressure and diabetes mellitus apparently.People who had received professional training or had worked for over 4 years scored higher in the test than those who had not(P=0.006 and P=0.010).Conclusions:The organization construction and personnel building about the prevention and control of chronic diseases in Hefei community health services have improved greatly.However,when compared with the national average level and some areas,the difference is still significant.The prevention and control of chronic diseases should be strengthened and supports such as funds,policy and personnel should be provided.
2013, 37(3): 317-320,323.
Abstract:
Objective:To investigate the prevalence and major risk factors of fatty liver in the workers of Shanghai postal and telecommunication company.Methods:A cross-sectional survey was performed in the workers who worked in Shanghai postal and telecommunication company from January to December 2011,all kinds of examinations were done in these workers,including physical examination,liver and renal function,serum fasting blood glucose level,lipid level,uric acid level and abdominal ultrasonographic examination.Results:Fatty liver was detected with abdominal ultrasonographic examination in 6 347 workers(33.58%),including 5 114 males(45.15%) and 1 233 females(16.28%).The prevalence of fatty liver in males was significantly higher than in females(P0.01).The prevalence of fatty liver was increased with aging both in males and females.Serum low-density lipoprotein cholesterol level,body mass index,triglyceride level,mean age,serum fasting glucose level,ALT level,serum uric acid and diastolic blood pressure in fatty liver group were significantly higher than those in the group without fatty liver(P0.01),but high-density lipoprotein cholesterol level in fatty liver group was significantly lower than in the group without fatty liver(P0.01).Conclusions:There is a high prevalence of fatty liver in the workers of Shanghai postal and telecommunication company.The prevalence of fatty liver in males is significantly higher than that in females.Obesity,diabetes,dyslipidemia,ages,hypertension and hyperuricemia are the major risk factors in nonalcoholic fatty liver.
Objective:To investigate the prevalence and major risk factors of fatty liver in the workers of Shanghai postal and telecommunication company.Methods:A cross-sectional survey was performed in the workers who worked in Shanghai postal and telecommunication company from January to December 2011,all kinds of examinations were done in these workers,including physical examination,liver and renal function,serum fasting blood glucose level,lipid level,uric acid level and abdominal ultrasonographic examination.Results:Fatty liver was detected with abdominal ultrasonographic examination in 6 347 workers(33.58%),including 5 114 males(45.15%) and 1 233 females(16.28%).The prevalence of fatty liver in males was significantly higher than in females(P0.01).The prevalence of fatty liver was increased with aging both in males and females.Serum low-density lipoprotein cholesterol level,body mass index,triglyceride level,mean age,serum fasting glucose level,ALT level,serum uric acid and diastolic blood pressure in fatty liver group were significantly higher than those in the group without fatty liver(P0.01),but high-density lipoprotein cholesterol level in fatty liver group was significantly lower than in the group without fatty liver(P0.01).Conclusions:There is a high prevalence of fatty liver in the workers of Shanghai postal and telecommunication company.The prevalence of fatty liver in males is significantly higher than that in females.Obesity,diabetes,dyslipidemia,ages,hypertension and hyperuricemia are the major risk factors in nonalcoholic fatty liver.
2013, 37(3): 321-323.
Abstract:
Objective:To explore the epidemic characters of hypertensive disease of rural residents in Anhui and provide the reference for its prevention and control.Methods:The subjects were rural residents seleted by multi-stage cluster random sampling method from 25 counties,who were interviewed with self-compiled questionnaire.Results:The hypertension,male and female prevalence rates were 12.06%,12.39% and 11.71%,respectively.According to the multi-factor logistic regression analysis,irregular diet,mental tension,aging and dietary preference were risk factors of hypertensive disease(P0.05 to P0.01).Conclusions:The hypertensive disease situation is not promising in rural area.It is high time to enhance rural health education directing at the main and easily changeable risk factors.
Objective:To explore the epidemic characters of hypertensive disease of rural residents in Anhui and provide the reference for its prevention and control.Methods:The subjects were rural residents seleted by multi-stage cluster random sampling method from 25 counties,who were interviewed with self-compiled questionnaire.Results:The hypertension,male and female prevalence rates were 12.06%,12.39% and 11.71%,respectively.According to the multi-factor logistic regression analysis,irregular diet,mental tension,aging and dietary preference were risk factors of hypertensive disease(P0.05 to P0.01).Conclusions:The hypertensive disease situation is not promising in rural area.It is high time to enhance rural health education directing at the main and easily changeable risk factors.
2013, 37(3): 326-328.
Abstract:
Objective:To explore the imaging of angiography of non-ST segment elevation acute coronary syndrome(NSTEACS) under 64-dector CT.Methods:Coronary artery angiography of twenty normal persons and thirty-five patients with NSTEACS were detected using 64-detector computed tomography,64-MDCT.The data of the lesion site,vessel involved number,plaque nature(calcified plaque,non-calcified plaque or mixed plaque),stenosis(degree and length) and the obstructed vessel were analysed.Results:There was significant statistic difference in the incidence of calcified plaque and plaques involving the coronary artery number(P0.01),but no significant statistic difference in myocardial bridge and plaque site(P0.05),and the narrow rates of coronary artery ranged from 15% to 100% in NSTEACS group.Conclusions:The imaging features of NSTEACS show extensive calcified plaque,multiple vessels involved and the wide stenosis of coronary artery,which can guide.clinical service.
Objective:To explore the imaging of angiography of non-ST segment elevation acute coronary syndrome(NSTEACS) under 64-dector CT.Methods:Coronary artery angiography of twenty normal persons and thirty-five patients with NSTEACS were detected using 64-detector computed tomography,64-MDCT.The data of the lesion site,vessel involved number,plaque nature(calcified plaque,non-calcified plaque or mixed plaque),stenosis(degree and length) and the obstructed vessel were analysed.Results:There was significant statistic difference in the incidence of calcified plaque and plaques involving the coronary artery number(P0.01),but no significant statistic difference in myocardial bridge and plaque site(P0.05),and the narrow rates of coronary artery ranged from 15% to 100% in NSTEACS group.Conclusions:The imaging features of NSTEACS show extensive calcified plaque,multiple vessels involved and the wide stenosis of coronary artery,which can guide.clinical service.
2013, 37(3): 329-331.
Abstract:
Objective:To investigate the application value of transthoracic echocardiography in the interventional occlusion of congenital heart disease.Methods:The applications of transthoracic echocardiography in the interventional occlusion of 82 cases with congenital heart disease(including 35 cases of atrial septal defect,30 cases of ventricular septal defect and 17 cases of patent ductus arteriosus) were analyzed and summarized.Results:The blocks in 77(including 32 cases of atrial septal defect,28 cases of ventricular septal defect and 17 cases of patent ductus arteriosus) of 82 cases were successful,and the success rate was 94%.Two cases occurred complications.Conclusions:The application of transthoracic echocardiography in the interventional occlusion of congenital heart disease is simple and success rate is high.
Objective:To investigate the application value of transthoracic echocardiography in the interventional occlusion of congenital heart disease.Methods:The applications of transthoracic echocardiography in the interventional occlusion of 82 cases with congenital heart disease(including 35 cases of atrial septal defect,30 cases of ventricular septal defect and 17 cases of patent ductus arteriosus) were analyzed and summarized.Results:The blocks in 77(including 32 cases of atrial septal defect,28 cases of ventricular septal defect and 17 cases of patent ductus arteriosus) of 82 cases were successful,and the success rate was 94%.Two cases occurred complications.Conclusions:The application of transthoracic echocardiography in the interventional occlusion of congenital heart disease is simple and success rate is high.
2013, 37(3): 331-333.
Abstract:
Objective:To explore the value of clinical application of computer X-ray in decreasing X-ray dose during the chest bedside photograph of the newborn.Methods:One hundred newborns irradiated by FUJI-IP with mobile bedside X-ray machine and 100 images were obtained.All newborns were randomly divided into group A and group B(50 cases each group).Group A and B were irradiated with the lowest and conventional mAs,respectively.The radiation doses,picture quality and minute structure of the image of two groups and its value of clinical application were recorded and analyzed statistically.Results:The radiation doses of group A and B were(0.029 50.030 57)mSv and(0.135 10.036 27) mSv,respectively,which difference was statistical significance(t=15.74,P0.01).The differences of the piece rate and minute structure of the image of group A and B were not statistical significance(P0.05).Conclusions:Utilizing the existing equipments,the radiation dose can be decreased by altering projection condition of bedside photograph,which does not affect the diagnosis.
Objective:To explore the value of clinical application of computer X-ray in decreasing X-ray dose during the chest bedside photograph of the newborn.Methods:One hundred newborns irradiated by FUJI-IP with mobile bedside X-ray machine and 100 images were obtained.All newborns were randomly divided into group A and group B(50 cases each group).Group A and B were irradiated with the lowest and conventional mAs,respectively.The radiation doses,picture quality and minute structure of the image of two groups and its value of clinical application were recorded and analyzed statistically.Results:The radiation doses of group A and B were(0.029 50.030 57)mSv and(0.135 10.036 27) mSv,respectively,which difference was statistical significance(t=15.74,P0.01).The differences of the piece rate and minute structure of the image of group A and B were not statistical significance(P0.05).Conclusions:Utilizing the existing equipments,the radiation dose can be decreased by altering projection condition of bedside photograph,which does not affect the diagnosis.
2013, 37(3): 333-334,337.
Abstract:
Objective:To analyze the ultrasonic features and causes for misdiagnosis of primary carcinoma of gallbladder(PCG) in order to improve the diagnosis rate.Methods:Thirty cases of PCG proved by pathology after operation were reviewed retrospectively,ultrasound examination after 8 h fasting.The shape,size,wall thickness and intracavity echo of the gallbladder,the liver and the exterior and interior of the hepatic bile were observed carefully to find out the ultrasonic features of PCG,and the causes for misdiagnosis were analysed.Results:In the 30 cases of PCG,18 were diagnosed by ultrasonography and 12 were misdiagnosed.Twenty-four of the cases were complicated with gallbladder stones and 6 cases gallbladder polyps,4 cases were found to have liver metastasis and 2 hilar lymph nodes.Conclusions:The ultrasonic manifestation of PCG is complex and diverse.Color Doppler ultrasound may help to improve the early diagnosis rate of PCG and reduce misdiagnosis.
Objective:To analyze the ultrasonic features and causes for misdiagnosis of primary carcinoma of gallbladder(PCG) in order to improve the diagnosis rate.Methods:Thirty cases of PCG proved by pathology after operation were reviewed retrospectively,ultrasound examination after 8 h fasting.The shape,size,wall thickness and intracavity echo of the gallbladder,the liver and the exterior and interior of the hepatic bile were observed carefully to find out the ultrasonic features of PCG,and the causes for misdiagnosis were analysed.Results:In the 30 cases of PCG,18 were diagnosed by ultrasonography and 12 were misdiagnosed.Twenty-four of the cases were complicated with gallbladder stones and 6 cases gallbladder polyps,4 cases were found to have liver metastasis and 2 hilar lymph nodes.Conclusions:The ultrasonic manifestation of PCG is complex and diverse.Color Doppler ultrasound may help to improve the early diagnosis rate of PCG and reduce misdiagnosis.
2013, 37(3): 335-337.
Abstract:
Objective:To investigate the clinical value of the ultrasonic examination in the diagnosis of gallbladder perforation.Methods:The ultrasonic images of 51 cases with suspected acute cholecystitis were investigated.The size,shape,cystwall,the surrounding tissues of gallbladder and abdominal cavity were observed through the longitudinal,horizontal,and multidimensional scaning of the right upper abdomen of patients.The ultrasonographic findings were compared with operation and pathological examination.Results:Fifty-one of 58 cases with gallbladder perforation were diagnosised by ultrasonography and the coincidence rates were 87.93%.The ultrasonic imaging had characteristic changes,which was easy to diagnose and differentially diagnose.Conclusions:The ultrasonography has high veracities,which can determine the parts of the perforation and display the surrounding tissues of gallbladder and abdominal cavity.It may be a major means to detect perforation of gallbladder and has a high practical value.
Objective:To investigate the clinical value of the ultrasonic examination in the diagnosis of gallbladder perforation.Methods:The ultrasonic images of 51 cases with suspected acute cholecystitis were investigated.The size,shape,cystwall,the surrounding tissues of gallbladder and abdominal cavity were observed through the longitudinal,horizontal,and multidimensional scaning of the right upper abdomen of patients.The ultrasonographic findings were compared with operation and pathological examination.Results:Fifty-one of 58 cases with gallbladder perforation were diagnosised by ultrasonography and the coincidence rates were 87.93%.The ultrasonic imaging had characteristic changes,which was easy to diagnose and differentially diagnose.Conclusions:The ultrasonography has high veracities,which can determine the parts of the perforation and display the surrounding tissues of gallbladder and abdominal cavity.It may be a major means to detect perforation of gallbladder and has a high practical value.
2013, 37(3): 339-342.
Abstract:
Objective:To investigate the drug resistance of Klebsiellu pueumouiue isolated from different infection positions and guide the clinical rational medication.Methods:From Jan.2010 to Sep.2011,the extended-sprctrum -lactamases(ESBLs) of 260 strains of Klebsiellu pueumouiue isolated from different infection positions were detected using ATB EXPRESSION semi-automatic microorganism analyzer according to the standard of the clinical and Laboratory Standards Association recommending diagnostic tests.Results:The detection rates of ESBLs and drug resistance to ciprofloxacin,cefotaxime,cefuroxime,imipenem,meropenem,piperacillin and ticarcillin/clavulanate of Klebsiellu pueumouiue isolated from 2011 year were higher than that from 2010 year(P0.05 to P0.01).The drug resistance to cefotaxime,piperacillin and tazobactam of Klebsiella pneumoniae isolated from infection position was lower than that from non-infection position(P0.05).There were not significant difference between the detection rate of ESBLs and drug resistance to 20 kinds of antibiotics in the older group and young adults group(P0.05).Conclusions:The drug resistance has different characteristics in different infection postions.The antibacterial drug should be reasonably used according to different characteristics in clinic,which can delay the emergence of drug resistance of bacteria.
Objective:To investigate the drug resistance of Klebsiellu pueumouiue isolated from different infection positions and guide the clinical rational medication.Methods:From Jan.2010 to Sep.2011,the extended-sprctrum -lactamases(ESBLs) of 260 strains of Klebsiellu pueumouiue isolated from different infection positions were detected using ATB EXPRESSION semi-automatic microorganism analyzer according to the standard of the clinical and Laboratory Standards Association recommending diagnostic tests.Results:The detection rates of ESBLs and drug resistance to ciprofloxacin,cefotaxime,cefuroxime,imipenem,meropenem,piperacillin and ticarcillin/clavulanate of Klebsiellu pueumouiue isolated from 2011 year were higher than that from 2010 year(P0.05 to P0.01).The drug resistance to cefotaxime,piperacillin and tazobactam of Klebsiella pneumoniae isolated from infection position was lower than that from non-infection position(P0.05).There were not significant difference between the detection rate of ESBLs and drug resistance to 20 kinds of antibiotics in the older group and young adults group(P0.05).Conclusions:The drug resistance has different characteristics in different infection postions.The antibacterial drug should be reasonably used according to different characteristics in clinic,which can delay the emergence of drug resistance of bacteria.
2013, 37(3): 343-345.
Abstract:
Objective:To compare the detection results of HBV-M and HBV-DNA.Methods:All 388 HBV patients were detected for the HBV-M by ELISA and HBV-DNA by FQ-PCR.Results:The positive rate of HBV-DNA in the group of HBsAg(+)/HBeAg(+)/HBcAb(+) was 91.25%,and the majority of the virus replication was 107 IU/ml;while the majority of the virus replication in the group of HBsAg(+)/HBeAb(+)/ HBcAb(+) was 103 IU/ml.The positive rate of HBV-DNA in the group of HBsAgAb(+)/HBeAg(+)/HBc(+) was higher than that in the group of HBsAg(+)/HBeAb(+)/HBcAb(+)(P0.05).The positive rate of HBV-DNA in the group of HBsAg(+)/HBeAg()/ HBc(+)Ab was 66.67%.The majority of the virus replication was 105 IU/ml and 106 IU/ml in patients with positive HBsAg(+)/HBeAg(+)/HBc(-)Ab.The positive rate of HBV-DNA in the group of HBsAg(+)/HBeAg(-)/HBcAb(+) was 30.77%.Conclusions:Patients with HBeAg(+) have the highest replication level in all the groups,which is closely associated with HBV-DNA.Virus replication in patients with HBeAb(+) and HBcAb(+) does not stop completely,but obviously decreases.Combination detection of HBV-M and HBV-DNA may display the immune status and virus replication level of patients with hepatitis B,which would provide experimental basis for clinical monitoring and drug administration.
Objective:To compare the detection results of HBV-M and HBV-DNA.Methods:All 388 HBV patients were detected for the HBV-M by ELISA and HBV-DNA by FQ-PCR.Results:The positive rate of HBV-DNA in the group of HBsAg(+)/HBeAg(+)/HBcAb(+) was 91.25%,and the majority of the virus replication was 107 IU/ml;while the majority of the virus replication in the group of HBsAg(+)/HBeAb(+)/ HBcAb(+) was 103 IU/ml.The positive rate of HBV-DNA in the group of HBsAgAb(+)/HBeAg(+)/HBc(+) was higher than that in the group of HBsAg(+)/HBeAb(+)/HBcAb(+)(P0.05).The positive rate of HBV-DNA in the group of HBsAg(+)/HBeAg()/ HBc(+)Ab was 66.67%.The majority of the virus replication was 105 IU/ml and 106 IU/ml in patients with positive HBsAg(+)/HBeAg(+)/HBc(-)Ab.The positive rate of HBV-DNA in the group of HBsAg(+)/HBeAg(-)/HBcAb(+) was 30.77%.Conclusions:Patients with HBeAg(+) have the highest replication level in all the groups,which is closely associated with HBV-DNA.Virus replication in patients with HBeAb(+) and HBcAb(+) does not stop completely,but obviously decreases.Combination detection of HBV-M and HBV-DNA may display the immune status and virus replication level of patients with hepatitis B,which would provide experimental basis for clinical monitoring and drug administration.
2013, 37(3): 345-346,377.
Abstract:
Objective:To investigate the distribution and correlation of the disinfectants-sulfanilamide drug resistant phenotypes and genotypes in Aciuetobacter baumauuii(Aba) in Zhongshan district.Methods:The senior expert system of VITEK-2 Compact was used to judge the disinfectants-sulfanilamide drug resistant phenotypes in 405 strains Aba from Jan.2010 to Sep.2010,and the qacE△1-sul1 genes were detected by PCR in 30 strains multi-drug resistant Aba.Results:In the phenotypic mode of 405 strains Aba,the phenotypic mode of RESISTANT was 201 strains(49.6%),the phenotypic mode of WILD was 185 strains(45.7%),the phenotypic mode of RESISTANT +WILD was 19 strains(4.7%).In the disinfectants-sulfanilamide drug resistant phenotypes mode of 30 strains Aba,phenotypic mode of RESISTANT was 12 strains Aba,the phenotypic mode of WILD was 15 strains,the phenotypic mode of RESISTANT+WILD was 3 strains.Conclusions:The multiple drug-resistant of the separation Aba is serious,the carrier rate of the qacE△1-sul1 gene is 100%.
Objective:To investigate the distribution and correlation of the disinfectants-sulfanilamide drug resistant phenotypes and genotypes in Aciuetobacter baumauuii(Aba) in Zhongshan district.Methods:The senior expert system of VITEK-2 Compact was used to judge the disinfectants-sulfanilamide drug resistant phenotypes in 405 strains Aba from Jan.2010 to Sep.2010,and the qacE△1-sul1 genes were detected by PCR in 30 strains multi-drug resistant Aba.Results:In the phenotypic mode of 405 strains Aba,the phenotypic mode of RESISTANT was 201 strains(49.6%),the phenotypic mode of WILD was 185 strains(45.7%),the phenotypic mode of RESISTANT +WILD was 19 strains(4.7%).In the disinfectants-sulfanilamide drug resistant phenotypes mode of 30 strains Aba,phenotypic mode of RESISTANT was 12 strains Aba,the phenotypic mode of WILD was 15 strains,the phenotypic mode of RESISTANT+WILD was 3 strains.Conclusions:The multiple drug-resistant of the separation Aba is serious,the carrier rate of the qacE△1-sul1 gene is 100%.
2013, 37(3): 351-354.
Abstract:
Objective:To evaluate the effect of therapeutic communication on the illness uncertainty of preoperative patients with colorectal cancer.Methods:Sixty-seven patients with primary colorectal cancer were divided into the experimental group(35 cases) and the control group(32 cases).All the patients received routine preoperative care and communication.In addition,therapeutic communication was provided for the experimental group.The illness uncertainty was evaluated at admission afternoon and the day before operation.Results:Total uncertainty and four factor scores of two group had no significant differences before the intervention(P0.05).After the intervention,the scores of uncertainty,ambiguity,lack of information and complexity of experimental group were significantly lower than those of the control group(P0.05 to P0.01).There was no significantly difference in the scores of unpredictability(P0.05).Conclusions:Nursing intervention based on the therapeutic communication system is an effective approach in reducing the illness uncertainty of preoperative patients with colorectal cancer
Objective:To evaluate the effect of therapeutic communication on the illness uncertainty of preoperative patients with colorectal cancer.Methods:Sixty-seven patients with primary colorectal cancer were divided into the experimental group(35 cases) and the control group(32 cases).All the patients received routine preoperative care and communication.In addition,therapeutic communication was provided for the experimental group.The illness uncertainty was evaluated at admission afternoon and the day before operation.Results:Total uncertainty and four factor scores of two group had no significant differences before the intervention(P0.05).After the intervention,the scores of uncertainty,ambiguity,lack of information and complexity of experimental group were significantly lower than those of the control group(P0.05 to P0.01).There was no significantly difference in the scores of unpredictability(P0.05).Conclusions:Nursing intervention based on the therapeutic communication system is an effective approach in reducing the illness uncertainty of preoperative patients with colorectal cancer
2013, 37(3): 355-358.
Abstract:
Objective:To know the status of nurses job satisfaction and organizational commitment in operating room and explore the correlation of both.Methods:Two hundred and fourteen nurses of operating room from 6 Grade 3 general hospitals were investigated using the questionnaires of organizational commitment and job satisfaction.Results:The average scores of organizational commitment and job satisfaction were 2.740.50 and 2.820.63,respectively,and which was positively correlated(P0.01).There were no statistically significant difference between the score of organizational commitment in different genders and job satisfaction in different work purposes(P0.05).There were statistical significance between job satisfaction in predicting the total average score of organizational commitment on the basis of controlling the demographic variables(P0.01).The explained variance increased 21.9%,but when gender and work purpose entered into the regression equation,the score of job satisfaction could not obviously effect the score of organizational commitment(P0.05).Conclusions:Playing attention to the level of job satisfaction and taking some incentive measures can improve the level of satisfaction,promote organizational commitment,stabilize nursing team and alleviate the lack of nursing staff.
Objective:To know the status of nurses job satisfaction and organizational commitment in operating room and explore the correlation of both.Methods:Two hundred and fourteen nurses of operating room from 6 Grade 3 general hospitals were investigated using the questionnaires of organizational commitment and job satisfaction.Results:The average scores of organizational commitment and job satisfaction were 2.740.50 and 2.820.63,respectively,and which was positively correlated(P0.01).There were no statistically significant difference between the score of organizational commitment in different genders and job satisfaction in different work purposes(P0.05).There were statistical significance between job satisfaction in predicting the total average score of organizational commitment on the basis of controlling the demographic variables(P0.01).The explained variance increased 21.9%,but when gender and work purpose entered into the regression equation,the score of job satisfaction could not obviously effect the score of organizational commitment(P0.05).Conclusions:Playing attention to the level of job satisfaction and taking some incentive measures can improve the level of satisfaction,promote organizational commitment,stabilize nursing team and alleviate the lack of nursing staff.
2013, 37(3): 358-360.
Abstract:
Objective:To evaluate the effect of systematic health education on patients with CT enhanced scan.Methods:Sixty eight patients were divided into the observation group and the control group.All these patients accepted the CT enhanced scan for the first time.Patients in the observation group accept systematic health education,and patients in the control group accepted the routine health education.Evaluated the patients' scores of self-rating depressive scale(SAS) and recorded incidence rate of the adverse reactions.Results:Compared with patients from the control group,patients from the observation group showed a lower level of anxiety and a lower occurrence rate of adverse reactions during and after the process(P0.01).Conclusions:Systematic Health Education can efficiently alleviate the anxiety and reduce the occurrence of adverse reactions of patients with CT enhanced scan.
Objective:To evaluate the effect of systematic health education on patients with CT enhanced scan.Methods:Sixty eight patients were divided into the observation group and the control group.All these patients accepted the CT enhanced scan for the first time.Patients in the observation group accept systematic health education,and patients in the control group accepted the routine health education.Evaluated the patients' scores of self-rating depressive scale(SAS) and recorded incidence rate of the adverse reactions.Results:Compared with patients from the control group,patients from the observation group showed a lower level of anxiety and a lower occurrence rate of adverse reactions during and after the process(P0.01).Conclusions:Systematic Health Education can efficiently alleviate the anxiety and reduce the occurrence of adverse reactions of patients with CT enhanced scan.
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