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2015 Vol. 40, No. 3
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2015, 40(3): 283-289.
doi: 10.13898/j.cnki.issn.1000-2200.2015.03.002
Abstract:
Objective:To investigate the residents evaluation on new medical reform policy performance for providing the evidence in adjusting the public health and improving the health policy measure of decision-making department.Methods:Three thousand five hundred and eleven urban and rural residents from 18 provinces and cities mainly in Anhui province were investigated using the self-designed "the Questionare on New Medical Reform Policy Performance from Urban and Rural Resident's Evalution" by a convenience sampling method.Results:Nine hundred and twenty-one people in 3501 people(26.3%) believed that the current medical and health policy were fair;1155 people in 3497 people(33.0%) thought that the medicine and health policy were generally efficient.Eight hundred and thirty-eight people in 3506 people(23.9%) believed that the equity was the most important in health reform,558 people(15.9%) believed that the efficiency was the most important,and 2 110 people(60.2%) thought that both were important.Three hundred and sixty-six people in 3500 people(10.5%) thought that the medical and health reform and supervision system were perfect,662 people in 3492(19.0%) believed that the current health system reform was generally successful,1141 people in 3435 people(33.2%) thought that the Chinese medical and health system reform welfare policy was likely to achieve.Seven hundred and fifty-five people in 3493(21.6%) were satisfied with the current health system reform,629 people(18.0%) were not satisfied.The evaluation differences of both genders on "Do you think Chinese medical and health system reform welfare policy is likely to be achieved?" were not statistically significant(P>0.05),but they had statistically significant on the ther seven questions(P<0.05 to P<0.01).The evaluation differences of different educational levels on"What do you think is the most important thing in the health reform,fairness or efficiency?" were not statistically significant(P>0.05),but they had statistically significant on the other seven questions(P<0.01). The evaluation differences of different ages on all questions were statistically significant(P>0.05).Conclusions:There is a certain gap between the medical reform effects and social expectations.Residents pursue the fairness,efficiency and public welfare in medical reform,and they hope to further improve the medical and health reform's supervision system.
Objective:To investigate the residents evaluation on new medical reform policy performance for providing the evidence in adjusting the public health and improving the health policy measure of decision-making department.Methods:Three thousand five hundred and eleven urban and rural residents from 18 provinces and cities mainly in Anhui province were investigated using the self-designed "the Questionare on New Medical Reform Policy Performance from Urban and Rural Resident's Evalution" by a convenience sampling method.Results:Nine hundred and twenty-one people in 3501 people(26.3%) believed that the current medical and health policy were fair;1155 people in 3497 people(33.0%) thought that the medicine and health policy were generally efficient.Eight hundred and thirty-eight people in 3506 people(23.9%) believed that the equity was the most important in health reform,558 people(15.9%) believed that the efficiency was the most important,and 2 110 people(60.2%) thought that both were important.Three hundred and sixty-six people in 3500 people(10.5%) thought that the medical and health reform and supervision system were perfect,662 people in 3492(19.0%) believed that the current health system reform was generally successful,1141 people in 3435 people(33.2%) thought that the Chinese medical and health system reform welfare policy was likely to achieve.Seven hundred and fifty-five people in 3493(21.6%) were satisfied with the current health system reform,629 people(18.0%) were not satisfied.The evaluation differences of both genders on "Do you think Chinese medical and health system reform welfare policy is likely to be achieved?" were not statistically significant(P>0.05),but they had statistically significant on the ther seven questions(P<0.05 to P<0.01).The evaluation differences of different educational levels on"What do you think is the most important thing in the health reform,fairness or efficiency?" were not statistically significant(P>0.05),but they had statistically significant on the other seven questions(P<0.01). The evaluation differences of different ages on all questions were statistically significant(P>0.05).Conclusions:There is a certain gap between the medical reform effects and social expectations.Residents pursue the fairness,efficiency and public welfare in medical reform,and they hope to further improve the medical and health reform's supervision system.
2015, 40(3): 290-295.
doi: 10.13898/j.cnki.issn.1000-2200.2015.03.003
Abstract:
Objective:To investigate the awareness,utilization and satisfaction of community health center/station in more than 60 years of age residents for providing the basis in the rational allocation of health care resource.Methods:Seven hundred permanent more than 60 years of age residents in Yuhui District of Bengbu City were investigated using the self-made "community health service center/station awareness,utilization and satisfaction survey questionnaire" by the stratified cluster sampling method.Results:The 679 valid questionnaires were withdrew,the effective rate of which was 97.0%,the awareness and utilization rates of the community health service center/station were 84.1% and 58.2%,respectively.The main purposes of utilizing the community health service center/station were seeing a doctor(72.2%),prescriptions(54.2%),following-up(10.8%),medical consultation(0.3%),physiotherapy(1.0%) and listening the health knowledge lecture(4.1%).Overall satisfaction was 78.2%.Satisfaction from high to low in the order were the interpretation of the medical staff,communication and service content(82.3%),medical environment(79.5%),medical staff service attitude(78.2%),the convenient degree of seeing a doctor(76.7%),waiting or queuing time(76.5%),facilities and equipment(76.5%),medical price(65.6%) and medical cost(63.0%),whose were higher than the general and partial satisfaction of other medical institution(P<0.01).The residents proportions of worrying about infecting with disease and misdiagnosis were 14.9% and 20.8% in the treatment process,respectively,the worry degree of who was lower than that of other medical institution(P<0.01).Logistics regression analysis showed that the age and marital status,suffering from chronic diseases,trust in medical institution were important factors of satisfaction and utilizing community health service center/station(P<0.05~P<0.01).Conclusions:The awareness,utilization and satisfaction of community health service center/station in more than 60 years of age residents in Yuhui District of Bengbu City are high,but the participation rate of health knowledge lecture is low.Community health service institutions should target to carry out the work based on the characteristics of community residents,give full play to the function of the community health service "six integration" and constantly raise the level of service of community health service center/station.
Objective:To investigate the awareness,utilization and satisfaction of community health center/station in more than 60 years of age residents for providing the basis in the rational allocation of health care resource.Methods:Seven hundred permanent more than 60 years of age residents in Yuhui District of Bengbu City were investigated using the self-made "community health service center/station awareness,utilization and satisfaction survey questionnaire" by the stratified cluster sampling method.Results:The 679 valid questionnaires were withdrew,the effective rate of which was 97.0%,the awareness and utilization rates of the community health service center/station were 84.1% and 58.2%,respectively.The main purposes of utilizing the community health service center/station were seeing a doctor(72.2%),prescriptions(54.2%),following-up(10.8%),medical consultation(0.3%),physiotherapy(1.0%) and listening the health knowledge lecture(4.1%).Overall satisfaction was 78.2%.Satisfaction from high to low in the order were the interpretation of the medical staff,communication and service content(82.3%),medical environment(79.5%),medical staff service attitude(78.2%),the convenient degree of seeing a doctor(76.7%),waiting or queuing time(76.5%),facilities and equipment(76.5%),medical price(65.6%) and medical cost(63.0%),whose were higher than the general and partial satisfaction of other medical institution(P<0.01).The residents proportions of worrying about infecting with disease and misdiagnosis were 14.9% and 20.8% in the treatment process,respectively,the worry degree of who was lower than that of other medical institution(P<0.01).Logistics regression analysis showed that the age and marital status,suffering from chronic diseases,trust in medical institution were important factors of satisfaction and utilizing community health service center/station(P<0.05~P<0.01).Conclusions:The awareness,utilization and satisfaction of community health service center/station in more than 60 years of age residents in Yuhui District of Bengbu City are high,but the participation rate of health knowledge lecture is low.Community health service institutions should target to carry out the work based on the characteristics of community residents,give full play to the function of the community health service "six integration" and constantly raise the level of service of community health service center/station.
2015, 40(3): 296-304.
doi: 10.13898/j.cnki.issn.1000-2200.2015.03.004
Abstract:
Objective:To investigate the chronic disease in more than 60 years of age people and analyze the influence of health related behavior.Methods:One thousand one hundred and twenty-four elder people from city and 1 157 elder people from village of Bengbu were employed using the multi-stage stratified cluster sampling method.The residents were investigated using "Health Related Behavior Questionnaire" and "Chronic Disease Questionnaire".The difference of the chronic disease of demographic-sociological point of view was analyzed using Chi-square test.The effects of demographic-sociology and health related behaviors on the chronic disease were analyzed using logistics regression analysis.Results:Two thousand and fifty-two valid questionnaires were withdrew,the effective rate of which was 90.0%,the respondents included 1 065 from city people(51.9%) and 987 from the rural community(48.1 %),1 017 man(49.6%) and 1 035 women(50.4%).The respondents age was(69.17±7.132) years old,which included 1 141 people aged 60 years more(55.6%),713 people aged 70 years more(34.7%) and 198 people aged 80 years more(9.6%).The respondents included hypertension in 887 people(43.2%),diabetes in 251 people(12.2%),chronic obstructive pulmonary disease in 268 people(13.1%),stroke in 345 people(16.8%) and other chronic diseases in 552 people(26.9%).Logistic regression analysis showed the urban community,widowhood,other marital status,smoking and frequent alcohol drinking were the risk factors of hypertension,while the moderate and light taste,physical exercise and the willingness to conduct physical examination could reduce the risk of hypertention.The urban community and smoking were the risk factors of diabetes,While physical exercise could reduce the risk of diabetes.The gender,age,widowhood,other marital status,smoking,abstaining from smoking and frequent alcohol drinking were the risk factors of chronic obstructive pulmonary disease(COPD),the living conditions and the physical exercise could reduce the resk of COPD.The urban community,widowhood,smoking and frequent alcohol drinking were the risk factors of stroke,while the living with spouse,living with children,living with spouse and children,living condition,occasional drinking,eating breakfast and physical exercise could reduce the risk of stroke.The males,widowed,other marital status,smoking and frequent alcohol drinkng were the risk factors of other chromic diseases,while the smaking cessation,accasional drinkng,moderate flavor,eating breakfast and doing exercises could reduce the risk of other chronic diseases.Conclusions:The demographic sociological factors(such as community,gender,age,marital status and living condition) and health-related behaviors(such as smoking,drinking,diet taste,physical exercises and the willingness to conduct physical examination) can affect the chronic diseases in more than 60 years of age people.
Objective:To investigate the chronic disease in more than 60 years of age people and analyze the influence of health related behavior.Methods:One thousand one hundred and twenty-four elder people from city and 1 157 elder people from village of Bengbu were employed using the multi-stage stratified cluster sampling method.The residents were investigated using "Health Related Behavior Questionnaire" and "Chronic Disease Questionnaire".The difference of the chronic disease of demographic-sociological point of view was analyzed using Chi-square test.The effects of demographic-sociology and health related behaviors on the chronic disease were analyzed using logistics regression analysis.Results:Two thousand and fifty-two valid questionnaires were withdrew,the effective rate of which was 90.0%,the respondents included 1 065 from city people(51.9%) and 987 from the rural community(48.1 %),1 017 man(49.6%) and 1 035 women(50.4%).The respondents age was(69.17±7.132) years old,which included 1 141 people aged 60 years more(55.6%),713 people aged 70 years more(34.7%) and 198 people aged 80 years more(9.6%).The respondents included hypertension in 887 people(43.2%),diabetes in 251 people(12.2%),chronic obstructive pulmonary disease in 268 people(13.1%),stroke in 345 people(16.8%) and other chronic diseases in 552 people(26.9%).Logistic regression analysis showed the urban community,widowhood,other marital status,smoking and frequent alcohol drinking were the risk factors of hypertension,while the moderate and light taste,physical exercise and the willingness to conduct physical examination could reduce the risk of hypertention.The urban community and smoking were the risk factors of diabetes,While physical exercise could reduce the risk of diabetes.The gender,age,widowhood,other marital status,smoking,abstaining from smoking and frequent alcohol drinking were the risk factors of chronic obstructive pulmonary disease(COPD),the living conditions and the physical exercise could reduce the resk of COPD.The urban community,widowhood,smoking and frequent alcohol drinking were the risk factors of stroke,while the living with spouse,living with children,living with spouse and children,living condition,occasional drinking,eating breakfast and physical exercise could reduce the risk of stroke.The males,widowed,other marital status,smoking and frequent alcohol drinkng were the risk factors of other chromic diseases,while the smaking cessation,accasional drinkng,moderate flavor,eating breakfast and doing exercises could reduce the risk of other chronic diseases.Conclusions:The demographic sociological factors(such as community,gender,age,marital status and living condition) and health-related behaviors(such as smoking,drinking,diet taste,physical exercises and the willingness to conduct physical examination) can affect the chronic diseases in more than 60 years of age people.
2015, 40(3): 305-308.
doi: 10.13898/j.cnki.issn.1000-2200.2015.03.005
Abstract:
Objective:To investigate the utilization of medical care service of residents in Anhui province,and analyze the accessibility of medical care service and its influencing factors.Methods:Three thousand and thirty-eight residents from different cities and counties in Anhui province were investigated using self-designed questionnaire "The questionnaire on New Medical Reform Policy Performance from Urban and Rural Residents'Evalution" by convenience sampling.Results:The cover rate of the basic medical insurance system in our province was up to 86.1%.The residents within 5 km distance the residence from community hospital accounted for 75%.The residents with average waiting time within half an hour accounted for 67.5%.The 86.4% of residents believed that the current medical treatment was still expensive,but it was decreased compared with before the health reform which mainly reflected in the drug price(86.1%) and technical inspection fee(86.7%).The medical and health service capacity,quality,quantity,convenience and residents' affordability have been improved.The medical expense and waiting time were decreased.Conclusions:Since the new reform of medical care has been carried out,the medical care insurance comprehensively covers,the basic medical service level improves,"the difficulty and high total cost of getting medical service" is partially resolved,and the accessibility of medical service presents a positive trend.
Objective:To investigate the utilization of medical care service of residents in Anhui province,and analyze the accessibility of medical care service and its influencing factors.Methods:Three thousand and thirty-eight residents from different cities and counties in Anhui province were investigated using self-designed questionnaire "The questionnaire on New Medical Reform Policy Performance from Urban and Rural Residents'Evalution" by convenience sampling.Results:The cover rate of the basic medical insurance system in our province was up to 86.1%.The residents within 5 km distance the residence from community hospital accounted for 75%.The residents with average waiting time within half an hour accounted for 67.5%.The 86.4% of residents believed that the current medical treatment was still expensive,but it was decreased compared with before the health reform which mainly reflected in the drug price(86.1%) and technical inspection fee(86.7%).The medical and health service capacity,quality,quantity,convenience and residents' affordability have been improved.The medical expense and waiting time were decreased.Conclusions:Since the new reform of medical care has been carried out,the medical care insurance comprehensively covers,the basic medical service level improves,"the difficulty and high total cost of getting medical service" is partially resolved,and the accessibility of medical service presents a positive trend.
2015, 40(3): 309-313.
doi: 10.13898/j.cnki.issn.1000-2200.2015.03.006
Abstract:
Objective:To investigate the effects of new health care reform policy on health equity from the resident's perspective.Methods:The health service fairness in 2 737 urban and rural residents in Anhui province were investigated by the self-designed questionnaire"the Questionnaire on New Medical Reform Policy Performance from Urban and Rural Resident's Evalution"using the convenience sampling method.Results:Among the fair indicators of health,the residents were divided into the <1 000 yuan group,1 000 to 3 000 group,>3 000 to 5 000 and >5 000 group according to their income,the two weeks prevalence rates in four groups were 36.8%,26.8%,26.8% and 22.3%,respectively.The prevalence rates of the chronic diseases in four groups were 24.6%,18.3%,17.7% and 18.3%,respectively.The differences of the two weeks prevalence rates and prevalence rates of chronic diseases in four groups were statistically significant(P<0.01),which increased with the decreasing of income.Logistic regression model showed that the age and average family income were the risk factors of two weeks prevalence rates,and the age,culture degree,marital status,average family income and payment were the risk factors of chronic illnesses.Among the equitable index of health service utilization,the visit rates in four groups were 13.1%,9.4%,10.1% and 6.9%,respectively,and the hospitalization rates of past year in four groups were 7.2%,4.5%,4.4% and 2.3%,respectively.The differences of the visit rates of two weeks and hospitalization rates in four groups were statistically significant(P<0.05).Logistic regression model showed the visit rates of two weeks increased with culture degree increasing.Among the fairness index of health financing,the own expense proportion dropped and the public expense proportion increased.Conclusions:The need of health service in different health status of urban and rural residents is different,low income families need more.Residents mainly chose villages and towns/community health service center,and the public health service demand and utilization have been improved.The health financing is unfair in a certain degree.
Objective:To investigate the effects of new health care reform policy on health equity from the resident's perspective.Methods:The health service fairness in 2 737 urban and rural residents in Anhui province were investigated by the self-designed questionnaire"the Questionnaire on New Medical Reform Policy Performance from Urban and Rural Resident's Evalution"using the convenience sampling method.Results:Among the fair indicators of health,the residents were divided into the <1 000 yuan group,1 000 to 3 000 group,>3 000 to 5 000 and >5 000 group according to their income,the two weeks prevalence rates in four groups were 36.8%,26.8%,26.8% and 22.3%,respectively.The prevalence rates of the chronic diseases in four groups were 24.6%,18.3%,17.7% and 18.3%,respectively.The differences of the two weeks prevalence rates and prevalence rates of chronic diseases in four groups were statistically significant(P<0.01),which increased with the decreasing of income.Logistic regression model showed that the age and average family income were the risk factors of two weeks prevalence rates,and the age,culture degree,marital status,average family income and payment were the risk factors of chronic illnesses.Among the equitable index of health service utilization,the visit rates in four groups were 13.1%,9.4%,10.1% and 6.9%,respectively,and the hospitalization rates of past year in four groups were 7.2%,4.5%,4.4% and 2.3%,respectively.The differences of the visit rates of two weeks and hospitalization rates in four groups were statistically significant(P<0.05).Logistic regression model showed the visit rates of two weeks increased with culture degree increasing.Among the fairness index of health financing,the own expense proportion dropped and the public expense proportion increased.Conclusions:The need of health service in different health status of urban and rural residents is different,low income families need more.Residents mainly chose villages and towns/community health service center,and the public health service demand and utilization have been improved.The health financing is unfair in a certain degree.
2015, 40(3): 314-317.
doi: 10.13898/j.cnki.issn.1000-2200.2015.03.007
Abstract:
Objective:To detect the expression of Hes1 in the development process of rat spinal cord.Methods:The rat spinal cord at embryonic day 15.5 and 18.5,the day of birth,3 days after birth,7 days,2 weeks and 4 weeks,and adult rat spinal cord were harvested,the Hes1 expressions of which were detected by the fluorescence quantitative PCR and Western blot.Results:The expressions of Hes1 in the rat spinal cord of 15.5 d to adulthood were found,which showed certain regular changes.The expressions of Hes1 in embryonic stages of rat was high,which was decreased after birth.Conclusions:The expression of Hes1 at different stages of the rat spinal cord development is different,which was high in the embryonic period,and was depressed after birth.
Objective:To detect the expression of Hes1 in the development process of rat spinal cord.Methods:The rat spinal cord at embryonic day 15.5 and 18.5,the day of birth,3 days after birth,7 days,2 weeks and 4 weeks,and adult rat spinal cord were harvested,the Hes1 expressions of which were detected by the fluorescence quantitative PCR and Western blot.Results:The expressions of Hes1 in the rat spinal cord of 15.5 d to adulthood were found,which showed certain regular changes.The expressions of Hes1 in embryonic stages of rat was high,which was decreased after birth.Conclusions:The expression of Hes1 at different stages of the rat spinal cord development is different,which was high in the embryonic period,and was depressed after birth.
2015, 40(3): 318-321.
doi: 10.13898/j.cnki.issn.1000-2200.2015.03.008
Abstract:
Objective:To construct the recombinant eukaryote expression vector containing Max interacting protein(Mxi)1-0 gene,and detect the expression of Mxi1-0 in mouse embryo fibroblast(NIH/3T3) cells for providing the basis to explore the effect and mechanism of Mxi1-0.Methods:Mxi1-0 gene was cloned by RT-PCR from cancer cells,which was subcloned into enhanced green fluorescent protein eukaryote expression vector(pEGFP-N1) to construct the recombinant vector pEGFP-N1-Mxi1-0.The recombinant vector pEGFP-N1-Mxi1-0 was identified by enzyme digestion and sequencing,which was transfected into the NIH/3T3 cells by lipidosome.The protein expression of Mxi1-0 in NIH/3T3 cells was detected by Western blot,the intracellular localization of Mxi1-0 was investigated by immunofluorescence.Results:The recombinant eukaryote expression vector encoding Mxi1-0 was successfully constructed.The expression of Mxi1-0 in NIH/3T3 cells could be detected by Western blot.The Mxi1-0 localized in the cytoplasm of NIH/3T3 cells.Conclusions:The recombinant expression vector pEGFP-N1-Mxi1-0 is successfully constructed.The Mxi1-0 expression in NIH/3T3 cells can be detected,which localizes in the cytoplasm.
Objective:To construct the recombinant eukaryote expression vector containing Max interacting protein(Mxi)1-0 gene,and detect the expression of Mxi1-0 in mouse embryo fibroblast(NIH/3T3) cells for providing the basis to explore the effect and mechanism of Mxi1-0.Methods:Mxi1-0 gene was cloned by RT-PCR from cancer cells,which was subcloned into enhanced green fluorescent protein eukaryote expression vector(pEGFP-N1) to construct the recombinant vector pEGFP-N1-Mxi1-0.The recombinant vector pEGFP-N1-Mxi1-0 was identified by enzyme digestion and sequencing,which was transfected into the NIH/3T3 cells by lipidosome.The protein expression of Mxi1-0 in NIH/3T3 cells was detected by Western blot,the intracellular localization of Mxi1-0 was investigated by immunofluorescence.Results:The recombinant eukaryote expression vector encoding Mxi1-0 was successfully constructed.The expression of Mxi1-0 in NIH/3T3 cells could be detected by Western blot.The Mxi1-0 localized in the cytoplasm of NIH/3T3 cells.Conclusions:The recombinant expression vector pEGFP-N1-Mxi1-0 is successfully constructed.The Mxi1-0 expression in NIH/3T3 cells can be detected,which localizes in the cytoplasm.
2015, 40(3): 322-325.
doi: 10.13898/j.cnki.issn.1000-2200.2015.03.009
Abstract:
Objective:To investigate the effects of linear alkylbenzenesulfonate(LAS) om the oxidative stress damage of mouse skin and antagonism of isoflavone.Methods:Forty healthy male Kunming mice were randomly divided into the control group,low-dosage LAS group(150 mg/L),middle-dosage LAS group(300 mg/L) and high-dosage LAS group(600 mg/L)(10 mice each group).The distilled water and different dosage LAS were smeared on the back skin of mice once a day for 60 days.Fifty mice were randomly divided into the control group,LAS oxidative stress damage model group(skin smeared with 300 mg/L of LAS) and three antagonistic groups(skin smeared with 300 mg/L LAS after smearing 50,100 and 150 mg/L of isoflavone,once a day for 60 days).The content of malondialdehyde(MDA)and activities of super oxidase dimutase(SOD) and glutathione peroxidase(GSH-Px) in all mice skin were detected.Results:The content of MDA in mice skin smeared with LAS was remarkably higher than that in control group(P<0.01),and the contents of MDA in high-dosage LAS group were significantly higher than that in low- and middle-dosage LAS groups(P<0.01).The activities of SOD and GSH-Px in middle- and high- dosage LAS group were obviously lower than those in control group(P<0.01),which decreased with the dosage increasing of LAS(P<0.01).After isoflavone intervention,the contents of MDA in all antagonistic groups were lower than that in LAS damage group,and higher than that in control group(P<0.05 to P<0.01).Except the antagonistic group 1,the differences of the GSH-Px activity between other antagonistic groups and LAS damage groups were not statistically significant(P>0.05),the activities of SOD and GSH-Px in antagonistic groups were higher than those in LAS damage groups,and lower than those in control group(P<0.05 to P<0.01).The antagonistic effects increased with the isoflavone concentration increasing.Conclusions:LAS can lead to the oxidative stree damage of mouse skin,and the isoflavone can restrain the damage within a certain range of dosage.
Objective:To investigate the effects of linear alkylbenzenesulfonate(LAS) om the oxidative stress damage of mouse skin and antagonism of isoflavone.Methods:Forty healthy male Kunming mice were randomly divided into the control group,low-dosage LAS group(150 mg/L),middle-dosage LAS group(300 mg/L) and high-dosage LAS group(600 mg/L)(10 mice each group).The distilled water and different dosage LAS were smeared on the back skin of mice once a day for 60 days.Fifty mice were randomly divided into the control group,LAS oxidative stress damage model group(skin smeared with 300 mg/L of LAS) and three antagonistic groups(skin smeared with 300 mg/L LAS after smearing 50,100 and 150 mg/L of isoflavone,once a day for 60 days).The content of malondialdehyde(MDA)and activities of super oxidase dimutase(SOD) and glutathione peroxidase(GSH-Px) in all mice skin were detected.Results:The content of MDA in mice skin smeared with LAS was remarkably higher than that in control group(P<0.01),and the contents of MDA in high-dosage LAS group were significantly higher than that in low- and middle-dosage LAS groups(P<0.01).The activities of SOD and GSH-Px in middle- and high- dosage LAS group were obviously lower than those in control group(P<0.01),which decreased with the dosage increasing of LAS(P<0.01).After isoflavone intervention,the contents of MDA in all antagonistic groups were lower than that in LAS damage group,and higher than that in control group(P<0.05 to P<0.01).Except the antagonistic group 1,the differences of the GSH-Px activity between other antagonistic groups and LAS damage groups were not statistically significant(P>0.05),the activities of SOD and GSH-Px in antagonistic groups were higher than those in LAS damage groups,and lower than those in control group(P<0.05 to P<0.01).The antagonistic effects increased with the isoflavone concentration increasing.Conclusions:LAS can lead to the oxidative stree damage of mouse skin,and the isoflavone can restrain the damage within a certain range of dosage.
2015, 40(3): 326-329.
doi: 10.13898/j.cnki.issn.1000-2200.2015.03.010
Abstract:
Objective:To investigate the best time of enteral nutrition(EN),and observe the effects of early enteral nutrition(EEN) on intestinal mucosa damage after burn injury.Methods:Rats were inflicted with 30% total body surface area full-thickness burn.Eighty-eight Wistar rats were randomly divided into the sham burn control group(C group),early enteral nutrition group(EEN group,in which enteral nutrition was given at the sixth hour after burn) and delayed enteral nutrition group(DEN group,in which enteral nutrition began at the 24th hour after burn).The intestinal mucosal potential difference(PD),intestinal mucosal blood flow(IMBF),jejunum pH(pHi),level of plasma lipopolysaccharide(LPS),diamine oxidase(DAO) activity and intestinal mucosa damage index in all rats were detected before burn and at postburn 0.5,1,3,7 and 10 days(PBD).Results:After burn injury,compared with C group,the levels of PD,IMBF and pHi in burned rats were markedly decreased(P<0.01),while the LPS content,DAO activity and mucosa damage index were significantly increased(P<0.05 to P<0.01).Compared with DEN group,the PD and IMBF at PBD 1 to 10 and pHi at PBD 1,PBD 3,PBD 10 in EEN group were significantly high(P<0.05 to P<0.01),but the LPS content at PBD 3 to 10 and DAO activity at PBD 3 were obviously low in EEN group(P<0.01).No apparent discomfort,such as vomit,abdominal distension and diarrhea in two groups were found.Conclusions:Early enteral nutrition can improve the intestinal mucosal blood flow,reduce the intestinal damage,and maintain the structure and function of intestinal mucosa after burn injury.
Objective:To investigate the best time of enteral nutrition(EN),and observe the effects of early enteral nutrition(EEN) on intestinal mucosa damage after burn injury.Methods:Rats were inflicted with 30% total body surface area full-thickness burn.Eighty-eight Wistar rats were randomly divided into the sham burn control group(C group),early enteral nutrition group(EEN group,in which enteral nutrition was given at the sixth hour after burn) and delayed enteral nutrition group(DEN group,in which enteral nutrition began at the 24th hour after burn).The intestinal mucosal potential difference(PD),intestinal mucosal blood flow(IMBF),jejunum pH(pHi),level of plasma lipopolysaccharide(LPS),diamine oxidase(DAO) activity and intestinal mucosa damage index in all rats were detected before burn and at postburn 0.5,1,3,7 and 10 days(PBD).Results:After burn injury,compared with C group,the levels of PD,IMBF and pHi in burned rats were markedly decreased(P<0.01),while the LPS content,DAO activity and mucosa damage index were significantly increased(P<0.05 to P<0.01).Compared with DEN group,the PD and IMBF at PBD 1 to 10 and pHi at PBD 1,PBD 3,PBD 10 in EEN group were significantly high(P<0.05 to P<0.01),but the LPS content at PBD 3 to 10 and DAO activity at PBD 3 were obviously low in EEN group(P<0.01).No apparent discomfort,such as vomit,abdominal distension and diarrhea in two groups were found.Conclusions:Early enteral nutrition can improve the intestinal mucosal blood flow,reduce the intestinal damage,and maintain the structure and function of intestinal mucosa after burn injury.
2015, 40(3): 330-333.
doi: 10.13898/j.cnki.issn.1000-2200.2015.03.011
Abstract:
Objective:To investigate the effects of catalase(CAT),superoxide dismutase(SOD) and glutathione system on the coronary heart disease of different age patients.Methods:One hundred and seventy-nine 49 to 90 years old patients with coronary heart disease were divided into the non-senile group(77 cases,less than 60 years old) and senile group(102 cases,more than or equal to 60 years old).The levels of fasting lipid,fasting glucose,CAT,SOD,GSH,GSH-Px and GR,height and weight in all cases were measured.The results of coronary arteriography of all cases were assessed using Gensini score system.Results:The serum levels of GSH,GSH-Px,GR,CAT and SOD in senile group were lower than those in non-senile group(P<0.05 to P<0.01).There was significantly negative correlation between the levels of GSH,GSH-Px,GR,CAT and SOD,and Gensini scores after righting age(P<0.01).The results of multiple linear regression analysis showed that the effects of GSH-Px and CAT on Gensini scores were great.Conclusions:The levels of GSH,GSH-PX,GR,CAT and SOD significantly decrease with the growth of age,which is negative correlation with coronary artery disease.The effects of GSH-Px and CAT on coronary artery disease are great.
Objective:To investigate the effects of catalase(CAT),superoxide dismutase(SOD) and glutathione system on the coronary heart disease of different age patients.Methods:One hundred and seventy-nine 49 to 90 years old patients with coronary heart disease were divided into the non-senile group(77 cases,less than 60 years old) and senile group(102 cases,more than or equal to 60 years old).The levels of fasting lipid,fasting glucose,CAT,SOD,GSH,GSH-Px and GR,height and weight in all cases were measured.The results of coronary arteriography of all cases were assessed using Gensini score system.Results:The serum levels of GSH,GSH-Px,GR,CAT and SOD in senile group were lower than those in non-senile group(P<0.05 to P<0.01).There was significantly negative correlation between the levels of GSH,GSH-Px,GR,CAT and SOD,and Gensini scores after righting age(P<0.01).The results of multiple linear regression analysis showed that the effects of GSH-Px and CAT on Gensini scores were great.Conclusions:The levels of GSH,GSH-PX,GR,CAT and SOD significantly decrease with the growth of age,which is negative correlation with coronary artery disease.The effects of GSH-Px and CAT on coronary artery disease are great.
2015, 40(3): 334-335.
doi: 10.13898/j.cnki.issn.1000-2200.2015.03.012
Abstract:
Objective:To investigate the therapeutic effect of improved triangular flap in repairing the unilateral incomplete cleft lip.Methods:Twenty-five patients with unilateral incomplete cleft lip were treated with the improved triangular flap.The contralateral philtrum ridge acted as a reference in fixing the surgery point;the nasal alar basal muscles were separated,a complete orbicularis oris muscle ring was reconstructed and the two sides of the lip were kept at the same height.Results:The operation was successful in all the cases.The nostrils were in symmetry,the scars were at the philtrum ridge,the labial archs in good shape and the rosylips well-stacked.All the twenty-five patients were satisfied with the results.Conclusions:The improved triangular flap may present a symmetrical nasolabial region and natural shape.It is an effective procedure for repair of the unilateral incomplete cleft lip
Objective:To investigate the therapeutic effect of improved triangular flap in repairing the unilateral incomplete cleft lip.Methods:Twenty-five patients with unilateral incomplete cleft lip were treated with the improved triangular flap.The contralateral philtrum ridge acted as a reference in fixing the surgery point;the nasal alar basal muscles were separated,a complete orbicularis oris muscle ring was reconstructed and the two sides of the lip were kept at the same height.Results:The operation was successful in all the cases.The nostrils were in symmetry,the scars were at the philtrum ridge,the labial archs in good shape and the rosylips well-stacked.All the twenty-five patients were satisfied with the results.Conclusions:The improved triangular flap may present a symmetrical nasolabial region and natural shape.It is an effective procedure for repair of the unilateral incomplete cleft lip
2015, 40(3): 336-338.
doi: 10.13898/j.cnki.issn.1000-2200.2015.03.013
Abstract:
Objective:To investigate the effects of kinesitherapy on the muscle tension and gait of patients with Parkinson's disease(PD).Methods:Thirty-six patients with Parkinson's disease were randomly divided into the experiment group(18 cases) and control group(18 cases).The basic drug treatment of two groups were the same,and the experiment group were additionally treated with kinesitherapy.The differences of the modified Ashworth score,walking speed,cycle time and repeat step distance on foot between two groups were analyzed before and after treatment.Results:Compared with the control group,the modified Ashworth score,walking speed,cycle time and repeat step distance on foot in experiment group after treatment decreased,sped,shortened and increased,respectively(P<0.01).Conclusions:The kinesitherapy can reduce the muscle tension,increase the pace and improve the symptoms of gait.
Objective:To investigate the effects of kinesitherapy on the muscle tension and gait of patients with Parkinson's disease(PD).Methods:Thirty-six patients with Parkinson's disease were randomly divided into the experiment group(18 cases) and control group(18 cases).The basic drug treatment of two groups were the same,and the experiment group were additionally treated with kinesitherapy.The differences of the modified Ashworth score,walking speed,cycle time and repeat step distance on foot between two groups were analyzed before and after treatment.Results:Compared with the control group,the modified Ashworth score,walking speed,cycle time and repeat step distance on foot in experiment group after treatment decreased,sped,shortened and increased,respectively(P<0.01).Conclusions:The kinesitherapy can reduce the muscle tension,increase the pace and improve the symptoms of gait.
2015, 40(3): 339-341.
doi: 10.13898/j.cnki.issn.1000-2200.2015.03.014
Abstract:
Objective:To explore the management skills of ureteroscope and handling the accidents strategy.Methods:The clinical data of 956 patients with ureteral calculi treated with Holmium laser lithotripsy under ureteroscope were retrospectively analyzed.Results:The ureteroscope operations in 103 cases were difficulty,which included 56 cases with ureterostenosis(including the ureter opening stricture in 16 cases,mild ureteral stenosis in 26 cases,segment ureteral stricture in 5 cases and ureteral stricture ring in 9 cases),35 cases with ureter twist,4 cases with the opening blocked by ureter stone,2 cases with no ureter opening because of cystitis(pelvic lipomatosis),2 cases with ureteropelvic atresia,2 cases with prostatic hyperplasia complicated with more prostate tissue breaking into the bladder,1 case with renal pelvis perforation caused by placing double J tube and 1 case with open surgery because of the placing double J tube failure.Conclusions:The ureteral stenosis and distortion are usually problems in ureteroscope operation,which can be settled by guiding catheter dilatation,increasing water pressure,changing position,replacing fine ureteroscope and exchanging the angle of ureteroscope.open surgery is the effective measure to correct error.
Objective:To explore the management skills of ureteroscope and handling the accidents strategy.Methods:The clinical data of 956 patients with ureteral calculi treated with Holmium laser lithotripsy under ureteroscope were retrospectively analyzed.Results:The ureteroscope operations in 103 cases were difficulty,which included 56 cases with ureterostenosis(including the ureter opening stricture in 16 cases,mild ureteral stenosis in 26 cases,segment ureteral stricture in 5 cases and ureteral stricture ring in 9 cases),35 cases with ureter twist,4 cases with the opening blocked by ureter stone,2 cases with no ureter opening because of cystitis(pelvic lipomatosis),2 cases with ureteropelvic atresia,2 cases with prostatic hyperplasia complicated with more prostate tissue breaking into the bladder,1 case with renal pelvis perforation caused by placing double J tube and 1 case with open surgery because of the placing double J tube failure.Conclusions:The ureteral stenosis and distortion are usually problems in ureteroscope operation,which can be settled by guiding catheter dilatation,increasing water pressure,changing position,replacing fine ureteroscope and exchanging the angle of ureteroscope.open surgery is the effective measure to correct error.
2015, 40(3): 342-344.
doi: 10.13898/j.cnki.issn.1000-2200.2015.03.015
Abstract:
Objective:To investigate the clinical effects of microsurgery in treating the rupturing anterior communicating artery aneurysm.Methods:The clinical data of 23 cases with rupturing anterior communicating artery aneurysm were retrospectively analyzed.Sixteen cases were treated with Yasargil pterional approach,7 cases were treated with supraorbital keyhole approach.Results:According to the Glasgow Outcome Score,18 patients(78.3%) were complete recovery,1 case(4.3%) was moderate disability,2 cases(8.7%) were severe disability and 2 cases(8.7%) died.All patients were followed up for 6 to 12 months.No incomplete or false clipping vessel were observed by the postoperative CTA.Conclusions:The pterional approach and supraorbital keyhole approach,which can fully expose the aneurysms,is an effective method in treating anterior communicating artery aneurysms in the patients with grade Ⅰto Ⅲ of Hunt-Hess rupture.
Objective:To investigate the clinical effects of microsurgery in treating the rupturing anterior communicating artery aneurysm.Methods:The clinical data of 23 cases with rupturing anterior communicating artery aneurysm were retrospectively analyzed.Sixteen cases were treated with Yasargil pterional approach,7 cases were treated with supraorbital keyhole approach.Results:According to the Glasgow Outcome Score,18 patients(78.3%) were complete recovery,1 case(4.3%) was moderate disability,2 cases(8.7%) were severe disability and 2 cases(8.7%) died.All patients were followed up for 6 to 12 months.No incomplete or false clipping vessel were observed by the postoperative CTA.Conclusions:The pterional approach and supraorbital keyhole approach,which can fully expose the aneurysms,is an effective method in treating anterior communicating artery aneurysms in the patients with grade Ⅰto Ⅲ of Hunt-Hess rupture.
2015, 40(3): 345-347.
doi: 10.13898/j.cnki.issn.1000-2200.2015.03.016
Abstract:
Objective:To explore the clinical effects of sternocleidomastoid flap combined with amorphous decellularized dermal matrix(ADM) medical organization patch in the prevention of Frey syndrome after partial parotidectomy.Methods:One hundred and three patients with parotid benign tumor were randomly divided into the experiment group A and B(35 cases each group) and group C(33 cases).Group A and B were treated with sternocleidomastoid flap and sternocleidomastoid flap combined with ADM,respectively.The wounds in group C were directly closed without any repair.All patients were followed up for 6 to 42 months.The positive cases of iodine-starch test and subjective evaluation in 3 groups were observed in 6 months after operation.Results:The positive rates of iodine-starch test and subjective evaluation in group A and C were higher than those in group B(P<0.01),the positive rates of iodine-starch test and subjective evaluation in group C were higher than those in group A(P<0.01).Conclusions:The effect of sternocleidomastoid flap in the prevention of Frey syndrome after parotidectomy is good,but the preventive effect of sternocleidomastoid flap combined with ADM is better.
Objective:To explore the clinical effects of sternocleidomastoid flap combined with amorphous decellularized dermal matrix(ADM) medical organization patch in the prevention of Frey syndrome after partial parotidectomy.Methods:One hundred and three patients with parotid benign tumor were randomly divided into the experiment group A and B(35 cases each group) and group C(33 cases).Group A and B were treated with sternocleidomastoid flap and sternocleidomastoid flap combined with ADM,respectively.The wounds in group C were directly closed without any repair.All patients were followed up for 6 to 42 months.The positive cases of iodine-starch test and subjective evaluation in 3 groups were observed in 6 months after operation.Results:The positive rates of iodine-starch test and subjective evaluation in group A and C were higher than those in group B(P<0.01),the positive rates of iodine-starch test and subjective evaluation in group C were higher than those in group A(P<0.01).Conclusions:The effect of sternocleidomastoid flap in the prevention of Frey syndrome after parotidectomy is good,but the preventive effect of sternocleidomastoid flap combined with ADM is better.
2015, 40(3): 348-350.
doi: 10.13898/j.cnki.issn.1000-2200.2015.03.017
Abstract:
Objective:To investigate the prediction value of peripheral blood procalcitonin(PCT) levels in the prognosis evaluation of patients with heart failure with preserved ejection fraction(HFPEF).Methods:One hundred and twenty-five patients with HFPEF were enrolled.Serum PCT levels were monitored,and the acute physiology and chronic health evaluation Ⅱ(APACHE Ⅱ) score,sequential organ failure assessment(SOFA) score were recorded at the 1st,2nd,3rd and 5th day.According to the 14-day outcome after admission,the patients with HFPEF were divided into survivor group and non-survivor group,the dynamic changes of serum PCT levels,APACHE Ⅱ score and SOFA score were compared between the two groups and the correlation analysis was carried out.Results:There was no significant difference in serum PCT levels at the 1st and 2nd day between survivor group and non-survivor group(P >0.05),but the positive statistical correlation was found between serum PCT levels and APACHE Ⅱ score,SOFA score in non-survivor group(P<0.01).Receiver operator characteristic curve revealed serum PCT levels on the 3rd day could significantly predict the 14-day mortality,maximal area under the curve of serum PCT was 0.815.Conclusions:Dynamic monitoring of serum PCT levels could help to assessment the prognosis of patients with HFPEF,also to predict the severity of the illness.
Objective:To investigate the prediction value of peripheral blood procalcitonin(PCT) levels in the prognosis evaluation of patients with heart failure with preserved ejection fraction(HFPEF).Methods:One hundred and twenty-five patients with HFPEF were enrolled.Serum PCT levels were monitored,and the acute physiology and chronic health evaluation Ⅱ(APACHE Ⅱ) score,sequential organ failure assessment(SOFA) score were recorded at the 1st,2nd,3rd and 5th day.According to the 14-day outcome after admission,the patients with HFPEF were divided into survivor group and non-survivor group,the dynamic changes of serum PCT levels,APACHE Ⅱ score and SOFA score were compared between the two groups and the correlation analysis was carried out.Results:There was no significant difference in serum PCT levels at the 1st and 2nd day between survivor group and non-survivor group(P >0.05),but the positive statistical correlation was found between serum PCT levels and APACHE Ⅱ score,SOFA score in non-survivor group(P<0.01).Receiver operator characteristic curve revealed serum PCT levels on the 3rd day could significantly predict the 14-day mortality,maximal area under the curve of serum PCT was 0.815.Conclusions:Dynamic monitoring of serum PCT levels could help to assessment the prognosis of patients with HFPEF,also to predict the severity of the illness.
2015, 40(3): 351-353.
doi: 10.13898/j.cnki.issn.1000-2200.2015.03.018
Abstract:
Objective:To investigate the clinical effects of continuous femoral nerve block guided by ultrasound on the postoperative rehabilitation analgesia in elderly patients with total knee arthroplasty.Methods:Sixty elderly patients with ASA Ⅰ-Ⅲ treated with unilateral total knee arthroplasty were randomly divided into the intravenous analgesia group(group A) and continuous femoral nerve block analgesia guided by ultrasound group(group B)(30 cases each group).The pain visual analogue scale of resting and continuous passive motion,strength rating and incidence of adverse reaction in two groups were observed.Results:The pain visual analogue scale of resting and continuous passive motion of group B after operation were significantly lower than those of group A(P<0.01).Conclusions:The clinical effect of continuous femoral nerve block guided by ultrasound on the postoperative analgesia in elderly patients with total knee arthroplasty is good,which is a good method of easing pain after operation.
Objective:To investigate the clinical effects of continuous femoral nerve block guided by ultrasound on the postoperative rehabilitation analgesia in elderly patients with total knee arthroplasty.Methods:Sixty elderly patients with ASA Ⅰ-Ⅲ treated with unilateral total knee arthroplasty were randomly divided into the intravenous analgesia group(group A) and continuous femoral nerve block analgesia guided by ultrasound group(group B)(30 cases each group).The pain visual analogue scale of resting and continuous passive motion,strength rating and incidence of adverse reaction in two groups were observed.Results:The pain visual analogue scale of resting and continuous passive motion of group B after operation were significantly lower than those of group A(P<0.01).Conclusions:The clinical effect of continuous femoral nerve block guided by ultrasound on the postoperative analgesia in elderly patients with total knee arthroplasty is good,which is a good method of easing pain after operation.
2015, 40(3): 354-356.
doi: 10.13898/j.cnki.issn.1000-2200.2015.03.019
Abstract:
Objective:To evaluate the therapeutic efficacy and safety of different diameters of endoscopic papillary balloon dilation(EPBD) for removing common bile duct(CBD) stones.Methods:Patients with CBD stones were divided into 5 groups according to the maximum diameter of stone(≤5 mm,>5~8 mm,>8～<12 mm、12~<14 mm and ≥14 mm),and treated with single limited endoscopic sphincterotomy(EST) and limited EST combined with EPBD with diameter of 8 mm,10 mm,12 mm,and 14 mm balloons,respectively.The postoperative complications in all groups were observed.Results:The success rate of removing stone was 100% in each group.Except the difference of pneumobilia,the differences of other complications between short-and long-term in all groups were not statistically different(P>0.05).Conclusions:Choosing suitable balloon size for dilation according the diameter of stone combined with limited EST to remove CBD stone is safe and effective.Choosing the balloon diameter more than 15 mm needs to be cautious.
Objective:To evaluate the therapeutic efficacy and safety of different diameters of endoscopic papillary balloon dilation(EPBD) for removing common bile duct(CBD) stones.Methods:Patients with CBD stones were divided into 5 groups according to the maximum diameter of stone(≤5 mm,>5~8 mm,>8～<12 mm、12~<14 mm and ≥14 mm),and treated with single limited endoscopic sphincterotomy(EST) and limited EST combined with EPBD with diameter of 8 mm,10 mm,12 mm,and 14 mm balloons,respectively.The postoperative complications in all groups were observed.Results:The success rate of removing stone was 100% in each group.Except the difference of pneumobilia,the differences of other complications between short-and long-term in all groups were not statistically different(P>0.05).Conclusions:Choosing suitable balloon size for dilation according the diameter of stone combined with limited EST to remove CBD stone is safe and effective.Choosing the balloon diameter more than 15 mm needs to be cautious.
2015, 40(3): 357-358,361.
doi: 10.13898/j.cnki.issn.1000-2200.2015.03.020
Abstract:
Objective:To investigate the effects of recombinant human growth hormone(r-hGH) combined with branched chain amino acid(BCAA) on the levels of Tumor necrosis factor-α(TNF-α) and interleukins-10(IL-10) in patients with decompensated cirrhosis.Methods:Eighty-two patients with decompensated cirrhosis were randomly divided into the treatment group(42 cases) and control group(40 cases).The treatment group and control group were treated with 5 IU of r-hGH by subcutaneous injection 1 time two days combined with 250 ml of BCAA by intravenous drip once a day for 20 d and 250 ml of BCAA by intravenous drip once a day for 20 d based on protecting liver and support treatment,respectively.The liver function and levels of TNF-α and IL-10 in two groups were observed before and after treatment.Results:The liver function and levels of TNF-α and IL-10 in two groups were improved,the improvement of poor appetite,lower limbs edema,and the levels of alanine aminotransferase,albumin,TNF-α and IL-10 in treatment group were better than those in control group(P<0.05 to P<0.01).Conclusions:The effects of r-hGH combined with BCAA on the improvement of serum albumin,TNF-α and IL-10 levels are better than those of BCAA alone.
Objective:To investigate the effects of recombinant human growth hormone(r-hGH) combined with branched chain amino acid(BCAA) on the levels of Tumor necrosis factor-α(TNF-α) and interleukins-10(IL-10) in patients with decompensated cirrhosis.Methods:Eighty-two patients with decompensated cirrhosis were randomly divided into the treatment group(42 cases) and control group(40 cases).The treatment group and control group were treated with 5 IU of r-hGH by subcutaneous injection 1 time two days combined with 250 ml of BCAA by intravenous drip once a day for 20 d and 250 ml of BCAA by intravenous drip once a day for 20 d based on protecting liver and support treatment,respectively.The liver function and levels of TNF-α and IL-10 in two groups were observed before and after treatment.Results:The liver function and levels of TNF-α and IL-10 in two groups were improved,the improvement of poor appetite,lower limbs edema,and the levels of alanine aminotransferase,albumin,TNF-α and IL-10 in treatment group were better than those in control group(P<0.05 to P<0.01).Conclusions:The effects of r-hGH combined with BCAA on the improvement of serum albumin,TNF-α and IL-10 levels are better than those of BCAA alone.
2015, 40(3): 359-361.
doi: 10.13898/j.cnki.issn.1000-2200.2015.03.021
Abstract:
Objective:To investigate the clinical effects of cannulated screw combined with support plate in the treatment of Hoffa fracture.Methods:Nine patients with Hoffa fractures were treated with open reduction,anterior-to-posterior cannulated screw combined with support plate fixation.Type Ⅰ in 5 cases,type Ⅱ in 2 cases and type Ⅲ in 2 cases were observed in 5 males and 1 female according to Letenneur classification.Supracondylar fracture in 2 cases and supracondylar complicated with intercondylar fracture in 3 cases were found.The postoperative function of knee joint was evaluated according to the Letenneur knee function evaluation system.Results:All patients were followed up for 3 to 24 months.All incisions were primary healing without early complication.The interfixation loosing and rupture,fracture nonunion and avascular necrosis of femoral condyle were not found after operation.The time fracture healing was 8 to 12 weeks.The functional recovery of 7 cases and 2 cases were excellent and good according to Hoffa evaluation system,respectively.Conclusions:The theraputic effects of cannulated screw combined with support plate on Hoffa fracture are reliable and good,the patients can do early functional exercise.
Objective:To investigate the clinical effects of cannulated screw combined with support plate in the treatment of Hoffa fracture.Methods:Nine patients with Hoffa fractures were treated with open reduction,anterior-to-posterior cannulated screw combined with support plate fixation.Type Ⅰ in 5 cases,type Ⅱ in 2 cases and type Ⅲ in 2 cases were observed in 5 males and 1 female according to Letenneur classification.Supracondylar fracture in 2 cases and supracondylar complicated with intercondylar fracture in 3 cases were found.The postoperative function of knee joint was evaluated according to the Letenneur knee function evaluation system.Results:All patients were followed up for 3 to 24 months.All incisions were primary healing without early complication.The interfixation loosing and rupture,fracture nonunion and avascular necrosis of femoral condyle were not found after operation.The time fracture healing was 8 to 12 weeks.The functional recovery of 7 cases and 2 cases were excellent and good according to Hoffa evaluation system,respectively.Conclusions:The theraputic effects of cannulated screw combined with support plate on Hoffa fracture are reliable and good,the patients can do early functional exercise.
2015, 40(3): 362-363,366.
doi: 10.13898/j.cnki.issn.1000-2200.2015.03.022
Abstract:
Objective:To explore the curative effects of double frontal decompressive craniectomy through coronal incision in the treatment of severe bifrontal contusion.Methods:The data of 21 patients with severe bifrontal contusion treated with double frontal decompressive craniectomy through coronal incision and without retaining frontal bone bridge were retrospectively analyzed.Results:All patients were followed up for 1 year.Nineteen cases survived,2 cases died.Excellent in 11 cases(52.3%),light disability in 5 cases(23.8%),heavy disability in 3 cases(14.2%) and death in 2 cases(9.5%) were found according to the Clasgow outcome scale.Conclusions:The curative effects of double frontal decompressive craniectomy through coronal incision in treating severe bifrontal contusion are good,which can effectively improve the prognosis,and reduce disability and mortality of patients.
Objective:To explore the curative effects of double frontal decompressive craniectomy through coronal incision in the treatment of severe bifrontal contusion.Methods:The data of 21 patients with severe bifrontal contusion treated with double frontal decompressive craniectomy through coronal incision and without retaining frontal bone bridge were retrospectively analyzed.Results:All patients were followed up for 1 year.Nineteen cases survived,2 cases died.Excellent in 11 cases(52.3%),light disability in 5 cases(23.8%),heavy disability in 3 cases(14.2%) and death in 2 cases(9.5%) were found according to the Clasgow outcome scale.Conclusions:The curative effects of double frontal decompressive craniectomy through coronal incision in treating severe bifrontal contusion are good,which can effectively improve the prognosis,and reduce disability and mortality of patients.
2015, 40(3): 364-366.
doi: 10.13898/j.cnki.issn.1000-2200.2015.03.023
Abstract:
Objective:To investigate the application value of trans-vaginal and trans-abdominal hysterectomy(TVH and TAH)in non-prolapsed uterus disease.Methods:The data of 80 patients with non-prolapsed uterus(benign lesions) treated with hysterectomy were retrospectively analyzed,which included 26 cases treated with TVH and 54 cases treated with TAH.The time of operation,hospitalization,anus exhaust,ambulation and postoperative temperature recovery,blood loss and postoperative analgesia rate and infection between two groups were compared.Results:All operations in two groups were successful.Compared with patients treated with TAH,the shortertime of operation,hospitalization,anus exhaust,ambulation and post-operative temperature recovery,less blood loss and lighter postoperative pain were observed in patients treated with TVH(P<0.01).Conclusions:TVH significantly improves the life quality of patients withnon-prolapsed uterus disease,which is safe,feasibleand ideal surgery.
Objective:To investigate the application value of trans-vaginal and trans-abdominal hysterectomy(TVH and TAH)in non-prolapsed uterus disease.Methods:The data of 80 patients with non-prolapsed uterus(benign lesions) treated with hysterectomy were retrospectively analyzed,which included 26 cases treated with TVH and 54 cases treated with TAH.The time of operation,hospitalization,anus exhaust,ambulation and postoperative temperature recovery,blood loss and postoperative analgesia rate and infection between two groups were compared.Results:All operations in two groups were successful.Compared with patients treated with TAH,the shortertime of operation,hospitalization,anus exhaust,ambulation and post-operative temperature recovery,less blood loss and lighter postoperative pain were observed in patients treated with TVH(P<0.01).Conclusions:TVH significantly improves the life quality of patients withnon-prolapsed uterus disease,which is safe,feasibleand ideal surgery.
2015, 40(3): 367-368.
doi: 10.13898/j.cnki.issn.1000-2200.2015.03.024
Abstract:
Objective:To investigate the pathologic features of endometrium in perimenopausal women with abnormal uterine bleeding.Methods:The pathologic data of endometrium in 152 perimenopausal women with abnormal uterine bleeding were retrospectively analyzed.Results:Among 152 cases,the hyperplasis endometria in 74 cases(48.68%),proliferated phase of endometria in 48 cases(31.58%),secretory endometria in 18 cases(11.84%),hormone therapy endometria in 2 cases(1.32%),endometrial polyps in 7 cases(4.61%),local endometrial cancer in 1 case(0.66%) and incomplete abortion in 2 cases(1.32%) were identified.Conclusions:Hyperplasis is the most common cause of the abnormal uterine bleeding in perimenopausal women,thereby the pathological diagnosis of endometrium should be noted.
Objective:To investigate the pathologic features of endometrium in perimenopausal women with abnormal uterine bleeding.Methods:The pathologic data of endometrium in 152 perimenopausal women with abnormal uterine bleeding were retrospectively analyzed.Results:Among 152 cases,the hyperplasis endometria in 74 cases(48.68%),proliferated phase of endometria in 48 cases(31.58%),secretory endometria in 18 cases(11.84%),hormone therapy endometria in 2 cases(1.32%),endometrial polyps in 7 cases(4.61%),local endometrial cancer in 1 case(0.66%) and incomplete abortion in 2 cases(1.32%) were identified.Conclusions:Hyperplasis is the most common cause of the abnormal uterine bleeding in perimenopausal women,thereby the pathological diagnosis of endometrium should be noted.
2015, 40(3): 369-371.
doi: 10.13898/j.cnki.issn.1000-2200.2015.03.025
Abstract:
Objective:To investigate the effects of early minimally invasive puncture drainage in the treatment of mediumandminimum basal ganglia hemorrhage caused by hypertension,and provide theoretical basis for its clinical treatment.Methods:Sixty-eight patients with basal ganglia hemorrhage caused by hypertension were divided into the control group and study group(34 cases each group) according to the order of admission.The control group and study group were treated with conservative treatment and early minimally invasive puncture drainage based on the conservative treatment,respectively.The hematoma and cerebral edema volume and neurological function scores between two groups were compared after 3 and 14 days of treatment,the abilities of daily life between two groups were analyzed after 3 months of treatment.Results:Compared with the control group,the hematoma and edema volume and neurological deficit scores in study group decreased significantly after 3 and 14 days of treatment(P<0.01),the total effective rate of independent living and mildly dependent in study group(73.53%) was significantly higher than that in control group(44.12%) after 3 months of treatment(P<0.05).Conclusions:The treatment of medium and minimum basal ganglia hemorrhage caused by hypertension with minimally invasive puncture drainage is safe and reliable,which should be widely applied.
Objective:To investigate the effects of early minimally invasive puncture drainage in the treatment of mediumandminimum basal ganglia hemorrhage caused by hypertension,and provide theoretical basis for its clinical treatment.Methods:Sixty-eight patients with basal ganglia hemorrhage caused by hypertension were divided into the control group and study group(34 cases each group) according to the order of admission.The control group and study group were treated with conservative treatment and early minimally invasive puncture drainage based on the conservative treatment,respectively.The hematoma and cerebral edema volume and neurological function scores between two groups were compared after 3 and 14 days of treatment,the abilities of daily life between two groups were analyzed after 3 months of treatment.Results:Compared with the control group,the hematoma and edema volume and neurological deficit scores in study group decreased significantly after 3 and 14 days of treatment(P<0.01),the total effective rate of independent living and mildly dependent in study group(73.53%) was significantly higher than that in control group(44.12%) after 3 months of treatment(P<0.05).Conclusions:The treatment of medium and minimum basal ganglia hemorrhage caused by hypertension with minimally invasive puncture drainage is safe and reliable,which should be widely applied.
2015, 40(3): 372-374.
doi: 10.13898/j.cnki.issn.1000-2200.2015.03.026
Abstract:
Objective:To analyze the influence factors of symptom-to-balloon time during percutaneous coronary intervention(PCI) in myocardial infarction patients with ST-segment elevation.Methods:Data of 47 patients with ST-segment elevation myocardial infarction who received primary PCI during October 2012 to February 2014 were analyzed.All these patients were divided into group A(attributed the symptoms to angina pectoris) and group B(not attributed the symptoms to angina pectoris);group C(clinical pathway group) and D group(not clinical pathway group).The symptoms to visit time,whether to use the emergency service system,communication time,communication to signature time,clinic to balloon time,PCI operation time,transfer to catheter room time were compared between group A and B;the time for communication,communication to signature time,clinic to balloon time,PCI operation time,transfer to catheter room time were compared between group C and D.Results:Compared with group B,the symptoms to treatment time,door to balloon time in group A were shortened(P<0.01 and P<0.05),the proportion of admission through emergency service system were higher(P<0.01),no differences between the communication to signature time and PCI time(P>0.05).Compared with group D,in group C,the admission to communication time,communication to signature time,transport time,door to balloon time were shortened(P<0.01),and no difference in PCI time,admission to communication time(P>0.05).Conclusions:Attributed the symptoms to angina pectoris can significantly shorten pre-hospital delay and balloon time.The implementation of clinical pathway can shorten door to balloon time.If the ratio of communication time in door to balloon time was long,it will affect door to balloon time.
Objective:To analyze the influence factors of symptom-to-balloon time during percutaneous coronary intervention(PCI) in myocardial infarction patients with ST-segment elevation.Methods:Data of 47 patients with ST-segment elevation myocardial infarction who received primary PCI during October 2012 to February 2014 were analyzed.All these patients were divided into group A(attributed the symptoms to angina pectoris) and group B(not attributed the symptoms to angina pectoris);group C(clinical pathway group) and D group(not clinical pathway group).The symptoms to visit time,whether to use the emergency service system,communication time,communication to signature time,clinic to balloon time,PCI operation time,transfer to catheter room time were compared between group A and B;the time for communication,communication to signature time,clinic to balloon time,PCI operation time,transfer to catheter room time were compared between group C and D.Results:Compared with group B,the symptoms to treatment time,door to balloon time in group A were shortened(P<0.01 and P<0.05),the proportion of admission through emergency service system were higher(P<0.01),no differences between the communication to signature time and PCI time(P>0.05).Compared with group D,in group C,the admission to communication time,communication to signature time,transport time,door to balloon time were shortened(P<0.01),and no difference in PCI time,admission to communication time(P>0.05).Conclusions:Attributed the symptoms to angina pectoris can significantly shorten pre-hospital delay and balloon time.The implementation of clinical pathway can shorten door to balloon time.If the ratio of communication time in door to balloon time was long,it will affect door to balloon time.
The application of color Doppler ultrasound in the diagnosis and treatment of brachial artery injury
2015, 40(3): 378-380.
doi: 10.13898/j.cnki.issn.1000-2200.2015.03.029
Abstract:
Objective:To explore the application effects of color Doppler ultrasound in the diagnosis and treatment of brachial artery injury.Methods:The color Doppler ultrasound imaging of brachial artery injury complicated with different degree blood supply obstacle of upper limb in 38 cases were observed,the treatment value of which was explored.Results:Twenty-one cases with brachial artery injury complicated with thrombosis were found using ultrasound,18 cases of which were determined by operation.Seventeen cases with possible brachial artery injury were found using ultrasound,15 cases of which were determined by operation.The thrombosis in brachial artery of patients decreased significantly 1 and 2 weeks after treatment.Conclusions:Color Doppler ultrasound is the most direct means in the diagnosis,treatment and prognosis of brachial artery injury,which is high accuracy.
Objective:To explore the application effects of color Doppler ultrasound in the diagnosis and treatment of brachial artery injury.Methods:The color Doppler ultrasound imaging of brachial artery injury complicated with different degree blood supply obstacle of upper limb in 38 cases were observed,the treatment value of which was explored.Results:Twenty-one cases with brachial artery injury complicated with thrombosis were found using ultrasound,18 cases of which were determined by operation.Seventeen cases with possible brachial artery injury were found using ultrasound,15 cases of which were determined by operation.The thrombosis in brachial artery of patients decreased significantly 1 and 2 weeks after treatment.Conclusions:Color Doppler ultrasound is the most direct means in the diagnosis,treatment and prognosis of brachial artery injury,which is high accuracy.
2015, 40(3): 380-382.
doi: 10.13898/j.cnki.issn.1000-2200.2015.03.030
Abstract:
Objective:To investigate the clinical value of multislice spiral CT unenhanced scan and imaging reconstruction in the diagnosis of ureterolithiasis.Methods:The data of 64 layers spiral CT scan in 75 patients with ureteral calculus were retrospectively analyzed,the multiplanar and curved planar of ureter were reconstructed at workstation.Results:Eighty-seven ureteral stones in 75 patients were found,which included 22 stones in ureteropelvic junction,35 stones in the middle ureter and 30 stones in the distal ureter.Fifty-two patients with soft-tissue rim sign and 3 patients with the bladder filling defect complicated with ureterovesical junction calculus were observed.Compared with the conventional image measurement,the reconstruction image counld measure the stone size,and the classification levels of 14 stones were enhanced.Conclusions:The multislice spiral CT unenhanced scan and reconstruction can obtain good imaging of ureter,which can correct the classification level of stone,and provide the accurate and effective information in clinic.
Objective:To investigate the clinical value of multislice spiral CT unenhanced scan and imaging reconstruction in the diagnosis of ureterolithiasis.Methods:The data of 64 layers spiral CT scan in 75 patients with ureteral calculus were retrospectively analyzed,the multiplanar and curved planar of ureter were reconstructed at workstation.Results:Eighty-seven ureteral stones in 75 patients were found,which included 22 stones in ureteropelvic junction,35 stones in the middle ureter and 30 stones in the distal ureter.Fifty-two patients with soft-tissue rim sign and 3 patients with the bladder filling defect complicated with ureterovesical junction calculus were observed.Compared with the conventional image measurement,the reconstruction image counld measure the stone size,and the classification levels of 14 stones were enhanced.Conclusions:The multislice spiral CT unenhanced scan and reconstruction can obtain good imaging of ureter,which can correct the classification level of stone,and provide the accurate and effective information in clinic.
2015, 40(3): 383-385.
doi: 10.13898/j.cnki.issn.1000-2200.2015.03.031
Abstract:
Objective:To investigate the application of quality control circle(QCC) in reducing the loss of inpatient pharmacy drugs and improving the service quality of inpaitient pharmacy.Methods:The QCC was implemented for reducing the loss of inpatient pharmacy drugs,and the effect of which was evaluated.Results:The loss of inpatient pharmacy drugs decreased significantly,which decreased to 39.4% after implementing QCC.The effect of QCC action was good.Conclusions:The QCC action can reduce the loss of inpatient pharmacy drugs,and promote the rational use of the limited medical resources.
Objective:To investigate the application of quality control circle(QCC) in reducing the loss of inpatient pharmacy drugs and improving the service quality of inpaitient pharmacy.Methods:The QCC was implemented for reducing the loss of inpatient pharmacy drugs,and the effect of which was evaluated.Results:The loss of inpatient pharmacy drugs decreased significantly,which decreased to 39.4% after implementing QCC.The effect of QCC action was good.Conclusions:The QCC action can reduce the loss of inpatient pharmacy drugs,and promote the rational use of the limited medical resources.
2015, 40(3): 386-387,392.
doi: 10.13898/j.cnki.issn.1000-2200.2015.03.032
Abstract:
Objective:To establish the method of the microbial limit inspection of guihongqufeng wine.Methods:The flocculent precipitation of preparation was removed by membrane-filter procedure.The microbial limit of sample was inspected by culture medium dilution and membrane-filter procedure.The methodology was validated by the results of 6 positive bacteria experimental group,microbial group and control group.Results:The recoverys of bacterial colony in Escherichia coli,Staphylococcus aureus,Bacillus subtilis,Candida albicans and Aspergillus niger were more than 70%.All positive bacteria could be detected by the control germ test.Conclusions:The membrane-filter procedure can count the bacterial colony,the test organisms can be checked out by the methods of liquid preparation and control germ test.
Objective:To establish the method of the microbial limit inspection of guihongqufeng wine.Methods:The flocculent precipitation of preparation was removed by membrane-filter procedure.The microbial limit of sample was inspected by culture medium dilution and membrane-filter procedure.The methodology was validated by the results of 6 positive bacteria experimental group,microbial group and control group.Results:The recoverys of bacterial colony in Escherichia coli,Staphylococcus aureus,Bacillus subtilis,Candida albicans and Aspergillus niger were more than 70%.All positive bacteria could be detected by the control germ test.Conclusions:The membrane-filter procedure can count the bacterial colony,the test organisms can be checked out by the methods of liquid preparation and control germ test.
2015, 40(3): 388-392.
doi: 10.13898/j.cnki.issn.1000-2200.2015.03.033
Abstract:
Objective:To investigate the mental health status of the new generation migrant workers in Anhui province,and analyze its influencing factors.Methods:Seven hundred and eighty-eight home-going new generation migrant workers were randomly surveyed using the SCL-90 during the Spring Festival in Anhui Province.Results:The detection rate of psychological problems was 39.8%(including 15.5% cases with more than moderate psychological problem) in new generation migrant workers in Anhui,their mental health levels were significantly lower than the average level of normal people(P<0.01).The differences of the mental health levels in different genders(major in the total points of SCL-90,hostility,depression,anxiety and terror),different marital status(major in the total points of SCL-90,anxiety,terror and psychoticism),different educational levels(major in the somatization,hostility and terror),different ages(major in the somatization,total points of SCL-90 and others) and different income levels(major in the interpersonal relationship and depression) were statistically significant(P<0.05 to P<0.01).Conclusions:The mental health problems in new generation migrant workers are worse,the influencing factors of which include gender,age,marital status,educational level and income level.
Objective:To investigate the mental health status of the new generation migrant workers in Anhui province,and analyze its influencing factors.Methods:Seven hundred and eighty-eight home-going new generation migrant workers were randomly surveyed using the SCL-90 during the Spring Festival in Anhui Province.Results:The detection rate of psychological problems was 39.8%(including 15.5% cases with more than moderate psychological problem) in new generation migrant workers in Anhui,their mental health levels were significantly lower than the average level of normal people(P<0.01).The differences of the mental health levels in different genders(major in the total points of SCL-90,hostility,depression,anxiety and terror),different marital status(major in the total points of SCL-90,anxiety,terror and psychoticism),different educational levels(major in the somatization,hostility and terror),different ages(major in the somatization,total points of SCL-90 and others) and different income levels(major in the interpersonal relationship and depression) were statistically significant(P<0.05 to P<0.01).Conclusions:The mental health problems in new generation migrant workers are worse,the influencing factors of which include gender,age,marital status,educational level and income level.
2015, 40(3): 395-398.
doi: 10.13898/j.cnki.issn.1000-2200.2015.03.035
Abstract:
Objective:To investigate the influence of evidence-based nursing on complications and prognosis for patients with myasthenia gravis crisis.Methods:The research method of evidence-based medicine was used to the patients with myasthenia gravis crisis.Forty-four cases in intervention group were treated with evidence-based care,and another 38 patients in control group were just given routine nursing care.The incidence of complications and indicators of health economics were evaluated between the two groups.Results:With Evidence-based nursing,the incidences of pulmonary infection and affective disorder were lower than those in control group(P<0.05 and P<0.01).In addition,the length of stay and the hospitalization expenses were decreased in the intervention group.Conclusions:Evidence-based nursing can lower incidence of complications and gain better prognosis after myasthenia gravis crisis,which suggested that evidence-based nursing should be practiced on an early stage.
Objective:To investigate the influence of evidence-based nursing on complications and prognosis for patients with myasthenia gravis crisis.Methods:The research method of evidence-based medicine was used to the patients with myasthenia gravis crisis.Forty-four cases in intervention group were treated with evidence-based care,and another 38 patients in control group were just given routine nursing care.The incidence of complications and indicators of health economics were evaluated between the two groups.Results:With Evidence-based nursing,the incidences of pulmonary infection and affective disorder were lower than those in control group(P<0.05 and P<0.01).In addition,the length of stay and the hospitalization expenses were decreased in the intervention group.Conclusions:Evidence-based nursing can lower incidence of complications and gain better prognosis after myasthenia gravis crisis,which suggested that evidence-based nursing should be practiced on an early stage.
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