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2016 Vol. 41, No. 10
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2016, 41(10): 1261-1264.
doi: 10.13898/j.cnki.issn.1000-2200.2016.10.001
Abstract:
Objective: To investigate the influence of the low temperture(-18℃ and -72℃) on the viability and infectivity of Trichinella spiralis muscle larvae.Methods: The viability of the Trichinella spiralis muscle larvae in mice skeletal muscle were observed after -18 and -72℃ of freezing.Fifty-five mice were infected with 300 muscle larvaes treated with low temperature(-18 and -72℃) by oral.The muscle larvae in mice was collected after 35 d of infection,the reproductive capacity index(RCI) of which was determined.Results: The death rate of the muscle larvae stored at the -18℃ for 0 h,6 h,12 h,24 h,36 h and 48 h were 0.00%,6.30%,18.23%,35.81%,74.60% and 100.00%.The death rate of the muscle larvae stored at the -72℃ for 0 min,15 min,45 min and 60 min were 0.00%,21.21%,57.11%,86.24% and 100.00%,respectively.The death rate of the muscle larva stored at -18℃ and -72℃ increased with the prolonging of the storing time(P<0.01).The RCI of the muscle larvae stored at -18℃ for 0 h,6 h,12 h,24 h and 36 h were(163.70±10.70),(126.38±6.90),(68.58±4.83),(12.58±1.77) and(5.77±0.77),respectively,and the difference of which was statistically significant(P<0.01).The RCI of the muscle larva stored at -72℃ for 0 min,15 min,30 min,45 min,were(163.70±10.70),(18.19±2.15),(8.83±1.39) and(3.10±0.26),respectively,and the difference of which was statistically significant(P<0.01).The RCI of the muscle larva stored at the -18℃ or -72℃ decreased with the prolonging of the storing time(P<0.01).Conclusions: Cryopreservation can lead to the decreasing of viability and infectivity of Trichinella spiralis muscle larvae in Henan.The muscle larvae stored at the 18℃ for 48h or -72℃ for 60 min can be completely inactivated.
Objective: To investigate the influence of the low temperture(-18℃ and -72℃) on the viability and infectivity of Trichinella spiralis muscle larvae.Methods: The viability of the Trichinella spiralis muscle larvae in mice skeletal muscle were observed after -18 and -72℃ of freezing.Fifty-five mice were infected with 300 muscle larvaes treated with low temperature(-18 and -72℃) by oral.The muscle larvae in mice was collected after 35 d of infection,the reproductive capacity index(RCI) of which was determined.Results: The death rate of the muscle larvae stored at the -18℃ for 0 h,6 h,12 h,24 h,36 h and 48 h were 0.00%,6.30%,18.23%,35.81%,74.60% and 100.00%.The death rate of the muscle larvae stored at the -72℃ for 0 min,15 min,45 min and 60 min were 0.00%,21.21%,57.11%,86.24% and 100.00%,respectively.The death rate of the muscle larva stored at -18℃ and -72℃ increased with the prolonging of the storing time(P<0.01).The RCI of the muscle larvae stored at -18℃ for 0 h,6 h,12 h,24 h and 36 h were(163.70±10.70),(126.38±6.90),(68.58±4.83),(12.58±1.77) and(5.77±0.77),respectively,and the difference of which was statistically significant(P<0.01).The RCI of the muscle larva stored at -72℃ for 0 min,15 min,30 min,45 min,were(163.70±10.70),(18.19±2.15),(8.83±1.39) and(3.10±0.26),respectively,and the difference of which was statistically significant(P<0.01).The RCI of the muscle larva stored at the -18℃ or -72℃ decreased with the prolonging of the storing time(P<0.01).Conclusions: Cryopreservation can lead to the decreasing of viability and infectivity of Trichinella spiralis muscle larvae in Henan.The muscle larvae stored at the 18℃ for 48h or -72℃ for 60 min can be completely inactivated.
2016, 41(10): 1265-1268.
doi: 10.13898/j.cnki.issn.1000-2200.2016.10.002
Abstract:
Objective: To explore the number change of myeloid-derived suppressor cells(MDSCs) in rat bone marrow at different time-points after different fluid resuscitation of hemorrhagic shock.Methods: The rat model of hemorrhagic shock was established through femoral artery bleeding method.In early stage of fluid resuscitation,the rats were recovered with lactated Ringer solution(lactated Ringer solution group),crystal glue(crystal glue group) and 7.5% hypertonic sodium chloride(hypertonic sodium chloride group),then the rats were recovered with autologous blood transfusion.The rats were sacrificed after 12 h,24 h and 48 h of successful resuscitation,and the sham operation rat was set as the control group.The number changes of MDSCs in rat bone marrow were detected using flow cytometry.Results: The MAP in lactate Ringer solution group was higher than that in crystal glue group(P<0.05).Compared with the sham group,the proportion of MDSCs in rat bone marrow in lactate Ringer solution group,crystal glue group and hypertonic sodium chloride group at each time point were significantly lower(P<0.01).The proportion of MDSCs in rat bone marrow in hypertonic sodium chloride group at each time point were significantly lower than that in lactate Ringer solution group and crystal glue group(P<0.01).The differences of the MDSCs between lactate Ringer solution group and crystal glue group at 12 h and 24 h were not statistical significance(P>0.05),and the MDSCs in crystal glue group at 24 h was lower than that in lactate Ringer solution group(P>0.05).Conclusions: After the early fluid resuscitation of hemorrhagic shock,the number of MDSCs in bone marrow of rat increase at first,then decrease with the extend of time,which explains that the fluid resuscitation can moderately inhibit the number of MDSCs.Compared with the Ringer lactate fluid and crystal glue liquid,the hypertonic saline solution can effectively inhibit the number of MDSCs after the hypertonic saline solution resuscitation of hemorrhagic shock,which has strong immunoregulatory effects on hemorrhagic shock.
Objective: To explore the number change of myeloid-derived suppressor cells(MDSCs) in rat bone marrow at different time-points after different fluid resuscitation of hemorrhagic shock.Methods: The rat model of hemorrhagic shock was established through femoral artery bleeding method.In early stage of fluid resuscitation,the rats were recovered with lactated Ringer solution(lactated Ringer solution group),crystal glue(crystal glue group) and 7.5% hypertonic sodium chloride(hypertonic sodium chloride group),then the rats were recovered with autologous blood transfusion.The rats were sacrificed after 12 h,24 h and 48 h of successful resuscitation,and the sham operation rat was set as the control group.The number changes of MDSCs in rat bone marrow were detected using flow cytometry.Results: The MAP in lactate Ringer solution group was higher than that in crystal glue group(P<0.05).Compared with the sham group,the proportion of MDSCs in rat bone marrow in lactate Ringer solution group,crystal glue group and hypertonic sodium chloride group at each time point were significantly lower(P<0.01).The proportion of MDSCs in rat bone marrow in hypertonic sodium chloride group at each time point were significantly lower than that in lactate Ringer solution group and crystal glue group(P<0.01).The differences of the MDSCs between lactate Ringer solution group and crystal glue group at 12 h and 24 h were not statistical significance(P>0.05),and the MDSCs in crystal glue group at 24 h was lower than that in lactate Ringer solution group(P>0.05).Conclusions: After the early fluid resuscitation of hemorrhagic shock,the number of MDSCs in bone marrow of rat increase at first,then decrease with the extend of time,which explains that the fluid resuscitation can moderately inhibit the number of MDSCs.Compared with the Ringer lactate fluid and crystal glue liquid,the hypertonic saline solution can effectively inhibit the number of MDSCs after the hypertonic saline solution resuscitation of hemorrhagic shock,which has strong immunoregulatory effects on hemorrhagic shock.
2016, 41(10): 1269-1272.
doi: 10.13898/j.cnki.issn.1000-2200.2016.10.003
Abstract:
Objective: To observe the reverse effects of curcumin on Taxol resistance to human ovarian cancer A2780/Taxol cells and analyze the mechanism of the reverse effect of curcumin.Methods: Ovarian cancer cell A2780/Taxol were cultured in vitro,the cells were divided into control group(group A) and experimental groups (different concentrations of curcumin),the cell growth inhibition rate combined with the same concentration of paclitaxel in the two groups were detected by by thiazotyl blue tetrazolium bromide(MTT).The protein expressions of P-glycoprotein(P-gp) and Protein Kinase C-α(PKC-α) in the two groups were detected by Westernblot method.Results: Compared with group A,the cell growth inhibition rates were higher in all experimental groups (P<0.05 to P<0.01).The results of Western blot were shown that the expressions of P-gp and PKC-α in experimental group were significantly lower than those in A group(P<0.01).Conclusions: Curcumin blocked the products of multi-drug resistant protein-1/P-gp and PKC-α in ovarian cancer cells,then increased the toxicity of paclitaxel on the cell and reduced the drug resistance.
Objective: To observe the reverse effects of curcumin on Taxol resistance to human ovarian cancer A2780/Taxol cells and analyze the mechanism of the reverse effect of curcumin.Methods: Ovarian cancer cell A2780/Taxol were cultured in vitro,the cells were divided into control group(group A) and experimental groups (different concentrations of curcumin),the cell growth inhibition rate combined with the same concentration of paclitaxel in the two groups were detected by by thiazotyl blue tetrazolium bromide(MTT).The protein expressions of P-glycoprotein(P-gp) and Protein Kinase C-α(PKC-α) in the two groups were detected by Westernblot method.Results: Compared with group A,the cell growth inhibition rates were higher in all experimental groups (P<0.05 to P<0.01).The results of Western blot were shown that the expressions of P-gp and PKC-α in experimental group were significantly lower than those in A group(P<0.01).Conclusions: Curcumin blocked the products of multi-drug resistant protein-1/P-gp and PKC-α in ovarian cancer cells,then increased the toxicity of paclitaxel on the cell and reduced the drug resistance.
2016, 41(10): 1272-1274.
doi: 10.13898/j.cnki.issn.1000-2200.2016.10.004
Abstract:
Objective: To analyze the correlation of the bone mineral density(BMD) changes of lumbar and femoral neck with age,gender,disease duration,hip lesion and acute phase reactant in patients with ankylosing spondylitis(AS).Methods: The BMD of lumbar(L2-L4) and femoral neck were detected using Dual-energy X-ray absorptiometry method,and T value was used as the diagnosis criteria of osteoporosis.Results: The BMD of lumbar and femoral neck in male AS patient was significantly lower than that in female AS patient(P<0.05).The difference of the BMD of femoral neck between the patients with AS complicated with and without hip lesion was not statistically significant(P>0.05).The T value of BMD of lumbar was negatively correlated with the age of patient(P<0.05),but the disease duration and acute phase reactant were not correlated with the BMD of AS patient(P>0.05).Conclusions: Compared with female AS patient,the osteopenia and osteoporosis in male AS patient are ease to happen,and the occurrence rate of osteoporosis of lumbar increases with the age of patient increasing.Disease duration,hip lesion and acute phase reactant have no significant influence on the BMD change in AS patient.
Objective: To analyze the correlation of the bone mineral density(BMD) changes of lumbar and femoral neck with age,gender,disease duration,hip lesion and acute phase reactant in patients with ankylosing spondylitis(AS).Methods: The BMD of lumbar(L2-L4) and femoral neck were detected using Dual-energy X-ray absorptiometry method,and T value was used as the diagnosis criteria of osteoporosis.Results: The BMD of lumbar and femoral neck in male AS patient was significantly lower than that in female AS patient(P<0.05).The difference of the BMD of femoral neck between the patients with AS complicated with and without hip lesion was not statistically significant(P>0.05).The T value of BMD of lumbar was negatively correlated with the age of patient(P<0.05),but the disease duration and acute phase reactant were not correlated with the BMD of AS patient(P>0.05).Conclusions: Compared with female AS patient,the osteopenia and osteoporosis in male AS patient are ease to happen,and the occurrence rate of osteoporosis of lumbar increases with the age of patient increasing.Disease duration,hip lesion and acute phase reactant have no significant influence on the BMD change in AS patient.
2016, 41(10): 1275-1277.
doi: 10.13898/j.cnki.issn.1000-2200.2016.10.005
Abstract:
Objective: To investigate the clinical value of the percutaneous catheter drainage(PCD) guided by ultrasound in severe acute pancreatitis(SAP) complicated with peripancreatic effusion.Methods: Seventy-three patients with SAP were randomly divided into the observation group(38 cases) and control group(35 cases).The control group and observation group were treated with conservative therapy and PCD guided by ultrasound ocmbined with conservative therapy,respectively.The recovery time of abdominal pain,abdominal distention,serum amylase and urine amylase,time of antibiotic use,hospital stay,cure rate,mortality and incidence rate of local complication,and leukocyte count,procalcitonin,serum calcium and pressure change of abdominal cavity in certain time between two groups were compared.Results: Compared with the control group,the recovery time of abdominal pain,abdominal distention,serum amylase and urine amylase,time of antibiotic use and hospital stay in observation group were significantly shorter(P<0.01),and the leukocyte count,procalcitonin,serum calcium and pressure change of abdominal cavity in certain time decreased in observation group(P<0.05 to P<0.01).The differences of the treatment effect and incidence rate of complication bettween two groups were not statistically significant(P>0.05).Conclusions: The treatment of the SAP complicated with peripancreatic effusion with PCD guided by ultrasound is good effect,low complication,safe and reliable,which has great application value in clinic.
Objective: To investigate the clinical value of the percutaneous catheter drainage(PCD) guided by ultrasound in severe acute pancreatitis(SAP) complicated with peripancreatic effusion.Methods: Seventy-three patients with SAP were randomly divided into the observation group(38 cases) and control group(35 cases).The control group and observation group were treated with conservative therapy and PCD guided by ultrasound ocmbined with conservative therapy,respectively.The recovery time of abdominal pain,abdominal distention,serum amylase and urine amylase,time of antibiotic use,hospital stay,cure rate,mortality and incidence rate of local complication,and leukocyte count,procalcitonin,serum calcium and pressure change of abdominal cavity in certain time between two groups were compared.Results: Compared with the control group,the recovery time of abdominal pain,abdominal distention,serum amylase and urine amylase,time of antibiotic use and hospital stay in observation group were significantly shorter(P<0.01),and the leukocyte count,procalcitonin,serum calcium and pressure change of abdominal cavity in certain time decreased in observation group(P<0.05 to P<0.01).The differences of the treatment effect and incidence rate of complication bettween two groups were not statistically significant(P>0.05).Conclusions: The treatment of the SAP complicated with peripancreatic effusion with PCD guided by ultrasound is good effect,low complication,safe and reliable,which has great application value in clinic.
2016, 41(10): 1278-1281.
doi: 10.13898/j.cnki.issn.1000-2200.2016.10.006
Abstract:
Objective: To analyze the pathogenic bacteria characteristics and its drug resistance in neonatal sepsis and ventilator associated pneumonia(VAP) in NICU,and provide the evidence in selecting antibiotics.Methods: The data of blood culture and drug susceptibility in 97 neonatal sepsis patients were retrospectively analyzed.Results: Ninety-seven pathogenic bacteria strains were detected in blood culture.In blood culture,the gram positive bacteria mostly included staphylococcus epidermidis,staphylococcus haemolyticusand staphylococcus hominis,which was highly resistant to penicillin,erythromycin and oxacillin,and individually resistant to linezolid and vancomycin.In blood culture,the gram-negative bacteria mostly included klebsiella pneumoniae and escherichia Coli,which was highly resistant to ampicillin,aztreonam,cefazolin,ceftriaxone and ceftazidime.Forty-two pathogenic bacteria strains were detected in sputum culture(including 1 case with bacterial complicated with fungal infection),In sputum culture,thirty-nine gram negative bacteria were detected,which mainly included acinetobacter bauman,serratia marcescens,stenotrophomonas maltophilia and klebsiella pneumonia,and was multi drug resistant bacteria.The fungi detected by sputum culture was candida albicans.Conclusions: Blood culture result shows that the staphylococcus is main infection in neonatal sepsis,the sputum culture result in ventilator associated pneumonia patient shows that the gram-negative bacilli is main infection.The antibiotics should be reasonably applied according to the test result,which can improve the efficacy and reduce the resistance of bacteria.
Objective: To analyze the pathogenic bacteria characteristics and its drug resistance in neonatal sepsis and ventilator associated pneumonia(VAP) in NICU,and provide the evidence in selecting antibiotics.Methods: The data of blood culture and drug susceptibility in 97 neonatal sepsis patients were retrospectively analyzed.Results: Ninety-seven pathogenic bacteria strains were detected in blood culture.In blood culture,the gram positive bacteria mostly included staphylococcus epidermidis,staphylococcus haemolyticusand staphylococcus hominis,which was highly resistant to penicillin,erythromycin and oxacillin,and individually resistant to linezolid and vancomycin.In blood culture,the gram-negative bacteria mostly included klebsiella pneumoniae and escherichia Coli,which was highly resistant to ampicillin,aztreonam,cefazolin,ceftriaxone and ceftazidime.Forty-two pathogenic bacteria strains were detected in sputum culture(including 1 case with bacterial complicated with fungal infection),In sputum culture,thirty-nine gram negative bacteria were detected,which mainly included acinetobacter bauman,serratia marcescens,stenotrophomonas maltophilia and klebsiella pneumonia,and was multi drug resistant bacteria.The fungi detected by sputum culture was candida albicans.Conclusions: Blood culture result shows that the staphylococcus is main infection in neonatal sepsis,the sputum culture result in ventilator associated pneumonia patient shows that the gram-negative bacilli is main infection.The antibiotics should be reasonably applied according to the test result,which can improve the efficacy and reduce the resistance of bacteria.
2016, 41(10): 1282-1284,1287.
doi: 10.13898/j.cnki.issn.1000-2200.2016.10.007
Abstract:
Objective: To investigate the value of the combined detection of peptidylarginine deaminase-4(PADI-4) and anti-cyclic citrullinated peptide(anti-CCP) antibody in the diagnosis of rheumatoid arthritis(RA).Methods: The levels of PADI-4,anti-CCP antibody,anti-MCV antibody,AFA antibody and anti-RA33 antibody in 58 patients with RA(RA group),40 patients with other rheumatoid disease(non-RA group) and 30 healthy people(control group) were detected by ELISA.The ROC curve,sensitivity,specificity,relevance and diagnostic effectiveness in all cases were analyzed.Results: The serum levels of PADI-4,anti-CCP antibody,anti-MCV antibody,AFA antibody and anti-RA33 antibody in RA patients were significantly higher than those in non-RA group and control group(P<0.01).The ROC curve showed that the best critical value of PADI-4 and anti-CCP antibody in the diagnosis of RA were 1.284 U/L and 26.365 RU/mL,the sensitivity and specificity of PADI-4 and anti-CCP antibody were 62.1% & 81.1% and 91.4% & 95.7%,respectively.PADI-4 was positive correlation with AFA antibody,anti-RA33 antibody and anti-MCV antibody(P<0.01),but the PADI-4 was not correlation with anti-CCP antibody(P>0.05).Among the combined detection of multiple antibodies,the specificity of the PADI-4 and anti-CCP antibody in the diagnosis of RA was 100.0%,and the positive detection of PADI-4 and anti-CCP antibody were 91.4% and 95.7%,respectively.Conclusions: The combined detection of PADI and anti-CCP antibody can improve the specificity and sensitivity of RA,which can help the diagnosis of RA.
Objective: To investigate the value of the combined detection of peptidylarginine deaminase-4(PADI-4) and anti-cyclic citrullinated peptide(anti-CCP) antibody in the diagnosis of rheumatoid arthritis(RA).Methods: The levels of PADI-4,anti-CCP antibody,anti-MCV antibody,AFA antibody and anti-RA33 antibody in 58 patients with RA(RA group),40 patients with other rheumatoid disease(non-RA group) and 30 healthy people(control group) were detected by ELISA.The ROC curve,sensitivity,specificity,relevance and diagnostic effectiveness in all cases were analyzed.Results: The serum levels of PADI-4,anti-CCP antibody,anti-MCV antibody,AFA antibody and anti-RA33 antibody in RA patients were significantly higher than those in non-RA group and control group(P<0.01).The ROC curve showed that the best critical value of PADI-4 and anti-CCP antibody in the diagnosis of RA were 1.284 U/L and 26.365 RU/mL,the sensitivity and specificity of PADI-4 and anti-CCP antibody were 62.1% & 81.1% and 91.4% & 95.7%,respectively.PADI-4 was positive correlation with AFA antibody,anti-RA33 antibody and anti-MCV antibody(P<0.01),but the PADI-4 was not correlation with anti-CCP antibody(P>0.05).Among the combined detection of multiple antibodies,the specificity of the PADI-4 and anti-CCP antibody in the diagnosis of RA was 100.0%,and the positive detection of PADI-4 and anti-CCP antibody were 91.4% and 95.7%,respectively.Conclusions: The combined detection of PADI and anti-CCP antibody can improve the specificity and sensitivity of RA,which can help the diagnosis of RA.
2016, 41(10): 1285-1287.
doi: 10.13898/j.cnki.issn.1000-2200.2016.10.008
Abstract:
Objective: To study of the clinical value of dynamic electrocardiogram(DCG) in the diagnosis of acute coronary syndrome(ACS).Methods: Eighty-six patients diagnosed by ACS were detected using DCG and coronary angiography(CAG).The DCG diagnosis index for ACS was calculated using CAG examination as the gold standard.The correlation of the number of coronary artery lesion number and degree of stenosis of ACS diagnosed by DCG were analyzed.Results: Seventy-two ACS patients were diagnosed by CAG.The sensitivity,specificity,misdiagnosis rate,missed diagnosis rate,positive predictive value and negative predictive value of DCG in the diagnosis of ACS were 87.50%,85.71%,14.29%,12.50%,96.92% and 57.14%,respectively.The results of two kinds of methods examination were highly consistent(Kappa=0.609,P<0.01).The disease positive rates of the single-vessel coronary artery,double vessel coronary artery and three or left main vessel coronary artery of DCG diagnosis were 68.75%,92.59% and 93.10%,respectively,and the differences of whose were statistically significant(P<0.05).The positive rates of mild stenosis,moderate stenosis and severe stenosis of the DCG diagnosis were 66.67%,93.75 and 95.45%,respectively,and the differences of whose were statistically significant(P<0.01). Conclusions: The ACS diagnosed with DCG and CAG is high consistency,the positive rates of DCG in diagnosing the double vessel disease,three or left main vessel disease,and moderate and severe stenosis are high.
Objective: To study of the clinical value of dynamic electrocardiogram(DCG) in the diagnosis of acute coronary syndrome(ACS).Methods: Eighty-six patients diagnosed by ACS were detected using DCG and coronary angiography(CAG).The DCG diagnosis index for ACS was calculated using CAG examination as the gold standard.The correlation of the number of coronary artery lesion number and degree of stenosis of ACS diagnosed by DCG were analyzed.Results: Seventy-two ACS patients were diagnosed by CAG.The sensitivity,specificity,misdiagnosis rate,missed diagnosis rate,positive predictive value and negative predictive value of DCG in the diagnosis of ACS were 87.50%,85.71%,14.29%,12.50%,96.92% and 57.14%,respectively.The results of two kinds of methods examination were highly consistent(Kappa=0.609,P<0.01).The disease positive rates of the single-vessel coronary artery,double vessel coronary artery and three or left main vessel coronary artery of DCG diagnosis were 68.75%,92.59% and 93.10%,respectively,and the differences of whose were statistically significant(P<0.05).The positive rates of mild stenosis,moderate stenosis and severe stenosis of the DCG diagnosis were 66.67%,93.75 and 95.45%,respectively,and the differences of whose were statistically significant(P<0.01). Conclusions: The ACS diagnosed with DCG and CAG is high consistency,the positive rates of DCG in diagnosing the double vessel disease,three or left main vessel disease,and moderate and severe stenosis are high.
2016, 41(10): 1288-1289,1292.
doi: 10.13898/j.cnki.issn.1000-2200.2016.10.009
Abstract:
Objective: To further improve the clinical effects of patients with breast cancer,and compare and analyze the value and side reaction of Kang'ai injection based on conventional chemotherapy.Methods: One hundred and six patients with breast cancer were randomly divided into the observation group and control group according to the randomized double-blind controlled principle(53 cases each group).All patients were treated with the routine CTF scheme(cyclophosphamide,pirarubicin and fluorouracil)chemotherapy,the observation group were additionally treated with Kang'ai injection.The total effective rate and incidence rate of adverse reaction between two groups were compared.Results: The difference of the total effective rate of treatment between two groups was not statistically significant(P>0.05).Compared with the control group,the incidence of adverse reactiyon in observation group significantly decreased,the difference of which was statistically significant(P<0.05-P<0.01).Conclusions: The treatment of the postoperative patients with breast cancer with Kang'ai injection based on the CTF chemotherapy can significantly reduce the adverse reaction and pain,which is worth of recommendation.
Objective: To further improve the clinical effects of patients with breast cancer,and compare and analyze the value and side reaction of Kang'ai injection based on conventional chemotherapy.Methods: One hundred and six patients with breast cancer were randomly divided into the observation group and control group according to the randomized double-blind controlled principle(53 cases each group).All patients were treated with the routine CTF scheme(cyclophosphamide,pirarubicin and fluorouracil)chemotherapy,the observation group were additionally treated with Kang'ai injection.The total effective rate and incidence rate of adverse reaction between two groups were compared.Results: The difference of the total effective rate of treatment between two groups was not statistically significant(P>0.05).Compared with the control group,the incidence of adverse reactiyon in observation group significantly decreased,the difference of which was statistically significant(P<0.05-P<0.01).Conclusions: The treatment of the postoperative patients with breast cancer with Kang'ai injection based on the CTF chemotherapy can significantly reduce the adverse reaction and pain,which is worth of recommendation.
2016, 41(10): 1290-1292.
doi: 10.13898/j.cnki.issn.1000-2200.2016.10.010
Abstract:
Objective: To explore the clinical application value of the respirator parameters regulated by the difference of pulmonary alveoli-artery oxygen pressure in children with severe pneumonia.Methods: One hundred and eight children with severe pneumonia were randomly divided into the observation group and control group(54 cases each group),the patients were diagnosed and treated supportively.The control group and observation group were treated with common respirator and respirator with the parameter regulated by the difference of pulmonary alveoli-artery oxygen pressure,respectively.The treatment efficacy and clinical manifestation between two groups were compared.Results: During the 1 to 24 h of mechanical ventilation,the PaO2 levels in observation group was significantly higher than that in control group(P<0.01),and the difference of the PaCO2 level between two groups was not statistically significant(P>0.05).The ventilation time,pH and oxygenation index in observation group were significantly higher than those in control group(P<0.01).The total effective rates in observation group and control group were 92.59% and 70.37%,respectively,the difference of which was statistically significant(P<0.01).Conclusions: The respirator parameter regulated by the difference of pulmonary alveoli-artery oxygen pressure can improve the treatment efficacy,and reduce the complication and mortality of patients.
Objective: To explore the clinical application value of the respirator parameters regulated by the difference of pulmonary alveoli-artery oxygen pressure in children with severe pneumonia.Methods: One hundred and eight children with severe pneumonia were randomly divided into the observation group and control group(54 cases each group),the patients were diagnosed and treated supportively.The control group and observation group were treated with common respirator and respirator with the parameter regulated by the difference of pulmonary alveoli-artery oxygen pressure,respectively.The treatment efficacy and clinical manifestation between two groups were compared.Results: During the 1 to 24 h of mechanical ventilation,the PaO2 levels in observation group was significantly higher than that in control group(P<0.01),and the difference of the PaCO2 level between two groups was not statistically significant(P>0.05).The ventilation time,pH and oxygenation index in observation group were significantly higher than those in control group(P<0.01).The total effective rates in observation group and control group were 92.59% and 70.37%,respectively,the difference of which was statistically significant(P<0.01).Conclusions: The respirator parameter regulated by the difference of pulmonary alveoli-artery oxygen pressure can improve the treatment efficacy,and reduce the complication and mortality of patients.
2016, 41(10): 1293-1296.
doi: 10.13898/j.cnki.issn.1000-2200.2016.10.011
Abstract:
Objective: To investigate the pregnancy and its influencing factors in no contraception patients after myomectomy.Methods: One hundred and twelve patients after myomectomy were investigated using consulting medical record and telephone consultation.The demographics,operation situation,hysteromyoma type and pregnant outcome in no contraception patients were recorded.Results: The pregnancy rate in patients with age ≥35(56.1%) was lower than that in patients with age<35(87.3%)(P<0.01).The pregnancy rate in patients treated with assisting reproductive technology(50.0%) was lower than that in patients treated without assisting reproductive technology(79.0%)(P<0.05).The pregnancy rate in patients with higher education(88.6%) was higher than that in patients without higher education(67.6%)(P<0.01).The more the pregnancy number was,the less the postoperative pregnancy rate was(P<0.01).The differences of the postoperative pregnancy rate in different operation method,preoperative symptom,and number and size of hysteromyoma were not statistically significant(P>0.05).Conclusions: Age,pregnancy history and infertility factor are the influencing factors of pregnancy in patient after myomectomy,the operation method and hysteromyoma type have not effect on the postoperative pregnancy.
Objective: To investigate the pregnancy and its influencing factors in no contraception patients after myomectomy.Methods: One hundred and twelve patients after myomectomy were investigated using consulting medical record and telephone consultation.The demographics,operation situation,hysteromyoma type and pregnant outcome in no contraception patients were recorded.Results: The pregnancy rate in patients with age ≥35(56.1%) was lower than that in patients with age<35(87.3%)(P<0.01).The pregnancy rate in patients treated with assisting reproductive technology(50.0%) was lower than that in patients treated without assisting reproductive technology(79.0%)(P<0.05).The pregnancy rate in patients with higher education(88.6%) was higher than that in patients without higher education(67.6%)(P<0.01).The more the pregnancy number was,the less the postoperative pregnancy rate was(P<0.01).The differences of the postoperative pregnancy rate in different operation method,preoperative symptom,and number and size of hysteromyoma were not statistically significant(P>0.05).Conclusions: Age,pregnancy history and infertility factor are the influencing factors of pregnancy in patient after myomectomy,the operation method and hysteromyoma type have not effect on the postoperative pregnancy.
2016, 41(10): 1296-1298.
doi: 10.13898/j.cnki.issn.1000-2200.2016.10.012
Abstract:
Objective: To investigate the value of β2-microglobuin(β2-MG) in the evaluation of tubulointerstitial injury in IgA nephropathy(IgAN).Methods: The levels of β2-MG in blood and urine and scores of tubulointerstitial injury in 201 IgAN patients were investigated using the immunoturbidimetric method and Katafuchi semi-quantitative standard,respectively.Results: With the aggravation of tubulointerstitial injury,the levels of β2-MG in blood and urine increased significantly.The levels of β2-MG in blood and urine were positive correlation with the tubulointerstitial injury(P<0.01).When the level of serum β2-MG was normal(<2.2 mg/L),the tubulointerstitial lesion was found in 95.6% of patients,which included the moderate tubulointerstitial lesion in 13.2% of patients,and the level of β2-MG in urine was not correlation with the tubulointertitial lesion(P>0.05).Conclusions: The abnormal increasing of the serum level of β2-MG has great value in evaluating the tubulointerstitial injury of IgA nephropathy.
Objective: To investigate the value of β2-microglobuin(β2-MG) in the evaluation of tubulointerstitial injury in IgA nephropathy(IgAN).Methods: The levels of β2-MG in blood and urine and scores of tubulointerstitial injury in 201 IgAN patients were investigated using the immunoturbidimetric method and Katafuchi semi-quantitative standard,respectively.Results: With the aggravation of tubulointerstitial injury,the levels of β2-MG in blood and urine increased significantly.The levels of β2-MG in blood and urine were positive correlation with the tubulointerstitial injury(P<0.01).When the level of serum β2-MG was normal(<2.2 mg/L),the tubulointerstitial lesion was found in 95.6% of patients,which included the moderate tubulointerstitial lesion in 13.2% of patients,and the level of β2-MG in urine was not correlation with the tubulointertitial lesion(P>0.05).Conclusions: The abnormal increasing of the serum level of β2-MG has great value in evaluating the tubulointerstitial injury of IgA nephropathy.
2016, 41(10): 1299-1301,1305.
doi: 10.13898/j.cnki.issn.1000-2200.2016.10.013
Abstract:
Objective: To explore the effects of the laryngeal mask insertion during the induction of general anesthesia with remifentanil or different doses of dezocine on the half-effective target plasma concentration(Cp50) of propofol.Methods: One hundred and sixty patients scheduled by operation with general anesthesia were randomly divided into the group A,B,C and D(40 cases each group).The group B,C and D were treated with initial target controlled infusion of 3 μg/mL propofol,and group A were treated with initial target controlled infusion of 5 μg/mL propofol.The group B,C and D were treated with target controlled infusion of 2 ng/ml remifentanil,0.1 mg/kg dezocine and 0.15 mg/kg dezocine,respectively,and the group A were the same volume 0.9% sodium chloride injection.Laryngeal mask were placed after 20 minutes.The heart rate(HR),mean arterial pressure(MAP) and bispectral index(BIS) in all patients before induction of anesthesia,before laryngeal mask placing and at the time of laryngeal mask placement were recorded,and the propofol Cp50 were measured using the upper and lower cross method.Results: Before laryngeal mask,the HR in group A,C and D were significantly higher than that in group B(P<0.01),the HR in group C was significantly higher than that in group A and D(P<0.01),and the MAP in group B,C and D were significantly higher than that in group A(P<0.01).At the time of laryngeal mask placement,the HR in group B and D were significantly lower than that in group A and C(P<0.01).Compared with that of before induction of anesthesia,the HR in group B,C and D decreased significantly(P<0.01),and the MAP and BIS in all groups decreased significantly before laryngeal mask placing(P<0.01).Compared with that of before laryngeal mask placing,the HR,MAP and BIS in group A and B increased(P<0.05 to P<0.01),the MAP and BIS in group C increased(P<0.05),propofol Cp50 in groups B,C and D were significantly lower than that in group A(P<0.05),and propofol Cp50 in groups B and D were significantly lower than that in group C at the time of laryngeal mask placing(P<0.01).Conclusions: Remifentanil or 0.15 mg/kg dezocine can effective reduce the effective dose of propofol Cp50,but the dezocine in hemodynamics is more stable than that of remifentanil during the induction of general anesthesia and laryngeal mask.
Objective: To explore the effects of the laryngeal mask insertion during the induction of general anesthesia with remifentanil or different doses of dezocine on the half-effective target plasma concentration(Cp50) of propofol.Methods: One hundred and sixty patients scheduled by operation with general anesthesia were randomly divided into the group A,B,C and D(40 cases each group).The group B,C and D were treated with initial target controlled infusion of 3 μg/mL propofol,and group A were treated with initial target controlled infusion of 5 μg/mL propofol.The group B,C and D were treated with target controlled infusion of 2 ng/ml remifentanil,0.1 mg/kg dezocine and 0.15 mg/kg dezocine,respectively,and the group A were the same volume 0.9% sodium chloride injection.Laryngeal mask were placed after 20 minutes.The heart rate(HR),mean arterial pressure(MAP) and bispectral index(BIS) in all patients before induction of anesthesia,before laryngeal mask placing and at the time of laryngeal mask placement were recorded,and the propofol Cp50 were measured using the upper and lower cross method.Results: Before laryngeal mask,the HR in group A,C and D were significantly higher than that in group B(P<0.01),the HR in group C was significantly higher than that in group A and D(P<0.01),and the MAP in group B,C and D were significantly higher than that in group A(P<0.01).At the time of laryngeal mask placement,the HR in group B and D were significantly lower than that in group A and C(P<0.01).Compared with that of before induction of anesthesia,the HR in group B,C and D decreased significantly(P<0.01),and the MAP and BIS in all groups decreased significantly before laryngeal mask placing(P<0.01).Compared with that of before laryngeal mask placing,the HR,MAP and BIS in group A and B increased(P<0.05 to P<0.01),the MAP and BIS in group C increased(P<0.05),propofol Cp50 in groups B,C and D were significantly lower than that in group A(P<0.05),and propofol Cp50 in groups B and D were significantly lower than that in group C at the time of laryngeal mask placing(P<0.01).Conclusions: Remifentanil or 0.15 mg/kg dezocine can effective reduce the effective dose of propofol Cp50,but the dezocine in hemodynamics is more stable than that of remifentanil during the induction of general anesthesia and laryngeal mask.
2016, 41(10): 1302-1305.
doi: 10.13898/j.cnki.issn.1000-2200.2016.10.014
Abstract:
Objective: To explore the safety and effectiveness of transuretheral plasmakinetic resection of prostate(PKRP) in the treatment of benign prostatic hyperplasia(BPH) with the prostate volume more than 80 mL.Methods: Forty-five BPH cases with the prostate volume more than 80 mL and functional capacity more than 4 METs were treated with PKRP.The central venous pressure(CVP) was monitored during the operation,the 20 to 40 mg of furosemide was intravenously administrated in the patients with CVP more than 3 cm H2O or normal value.The operation time,the levels of pre- and post-operation hemoglobin,hematocrit and serum sodium,and the maximum flow rate(Qmax),international prostate symptom score(IPSS),quality of life(QOL) and complication after 3,6 and 12 months of operation were analyzed.Results: The operations in 45 cases with the prostate volume more than 80 mL were successful,no case was transferred to open surgery and transfused.The operation time of patients was(92.56±29.69)min.The differences of the levels of sodium,hemoglobin and hematocrit between before and after operation were statistically significant(P>0.05).Compared with theses before operation,the Qmax,IPSS and QOL after 3,6 and 12 months of operation were significantly improved(P<0.01).Conclusions: In the case of functional capacity more than 4 METs,getting perioperative ready and monitoring intraoperative central venous pressure,the PKRP in the treatment of BPH with the prostate volume more than 80 mL is safe and effective.
Objective: To explore the safety and effectiveness of transuretheral plasmakinetic resection of prostate(PKRP) in the treatment of benign prostatic hyperplasia(BPH) with the prostate volume more than 80 mL.Methods: Forty-five BPH cases with the prostate volume more than 80 mL and functional capacity more than 4 METs were treated with PKRP.The central venous pressure(CVP) was monitored during the operation,the 20 to 40 mg of furosemide was intravenously administrated in the patients with CVP more than 3 cm H2O or normal value.The operation time,the levels of pre- and post-operation hemoglobin,hematocrit and serum sodium,and the maximum flow rate(Qmax),international prostate symptom score(IPSS),quality of life(QOL) and complication after 3,6 and 12 months of operation were analyzed.Results: The operations in 45 cases with the prostate volume more than 80 mL were successful,no case was transferred to open surgery and transfused.The operation time of patients was(92.56±29.69)min.The differences of the levels of sodium,hemoglobin and hematocrit between before and after operation were statistically significant(P>0.05).Compared with theses before operation,the Qmax,IPSS and QOL after 3,6 and 12 months of operation were significantly improved(P<0.01).Conclusions: In the case of functional capacity more than 4 METs,getting perioperative ready and monitoring intraoperative central venous pressure,the PKRP in the treatment of BPH with the prostate volume more than 80 mL is safe and effective.
2016, 41(10): 1306-1308.
doi: 10.13898/j.cnki.issn.1000-2200.2016.10.015
Abstract:
Objective: To study the correlation between ischemic cerebrovascular disease(ICVD) and ankle brachial index(ABI).Methods: The ABI measurement and routine biochemical tests were implemented in 120 ICVD patients diagnosed by arotid artery ultrasonography and transcranial color doppler(TCD) ultrasound.The patients were divided into the different groups according to the vascular stenosis degree,blood vessel number of lesions,and different Chinese ischemic stroke subtypes(CISS).The relationship between the intracranial arterial stenosis,number and location of lesions and different types of stroke,and ABI were compared.The cardiovascular events were observed during the period of 1-year following-up,and the correlation between cardiovascular events and ABI were analyzed.Results: With the number and extent of stenosis increasing,the abnormal rate of ABI increased,and the average value of ABI decreased(P<0.05 to P<0.01).The ABI value in single artery lesion group was significantly higher than that in large artery atherosclerosis group(P<0.01).The total incidence of cardiovascular event in normal ABI group(12.5%) was significantly lower than that in abnormal ABI group(48.8%)(P<0.01).Conclusions: The intracranial arterial ischemic degree,number and location of lesion and prognosis are related to the ABI.The ABI has high predictive value in severe intracranial artery stenosis,more than 3 branches lesions,large artery atheroscleosis disease classification and cardiovascular event.
Objective: To study the correlation between ischemic cerebrovascular disease(ICVD) and ankle brachial index(ABI).Methods: The ABI measurement and routine biochemical tests were implemented in 120 ICVD patients diagnosed by arotid artery ultrasonography and transcranial color doppler(TCD) ultrasound.The patients were divided into the different groups according to the vascular stenosis degree,blood vessel number of lesions,and different Chinese ischemic stroke subtypes(CISS).The relationship between the intracranial arterial stenosis,number and location of lesions and different types of stroke,and ABI were compared.The cardiovascular events were observed during the period of 1-year following-up,and the correlation between cardiovascular events and ABI were analyzed.Results: With the number and extent of stenosis increasing,the abnormal rate of ABI increased,and the average value of ABI decreased(P<0.05 to P<0.01).The ABI value in single artery lesion group was significantly higher than that in large artery atherosclerosis group(P<0.01).The total incidence of cardiovascular event in normal ABI group(12.5%) was significantly lower than that in abnormal ABI group(48.8%)(P<0.01).Conclusions: The intracranial arterial ischemic degree,number and location of lesion and prognosis are related to the ABI.The ABI has high predictive value in severe intracranial artery stenosis,more than 3 branches lesions,large artery atheroscleosis disease classification and cardiovascular event.
2016, 41(10): 1309-1311,1315.
doi: 10.13898/j.cnki.issn.1000-2200.2016.10.016
Abstract:
Objective: To explore the surgical technique and advantage of the modified laparoscopic myomectomy.Methods: One hundred patients with fibroid,who wanted to retain uterine,were randomly divided into the observation group(group A) and control group(group B)(60 cases each group).The observation group and control group were treated with the modified laparoscopic myomectomy and conventional laparoscopic myomectomy,respectively.According to the diameter of fibroid,the observation group and control group were subdivided into group A1(<6cm) & group A2(≥ 6cm),and group B1(<6cm) & group B2(≥6cm),respectively.The operative time,blood loss and postoperative fever between group A1 and B1,and between group A2 and B2 were compared.Results: All operations in all patients were completed under laparoscope,no case was treated with laparotomy,no serious complication was found during the operation and after operation.The operation time in group A1 was shorter than that in group B1(P<0.05),the difference of the intraoperative blood loss between group A1 and group B1 was not statistically significant(P>0.05).The operation time and intraoperative blood loss in group A2 less than those in group B2(P>0.05),the postoperative fever between group A2 and group B2 was not statistically significant(P>0.05).Conclusions: Compared with the traditional surgery,the modified laparoscopic myomectomy in treating fibroid is feasible,safe,less trauma,short operation time and less bleeding,especially for large uterine fibroid.
Objective: To explore the surgical technique and advantage of the modified laparoscopic myomectomy.Methods: One hundred patients with fibroid,who wanted to retain uterine,were randomly divided into the observation group(group A) and control group(group B)(60 cases each group).The observation group and control group were treated with the modified laparoscopic myomectomy and conventional laparoscopic myomectomy,respectively.According to the diameter of fibroid,the observation group and control group were subdivided into group A1(<6cm) & group A2(≥ 6cm),and group B1(<6cm) & group B2(≥6cm),respectively.The operative time,blood loss and postoperative fever between group A1 and B1,and between group A2 and B2 were compared.Results: All operations in all patients were completed under laparoscope,no case was treated with laparotomy,no serious complication was found during the operation and after operation.The operation time in group A1 was shorter than that in group B1(P<0.05),the difference of the intraoperative blood loss between group A1 and group B1 was not statistically significant(P>0.05).The operation time and intraoperative blood loss in group A2 less than those in group B2(P>0.05),the postoperative fever between group A2 and group B2 was not statistically significant(P>0.05).Conclusions: Compared with the traditional surgery,the modified laparoscopic myomectomy in treating fibroid is feasible,safe,less trauma,short operation time and less bleeding,especially for large uterine fibroid.
2016, 41(10): 1312-1315.
doi: 10.13898/j.cnki.issn.1000-2200.2016.10.017
Abstract:
Objective: To compare the clinical effects between endoscopic sinus surgery,nasal incision and endoscopic Caldwell-Luc surgery in the treatment of nasal inverted papilloma(NIP),and explore the application of three kinds of operations.Methods: One hundred and forty-one NIP patients were randomly divided into the endoscopic sinus surgery group,nasal incision group and endoscopic Caldwell-Luc surgery group using randomized parallel controlled study way.The clinical effects,complications and recurrence rate between the three kinds of operations were analyzed.Results: The differences of the operation time,blood loss and postoperative hospitalization time between three groups were statistically significant(P>0.01).During the following up period,5 cases in endoscopic sinus surgery group,7 cases in nasal incision group and 3 cases in endoscopic Caldwell-Luc surgery group lost to follow.The differences of the total recurrence rate,incidence of complication and total complications in type Ⅰ,Ⅱ and Ⅳ Krouse between three groups were not statistically significant(P>0.05).The differences of the recurrence rates in patients with type Ⅳ Krouse between three groups were statistically significant(P<0.05).The incidences of complication in patients with type Ⅳ Krouse in endoscopic sinus surgery group and nasal incision group were higher than that in endoscopic Caldwell-Luc surgery group(P<0.05).Conclusions: The endoscopic sinus surgery in the treatment of nasal inverted papilloma is short operation time,little bleeding and short hospital stay,which is more suitable for the patients with type Ⅰ to Ⅱ Krouse.The treatment of type Ⅲ Krouse with endoscopic Caldwell-Luc surgery can significantly reduce complications and recurrence rate,the effects of type Ⅳ Krouse patients treated with three kinds operation are not ideal.
Objective: To compare the clinical effects between endoscopic sinus surgery,nasal incision and endoscopic Caldwell-Luc surgery in the treatment of nasal inverted papilloma(NIP),and explore the application of three kinds of operations.Methods: One hundred and forty-one NIP patients were randomly divided into the endoscopic sinus surgery group,nasal incision group and endoscopic Caldwell-Luc surgery group using randomized parallel controlled study way.The clinical effects,complications and recurrence rate between the three kinds of operations were analyzed.Results: The differences of the operation time,blood loss and postoperative hospitalization time between three groups were statistically significant(P>0.01).During the following up period,5 cases in endoscopic sinus surgery group,7 cases in nasal incision group and 3 cases in endoscopic Caldwell-Luc surgery group lost to follow.The differences of the total recurrence rate,incidence of complication and total complications in type Ⅰ,Ⅱ and Ⅳ Krouse between three groups were not statistically significant(P>0.05).The differences of the recurrence rates in patients with type Ⅳ Krouse between three groups were statistically significant(P<0.05).The incidences of complication in patients with type Ⅳ Krouse in endoscopic sinus surgery group and nasal incision group were higher than that in endoscopic Caldwell-Luc surgery group(P<0.05).Conclusions: The endoscopic sinus surgery in the treatment of nasal inverted papilloma is short operation time,little bleeding and short hospital stay,which is more suitable for the patients with type Ⅰ to Ⅱ Krouse.The treatment of type Ⅲ Krouse with endoscopic Caldwell-Luc surgery can significantly reduce complications and recurrence rate,the effects of type Ⅳ Krouse patients treated with three kinds operation are not ideal.
2016, 41(10): 1316-1318.
doi: 10.13898/j.cnki.issn.1000-2200.2016.10.018
Abstract:
Objective: To investigate the correlation of the serum uric acid level with hypertension among health examinees in a tertiary hospital of Hefei.Methods: The data of general information,physical examination and blood biochemical examination in 9 421 health examinees from a tertiary hospital of Hefei were investigated in 2011,which was statistically analyzed using the SPSS software(version 18.0).Results: The average level of serum uric acid in all subjects was (334.1±82.29)μmol/L,and the incidence rate of hyperuricemia was 15.6%.With the increasing of the serum uric acid level,the average level of systolic and diastolic blood pressure increased(P<0.01).The incidence rate in the cases(the serum uric acid level ≥388 μmol/L) was the highest,and the incidence rate of hypertension increased with the increasing of the serum uric acid level(P<0.01).By adjusting the gender,age,body mass index,blood sugar,HDL,LDL,TC,TG,BUN and Cre facors,the serum uric acid level was the independent influencing factor of hypertension.Compared with the patients(the serum uric acid level <276 μmol/L),the multiples of hypertension onset in 276~μmol/L,330~μmol/L and ≥388 μmol/L cases were 1.230,1.456 and 1.732,respectively.Conclusions: The serum uric acid level is closely related to the blood pressure level and hypertension prevalence.The serum uric acid level has important clinical significance in the prevention of hypertension.
Objective: To investigate the correlation of the serum uric acid level with hypertension among health examinees in a tertiary hospital of Hefei.Methods: The data of general information,physical examination and blood biochemical examination in 9 421 health examinees from a tertiary hospital of Hefei were investigated in 2011,which was statistically analyzed using the SPSS software(version 18.0).Results: The average level of serum uric acid in all subjects was (334.1±82.29)μmol/L,and the incidence rate of hyperuricemia was 15.6%.With the increasing of the serum uric acid level,the average level of systolic and diastolic blood pressure increased(P<0.01).The incidence rate in the cases(the serum uric acid level ≥388 μmol/L) was the highest,and the incidence rate of hypertension increased with the increasing of the serum uric acid level(P<0.01).By adjusting the gender,age,body mass index,blood sugar,HDL,LDL,TC,TG,BUN and Cre facors,the serum uric acid level was the independent influencing factor of hypertension.Compared with the patients(the serum uric acid level <276 μmol/L),the multiples of hypertension onset in 276~μmol/L,330~μmol/L and ≥388 μmol/L cases were 1.230,1.456 and 1.732,respectively.Conclusions: The serum uric acid level is closely related to the blood pressure level and hypertension prevalence.The serum uric acid level has important clinical significance in the prevention of hypertension.
2016, 41(10): 1319-1322.
doi: 10.13898/j.cnki.issn.1000-2200.2016.10.019
Abstract:
Objective: To compare the preventive effects between dexmedetomidine and dezocine on shivering after spinal canal anesthesia.Methods: Ninety patients scheduled by unilateral knee replacement surgery under spinal canal anesthesia were randomly divided into the group D(using 0.5 μg/kg of dexmedetomidine),group Z(using 0.1 mg/kg of dezocine) and group C(using 0.9% of sodium chloride injection) (30 cases each group).All patients were anesthetized at L2-L3 using combined spinal and epidural anesthesia(CSEA).The drugs were pumped into after fixing anesthesia plane.The reaction and grading of shivering,oxygen saturation,nausea and vomiting were observed after the CSEA.The HR,MAP and Ramsay scores were recorded at the time of fixing anesthesia plane(T0),end of drug injection(T1),after 30 and 60 min of operation(T2 and T3) and end of operatiom(T4).Results: The differences of the shivering classification,and incidence of nausea and vomiting among group D,Z and C were statistically significant(P<0.05).The HR in group D and Z at T3 and T4 were less than those in group C(P<0.01).The differences of the MAP at T0 to T4 among the 3 groups were not statistically significant(P>0.05).The sedative effects in group D at T1 to T4 were better than that in group Z and C(P<0.01),and no excessive sedation was identified.Conclusions: The dexmedetomidine can effectively decrease the incidence of shivering after CSEA,has good sedative effect,and does not increase the incidence of postoperative adverse reaction,which is suitable for clinical application.
Objective: To compare the preventive effects between dexmedetomidine and dezocine on shivering after spinal canal anesthesia.Methods: Ninety patients scheduled by unilateral knee replacement surgery under spinal canal anesthesia were randomly divided into the group D(using 0.5 μg/kg of dexmedetomidine),group Z(using 0.1 mg/kg of dezocine) and group C(using 0.9% of sodium chloride injection) (30 cases each group).All patients were anesthetized at L2-L3 using combined spinal and epidural anesthesia(CSEA).The drugs were pumped into after fixing anesthesia plane.The reaction and grading of shivering,oxygen saturation,nausea and vomiting were observed after the CSEA.The HR,MAP and Ramsay scores were recorded at the time of fixing anesthesia plane(T0),end of drug injection(T1),after 30 and 60 min of operation(T2 and T3) and end of operatiom(T4).Results: The differences of the shivering classification,and incidence of nausea and vomiting among group D,Z and C were statistically significant(P<0.05).The HR in group D and Z at T3 and T4 were less than those in group C(P<0.01).The differences of the MAP at T0 to T4 among the 3 groups were not statistically significant(P>0.05).The sedative effects in group D at T1 to T4 were better than that in group Z and C(P<0.01),and no excessive sedation was identified.Conclusions: The dexmedetomidine can effectively decrease the incidence of shivering after CSEA,has good sedative effect,and does not increase the incidence of postoperative adverse reaction,which is suitable for clinical application.
2016, 41(10): 1323-1325.
doi: 10.13898/j.cnki.issn.1000-2200.2016.10.020
Abstract:
Objective: To investigate the curative effects of compound Xuanju capsule combined with tadalafil in the treatment of diabetic erectile dysfunction(DMED).Methods: Ejghty patients with DMED were divided into the treatment group and control group.The treatment group and control group were treated with compound Xuanju capsule combined with tadalafil and single tadalafil,respectively.The patients were reexamined after 4 weeks of treatment.Results: The curative effects in treatment group were better than that in control group(P<0.05).The increasing degree of IIEF-5 score of the patients with moderate ED in treatment group after treatment was significantly higher than that in control group(P<0.01),while the differences of IIEF-5 score of the patients with mild and severe ED in two groups after treatment were not statistically significant(P>0.05).Conclusions: The treatment of DMED with compound Xuanju capsule combined with tadalafil has good effects and less adverse reaction.
Objective: To investigate the curative effects of compound Xuanju capsule combined with tadalafil in the treatment of diabetic erectile dysfunction(DMED).Methods: Ejghty patients with DMED were divided into the treatment group and control group.The treatment group and control group were treated with compound Xuanju capsule combined with tadalafil and single tadalafil,respectively.The patients were reexamined after 4 weeks of treatment.Results: The curative effects in treatment group were better than that in control group(P<0.05).The increasing degree of IIEF-5 score of the patients with moderate ED in treatment group after treatment was significantly higher than that in control group(P<0.01),while the differences of IIEF-5 score of the patients with mild and severe ED in two groups after treatment were not statistically significant(P>0.05).Conclusions: The treatment of DMED with compound Xuanju capsule combined with tadalafil has good effects and less adverse reaction.
2016, 41(10): 1334-1336.
doi: 10.13898/j.cnki.issn.1000-2200.2016.10.024
Abstract:
Objective: To observe the effects of Meridian Needling combined with proprioceptive neuromuscular facilitation in the treatment of peripheral facial paralysis.Methods: Sixty-two patients with peripheral facial paralysis were randomly divided into the treatment group(32 cases) and control group(30 cases).The control group and treatment group were treated with pure acupuncture and Meridian Needling combined with proprioceptive neuromuscular facilitation,respectively.The curative effects between two groups were compared.Results: The curative effect in treatment group was significantly better than that in control group(P<0.01).Conclusions: The treatment of peripheral facial paralysis with Meridian Needling combined with proprioceptive neuromuscular facilitation is an effective method.
Objective: To observe the effects of Meridian Needling combined with proprioceptive neuromuscular facilitation in the treatment of peripheral facial paralysis.Methods: Sixty-two patients with peripheral facial paralysis were randomly divided into the treatment group(32 cases) and control group(30 cases).The control group and treatment group were treated with pure acupuncture and Meridian Needling combined with proprioceptive neuromuscular facilitation,respectively.The curative effects between two groups were compared.Results: The curative effect in treatment group was significantly better than that in control group(P<0.01).Conclusions: The treatment of peripheral facial paralysis with Meridian Needling combined with proprioceptive neuromuscular facilitation is an effective method.
2016, 41(10): 1337-1339.
doi: 10.13898/j.cnki.issn.1000-2200.2016.10.025
Abstract:
Objective: To observe and analyze effect of Yindan Xinnaotong combined with aspirin on the hemorheology indexes in stroke patients.Methods: Eighty stroke patients were selected and randomly divided into the observation group(n=40) and the control group(n=40).The patients of the observation group were given Yindan Xinnaotong combined with aspirin,the patients of the control group were given conventional therapy.NIHSS score,MRS score,Barthel index and the related parameters of hemorheology were observed and compared before and after treatment in both groups,the clinical total effective rate of two groups of patients were compared.Results: Observation group of patients in the treatment of effective was significantly higher than control group(P<0.05),after treatment,the observation group of patients of NIHSS score and MRS score was significantly lower than control group(P<0.01),Barthel index was significantly higher than control group(P<0.05),the observation group of patients:the hemorheology indexes of red blood cells deposited,blood sedimentation,whole blood viscosity,plasma viscosity,blood sedimentation equation K value,whole blood reduction viscosity,fibrinogen were significantly lower than that of control group(P<0.05 to P<0.01).Conclusions: Yindan Xinnaotong combined with aspirin can significantly improve neural function and all the indexes of hemorheology in patients with stroke,worthy of clinical popularization and application.
Objective: To observe and analyze effect of Yindan Xinnaotong combined with aspirin on the hemorheology indexes in stroke patients.Methods: Eighty stroke patients were selected and randomly divided into the observation group(n=40) and the control group(n=40).The patients of the observation group were given Yindan Xinnaotong combined with aspirin,the patients of the control group were given conventional therapy.NIHSS score,MRS score,Barthel index and the related parameters of hemorheology were observed and compared before and after treatment in both groups,the clinical total effective rate of two groups of patients were compared.Results: Observation group of patients in the treatment of effective was significantly higher than control group(P<0.05),after treatment,the observation group of patients of NIHSS score and MRS score was significantly lower than control group(P<0.01),Barthel index was significantly higher than control group(P<0.05),the observation group of patients:the hemorheology indexes of red blood cells deposited,blood sedimentation,whole blood viscosity,plasma viscosity,blood sedimentation equation K value,whole blood reduction viscosity,fibrinogen were significantly lower than that of control group(P<0.05 to P<0.01).Conclusions: Yindan Xinnaotong combined with aspirin can significantly improve neural function and all the indexes of hemorheology in patients with stroke,worthy of clinical popularization and application.
2016, 41(10): 1340-1343.
doi: 10.13898/j.cnki.issn.1000-2200.2016.10.026
Abstract:
Objective: To investigate the causes and influencing factors of spontaneous abortion for providing the basis in formulating the control measures,guiding prepotency and maternal and child health care.Methods: Four hundred and eight patients with spontaneous abortion and 461 puerperas with normal pregnancy and labor were divided into the case group and control group according to the case-control study.The risk factors in two groups were investigated and analyzed.Results: One way ANOVA analysis showed that the age,profession,vaginal bleeding during pregnancy,family history of early pregnancy,pregnancy complications,folic acid application,pregnancy times and history of abnormal pregnancy were the influencing factors of spontaneous abortion(P<0.01).Multivariable logistic regression analysis showed that the age,clothing profession,chemical profession,beauty salon profession,building decoration profession,vaginal bleeding during pregnancy,family history of early pregnancy,folic acid use,reproductive tract infection,viral influenza,pregnancy times and history of abnormal pregnancy were the independent factor of spontaneous abortion.Conclusions: The age,clothing profession,chemical profession,beauty salon profession,building decoration profession,vaginal bleeding during pregnancy,family history of early pregnancy,infection during pregnancy,pregnancy times and history of abnormal pregnancy are the independent factors of spontaneous abortion,and the folic acid is a protective factor of spontaneous abortion.
Objective: To investigate the causes and influencing factors of spontaneous abortion for providing the basis in formulating the control measures,guiding prepotency and maternal and child health care.Methods: Four hundred and eight patients with spontaneous abortion and 461 puerperas with normal pregnancy and labor were divided into the case group and control group according to the case-control study.The risk factors in two groups were investigated and analyzed.Results: One way ANOVA analysis showed that the age,profession,vaginal bleeding during pregnancy,family history of early pregnancy,pregnancy complications,folic acid application,pregnancy times and history of abnormal pregnancy were the influencing factors of spontaneous abortion(P<0.01).Multivariable logistic regression analysis showed that the age,clothing profession,chemical profession,beauty salon profession,building decoration profession,vaginal bleeding during pregnancy,family history of early pregnancy,folic acid use,reproductive tract infection,viral influenza,pregnancy times and history of abnormal pregnancy were the independent factor of spontaneous abortion.Conclusions: The age,clothing profession,chemical profession,beauty salon profession,building decoration profession,vaginal bleeding during pregnancy,family history of early pregnancy,infection during pregnancy,pregnancy times and history of abnormal pregnancy are the independent factors of spontaneous abortion,and the folic acid is a protective factor of spontaneous abortion.
2016, 41(10): 1343-1346.
doi: 10.13898/j.cnki.issn.1000-2200.2016.10.027
Abstract:
Objective: To investigate the daily drinking water volume and its influencing factors,and provide the scientific reference in guiding drinking water in college students.Methods: A total of 450 students in a medical college were selected by stratified random sampling method.The drinking water status of medical college students were investigated using self-resigned questionnaire.Results: The median of daily drinking water volume of a medical college students was 880 mL,and the daily drinking water volume in male and female students were 920 mL and 860 mL,respectively.The active drinking water in 58.3% college students and thirsty drinking water in 41.7% college students were found.The differences of daily drinking water volume in students with different gender,exercise time,situation of drinking water and knowledge of nutrition were statistical significance(P<0.05 to P<0.01).The rate of drinking bottled water was 75.3%,which was influenced by gender,exercise time,knowledge of nutrition,smoking and drinking wine and monthly expenditure.Conclusions: Drinking water education should be strengthened,drinking bottled water should be reduced,and the healthy behavior of drinking water should be cultured.
Objective: To investigate the daily drinking water volume and its influencing factors,and provide the scientific reference in guiding drinking water in college students.Methods: A total of 450 students in a medical college were selected by stratified random sampling method.The drinking water status of medical college students were investigated using self-resigned questionnaire.Results: The median of daily drinking water volume of a medical college students was 880 mL,and the daily drinking water volume in male and female students were 920 mL and 860 mL,respectively.The active drinking water in 58.3% college students and thirsty drinking water in 41.7% college students were found.The differences of daily drinking water volume in students with different gender,exercise time,situation of drinking water and knowledge of nutrition were statistical significance(P<0.05 to P<0.01).The rate of drinking bottled water was 75.3%,which was influenced by gender,exercise time,knowledge of nutrition,smoking and drinking wine and monthly expenditure.Conclusions: Drinking water education should be strengthened,drinking bottled water should be reduced,and the healthy behavior of drinking water should be cultured.
2016, 41(10): 1350-1352.
doi: 10.13898/j.cnki.issn.1000-2200.2016.10.029
Abstract:
Objective: To evaluate the accuracy of mammography and color Doppler ultrasonography in the assessment of tumor size of breast cancer before operation.Methods: The tumor sizes in 70 patients with primary breast cancer before operation were measured using mammography and color Doppler ultrasonography,which was compared with the size of the tumor pathology after modified radical mastectomy.Results: The tumor size measured by mammography in premenopausal patients before operation was positive correlation with the postoperative breast cancer size measured by pathology(P<0.05),the tumor size measured by color Doppler ultrasonography in premenopausal patients before operation was not correlation with the postoperative breast cancer size measured by pathology(P>0.05).The tumor size measured by mammography and color Doppler ultrasonography in postmenopausal patients before operation were positive correlation with the postoperative breast cancer size measured by pathology(P<0.05 and P<0.01).The tumor sizes measured by mammography and color Doppler ultrasonography in patients without axillary lymph node metastasis before operation were positive correlation with the postoperative breast cancer size(P<0.01 and P<0.05).The tumor sizes measured by mammography and color Doppler ultrasonography in patients with axillary lymph node metastasis were not correlation with the postoperative breast cancer size(P>0.05).Excluding other clinical pathological factors,the tumor sizes measured by mammography and color Doppler ultrasonography before operation were positive correlation with the postoperative breast cancer size(P<0.01 and P<0.05).Conclusions: The accuracy of mammography in evaluating the tumor size of breast cancer is better than that of color Doppler ultrasonography.For some special structure and type breast,the accuracy of mammography in evaluating the tumor size still need to explore before operation.
Objective: To evaluate the accuracy of mammography and color Doppler ultrasonography in the assessment of tumor size of breast cancer before operation.Methods: The tumor sizes in 70 patients with primary breast cancer before operation were measured using mammography and color Doppler ultrasonography,which was compared with the size of the tumor pathology after modified radical mastectomy.Results: The tumor size measured by mammography in premenopausal patients before operation was positive correlation with the postoperative breast cancer size measured by pathology(P<0.05),the tumor size measured by color Doppler ultrasonography in premenopausal patients before operation was not correlation with the postoperative breast cancer size measured by pathology(P>0.05).The tumor size measured by mammography and color Doppler ultrasonography in postmenopausal patients before operation were positive correlation with the postoperative breast cancer size measured by pathology(P<0.05 and P<0.01).The tumor sizes measured by mammography and color Doppler ultrasonography in patients without axillary lymph node metastasis before operation were positive correlation with the postoperative breast cancer size(P<0.01 and P<0.05).The tumor sizes measured by mammography and color Doppler ultrasonography in patients with axillary lymph node metastasis were not correlation with the postoperative breast cancer size(P>0.05).Excluding other clinical pathological factors,the tumor sizes measured by mammography and color Doppler ultrasonography before operation were positive correlation with the postoperative breast cancer size(P<0.01 and P<0.05).Conclusions: The accuracy of mammography in evaluating the tumor size of breast cancer is better than that of color Doppler ultrasonography.For some special structure and type breast,the accuracy of mammography in evaluating the tumor size still need to explore before operation.
2016, 41(10): 1355-1357.
doi: 10.13898/j.cnki.issn.1000-2200.2016.10.031
Abstract:
Objective: To investigate the level of serum high sensitivity C reactive protein(hs-CRP) in schizophrenic,and effect of antipsychotic drugs on the level of hs-CRP.Methods: The serum levels of hs-CRP in the first onset 106 schizophrenia patients(the first onset group),108 patients treated with antipsychotic drugs(long-term medication group) and 137 healthy people(control group) were detected,the difference of which was compared.The serum levels of hs-CRP in patients treated with individual clozapine and risperidone were analyzed.The scores of the positive and negative syndrome scale(PANSS) in schizophrenia patients was investigated.Results: The serum level of hs-CRP in long-term medication group was significantly higher than that in control group(P<0.01),and the serum level of hs-CRP in long-term medication group was higher than that in the first onset group(P<0.05).The serum level of hs-CRP in clozapine group was significantly higher than that in risperidone group and the first onset group(P<0.01).The difference of the hs-CRP level between the risperidone group and first onset group was not statistically significant(P>0.05).The scores of the positive scale and negative scale of PANSS,general pathology scale and total score in schizophrenia patients with hs-CRP>2.066 4 mg/L were significantly higher than those in patients with hs-CRP<2.066 4 mg/L group(P<0.05 to P<0.01).Correlation analysis showed the expression of serum hs-CRPwas positively correlated with schizophrenia severity(P<0.05).Conclusions: The serum levels of hs-CRP in schizophrenia patients significantly increased,and the clozapine treatment can upregulate the serum level of hs-CRP.The level of hs-CRP is correlated with psychotic state.
Objective: To investigate the level of serum high sensitivity C reactive protein(hs-CRP) in schizophrenic,and effect of antipsychotic drugs on the level of hs-CRP.Methods: The serum levels of hs-CRP in the first onset 106 schizophrenia patients(the first onset group),108 patients treated with antipsychotic drugs(long-term medication group) and 137 healthy people(control group) were detected,the difference of which was compared.The serum levels of hs-CRP in patients treated with individual clozapine and risperidone were analyzed.The scores of the positive and negative syndrome scale(PANSS) in schizophrenia patients was investigated.Results: The serum level of hs-CRP in long-term medication group was significantly higher than that in control group(P<0.01),and the serum level of hs-CRP in long-term medication group was higher than that in the first onset group(P<0.05).The serum level of hs-CRP in clozapine group was significantly higher than that in risperidone group and the first onset group(P<0.01).The difference of the hs-CRP level between the risperidone group and first onset group was not statistically significant(P>0.05).The scores of the positive scale and negative scale of PANSS,general pathology scale and total score in schizophrenia patients with hs-CRP>2.066 4 mg/L were significantly higher than those in patients with hs-CRP<2.066 4 mg/L group(P<0.05 to P<0.01).Correlation analysis showed the expression of serum hs-CRPwas positively correlated with schizophrenia severity(P<0.05).Conclusions: The serum levels of hs-CRP in schizophrenia patients significantly increased,and the clozapine treatment can upregulate the serum level of hs-CRP.The level of hs-CRP is correlated with psychotic state.
2016, 41(10): 1358-1360.
doi: 10.13898/j.cnki.issn.1000-2200.2016.10.032
Abstract:
Objective: To study the drug sensitivity of L-forms of Pseudomonas aeruginosa(PA) to the third and forth generation cephalosporins.Methods: PA was induced into a stable L-form.The drug sensitivity of PA L-forms to the third and forth generation cephalosporins was analyzed by K-B drug sensitivity test.The change trend of drug sensitivity and resistance of PA L-forms was analyzed.Results: The inhibition zone of PA L-forms was smaller than that of their parent bacteria,and there had the significant difference(P<0.05).But the drug sensitivity of L-forms of PA to the third and forth generation cephalosporins was still sensitive.Conclusions: The drug sensitivity of PA L-forms to the third and forth generation cephalosporins is still sensitive.
Objective: To study the drug sensitivity of L-forms of Pseudomonas aeruginosa(PA) to the third and forth generation cephalosporins.Methods: PA was induced into a stable L-form.The drug sensitivity of PA L-forms to the third and forth generation cephalosporins was analyzed by K-B drug sensitivity test.The change trend of drug sensitivity and resistance of PA L-forms was analyzed.Results: The inhibition zone of PA L-forms was smaller than that of their parent bacteria,and there had the significant difference(P<0.05).But the drug sensitivity of L-forms of PA to the third and forth generation cephalosporins was still sensitive.Conclusions: The drug sensitivity of PA L-forms to the third and forth generation cephalosporins is still sensitive.
2016, 41(10): 1360-1362.
doi: 10.13898/j.cnki.issn.1000-2200.2016.10.033
Abstract:
Objective: To investigate the distribution and drug resistance of pathogens isolated from blood culture to provide the basis in clinical rational use of antibiotics.Methods: The data of the pathogens isolated from blood culture and results of drug sensitive test were retrospectively analyzed from July 2011 to June 2012.The blood was cultured using the BACT/ALERT 3D automatic blood culture instrument.The bacteria identification and drug sensitive test were implemented using ATB expression identification system.Results: Seventy-six strains of pathogenic bacteria were isolated from clinical blood culture samples,which included 41 strains of gram-positive bacteria(53.95%),31 strains of gram-negative bacteria(40.79%) and 4 strains of fungi(5.26%).The top five pathogens were the Coagulase-negative staphylococci,Escherichia coli,staphylococcus aureus,Klebsiella pneumonia and Pseudomonas aeruginosa by turn.The sensitive rate of Escherichia coli and Klebsiella penumonia to carbapenem drug was 100%,the gram-positive Cocci of vancomycin-resistant was not found.Conclusions: The timely monitoring of the pathogenic bacteria change in blood culture and trend of drug resistance are important in guiding the clinical drug use.
Objective: To investigate the distribution and drug resistance of pathogens isolated from blood culture to provide the basis in clinical rational use of antibiotics.Methods: The data of the pathogens isolated from blood culture and results of drug sensitive test were retrospectively analyzed from July 2011 to June 2012.The blood was cultured using the BACT/ALERT 3D automatic blood culture instrument.The bacteria identification and drug sensitive test were implemented using ATB expression identification system.Results: Seventy-six strains of pathogenic bacteria were isolated from clinical blood culture samples,which included 41 strains of gram-positive bacteria(53.95%),31 strains of gram-negative bacteria(40.79%) and 4 strains of fungi(5.26%).The top five pathogens were the Coagulase-negative staphylococci,Escherichia coli,staphylococcus aureus,Klebsiella pneumonia and Pseudomonas aeruginosa by turn.The sensitive rate of Escherichia coli and Klebsiella penumonia to carbapenem drug was 100%,the gram-positive Cocci of vancomycin-resistant was not found.Conclusions: The timely monitoring of the pathogenic bacteria change in blood culture and trend of drug resistance are important in guiding the clinical drug use.
2016, 41(10): 1363-1366.
doi: 10.13898/j.cnki.issn.1000-2200.2016.10.034
Abstract:
Objective: To observe the influences of Qili cardiac capsule on the liver,renal function and electrolyte levels in patients with chronic heart failure(CHF).Methods: Eighty-two patients with CHF were randomly divided into the control group(38 cases) and observation group(44 cases).The control group were treated with the routine treatment of digoxin,and the observation group were additionally treated with Qili cardiac capsule based on the control group.The treatment course in two groups was 4 weeks.The liver,renal function and electrolyte level between two groups were compared.Results: The clinical efficacy in observation group was better than that in control group(P<0.05).The differences of the renal function indexes(including creatinine,urea and uric acid) and electrolyte levels between two groups were not statistically significant(P>0.05).The levels of aspartate aminotransferase and total bile acid of liver function indexes and cystatin C,retinol-binding protein of renal function indexes in observation group were significantly higher than those in control group(P<0.01).The levels of albumin,prealbumin and calcium,sodium and chloride of electrolytes in observation group were lower than those in control group(P<0.05 to P<0.01).The liver,renal function and electrolyte levels in two groups were in normal scope.Conclusions: Based on the routine treatment,the curative effects of additional Qili cardiac capsule on CHF are good,which has certain effects on the liver,renal function and electrolyte levels,and no adverse effect.
Objective: To observe the influences of Qili cardiac capsule on the liver,renal function and electrolyte levels in patients with chronic heart failure(CHF).Methods: Eighty-two patients with CHF were randomly divided into the control group(38 cases) and observation group(44 cases).The control group were treated with the routine treatment of digoxin,and the observation group were additionally treated with Qili cardiac capsule based on the control group.The treatment course in two groups was 4 weeks.The liver,renal function and electrolyte level between two groups were compared.Results: The clinical efficacy in observation group was better than that in control group(P<0.05).The differences of the renal function indexes(including creatinine,urea and uric acid) and electrolyte levels between two groups were not statistically significant(P>0.05).The levels of aspartate aminotransferase and total bile acid of liver function indexes and cystatin C,retinol-binding protein of renal function indexes in observation group were significantly higher than those in control group(P<0.01).The levels of albumin,prealbumin and calcium,sodium and chloride of electrolytes in observation group were lower than those in control group(P<0.05 to P<0.01).The liver,renal function and electrolyte levels in two groups were in normal scope.Conclusions: Based on the routine treatment,the curative effects of additional Qili cardiac capsule on CHF are good,which has certain effects on the liver,renal function and electrolyte levels,and no adverse effect.
2016, 41(10): 1370-1372.
doi: 10.13898/j.cnki.issn.1000-2200.2016.10.036
Abstract:
Objective: To explore the effects of low temperature adjustable sodium dialysis mode on hypotension in middle-elderly patients.Methods: Ten hypotension for ≥2 times middle-elderly patients treated with regularly hemodialysis for continuous 4 times were divided into the standard group(treatment with standard dialysis mode) and low temperature group(treatment with low temperature adjustable sodium dialysis mode),and two groups were treated for 4 weeks,12 times each mode.The body temperature,heart rate,and blood pressure and heart rate at 30-minute intervals during the process of dialysis were monitored before and after dialysis.The times of hypotension,related symptoms and nurse intervention in two groups were recorded.Results: The incidence of hypotension and times of nurse intervention in low temperature group were significantly less than those in standard group(P<0.01).During and after dialysis,the systolic and diastolic pressure in low temperature group were obviously higher than those in standard group(P<0.01).Conclusions: Lower temperature adjustable sodium dialysis can effectively reduce the occurrence of hypotension,and improve the tolerance to dialysis in middle-elderly patients,which is a safe and effective therapy.
Objective: To explore the effects of low temperature adjustable sodium dialysis mode on hypotension in middle-elderly patients.Methods: Ten hypotension for ≥2 times middle-elderly patients treated with regularly hemodialysis for continuous 4 times were divided into the standard group(treatment with standard dialysis mode) and low temperature group(treatment with low temperature adjustable sodium dialysis mode),and two groups were treated for 4 weeks,12 times each mode.The body temperature,heart rate,and blood pressure and heart rate at 30-minute intervals during the process of dialysis were monitored before and after dialysis.The times of hypotension,related symptoms and nurse intervention in two groups were recorded.Results: The incidence of hypotension and times of nurse intervention in low temperature group were significantly less than those in standard group(P<0.01).During and after dialysis,the systolic and diastolic pressure in low temperature group were obviously higher than those in standard group(P<0.01).Conclusions: Lower temperature adjustable sodium dialysis can effectively reduce the occurrence of hypotension,and improve the tolerance to dialysis in middle-elderly patients,which is a safe and effective therapy.
2016, 41(10): 1373-1374.
doi: 10.13898/j.cnki.issn.1000-2200.2016.10.037
Abstract:
Objective: To explore the related factors of the postoperative infection in breast surgery and its countermeasures.Methods: The clinical data of 362 patients treated with breast surgery were retrospectively analyzed.The independent risk factors of the postoperative infection were screened using logistic regression analysis,and the effective countermeasures were implemented.Results: Among 362 patients,the postoperative infection in 8 cases were found,the infection rate of which was 2.2%.Logistic regression analysis showed that breast surgery type,operation time,and povidone iodine cleaning wound were the independent risk factor of postoperative infection(P<0.05).Conclusions: Strengthening the clinician skill and specifying the postoperative nursing process can significantly reduce the postoperative infection rate of breast.
Objective: To explore the related factors of the postoperative infection in breast surgery and its countermeasures.Methods: The clinical data of 362 patients treated with breast surgery were retrospectively analyzed.The independent risk factors of the postoperative infection were screened using logistic regression analysis,and the effective countermeasures were implemented.Results: Among 362 patients,the postoperative infection in 8 cases were found,the infection rate of which was 2.2%.Logistic regression analysis showed that breast surgery type,operation time,and povidone iodine cleaning wound were the independent risk factor of postoperative infection(P<0.05).Conclusions: Strengthening the clinician skill and specifying the postoperative nursing process can significantly reduce the postoperative infection rate of breast.
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