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2009 Vol. 34, No. 7
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2009, 34(7): 553-555.
Abstract:
Objective: To observe the influence of linear alkylbenzenesulfonate(LAS) on the reproductive capacity of drosophila melanogaster,and the antagonism of isoflavone on the outcome.Methods: The reproductive capacity of the drosophila receiving different doses of LAS was detected;the antagonism of isoflavone and the interaction between isoflavone and LAS were observed using analysis of variance of factorial design.Results: The number of drosophila melanogaster of the three groups(with a dose of LAS 150 mg/kg,300 mg/kg and 600 mg/kg) was lower than that of control group(P<0.01) with a percentage of 85.07%,84.59% and 71.88%,respectively.The principal effect of soflavone had statistical significance(P=0.01),which demonstrated that isoflavone could protect drosophila melanogaster from the harm induced by LAS,but the main effect of LAS and the interaction between isoflavone and LAS were not found(P>0.05).Conclusions: LAS can degrade the reproductive capacity of drosophila melanogaster,and isoflavone can antagonize this effect.
Objective: To observe the influence of linear alkylbenzenesulfonate(LAS) on the reproductive capacity of drosophila melanogaster,and the antagonism of isoflavone on the outcome.Methods: The reproductive capacity of the drosophila receiving different doses of LAS was detected;the antagonism of isoflavone and the interaction between isoflavone and LAS were observed using analysis of variance of factorial design.Results: The number of drosophila melanogaster of the three groups(with a dose of LAS 150 mg/kg,300 mg/kg and 600 mg/kg) was lower than that of control group(P<0.01) with a percentage of 85.07%,84.59% and 71.88%,respectively.The principal effect of soflavone had statistical significance(P=0.01),which demonstrated that isoflavone could protect drosophila melanogaster from the harm induced by LAS,but the main effect of LAS and the interaction between isoflavone and LAS were not found(P>0.05).Conclusions: LAS can degrade the reproductive capacity of drosophila melanogaster,and isoflavone can antagonize this effect.
2009, 34(7): 555-557.
Abstract:
Objective: To establish the model of mandibular distraction osteogenesis in rabbits.Methods: Thirty white New Zealand rabbits underwent osteotomy in the right mandible.The bone stumps were repositioned and fixed with self-devised distraction equipment.After 7 days' latency period,the distraction was carried out,and the specimens were performed histology examination.Results: All the rabbits survived and were in good condition within the experiment period.The right mandible of all the rabbits was lengthened 3 mm successfully.Conclusions: Self-devised distraction equipment may be used for animal experiment,and rabbits can be established as an experimental model for study of distraction osteogenesis.
Objective: To establish the model of mandibular distraction osteogenesis in rabbits.Methods: Thirty white New Zealand rabbits underwent osteotomy in the right mandible.The bone stumps were repositioned and fixed with self-devised distraction equipment.After 7 days' latency period,the distraction was carried out,and the specimens were performed histology examination.Results: All the rabbits survived and were in good condition within the experiment period.The right mandible of all the rabbits was lengthened 3 mm successfully.Conclusions: Self-devised distraction equipment may be used for animal experiment,and rabbits can be established as an experimental model for study of distraction osteogenesis.
2009, 34(7): 558-562.
Abstract:
Objective: To explore the influence of neuronal nitric oxide synthase(nNOS) and inducible nitric oxide synthase(iNOS) on the spatial learning ability and memory of rats following traumatic brain injury(TBI),and to observe the curative effect of 7-nitroindazole(7-NI) and aminoguanidine(AG).Methods: Two hundred and fifty male Wistar rats were randomly divided into 5 groups.Severe closed brain injury models were made according to Marmarou;immunohistochemical staining was used to detect the expression of nNOS and iNOS in the hippocampus CA1 region of the rats;TUNEL in situ was applied in determination of the apoptosis cells in the hippocampus CA1 region;the spatical learning ability and memory of the rats after injury was measured by means of Morris Water maze.Results: nNOS and iNOS expressed significantly in the hippocampus CA1 region of the rats.nNOS immuno-reactivity peaked at 6hr after injury(P<0.05),iNOS peaked at 3 days after injury(P<0.05),and TUNEL positive cells peaked at 3 days after injury(P<0.05).The number of positive cells decreased significantly 6 hours after injury in the treatment groups compared with that in the trauma group(P<0.05).And 3 days after injury,positive cells decreased in all the three groups,with the combination therapy group the most obvious.Conclusions: The decrease of learning and memorizing ability of the rats after TBI is associated with the nerve toxicity of NOS.7-NI and AG protect the nerve by inhibiting the activity and expression of nNOS and iNOS,which may improve the spatial learning ability and memory of rats.
Objective: To explore the influence of neuronal nitric oxide synthase(nNOS) and inducible nitric oxide synthase(iNOS) on the spatial learning ability and memory of rats following traumatic brain injury(TBI),and to observe the curative effect of 7-nitroindazole(7-NI) and aminoguanidine(AG).Methods: Two hundred and fifty male Wistar rats were randomly divided into 5 groups.Severe closed brain injury models were made according to Marmarou;immunohistochemical staining was used to detect the expression of nNOS and iNOS in the hippocampus CA1 region of the rats;TUNEL in situ was applied in determination of the apoptosis cells in the hippocampus CA1 region;the spatical learning ability and memory of the rats after injury was measured by means of Morris Water maze.Results: nNOS and iNOS expressed significantly in the hippocampus CA1 region of the rats.nNOS immuno-reactivity peaked at 6hr after injury(P<0.05),iNOS peaked at 3 days after injury(P<0.05),and TUNEL positive cells peaked at 3 days after injury(P<0.05).The number of positive cells decreased significantly 6 hours after injury in the treatment groups compared with that in the trauma group(P<0.05).And 3 days after injury,positive cells decreased in all the three groups,with the combination therapy group the most obvious.Conclusions: The decrease of learning and memorizing ability of the rats after TBI is associated with the nerve toxicity of NOS.7-NI and AG protect the nerve by inhibiting the activity and expression of nNOS and iNOS,which may improve the spatial learning ability and memory of rats.
2009, 34(7): 563-565.
Abstract:
Objective: To investigate the anti-tumor activities of pyrazole derivatives against PC3,Bcap37 and BGC823 cells,and the mechanism of action.Methods: The inhibition effects of pyrazole derivatives on PC3,Bcap37 and BGC823 cells in vitro were tested through MTT colorimetric assay and the apoptotic morphology was observed by staining the PC3 cells with AO/EB.The inhibition effects of the compounds on the phosphorylation of Erk1/2 were determined by Western Blot analysis.Results: Pyrazole derivatives showed inhibition activities against PC3,Bcap37 and BGC823 cells in a concentration dependent manner;compound F could induce the apoptosis of PC3 and Bcap37 cells;Western Blot analysis showed that pyrazole derivatives could not inhibit the phosphorylation of Erk1/2 induced by EGF.Conclusions: Pyrazole derivatives can inhibit the activities of PC3,Bcap37 and BGC823 cells,and compound F may induce the apoptosis of PC3 and Bcap37 cells;pyrazole derivatives can not inhibit the proliferation of PC3 cell through Erk1/2 mediated signal pathway.
Objective: To investigate the anti-tumor activities of pyrazole derivatives against PC3,Bcap37 and BGC823 cells,and the mechanism of action.Methods: The inhibition effects of pyrazole derivatives on PC3,Bcap37 and BGC823 cells in vitro were tested through MTT colorimetric assay and the apoptotic morphology was observed by staining the PC3 cells with AO/EB.The inhibition effects of the compounds on the phosphorylation of Erk1/2 were determined by Western Blot analysis.Results: Pyrazole derivatives showed inhibition activities against PC3,Bcap37 and BGC823 cells in a concentration dependent manner;compound F could induce the apoptosis of PC3 and Bcap37 cells;Western Blot analysis showed that pyrazole derivatives could not inhibit the phosphorylation of Erk1/2 induced by EGF.Conclusions: Pyrazole derivatives can inhibit the activities of PC3,Bcap37 and BGC823 cells,and compound F may induce the apoptosis of PC3 and Bcap37 cells;pyrazole derivatives can not inhibit the proliferation of PC3 cell through Erk1/2 mediated signal pathway.
2009, 34(7): 566-567.
Abstract:
Objective: To assess the value of fibrobronchoscopy in diagnosis of atelectasis.Methods: Five hundred and ninety patients with atelectasis confirmed by X-rays and computed chest tomograms(CT) were examined by fibrobronchoscopy,and the causes of disease,the features of fibrobronchoscopy,the location and age of the patients were analyzed.Results: Of the 590 cases,lung cancer accounted for 428,chronic inflammation was observed in 133 cases,tuberculosis in 21 cases,foreign bodies in 5 cases,aspergillus in 2 cases and lymphoma in 1 case.Conclusions: Fibrobronchoscopy is an important means in pathological diagnosis of atelectasis.Patients with atelectasis should resort to fibrobronchoscopy as early as possible.
Objective: To assess the value of fibrobronchoscopy in diagnosis of atelectasis.Methods: Five hundred and ninety patients with atelectasis confirmed by X-rays and computed chest tomograms(CT) were examined by fibrobronchoscopy,and the causes of disease,the features of fibrobronchoscopy,the location and age of the patients were analyzed.Results: Of the 590 cases,lung cancer accounted for 428,chronic inflammation was observed in 133 cases,tuberculosis in 21 cases,foreign bodies in 5 cases,aspergillus in 2 cases and lymphoma in 1 case.Conclusions: Fibrobronchoscopy is an important means in pathological diagnosis of atelectasis.Patients with atelectasis should resort to fibrobronchoscopy as early as possible.
2009, 34(7): 568-570.
Abstract:
Objective: To analyze the reasons for total hip arthroplasties revision,and to evaluate the results.Methods: Eighteen cases(18 hips) with loosened hip prosthesis were revised.The primary hip arthroplasty included femoral head replacement(3 cases) and total hip replacement(15 cases).The reasons for revision were aseptic loosening(14 cases),acetabular erosion(2 cases),infection(1 case) and femur prosthesis failure(1 case).Results: The follow-up lasted from 6 months to 4 years.The successful rate of revision was 84%.Conclusions: The most common reason for revision is aseptic loosening,and the results of revision of total hip arthroplasty are satisfactory.
Objective: To analyze the reasons for total hip arthroplasties revision,and to evaluate the results.Methods: Eighteen cases(18 hips) with loosened hip prosthesis were revised.The primary hip arthroplasty included femoral head replacement(3 cases) and total hip replacement(15 cases).The reasons for revision were aseptic loosening(14 cases),acetabular erosion(2 cases),infection(1 case) and femur prosthesis failure(1 case).Results: The follow-up lasted from 6 months to 4 years.The successful rate of revision was 84%.Conclusions: The most common reason for revision is aseptic loosening,and the results of revision of total hip arthroplasty are satisfactory.
2009, 34(7): 570-572.
Abstract:
Objective: To evaluate the effect of ω-3 fatty acids(PUFA) supplemented total parenteral nutrition(TPN) support on critical patients with closed abdominal injury.Methods: Twenty three critical patients which were diagnosed with systemic inflammation response syndrome(SIRS) with closed abdominal injury were randomly divided into PUFA group and control group.All patients were treated with routine treatment combined with TPN for 5 days.The parameters including blood routine test,hepatic and renal functions indexes and serum C-reactive protein were measured one day before TPN and at the end of the fifth day.Acute physiology and chronic health evaluationⅡ(APACHEⅡ) was also analyzed.Results: The level of serum C-reactive protein and the scores of APACHE Ⅱ were decreased significantly in these two groups,while the level of platelet and albumin were increased significantly(P<0.01).The changes of these parameters in PUFA group were more obvious than those in control group(P< 0.05).Conclusions: ω-3 fatty acids supplemented TPN can inhibit the degree of acute inflammatory response of critical patients with closed abdominal injury and improve the prognosis.
Objective: To evaluate the effect of ω-3 fatty acids(PUFA) supplemented total parenteral nutrition(TPN) support on critical patients with closed abdominal injury.Methods: Twenty three critical patients which were diagnosed with systemic inflammation response syndrome(SIRS) with closed abdominal injury were randomly divided into PUFA group and control group.All patients were treated with routine treatment combined with TPN for 5 days.The parameters including blood routine test,hepatic and renal functions indexes and serum C-reactive protein were measured one day before TPN and at the end of the fifth day.Acute physiology and chronic health evaluationⅡ(APACHEⅡ) was also analyzed.Results: The level of serum C-reactive protein and the scores of APACHE Ⅱ were decreased significantly in these two groups,while the level of platelet and albumin were increased significantly(P<0.01).The changes of these parameters in PUFA group were more obvious than those in control group(P< 0.05).Conclusions: ω-3 fatty acids supplemented TPN can inhibit the degree of acute inflammatory response of critical patients with closed abdominal injury and improve the prognosis.
2009, 34(7): 573-576.
Abstract:
Objective: To study the clinical and histo pathological features,diagnosis,differential diagnosis and treatment of minimal deviation adenocarcinoma(MDA) of cervix.Methods: The clinical data of two cases of MDA were collected.Histopathological examination was performed and the literature related was reviewed.Results: The main clinical symptoms of MDA were watery leucorrhea,and large and hard cervix.It was often misdiagnosed by biopsy.There were many irregular microcysts in the cervix wall,and the cervix wall was hypertrophic.The pathological findings showed hyperplasia of the glands,which were irregular,twisted and cystic,feeling like chicken claw.Invasion was often observed around the vessels and the nervous tissues.The prognosis of the two cases was very poor.Conclusions: MDA is a kind of malignant adenoma of cervix with little dysplasia in cytology.MDA is very difficult to diagnose with cytological examination and biopsy,and is often misdiagnosed as benign tumor,but has a malignant biological behavior.
Objective: To study the clinical and histo pathological features,diagnosis,differential diagnosis and treatment of minimal deviation adenocarcinoma(MDA) of cervix.Methods: The clinical data of two cases of MDA were collected.Histopathological examination was performed and the literature related was reviewed.Results: The main clinical symptoms of MDA were watery leucorrhea,and large and hard cervix.It was often misdiagnosed by biopsy.There were many irregular microcysts in the cervix wall,and the cervix wall was hypertrophic.The pathological findings showed hyperplasia of the glands,which were irregular,twisted and cystic,feeling like chicken claw.Invasion was often observed around the vessels and the nervous tissues.The prognosis of the two cases was very poor.Conclusions: MDA is a kind of malignant adenoma of cervix with little dysplasia in cytology.MDA is very difficult to diagnose with cytological examination and biopsy,and is often misdiagnosed as benign tumor,but has a malignant biological behavior.
2009, 34(7): 576-578.
Abstract:
Objective: To investigate the relationship between the expressions of ezrin protein and the invasion and metastasis of esophageal squamous cell carcinoma(ESCC).Methods: The expression of ezrin protein in 76 cases of ESCC and 30 cases of normal esophageal squamous epithelia was detected by using S-P method of immunohistochemical staining,and the results were analyzed with reference to the clinicopathological features.Results: The abnormal expression rates of ezrin protein in ESCC and normal esophageal squamous epithelia were 78.95%(60/76) and 26.67%(8/30),respectively(P<0.01).The abnormal expression of ezrin protein was related to the cell differentiation degree and lymph node metastasis(P<0.05 and P<0.01) in 76 cases of ESCC.Conclusions: The expression of ezrin protein is up-regulated in ESCC,and the overexpression is related to the cell differentiation degree and lymph node metastasis.
Objective: To investigate the relationship between the expressions of ezrin protein and the invasion and metastasis of esophageal squamous cell carcinoma(ESCC).Methods: The expression of ezrin protein in 76 cases of ESCC and 30 cases of normal esophageal squamous epithelia was detected by using S-P method of immunohistochemical staining,and the results were analyzed with reference to the clinicopathological features.Results: The abnormal expression rates of ezrin protein in ESCC and normal esophageal squamous epithelia were 78.95%(60/76) and 26.67%(8/30),respectively(P<0.01).The abnormal expression of ezrin protein was related to the cell differentiation degree and lymph node metastasis(P<0.05 and P<0.01) in 76 cases of ESCC.Conclusions: The expression of ezrin protein is up-regulated in ESCC,and the overexpression is related to the cell differentiation degree and lymph node metastasis.
2009, 34(7): 579-581.
Abstract:
Objective: To investigate the expression and clinical significance of KiSS-1 gene in nasopharyngeal carcinoma(NPC) tissue.Methods: KiSS-1 mRNA expression level was detected in 31 nasopharyngeal carcinoma tissues and 14 non-tumorous tissues by reverse transcription polymerase chain reaction(RT-PCR).The relationship between NPC and clinicopathological factors was also be analyzed.Results: The positive rate of KiSS-1 mRNA in nasopharyngeal carcinoma and non-tumorous nasopharyngeal tissues was 67.7% and 85.7%,respectively.The result was no significant difference between these two groups(P>0.05).No correlation was found between the expression of KiSS-1 gene and other clinicopathological factors such as patient's sex,age,T stage(P>0.05).Conclusions: KiSS-1 gene is highly expressed in non-tumorous nasopharyngeal tissue while low expressed in NPC.Loss of KiSS-1 expression was correlated with clinical stage and lymph node metastasis of NPC.These inclicated that KiSS-1 may play an important role in metastasis of NPC.
Objective: To investigate the expression and clinical significance of KiSS-1 gene in nasopharyngeal carcinoma(NPC) tissue.Methods: KiSS-1 mRNA expression level was detected in 31 nasopharyngeal carcinoma tissues and 14 non-tumorous tissues by reverse transcription polymerase chain reaction(RT-PCR).The relationship between NPC and clinicopathological factors was also be analyzed.Results: The positive rate of KiSS-1 mRNA in nasopharyngeal carcinoma and non-tumorous nasopharyngeal tissues was 67.7% and 85.7%,respectively.The result was no significant difference between these two groups(P>0.05).No correlation was found between the expression of KiSS-1 gene and other clinicopathological factors such as patient's sex,age,T stage(P>0.05).Conclusions: KiSS-1 gene is highly expressed in non-tumorous nasopharyngeal tissue while low expressed in NPC.Loss of KiSS-1 expression was correlated with clinical stage and lymph node metastasis of NPC.These inclicated that KiSS-1 may play an important role in metastasis of NPC.
2009, 34(7): 582-584.
Abstract:
Objective: To evaluate the therapy of inhaling nebulized budesonide suspension combined with terbutaline sulphate for treatment of chronic obstructive pulmonary disease(AECOPD) at acute exacerbations phase.Methods: Sixty-five patients with AECOPD were randomly divided into observed group(33 cases) and control group(32 cases).Both groups were administered the therapy of oxygen inhalation,anti-infection and intravenous aminophylline.On the basis of routine therapy,the patients in the observed group were given nebulized budesonide suspension inhalation and terbutaline sulphate,and the control group were ministered only terbutaline sulphate inhalation;then the clinical manifestation,blood gas analysis,and FEV1% at baseline and 7-10 days after treatment were determined.Results: The PaO2,PaCO2 and FEV1% were significantly different in the treatment group before and after the therapy(P<0.01).The response rate was 90.9% and 68.8% in the observed group and the control group respectively(P>0.05).The difference was not significant.Conclusions: The therapy of inhaling nebulized budesonide suspension combing with terbutaline sulphate aerosol may effectively relieve the symptoms of AECOPD.It's the choice therapy for AECOPD.
Objective: To evaluate the therapy of inhaling nebulized budesonide suspension combined with terbutaline sulphate for treatment of chronic obstructive pulmonary disease(AECOPD) at acute exacerbations phase.Methods: Sixty-five patients with AECOPD were randomly divided into observed group(33 cases) and control group(32 cases).Both groups were administered the therapy of oxygen inhalation,anti-infection and intravenous aminophylline.On the basis of routine therapy,the patients in the observed group were given nebulized budesonide suspension inhalation and terbutaline sulphate,and the control group were ministered only terbutaline sulphate inhalation;then the clinical manifestation,blood gas analysis,and FEV1% at baseline and 7-10 days after treatment were determined.Results: The PaO2,PaCO2 and FEV1% were significantly different in the treatment group before and after the therapy(P<0.01).The response rate was 90.9% and 68.8% in the observed group and the control group respectively(P>0.05).The difference was not significant.Conclusions: The therapy of inhaling nebulized budesonide suspension combing with terbutaline sulphate aerosol may effectively relieve the symptoms of AECOPD.It's the choice therapy for AECOPD.
2009, 34(7): 584-587.
Abstract:
Objective: To investigate the significance of the expression of stat-3 and survivin in the genesis and development of breast carcinoma.Methods: Immunohistochemistry S-P was utilized to measure the expression of stat-3 and survivin protein in 51 breast carcinoma tissues and 25 adjacent noncarcerous tissues.Results: The expression of stat-3 protein was higher in breast carcinoma tissues than that in the adjacent noncarcerous tissues(P<0.001);the expression of stat-3 protein was higher in the positive lymph node group than in the negative lymph node group(P<0.05).It was not related to the patients' age,size of tumor,pathological grades,clinical stages,ER,PR or cerbB-2(P>0.05).The expression of survivin protein was higer in breast carcinoma tissues than in the adjacent noncarcerous tissues,and the difference was significant(P<0.001).The expression of survivin protein had no significant coorelation with the patients'age,size of tumor,pathological grades,clinical stages,lymph node metastasis,ER,PR or cerbB-2(P>0.05).Of the 35 cases with positive survivin protein expression,positive stat-3 protein was detected in 34 of them.The expression of survivin and stat-3 had positive correlation in breast carcinoma(P<0.05).Conclusions: stat-3 and survivin may play an important role in the carcinogensis and progression of breast carcinoma by inhibiting apoptosis.
Objective: To investigate the significance of the expression of stat-3 and survivin in the genesis and development of breast carcinoma.Methods: Immunohistochemistry S-P was utilized to measure the expression of stat-3 and survivin protein in 51 breast carcinoma tissues and 25 adjacent noncarcerous tissues.Results: The expression of stat-3 protein was higher in breast carcinoma tissues than that in the adjacent noncarcerous tissues(P<0.001);the expression of stat-3 protein was higher in the positive lymph node group than in the negative lymph node group(P<0.05).It was not related to the patients' age,size of tumor,pathological grades,clinical stages,ER,PR or cerbB-2(P>0.05).The expression of survivin protein was higer in breast carcinoma tissues than in the adjacent noncarcerous tissues,and the difference was significant(P<0.001).The expression of survivin protein had no significant coorelation with the patients'age,size of tumor,pathological grades,clinical stages,lymph node metastasis,ER,PR or cerbB-2(P>0.05).Of the 35 cases with positive survivin protein expression,positive stat-3 protein was detected in 34 of them.The expression of survivin and stat-3 had positive correlation in breast carcinoma(P<0.05).Conclusions: stat-3 and survivin may play an important role in the carcinogensis and progression of breast carcinoma by inhibiting apoptosis.
2009, 34(7): 588-589.
Abstract:
Objective: To investigate the diagnostic value of changes of leukocyte count in patients with acute myocardial infarction(AMI).Methods: A total of 47 patients with AMI were selected according to the following standards:the chest pain lasted for no more than 2 hours,the myoglobin(Mb) was negative,and no one had diseases related to inflammation.The blood samples were obtained respectively at the time of onset,4-8 h and 12-24 h after the chest pain.And the leukocyte-reactive protein,cardiac troponin I(cTNI) and Mb were detected.All the patients were followed up for 3-12 months.During this period,their WBC was examined for three times,and the mean value was compared with that of the autoleukocyte controls as well as that of the normal control.Results: Within 2 hours of the onset of chest pain and with the Mb still negative,the leukocyte count in the AMI patients began to rise(9.12±2.18) ×109/L,which was higher than that of the autoleukocyte controls(6.49±1.09) ×109/L and the normal control(5.97±1.24) ×109/L(P<0.01).But neutrophil percentage presented no significant difference between AMI patients and the autoleukocyte controls at the time of onset(P>0.05).There was no significant difference in C reactive protein(CRP) levels between AMI patients and the normal control at the time of onset(P>0.05).The levels of WBC and CRP in AMI patients increased significantly after Mb and cTNI became positive(P<0.01),and reached their peak at 12-24 hours after the onset of chest pain.At the same time neutrophil percentage increased significantly,too(P<0.01).Conclusions: The white cell count begins to rise significantly at the onset of acute myocardial infarction when the Mb and cTNI are still negative.So the increase of leukocyte count is one of the early symptoms of AMI.
Objective: To investigate the diagnostic value of changes of leukocyte count in patients with acute myocardial infarction(AMI).Methods: A total of 47 patients with AMI were selected according to the following standards:the chest pain lasted for no more than 2 hours,the myoglobin(Mb) was negative,and no one had diseases related to inflammation.The blood samples were obtained respectively at the time of onset,4-8 h and 12-24 h after the chest pain.And the leukocyte-reactive protein,cardiac troponin I(cTNI) and Mb were detected.All the patients were followed up for 3-12 months.During this period,their WBC was examined for three times,and the mean value was compared with that of the autoleukocyte controls as well as that of the normal control.Results: Within 2 hours of the onset of chest pain and with the Mb still negative,the leukocyte count in the AMI patients began to rise(9.12±2.18) ×109/L,which was higher than that of the autoleukocyte controls(6.49±1.09) ×109/L and the normal control(5.97±1.24) ×109/L(P<0.01).But neutrophil percentage presented no significant difference between AMI patients and the autoleukocyte controls at the time of onset(P>0.05).There was no significant difference in C reactive protein(CRP) levels between AMI patients and the normal control at the time of onset(P>0.05).The levels of WBC and CRP in AMI patients increased significantly after Mb and cTNI became positive(P<0.01),and reached their peak at 12-24 hours after the onset of chest pain.At the same time neutrophil percentage increased significantly,too(P<0.01).Conclusions: The white cell count begins to rise significantly at the onset of acute myocardial infarction when the Mb and cTNI are still negative.So the increase of leukocyte count is one of the early symptoms of AMI.
2009, 34(7): 590-592.
Abstract:
Objective: To explore the surgical methods and curative efficacy of the standard large trauma craniectomy on severe traumatic brain injured patients.Methods: The clinical data and efficacy of standard large trauma craniectomy in 24 patients on severe brain trauma from January 2005 to January 2008 were retrospectively analyzed.Results: There were 20 patients who were survived in 24 patients,accounting for 83.3%.Four patients were died,the death rate was 16.7%.A follow-up of more than 12 months were conducted in the 20 survived patients according to the activity of daily living(ADL) grading system,these patients who belongs to grade Ⅰ,grade Ⅱ,grade Ⅲ,grade Ⅳ,and grade Ⅴ were 9,7,2,1 and 1 respectively.Conclusions: The curative efficacy of standdard large trauma craniectomy on severe brain trauma is good.
Objective: To explore the surgical methods and curative efficacy of the standard large trauma craniectomy on severe traumatic brain injured patients.Methods: The clinical data and efficacy of standard large trauma craniectomy in 24 patients on severe brain trauma from January 2005 to January 2008 were retrospectively analyzed.Results: There were 20 patients who were survived in 24 patients,accounting for 83.3%.Four patients were died,the death rate was 16.7%.A follow-up of more than 12 months were conducted in the 20 survived patients according to the activity of daily living(ADL) grading system,these patients who belongs to grade Ⅰ,grade Ⅱ,grade Ⅲ,grade Ⅳ,and grade Ⅴ were 9,7,2,1 and 1 respectively.Conclusions: The curative efficacy of standdard large trauma craniectomy on severe brain trauma is good.
2009, 34(7): 592-593.
Abstract:
Objective: To explore the effective treatment program for cerebellar hemorrhage.Methods: One hundred and sixty-two cases of cerebellar hemorrhage were studied retrospectively,of whom 96 cases were treated by medicine and the other six were received surgical operation.Results: Of the 102 cases,91 were survived and the other 11 patients were died.Conclusions: For the patients of cerebellar hemorrhage with a mild symptom who are not in a coma,conservative treatment with medicine is safe,whereas for those patients whose conditions deteriorate and whose consciousness becomes blurred,the emergency operation must be taken.
Objective: To explore the effective treatment program for cerebellar hemorrhage.Methods: One hundred and sixty-two cases of cerebellar hemorrhage were studied retrospectively,of whom 96 cases were treated by medicine and the other six were received surgical operation.Results: Of the 102 cases,91 were survived and the other 11 patients were died.Conclusions: For the patients of cerebellar hemorrhage with a mild symptom who are not in a coma,conservative treatment with medicine is safe,whereas for those patients whose conditions deteriorate and whose consciousness becomes blurred,the emergency operation must be taken.
2009, 34(7): 594-595.
Abstract:
Objective: To summarize and analyze the clinical diagnosis and treatment features for patients with gastric remnant carcinoma,as well as the factors which influence the prognosis of gastric remnant carcinoma.Methods: Twenty three cases with gastric remnant carcinoma were conducted with radical surgical resection,14 cases were conducted with palliative surgical resection,2 cases were conducted with exploratory laparotomy.The surgical methods and postoperative survival rate were summarized.Results: There was no operative mortality in this group,and from these cases,the surgical resection rate was 76.5%.In these cases who were treated with radical surgery,the postoperative 5-year survival rate was 22.5%,2-year survival rate was 63%;while these cases with non-radical surgery,the postoperative 5-year survival rate was 0,2-year survival rate was 58%.Conclusions: Fiberoptic gastroscope is needed for treatment of gastric remnant carcinoma;and the periodical gastroscope examination,early diagnosis and radical surgical treatment might be the key factors for gastric remnant carcinoma.
Objective: To summarize and analyze the clinical diagnosis and treatment features for patients with gastric remnant carcinoma,as well as the factors which influence the prognosis of gastric remnant carcinoma.Methods: Twenty three cases with gastric remnant carcinoma were conducted with radical surgical resection,14 cases were conducted with palliative surgical resection,2 cases were conducted with exploratory laparotomy.The surgical methods and postoperative survival rate were summarized.Results: There was no operative mortality in this group,and from these cases,the surgical resection rate was 76.5%.In these cases who were treated with radical surgery,the postoperative 5-year survival rate was 22.5%,2-year survival rate was 63%;while these cases with non-radical surgery,the postoperative 5-year survival rate was 0,2-year survival rate was 58%.Conclusions: Fiberoptic gastroscope is needed for treatment of gastric remnant carcinoma;and the periodical gastroscope examination,early diagnosis and radical surgical treatment might be the key factors for gastric remnant carcinoma.
2009, 34(7): 596-598.
Abstract:
Objective: To investigate the relation between the expression of bcl-2 and p53 in gastrointestinal stromal tumors(GIST).Methods: The expression of bcl-2 and p53 was detected in 53 cases of GIST by immunohistochemical technique,and the data was analyzed statistically.Results: The expression of bcl-2 and p53 in GIST was not significantlt different between the male and the female(P>0.05);There was no statistical significance between diameter and karyomitosis of GIST in these cases(P>0.05);There was no statistical significance between the expression of p53 and the malignancy of the GIST(P>0.05);There was statistical significance between the expression rate of bcl-2 and the malignancy of the GIST(P<0.01);There was statistical significance between the expression level of bcl-2 and the malignancy of the GIST(P<0.05);There was no statistical significance between the expression level of p53 and the malignancy of the GIST(P>0.05).Conclusions: Over expression of bcl-2 indicates the malignancy of GIST.Therefore,bcl-2 may act as a reference index in assessing the malignancy degree of GIST.The expression of p53 has no correlation with the formation,occurrence and development of GIST.Its expression is relatively low and nonspecific,and is of little value in judging the malignancy degree of GIST.
Objective: To investigate the relation between the expression of bcl-2 and p53 in gastrointestinal stromal tumors(GIST).Methods: The expression of bcl-2 and p53 was detected in 53 cases of GIST by immunohistochemical technique,and the data was analyzed statistically.Results: The expression of bcl-2 and p53 in GIST was not significantlt different between the male and the female(P>0.05);There was no statistical significance between diameter and karyomitosis of GIST in these cases(P>0.05);There was no statistical significance between the expression of p53 and the malignancy of the GIST(P>0.05);There was statistical significance between the expression rate of bcl-2 and the malignancy of the GIST(P<0.01);There was statistical significance between the expression level of bcl-2 and the malignancy of the GIST(P<0.05);There was no statistical significance between the expression level of p53 and the malignancy of the GIST(P>0.05).Conclusions: Over expression of bcl-2 indicates the malignancy of GIST.Therefore,bcl-2 may act as a reference index in assessing the malignancy degree of GIST.The expression of p53 has no correlation with the formation,occurrence and development of GIST.Its expression is relatively low and nonspecific,and is of little value in judging the malignancy degree of GIST.
2009, 34(7): 598-600.
Abstract:
Objective: To evaluate the application of thinprep cytologic test(TCT) combined colposcopy with biopsy in cervical carcinoma investigation.Methods: To applicate the methods which TCT combined colposcope with biopsy in cervical lesion diagnosis,and analysis the results by pathological diagnosis.Results: One hundred and sixty-four cases were detected as atypical squamous cell of undetermined significance(ASCUS),low-grade squamous intraepithelial lesion(LSIL),high-grade squamous intraepithelial lesion(HSIL) and benign changes with a bit cell hyperplasia in TCT,and these cases were biopsied under colposcope.Sixty-four cases were detected accompanied with inflammation,the positive rate was 39.0%;38 cases were detected with CIN1;19 cases were detected with CIN2;37 cases were detected with CIN3;6 cases were detected with the forepart of soakage carcinoma.Conclusions: The examination of TCT combined colposcope with pathological biopsy is as soon as possible in detecting the cervical procarcinoma and carcinoma.
Objective: To evaluate the application of thinprep cytologic test(TCT) combined colposcopy with biopsy in cervical carcinoma investigation.Methods: To applicate the methods which TCT combined colposcope with biopsy in cervical lesion diagnosis,and analysis the results by pathological diagnosis.Results: One hundred and sixty-four cases were detected as atypical squamous cell of undetermined significance(ASCUS),low-grade squamous intraepithelial lesion(LSIL),high-grade squamous intraepithelial lesion(HSIL) and benign changes with a bit cell hyperplasia in TCT,and these cases were biopsied under colposcope.Sixty-four cases were detected accompanied with inflammation,the positive rate was 39.0%;38 cases were detected with CIN1;19 cases were detected with CIN2;37 cases were detected with CIN3;6 cases were detected with the forepart of soakage carcinoma.Conclusions: The examination of TCT combined colposcope with pathological biopsy is as soon as possible in detecting the cervical procarcinoma and carcinoma.
2009, 34(7): 601-603.
Abstract:
Objective: To value the the efficacy and toxicities of gemcitabine(GEM) associated with navelbine(NVB) (GN protocol) on treatment of patients with advanced non-small cell lung cancer(NSCLC) resistant to platinum.Methods: Twenty-three cases of NSCLC anciently treated with platinum for two cycles with no obvious therapeutic effect were treated with GN.The details on the therapy are as follows:GEM was taken through the intravenous dripping at 1 000 mg/m2 on the day 1st and day 8th while NVB was taken through the intravenous dripping at 25 mg/m2 on the day 1st and day 8th.Results: These patients who were treated with GN were acquired 39.1% of the total effective rate,9.8 months of the median survival time,5.7 months of the illness advancing time and 45.8% of one-year survival rate.The major toxicity lies with the hematology,it is manifested by 78.3% of the decrease on the white cellⅠ~Ⅱ,13.0% of the decrease on the white cell Ⅲ~Ⅳ,43.5% of theⅠ~Ⅱ decrease on the platelet and 30.4% of anemia.The toxicity in the non-hematology includes vomiting,nausea and local phlebitis and so on.Conclusions: GN protocol with GEM associated with NVB has a superior therapeutic effect on advanced NSCLC resistant to Platinum with endurable side effects,which is worth popularizing and applying in the clinic.
Objective: To value the the efficacy and toxicities of gemcitabine(GEM) associated with navelbine(NVB) (GN protocol) on treatment of patients with advanced non-small cell lung cancer(NSCLC) resistant to platinum.Methods: Twenty-three cases of NSCLC anciently treated with platinum for two cycles with no obvious therapeutic effect were treated with GN.The details on the therapy are as follows:GEM was taken through the intravenous dripping at 1 000 mg/m2 on the day 1st and day 8th while NVB was taken through the intravenous dripping at 25 mg/m2 on the day 1st and day 8th.Results: These patients who were treated with GN were acquired 39.1% of the total effective rate,9.8 months of the median survival time,5.7 months of the illness advancing time and 45.8% of one-year survival rate.The major toxicity lies with the hematology,it is manifested by 78.3% of the decrease on the white cellⅠ~Ⅱ,13.0% of the decrease on the white cell Ⅲ~Ⅳ,43.5% of theⅠ~Ⅱ decrease on the platelet and 30.4% of anemia.The toxicity in the non-hematology includes vomiting,nausea and local phlebitis and so on.Conclusions: GN protocol with GEM associated with NVB has a superior therapeutic effect on advanced NSCLC resistant to Platinum with endurable side effects,which is worth popularizing and applying in the clinic.
2009, 34(7): 603-605.
Abstract:
Objective: To investigate the changes of bone mineral density(BMD) in female patients with type 2 diabetes mellitus(T2DM) and the possible clinical related factors involved.Methods: The BMD was measured with the dual-energy X-ray absorptiometry technique at the lumbar(L2-L4) and proximal femur of 127 female patients with T2DM and 78 non-diabetic controls.The patients and controls were divided into groups according to the age and diabetic duration.The correlation of BMD with the age,duration of menopause,body mass index(BMI),course,HbA1c and serum lipids was studied by multivariate stepwise regression analysis.Results: The T2DM patients in 55-59 years-old group had a higher BMD than the controls(P<0.05 or P<0.01);the patients in 60-69 and 70-79 year-old groups had a higher BMD at L2 than the controls(P<0.05 or P<0.01);and the patients in 70-79 year-old group had a higher BMD at L3 than the controls(P<0.05 or P<0.01).The BMD at Ward's triangle was lower than that at lumbar,neck and G.T in each group(P<0.01).The BMD had no significant difference in T2DM patients with a diabetic course of less than 5 years,between 6-10 years and more than 10 years(P>0.05).Stepwise regression analysis showed that BMD at lumbar was negatively correlated with the age(P<0.05 or P<0.01);BMD at neck,Ward's triangle and G.T.was negatively correlated with the duration of menopause(P<0.01),and positively correlated with BMI(P<0.01).Diabetic duration,HbA1c and serum lipids had no correlation with BMD in T2DM patients.Conclusions: BMD in postmenopausal T2DM patients is significantly higher than or similar to that in the controls.Aging and long duration of menopause are risk factors for decreased BMD in T2DM patients.BMI may be a protective factor for bone loss.
Objective: To investigate the changes of bone mineral density(BMD) in female patients with type 2 diabetes mellitus(T2DM) and the possible clinical related factors involved.Methods: The BMD was measured with the dual-energy X-ray absorptiometry technique at the lumbar(L2-L4) and proximal femur of 127 female patients with T2DM and 78 non-diabetic controls.The patients and controls were divided into groups according to the age and diabetic duration.The correlation of BMD with the age,duration of menopause,body mass index(BMI),course,HbA1c and serum lipids was studied by multivariate stepwise regression analysis.Results: The T2DM patients in 55-59 years-old group had a higher BMD than the controls(P<0.05 or P<0.01);the patients in 60-69 and 70-79 year-old groups had a higher BMD at L2 than the controls(P<0.05 or P<0.01);and the patients in 70-79 year-old group had a higher BMD at L3 than the controls(P<0.05 or P<0.01).The BMD at Ward's triangle was lower than that at lumbar,neck and G.T in each group(P<0.01).The BMD had no significant difference in T2DM patients with a diabetic course of less than 5 years,between 6-10 years and more than 10 years(P>0.05).Stepwise regression analysis showed that BMD at lumbar was negatively correlated with the age(P<0.05 or P<0.01);BMD at neck,Ward's triangle and G.T.was negatively correlated with the duration of menopause(P<0.01),and positively correlated with BMI(P<0.01).Diabetic duration,HbA1c and serum lipids had no correlation with BMD in T2DM patients.Conclusions: BMD in postmenopausal T2DM patients is significantly higher than or similar to that in the controls.Aging and long duration of menopause are risk factors for decreased BMD in T2DM patients.BMI may be a protective factor for bone loss.
2009, 34(7): 606-607.
Abstract:
Objective: To discuss an effective treatment method of protecting the function and appearance of the deep-burned hands.Methods: Ten patients(16 dorsa of hands) with deep second degree burn were treated by early escharectomy and skin grafting.Functional rehabilitation of the hand was conducted when the dressing was removed.Results: All the wounds healed.The follow-up showed that the appearance and function of the hands were satisfactory.Conclusions: Early operation and post-operative exercise may protect the function and the appearance of the hand with deep second degree burn.
Objective: To discuss an effective treatment method of protecting the function and appearance of the deep-burned hands.Methods: Ten patients(16 dorsa of hands) with deep second degree burn were treated by early escharectomy and skin grafting.Functional rehabilitation of the hand was conducted when the dressing was removed.Results: All the wounds healed.The follow-up showed that the appearance and function of the hands were satisfactory.Conclusions: Early operation and post-operative exercise may protect the function and the appearance of the hand with deep second degree burn.
2009, 34(7): 608-609.
Abstract:
Objective: To summarize the experience in prevention and treatment of bile duct injury during laparoscopic cholecysteclomy(LC).Methods: Retrospective analysis on the clinical data of 30 cases of LC was carried out.The different operation modes were selected according to the injury area and degree of bile duct and the discovered time.Results: Nine cases who treated urgently were recovered well during the operation period.In the 21 cases who were found with bile duct injury after the operation,two cases were died,and in which one was died with leakage of bile and celiac infection,and another was died with reiterative cholangitis and hepatic insufficiency.Other cases were recovered well.Conclusions: During LC,the operative rule should always be strictly complied and the key to preventing bile duct injury is to avoid clipping,cutting and coagulationblindly blindly.
Objective: To summarize the experience in prevention and treatment of bile duct injury during laparoscopic cholecysteclomy(LC).Methods: Retrospective analysis on the clinical data of 30 cases of LC was carried out.The different operation modes were selected according to the injury area and degree of bile duct and the discovered time.Results: Nine cases who treated urgently were recovered well during the operation period.In the 21 cases who were found with bile duct injury after the operation,two cases were died,and in which one was died with leakage of bile and celiac infection,and another was died with reiterative cholangitis and hepatic insufficiency.Other cases were recovered well.Conclusions: During LC,the operative rule should always be strictly complied and the key to preventing bile duct injury is to avoid clipping,cutting and coagulationblindly blindly.
2009, 34(7): 617-619.
Abstract:
Objective: To study the significance of treatment based on categorical identification of the traditional Chinese medicine(TCM) for facial paralysis efficacy with acupuncture treatment.Methods: Sixty-eight patients were divided into two groups through single-blind method randomly:the observation group(differentiation in the treatment,36 cases),and the control group(non-differentiation in the treatment,32 cases).The observation group were divided into three types according to syndrome symptoms:Feng Xie into the Internal Organs;the Internal Organs silted by phlegm and dampness;Qi and blood deficiency.According to the treatment based on categorical identification of the traditional Chinese medicine,the acupuncture points were given in different selections;the same acupuncture points were selected in the control group.Then the efficacy was assessed after the period of treatment.Results: Differentiation in the observation group,the period of treatment and effects were improved than in the control group(P<0.05).Conclusions: Treatment of facial paralysis with acupuncture therapy is of great significance,it can improve the effect and shorten the period of treatment.Categorical identification of the TCM has a significant clinical directive function.
Objective: To study the significance of treatment based on categorical identification of the traditional Chinese medicine(TCM) for facial paralysis efficacy with acupuncture treatment.Methods: Sixty-eight patients were divided into two groups through single-blind method randomly:the observation group(differentiation in the treatment,36 cases),and the control group(non-differentiation in the treatment,32 cases).The observation group were divided into three types according to syndrome symptoms:Feng Xie into the Internal Organs;the Internal Organs silted by phlegm and dampness;Qi and blood deficiency.According to the treatment based on categorical identification of the traditional Chinese medicine,the acupuncture points were given in different selections;the same acupuncture points were selected in the control group.Then the efficacy was assessed after the period of treatment.Results: Differentiation in the observation group,the period of treatment and effects were improved than in the control group(P<0.05).Conclusions: Treatment of facial paralysis with acupuncture therapy is of great significance,it can improve the effect and shorten the period of treatment.Categorical identification of the TCM has a significant clinical directive function.
2009, 34(7): 619-622.
Abstract:
Objective: To explore the role of color doppler ultrasound in comparing the effects before and after treatment of carotid atherosclerotic plaque with Chinese medicine.Methods: Color doppler ultrasound was performed in 58 cases of carotid atherosclerosis.The echo property,size,inner and media thickness of the plaque,the stenosis of the lumens and the extent of the narrow spectrum of color doppler flow parameter changes were observed before and after the application of Chinese medicine.Results: The plaque in the treatment group was deflated to varied degree,the diameter of the intracavity was expanded,and the inner and media thickness was reduced(P<0.01).Conclusions: Color doppler ultrasound can accurately monitor the size of the carotid atherosclerotic plaque and assess the stenosis degree of the blood vessels,which may provide basis for early diagnosis and treatment of cerebrovascular diseases,thus reducing the incidence of cerebral infarction.
Objective: To explore the role of color doppler ultrasound in comparing the effects before and after treatment of carotid atherosclerotic plaque with Chinese medicine.Methods: Color doppler ultrasound was performed in 58 cases of carotid atherosclerosis.The echo property,size,inner and media thickness of the plaque,the stenosis of the lumens and the extent of the narrow spectrum of color doppler flow parameter changes were observed before and after the application of Chinese medicine.Results: The plaque in the treatment group was deflated to varied degree,the diameter of the intracavity was expanded,and the inner and media thickness was reduced(P<0.01).Conclusions: Color doppler ultrasound can accurately monitor the size of the carotid atherosclerotic plaque and assess the stenosis degree of the blood vessels,which may provide basis for early diagnosis and treatment of cerebrovascular diseases,thus reducing the incidence of cerebral infarction.
2009, 34(7): 622-625.
Abstract:
Objective: To investigate the extraction technology of hydrophilic components from seaweed,and to analyze the physical properties of the components.Methods: The extraction technology was studied with alkali as catalyst.The major factors affecting the extraction technology of the hydrophlic components from Gelidium amansii were considered,and extraction conditions were optimized by using yield as evaluation index.Results: Six hydrophilic extracts were obtained from seaweed and they had distinct differences in the major properties such as swelling ratio,weight loss and freezing point.Conclusions: The over-all properties of the obtained hydrophilic components from Gelidium amansii were the best of the 6 hydrophilic extracts from seaweed.
Objective: To investigate the extraction technology of hydrophilic components from seaweed,and to analyze the physical properties of the components.Methods: The extraction technology was studied with alkali as catalyst.The major factors affecting the extraction technology of the hydrophlic components from Gelidium amansii were considered,and extraction conditions were optimized by using yield as evaluation index.Results: Six hydrophilic extracts were obtained from seaweed and they had distinct differences in the major properties such as swelling ratio,weight loss and freezing point.Conclusions: The over-all properties of the obtained hydrophilic components from Gelidium amansii were the best of the 6 hydrophilic extracts from seaweed.
2009, 34(7): 625-627.
Abstract:
Objective: To screen and optimize the extraction technique of Weiling granules.Methods: The extraction yield of total flavonoids and 80% alcohol extractive were been as the investigative indexes,the best extraction technique was evaluated by orthogonal experimental design.Results: The optimized extraction technique was that the decoction pieces were added with 9 times of water,extracting three times for 50 minutes every time.Conclusions: The optimum extraction was simple,reasonable and useful for further development.
Objective: To screen and optimize the extraction technique of Weiling granules.Methods: The extraction yield of total flavonoids and 80% alcohol extractive were been as the investigative indexes,the best extraction technique was evaluated by orthogonal experimental design.Results: The optimized extraction technique was that the decoction pieces were added with 9 times of water,extracting three times for 50 minutes every time.Conclusions: The optimum extraction was simple,reasonable and useful for further development.
2009, 34(7): 628-630.
Abstract:
Objective: To study the value of bedside high-frequence ultrasound in diagnosis of neonatal cerebral disease.Methods: Seventy eight cases of neonatal cerebral disease were examined bedside by ultrasound high frequency probe,and the result was compared with that by computer tomography(CT).Results: Intracranial hemorrhage was observed in 33 cases,hypoxic-ischemic encephalopathy in 41 cases,encephalodysplasia in 1 case and intracranial calcification in 3 cases by cerebral ultrasound;The result by ultrasonic examination for cerebral disease coincided with that by computer tomography except subarachnoid hemorrhage,and the changes of the cerebral disease could be monitored by ultrasound.Conclusions: Ultrasound is of high value in diagnosis of neonatal cerebral disease and has the advantages of no radiation injury,convenience,easy application and cost efficacy.
Objective: To study the value of bedside high-frequence ultrasound in diagnosis of neonatal cerebral disease.Methods: Seventy eight cases of neonatal cerebral disease were examined bedside by ultrasound high frequency probe,and the result was compared with that by computer tomography(CT).Results: Intracranial hemorrhage was observed in 33 cases,hypoxic-ischemic encephalopathy in 41 cases,encephalodysplasia in 1 case and intracranial calcification in 3 cases by cerebral ultrasound;The result by ultrasonic examination for cerebral disease coincided with that by computer tomography except subarachnoid hemorrhage,and the changes of the cerebral disease could be monitored by ultrasound.Conclusions: Ultrasound is of high value in diagnosis of neonatal cerebral disease and has the advantages of no radiation injury,convenience,easy application and cost efficacy.
2009, 34(7): 632-634.
Abstract:
Objective: To discuss the experimental evaluation and clinical significance of human leukoyte antigen(HLA) immunization therapy of habitual abortion on unknown causes.Methods: Thirty-six patients who had abortion over 3 times and their husbands were detected of the HLA by serum assay.Results: Twenty-nine of the 36 cases treated with lymphocyte therapy were successful in pregnancy,the success rate being 87.5%.Conclusions: Intradermic injection of the husband's lymphocyte is effective in treatment of habitual abortion of unknown causes and the therapy is simple and safe in operation.It is worth popularizing.
Objective: To discuss the experimental evaluation and clinical significance of human leukoyte antigen(HLA) immunization therapy of habitual abortion on unknown causes.Methods: Thirty-six patients who had abortion over 3 times and their husbands were detected of the HLA by serum assay.Results: Twenty-nine of the 36 cases treated with lymphocyte therapy were successful in pregnancy,the success rate being 87.5%.Conclusions: Intradermic injection of the husband's lymphocyte is effective in treatment of habitual abortion of unknown causes and the therapy is simple and safe in operation.It is worth popularizing.
2009, 34(7): 635-637.
Abstract:
Objective: To compare irregular antibodies' postive rates of the first and repeated blood transfusions,and to approach applied value of the crossmatching test by microcolumn gel test(MGT) and manual polybrene test(MPT) in the sustainable hemtodialysis' patients.Methods: Ninety-six patients sustainable hematodialysis' who required blood transfusion were crossmatched by MGT and MPT.Results: In 462 cross matching tests for 96 patients,the difference of crossmatching compatibility showed statistical significance between MGT and MPT(P<0.01).Among the total,62 cases of MGT major and minor incompatibility were positive by direct antiglobulin test.Moreover,with the increase of transfusion'times,the positive rate of irregular antibodies also increased by MGT and MPT(P<0.01).The total positive rate was higher using MGT than using MPT,the susceptibility of MGT was obviously higher than MPT(P<0.01).Conclusions: In sustainable hemtodialysis' patients,there will be line irregularity of antibodies after continual and repeated transfusions.In MGT,sensitized RBC will lead to difficulty of crossmatching test.In combination with MPT,we can further understand the nature of incompatibility,which can improve safety of transfusion.It might be of good complementarity when there is minor incompatibility of MGT in cross matching.
Objective: To compare irregular antibodies' postive rates of the first and repeated blood transfusions,and to approach applied value of the crossmatching test by microcolumn gel test(MGT) and manual polybrene test(MPT) in the sustainable hemtodialysis' patients.Methods: Ninety-six patients sustainable hematodialysis' who required blood transfusion were crossmatched by MGT and MPT.Results: In 462 cross matching tests for 96 patients,the difference of crossmatching compatibility showed statistical significance between MGT and MPT(P<0.01).Among the total,62 cases of MGT major and minor incompatibility were positive by direct antiglobulin test.Moreover,with the increase of transfusion'times,the positive rate of irregular antibodies also increased by MGT and MPT(P<0.01).The total positive rate was higher using MGT than using MPT,the susceptibility of MGT was obviously higher than MPT(P<0.01).Conclusions: In sustainable hemtodialysis' patients,there will be line irregularity of antibodies after continual and repeated transfusions.In MGT,sensitized RBC will lead to difficulty of crossmatching test.In combination with MPT,we can further understand the nature of incompatibility,which can improve safety of transfusion.It might be of good complementarity when there is minor incompatibility of MGT in cross matching.
2009, 34(7): 638-639.
Abstract:
Objective: To probe into the effect of body position intervention in relieving the discomfort of patients undergoing thyroid operation.Methods: Eighty patients undergoing thyroid surgery were randomly divided into two groups.Control group adopted routine thyroid operation posture,and the observed group received body position intervention such as preoperative body position training,body position altering and body position adjusting in the process of operation.Then the postural tolerance in the operative process,and the occurrence of headache and vomiting of the patients were observed.Results: The position tolerance in the observed group and control group was 17.5% and 42.5%,and the incidence of postoperative headache was 27.5% and 62.5%,respectively.The incidence of postoperative vomiting was 22.5% and 47.5%,respectively.The difference was significant between the two groups(P<0.05 to P<0.01).Conclusions: Postural intervention could improve the toleration,reduce the postoperative headache and vomiting,and prevent or relieve the postural discomfort of the patients undergoing thyroid surgery.
Objective: To probe into the effect of body position intervention in relieving the discomfort of patients undergoing thyroid operation.Methods: Eighty patients undergoing thyroid surgery were randomly divided into two groups.Control group adopted routine thyroid operation posture,and the observed group received body position intervention such as preoperative body position training,body position altering and body position adjusting in the process of operation.Then the postural tolerance in the operative process,and the occurrence of headache and vomiting of the patients were observed.Results: The position tolerance in the observed group and control group was 17.5% and 42.5%,and the incidence of postoperative headache was 27.5% and 62.5%,respectively.The incidence of postoperative vomiting was 22.5% and 47.5%,respectively.The difference was significant between the two groups(P<0.05 to P<0.01).Conclusions: Postural intervention could improve the toleration,reduce the postoperative headache and vomiting,and prevent or relieve the postural discomfort of the patients undergoing thyroid surgery.
2009, 34(7): 640-642.
Abstract:
Objective: To evaluate a new psychological nursing therapy happy factor stimulation in elevating the quality of life of the elderly patients who had retired from work.Methods: A total of 50 elderly patients with an age of over 80 in the gerontology department of our hospital were enrolled in the study.The happy factors we collected were their achievements in their early life.We stimulated their pride and joy by chatting with them about them.Their physiological and psychological reactions were observed before and after the therapy,and their quality of life was evaluated.Results: There was a significant difference in appraisal score before and after the happy factor-stimulation therapy(P<0.01).Conclusions: Happy factor stimulation therapy is simple and effective in elevating the life quality of the elderly patients who have retired from work
Objective: To evaluate a new psychological nursing therapy happy factor stimulation in elevating the quality of life of the elderly patients who had retired from work.Methods: A total of 50 elderly patients with an age of over 80 in the gerontology department of our hospital were enrolled in the study.The happy factors we collected were their achievements in their early life.We stimulated their pride and joy by chatting with them about them.Their physiological and psychological reactions were observed before and after the therapy,and their quality of life was evaluated.Results: There was a significant difference in appraisal score before and after the happy factor-stimulation therapy(P<0.01).Conclusions: Happy factor stimulation therapy is simple and effective in elevating the life quality of the elderly patients who have retired from work
2009, 34(7): 642-644.
Abstract:
Objective: To investigate the preventive effect of rehabilitation nursing care to foot drop in patients who suffering from deep burn of lower limbs.Methods: Sixty-two patients with deep burn of lower limbs were randomly divided into control group(n=36) and observation group(n=36).The patients in control group were taken routine nursing and in observation group were taken routine nursing with rehabilitation nursing care.Results: The motion range of ankle joint,dorsal flexion and plantar flexion in observation group were better than those in control group(P<0.01).There was no patient with foot drop in observation group while 16 patients with foot drop in control group.The difference of these two groups was significance(P<0.01).Conclusions: Rehabilitation nursing care could prevent foot drop in patients with deep burn of lower limbs.
Objective: To investigate the preventive effect of rehabilitation nursing care to foot drop in patients who suffering from deep burn of lower limbs.Methods: Sixty-two patients with deep burn of lower limbs were randomly divided into control group(n=36) and observation group(n=36).The patients in control group were taken routine nursing and in observation group were taken routine nursing with rehabilitation nursing care.Results: The motion range of ankle joint,dorsal flexion and plantar flexion in observation group were better than those in control group(P<0.01).There was no patient with foot drop in observation group while 16 patients with foot drop in control group.The difference of these two groups was significance(P<0.01).Conclusions: Rehabilitation nursing care could prevent foot drop in patients with deep burn of lower limbs.
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