• 中国科技论文统计源期刊
  • 中国科技核心期刊
  • 中国高校优秀期刊
  • 安徽省优秀科技期刊

2010 Vol. 35, No. 1

Display Method:
Establishment of suckling mouse model of extraintestinal rotavirus infection
XIA Qun, CHEN Lan-ju, CHEN Ming-wu, ZHOU Rui, SHEN Huai-yun, DING Zhou-zhi, XU Jia-li, XUE Lian, LIU Xin
2010, 35(1): 1-3.
Abstract:
Objective:To establish the suckling mouse model of extraintestinal rotavirus infection.Methods:Thirty-two ICR mouse aged from 10 to 11 days were randomly divided into two groups,with 16 in each.The extraintestinal infection group were inoculated by intraperitoneal injection of 150 μl simian rotavirus SAl1 (the virus titer of TCID50 was about 10-4) and the control group were inoculated by intraperitoneal injection of 150 μl normal saline.After inoculation,the mouse activities,diet,somatotype,change of hair color and stool were observed.All the suckling mouse were killed 4 days later,and the heart,liver,kidney,spleen and intestines were collected for pathological section and homogenate culture.Results:After two days of infection,the suckling mouse in extraintestinal infection group began to lose appetite,their clothing hair was tarnished and activities were decreased;They were dull,lethargy and slow to outside stimulus;meanwhile,their stool amount was reduced;the symptoms aggravated gradually and reached the peak at the fourth day;moreover,three mouse demonstrated the symptom of diarrhea.In the whole process of observation,the cumulative diarrhea rate and inception rate were 18.75% and 100.00%,respectively.Pathological changes were observed in the liver,kidney,spleen and intestines by light-microscope.After 72 hours of homogenate culture,cytopathic effect was observed in the liver,kidney and intestines,but no obvious changes were noticed in the heart or spleen.The suckling mouse in control group presented normal condition.Conclusions:It is feasible to establish the suckling mouse model of extraintestinal rotavirus infection with this method.
Effects of erythropoietin on the proliferation and differentiation of neural stem cells in hypoxia
ZHAO Bao-ming, ZHAO Li, GENG Hui-hui
2010, 35(1): 4-6,9.
Abstract:
Objective:To explore the influence of erythropoietin (EPO) on the proliferation and differentiation of neural stem cells (NSCs) in hypoxia.Methods:The NSCs were put into the incubator with of 10% O2,and EPO was added into the cultures during the proliferation and differentiation period of NSCs.The proliferation of NSCs was evaluated by MTT method and clone calculation.After the differentiation of NSCs with 10% fetal bovine serum (FBS),the differentiation ratio of NSCs into neurons and glia cells was detected by immunocytochemistry for neuron-specific enolase (NSE) and glia fibrillary acidic protein (GFAP).Results:The cells cultured were nestin positive;after differentiation,part of them were NSE positive and others were GFAP positive.The cloning efficiency of NSCs in normoxia and hypoxia group was (32.26±3.26)% and (48.93±4.34)% respectively.The cloning efficiency in the condition of EPO with hypoxia increased by 17.26% compared with that of the hypoxia group,and NSE positive cells increased significantly during differentiation.Conclusions:The proliferation of NSCs is promoted in the condition of hypoxia and differentiated into neurons;hypoxia can increase the proliferation of EPO and induce them to differentiation of more neurons.
Typing of calcarine sulcus on lateral median sagittal planes and its significance
ZHANG Yan, WANG Zhen-huan, SHEN Long-shan, ZHANG Jun-xiang, LIU Zhi-jun
2010, 35(1): 7-9.
Abstract:
Objective:To identify the morphous feature of calcarine sulcus (CS) on sagittal MRI planes and to provide reference for identifying CS on transverse MRI planes.Methods:The data of 30 healthy adult sagittal-sectional MRI was imported into efilm workstation in the form of Dicom 3.0.Typical morphous,continuous tracing and 3D-Cursor were employed for the identification,and the posterior segments of CS on median planes of 60 corpse brains were classified for comparison.Results:The morphous and localization of the CS were stable;the CS on lateral median saggital planes could be classified as comma,unimodal,double-hump and three-hump.Conclusions:The CS can be identified accurately by typical morphous,continuous tracing and 3D-Cursor,which will help to identify CS on transverse MRI planes.
Construction and identification of recombinant adenovirus with NT-3 gene
FAN Chi, GAO Xia, XU Lin, ZHU Guang-jie, CHEN Jie, MA Xiao-feng, DING Xiao-qiong, LU Ling, ZHOU Han
2010, 35(1): 10-13.
Abstract:
Objective:To construct the recombinant adenovirus vector carrying neurotrophin-3 (NT-3) gene.Methods:NT-3 and DsRed2 (including the ligation region pIRES2) fragment which had been digested by proper enzyme from NT-3-pIRES2-DsRed2 plasmid were cloned into adenovirus pAdShuttle-CMV plasmid.Adenovirus vector pAdShuttle-CMV-NT-3-DsRed2 were electroporated into BJ5183 which had been transformed into pAdEasy-1 previously to have the recombination with pAdEasy-1.Recombinant AdEasy plasmid DNA was analyzed and linearized by PacⅠ,then transfected into 293A cells with liposome method.The adenovirus that expressed NT-3 ptotein and red fluorescence was successfully constructed.The adenovirus was amplified in 293A cells three times,and high quality adenovirus was obtained by cesium chloride density gradient centrifugation.Western blot confirmed the expresseion of the NT-3 protein in 293T cells.Results:With the system of Adshuttle,a recombinant adenovirus expressing NT-3 protein and red fluorescence was successfully constructed.Conclusions:The recombinant adenovirus carrying NT-3 gene can be constructed with the system of Adeasy.
2010, 35(1): 14-16.
Abstract:
Expression and clinical significance of lung resistance related protein and multidrug resistance in lung cancer
HU Jun-feng, XIA Xue-mei, LI Dian-ming, Chen Ze-nong, FENG Zhen-zhong, CHEN Yu-qing
2010, 35(1): 17-19.
Abstract:
Objective:To investigate the expression and clinical significance of lung resistance related protein (LRP) and multidrug resistance associated protein (MRP) in lung cancer.Methods:Sixty two cases of lung cancer were detected of the presence of LRP and MRP by immunohistochemical analysis.Results:The expression of LRP and MRP,in lung cancer was 61.3% and 70.0% respectively,and their common positive expression was 51.6%.The expreesion of LRP and MRP had no significant diffrerence in the clinicopathological variables including age,sex,pathology type,differentiation degree or TNM stage (P>0.05).In addition,LRP had no correlation with MRP (P>0.05).Conclusions:The expression of LRP and MRP is related with lung cancer's intrinsic drug resistance,but not obviously coorelated with the clinicopathological characteristics.There is no correlation between LRP and MRP.
Rhomboid flap for repair of skin defects in face
ZHOU Ping-hui, ZHANG Li, GE Shu-xing, LI Xu-wen, WANG Huai-gu
2010, 35(1): 20-22.
Abstract:
Objective:To evaluate the effect of repairing the facial skin defect with the rhomboid flap.Methods:Thirty cases of small facial skin defects were repaired using rhomboid flaps;the facial skin defects ranged from 0.5 cm×0.6 cm to 3.0 cm×3.0 cm,and the donor site was directly sutured.Results:All the flaps survived with primary healing,and the cosmetic results were satisfactory.Conclusions:The rhomboid flap can be used for the coverage of small facial skin defects with satisfactory results.It is worth popularizing.
Methylation of p16 gene promoter in patients with breast cancer tissue
ZHENG Rong-sheng, ZHANG Zhe
2010, 35(1): 22-24.
Abstract:
Objective:To investigate the methylation of p16 gene promoter in patients with breast cancer tissue.Methods:The methylation status of p16 gene promoter in tumor tissue samples was detected through methylation-specific polymeras chain reaction (MS-PCR).Results:The positive rate of p16 gene promoter methylation was 30.5% in tumor tissue.The aberrant methylation of p16 gene promoter in tumor tissues had no correlation to patient's tumor staging,tumor size,histological type,menstruation status,lymphonode metastasis,hormone receptor and family history (P>0.05).Conclusions:p16 gene promoter methylation takes part in the breast cancer's carcinogenesis and this is an earlier event.Methylation of p16 gene promoter is probably used as molecular biology marker in early diagnosis and screen of breast cancer.
Analysis of complications in young children with cleft lip and palate during the waking period of anesthesia after surgery operation
ZHANG Song, ZHANG Zhi-wu, XU Jing, GAO Song, HUANG He, LI Guang-zao
2010, 35(1): 25-27.
Abstract:
Objective:To analyze the complications in children with cleft lip and palate during the waking period of anesthesia after surgery operation,and to find out the preventive and treatment measures.Methods:Six hundred and fifty children with cleft lip and palate were divided into three age groups:infant group (3 month-1 year),young child group (>1-3 year) and child group (>3-6 year).The complications in the waking period of anesthesia after surgery operation were observed and analyzed retrospectively.Results:The incidence of complications in each group was different.Hypoxemia was most often noted in infant group (23.0%),pyknocardia (7.4%) and hypoxemia (8.5%) were commonly observed in young child group,and vomiting (10.9%) and restlessness (6.5%) in child group (P<0.05).Conclusions:Children with cleft lip and palate should be closely monitored in the waking period of anesthesia group after surgery operation so that specific therapy and nursing can be applied in accordance to the age.
Feasibility of two-man performance switching to one-man performance in colonoscopy
WANG Jian-chao, YAO Ai-qun, WANG Qi-zhi, YAN Shan-jun
2010, 35(1): 27-28.
Abstract:
Objective:To investigate the feasibility of two-men colonoscopy performance switching of colonoscopic technique to one-man performance,and to assess its advantages.Methods:All the patients undergoing one-man colonoscopy performance in our hospital were enrolled in this study.The success rate,cercal intubation rate,time required for cercal intubation and incidence of complications were observed.Results:The success rate of one-man colonoscopy performance was 96.3%,and the mean time for examination was between 5 to 10 min.None of the patients experienced lesion residue,asenterobrosis or enterorrhagia.Conclusions:Our study suggests that one-man colonoscopy performance is simple and safe,causing less discomfort or pain for patients.This operation is clinically promising and worth popularizing.
Study on characteristics of anatomy and pathology of congenital cervical atresia
XIE Zhi-hong, LIU Jian-dong, ZHANG Xiao-ping, XIAO Hong, ZHANG Ning-zhi, LIU Yong-ying, MEI Li, ZHOU Ya-bo
2010, 35(1): 29-32.
Abstract:
Objective:To study the characteristics of anatomy and pathology of congenital cervical atresia and investigate the appropriateness of cervicovaginal plasty.Methods:The pathological examination was performed on hysterectomy specimens from 1 case of type Ⅰ,4 cases of type Ⅱ,2 cases of type Ⅲ and 1 case of type Ⅳ,and on biopsy tissue specimens of hematocele cyst cavity that connected under uterine body from 5 cases of type Ⅰ.The prognosis of patients with uterus preserved was followed up.Results:After 18 cases of patients with Type Ⅰ cervix atresia who were performed with cervicovaginal plasty,none of case was suffered from dysmenorrhea within half a year.Long-term follow-up on 13 cases of patients complicated with complete vaginal atresia,3 case-times of 2 persons have been performed lower uterine segmental cesarean section under natural pregnancy till full term,resulting 2 male babies and 1 female baby had been born successfully.One case of type Ⅱ patient who was performed with cervicovaginal plasty with combination of abdomen and cervix still suffered from dysmenorrheal and was no pregnancy.Two cases of type Ⅳ patient were performed cervicovaginal plasty with combine of abdomen and cervix with catheters indwelling in cervix duct cavities when surgery,dysmenorrhea was not happened.Conclusions:The diagnostic criterion for categorization of congenital cervical atresia is of significant clinical value for its diagnosis and treatment.
Evaluation of health-related quality of life in patients having received reconstruction of anterior cruciate ligament
WANG Wei, WANG Zhi-qiang, YUAN Xiu-hua
2010, 35(1): 32-34.
Abstract:
Objective:To evaluate the limitation of Lysholm score in assessing the life quality of patients having undergone reconstruction of anterior cruciate ligament (ACL).Methods:Forty-nine patients (50 knees) who had received reconstruction of ACL were followed up for 6 to 12 months,and their quality of life was investigated by Lysholm and MOS 36-item short-form health survey (SF-36) before and six months after the operation.The relativity between the scores by Lysholm and by SF-36 were analyzed.Results:The scores by both Lysholm and SF-36 were significantly improved 6 months after the operation compared with those before the operation (P<0.01),but the scores of each item by SF-36 were different.Conclusions:It suggests that Lysholm score can assess the physical function and pain relief in the patients who had received reconstruction of ACL,but has limitation in evaluating the quality of life and other improvements.So it is of great significance to combine Lysholm with SF-36 in evaluating the results of reconstruction of ACL.
Clinical study on insulin analogue aspart 30 in the treatment of type 2 diabetes mellitus
SUN Wei, ZHU Jiang, XU Mian
2010, 35(1): 35-36.
Abstract:
Objective:To observe the clinical therapeutic effects,safety and resistance of insulin analogue aspart 30 in treatment for type 2 diabetes mellitus.Methods:Forty patients with type 2 diabetes mellitus.were randomly divided into A group and B group,aspart 30 was used in A group patients while novolin 30R was used in B group patients,A group and B group patients were treated twice daily in morning and evening respectively.And the drug doses were adjusted momentarily according to the concentration of blood glucose in these patients.These parameters including the concentration of fasting plasma glucose (FPG),concentration of 2 hours postprandial glucose (2hPG),therapeutic time,insulin dose and the level of hypoglycemia were compared between these two groups.Results:Aspart 30 and novolin 30R could decrease the concentration of blood glucose efficiently (P<0.01),and there were no significant differences in these two groups (P>0.05).The level of hypoglycemia in aspart 30 group was higher than in novolin 30R group (P<0.05),especially the level of severe hypoglycemia at night.Conclusions:Aspart 30 is an effective and high safety drug in treatment for type 2 diabetes mellitus.The resistance and compliance of aspart 30 is better than novolin 30R.
The significance of expressions of vascular endothelial growth factor and estrogen receptor in papillary thyroid carcinomas and thyroid adenomas
WENG Sheng-bin, ZHANG Jian-bo, ZHANG Shu-yan, ZHENG Chao, BAI Jie, XU De-long
2010, 35(1): 37-39.
Abstract:
Objective:To investigate the significance of vascular endothelial growth factor (VEGF) and estrogen receptor (ER) expressions in papillary thyroid carcinoma,thyroid follicular adenoma and adjacent normal tissues,further to study the clinical significance of these two markers in treatment strategies of thyroid carcinoma and estimating prognosis.Methods:Thirty papillary thyroid carcinomas tissues,30 thyroid follicular adenomas tissues and 30 adjacent normal tissues were collected.Immunohistochemical S-P method was used to detect the expressions of VEGF and ER.Results:The expressions of VEGF and ER in papillary thyroid carcinoma and thyroid follicular adenoma both had significant differences,and both of them were higher than that in adjacent normal tissues (P<0.05).The positive rate of VEGF and ER expressions in papillary thyroid carcinoma had the negative correlation (P<0.05).Conclusions:The expressions of VEGF and ER could be as diagnostic indexes for papillary thyroid carcinoma.They also could be as the important indexes for evaluating the biological characteristics of papillary thyroid carcinoma and thyroid follicular adenoma and had the significant guiding role for clinical treatment and prognostic analysis.
Correlation analysis of TIMI blood flow,vascular endothelial function and influential factors
LU Wei-hong, WANG Ru-xing, YANG Zhen-yu, CAO Yun-xiang
2010, 35(1): 40-42.
Abstract:
Objective:To analyze the correlation between the coronary artery TIMI blood flow and vascular endothelial function,concentrations of serum homocysteine and cholesterin as well as.Methods:One hundred and twenty patients received coronary angiography were selected.The main data (baseline of brachial artery,the flow-mediated dilatation and the nitroglycerin-induced dilatation) of the endothelial function were measured with high resolution ultrasonography before coronary angiography was performed and the concentrations of serum homocysteine and cholesterin were detected.Then the patients were grouped by TIMI blood flow as TIMI 3,2,1,0.Results:The vascular endothelial function,the concentration of serum homocysteine and cholesterin were significant different among the TIMI grade groups (P<0.01).Conclusions:TIMI blood flow is correlated with the vascular endothelial function as well the concentration of serum homocysteine and cholesterin.The lower the grade of TIMI blood flow is,the heavier the vascular endothelial dilatation function damage will be,and the higher the concentrations of serum homocysteine and cholesterin.
Mineral trioxide aggregate as direct pulp capping agent in human teeth
XU Ji-qun
2010, 35(1): 42-43.
Abstract:
Objective:To observe the effect of mineral trioxide aggregate (MTA) as direct pulp capping agent in human teeth.Methods:Fifty teeth in patients between 18 and 40 years of age were randomly divided into two groups.The exposed pulps were capped with MTA or calcium hydroxide,respectively.All the cases were followed up for 2 and 3 years.Results:The pulp vitality and dentinal bridge thickness were both higher and thicker in the MTA group than in the calcium hydroxide group,but there was no significant statistical difference in the success rate between the two groups (P>0.05).Conclusions:MTA may be an ideal material as direct pulp capping agent in human teeth.
Analysis of the factors influencing the sleep of patients in ICU
Dong Xiu-yun
2010, 35(1): 44-45.
Abstract:
Objective:To investigate and analyze the sleeping condition of patient in ICU department.Methods:One hundred twenty-four patients in ICU department were investigated with SRSS and self-designed questionnaire.Results:The SRSS score of 80.6% patients was less than 23,and they felt their sleep quality bad.The influencing factors included worrying about their disease and prognosis,scant visit,lack of company,psychological burden and noises.Conclusions:The patients in ICU department have certain sleep problems and the nursing staff should take measures to improve their sleep quality.
Montelukast for treatment of bronchiolitis:a report of 25 cases
GAO Da-ming, MA Jia-ming
2010, 35(1): 46-47.
Abstract:
Objective:To observe the curative effect of montelukast on patients with bronchiolitis.Methods:Fourty-nine cases of young children with bronchiolitis were randomly divided in two groups.The treatment group (n=25) received montelukast in addition to conventional therapy,and the control group (n=24) received routine therapy only.The effects were evaluated and compared.Results:The curative effect of the treatment group was superior to that of the control group (P<0.05),and the sign and symptom relieving duration of the patients in the treatment group was significantly shorter than that of the control group (P<0.05).Conclusions:Oral administration of montelukast is effective,secure and convenient for treatment of patients with bronchiolitis.
Repairing complex anterior urethral stricture with adjacent pedicle complex tissue flaps:report of 12 cases
HOU Jin-hua, GU Heng, WANG Chang-bing, YU Tong-hui
2010, 35(1): 48-49.
Abstract:
Objective:To observe the effects of two kinds of adjacent pedicle complex tissue flaps on the repair of serious long anterior urethral stricture.Methods:Preputial pedicle tissue flaps and vascularized scrotal septum pedicle flaps were applied to repairing serious long anterior urethral stricture,and the effects were evaluated.Results:The operation was successful in all the 12 cases.Ten cases healed at one stage with smooth urination and no need for urethral dilation.No urethral restenosis occurred during the follow-up of 2-5 years.Urethral fistula occurred in 1 case,which was healed by second repairing.Hypospadias between navicular fossa and urethra external orifice was formed in 1 case,which had no influence on urination.Conclusions:Adjacent pedicle complex tissue flaps have many advantages for repair of serious long anterior urethral stricture:the material is easy to obtain,the flap has a good blood circulation and the wound healed well,leaving less chance of forming restenosis.It is one of the choice methods for the repair of long urethral stricture.
Analysis of 105 cases of traumatic subdural hygroma
LU Dian-pei
2010, 35(1): 50-51.
Abstract:
Objective:To study the clinical features,pathogenesis and treatment of traumatic subdural hygroma.Methods:The clinical data of 105 cases of traumatic subdural hygroma were retrospectively analyzed.Results:Of the 105 cases,64 were treated by non-surgery therapy and 41 by surgical intervention.In the non-surgery group,the result was good in 8 cases,fair in 31 cases and poor in 10 cases;and the effective rate was 79.6%.In the surgical intervention group,the result was good in 15 cases,fair in 20 cases and poor in 6 cases;and the response rate was 85.4%.The total effective rate was 82.2%.Conclusions:Combined therapy should be adopted in treatment of patients with traumatic subdural hygroma.
Expression and clinical significance of Ki-67,E-Cad and nm23 in human invasive pituitary adenomas
LUO Zhi-mou, YUAN Chun-yan, XIE Yun, PAN Yu-lin, PU Wen-lan, CAI Pei-ran
2010, 35(1): 52-54.
Abstract:
Objective:To study the association of the expression of Ki-67,E-Cad and nm23 with the volume,hormone secretion and invasion of pituitary adenomas.Methods:The expression of Ki-67,E-Cad and nm23 in 52 cases of pituitary adenomas was examined by immunohistochemical methods.Results:The expression level of Ki-67 in the invasive and nonsecretive pituitary adenomas was significantly higher than that in the noninvasive and secretive ones,and the expression level of Ki-67 was not related to the volumes of pituitary adenomas (P>0.05).The expression level of E-Cad in the invasive and unsecretive pituitary adenomas was significantly lower than that in the noninvasive and secretive ones (P<0.05),and the expression level of E-Cad was negatively correlated with the volumes of pituitary adenomas (P>0.05).The expression level of nm23 in the invasive pituitary adenomas was significantly lower than that in the noninvasive ones (P<0.05),and was not related to the hormone typing and volume of the tumor (P>0.05).Conclusions:High expression of Ki-67 and low expression of E-cad and nm23 are positively related to the invasiveness of pituitary adenomas,and may affect the cell differentiation and promote proliferation of the cells in pituitary adenomas.Thus,the expression of Ki-67,E-Cad and nm23 could be used to evaluate the invasion and prognosis of pituitary adenoma.
The clinical efficacy of adefovir on chronic hepatitis B
SHANG Li-li
2010, 35(1): 54-55.
Abstract:
Objective:To observe antiviral efficacy of adefovir on chronic hepatitis B.Methods:Thirty-four cases of patients with chronic hepatitis B were administered oral dose of 10 mg of adefovir once daily.HBVDNA,hepatic function and the serum HBV markers were detected every three months.Results:After 12 months' treatment,HBVDNA converted to negative in 17 cases (50%).Among them,the HBVDNA negative conversion rate in patients whose HBVDNA was less than 107 cop/ml was 66.6%,and it was 23% in patients whose HBVDNA was ≥ 107 cop/ml.There was significant difference between these two kinds of patients (P<0.05).The HBVDNA negative conversion rate in patients whose ALT was less than two folds of normal value was 20%,and it was 71.4% in patients whose ALT was more than two folds of normal value.There was also significant difference between these two kinds of patients (P<0.05).There no correlation between HBVDNA negatives conversion rate and the mode of hepatitis B serum markers (P>0.05).Conclusions:Adefovir is effective in HBVDNA negative conversion rate for the patients with low HBV load and high ALT levels.
2010, 35(1): 56-57.
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2010, 35(1): 57-58.
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2010, 35(1): 58-59.
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2010, 35(1): 59-60.
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2010, 35(1): 61-62.
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2010, 35(1): 62-63.
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Pathologic factors and CT manifestation of taumatic cerebral lacunar infarction
ZHANG Shu-bao, YIAN Guang-lin, ZHANG Bo, HE Xiao-ping
2010, 35(1): 64-65.
Abstract:
Objective:To analyze the relationship between the pathologic factors of traumatic cerebral lacunar infarction (TCLI) and the occurrence of the disease.Methods:Spiral CT scan and brain scan were performed in 39 cases of TCLI,and the clinical manifestation and CT findings were analyzed.Results:All the TCLI occurred in the region of internal capsule,appearing as small sheet or small round shadow with unclear margin.The lesion was located in double hemisphere in 11 cases and in unilateral hemisphere in 28 cases.Twenty-nine cases were accompanied by lenticular nucleus calcification in speckle,dot and sand-like high density shadow.Conclusions:The calcification in the basal ganglia is the main pathologic basis of TCLI.The injured uneven swollen cerebral tissue can cause displacement of calcification in the basal ganglia and press the vessel,which result in infarction of blood-supply cerebral tissue,and is the main pathologic factor for basal ganglia TCLI.
2010, 35(1): 65-67.
Abstract:
Clinical efficacy of Bushen Huayu Lishui decotion on diabetic nephropathy:Report of 56 cases
WANG Jian-sheng
2010, 35(1): 67-69.
Abstract:
Objective:To observe the effect of Bushen Huayu Lishui decoction in treatment of diabetic nephropathy.Methods:Fifty-six subjects were randomized into two groups.The control group were administered routine therapy to control the blood sugar,while the treatment group received Bushen Huayu Lishui decoction in addition to the routine therapy.The results between the two groups were compared and analyzed one month after treatment.Results:The effect was obviously better in the treatment group than in the control group.The difference was significant (P<0.01).The fasting plasma glucose,the fixed quantity of 24 h urine protein and plasma lipoprotein improved obviously (P<0.01).Conclusions:Bushen Huayu Lishui decoction can greatly improve the renal function of patients with diabetic nephropathy.
2010, 35(1): 69-70.
Abstract:
The employment training pattern of college graduates
XUAN Yang, SHI Yong-qing, LI Zhi-gang, ZHANG Lian-qiang, WANG Yu
2010, 35(1): 71-73.
Abstract:
Objective:To design the employment training pattern of college graduates,promoting comprehensive qualities and employment capability of college students.Methods:Systematic employment training modules and contents were designed scientifically;study objectives were trained on employment intensively for short time in various forms;after the training a simulative job fair was held;an experimental group and a control group were set for blind assessment;training effect was checked and assessed.Results:The comprehensive score of the experimental group was 87.6±3.09,and that of the control group was 63.5±7.20.The difference was statistical significance (P<0.01).Conclusions:The designed employment training pattern after graduation is practical with obvious effects and realistic significance,which can provide practical,systematic and standard training scheme for colleges in graduate employment and can also be the reference for relevant colleges in graduates training and guidance.
Exploration in teaching Enterobius vermicularis eggs in human parasitology
CHEN Xing-zhi, HU Shou-feng, XIA Hui, YANG Xiao-di
2010, 35(1): 74-76.
Abstract:
Objective:To improve the teaching of Enterobius vermicularis eggs,a portion of teaching contents in human parasitology.Methods:The class was carried out by systematically analyzing the plane and spatial shape of Enterobius vermicularis eggs,structure of eggshell,with or without egg lid,and so on.Results:Satisfactory effects were obtained and the students mastered the morphosis of Enterobius vermicularis well.Conclusions:Presenting the scientific research achievements about Enterobius vermicularis eggs to the students by multimedia in the teaching process can develop the students thinking ability and improve the teaching effect.
Exploration of teaching reformation in experimental course of the preventive medicine
ZHAO Hong, ZHOU Chun-xian, JIANG Cheng-mei, SHEN Ling, WANG Jian-jun, WANG Chun-hua, ZHANG Jie, ZHANG Yu-yuan, YAO Rong-ying, ZHOU Zhan-wei
2010, 35(1): 76-78.
Abstract:
Objective:To improve the teaching quality in experiment of preventive medicine by reformation in teaching model.Methods:The traditional teaching model of preventive medicine was reformed and the course "Experimental Course of Preventive Medicine" was set up.A serious of measures to reforms were performed in the experimental teaching materials,teaching content,teaching methods,experimental evaluation model and to strengthen laboratory management and so on.Results:Students' innovation and research abilities were improved by experiment teaching reform of preventive medicine.Conclusions:Experimental integration are beneficial to practice and innovation in preventive medicine personnel training.
The primary application of PBL teaching method in histology and embryology course
LI Hui-hui, GUAN Su-dong, ZHUO Yu-ya
2010, 35(1): 79-80.
Abstract:
Objective:To explore the application effects of problem based learning (PBL) teaching method in histology and embryology course.Methods:The PBL teaching method was applied in histology and embryology course to enable students to learn knowledge through questions,and form the knowledge chain with related contents.Results:The PBL teaching method increased the students' learning effect,cultured the students' self-learning ability,analysis ability and oral expression ability.The teachers' qualities were also improved.Conclusions:Using PBL teaching method appropriately in histology and embryology course can activate learning contents,cultivate and develop students' creative thinking skill and stimulate students' learning interest.The PBL teaching is worthy of further researching and extending.
Analysis of related factors influencing the self-concept of adolescencents in non-public schools
ZHONG Hui, LI Xiao-si, LI Ze-ai, DONG Yi, WANG Ke-ming, MA Shu-hui, TAO Ling-zhi
2010, 35(1): 81-83.
Abstract:
Objective:To study the characteristics of self-concept of adolescencents in non-public schools and the related factors.Methods:Seven hundred and fifty-two students in a non-public school in Hefei city were included in the study.All the students were interviewed with the Piers-Harris children's self-concept scale (PHCSS) and self-made questionnaires.The data were analyzed with SPSS 13.0 statistical package.Results:The scores of behavior,intelligence,anxiety,gregarious,happiness and the total scales had significant differences between the adolescencents in non-public schools and norm children (P<0.01).The self-concept scores were related with study pressure,relationship with parents,economic level,parenting style,the school life,and so on.Conclusions:The self-concept of adolescencents in non-public schools is related to factors such as families,schools and so on.
Effect of temperature intervention nursing to senile patients during the recovery period after general anesthesia
HONG Li-xia, MIN Li-xia
2010, 35(1): 83-84.
Abstract:
Objective:To investigate the incubation nursing to senile patients during the recovery period after general anesthesia.Methods:Eighty senile patients were randomly divided into control-group and survey-group,40 cases of each group.Patients in control-group were routinely cared,meanwhile,temperature intervention nursing were practiced to patients in survey-group by applying incubation tapetum,inputting warming liquid,humidificating DAR air-duct warmly etc.The prenarcotic temperature,initial temperature into post-anesthesia care unit (PACU),rewarming and detention time in PACU were monitored and the complications such as revival time delayed,dysarteriotony,shakes,restlessness were also monitored.Results:There were no statistical significance of prenarcotic temperature and initial temperature into PACU of two groups (P>0.05).However,there were remarkably statistical significance of the difference of rewarming time,detention time and kinds of complications (P<0.01).Conclusions:Intensifying temperature intervention nursing on senile patients during anesthesia recovery period can shorten detention time in PACU and reduce the correlated complications from hypothermia.
Radio frequency therapy with self-curing knife for benign uterus disease and perioperative nursing
YAN Hua, LI Zhi-min
2010, 35(1): 85-86.
Abstract:
Objective:To investigate the clinical value of radio frequency therapy with self-curing knife for benign uterus disease and nursing of the patients during operation.Methods:Radio frequency therapy under ultrasonic guidance was performed in 60 cases of uterus myoma with diameter of less than 5 cm and 8 cases of dysfunctional uterine bleeding.Pelvic pain and vaginal bleeding were recorded after the operation,and all the cases were followed up regularly.Results:Among the 60 cases of uterus myoma,57 cases were cured and 2 improved with a cure rate of 91.8% and an effective rate of 97.2%.Seven of the 8 cases of dysfunctional uterine bleeding were cured with a cure rate of 87.5% and an effective rate of 100%.Conclusions:Radio frequency therapy with self-curing knife is a new minimally invasive surgical procedure for treatment of benign uterus disease with affirmed results.
Effect of psychological intervention on recovery of cognitive function in patients with cerebral infarction
JIANG Hai-hua, SHI Heng-ping, XU Yan
2010, 35(1): 87-89.
Abstract:
Objective:To observe the effect of psychological intervention on recovery of cognitive function in patients with cerebral infarction.Methods:One hundred and eight patients with cerebral infarction were randomly divided into normal control group and psychological intervention group.Normal control group was given treatment and care according to "cerebral infarction clinical path".Psychological intervention group was given three times three-dimensional psychological interviews and psychological intervention according to different types of psychological disorders of cerebral infarction.Three times modified Barthel Index (BI) tests and Raven intelligence (RW) tests were taken before treatment,1 week and 2 weeks after treatment.Results:The BI total score in normal control group and psychological intervention group was higher 1 week and 2 weeks after treatment than before treatment (P<0.05 and P<0.01).The BI points of patients in normal control group were higher 1 week after treatment than before treatment (P<0.05-P<0.01),excepting for those with psychiatric and mood disorders (P>0.05).The BI total score in psychological intervention group increased significantly after 1 to 2 weeks treatment (P<0.01).The rehabilitation of intelligence had no significant difference between normal control group and psychological intervention group 1 week after treatment (P>0.05).After 2 weeks of treatment,the patients' intelligence in both groups improved significantly (P<0.01),but there was no statistically significant difference between the two groups (P>0.05).Conclusions:Psychological intervention can effectively improve the patients' living ability and facilitate or speed up the recovery of intelligence in patients with cerebral infarction.
2010, 35(1): 90-91.
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2010, 35(1): 91-92.
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2010, 35(1): 93-94.
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2010, 35(1): 94-96.
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2010, 35(1): 96-98.
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2010, 35(1): 98-99.
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2010, 35(1): 100-101.
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2010, 35(1): 102-103.
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2010, 35(1): 103-106.
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2010, 35(1): 106-108.
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