• 中国科技论文统计源期刊
  • 中国科技核心期刊
  • 中国高校优秀期刊
  • 安徽省优秀科技期刊

2010 Vol. 35, No. 2

Display Method:
Three dimensional visualization of cerebral postcentral sulcus
ZHANG Lei, WANG Zhen-huan, ZHANG Yan
2010, 35(2): 109-111,114.
Abstract:
Objective:To reconstruct three-dimentional model of cerebral postcentral sulcus for stereotactic surgery,interventional radiology and microsurgery.Methods:The thin traverse sections of MRI data of a normal adult head was imported to 3D-Doctor workstation on a personal computer,and the postcentral sulcus,the central sulcus,the lateral ventricle,the cerebral longitudinal fissure and the cerebrum were segmented and labeled with different colors.The three-dimensional model of them was constructed in 3D-Doctor workstation with the method of surface reconstruction.Results:The three-dimentional model of the postcentral sulcus in the whole brain enabled observation of the postcentral sulcus in three-dimensional virtual space and at random angles.Conclusions:The postcentral sulcus and its related adjoining structures can be observed from the three-dimentional model,which may provide assist for interventional radiology,stereotactic surgery and neurosurgery teaching.
Effects of activity and expression of sarcoplasmic reticulum Ca2+-ATPase in rat heart in infrarenal abdominal aorta occlusion induced ischemia and reperfusion injury
YU Ying, HU Jie, GAO Qin, WANG Si-ying
2010, 35(2): 112-114.
Abstract:
Objective:To investigate the sarcoplasmic reticulum Ca2+-ATPase(SERCA) activity and mRNA expression in rat heart in infrarenal abdominal aorta occlusion induced ischemia and reperfusion injury(I/R).Methods:Forty male Sprague-Dawley rats were randomized into five groups:pseudo-operation group,I/R2h group,I/R12h group,I/R24h group and I/R48h group.Rats in pseudo-operation group were undergone laparotomy only.Meanwhile,rats in I/R groups were reperfused with different hours (2,12,24 and 48 hours) following by 30 minutes infrarenal abdominal aorta occlusion induced ischemia.Then the rat hearts in each group were obtained at the specified time points.The activity of SERCA was determined by inorganic phosphorus colorimetry,and gene expression of SERCA was analyzed by reverse transcriptional-PCR.Results:Compared with the pseudo-operation group,the levels of SERCA activity and gene expression in I/R24h group and I/R48h group were down-regulated significantly(P<0.01);but in I/R12h group,SERCA activity was decreased,while gene expression had no statistical difference.And there were no statistical significance about SERCA activity and gene expression in rat heart between the I/R2h group and pseudo-operation group(P>0.05).Conclusions:Infrarenal abdominal aorta occlusion may obviously affect the activity and gene expression of SERCA in rat heart.
Induction of Pseudomonas aeruginosa L-forms with piperacillin
CHEN Deng-yu, CHEN Yi-lin, XU Ping-ping
2010, 35(2): 115-116.
Abstract:
Objective:To observe the induction of Pseudomonas aeruginosa(P.aeruginosa) L-forms with piperacillin.Methods:In plate and liquid media within antibiotic piperacillin,P.aeruginosa was induced into L-forms which would go down to posterity stably.Results:P.aeruginosa was induced to typical and stable L-forms by piperacillin.Conclusions:P.aeruginosa L-form is an important existing form of P.aeruginosa.
The effect of gypenosides on adriamycin-induced diaphragmatic contractile function and mitochondrial ultrastructure
FANG Ying-yan, Ma Li, GUAN Su-dong
2010, 35(2): 117-120.
Abstract:
Objective:To study the influence of gypenosides(GP) on the diaphragmatic contractile function and mitochondrial ultrastructure induced by adriamycin(ADM) in rats.Methods:Twenty-four adult male Sprague-Dawley rats were randomly divided into control(CON)group,adriamycin diaphragm toxicity(ADM) group and adriamycin plus gypenosides(ADM+GP) group.Each group consisted of 8 rats.ADM group and ADM+GP group were injected 2.0 mg/kg ADM intraperitoneally for 6 times every other day,and CON group were injected saline of the same volume and received 250 mg/kg gypenosides per day orally in a dose of 10 ml/kg for four weeks.Meanwhile,pure water was given to ADM group and CON group.The diaphragm contractility was assessed by peak twitch tension(Pt),maximum tetanic tension(Po),time to peak contraction(CT),half relaxation time(1/2RT),and force-frequency curve by in vitro perfusion of diaphragm strips.The activity of SOD,SDH and the content of MDA were determined.The microchondrial ultrastructures of diaphragm were examined by electron microscope.Results:Compared with CON group,Pt and Po of ADM group were lower(P<0.05 to P<0.01),but Pt and Po of ADM+GP group were significantly higher than those of ADM group(P<0.05 to P<0.01); CT and 1/2RT were significant different between ADM+GP group and CON group.Compared with CON group,the tetanic force under the stimulus frequency of 10,20,40,60,80,100 Hz in ADM group and ADM+GP group decreased significantly.Under the stimulus frequency of 80 and 100 Hz,the tetanic force in ADM+GP group was higher than that in ADM group(P<0.05 to P<0.01).The activities of SOD and SDH in ADM group were lower than those in CON group and ADM+GP group(P<0.05 to P<0.01),while the content of MDA in ADM group was remarkably higher(P<0.01).Transmission electron microscopic morphometry showed that gypenosides could ease the diaphragm microchondrial ultrastructural patho-alteration induced by ADM.Conclusions:Gypenosides may lessen the injury of the diaphragmatic contractile function and mitochondrial ultrastructure induced by ADM.
Effect of angiotensin Ⅱ on fibronectin biosynthesis in human renal tubular epithelial cell
CHU La-ping, LIU Jia, WANG Ning-ning, XING Chang-ying
2010, 35(2): 121-123.
Abstract:
Objective:To investigate the effect of angiotensin Ⅱ(AngⅡ) on fibronectin(FN) biosynthesis on human renal tubular epithelial cells.Methods:Cultured human renal tubular epithelial cells were treated with AngⅡ at the concentrations of 10-6 mol/L for 6,12,24,48,72 and 96 hours;and the cells were treated with AngⅡ at the concentrations of 10-8,10-7 and 10-6 mol/L for 96 hours.The FN expression in renal tubular cells was determined by both Western blot and immunofluorescence.Results:Fibronectin synthesis was increased by AngⅡ at a concentration of 10-6 mol/L in the renal tubular epithelial cells.The expression of FN started to increase after 12 hours,and reached the peak after 72 hours.The synthesis of FN was the most obvious at a concentration of 10-6 mol/L,and the following was at 10-7 and 10-8 mol/L.Conclusions:It suggests that AngⅡ stimulates FN secretion of human renal tubular epithelial cells in a dose and time-dependent manner.
Association of metastasis suppressor gene KAI1 expression and lymphangiogenesis with non-small cell lung cancer and its clinical significance
LI Chuan-kui, WANG Zu-yi, WANG Ping, LIU Xue-gang, TANG Zhen, WANG Guo-wen
2010, 35(2): 124-126.
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Objective:To study the synergy between down-regulation or lack of KAI1(one of metastasis suppressor genes) and metastasis of lymph node in non-small cell lung carcinoma(NSCLC).Methods:The expression of KAI1 and Podoplanin which was used to show lymphatic vessel density(LVD) were detected in 68 paraffin sections of NSCLC with immunohistochemistry(EliVision methods),and logistic regression analysis was used to show the relationship between the expression and metastasis of lymph nodes.Results:The positive rates of KAI1 in group one(with metastasis of lymph node) and group two(without metastasis of lymph node) were 30.3% and 88.6%(P<0.01),respectively.The difference of LVD was significant between group one(15.73±0.74) and group two (8.31±0.32)(P<0.01).Logistic regression analysis showed that LVD had an impact on metastasis of lymph node(P<0.05);the odds risk(OR) was 2.065 and the confidence interval of 95% was (1.202,3.547).The down-regulation of KAI1 had no statistical significance(P=0.375),and the confidence interval of 95% was(0.003,8.714).There was no significant synergy between LVD and the expression of KAI1 in metastasis of lymph node(P>0.05).Conclusions:There exists no obvious synergies between down-regulation of KAI1 and lymphangiogenesis in metastasis of lymph node in non-small cell lung carcinoma.
Diagnostic value of plasma brain natriuretic peptide in asymptomatic heart failure
ZHANG Xian-lin, ZHANG Heng, CAI Xin, BAO Zong-ming, WANG Hong-ju, MA Bin, SONG Wei, WANG Feng-chao
2010, 35(2): 127-129.
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Objective:To assess the value of brain natriuretic peptide(BNP) in diagnosis of asymptomatic heart failure(AHF), and to study the relationship between BNP and heart failure.Methods:One hundred and forty subjects were divided into AHF group(50 cases),congestive heart failure(CHF) group(50 cases) and healthy control(40 cases).The plasma BNP was measured, and echocardiogram was performed in all the cases.Exercise treadmill testing was carried on in the patients with AHF and the healthy controls,and the plasma BNP was determined immediately after exercise testing.Multi-variable correlation analysis was used to determine the relationship between BNP and different variables;receiver operating characteristic curves were used to assess the diagnostic accuracy of BNP in detecting AHF.Results:The plasma BNP concentration in CHF group was significantly higher than that in AHF group and control group(P<0.01),but there was no significant difference between AHF group and control group(P>0.05).After exercise testing,the BNP(△BNP) in AHF group increased significantly compared with that in control group(P<0.01).Multi-variable correlation analysis showed that BNP concentrations were positively related to NYHA functional classifications(r=0.534,P<0.01) and negatively related to LVEF(P<0.01).The area under the curve before and after exercise testing and △BNP were 0.653(P<0.05),0.724(P<0.01) and 0.831(P<0.01),respectively.If the value of △BNP was 58.90 pg/ml,the sensitivity and specificity would be 80% and 75% in detecting AHF.Conclusions:BNP is a sensitive and specific diagnostic marker of CHF.Natriuretic peptide concentration is negatively correlated with LVEF and positively with NYHA functional classifications.Plasma BNP can reflect the changes of cardiac function,and can be used to assess the severity of heart failure.BNP combined with exercise testing may enhance the diagnosis of AHF.
2010, 35(2): 129-129.
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Repairing lower nasal defects with superlarge auricle combination tissues
LI Pan-deng, ZHANG Li, GE Shu-xing, LI Xu-wen
2010, 35(2): 130-132.
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Objective:To discuss the repairing of lower nasal defects with superlarge auricle combination tissues.Methods:According to the size of the lower nasal defects,superlarge auricle combination tissues were employed for the repairing.After excising the scar,expanding the interface and making favorable receipt area,the superlarge auricle combination tissues were inserted into the defects with pressure dressing compactly.The sutures were removed after two weeks.Results:The operation was successful in all the 10 patients.The maximum defect area was 2.2 cm×2.0 cm and minimum was 1.5 cm×1.5 cm.The follow-up visit from 1 to 12 months showed that all the patients were satisfied with the size,figure and color of the repaired nasal defects,excepting for 2 patients whose transplantation auricle combination tissues had part of epidermal tripping.Conclusions:Lower nasal defects with areas larger than 1.5 cm×1.5 cm can be repaired by superlarge auricle combination tissues by making favorable receipt area,elaborate operation,proper postoperative pressure dressing,improving microcirculation and promoting nourishment of the transplant tissue flap.
2010, 35(2): 132-133.
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Effect of perflutren injection and cryosurgery under binocular indirect ophthalmoscope in treatment of rhegmatogenous retinal detachment with giant retinal tears
GAO Zi-qing, FANG Li
2010, 35(2): 134-136.
Abstract:
Objective:To observe the effect of perflutren(C3F8) injection and cryosurgery using binocular indirect ophthalmoscope in treatment of rhegmatogenous retinal detachment(RRD) with giant retinal tears.Methods:Twenty-three patients (24 eyes) with RRD received cryosurgery under the binocular indirect ophthalmoscope,and C3F8 was injected into the vitreous cavity;scleral compressing,scleral buckling and subretinal fluid releasing were performed accordingly.Results:Twenty-one eyes had retinal reattachment after one operation,two eyes had retinal reattachment after twice operation,and one eye was performed vitrectomy.Conclusions:C3F8 injection in the vitreous cavity combined with cryosurgery using binocular indirect ophthalmoscope are safe and effective for treatment of rhegmatogenous retinal detachment with giant retinal tears.
Subcutaneous panniculitis-like T-cell lymphoma:one case report and review of the literature
YANG Zhen-zhong, FA Wen, LÜ Yong-fang
2010, 35(2): 136-139.
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Objective:To study the clinicopathologic features,diagnosis and differential diagnosis of subcutaneous panniculitis-like T-cell lymphoma(SPTCL).Methods:One case of SPTCL was examined by HE stainning and immunohistochemistry study.The antibodies which be used were CD3,CD45RO,CD20,CD79a,CD4,CD8,CD30,CD56,CD68 and TIA-1.Results:The case presented as fever,redness,swelling and skin ulcers in left midabdomen and the left inguinal region.Laboratory abnormalities mainly included anemia,leucopenia,thrombocytopenia,elevated liver function tests and hepatosplenomegaly.The histopathology showed a predominant subcutaneous lobular infiltrate with pleomorphic T cells of variable size with irregular and often hyperchromatic nuclei,predominantly with small to medium-sized cells with only scattered large lymphoid cells and rimming of individual adipocytes by atypical lymphocytes.Mitotic figure and karyorrhexis were present.Fat necrosis,hemorrhage,tumor-like necrosis and other cellular responses were also present in the tumor.Immunohistochemistry results showed the tumor cells were positive for CD3,CD45RO,CD8,CD30 and TIA-1,and negative for CD4,CD20,CD79a,CD56 and CD68.The patient died in two months after the onset of the disease.Conclusions:SPTCL is a rare cytotoxic T-cell lymphoma involving primarily in subcutaneous fatty tissues,it has a good prognosis commonly.But if a haemophagocytic syndrome and other syndrome is present,the prognosis maybe be poor.
Clinical analysis of compound trabeculectomy for treatment of glaucoma with persistent high intraocular pressure:a report of 26 cases
DAI Ying-hui, SHANG Ping, LIU Ying-lin, WANG Ai-lian, WANG Jian-feng
2010, 35(2): 140-141.
Abstract:
Objective:To explore the value of compound trabeculectomy in treatment of glaucoma with persistent high intraocular pressure(IOP).Methods:Twenty-six cases (26 eyes) of uncontrolled glaucoma were treated with compound trabeculectomy.Results:The operation was successful in all the cases.No perichoroidal space bleeding or prolapse of vitreous occurred.During the follow-up of 2-12 months,the IOP was less than 21 mmHg in 23 eyes.The vision of 20 eyes was improved.Conclusions:Compound trabeculectomy is safe and effective for glaucoma with persistent high IOP.
Clinical application of the lower abdomen transverse flap pedicled with superior epigastric artery
XIONG Zhu-you, ZHANG Li, XU Jing, WANG Huai-gu, LI Xu-wen, GAO Song, GE Shu-xing
2010, 35(2): 142-144.
Abstract:
Objective:To summarize the clinical application experience of breast reconstruction and chest wound repaired with the lower abdomen transverse flap pedicled with superior epigastric artery.Methods:Ten patients were treated with the lower abdomen transverse flap pedicled with superior epigasric artery.The superior and inferior epigastric atery running in region to bring about central 1/3 part of rectus abdominis muscle and former sheath.Among these patients,5 cases were accepted breast reconstruction immediately after the radical mastectomy,3 cases were received the repair of radioactivity ulcer in chest wall and 2 cases with recurrent breast cancer were repaired wound at stage one after reoperation.Results:The largest area of flap was 25 cm×14 cm,the minimum size was 16 cm×8 cm.All 10 cases of flap were survived and abdominal wounds were sutured by directly draw.No serious complications were occured in patient's chest and abdomen.Fllowed up from 3 months to 3 years,the shape of the breast were satisfied.There had no hernia and obvious weak occurred in abdominal wall.Conclusions:The lower abdomen transverse flap based on the superior epigastric artery and central 1/3 part of rectus abdominal muscle bundle and former sheath has reliable blood supply,large area,simplified operation and it can effectively prevent the occurrence of the abdominal wall hernia and weak.It is an ideal choice for breast reconstruction and chest wall wound repair.
Octreotide combined with compound salvia miltiorrhiza injection for treatment of acute pancreatitis
YANG Qing-feng, ZHANG Xu, ZHOU Lei
2010, 35(2): 145-146.
Abstract:
Objective:To observe the effect of octreotide combined with compound salvia miltiorrhiza injection on patients with acute pancreatitis(AP).Methods:Forty-four patients with AP were randomly divided into control group 23 cases and observation group 21 cases.The control group,in addition to the routine therapy of forbidding food,decompressing stomach and intestines,were given intravenous pump injection of 0.6 mg octreotide in normal saline 48 ml at a rate of 2 ml/h(0.025 mg/h).The observation group received intravenousdrip of compound salvia miltiorrhiza injection of 250 ml besides the above therapy.The time of disappearance of the symptoms,abdominal signs,amylase of urine and blood,and the time of hospital stay were observed and compared.Results:The time of disappearance of amylase of urine and blood after treatment in observation group was shorter than that in the control group(P<0.01).And the time of disappearance of abdominal pain and hospital stay was shorter than that in the control group(P<0.05).Conclusions:Compound salvia miltiorrhiza combined with octreotide can obviously improve the symptoms and signs of patients with AP.
Emergency liver transplantation for treatment of acute hepatic failure with severe abdominal infection:one case report and review of the literature
MA Liang-long, ZHANG Shu-min, YU Lei, CUI Jing-jian
2010, 35(2): 147-149.
Abstract:
Objective:To evaluate the efficacy of emergency liver transplantation on patients with acute hepatic failure(AHF)accompanied by severe abdominal infection.Methods:The clinical data of acute liver transplantation of one patient with AHF and severe abdominal infection were analyzed retrospectively.Results:The liver function of the patient recovered and the infection was brought into control after liver transplantation.During the 3-year follow-up,the liver function of the patient returned to normal,and no rejection occurred;the patient was able to work and lived a normal life.Conclusions:Severe abdominal infection is not absolute contraindication of liver transplantation.The patient with AHF combined with severe abdominal cavity infection may achieve satisfactory effect and live a high quality of life by receiving liver transplantation.
Clinical application of CT-guided percutaneous pulmonary biopsy with needle
QIAN Zhao-xia, HE Yan, GAO Zhong-he, QI Bao-long
2010, 35(2): 149-151.
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Objective:To evaluate the diagnostic significance of percutaneous pulmonary biopsy under CT guidance and to discuss the causes of complication.Methods:CT-guided percutaneous transthoracic incision biopsy was performed in 60 patients with pulmonary masses.The diagnostic accuracy,major complications and the influence factors were reviewed.Results:Aueffective specimens were obtained from the 60 cases(achievement ratio 100%).Final diagnosis was made in 58 cases(diagnostic accuracy 96.6%),including 49 cases of primary pulmonary carcinoma,3 cases of tuberculosis,2 cases of inflammatory pseudotumors,2 cases of metastasis,1 case of sarcoid and 1 case of aspergillosis.The major complications included pneumothorax(13.3%) and pulmonary hemorrhage(16.7%).Pneumothorax and pulmonary hemorrhage were obviously associated with the length of the needle cutting through the air lung(P<0.01).Pneumothorax was not associated with pneumonectasia or location of the lesions(P>0.05).Conclusions:CT-guided pereutaneous transthoracic needle biopsy is a feasible and safe method in diagnosis of pulmonary lesions with high accuracy.Accurate location of the lesions and skillful manipulation are essential in decreasing complications.
Removal of acoustic neuroma via suboccipito-retrosigmoid approach by microsurgery:an analysis of 42 cases
WANG Huai, ZHU Cheng
2010, 35(2): 152-153.
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Objective:To investigate the feasibility of removing the acoustic neuromas via suboccipito-retrosigmoid approach by microsurgery.Methods:The acoustic neuromas in 42 patients were removed by microsurgy via suboccipito-retrosigmoid approach.Results:The tumors were totally removed in 34 cases and partly removed in 8 cases.Anatomic preservation of the facial nerve was achieved in 33 cases and functional preservation in 22 cases (House GradeⅠ-Ⅱ) at discharge.All the cases were followed up for an average of 5 years.The result was good in 29 cases,fair in 10 and poor in 3.Conclusions:It is safe and effective to remove the acoustic neurcoma via suboccipito-retrosigmoid approach using microsurgical technique.
Significance of detecting urine micralbumin and n-acetyl-β-D-glucosaminidase in diagnosis of early renal damage in hypertensive patients
ZHU Qing, CHENG Xun-min, LI Peng
2010, 35(2): 154-155.
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Objective:To investigate the value of detecting microalbumin(mALB) and n-acetyl-β-D-glucosaminidase(NAG) in diagnosis of early renal damage in patients with hypertension.Methods:Mimmunoprecipitation in liquid phase was used to measure the urinary mALB,and the rate method was employed to determine the urinary NAG activity of 78 patients with hypertension,apply agarose gel electrophoresis detect vrine NAG activated.Results:The mALB in 43 cases(55.13%) increased,which was significantly higher than that of conventionl urine protein positive rate of 12.82(P<0.01).The urinary NAG and urinary mALB in the patients with hypertension were significantly higher than those of the control(P<0.01),and tended to rise with the duration of the disease.Conclusions:Urinary mALB and urinary NAG may help to predict the hypertensive renal damage in the early stage.
A surveillance study on bacterial resistance in the Intensive Care Unit
WANG Wei
2010, 35(2): 156-158.
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Objective:To study the antimicrobial resistance of clinical isolates from Intensive Care Unit(ICU).Methods:The specimens of the patients who were in Bengbu Second People's Hospital from Nov.2006 to Jun.2009 were cultured to detect the pathogens.K-B agar diffusion method was used to judge drug sensitivity.Phenotypic confirmatory test was used to detect ESBLs.Results:A total of 33 clinical isolates,including 29 strains (87.9%)of Gram-positive bacilli and 4 strains (12.1%)of Gram-negative bacilli,were collected.Pseudomonas and E.coli was the main microorganism.The most active agent against Gram-negative organisms was Cefoperazone/sulbactam and Vancomycin was the most effective on Gram-positive cocci.Conclusions:The Gram-nagative bacilli was the major pathogen isolated from ICU patients; cefoperazone/sulbactam was the most effective.Pathogens and drug sensitivity monitoring should be enhanced to give guidance for rational use of antibiotics.
Empty follicle syndrome in in vitro fertilization cycles:a report of 3 cases and review of the literature
LUO Li-hua, LIU Yu-sheng, LUAN Hong-bing, JI Jing-juan, ZHENG Sheng-xia
2010, 35(2): 158-161.
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Objective:To explore the causes and coping strategies for empty follicle syndrome(EFS) in vitro fertilization(IVF) cycles.Methods:The clinical data of 3 patients with EFS were analyzed,and the literature was reviewed.Results:The cycles in 2 patients were cancelled due to of EFS; in the succedent cycles,EFS did not occur,but the outcome was not satisfactory;one of them got only 1 embryo(Ⅲ grade) due to descend of ovary reserve function,and the other got 14 oocytes including 11 GⅤoocytes in two cycles.The third patient had EFS at one side ovary,and a second dose of hCG was injected and a second retrieval was scheduled after 24 hours;some follicles had ruptured before the second retrieval,2 oocytes were retrieved and 2 embryos were obtained; transplantation was cancelled due to ovarian hyperstimulation syndrome.Conclusions:EFS may be associated with hCG drug and ovarian dysfunction.Rescue by injecting hCG is effective,but more emphasis should be put on prevention and individual measures.
Operative laparoscopy for ectopic pregnancy with hypovolemic shock
CHEN Li, WANG Huan-hua, ZHONG Ying, WU Li-ling, ZHAO Shan-shan, CHEN Mei
2010, 35(2): 162-163.
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Objective:To explore the efficacy and safety of operative laparoscopy in treatment of ectopic pregnancy with hypovolemic shock.Methods:The clinical data of 71 patients with hypovolemic shock due to ectopic pregnancy were analyzed retrospectively.Forty of them received laparoscope therapy and 31 laparotomy therapy. Results:The operation was successful in all the cases in laparoscopic group and no one was converted to laparotomy.The intra-abdominal blood loss and operating time between the two groups had no statistical difference(P>0.05).The time of anus exsufflation in laparoscope therapy was significant shorter than that in laparotomy therapy(P<0.01).Conclusions:Operative laparoscopy is safe and effective for treatment of ectopic pregnancy with hypovolemic shock.
Colposcopy in diagnosis of cervical disease
ZHU Yun-ju, WEI Ming-xiu
2010, 35(2): 164-165.
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Objective:To assess the clinical value of colposcopy in diagnosis of cervical disease.Methods:Two thousand one hundred patients with cervical disease were examined by colposcopy,and 1 280 of them received positioning biopsy.Results:Among the 1 280 cases having gone through histopathologic examination,55 cases were proved to have cervical intraepithelial neoplasia(CIN 1-3),9 cases cervical infiltrating tumor and 228 human papilloma virus(HPV) infection.Conclusions:Colposcopy is of value in early diagnosis of cervical carcinoma,CIN and HPV infection.
Short-term insulin intensive therapy for inflammation in newly-diagnosed type 2 diabetics
LI Zhi-qiang, YE Shan-dong
2010, 35(2): 166-167.
Abstract:
Objective:To observe the effect of short-term insulin intensive therapy on the inflammation in newly-diagnosed type 2 diabetics.Methods:Twenty-one newly-diagnosed type 2 diabetic patients with fasting blood sugar(FBG)>11.1 mmol/L were treated by short-term insulin intensive therapy for 2 weeks.The fasting serum tumor necrosis factor-α(TNF-α) and CRP were compared before and after the therapy,and their relationship with △I30'/△G30',Homa-B function index and Homa-IR were observed.Results:After 2 weeks of treatment,the CRP,TNF-α and Hama-IR decreased significantly(P<0.01),and △I30'/△G30' increased significantly(P<0.05); Homa B was obviously increased (P<0.01);serum CRP and TNF-α was greatly related with Homa B function index and Hama-IR (P<0.05).Conclusions:Short-term intensive therapy may control the markedly increased blood glucose in newly-diagnosed type 2 diabetic patients and alleviate their inflammation reaction.
Clinical analysis of 68 subjects with type 2 diabetes mellitus combined with atherosclerotic renal artery stenosis
CHEN Jing
2010, 35(2): 168-170.
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Objective:To assess the predictor factors for atherosclerotic renal artery stenosis(ARAS) in type 2 diabetes mellitus.Methods:A total of 68 subjects with type 2 diabetes mellitus combined with ARAS confirmed by intra-arterial angiography or magnetic resonance angipgraphy,and 44 subjects with no ARAS were included in the study.The patients' age,sex,duration of diabetes and hypertention,blood lipid,glycosylated hemoglobin,creatinine,uric acid,and other atherosclerotic diseases were analyzed statistically.Results:There were significant differences in age,creatinine,uric acid and other atherosclerotic diseases between the two groups.ARAS was positively associated with age,creatinine,uric acid and other atherosclerotic diseases(P<0.05-P<0.01),and negatively associated with high density lipoprotein-C(P<0.05).Conclusions:Age,high density lipoprotein-C,blood creatinine,uric acid and other atherosclerotic diseases are predictor factors for ARAS.
2010, 35(2): 170-173.
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2010, 35(2): 173-175.
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2010, 35(2): 175-176.
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2010, 35(2): 176-178.
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Detection of human papilloma virus infection in patients with condyloma acuminatum
WANG Cheng-hu
2010, 35(2): 178-180.
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Objective:To comprehend the infect condition of human papilloma virus(HPV) in patients with condyloma acuminatum(CA).Methods:The real-time FQ-PCR method was established to detect HPV type 6,11,16 and 18 in 68 samples from patients with condyloma acuminatum and 160 samples from subclinical patients.Results:The positive rates of male and female were 78.99%and 77.78%,respectively,there was no stastical significance(P>0.05).Detection rates of CA tissues and subclinical tissues were 95.59% and 71.25%,respectively,with the stastical significance(P<0.01).Among the 179 HPV positive patients,76.54% were infected with HPV type 6 and type 11, 8.94% were infected with HPV type 16 and type 18, 14.52%were mixed infection with HPV type 6,11,16 and 18.Conclusions:The HPV infective rate in male is as same as in female; and the detection rate of CA is higher than in other samples; HPV type 6 and type 11 infection are the main reasons in our region.
2010, 35(2): 180-182.
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2010, 35(2): 182-184.
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CT and MRI diagnosis of primary liposarcoma of extremities and trunk
HU Shu-dong, WANG Ya-fei, TAN Ji-shan, CHEN Ye-rong, WEI Zhong-hua, LÜ Wei-fu
2010, 35(2): 185-187.
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Objective:To analyze the CT and MRI features of liposarcoma of the extremities and trunk for improving the diagnosis of the disease.Methods:The CT and MRI findings of 12 cases of primary liposarcoma confirmed by operation and pathology were analyzed retrospectively.Seven cases were examined by CT,11 cases by MRI,and 6 cases by both CT and MRI.Results:Among the 12 cases,6 were well differentiated liposarcoma,2 sclerosing liposarcoma,3 myxoid iposarcoma,2 pleomorphic and 1 was dedifferentiated liposarcoma.Seven cases were irregularly margined and five cases regularly margined.The mean diameter of the lesions ranged from 6.1 to 19.9 cm.Well differentiated liposarcom contained a large amount of mature fat.CT and MRI showed fat tissue which was well defined,and homogeneous in density and signal intensity(SI).Myxoid liposarcoma consisted mainly of myxoid matrix,containing a few well differentiated proliferating lipoblasts;CT and MRI demonstrated no or little fat with irregular density and mildly inhomogeneous SI.Pleomorphic liposarcoma had no characteristic of fat tissue,and the adjacent structures were infiltrated and edematous with apparently inhomogeneous density and SI.Dedifferentiated liposarcoma had a pretty large volume with apparently inhomogeneous density and SI.The enhancement was highly intensified.Conclusions:CT and MRI can reflect the histological features of liposarcoma of the extremities and trunk,and demonstrate the exact boundaries of tumors,the actual area and surrounding tissues.The degree of histology differentiation and malignancy can be evaluated on the basis of CT and MRI findings of liposarcoma.
2010, 35(2): 187-188.
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An exploration in teaching ideological and political theory courses in medical universities
XIONG Yun-bo, QI Yu-long, QI Mei
2010, 35(2): 189-191.
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Objective:To explore a practical teaching pattern for ideological and political theory courses in medical universities and to improve the teaching effects.Methods:Various forms of practical teaching activities were carried out and the experience was summarized.Results:A practical teaching pattern for ideological and political theory courses which adapts to medical universities had been explored,and better teaching effects were achieved.Conclusions:Constant exploration and improvement on the teaching of ideological and political theory courses may achieve better teaching effects.
2010, 35(2): 191-193.
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Effect of adaptability instruction on degree of comfort in patient after coronary angiography
YU Ji-ying, ZHANG Li-hua, TU Min
2010, 35(2): 194-196.
Abstract:
Objective:To investigate the influence of adaptability instruction on damped tolerance and degree of comfort in patients after coronary angiography.Methods:One hundred and twenty-one patients with coronary arteriongraphy were divided into two groups randomly.Sixty-one patients(control group)with routine nursing,60 patients(treated group)with routine nursing combining with strengthening adaptability instruction.Nursing effect was observed with the degree of anxiety,the condition of somnus,the value of urination and the degree of lumbar and back pain.Results:The degree of anxiety,the derangement of somnus,the value of urination,the degree of lumbar and back pain of these two groups were obviously different by analysis of statistics(P<0.05 to P<0.001).Conclusions:The adaptability instruction could improve the comfort of patients who lying in bed after coronary angiography and decreasing the postoperative complications.
2010, 35(2): 196-197.
Abstract:
2010, 35(2): 198-200.
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2010, 35(2): 200-201.
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2010, 35(2): 202-203.
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2010, 35(2): 204-205.
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2010, 35(2): 206-208.
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2010, 35(2): 208-210.
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2010, 35(2): 211-214.
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2010, 35(2): 214-217.
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