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2010 Vol. 35, No. 11
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2010, 35(11): 1081-1084.
Abstract:
Objective:To investigate the effect of captopril on collagen type Ⅰ and type Ⅲ and their mRNA expressions in abdominal aortic banding model rats.Methods:Myocardial fibrosis rat model was established by partially banding abdominal aorta with silver clip (inside diameter 0.7 mm) according to Doering's method.Optical density values of collagen typeⅠand type Ⅲ were measured by immunohistochemistry staining after 8 weeks.The mRNA expressions of collagen typeⅠand type Ⅲ were analyzed by real-time PCR amplification.Results:In the 8th week,compared with sham operation group,the average optical density value and mRNA expressions of collagen type Ⅰ and type Ⅲ were increased obviously in model group (P<0.01).The immunohistochemistry staining displayed that collagen type Ⅰand type Ⅲ were deposited,thicken and confused in myocardium stroma;and the quantity of collagen was decreased obviously in model group.Conclusions:The quantity of collagen type Ⅰ and type Ⅲ and the related mRNA expressions were increased in myocardical fibrosis induced by abdominal aortic banding in rats;captopril could delay even reverse the process of myocardial fibrosis.
Objective:To investigate the effect of captopril on collagen type Ⅰ and type Ⅲ and their mRNA expressions in abdominal aortic banding model rats.Methods:Myocardial fibrosis rat model was established by partially banding abdominal aorta with silver clip (inside diameter 0.7 mm) according to Doering's method.Optical density values of collagen typeⅠand type Ⅲ were measured by immunohistochemistry staining after 8 weeks.The mRNA expressions of collagen typeⅠand type Ⅲ were analyzed by real-time PCR amplification.Results:In the 8th week,compared with sham operation group,the average optical density value and mRNA expressions of collagen type Ⅰ and type Ⅲ were increased obviously in model group (P<0.01).The immunohistochemistry staining displayed that collagen type Ⅰand type Ⅲ were deposited,thicken and confused in myocardium stroma;and the quantity of collagen was decreased obviously in model group.Conclusions:The quantity of collagen type Ⅰ and type Ⅲ and the related mRNA expressions were increased in myocardical fibrosis induced by abdominal aortic banding in rats;captopril could delay even reverse the process of myocardial fibrosis.
2010, 35(11): 1084-1087.
Abstract:
Objective:To study the role of extracellular regulated protein kinases (ERK-1/2) in vein grafts.Methods:Forty-five adult rabbits were randomly divided into control group,VG group and VG/UO group.Carotid artery bypasses were performed using reversed autologous external jugular vein.A segment of each sample was analyzed with western blot.Results:Intimal hyperplasia was observed 28 days after the operation in group VG.The reversed autologous external jugular vein grafts resulted in activation of ERK-1/2 with stronger activation occurring at 3 h and at 3 d.Proliferating cell nuclear antigen (PCNA) began to express 3 h after the operation and lasted for 28 d.The activation of ERK-1/2 in group VG/UO was significant inhibited after the application of UO126,and there was no peak of activation detected.Conclusions:ERK-1/2 activation may be the key point in the process of intimal hyperplasia.Inhibition of the ERK-1/2 pathway inhibits intimal hyperplasia,and therefore,results in inhibition of the late events.
Objective:To study the role of extracellular regulated protein kinases (ERK-1/2) in vein grafts.Methods:Forty-five adult rabbits were randomly divided into control group,VG group and VG/UO group.Carotid artery bypasses were performed using reversed autologous external jugular vein.A segment of each sample was analyzed with western blot.Results:Intimal hyperplasia was observed 28 days after the operation in group VG.The reversed autologous external jugular vein grafts resulted in activation of ERK-1/2 with stronger activation occurring at 3 h and at 3 d.Proliferating cell nuclear antigen (PCNA) began to express 3 h after the operation and lasted for 28 d.The activation of ERK-1/2 in group VG/UO was significant inhibited after the application of UO126,and there was no peak of activation detected.Conclusions:ERK-1/2 activation may be the key point in the process of intimal hyperplasia.Inhibition of the ERK-1/2 pathway inhibits intimal hyperplasia,and therefore,results in inhibition of the late events.
2010, 35(11): 1087-1090.
Abstract:
Objective:To construct a kind of extracellular matrix scaffold and investigate whether it can influence the expression of neurotrophins in rat olfactory ensheathing cells.Methods:Mixed fibrinogen,laminin and fibronectin proportionally,then added fresh rat plasma to construct scaffold.Plated the rat olfactory ensheathing cells (OEC) on scaffold and then observed the influence of scaffold on proliferation and neurotrophin expression of OEC.Results:Rat OEC adhered to scaffold easily,proliferated quickly and extended long processes.Immunofluorescence and western blotting showed rat OEC on scaffold could produce more neurotrophins than those on glass.Conclusions:Extracellular matrix scaffold can promote proliferation of rat OEC and promote the production of neurotrophins.
Objective:To construct a kind of extracellular matrix scaffold and investigate whether it can influence the expression of neurotrophins in rat olfactory ensheathing cells.Methods:Mixed fibrinogen,laminin and fibronectin proportionally,then added fresh rat plasma to construct scaffold.Plated the rat olfactory ensheathing cells (OEC) on scaffold and then observed the influence of scaffold on proliferation and neurotrophin expression of OEC.Results:Rat OEC adhered to scaffold easily,proliferated quickly and extended long processes.Immunofluorescence and western blotting showed rat OEC on scaffold could produce more neurotrophins than those on glass.Conclusions:Extracellular matrix scaffold can promote proliferation of rat OEC and promote the production of neurotrophins.
2010, 35(11): 1091-1093.
Abstract:
Objective:To observe the outcome of early repair of cleft lip and simultaneous correction of nasal deformities.Methods:The Millard procedure was used to repair the unilateral cleft lip.The greater alar cartilage and nasalis were repositioned to the normal anatomical position through the incisions.The deviated septum and columella were corrected by cutting the abnormal attachment of the orbicularis oris muscle to the anterior nasal spine.The alar cartilage of the deformed side was upgraded to the same height of the normal side and fixed up with the mattress sutures.Results:Twenty-six infants were treated with this method.The follow-up lasted from six to fourteen months.The results were satisfactory.Conclusions:It is feasible to repair unilateral cleft lip and to correct nasal deformity simultaneously,which can reach real-time results and good long-term efficacy.This technique can eliminate the severe cleft nasal deformity,and reduce the re-operation rate and surgical difficulty.It is recommended for the treatment of unilateral cleft lip with nasal deformity.
Objective:To observe the outcome of early repair of cleft lip and simultaneous correction of nasal deformities.Methods:The Millard procedure was used to repair the unilateral cleft lip.The greater alar cartilage and nasalis were repositioned to the normal anatomical position through the incisions.The deviated septum and columella were corrected by cutting the abnormal attachment of the orbicularis oris muscle to the anterior nasal spine.The alar cartilage of the deformed side was upgraded to the same height of the normal side and fixed up with the mattress sutures.Results:Twenty-six infants were treated with this method.The follow-up lasted from six to fourteen months.The results were satisfactory.Conclusions:It is feasible to repair unilateral cleft lip and to correct nasal deformity simultaneously,which can reach real-time results and good long-term efficacy.This technique can eliminate the severe cleft nasal deformity,and reduce the re-operation rate and surgical difficulty.It is recommended for the treatment of unilateral cleft lip with nasal deformity.
2010, 35(11): 1093-1095.
Abstract:
Objective:To investigate the serological characteristics and immunological features of primary Sjogren's syndrome (pSS).Methods:A total of 62 patients with pSS were studied.All the cases was were diagnosed according to the American European consensus criteria (AECC) of 2002.The main clinical and immunological features were analyzed.Results:The common initial clinical symptoms included xerostomia,xerophthalmia,hypokalemia and arthralgia.Reynaud phenomenon was rarely seen.Positive ANA and anti-SSA52 (+) antibodies were frequently detected (83.9% and 85.5%).The rates of RF titer and IgG levels were 72.6% and 79.0% respectively.The percentage of CD4+ T cells and the ration of CD4+/CD8+ T cells in peripheral blood of pSS patients were lower than that of healthy controls.The expression rate of CD16+56+ in peripheral bloods of pSS patients (5.8±2.6)%were lower than that of reference value (10.0±3.8)%.Conclusions:Anti-SSA-52 (+) antibody is a frequent immunological marker among pSS patients.Low CD4+/CD8+ T-lymphocyte ratio may be a significant risk factor for the development of lymphoma in pSS.Lower expression of CD16+56+ determines the extent to which the NK cells lose the immune supervision,which may increase the incidence of lymphoma in pSS patients.
Objective:To investigate the serological characteristics and immunological features of primary Sjogren's syndrome (pSS).Methods:A total of 62 patients with pSS were studied.All the cases was were diagnosed according to the American European consensus criteria (AECC) of 2002.The main clinical and immunological features were analyzed.Results:The common initial clinical symptoms included xerostomia,xerophthalmia,hypokalemia and arthralgia.Reynaud phenomenon was rarely seen.Positive ANA and anti-SSA52 (+) antibodies were frequently detected (83.9% and 85.5%).The rates of RF titer and IgG levels were 72.6% and 79.0% respectively.The percentage of CD4+ T cells and the ration of CD4+/CD8+ T cells in peripheral blood of pSS patients were lower than that of healthy controls.The expression rate of CD16+56+ in peripheral bloods of pSS patients (5.8±2.6)%were lower than that of reference value (10.0±3.8)%.Conclusions:Anti-SSA-52 (+) antibody is a frequent immunological marker among pSS patients.Low CD4+/CD8+ T-lymphocyte ratio may be a significant risk factor for the development of lymphoma in pSS.Lower expression of CD16+56+ determines the extent to which the NK cells lose the immune supervision,which may increase the incidence of lymphoma in pSS patients.
2010, 35(11): 1096-1098.
Abstract:
Objective:To compare the clinical effect of elderly patients with osteoporotic intertrochanteric fracture with the different treatment.Methods:Two hundred and sixty-eight old patients with osteoporotic intertrochanteric fracture were investigated retrospectively.All patients were divided into expectant treatment group (68 cases),the hollow nail group (36 cases),Richard nail group (136 cases),and proximal femoral nail (PFN) (28 cases).Results:There were 200 patients that underwent the surgical treatment.One hundred and ninty-seven patients received fracture healing and 3 patients died.The average healing time was 2.6 months.Meanwhile,in the conservative treatment group 62 patients received fracture healing and 22 patients died.The average healing time was 4.2 months.The effect of the surgical treatment is better than the conservative treatment (P<0.01).There were no coxa vara,the internal fixation bending,cortical bone screw implant rupture in the PFN and Richard screw fixation treatment group.The coxa vara occurred in 17 patients with cannulated screws fixation.Conclusions:Elderly patients with osteoporotic intertrochanteric fractures should be treated on the basis of the body condition as soon as possible.The internal fixation treatment should be given priority.The ideal internal fixation should be to reduce complications,reduce bone loss in the intertrochanteric area,strongly sustaining,fracture healing,functional recovery.
Objective:To compare the clinical effect of elderly patients with osteoporotic intertrochanteric fracture with the different treatment.Methods:Two hundred and sixty-eight old patients with osteoporotic intertrochanteric fracture were investigated retrospectively.All patients were divided into expectant treatment group (68 cases),the hollow nail group (36 cases),Richard nail group (136 cases),and proximal femoral nail (PFN) (28 cases).Results:There were 200 patients that underwent the surgical treatment.One hundred and ninty-seven patients received fracture healing and 3 patients died.The average healing time was 2.6 months.Meanwhile,in the conservative treatment group 62 patients received fracture healing and 22 patients died.The average healing time was 4.2 months.The effect of the surgical treatment is better than the conservative treatment (P<0.01).There were no coxa vara,the internal fixation bending,cortical bone screw implant rupture in the PFN and Richard screw fixation treatment group.The coxa vara occurred in 17 patients with cannulated screws fixation.Conclusions:Elderly patients with osteoporotic intertrochanteric fractures should be treated on the basis of the body condition as soon as possible.The internal fixation treatment should be given priority.The ideal internal fixation should be to reduce complications,reduce bone loss in the intertrochanteric area,strongly sustaining,fracture healing,functional recovery.
2010, 35(11): 1098-1100.
Abstract:
Objective:To summarize and analyze the clinical features of the trachea squamous papilloma so as to arouse the awareness of the disease and make early diagnosis and treatment.Methods:The clinical data of one case of trachea multiple squamous papilloma (including the case history,clinical manifestations,chest CT photos,bronchoscope and pathology results) were analyzed retrospectively and reviewed with literature.Results:The characteristic symptoms of tracheal papilloma were dyspnea,coughing and expectorating "meat-like" material;hemoptysis could also be seen.The chest CT,three-dimensional reconstruction of the trachea and bronchoscopy were great value in diagnosis of the disease.Conclusions:As tracheal papilloma is rarely seen,it is easy to be misdiagnosed.Interventional therapy under electron-bronchoscope is safe and effective for treatment of the disease.
Objective:To summarize and analyze the clinical features of the trachea squamous papilloma so as to arouse the awareness of the disease and make early diagnosis and treatment.Methods:The clinical data of one case of trachea multiple squamous papilloma (including the case history,clinical manifestations,chest CT photos,bronchoscope and pathology results) were analyzed retrospectively and reviewed with literature.Results:The characteristic symptoms of tracheal papilloma were dyspnea,coughing and expectorating "meat-like" material;hemoptysis could also be seen.The chest CT,three-dimensional reconstruction of the trachea and bronchoscopy were great value in diagnosis of the disease.Conclusions:As tracheal papilloma is rarely seen,it is easy to be misdiagnosed.Interventional therapy under electron-bronchoscope is safe and effective for treatment of the disease.
2010, 35(11): 1101-1103.
Abstract:
Objective:To investigate the correlation between health belief and behavior of medical compliance in hypertensive disorder complicating pregnancy patients.Methods:A random sampling method was used in this study.One hundred hypertensive disorder complicating pregnancy patients were investigated with three contents,including demographic information,questionnaire of health belief and behavior of medical compliance about hypertensive disorder complicating pregnancy patients.The statistical package for Social Science (SPSS) 11.0 was used for data analysis.Results:The mean score of health belief with hypertensive disorder complicating pregnancy was 67.94±6.514,the mean score of behavior of medical compliance was 7.87±1.871,there was a significantly positive correlation not only between health belief and behavior of medical compliance but also between health belief and every aspect of behavior of medical compliance in hypertensive disorder complicating pregnancy patients (P<0.01).Conclusions:The behavior of medical compliance influences the effect of treatment of hypertensive disorder complicating pregnancy patients.So the nurse should pay more attention to the behavior of medical compliance and the associated psychological factors of hypertensive disorder complicating pregnancy patients and take more effective measures systematically to reduce or delay the occurrence of hypertensive disorder complicating pregnancy.
Objective:To investigate the correlation between health belief and behavior of medical compliance in hypertensive disorder complicating pregnancy patients.Methods:A random sampling method was used in this study.One hundred hypertensive disorder complicating pregnancy patients were investigated with three contents,including demographic information,questionnaire of health belief and behavior of medical compliance about hypertensive disorder complicating pregnancy patients.The statistical package for Social Science (SPSS) 11.0 was used for data analysis.Results:The mean score of health belief with hypertensive disorder complicating pregnancy was 67.94±6.514,the mean score of behavior of medical compliance was 7.87±1.871,there was a significantly positive correlation not only between health belief and behavior of medical compliance but also between health belief and every aspect of behavior of medical compliance in hypertensive disorder complicating pregnancy patients (P<0.01).Conclusions:The behavior of medical compliance influences the effect of treatment of hypertensive disorder complicating pregnancy patients.So the nurse should pay more attention to the behavior of medical compliance and the associated psychological factors of hypertensive disorder complicating pregnancy patients and take more effective measures systematically to reduce or delay the occurrence of hypertensive disorder complicating pregnancy.
2010, 35(11): 1104-1105,1109.
Abstract:
Objective:To investigate the value of cardiac troponin (CTn-Ⅰ) in the diagnosis of brain-heart syndrome in acute cerebrovascular disease.Methods:The venous blood of 232 subjects were taken within 12 h after hospitalization,and the levels of CTn-Ⅰ,creatine kinase (CK),creatine kinase-MB (CK-MB),lactate dehydrogenase (LDH) and alanine transaminase (AST) were detected repeatedly every 24-48 h for 2-9 times.Results:In these subjects,the results showed if the level of CTn-Ⅰ was increased,the levels of CK,CK-MB,LDH and AST were all increased at the same time.Although in partial subjects,the levels of CK,CK-MB,AST,LDH were increased,but CTn-Ⅰ remained normal.Elderly severe subjects with hypertension often had high occurence for abnormal CTn-Ⅰ,which was related to prognosis,but not associated with characteristic of lesions.Conclusions:CTn-Ⅰ is more sensitive for diagnosis of brain-heart syndrome in contrast to CK,CK-MB,LDH and AST.And elderly severe subjects with hypertension are easy to have brain-heart syndrome,which is not associated with characteristic of lesions.
Objective:To investigate the value of cardiac troponin (CTn-Ⅰ) in the diagnosis of brain-heart syndrome in acute cerebrovascular disease.Methods:The venous blood of 232 subjects were taken within 12 h after hospitalization,and the levels of CTn-Ⅰ,creatine kinase (CK),creatine kinase-MB (CK-MB),lactate dehydrogenase (LDH) and alanine transaminase (AST) were detected repeatedly every 24-48 h for 2-9 times.Results:In these subjects,the results showed if the level of CTn-Ⅰ was increased,the levels of CK,CK-MB,LDH and AST were all increased at the same time.Although in partial subjects,the levels of CK,CK-MB,AST,LDH were increased,but CTn-Ⅰ remained normal.Elderly severe subjects with hypertension often had high occurence for abnormal CTn-Ⅰ,which was related to prognosis,but not associated with characteristic of lesions.Conclusions:CTn-Ⅰ is more sensitive for diagnosis of brain-heart syndrome in contrast to CK,CK-MB,LDH and AST.And elderly severe subjects with hypertension are easy to have brain-heart syndrome,which is not associated with characteristic of lesions.
2010, 35(11): 1106-1109.
Abstract:
Objective:To evaluate systematically the efficacy and safety of nimodipine injection in the treatment of patients suffering from cerebral vasospasm after subarachnoid hemorrhage.Methods:By overall collecting the related literature of controlled clinical trials about nimodipine injection for the treatment of cerebral vasospasm after subarachnoid hemorrhage from 1994 to 2007,Meta analysis was conducted by means of Review with Manager 4.2 software.Results:The homogenecity test of 16 selected clinical research showed that they had homogenicity (P>0.05).The result of Meta analysis showed that the rate of cerebral vasospasm and mortality rate after subarachnoid hemorrhage was much lower in nimodipine group than the control group (P<0.000001).The rate of rehaemorrhagia had no difference between the two groups (P=0.17).Conclusions:The evidence available shows that nimodipine is effective and safe in the treatment of cerebral vasospasm after subarachnoid hemorrhage and does not raise the risk of re-hemorrhage.
Objective:To evaluate systematically the efficacy and safety of nimodipine injection in the treatment of patients suffering from cerebral vasospasm after subarachnoid hemorrhage.Methods:By overall collecting the related literature of controlled clinical trials about nimodipine injection for the treatment of cerebral vasospasm after subarachnoid hemorrhage from 1994 to 2007,Meta analysis was conducted by means of Review with Manager 4.2 software.Results:The homogenecity test of 16 selected clinical research showed that they had homogenicity (P>0.05).The result of Meta analysis showed that the rate of cerebral vasospasm and mortality rate after subarachnoid hemorrhage was much lower in nimodipine group than the control group (P<0.000001).The rate of rehaemorrhagia had no difference between the two groups (P=0.17).Conclusions:The evidence available shows that nimodipine is effective and safe in the treatment of cerebral vasospasm after subarachnoid hemorrhage and does not raise the risk of re-hemorrhage.
2010, 35(11): 1110-1112.
Abstract:
Objective:To investigate the causes of fever of unknown origin (FUO).Methods:The clinical data of 108 cases fulfilled the criteria of FUO were retrospectively analyzed in our hospital.Results:The diagnosis of FUO was clarified in 97 cases out of all 108 cases.The causes were as follows:Fifty-eight cases were suffered from infectious diseases,in which,tuberculosis was 19 cases.Eighteen cases were suffered from connective tissue diseases,in which,adult Stills disease was 7 cases.Sixteen cases were suffered from tumors,in which,lymphoma was 6 cases.Other causes were found in 5 cases.Conclusions:Infectious diseases,especially tuberculosis,are the most common causes of FUO.Connective tissue diseases and tumors are other major causes.
Objective:To investigate the causes of fever of unknown origin (FUO).Methods:The clinical data of 108 cases fulfilled the criteria of FUO were retrospectively analyzed in our hospital.Results:The diagnosis of FUO was clarified in 97 cases out of all 108 cases.The causes were as follows:Fifty-eight cases were suffered from infectious diseases,in which,tuberculosis was 19 cases.Eighteen cases were suffered from connective tissue diseases,in which,adult Stills disease was 7 cases.Sixteen cases were suffered from tumors,in which,lymphoma was 6 cases.Other causes were found in 5 cases.Conclusions:Infectious diseases,especially tuberculosis,are the most common causes of FUO.Connective tissue diseases and tumors are other major causes.
2010, 35(11): 1112-1113.
Abstract:
Objective:To analyze the causes of obstetric hysterectomy and explore how to reduce the possibility of obstetric hysterectomy.Methods:The clinical data of sixteen cases of obstetric hysterectomy were analyzed retrospectively.Eleven cases were operated with total hysterectomy and 5 cases with subtotal hysterectomy.Results:The blood loss before and during operative period was 400-6 550 ml,eleven cases were recovered from illness,3 cases had a wound hematoma drainage or second sutures healing.Two cases were died.Conclusions:Obstetric hysterectomy is one of effective treatments for acute bleeding parturient woman.It may effectively reduce the incidence of obstetric hysterectomy to keep up the birth control and pregnant woman guardianship,prevent and control obstetrics complications positively,and raise personnel technical level of the medical worker in the basic obstetrics department.
Objective:To analyze the causes of obstetric hysterectomy and explore how to reduce the possibility of obstetric hysterectomy.Methods:The clinical data of sixteen cases of obstetric hysterectomy were analyzed retrospectively.Eleven cases were operated with total hysterectomy and 5 cases with subtotal hysterectomy.Results:The blood loss before and during operative period was 400-6 550 ml,eleven cases were recovered from illness,3 cases had a wound hematoma drainage or second sutures healing.Two cases were died.Conclusions:Obstetric hysterectomy is one of effective treatments for acute bleeding parturient woman.It may effectively reduce the incidence of obstetric hysterectomy to keep up the birth control and pregnant woman guardianship,prevent and control obstetrics complications positively,and raise personnel technical level of the medical worker in the basic obstetrics department.
2010, 35(11): 1114-1115.
Abstract:
Objective:To study the clinical therapeutic effect in patients suffered from Barrett's esophagus.Methods:Fifty-four patients who suffered from Barrett's esophagus were divided into three groups:control group,the group treated with drugs only and the group treated with argon plasma coagulation (APC) and drugs.The total remission rate,the changes of mucous membranes of Barrett's esophagus in endoscope and the adverse effect were studied in different groups.Results:The total remission rates in the group treated with drugs only and the group treated with APC and drugs were increased compared to control group (P<0.01).And the effect in group with APC and drugs was more significant than in group with drugs only.There was no conspicuous change of mucous membranes of Barrett's esophagus in control group and the group treated with drugs only,but mucous membranes were disappeared in the group treated with APC and drugs.No serious adverse effect was observed in the three groups.Conclusions:It is a safety and effective method to treat Barrett's esophagus with APC and drugs.
Objective:To study the clinical therapeutic effect in patients suffered from Barrett's esophagus.Methods:Fifty-four patients who suffered from Barrett's esophagus were divided into three groups:control group,the group treated with drugs only and the group treated with argon plasma coagulation (APC) and drugs.The total remission rate,the changes of mucous membranes of Barrett's esophagus in endoscope and the adverse effect were studied in different groups.Results:The total remission rates in the group treated with drugs only and the group treated with APC and drugs were increased compared to control group (P<0.01).And the effect in group with APC and drugs was more significant than in group with drugs only.There was no conspicuous change of mucous membranes of Barrett's esophagus in control group and the group treated with drugs only,but mucous membranes were disappeared in the group treated with APC and drugs.No serious adverse effect was observed in the three groups.Conclusions:It is a safety and effective method to treat Barrett's esophagus with APC and drugs.
2010, 35(11): 1116-1118.
Abstract:
Objective:To explore the application feasibility of etomidate emulsions combined with sufentanil continue pumping in laparoscopic cholecystectomy (LC).Methods:Fifty patients in ASA Ⅰ-Ⅱ who undergone elective LC were randomly divided into trial group (E group,n=25) and control group (P group,n=25).The patients in E group were pumped continuously with etomidate emulsions 0.6-0.9 mg·kg-1·h-1 combined with sufentanil 0.2 μg·kg-1·h-1·The patients in P group were pumped continuously with propofol 4-6 mg·kg-1·h-1 combined with sufentanil 0.2 μg·kg-1·h-1·All patients in these two groups were continuous infused with rocuronium 5-6 μg·kg-1·min-1.Heart rate (HR),systolic blood pressure (SBP),diastolic blood pressure (DBP),postoperative decannulation time,postoperative recovery condition,state of consciousness post anesthesia care unit leave time,restlessness,postoperative nausea and vomiting,cough,laryngospasm,choking intraoperative awareness as adverse reaction conditions were recorded before narcotic induction narcotic induction (T0),immediately (T1),during tracheal intubation (T2),gasless 5 min (T3),15 min (T4),after the lift gasless 5 min (T5).Results:The hemodynamics indexes at all time points between the two groups were no statistical significance.The detubation time,consciousness recovery and the incidence rate of adverse reactions between these two groups were no statistical significance.Conclusions:Etomidate emulsions sufentanil compound can be used safely in LC anesthesia.
Objective:To explore the application feasibility of etomidate emulsions combined with sufentanil continue pumping in laparoscopic cholecystectomy (LC).Methods:Fifty patients in ASA Ⅰ-Ⅱ who undergone elective LC were randomly divided into trial group (E group,n=25) and control group (P group,n=25).The patients in E group were pumped continuously with etomidate emulsions 0.6-0.9 mg·kg-1·h-1 combined with sufentanil 0.2 μg·kg-1·h-1·The patients in P group were pumped continuously with propofol 4-6 mg·kg-1·h-1 combined with sufentanil 0.2 μg·kg-1·h-1·All patients in these two groups were continuous infused with rocuronium 5-6 μg·kg-1·min-1.Heart rate (HR),systolic blood pressure (SBP),diastolic blood pressure (DBP),postoperative decannulation time,postoperative recovery condition,state of consciousness post anesthesia care unit leave time,restlessness,postoperative nausea and vomiting,cough,laryngospasm,choking intraoperative awareness as adverse reaction conditions were recorded before narcotic induction narcotic induction (T0),immediately (T1),during tracheal intubation (T2),gasless 5 min (T3),15 min (T4),after the lift gasless 5 min (T5).Results:The hemodynamics indexes at all time points between the two groups were no statistical significance.The detubation time,consciousness recovery and the incidence rate of adverse reactions between these two groups were no statistical significance.Conclusions:Etomidate emulsions sufentanil compound can be used safely in LC anesthesia.
2010, 35(11): 1119-1120.
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Objective:To investigate the therapeutic efficiency of open reduction internal fixation with locking compression plate on comminuted distal radial fractures.Methods:Twenty-one cases of comminuted distal radial fractures that failed with closed reduction were treated with open reduction.internal fixation with locking compression plate.The healing of bone and long-term functional result were followed up.Results:All cases were followed up between 6-13 months.All the fractures were united and the the healing time was between 49-56 days.There were no complications such as infection,nonunion,breakage of the implants,or restriction of finger extension.According to the modified Green and O'Brien criteria of fracture,14 cases were excellent and 7 cases were good.Conclusions:To treat the comminuted distal radial fractures that failed with closed reduction,open reduction and internal fixation with locking compression plate can achieve satisfied results.
Objective:To investigate the therapeutic efficiency of open reduction internal fixation with locking compression plate on comminuted distal radial fractures.Methods:Twenty-one cases of comminuted distal radial fractures that failed with closed reduction were treated with open reduction.internal fixation with locking compression plate.The healing of bone and long-term functional result were followed up.Results:All cases were followed up between 6-13 months.All the fractures were united and the the healing time was between 49-56 days.There were no complications such as infection,nonunion,breakage of the implants,or restriction of finger extension.According to the modified Green and O'Brien criteria of fracture,14 cases were excellent and 7 cases were good.Conclusions:To treat the comminuted distal radial fractures that failed with closed reduction,open reduction and internal fixation with locking compression plate can achieve satisfied results.
2010, 35(11): 1121-1122.
Abstract:
Objective:To compare the feasibility,safety and efficacy of hyperbaric ropivacaine in combined spinal epidural anesthesia (CSEA) for cesarean section.Methods:In a randomized double-blind investigation,sixty primiparas undergoing elective cesarean section delivery CSEA were enrolled.The parturients were randomly divided into:group R and group B,30 cases in each.The parturients in group R were administered with 0.75% ropivacaine 2 ml diluted with 10% glucose 1 ml;others in group B were administered with 0.75% bupivacaine 2 ml diluted with 10% glucose 1 ml.After spinal punctured at the L2~3 vertebral interspace,2.5-3.0 ml hyperbaric mixture was given intrathecally within 25 s,followed by insertion of an epidural catheter about 3.5 cm.Then patients were lay flat,turned on to the left lateral position about 15 degree.The sensory,motor block onset time,maximum sensory block level and motor block recovery times in the two groups were compared and thet wo anesthetic effects were evaluated.Results:In group R,the maximum block plane was lower than in group B,while the time of getting to the highest block levels after medicine injection was longer than in group B.The onset time of sensory and motor block in group R was significantly longer than in group B,but the duration time was shorter.In group R,the degree of low limbs motor nerves block assessed by modified Bromage Score was lower than in group B,whereas the motor block recovery time was shorter (P<0.05-P<0.01).There were no statistical differences in the sensony block recovery time Apgar scores and SpO2 of neonates between the two groups (P>0.05).Conclusions:The hyperbaric ropivacaine is an effective and safe drug in CSEA for cesarean section.
Objective:To compare the feasibility,safety and efficacy of hyperbaric ropivacaine in combined spinal epidural anesthesia (CSEA) for cesarean section.Methods:In a randomized double-blind investigation,sixty primiparas undergoing elective cesarean section delivery CSEA were enrolled.The parturients were randomly divided into:group R and group B,30 cases in each.The parturients in group R were administered with 0.75% ropivacaine 2 ml diluted with 10% glucose 1 ml;others in group B were administered with 0.75% bupivacaine 2 ml diluted with 10% glucose 1 ml.After spinal punctured at the L2~3 vertebral interspace,2.5-3.0 ml hyperbaric mixture was given intrathecally within 25 s,followed by insertion of an epidural catheter about 3.5 cm.Then patients were lay flat,turned on to the left lateral position about 15 degree.The sensory,motor block onset time,maximum sensory block level and motor block recovery times in the two groups were compared and thet wo anesthetic effects were evaluated.Results:In group R,the maximum block plane was lower than in group B,while the time of getting to the highest block levels after medicine injection was longer than in group B.The onset time of sensory and motor block in group R was significantly longer than in group B,but the duration time was shorter.In group R,the degree of low limbs motor nerves block assessed by modified Bromage Score was lower than in group B,whereas the motor block recovery time was shorter (P<0.05-P<0.01).There were no statistical differences in the sensony block recovery time Apgar scores and SpO2 of neonates between the two groups (P>0.05).Conclusions:The hyperbaric ropivacaine is an effective and safe drug in CSEA for cesarean section.
2010, 35(11): 1123-1125.
Abstract:
Objective:To evaluate the clinical application of plasmakinetic tissue management system (PK) in vaginal hysterectomy.Methods:The PK was used in vaginal hysterectomy in 98 patients (PK group) in our hospital.Another 78 patients which undergone the same operation with the traditional technique were belonged to traditional group.The minimally invasive effect was explored between these two groups.Results:In the PK group,the operation time was (38.59±8.87) min,the intraoperative blood loss was (40.12±17.19) ml;the postoperative pyrexia was 6 cases (5.81%) and granulation generation at the vaginal stump was 1 case (1.02%),which were significantly less than those in the traditional group (70.30±12.50) min, (123.50±38.12) ml,12 cases (14.81%) and 10 cases (12.80%) respectively (P<0.05 to P<0.01).The recovery of bowel movement was (18.05±5.65) h,the mean postoperative hospitalization was (5.72±1.42) d,which were shorten than those in the traditional group (22.45±7.43) h and (6.36±0.71) d,respectively (P<0.01).Conclusions:The PK simplified the procedure in vaginal hysterectomy,and it is a safe,effective and minimally invasive operation.It plays a great role to promote the vaginal gynecologic surgery in clinic.
Objective:To evaluate the clinical application of plasmakinetic tissue management system (PK) in vaginal hysterectomy.Methods:The PK was used in vaginal hysterectomy in 98 patients (PK group) in our hospital.Another 78 patients which undergone the same operation with the traditional technique were belonged to traditional group.The minimally invasive effect was explored between these two groups.Results:In the PK group,the operation time was (38.59±8.87) min,the intraoperative blood loss was (40.12±17.19) ml;the postoperative pyrexia was 6 cases (5.81%) and granulation generation at the vaginal stump was 1 case (1.02%),which were significantly less than those in the traditional group (70.30±12.50) min, (123.50±38.12) ml,12 cases (14.81%) and 10 cases (12.80%) respectively (P<0.05 to P<0.01).The recovery of bowel movement was (18.05±5.65) h,the mean postoperative hospitalization was (5.72±1.42) d,which were shorten than those in the traditional group (22.45±7.43) h and (6.36±0.71) d,respectively (P<0.01).Conclusions:The PK simplified the procedure in vaginal hysterectomy,and it is a safe,effective and minimally invasive operation.It plays a great role to promote the vaginal gynecologic surgery in clinic.
2010, 35(11): 1125-1126.
Abstract:
Objective:To investigate the clinical effect of total laparoscopic hysterectomy.Methods:Total laparoscopic hysterectomy were performed in patients with uterine myoma,adenomyosis and functional uterine bleeding.Results:All the 66 patients were operated successfully,one case was performed conversion to open laparotomy,complication occurred in one case.The success rate was 97%.The mean duration of surgery was 50-190 min,the mean bleeding quantity was 95-265 ml,duration of hospitalization ranged from 3 to 6 days.Conclusions:Total laparoscopic hysterectomy should be applied in clinical extensively,for its small trauma and low abdominal disturbance.
Objective:To investigate the clinical effect of total laparoscopic hysterectomy.Methods:Total laparoscopic hysterectomy were performed in patients with uterine myoma,adenomyosis and functional uterine bleeding.Results:All the 66 patients were operated successfully,one case was performed conversion to open laparotomy,complication occurred in one case.The success rate was 97%.The mean duration of surgery was 50-190 min,the mean bleeding quantity was 95-265 ml,duration of hospitalization ranged from 3 to 6 days.Conclusions:Total laparoscopic hysterectomy should be applied in clinical extensively,for its small trauma and low abdominal disturbance.
2010, 35(11): 1127-1128.
Abstract:
Objective:To explore the sodium new Houttuyfonate injection for the treatment of children autumn diarrhea.Methods:One hundred and sixty-three patients were divided into two groups,the control group and the sodium new Houttuyfonate injection treatment group.The control group used general treatment.Results:Compared with the control group (79.9%),the total effective rate of the sodium new Houttuyfonate injection treatment group (97.6%) was significantly higher (P<0.01),and fever time and ending time of diarrhea were significantly decreased (P<0.01).Conclusions:The effect of sodium new Houttuyfonate injection treatment on children autumn diarrhea was obvious,with less adverse reactions.
Objective:To explore the sodium new Houttuyfonate injection for the treatment of children autumn diarrhea.Methods:One hundred and sixty-three patients were divided into two groups,the control group and the sodium new Houttuyfonate injection treatment group.The control group used general treatment.Results:Compared with the control group (79.9%),the total effective rate of the sodium new Houttuyfonate injection treatment group (97.6%) was significantly higher (P<0.01),and fever time and ending time of diarrhea were significantly decreased (P<0.01).Conclusions:The effect of sodium new Houttuyfonate injection treatment on children autumn diarrhea was obvious,with less adverse reactions.
2010, 35(11): 1141-1143.
Abstract:
Objective:To analyze the relationship between the mRNA level of SmD1 antigen and the level of anti-SmD1 antibod in patients with systemic lupus erythematosws (SLE).Methods:The blood samples from 30 SLE patients with high level of anti-SmD1 antibody,30 cases with normal level of anti-SmD1 antibody and 30 normal controls were collected.The mRNA level of SmD1 antigen was detected by real-time PCR in all the cases.SPSS11.5 was used for statistical analysis.Results:In the SLE patients with high level of anti-SmD1 antibody,patients with normal level of anti-SmD1 antibody and the normal controls,-△△CT of real-time PCR was-0.60±2.99,-0.04±1.92 and-0.00±2.80,respectively.The difference was not significant (P>0.05).Conclusions:The gene expression level of SmD1 has no significant different among the three groups.The immune abnormity in the cases with SLE is almost involved in the whole immune system.It is impossible to explain the disorder of immune system by the abnormity of mRNA level of SmD1 antigen.
Objective:To analyze the relationship between the mRNA level of SmD1 antigen and the level of anti-SmD1 antibod in patients with systemic lupus erythematosws (SLE).Methods:The blood samples from 30 SLE patients with high level of anti-SmD1 antibody,30 cases with normal level of anti-SmD1 antibody and 30 normal controls were collected.The mRNA level of SmD1 antigen was detected by real-time PCR in all the cases.SPSS11.5 was used for statistical analysis.Results:In the SLE patients with high level of anti-SmD1 antibody,patients with normal level of anti-SmD1 antibody and the normal controls,-△△CT of real-time PCR was-0.60±2.99,-0.04±1.92 and-0.00±2.80,respectively.The difference was not significant (P>0.05).Conclusions:The gene expression level of SmD1 has no significant different among the three groups.The immune abnormity in the cases with SLE is almost involved in the whole immune system.It is impossible to explain the disorder of immune system by the abnormity of mRNA level of SmD1 antigen.
Compar asion of the test results of partial biochemical parameters by two types of chemical analyzer
2010, 35(11): 1143-1144.
Abstract:
Objective:To compare the test results of partial biochemical items verified by VITROS 250 dry chemical analyzer and HITACHI 7600-200 automatic biochemistry instrument.Methods:The parameters including ALT,AST,ALP,GGT,TP,ALB,TBIL and DBIL in fifty samples were analyzed and recorded with these two instruments.Results:There was no statistical significance of the results of AST,GGT,TP and TBIL detected by these two analytical methods (P>0.05),and these results had preferable correlation.While there was statistical differences between the results of ALT,ALP,ALB and DBIL with these two analytical methods (P<0.05).Conclusions:If there are two or more biochemical analyzers to detect the same testing items,it is necessary to compare and calibrate the different testing results regularly to insure the accuracy of testing results.
Objective:To compare the test results of partial biochemical items verified by VITROS 250 dry chemical analyzer and HITACHI 7600-200 automatic biochemistry instrument.Methods:The parameters including ALT,AST,ALP,GGT,TP,ALB,TBIL and DBIL in fifty samples were analyzed and recorded with these two instruments.Results:There was no statistical significance of the results of AST,GGT,TP and TBIL detected by these two analytical methods (P>0.05),and these results had preferable correlation.While there was statistical differences between the results of ALT,ALP,ALB and DBIL with these two analytical methods (P<0.05).Conclusions:If there are two or more biochemical analyzers to detect the same testing items,it is necessary to compare and calibrate the different testing results regularly to insure the accuracy of testing results.
2010, 35(11): 1148-1150.
Abstract:
Objective:To study the correlation between psychosomatic sub-health symptoms and internet addiction disorders (IAD) among middle school students.Methods:Based on stratified,random cluster sampling,a questionnaire investigation was conducted among 2 910 students from 6 middle schools of Bengbu city,including demographic characteristics,multidimensional sub-health questionnaire of adolescents (MSQA) and Young internet addiction scale.Results:The prevalence of physical,psychical and psychosomatic sub-healthy symptoms of the middle school student was 13.6%,55.4% and 64.0% respectively,and the three types of sub-health symptoms increased with the ascending of grades.The prevalence of IAD among middle school students was 9.3%.Boys had a higher prevalence (11.2%) than girls (6.9%),and urban students (10.7%) had a higher prevalence than the rural ones (6.8%) (P<0.01).The prevalence of physical,psychical and psychosomatic sub-healthy symptoms in students with IAD was higher than that with no IAD or not using internet (P<0.01).Conclusions:Internet addition disorder contributes to the arising of sub-healthy symptoms in middle school students.
Objective:To study the correlation between psychosomatic sub-health symptoms and internet addiction disorders (IAD) among middle school students.Methods:Based on stratified,random cluster sampling,a questionnaire investigation was conducted among 2 910 students from 6 middle schools of Bengbu city,including demographic characteristics,multidimensional sub-health questionnaire of adolescents (MSQA) and Young internet addiction scale.Results:The prevalence of physical,psychical and psychosomatic sub-healthy symptoms of the middle school student was 13.6%,55.4% and 64.0% respectively,and the three types of sub-health symptoms increased with the ascending of grades.The prevalence of IAD among middle school students was 9.3%.Boys had a higher prevalence (11.2%) than girls (6.9%),and urban students (10.7%) had a higher prevalence than the rural ones (6.8%) (P<0.01).The prevalence of physical,psychical and psychosomatic sub-healthy symptoms in students with IAD was higher than that with no IAD or not using internet (P<0.01).Conclusions:Internet addition disorder contributes to the arising of sub-healthy symptoms in middle school students.
2010, 35(11): 1151-1153.
Abstract:
Objective:To analyze the current status of hospital infection management in community health service stations and propose improvement measures.Methods:According to the Ministry of Health hospital infection management documents,laws,regulations and the relevant contents in "The assessment of Standardization of community healthy service center in Anhui Province",twenty-seven community health service centers in Suzhou city were investigated about the status of hospital infection.Results:The investigation results showed that in community health service stations,the hospital infection control regulations were not perfected,sterilization management was not standardized,disposal of medical waste categories was not standardized,the occupational safety and protection were not in place,and the knowledge of hospital infection problems was lack.Conclusions:Emphasizing hospital infection management,establishing and improving infection management organization,strengthening to train staff in community health service centers about the medical knowledge of how to control hospital infection are the key factors to improve management of hospital infection in community health service stations.
Objective:To analyze the current status of hospital infection management in community health service stations and propose improvement measures.Methods:According to the Ministry of Health hospital infection management documents,laws,regulations and the relevant contents in "The assessment of Standardization of community healthy service center in Anhui Province",twenty-seven community health service centers in Suzhou city were investigated about the status of hospital infection.Results:The investigation results showed that in community health service stations,the hospital infection control regulations were not perfected,sterilization management was not standardized,disposal of medical waste categories was not standardized,the occupational safety and protection were not in place,and the knowledge of hospital infection problems was lack.Conclusions:Emphasizing hospital infection management,establishing and improving infection management organization,strengthening to train staff in community health service centers about the medical knowledge of how to control hospital infection are the key factors to improve management of hospital infection in community health service stations.
2010, 35(11): 1154-1155.
Abstract:
Objective:To evaluate the bronchial arterial embolization (BAE) in treatment of massive hemoptysis.Methods:Twenty-one cases of massive hemoptysis received embolization therapy using gelfoam and polyvinyl alcohol micropheres,and all were followed up for one month to three years.Results:The therapy reached satisfactory results in all the 21 patients.Instant effects were observed in 16 patients and 5 patients had a decreased bleeding compared with pre-therapy.Recurrent hemoptysis was observed in only 2 cases in the follow-up.Conclusions:BAE is safe and effective in treatment of massive hemoptysis.
Objective:To evaluate the bronchial arterial embolization (BAE) in treatment of massive hemoptysis.Methods:Twenty-one cases of massive hemoptysis received embolization therapy using gelfoam and polyvinyl alcohol micropheres,and all were followed up for one month to three years.Results:The therapy reached satisfactory results in all the 21 patients.Instant effects were observed in 16 patients and 5 patients had a decreased bleeding compared with pre-therapy.Recurrent hemoptysis was observed in only 2 cases in the follow-up.Conclusions:BAE is safe and effective in treatment of massive hemoptysis.
2010, 35(11): 1159-1161.
Abstract:
Objective:To explore an effective method to improve the teaching quality of preventive medicine experimental classes.Methods:A series of reforms such as breaking the boundaries between different subjects,merging experimental plans,renewing teaching materials and reforming experimental teaching method were carried out.Results:The students' study interest was effectively aroused and their ability of applying theories to practice was significantly elevated.Conclusions:The reforms taken may greatly enhance the students' mastery of their professional knowledge of preventive medicine,thus elevating their ability of systemizing and making use of their learning.
Objective:To explore an effective method to improve the teaching quality of preventive medicine experimental classes.Methods:A series of reforms such as breaking the boundaries between different subjects,merging experimental plans,renewing teaching materials and reforming experimental teaching method were carried out.Results:The students' study interest was effectively aroused and their ability of applying theories to practice was significantly elevated.Conclusions:The reforms taken may greatly enhance the students' mastery of their professional knowledge of preventive medicine,thus elevating their ability of systemizing and making use of their learning.
2010, 35(11): 1170-1172.
Abstract:
Objective:To evaluate the anxiety and depression status in spouses of patients with breast cancer,and analyze the related factors.Methods:The self-designed questionnaire including self-rating anxiety scale (SAS),self-rating depression scale (SDS),and sociology of population data was used to investigate 110 spouses of breast cancer patients.Results:The incidence of anxiety and depression in patients with breast cancer was 43.36% and 40.9.1% respectively.There was a significant difference comparing with the norm of china (P<0.01).The related factors included age,educational level,pay forms,the monthly income of family and tumor stages and so on.Conclusions:The anxiety and depression incidence in spouse of patients with breast cancer is relatively higher.Psychological intervention to spouse should be strengthened in the perioperative period of patients with breast cancer.
Objective:To evaluate the anxiety and depression status in spouses of patients with breast cancer,and analyze the related factors.Methods:The self-designed questionnaire including self-rating anxiety scale (SAS),self-rating depression scale (SDS),and sociology of population data was used to investigate 110 spouses of breast cancer patients.Results:The incidence of anxiety and depression in patients with breast cancer was 43.36% and 40.9.1% respectively.There was a significant difference comparing with the norm of china (P<0.01).The related factors included age,educational level,pay forms,the monthly income of family and tumor stages and so on.Conclusions:The anxiety and depression incidence in spouse of patients with breast cancer is relatively higher.Psychological intervention to spouse should be strengthened in the perioperative period of patients with breast cancer.
2010, 35(11): 1173-1174.
Abstract:
Objective:To investigate the effect of orally taking Hengkangzhengqing on bowel preparation of patients before undergoing colonoscope examination.Methods:A total of 128 patients needed to carry out colonoscope were selected and divided into Hengkangzhengqing group and mannitol group randomly.The data were collected by questionnaire and observation methods.Then the scores of bowel preparation for colonoscope of the two groups were ranked and compared with each other.Results:The total effective rate of bowel cleaning with Hengkangzhengqing was 95.6%,which was higher than in mannitol group 85.0% (P<0.05).Conclusions:The effect of orally taking Hengkangzhengqing on bowel preparation is remarkable for patients.It has lower incidence of adverse reactions and is easy to manipulate.It is a good method for bowel preparation for patient s before colonoscope examination.
Objective:To investigate the effect of orally taking Hengkangzhengqing on bowel preparation of patients before undergoing colonoscope examination.Methods:A total of 128 patients needed to carry out colonoscope were selected and divided into Hengkangzhengqing group and mannitol group randomly.The data were collected by questionnaire and observation methods.Then the scores of bowel preparation for colonoscope of the two groups were ranked and compared with each other.Results:The total effective rate of bowel cleaning with Hengkangzhengqing was 95.6%,which was higher than in mannitol group 85.0% (P<0.05).Conclusions:The effect of orally taking Hengkangzhengqing on bowel preparation is remarkable for patients.It has lower incidence of adverse reactions and is easy to manipulate.It is a good method for bowel preparation for patient s before colonoscope examination.
2010, 35(11): 1175-1177.
Abstract:
Objective:To analyze the application of a new safe adult musculus vastus lateral injection (proportion method).Methods:Two hundred patients were divided into the traditional treatment group and the proportion treatment group according to the musculus vastus lateral injection provided by literature.The application safety zone and side effect were analyzed contrastively.Results:The irritative musculus vastus lateral inferior neuroligic symptom was present of the 8 cases of traditional treatment group,while the neurological symptoms of vascular injury was not confirmed in proportion treatment group.It was more difficult to determine the safety zone in the traditional treatment group,especially which in the female patients was significantly smaller.The traditional treatment group in which appearred sclerosis and pain impacting the movement was significantly higher than the proportion treament group (P<0.01),however there were not abscesses and other serious infectious complications in both groups.There were no apparent contracture of muscle necrosis in the traditional treatment group and the proportion treatment group.Conclusions:The best safety zone (abducting legs,between above 2/5 and the below 1/5 in the lateral thigh region) of the proportion method group is accurate and easily mastered.In the safe zone (abducting legs,lateral thigh below 3/5 regions),increasing 1.0-1.2 cm of the injection depth of the skin and superficial fascia thickness is safe.The proportion method can reduce the induration,pain and infection complications.
Objective:To analyze the application of a new safe adult musculus vastus lateral injection (proportion method).Methods:Two hundred patients were divided into the traditional treatment group and the proportion treatment group according to the musculus vastus lateral injection provided by literature.The application safety zone and side effect were analyzed contrastively.Results:The irritative musculus vastus lateral inferior neuroligic symptom was present of the 8 cases of traditional treatment group,while the neurological symptoms of vascular injury was not confirmed in proportion treatment group.It was more difficult to determine the safety zone in the traditional treatment group,especially which in the female patients was significantly smaller.The traditional treatment group in which appearred sclerosis and pain impacting the movement was significantly higher than the proportion treament group (P<0.01),however there were not abscesses and other serious infectious complications in both groups.There were no apparent contracture of muscle necrosis in the traditional treatment group and the proportion treatment group.Conclusions:The best safety zone (abducting legs,between above 2/5 and the below 1/5 in the lateral thigh region) of the proportion method group is accurate and easily mastered.In the safe zone (abducting legs,lateral thigh below 3/5 regions),increasing 1.0-1.2 cm of the injection depth of the skin and superficial fascia thickness is safe.The proportion method can reduce the induration,pain and infection complications.
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