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2010 Vol. 35, No. 7
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2010, 35(7): 649-652.
Abstract:
Objective: To investigate whether the activation of mitochondrial calcium activated potassium channel (mitoKCa) can potentiate the cardioplegic solution of modified St.Thomas cardioplegia in isolated rat hearts subjected to ischemia and reperfusion.Methods: The isolated perfused rat hearts were subjected to 30 min global ischemia and 120 min reperfusion.The rats were divided into four groups:ischemia and reperfusion group;modified St.Thomas cardioplegia group;modified St.Thomas cardioplegia+NS1619 group and modified St.Thomas cardioplegia+NS1619+Paxilline group.The ventricular hemodynamic parameters,lactate dehydrogenase (LDH) release from coronary flow during reperfusion and myocardial water content were measured.Results: In contrast to ischemia and reperfusion group,modified St.Thomas cardioplegia decreased the elevation of left ventricular end-diastolic pressure (P<0.01),increased rate-pressure product (P<0.01) and coronary flow (P<0.05),reduced LDH release (P<0.01) and mycardical water content (P<0.01).Administration of NS1619,an activator of mitoKCa channel potentiated the role of modified St.Thomas cardioplegia,LDH release and mycardical water content further decreased (P<0.01),and the improvement of left ventricular performance was more significant (P<0.01).The inhibitor of mitoKCa channel Paxilline abolished the role of NS 1619 (P<0.05-P<0.01).Conclusions: These findings indicate that activation of mitochondrial calcium activated potassium channel can potentiate the cardioplegic solution of cardioplegia.
Objective: To investigate whether the activation of mitochondrial calcium activated potassium channel (mitoKCa) can potentiate the cardioplegic solution of modified St.Thomas cardioplegia in isolated rat hearts subjected to ischemia and reperfusion.Methods: The isolated perfused rat hearts were subjected to 30 min global ischemia and 120 min reperfusion.The rats were divided into four groups:ischemia and reperfusion group;modified St.Thomas cardioplegia group;modified St.Thomas cardioplegia+NS1619 group and modified St.Thomas cardioplegia+NS1619+Paxilline group.The ventricular hemodynamic parameters,lactate dehydrogenase (LDH) release from coronary flow during reperfusion and myocardial water content were measured.Results: In contrast to ischemia and reperfusion group,modified St.Thomas cardioplegia decreased the elevation of left ventricular end-diastolic pressure (P<0.01),increased rate-pressure product (P<0.01) and coronary flow (P<0.05),reduced LDH release (P<0.01) and mycardical water content (P<0.01).Administration of NS1619,an activator of mitoKCa channel potentiated the role of modified St.Thomas cardioplegia,LDH release and mycardical water content further decreased (P<0.01),and the improvement of left ventricular performance was more significant (P<0.01).The inhibitor of mitoKCa channel Paxilline abolished the role of NS 1619 (P<0.05-P<0.01).Conclusions: These findings indicate that activation of mitochondrial calcium activated potassium channel can potentiate the cardioplegic solution of cardioplegia.
2010, 35(7): 652-655.
Abstract:
Objective: To study whether Staphylococcus aureus (SA) could invade the cultured human osteoblasts and to investigate whether different infective dose and time affect the number of intracellular bacteria.Methods: Transmission electron microscope (TEM) was used to observe the invasion of SA and the number of cells containing intracellular SA;And the mean fluorescence units of total cells were detected by flow cytometry.Results: TEM showed that SA could penetrate the human ostaoblasts.With the infective dose increasing,the number of intracellular bacteria also grew up,which reached the top at 4 h;The number of intracellular bacteria had no difference at 1 h and 2 h (P>0.05),but the difference was significant at other time points (P<0.01).Conclusions: The results suggest that SA can penetrate the human osteoblasts,and the number of intracellular bacteria is associated with the infective dose and time.
Objective: To study whether Staphylococcus aureus (SA) could invade the cultured human osteoblasts and to investigate whether different infective dose and time affect the number of intracellular bacteria.Methods: Transmission electron microscope (TEM) was used to observe the invasion of SA and the number of cells containing intracellular SA;And the mean fluorescence units of total cells were detected by flow cytometry.Results: TEM showed that SA could penetrate the human ostaoblasts.With the infective dose increasing,the number of intracellular bacteria also grew up,which reached the top at 4 h;The number of intracellular bacteria had no difference at 1 h and 2 h (P>0.05),but the difference was significant at other time points (P<0.01).Conclusions: The results suggest that SA can penetrate the human osteoblasts,and the number of intracellular bacteria is associated with the infective dose and time.
2010, 35(7): 656-659.
Abstract:
Objective: To detect the mRNA expression of brain and acute leukemia,cytoplasmic (BAALC) in perpheral blood mononuclear cells (PBMC),BAALC of patients with acute myeloid leukemia (AML) by comparative real-time reverse transcriptase-polymerase chain reaction (RQ-PCR) with SYBR Green.Methods: PBMC was obtained from 12 patients with AML and 5 healthy donors,from which total RNA was extracted and reverse transcribed into cDNA.The leukemia cell lines K562 cells was selected as positive control.The expression of BAALC was detected by RQ-PCR with SYBR Green assay.Results: The BAALC mRNA could not be detected in PBMC of healthy donors.However,in 12 patients with AML,it was highly expressed in 8 of them.The relative values were 0.8-5.6 compared with K562 cells.Conclusions: The expression of BAALC in PBMC of patients with AML could be detected by SYBR Green comparative RQ-PCR.It was a steady,sensitive and reliable assay method.
Objective: To detect the mRNA expression of brain and acute leukemia,cytoplasmic (BAALC) in perpheral blood mononuclear cells (PBMC),BAALC of patients with acute myeloid leukemia (AML) by comparative real-time reverse transcriptase-polymerase chain reaction (RQ-PCR) with SYBR Green.Methods: PBMC was obtained from 12 patients with AML and 5 healthy donors,from which total RNA was extracted and reverse transcribed into cDNA.The leukemia cell lines K562 cells was selected as positive control.The expression of BAALC was detected by RQ-PCR with SYBR Green assay.Results: The BAALC mRNA could not be detected in PBMC of healthy donors.However,in 12 patients with AML,it was highly expressed in 8 of them.The relative values were 0.8-5.6 compared with K562 cells.Conclusions: The expression of BAALC in PBMC of patients with AML could be detected by SYBR Green comparative RQ-PCR.It was a steady,sensitive and reliable assay method.
2010, 35(7): 659-662.
Abstract:
Objective: To investigate the effect of 5-Aza-2'-deoxycytidine (5-Aza-CdR) on human leukocyte antigen C (HLA-C) expression and the relationship with DNA methyltransferase 1 (DNMT1) in gastric cancer cells.Methods: The gastric cancer cells BCG823 cultured in medium containing 10 μmol/L 5-Aza-CdR (final concentration) were as experiment group.The untreated gastric cancer cell were as control group.The transcripts of HLA-C and DNMT1 genes were detected by semi-quantitative reverse transcription-PCR (RT-PCR).The methylation level of HLA-C was analyzed by methylation-specific PCR (MSP).Results: The expression of DNMT1 mRNA in BGC823 cells treated with 5-Aza-CdR were obvious less than in untreated cells.The DNA hypermethylation in CpG island of HLA-C gene was reversed and leaded to up-regulation of HLA-C transcripts.There was the statistical significance between the control and experiment group in the expression of HLA-C mRNA analyzed by Gel-Pro Analyzer (P<0.01).Conclusions: 5-Aza-CdR treatment can lead to DNA demethylation of HLA-C through inhibiting the expression of DNMT1,and then up-regulating the expression of HLA-C mRNA.
Objective: To investigate the effect of 5-Aza-2'-deoxycytidine (5-Aza-CdR) on human leukocyte antigen C (HLA-C) expression and the relationship with DNA methyltransferase 1 (DNMT1) in gastric cancer cells.Methods: The gastric cancer cells BCG823 cultured in medium containing 10 μmol/L 5-Aza-CdR (final concentration) were as experiment group.The untreated gastric cancer cell were as control group.The transcripts of HLA-C and DNMT1 genes were detected by semi-quantitative reverse transcription-PCR (RT-PCR).The methylation level of HLA-C was analyzed by methylation-specific PCR (MSP).Results: The expression of DNMT1 mRNA in BGC823 cells treated with 5-Aza-CdR were obvious less than in untreated cells.The DNA hypermethylation in CpG island of HLA-C gene was reversed and leaded to up-regulation of HLA-C transcripts.There was the statistical significance between the control and experiment group in the expression of HLA-C mRNA analyzed by Gel-Pro Analyzer (P<0.01).Conclusions: 5-Aza-CdR treatment can lead to DNA demethylation of HLA-C through inhibiting the expression of DNMT1,and then up-regulating the expression of HLA-C mRNA.
2010, 35(7): 662-664.
Abstract:
Objective: To study the apoptosis of K562 cells induced by Andi injection (Adi).Methods: Flow cytometer was used to detect the apoptosis of K562 cells after the action of Adi,and the morphological changes were observed by fluorescence microscopy and electron microscopy.The effects of Adi on the proliferation and apoptosis of K562 cells were evaluated.Results: The apoptosis rates were 50% and 39% in the cells that had been treated with 10 and 20 μg/ml Adi,respectively,which was significantly higher than the 10% in the control group (P<0.05);Abnormal morphological changes of K562 cells were observed in Adi group by fluorescence microscopy and electron microscopy.Conclusions: Adi can obviously inhibit the proliferation of anti-leukemic cells and induce the apoptosis of K562 cells.
Objective: To study the apoptosis of K562 cells induced by Andi injection (Adi).Methods: Flow cytometer was used to detect the apoptosis of K562 cells after the action of Adi,and the morphological changes were observed by fluorescence microscopy and electron microscopy.The effects of Adi on the proliferation and apoptosis of K562 cells were evaluated.Results: The apoptosis rates were 50% and 39% in the cells that had been treated with 10 and 20 μg/ml Adi,respectively,which was significantly higher than the 10% in the control group (P<0.05);Abnormal morphological changes of K562 cells were observed in Adi group by fluorescence microscopy and electron microscopy.Conclusions: Adi can obviously inhibit the proliferation of anti-leukemic cells and induce the apoptosis of K562 cells.
2010, 35(7): 665-667.
Abstract:
Objective: To study the association of hepatitis B virus (HBV)X gene and its mutation with hepatocellular carcinogenesis (HCC).Methods: HBV X gene in the liver tissues of 22 HCC patients whose hepatitis B surface antigen (HBsAg)was positive and 15 chronic asymptomatic carriers (CAC)patients were detected wih polymerase chain reaction (PCR);the PCR product was sequenced and analyzed;5 normal liver tissues with negative HBsAg acted as control.Results: The detection rate of HBV X gene in the carcinoma tissues of 22 HCC patients and 15 CAC patients was 68.18% and 46.67%,respectively.HBV X gene was not detected in the 5 normal liver tissues.The difference was significant between them (P<0.05).The detection rate of HBV X gene in carcinoma tissues and CAC liver tissues had no statistical difference (P>0.05).The double mutation rate of 1 762T/1 764A in carcinoma tissues and CAC liver tissues was 93.33% and 2/7,respectively.And the former was higher than the latter (P=0.004 3).There was no detection of mutation of 1 762T or 1 764A alone.Conclusions: There is a high detection rate of HBV X gene and a high double mutation rate of 1762T/1764A in the carcinoma tissues of HCC patients.HBV X gene and double mutations may play an important role in the carcinogenesis of HCC.
Objective: To study the association of hepatitis B virus (HBV)X gene and its mutation with hepatocellular carcinogenesis (HCC).Methods: HBV X gene in the liver tissues of 22 HCC patients whose hepatitis B surface antigen (HBsAg)was positive and 15 chronic asymptomatic carriers (CAC)patients were detected wih polymerase chain reaction (PCR);the PCR product was sequenced and analyzed;5 normal liver tissues with negative HBsAg acted as control.Results: The detection rate of HBV X gene in the carcinoma tissues of 22 HCC patients and 15 CAC patients was 68.18% and 46.67%,respectively.HBV X gene was not detected in the 5 normal liver tissues.The difference was significant between them (P<0.05).The detection rate of HBV X gene in carcinoma tissues and CAC liver tissues had no statistical difference (P>0.05).The double mutation rate of 1 762T/1 764A in carcinoma tissues and CAC liver tissues was 93.33% and 2/7,respectively.And the former was higher than the latter (P=0.004 3).There was no detection of mutation of 1 762T or 1 764A alone.Conclusions: There is a high detection rate of HBV X gene and a high double mutation rate of 1762T/1764A in the carcinoma tissues of HCC patients.HBV X gene and double mutations may play an important role in the carcinogenesis of HCC.
2010, 35(7): 668-671.
Abstract:
Objective: To evaluate the therapeutic effects and factors affecting the patients' survival of two different radiotherapies in the treatment of brain metastases of non-small-cell lung carcinoma (NSCLC).Methods: In the fifty-four cases of brain metastases of NSCLC receiving radiotherapy,37 cases were treated with three-dimensional conformal radiotherapy (3D-CRT) and whde brain radiotherapy (WBR),while the other 17 underwent 3D-CRT alone.Kaplan-Meier method was used to analyze the survival rate and local control rate,and Cox proportional hazards model was applied for determining the prognostic factors influencing the patients' survival.Results: The median survival was 9 months for the patients who received 3D-CRT and WBR,The median survival was 7 monthes for the patients who simply received 3D-CRT.Statistics detected no significant difference between the two groups (P>0.05).Multivariate analysis showed that the recursive portioning analysis (RPA) and metastasis numbers were the independent prognostic factors for the patients'survival.Conclusions: WBR combined with 3D-CRT did not benefit the patients with brain metastases of NSCLC for their survival.RPA and metastasis numbers were the independent prognostic factors for the patients'survival.
Objective: To evaluate the therapeutic effects and factors affecting the patients' survival of two different radiotherapies in the treatment of brain metastases of non-small-cell lung carcinoma (NSCLC).Methods: In the fifty-four cases of brain metastases of NSCLC receiving radiotherapy,37 cases were treated with three-dimensional conformal radiotherapy (3D-CRT) and whde brain radiotherapy (WBR),while the other 17 underwent 3D-CRT alone.Kaplan-Meier method was used to analyze the survival rate and local control rate,and Cox proportional hazards model was applied for determining the prognostic factors influencing the patients' survival.Results: The median survival was 9 months for the patients who received 3D-CRT and WBR,The median survival was 7 monthes for the patients who simply received 3D-CRT.Statistics detected no significant difference between the two groups (P>0.05).Multivariate analysis showed that the recursive portioning analysis (RPA) and metastasis numbers were the independent prognostic factors for the patients'survival.Conclusions: WBR combined with 3D-CRT did not benefit the patients with brain metastases of NSCLC for their survival.RPA and metastasis numbers were the independent prognostic factors for the patients'survival.
2010, 35(7): 671-673.
Abstract:
Objective: To investigate the role of Shenfu Zhusheye in preventing the side effects of interferon-alpha on the white blood cell,red blood cell and blood platelet in chronic hepatitis B patients.Methods: A total of 68 chronic hepatitis B patients with interferon-alpha-related myelosuppression were randomly divided into study group and control group.The control group (34 cases) received combination therapy of leucogen and batilol tablets.The study group (34 cases) received Shenfu Zhusheye intravenous injection.The white blood cell count,neutrophil count and the blood platelet count were measured weekly in both groups.Results: The levels of the plasma blood cell count and neutrophil count in the study group were significantly lower than those in control group (P>0.05).The scores of debility and agrypnia in the study group were lower than those in the control group (P<0.01).Conclusions: Shenfu Zhusheye therapy is effective in preventing interferon-alpha-related myelosuppression in chronic hepatitis B patients.
Objective: To investigate the role of Shenfu Zhusheye in preventing the side effects of interferon-alpha on the white blood cell,red blood cell and blood platelet in chronic hepatitis B patients.Methods: A total of 68 chronic hepatitis B patients with interferon-alpha-related myelosuppression were randomly divided into study group and control group.The control group (34 cases) received combination therapy of leucogen and batilol tablets.The study group (34 cases) received Shenfu Zhusheye intravenous injection.The white blood cell count,neutrophil count and the blood platelet count were measured weekly in both groups.Results: The levels of the plasma blood cell count and neutrophil count in the study group were significantly lower than those in control group (P>0.05).The scores of debility and agrypnia in the study group were lower than those in the control group (P<0.01).Conclusions: Shenfu Zhusheye therapy is effective in preventing interferon-alpha-related myelosuppression in chronic hepatitis B patients.
2010, 35(7): 674-676.
Abstract:
Objective: To explore the appropriate operative/re-operative methods and evaluate the outcomes of severe hepatic trauma.Methods: Among the 23 patients suffered from severe hepatic trauma,two patients accepted suture repair after debridement,9 patients accepted plugging repair by great omentum,8 by hepatectomy (one also treated with ribbon gauze plugging around the liver),and the other four accepted ribbon gauze plugging around the liver (two of the patients underwent secondary hepatectomy).Splenectomy was carried out for 3 patients and gastrorrhaphy was carried out for 1 patient.Results: Among the 23 patients,the hepatic trauma was graded as Ⅲ for 13 cases,Ⅳ for 8 cases,and Ⅴ for 2 cases,respectively.Twenty one patients were cured without accompanying with any complications.Two patients died.Conclusions: Operation is an effective treatment for severe hepatic trauma.The choice of operative method depends on the situation of the patient.If the surgery condition is appropriate,the hepatectomy could be the best choice for severe hepatic trauma due to the efficacy and minimum complications.
Objective: To explore the appropriate operative/re-operative methods and evaluate the outcomes of severe hepatic trauma.Methods: Among the 23 patients suffered from severe hepatic trauma,two patients accepted suture repair after debridement,9 patients accepted plugging repair by great omentum,8 by hepatectomy (one also treated with ribbon gauze plugging around the liver),and the other four accepted ribbon gauze plugging around the liver (two of the patients underwent secondary hepatectomy).Splenectomy was carried out for 3 patients and gastrorrhaphy was carried out for 1 patient.Results: Among the 23 patients,the hepatic trauma was graded as Ⅲ for 13 cases,Ⅳ for 8 cases,and Ⅴ for 2 cases,respectively.Twenty one patients were cured without accompanying with any complications.Two patients died.Conclusions: Operation is an effective treatment for severe hepatic trauma.The choice of operative method depends on the situation of the patient.If the surgery condition is appropriate,the hepatectomy could be the best choice for severe hepatic trauma due to the efficacy and minimum complications.
2010, 35(7): 676-677.
Abstract:
Objective: To investigate the causes and diagnostic treatment of pseudomyxadenoma in peritoneal cavity.Methods: Four cases of pseudomyxadenoma in peritoneal cavity were analyzed retrospectively.Two cases underwent complete tumor resection,and the others underwent cytoreductive surgery.Results: One case was found with myxadenoma secondary to post-appendicectomy,the other three cases with pseudomyxadenoma peritonei secondary to the rupture of ovarian myxadenoma.Two cases died of bowel obstruction and the whole body failure in half a year after operation because of extensive implantation in peritoneal cavity.The other two cases survived well under the treatment of peritoneal chemotherapy.Conclusions: Peritoneal pseudomyxadenoma is a secondary malignant tumor with low degree.It presents in redistribution phenomenon.Prevention is a key point.The suitable treatment is to receive combined therapy,which operation is dominant.
Objective: To investigate the causes and diagnostic treatment of pseudomyxadenoma in peritoneal cavity.Methods: Four cases of pseudomyxadenoma in peritoneal cavity were analyzed retrospectively.Two cases underwent complete tumor resection,and the others underwent cytoreductive surgery.Results: One case was found with myxadenoma secondary to post-appendicectomy,the other three cases with pseudomyxadenoma peritonei secondary to the rupture of ovarian myxadenoma.Two cases died of bowel obstruction and the whole body failure in half a year after operation because of extensive implantation in peritoneal cavity.The other two cases survived well under the treatment of peritoneal chemotherapy.Conclusions: Peritoneal pseudomyxadenoma is a secondary malignant tumor with low degree.It presents in redistribution phenomenon.Prevention is a key point.The suitable treatment is to receive combined therapy,which operation is dominant.
2010, 35(7): 678-681.
Abstract:
Objective: To investigate the expression of FEZ1/LZTS1 mRNA and evaluate its effects on the tumorigenesis and progression in bladder transitional cell carcinomas (BTCCs).Methods: The expression of FEZ1/LZTS1 mRNA in 40 BTCCs and 10 normal bladder mucosas was detected by RT-PCR.Results: The negative expression of FEZ1/LZTS1 mRNA in BTCC (57.50%) was significantly higher than that in normal bladder mucosa (P<0.01).Statistical analysis showed a significant association between the Absence of FEZ1/LZTS1 mRNA and the histological grade of BTCC.The negative expression of FEZ1/LZTS1 mRNA was 28.57%,61.54% and 84.62% in gradeⅠ,gradeⅡ and grade Ⅲ BTCC,respectively (P<0.05).The negative expression was 28.57% and 89.47% in Ta-T1 BTCC and T2-T4 BTCC,respectively (P<0.01).Conclusions: The Absence of FEZ1/LZTS1 mRNA expression in BTCC is up-regulated and associated with the histological grade and the clinical stages of BTCC.The Absence of FEZ1/LZTS1 expression might act as a reference indicator in evaluating the differentiation of the tumor and predicting the prognosis.
Objective: To investigate the expression of FEZ1/LZTS1 mRNA and evaluate its effects on the tumorigenesis and progression in bladder transitional cell carcinomas (BTCCs).Methods: The expression of FEZ1/LZTS1 mRNA in 40 BTCCs and 10 normal bladder mucosas was detected by RT-PCR.Results: The negative expression of FEZ1/LZTS1 mRNA in BTCC (57.50%) was significantly higher than that in normal bladder mucosa (P<0.01).Statistical analysis showed a significant association between the Absence of FEZ1/LZTS1 mRNA and the histological grade of BTCC.The negative expression of FEZ1/LZTS1 mRNA was 28.57%,61.54% and 84.62% in gradeⅠ,gradeⅡ and grade Ⅲ BTCC,respectively (P<0.05).The negative expression was 28.57% and 89.47% in Ta-T1 BTCC and T2-T4 BTCC,respectively (P<0.01).Conclusions: The Absence of FEZ1/LZTS1 mRNA expression in BTCC is up-regulated and associated with the histological grade and the clinical stages of BTCC.The Absence of FEZ1/LZTS1 expression might act as a reference indicator in evaluating the differentiation of the tumor and predicting the prognosis.
2010, 35(7): 681-683.
Abstract:
Objective: To study the etiology,clinical type and neural anatomy of alien hand syndrome (AHS).Methods: Two cases of alien hand syndrome were analyzed combined with review retrospectively.Results: Both of the 2 patients had the alieness of the affected extremity,motor preservation,autocriticism,the mirror movement and other symptoms.CT and MRI showed lesions mainly involving the corpus callosum.Symptoms of the two cases were improved after symptomatic treatment.Conclusions: Alien hand syndrome has complex causes,diverse symptoms.A common clinical classification includes the frontal lobe form,corpus callosum form and posterior form.Lesions involved the medial frontal cortex,corpus callosum,parietal lobe,thalamus,etc.The patients with AHS should be given active imaging examination,specific analysis of its causes,and timely treatment to prevent misdiagnosis and delayed treatment.
Objective: To study the etiology,clinical type and neural anatomy of alien hand syndrome (AHS).Methods: Two cases of alien hand syndrome were analyzed combined with review retrospectively.Results: Both of the 2 patients had the alieness of the affected extremity,motor preservation,autocriticism,the mirror movement and other symptoms.CT and MRI showed lesions mainly involving the corpus callosum.Symptoms of the two cases were improved after symptomatic treatment.Conclusions: Alien hand syndrome has complex causes,diverse symptoms.A common clinical classification includes the frontal lobe form,corpus callosum form and posterior form.Lesions involved the medial frontal cortex,corpus callosum,parietal lobe,thalamus,etc.The patients with AHS should be given active imaging examination,specific analysis of its causes,and timely treatment to prevent misdiagnosis and delayed treatment.
Intervention therapy combined with bypass operation for multilevel atherosclerotic occlusive disease
2010, 35(7): 684-686.
Abstract:
Objective: To explore an effective procedure for multilevel atherosclerotic occlusive disease.Methods: Iliac angioplasty and stenting combined with femoro-popliteal bypass were performed on 19 patients with lower extremity multilevel atherosclerotic occlusive disease.Iliac angioplasty and stent procedures were applied to 19 cases,femoro-popliteal bypass with artificial vessels to 12 cases,femoro-popliteal bypass by great saphenous vein to 4 cases and femoro-femoral bypass to 3 cases.Results: The operation was successful in all the cases and no wound-related complications occurred.The mean postoperative ankle-brachial index (0.73±0.17) was much better than the preoperative index (0.23±0.12) (P<0.01).The followup time was 18 months on the average;the clinical symptoms in all the cases improved obviously,only 2 cases remained intermittent claudication.Conclusions: Intracavity intervention therapy combined with bypass operation is effective for treatment of lower extremity multilevel atherosclerotic occlusive disease.
Objective: To explore an effective procedure for multilevel atherosclerotic occlusive disease.Methods: Iliac angioplasty and stenting combined with femoro-popliteal bypass were performed on 19 patients with lower extremity multilevel atherosclerotic occlusive disease.Iliac angioplasty and stent procedures were applied to 19 cases,femoro-popliteal bypass with artificial vessels to 12 cases,femoro-popliteal bypass by great saphenous vein to 4 cases and femoro-femoral bypass to 3 cases.Results: The operation was successful in all the cases and no wound-related complications occurred.The mean postoperative ankle-brachial index (0.73±0.17) was much better than the preoperative index (0.23±0.12) (P<0.01).The followup time was 18 months on the average;the clinical symptoms in all the cases improved obviously,only 2 cases remained intermittent claudication.Conclusions: Intracavity intervention therapy combined with bypass operation is effective for treatment of lower extremity multilevel atherosclerotic occlusive disease.
2010, 35(7): 686-688.
Abstract:
Objective: To compare the effect of esmolol (ESM) and/or fentanil on hemodynamic response in tracheal intubation.Methods: One hundred and two adult patients were randomly divided into three groups.Group A and B were administered 2 mg/kg ESM,and group B and C were given 2 μg/kg fentanil before intubation.Tracheal intubation was performed with 0.3 mg/kg etomidate,0.1 mg/kg midazolam and 0.1 mg/kg vecuronium.The SBP,DBP and HR were measured before and after intubation and the RPP was calculated.Results: The SBP,DBP and RPP in group B decreased 1,3 and 5 min after intubation (P<0.05 to P<0.01).The HR in group A and B was lower than that in group C (P<0.01).Conclusions: ESM 2 mg/kg may reduce the hemodynamic response to a certain degree,and ESM 2 mg/kg and fentanil 2 μg/kg can effectively attenuate the hemodynamic response in intubation.
Objective: To compare the effect of esmolol (ESM) and/or fentanil on hemodynamic response in tracheal intubation.Methods: One hundred and two adult patients were randomly divided into three groups.Group A and B were administered 2 mg/kg ESM,and group B and C were given 2 μg/kg fentanil before intubation.Tracheal intubation was performed with 0.3 mg/kg etomidate,0.1 mg/kg midazolam and 0.1 mg/kg vecuronium.The SBP,DBP and HR were measured before and after intubation and the RPP was calculated.Results: The SBP,DBP and RPP in group B decreased 1,3 and 5 min after intubation (P<0.05 to P<0.01).The HR in group A and B was lower than that in group C (P<0.01).Conclusions: ESM 2 mg/kg may reduce the hemodynamic response to a certain degree,and ESM 2 mg/kg and fentanil 2 μg/kg can effectively attenuate the hemodynamic response in intubation.
2010, 35(7): 689-691.
Abstract:
Objective: To explore a surgical method of idiopathic congenital nystagmus with horizontal strabismus.Methods: Twenty-eight cases suffered from idiopathic congenital nystagmus with horizontal strabismus were applied with the operation correction of neutral zones in the main eye,and horizontal strabismus correction in another eye with posterior fixation suture of the rectus muscles.Results: Of the 28 cases,visual acuity of all the main eyes was inproved over two lines than before.Compensatory head-posture was disappeared for 26 cases (92.86%).Both eyes look in the front directed no nystagmus or slight nystagmus for 26 cases (92.86%).The binocular vision for some cases were in proved after operation.Conclusions: The operation correction of neutral zones in the main eye and horizontal strabismus correction in another eye for idiopathic congenital nystagmus with horizontal correction and posterior fixation suture of the rectus muscles could not only improve the visual acuity,but also basically cure the nystagmus looking in the front.
Objective: To explore a surgical method of idiopathic congenital nystagmus with horizontal strabismus.Methods: Twenty-eight cases suffered from idiopathic congenital nystagmus with horizontal strabismus were applied with the operation correction of neutral zones in the main eye,and horizontal strabismus correction in another eye with posterior fixation suture of the rectus muscles.Results: Of the 28 cases,visual acuity of all the main eyes was inproved over two lines than before.Compensatory head-posture was disappeared for 26 cases (92.86%).Both eyes look in the front directed no nystagmus or slight nystagmus for 26 cases (92.86%).The binocular vision for some cases were in proved after operation.Conclusions: The operation correction of neutral zones in the main eye and horizontal strabismus correction in another eye for idiopathic congenital nystagmus with horizontal correction and posterior fixation suture of the rectus muscles could not only improve the visual acuity,but also basically cure the nystagmus looking in the front.
2010, 35(7): 691-692.
Abstract:
Objective: To evaluate the efficacy of mifepristone and gestrinone in treatment of patients with endometriosis after operation.Methods: One hundred and thirty-eight cases with endometriosis were randomly divided into three groups:Forty-six cases in mifepristone (12.5 mg/d) group,46 cases in gestrione (2.5 mg,twice a week) group,the treatment in these two groups was started at one week after the operation for 6 months and other 46 cases were in control group (without drug treatment),all of them were regularly followed-up.Results: The remission of symptoms of dysmenorrhoea in varying degree were seen in patients of these 3 groups.The complete remission rates in patients of mifepristone and gestrinone groups were significantly higher than of control group (P<0.01).The recurrence rates in mifepristone and gestrinone groups were significantly lower than of control group (P<0.01).Conclusions: The consolidation therapy with mifepristone and gestrinone for post-operation treatment of endometriosis is safe and effective with less adverse reactions.
Objective: To evaluate the efficacy of mifepristone and gestrinone in treatment of patients with endometriosis after operation.Methods: One hundred and thirty-eight cases with endometriosis were randomly divided into three groups:Forty-six cases in mifepristone (12.5 mg/d) group,46 cases in gestrione (2.5 mg,twice a week) group,the treatment in these two groups was started at one week after the operation for 6 months and other 46 cases were in control group (without drug treatment),all of them were regularly followed-up.Results: The remission of symptoms of dysmenorrhoea in varying degree were seen in patients of these 3 groups.The complete remission rates in patients of mifepristone and gestrinone groups were significantly higher than of control group (P<0.01).The recurrence rates in mifepristone and gestrinone groups were significantly lower than of control group (P<0.01).Conclusions: The consolidation therapy with mifepristone and gestrinone for post-operation treatment of endometriosis is safe and effective with less adverse reactions.
2010, 35(7): 693-695.
Abstract:
Objective: To evaluate the clinical effect of gamma globulin,dopamine and dobutamine combined in the treatment of infants and children with severe pneumonia.Methods: Sixty patients with severe pneumonia were randomly divided into treatment group and control group.All the patients were administered antibiotics,anti-virus,oxygen,suction,cardiac,diuretic,maintaining acid-base and electrolyte equilibrium.In addition to the conventional therapy,the treatment group were given intravenous gamma globulin 300-500 mg·kg-1·d-1 for 3 days,dopamine and dobutamine 3-5 μg·kg-1·min-1 with 5% glucose by infusion pumps for 2-3 days.Results: The response rate of treatment group was superior to that of control group (P<0.01).Conclusions: The combination therapy of gamma globulin,dopamine and dobutamine may improve the curative effect on patients with severe pneumonia.
Objective: To evaluate the clinical effect of gamma globulin,dopamine and dobutamine combined in the treatment of infants and children with severe pneumonia.Methods: Sixty patients with severe pneumonia were randomly divided into treatment group and control group.All the patients were administered antibiotics,anti-virus,oxygen,suction,cardiac,diuretic,maintaining acid-base and electrolyte equilibrium.In addition to the conventional therapy,the treatment group were given intravenous gamma globulin 300-500 mg·kg-1·d-1 for 3 days,dopamine and dobutamine 3-5 μg·kg-1·min-1 with 5% glucose by infusion pumps for 2-3 days.Results: The response rate of treatment group was superior to that of control group (P<0.01).Conclusions: The combination therapy of gamma globulin,dopamine and dobutamine may improve the curative effect on patients with severe pneumonia.
2010, 35(7): 695-696.
Abstract:
Objective: To explore an effective procedure for management of hepatolithiasis.Methods: The clinical data of 43 patients with hepatolithiasis were analyzed retrospectively.All the cases were treated by regular hepatotomy combined with choledchoscope according to the stone location.Results: No improvement was observed in 2 cases.One of them occasionally had cholangitis,and the other had residual stones and recurrent cholangitis which needed reoperation.Conclusions: The procedure of regular hepatotomy combined with choledochoscope is safe and effective,and may significantly reduce the rate of residual stones.
Objective: To explore an effective procedure for management of hepatolithiasis.Methods: The clinical data of 43 patients with hepatolithiasis were analyzed retrospectively.All the cases were treated by regular hepatotomy combined with choledchoscope according to the stone location.Results: No improvement was observed in 2 cases.One of them occasionally had cholangitis,and the other had residual stones and recurrent cholangitis which needed reoperation.Conclusions: The procedure of regular hepatotomy combined with choledochoscope is safe and effective,and may significantly reduce the rate of residual stones.
2010, 35(7): 697-698.
Abstract:
Objective: To observe the effect of electro-acupuncture combined with scalp acupuncture and needle implant on hemifacial spasm.Methods: Thirty-eight cases of facial spasm were treated with electro-acupuncture combined with scalp acupuncture and needle implan.The outcome was compared with that of 32 cases treated by conventional method.Results: The cure rate of the treatment group was 28.95%,and the total effective rate was 89.47%.The cure rate of the conventional group was 12.50%,and the total effective rate was 71.88%.The difference was significant between the two groups (P<0.05).Conclusions: The electro-acupuncture combined with scalp acupuncture and needle implant is effective in treatment of hemifacial spasm.Being easy to operate,it is worth bpopularizing in clinical paractice.
Objective: To observe the effect of electro-acupuncture combined with scalp acupuncture and needle implant on hemifacial spasm.Methods: Thirty-eight cases of facial spasm were treated with electro-acupuncture combined with scalp acupuncture and needle implan.The outcome was compared with that of 32 cases treated by conventional method.Results: The cure rate of the treatment group was 28.95%,and the total effective rate was 89.47%.The cure rate of the conventional group was 12.50%,and the total effective rate was 71.88%.The difference was significant between the two groups (P<0.05).Conclusions: The electro-acupuncture combined with scalp acupuncture and needle implant is effective in treatment of hemifacial spasm.Being easy to operate,it is worth bpopularizing in clinical paractice.
2010, 35(7): 699-701.
Abstract:
Objective: To investigate the effect of MIPPO technology combined with locking compression plate (LCP) fixation in treatment of proximal tibial comminuted fracture.Methods: Twenty-five patients with comminuted fracture of the proximal tibial were managed by MIPPO technology combined with LCP internal fixation.Results: Primary healing of the incision and the fracture was achieved in all the 25 cases.No delayed union or nonunion occurred.The knee-ankle-joint function of the limbs recovered well.Conclusions: MIPPO technology combined with LCP fixation tends to become the best choice for treatment of proximal tibial comminuted fractures.
Objective: To investigate the effect of MIPPO technology combined with locking compression plate (LCP) fixation in treatment of proximal tibial comminuted fracture.Methods: Twenty-five patients with comminuted fracture of the proximal tibial were managed by MIPPO technology combined with LCP internal fixation.Results: Primary healing of the incision and the fracture was achieved in all the 25 cases.No delayed union or nonunion occurred.The knee-ankle-joint function of the limbs recovered well.Conclusions: MIPPO technology combined with LCP fixation tends to become the best choice for treatment of proximal tibial comminuted fractures.
2010, 35(7): 701-702.
Abstract:
Objective: To evaluate the curative effect of antivirus treatment on acquired immune deficiency syndrome (AIDS).Methods: One hundred and thirty-eight AIDS patients were administered highly active anti-retroviral medicines freely supplied by the national government,and the CD4T cells of the cases were detected regularly.Results: The CD4T cells increased the most rapidly after 3 months' treatment and reached (254.32±98.76)/mm3 after 2 years.The opportunistic infection was effectively controlled;the survival rate reached 86.36%.Conclusions: The immune function of the AIDS patients is enhanced significantly and the opportunistic infection is controlled effectively.AIDS patients should resort to the highly active anti-retroviral therapy as soon as possible.
Objective: To evaluate the curative effect of antivirus treatment on acquired immune deficiency syndrome (AIDS).Methods: One hundred and thirty-eight AIDS patients were administered highly active anti-retroviral medicines freely supplied by the national government,and the CD4T cells of the cases were detected regularly.Results: The CD4T cells increased the most rapidly after 3 months' treatment and reached (254.32±98.76)/mm3 after 2 years.The opportunistic infection was effectively controlled;the survival rate reached 86.36%.Conclusions: The immune function of the AIDS patients is enhanced significantly and the opportunistic infection is controlled effectively.AIDS patients should resort to the highly active anti-retroviral therapy as soon as possible.
2010, 35(7): 703-704.
Abstract:
Objective: To investigate the relationship between HLA-B27 and ankylosing spondylitis in patients from the north of Anhui province.Methods: The method of enzyme-linked immunosorbent assay was used to determine the HLA-B27 in 27 patients with AS from north Anhui.Results: HLA-B27 (+)was more frequently detected in the male patients than in the female,while HLA-B27 (-)was more often seen in the female patients than in the male.The difference was distinct between the two groups (P=0.001).The B27 (+)group usually demonstrated central axis joints symptoms,while the B27 (-)group periphery joints symptoms.Before treatment,the level of erythrocyte sedimentation and C-reactive protein of B27 (+)group was higher than that of B27 (-)group (P<0.05 and P<0.01).And after 3 to 6 months' treatment,the level of erythrocyte sedimentation and C-reactive protein in B27 (+)group was higher than that in B27 (-)group (P<0.001).There was no significant difference in the age between the two groups (P>0.05).Conclusions: There is relationship between the gender and the severity of ankylosing pondylitis in the Han nationality of north Anhui.Ankylosing pondylitis with HLA-B27 (+)is more difficult to control.
Objective: To investigate the relationship between HLA-B27 and ankylosing spondylitis in patients from the north of Anhui province.Methods: The method of enzyme-linked immunosorbent assay was used to determine the HLA-B27 in 27 patients with AS from north Anhui.Results: HLA-B27 (+)was more frequently detected in the male patients than in the female,while HLA-B27 (-)was more often seen in the female patients than in the male.The difference was distinct between the two groups (P=0.001).The B27 (+)group usually demonstrated central axis joints symptoms,while the B27 (-)group periphery joints symptoms.Before treatment,the level of erythrocyte sedimentation and C-reactive protein of B27 (+)group was higher than that of B27 (-)group (P<0.05 and P<0.01).And after 3 to 6 months' treatment,the level of erythrocyte sedimentation and C-reactive protein in B27 (+)group was higher than that in B27 (-)group (P<0.001).There was no significant difference in the age between the two groups (P>0.05).Conclusions: There is relationship between the gender and the severity of ankylosing pondylitis in the Han nationality of north Anhui.Ankylosing pondylitis with HLA-B27 (+)is more difficult to control.
2010, 35(7): 705-706.
Abstract:
Objective: To investigate the effect of hepatectomy in management of hepatolithiasis.Methods: The clinical data of 65 cases of hepatolithiasis having received hepatectomy were analyzed of the operation indication,time selection,surgical approaches,complications and the preventive measures.Results: No one died in the operation.Wound infection occurred in 2 cases,incision fat liquefaction in 2 cases,biliary fistula in 2 cases and stone recurrence in 2 cases.Conclusions: Hepatic lobectomy is an effective procedure for treatment of hepatolithiasis with a low rate of reliquus concrement,recidivism and complication.
Objective: To investigate the effect of hepatectomy in management of hepatolithiasis.Methods: The clinical data of 65 cases of hepatolithiasis having received hepatectomy were analyzed of the operation indication,time selection,surgical approaches,complications and the preventive measures.Results: No one died in the operation.Wound infection occurred in 2 cases,incision fat liquefaction in 2 cases,biliary fistula in 2 cases and stone recurrence in 2 cases.Conclusions: Hepatic lobectomy is an effective procedure for treatment of hepatolithiasis with a low rate of reliquus concrement,recidivism and complication.
2010, 35(7): 707-709.
Abstract:
Objective: To investigate the clinical effect about multipoint forming technology of titanium mesh for individual shaping for repairing skull defects.Methods: Shaping titanium meshes were properly made with multipoint forming technology assisted by computer for the 16 patients with defected skull.Shaping workload during operation,anesthesia time,operating time and molding quality were observed,and satisfaction degrees with the operations were investigated.Results: The shaping workload,anesthesia time and operating time were significantly decreased,and 93.7% patients were satisfied with the operation.Conclusions: The clinical effect about titanium meshes shaped by multipoint forming technology for repairing skull defects is perfect,and worthy of clinical application.
Objective: To investigate the clinical effect about multipoint forming technology of titanium mesh for individual shaping for repairing skull defects.Methods: Shaping titanium meshes were properly made with multipoint forming technology assisted by computer for the 16 patients with defected skull.Shaping workload during operation,anesthesia time,operating time and molding quality were observed,and satisfaction degrees with the operations were investigated.Results: The shaping workload,anesthesia time and operating time were significantly decreased,and 93.7% patients were satisfied with the operation.Conclusions: The clinical effect about titanium meshes shaped by multipoint forming technology for repairing skull defects is perfect,and worthy of clinical application.
2010, 35(7): 709-711.
Abstract:
Objective: To compare the effects of all-trans retinoic acid combined with Bai Xue Kang or arsenic trioxide on acute promyelocytic leukemia.Methods: Forty-two cases of acute promyelocytic leukemia were divided into Bai Xue Kang group (all-Trans retinoic acid combined with Bai Xue Kang)and arsenic trioxide group (all-trans retinoic acid combined with arsenic trioxide).The remission,mortality rate,change of hemogram,coagulation index and adverse reaction were compared between the two groups.Results: Both groups had no statistical difference in clinical effect and adverse reaction (P>0.05).Conclusions: The clinical effects of all-trans retinoic acid combined with Bai Xue Kang or arsenic trioxide have no significant difference in treatment of acute promyelocytic leukemia,but Bai Xue Kang is more cost-effective and has less adverse reaction,so is worth popularizing.
Objective: To compare the effects of all-trans retinoic acid combined with Bai Xue Kang or arsenic trioxide on acute promyelocytic leukemia.Methods: Forty-two cases of acute promyelocytic leukemia were divided into Bai Xue Kang group (all-Trans retinoic acid combined with Bai Xue Kang)and arsenic trioxide group (all-trans retinoic acid combined with arsenic trioxide).The remission,mortality rate,change of hemogram,coagulation index and adverse reaction were compared between the two groups.Results: Both groups had no statistical difference in clinical effect and adverse reaction (P>0.05).Conclusions: The clinical effects of all-trans retinoic acid combined with Bai Xue Kang or arsenic trioxide have no significant difference in treatment of acute promyelocytic leukemia,but Bai Xue Kang is more cost-effective and has less adverse reaction,so is worth popularizing.
2010, 35(7): 712-714.
Abstract:
Objective: To evaluate the preserved amniotic membrane transplantation in treatment of pterygium.Methods: A total of 25 eyes with pterygium underwent transplantation with preserved amniotic membrane.The postoperative reaction,the graft vitality and the recurrence of pterygium were observed.Results: No acute rejection or blepharosynechic were observed.The grafts grew well,and only one recurrence was found during the follow-up of 1 year.Conclusions: Transplantation with the preserved amniotic membrane is safe and effective for treatment of pterygium.
Objective: To evaluate the preserved amniotic membrane transplantation in treatment of pterygium.Methods: A total of 25 eyes with pterygium underwent transplantation with preserved amniotic membrane.The postoperative reaction,the graft vitality and the recurrence of pterygium were observed.Results: No acute rejection or blepharosynechic were observed.The grafts grew well,and only one recurrence was found during the follow-up of 1 year.Conclusions: Transplantation with the preserved amniotic membrane is safe and effective for treatment of pterygium.
2010, 35(7): 714-716.
Abstract:
Objective: To evaluate the value of transthoracic echocardiography (TTE) in transcatheter closure of congenital heart diseases patients choice before operation,monitoring in operation and observation treatment effect after operation.Methods: Thirty-seven patients with congenital heart diseases were selected by echocardiography before transcatheter closure,in which there were 20 cases of secundum atrial septal defect (ASD),10 cases of ventricular septal defect (VSD),and 7 cases of patent ductus arteriosus (PDA),all of the patients underwent transcatheter closure using the Amplatzer occluder,the diameter occluder device is 2-4 mm wider than measure of echocardiography.The Amplatzer occluder closure procedure which monitored by X-ray and TTE was observed.TTE was performed 1 day,1 week,1 month and 6 months after operation,in order to measure the size of heart and to find whether there were shunts in atrial septum,ventricular septum,large arteries lever and whether the occluder was dropted.Results: The successful transcatheter closure of ASD,VSD and PDA were 19,10,7 cases respectively.One day after operation on TTE,there a slight shunt was detected in 1 case of ASD,a little regurgitation was remained in tricuspid valve of 1 VSD patient,two VSD patients developed a variety of heart block.No shunt was detected in all cases 1-6 months later.Conclusions: TTE has the great usefulness in choosing suitable patients,selecting the size of occluder,examining whether the location is suitable in operation and whether has the residual shunts after operation.It is also important for evaluation of curative effects.
Objective: To evaluate the value of transthoracic echocardiography (TTE) in transcatheter closure of congenital heart diseases patients choice before operation,monitoring in operation and observation treatment effect after operation.Methods: Thirty-seven patients with congenital heart diseases were selected by echocardiography before transcatheter closure,in which there were 20 cases of secundum atrial septal defect (ASD),10 cases of ventricular septal defect (VSD),and 7 cases of patent ductus arteriosus (PDA),all of the patients underwent transcatheter closure using the Amplatzer occluder,the diameter occluder device is 2-4 mm wider than measure of echocardiography.The Amplatzer occluder closure procedure which monitored by X-ray and TTE was observed.TTE was performed 1 day,1 week,1 month and 6 months after operation,in order to measure the size of heart and to find whether there were shunts in atrial septum,ventricular septum,large arteries lever and whether the occluder was dropted.Results: The successful transcatheter closure of ASD,VSD and PDA were 19,10,7 cases respectively.One day after operation on TTE,there a slight shunt was detected in 1 case of ASD,a little regurgitation was remained in tricuspid valve of 1 VSD patient,two VSD patients developed a variety of heart block.No shunt was detected in all cases 1-6 months later.Conclusions: TTE has the great usefulness in choosing suitable patients,selecting the size of occluder,examining whether the location is suitable in operation and whether has the residual shunts after operation.It is also important for evaluation of curative effects.
2010, 35(7): 717-718.
Abstract:
Objective: To evaluate the efficacy of interventional therapy for treatment of digestive tract hemorrhage.Methods: All the 35 patients were performed arterial digital subtraction angiography,infused reptilase and embolized with gelfoam.Twenty-one cases with portal hypertension underwent percutaneous vena embolization or (and)partial splenic artery embolization;6 cases of obscure tract hemorrhage received perfusion of reptilase in artery only.Results: The bleeding was stopped in all the cases.Conclusions: The procedures of arterial perfusion,perfusion plus embolization,percutaneous vena embolization and partial spleen embolization are effective for treatment of digestive tract hemorrhage.
Objective: To evaluate the efficacy of interventional therapy for treatment of digestive tract hemorrhage.Methods: All the 35 patients were performed arterial digital subtraction angiography,infused reptilase and embolized with gelfoam.Twenty-one cases with portal hypertension underwent percutaneous vena embolization or (and)partial splenic artery embolization;6 cases of obscure tract hemorrhage received perfusion of reptilase in artery only.Results: The bleeding was stopped in all the cases.Conclusions: The procedures of arterial perfusion,perfusion plus embolization,percutaneous vena embolization and partial spleen embolization are effective for treatment of digestive tract hemorrhage.
2010, 35(7): 719-721.
Abstract:
Objective: To investigate the psychological situation of the relatives of mental illness patients with dangerous behavior.Methods: Sixty relatives of mental illness patients in the rural areas of Huaiyuan county treated in our hospital were randomly selected,and their psychological situation was surveyed by SCL-90.Results: The positive score of SCL-90 in the relative of patients with serious mental illness was obviously higher than that of normal subjects,and all the factorial scores were significantly higher than those of normal subjects.The difference was statistically significant (P<0.001~P<0.05).The depression factors in female relatives were significantly higher than those of male relatives (P<0.05).Conclusions: There are serious psychological problems in the relatives of patients with serious mental illness in rural areas,which is significantly higher in female relatives than in the male members.In order to improve the prognosis of patients with dangerous behavior in rural areas,mental intervention should be extended to the relatives of mental illness patients,particularly the female relatives.
Objective: To investigate the psychological situation of the relatives of mental illness patients with dangerous behavior.Methods: Sixty relatives of mental illness patients in the rural areas of Huaiyuan county treated in our hospital were randomly selected,and their psychological situation was surveyed by SCL-90.Results: The positive score of SCL-90 in the relative of patients with serious mental illness was obviously higher than that of normal subjects,and all the factorial scores were significantly higher than those of normal subjects.The difference was statistically significant (P<0.001~P<0.05).The depression factors in female relatives were significantly higher than those of male relatives (P<0.05).Conclusions: There are serious psychological problems in the relatives of patients with serious mental illness in rural areas,which is significantly higher in female relatives than in the male members.In order to improve the prognosis of patients with dangerous behavior in rural areas,mental intervention should be extended to the relatives of mental illness patients,particularly the female relatives.
2010, 35(7): 721-723.
Abstract:
Objective: To explore the method of improving the teaching quality of Enzyme Engineering by a serious of effective measures.Methods: A serious of measures was taken to improve the practical and academic quality of Enzyme Engineering teaching,such as optimizing teaching contents,refine teaching methods and means.Results: The students'interesting was improved by optimizing teaching contents and refine teaching methods.Meanwhile,the students'practical ability was improved through carrying out the biological comprehensive experiments.Conclusions: Through the reformation of teaching content and method of Enzyme Engineering,teaching,the students' ability of self-study and mastering knowledge can be improved,and the students' ability to apply comprehensive knowledge and solve practical problems can be enhanced.
Objective: To explore the method of improving the teaching quality of Enzyme Engineering by a serious of effective measures.Methods: A serious of measures was taken to improve the practical and academic quality of Enzyme Engineering teaching,such as optimizing teaching contents,refine teaching methods and means.Results: The students'interesting was improved by optimizing teaching contents and refine teaching methods.Meanwhile,the students'practical ability was improved through carrying out the biological comprehensive experiments.Conclusions: Through the reformation of teaching content and method of Enzyme Engineering,teaching,the students' ability of self-study and mastering knowledge can be improved,and the students' ability to apply comprehensive knowledge and solve practical problems can be enhanced.
2010, 35(7): 724-726.
Abstract:
Objective: To observe the effect of joyful teaching in the experiment class of Nursing Science Foundation.Methods: Two hudred and eleven nurse students of grade 2007 were randomly divide into experimental group (110 students)and comparison group (101 students).Joyful teaching was applied to the experimental group while traditional teaching to the comparison group.At the end of the course,manipulation exam was carried out in both groups,and the teaching quality was surveyed and evaluated in the experimental group.Results: The performance record of the experimental group was much better than that of the comparison group (P<0.05).96.36% of the students in the experimental group were satisfactory to the teaching method,and 100% students thought it worthwhile to introduce joyful teaching to the class.Conclusions: Which may promote the communication and interaction between teachers and students,motivate the students' enthusiasm to study,cultivate the students' innovation ability and improve the their ability of manipulation and problem-solving.
Objective: To observe the effect of joyful teaching in the experiment class of Nursing Science Foundation.Methods: Two hudred and eleven nurse students of grade 2007 were randomly divide into experimental group (110 students)and comparison group (101 students).Joyful teaching was applied to the experimental group while traditional teaching to the comparison group.At the end of the course,manipulation exam was carried out in both groups,and the teaching quality was surveyed and evaluated in the experimental group.Results: The performance record of the experimental group was much better than that of the comparison group (P<0.05).96.36% of the students in the experimental group were satisfactory to the teaching method,and 100% students thought it worthwhile to introduce joyful teaching to the class.Conclusions: Which may promote the communication and interaction between teachers and students,motivate the students' enthusiasm to study,cultivate the students' innovation ability and improve the their ability of manipulation and problem-solving.
2010, 35(7): 728-730.
Abstract:
Objective: To sum up the experience in nutrition support nursing of severely burned patients.Methods: At the end of shock stage,early gastrointestinal nutrition support was applied.On day 4 to 7,intravenous nutritional fluid was supplied as the main energy source,and then adequate protein,amino acids and lipid emulsions were administered.Results: No malnutrition,loss of body weight or severe complications occurred.All the 68 patients were cured.The wounds healed in 36 to 82 days.Conclusions: Gastrointestinal and intravenous supply of nutrition should be combined,and appropriated nursing is essential in treatment of severely burned patients.
Objective: To sum up the experience in nutrition support nursing of severely burned patients.Methods: At the end of shock stage,early gastrointestinal nutrition support was applied.On day 4 to 7,intravenous nutritional fluid was supplied as the main energy source,and then adequate protein,amino acids and lipid emulsions were administered.Results: No malnutrition,loss of body weight or severe complications occurred.All the 68 patients were cured.The wounds healed in 36 to 82 days.Conclusions: Gastrointestinal and intravenous supply of nutrition should be combined,and appropriated nursing is essential in treatment of severely burned patients.
2010, 35(7): 731-733.
Abstract:
Objective: To compare the effects of different humidification on patients receiving tracheotomy.Methods: Forty patients receiving tracheotomy were randomly divided into two groups,20 patients in each.The control group were given conventional humidification,and the experimental group were administered necessary humidification after evaluation of the sputamentum.The outcome was compared between the two groups.Results: The effects of the experiment group were superior to that of the control (P<0.01).The occurrence of irritating coughs and mucous membrane hemorrhages in the experimental group were lower than that in the normal control (P<0.05 to P<0.01).The times of aspiration of sputum in the experimental group were less than those of the normal control (P<0.01).Conclusions: It is reasonable and safe to administer humidification volume after evaluation of the sputamentum,which may decrease the times of aspiration of sputum and lighten the nurses' workload.
Objective: To compare the effects of different humidification on patients receiving tracheotomy.Methods: Forty patients receiving tracheotomy were randomly divided into two groups,20 patients in each.The control group were given conventional humidification,and the experimental group were administered necessary humidification after evaluation of the sputamentum.The outcome was compared between the two groups.Results: The effects of the experiment group were superior to that of the control (P<0.01).The occurrence of irritating coughs and mucous membrane hemorrhages in the experimental group were lower than that in the normal control (P<0.05 to P<0.01).The times of aspiration of sputum in the experimental group were less than those of the normal control (P<0.01).Conclusions: It is reasonable and safe to administer humidification volume after evaluation of the sputamentum,which may decrease the times of aspiration of sputum and lighten the nurses' workload.
2010, 35(7): 733-734.
Abstract:
Objective: To observe the effect of artificial nose in airway humidification of ventilated patients.Methods: One hundred and eight patients using mechanical ventilation were randomly divided into two groups:artificial nose group and routine airway humidification group.The sputum viscosity of the patients was observed,and the effects of the airway humidification were compared between the two groups.Results: The cases with degree Ⅰ sputum accounted for 66.67% and 27.78% in the artificial nose group and the routine airway humidification group,respectively.The difference was significant (P<0.01).Conclusions: The artificial nose can ensure the tracheal humidity and warmth.
Objective: To observe the effect of artificial nose in airway humidification of ventilated patients.Methods: One hundred and eight patients using mechanical ventilation were randomly divided into two groups:artificial nose group and routine airway humidification group.The sputum viscosity of the patients was observed,and the effects of the airway humidification were compared between the two groups.Results: The cases with degree Ⅰ sputum accounted for 66.67% and 27.78% in the artificial nose group and the routine airway humidification group,respectively.The difference was significant (P<0.01).Conclusions: The artificial nose can ensure the tracheal humidity and warmth.
2010, 35(7): 735-736.
Abstract:
Objective: To explore the ways of identifying early signs of severe hand-foot-and-mouth disease (HFMD) in children and the nursing measures.Methods: The nervous,respiratory and circulation system of 32 children with severe HFMD disease were observed in addition to the routine disinfection,isolation,care of skin and oral cavity.All the cases were performed active treatment and intensive nursing.Results: Twenty-five cases were cured and 6 cases improved.Conclusions: Early identification of signs of severe HFMD,intensive monitoring,appropriate treatment and rational care are essential to elevate the cure rate of HFMD in children.
Objective: To explore the ways of identifying early signs of severe hand-foot-and-mouth disease (HFMD) in children and the nursing measures.Methods: The nervous,respiratory and circulation system of 32 children with severe HFMD disease were observed in addition to the routine disinfection,isolation,care of skin and oral cavity.All the cases were performed active treatment and intensive nursing.Results: Twenty-five cases were cured and 6 cases improved.Conclusions: Early identification of signs of severe HFMD,intensive monitoring,appropriate treatment and rational care are essential to elevate the cure rate of HFMD in children.
2010, 35(7): 737-739.
Abstract:
Objective: To evaluate the comfort care in patients with lumbar disc herniation in the application results.Methods: Ninety patients with lumbar disc herniation were randomly divided into comfortable care group and normal care groups,on the basis of the overall care,a lot of nursing methods such as treat,nursing and healthy education were adopted by the normal care group;comfort care group from the physical,psychological,social and other aspects,multi-angle to give a full range of comfort care,will be two sets of results comparison.Results: The effects of comfort care group were significantly better than the normal care group,the difference was statistically significant (P<0.01).Conclusions: Comfort care is a holistic,personalized,creative and effective care model is effective in patients with lumbar disc herniation nursing method.
Objective: To evaluate the comfort care in patients with lumbar disc herniation in the application results.Methods: Ninety patients with lumbar disc herniation were randomly divided into comfortable care group and normal care groups,on the basis of the overall care,a lot of nursing methods such as treat,nursing and healthy education were adopted by the normal care group;comfort care group from the physical,psychological,social and other aspects,multi-angle to give a full range of comfort care,will be two sets of results comparison.Results: The effects of comfort care group were significantly better than the normal care group,the difference was statistically significant (P<0.01).Conclusions: Comfort care is a holistic,personalized,creative and effective care model is effective in patients with lumbar disc herniation nursing method.
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