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2010 Vol. 35, No. 9
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2010, 35(9): 865-868.
Abstract:
Objective:To reconstruct and visualize the three-dimensional model of the precentral sulcus and its adjacent domains for stereotactic anatomy,interventional radiology and minimal invasive surgery.Methods:The precentral sulcus,longitudinal fissure,the lateral ventricle,the cerebrum surface profile of the head were identified and segmented on MRI transverse of six healthy volunteer's heads,and their three-dimensional models were reconstructed in 3D-Doctor software package with the method of surface rendering.Results:The first successful three-dimensional model of the precentral sulcus was reconstructed.The precentral sulcus,other interesting structures and their spatial relations were observed in three-dimensional virtual space in random angles.Conclusions:It is hoped that the three-dimensional reconstruction and visualization of the precentral sulcus based on the MRI would benefit for the study of neuroanatomy,stereotactic neurosurgery,remote imaging diagnosis and multimedia teaching.
Objective:To reconstruct and visualize the three-dimensional model of the precentral sulcus and its adjacent domains for stereotactic anatomy,interventional radiology and minimal invasive surgery.Methods:The precentral sulcus,longitudinal fissure,the lateral ventricle,the cerebrum surface profile of the head were identified and segmented on MRI transverse of six healthy volunteer's heads,and their three-dimensional models were reconstructed in 3D-Doctor software package with the method of surface rendering.Results:The first successful three-dimensional model of the precentral sulcus was reconstructed.The precentral sulcus,other interesting structures and their spatial relations were observed in three-dimensional virtual space in random angles.Conclusions:It is hoped that the three-dimensional reconstruction and visualization of the precentral sulcus based on the MRI would benefit for the study of neuroanatomy,stereotactic neurosurgery,remote imaging diagnosis and multimedia teaching.
2010, 35(9): 869-872.
Abstract:
Objective:To explore pathological structural changes in the kidney of diabetic rats and establish the rat model of diabetic nephropathy.Methods:Forty eight male Sprague-Dawley rats were randomly divided into control group and experimental group (24 for each).Twenty-four rats in the experiment group were intraperitoneally injected with streptozotocin to set up animal modal of diabetes.At 1,4,8 and 12 weeks,the were recovded weight,blood glucose,24-hour urine volume,24-hour urinary protein,kidney hypertrophy index and pathological changes of kidney.Results:The diabetic group was detected.The higher level (P<0.01) of blood glucose,more 24 hour urine and 24 hour urinary protein than the control group (P<0.01).The changes of kidney structure was obvious in light microscope.Conclusions:Kidney damage of diabetic rats had been induced by streptozotocin injection,and the rat model of diabetic was successively established.
Objective:To explore pathological structural changes in the kidney of diabetic rats and establish the rat model of diabetic nephropathy.Methods:Forty eight male Sprague-Dawley rats were randomly divided into control group and experimental group (24 for each).Twenty-four rats in the experiment group were intraperitoneally injected with streptozotocin to set up animal modal of diabetes.At 1,4,8 and 12 weeks,the were recovded weight,blood glucose,24-hour urine volume,24-hour urinary protein,kidney hypertrophy index and pathological changes of kidney.Results:The diabetic group was detected.The higher level (P<0.01) of blood glucose,more 24 hour urine and 24 hour urinary protein than the control group (P<0.01).The changes of kidney structure was obvious in light microscope.Conclusions:Kidney damage of diabetic rats had been induced by streptozotocin injection,and the rat model of diabetic was successively established.
2010, 35(9): 872-876.
Abstract:
Objective:To evaluate the inhibitory effect of RNA interference (RNAi) on the expression of epithelial cell adhesion molecule (EP-CAM) mRNA and protein in human gallbladder cancer cells.Methods:Four recombinant plasmids targeting human EP-CAM gene were transfected into GBC-SD cells by Lipofectamine 2000 after DNA sequencing;RT-PCR and Western blotting were used to detect the mRNA and protein expression of EP-CAM.Results:Four EP-CAM-targeted microRNA (miRNA) -1,-2,-3and-4 were successfully inserted into the plasmid vector,and the coding sequences of the obtained miRNA were consistent with the designed fragments.The results indicated that four recombinants plasmid could effectively knock down the expression of EP-CAM mRNA and protein in human gallbladder cancer cells.Conclusions:The recombinant plasmid pcDNATM6.2-GW/EmGFPmiR miRNA targeting human EP-CAM gene can effectively down-regulate the expression of EPCAM mRNA and protein in human GBC-SD cells.
Objective:To evaluate the inhibitory effect of RNA interference (RNAi) on the expression of epithelial cell adhesion molecule (EP-CAM) mRNA and protein in human gallbladder cancer cells.Methods:Four recombinant plasmids targeting human EP-CAM gene were transfected into GBC-SD cells by Lipofectamine 2000 after DNA sequencing;RT-PCR and Western blotting were used to detect the mRNA and protein expression of EP-CAM.Results:Four EP-CAM-targeted microRNA (miRNA) -1,-2,-3and-4 were successfully inserted into the plasmid vector,and the coding sequences of the obtained miRNA were consistent with the designed fragments.The results indicated that four recombinants plasmid could effectively knock down the expression of EP-CAM mRNA and protein in human gallbladder cancer cells.Conclusions:The recombinant plasmid pcDNATM6.2-GW/EmGFPmiR miRNA targeting human EP-CAM gene can effectively down-regulate the expression of EPCAM mRNA and protein in human GBC-SD cells.
2010, 35(9): 877-882.
Abstract:
Objective:To study the expressions of transforming growth factor-β1 (TGF-β1),thrombospondin-1 (TSP-1) and vascular endothelial growth factor (VEGF) in rat renal tissue in adenine induced chronic renal failure (CRF).Methods:Sixty male SD rats were randomly divided into two groups:model group (n=30),2.5% Adenine solution was administered by gastric garage daily;control group (n=30),the same volume torch solution was administered by gastric garage daily.At the 7th,14th and 21th day,ten rats in every group were sacrificed.Urine sample,blood sample and kidney tissue were reserved.The body weight (BW),kidney weight/body weight index (KI),the levels of 24 hours urine protein (24 h U-TP),N-acety1-β-D-glucosaminidase (NAG) in urine sample,blood urea nitrogen (BUN),serum creatinine (SCr) and blood albumin (ALB) in blood sample were examined.The histological changes of kidney were observed by light microscopy,and the expressions of TGF-β1,TSP-1,VEGF were examined by immunohistochemistrical method.Results:At the 7th day,rat BW in model group was increased slowly than that in control group (P<0.01);ALB was no significant change in these two groups.At the 14th and 21th day,BW and ALB in model group were decreased clearly than those in the same group at 7th day (P<0.01);At 7th,14th and 21th day,the levels of 24 h U-TP,NAG,BUN and SCr in model group were progressively increased (P<0.01).And the expressions of TGF-β1 and TSP-1 were also progressively increased.In control group,VEGF was broadly expressed in renal tubular epithelial cells and podocytes.With the aggravation of pathological injury in renal tubulointerstitial tissue,VEGF expression was decreased in model group.In different times in model group,the expressions of TGF-β1 in renal tubulointerstitial tissue and tubule were positive correlation (rs=0.940,P<0.01).The expression of VEGF in renal tubule was negative correlation with the expression of TGF-β1 in renal tubule (rs=-0.945,P<0.01) and TSP-1 in renal tubulointerstitial tissue (rs=-0.923,P<0.01).Conclusions:The increase of TSP-1-TGF-β1 axis expressions enhanced renal interstitial fibrosis and development,the TSP-1 may play an important role in adenine induced chronic renal failure;the decline of VEGF expression also led to renal interstitial fibrosis.
Objective:To study the expressions of transforming growth factor-β1 (TGF-β1),thrombospondin-1 (TSP-1) and vascular endothelial growth factor (VEGF) in rat renal tissue in adenine induced chronic renal failure (CRF).Methods:Sixty male SD rats were randomly divided into two groups:model group (n=30),2.5% Adenine solution was administered by gastric garage daily;control group (n=30),the same volume torch solution was administered by gastric garage daily.At the 7th,14th and 21th day,ten rats in every group were sacrificed.Urine sample,blood sample and kidney tissue were reserved.The body weight (BW),kidney weight/body weight index (KI),the levels of 24 hours urine protein (24 h U-TP),N-acety1-β-D-glucosaminidase (NAG) in urine sample,blood urea nitrogen (BUN),serum creatinine (SCr) and blood albumin (ALB) in blood sample were examined.The histological changes of kidney were observed by light microscopy,and the expressions of TGF-β1,TSP-1,VEGF were examined by immunohistochemistrical method.Results:At the 7th day,rat BW in model group was increased slowly than that in control group (P<0.01);ALB was no significant change in these two groups.At the 14th and 21th day,BW and ALB in model group were decreased clearly than those in the same group at 7th day (P<0.01);At 7th,14th and 21th day,the levels of 24 h U-TP,NAG,BUN and SCr in model group were progressively increased (P<0.01).And the expressions of TGF-β1 and TSP-1 were also progressively increased.In control group,VEGF was broadly expressed in renal tubular epithelial cells and podocytes.With the aggravation of pathological injury in renal tubulointerstitial tissue,VEGF expression was decreased in model group.In different times in model group,the expressions of TGF-β1 in renal tubulointerstitial tissue and tubule were positive correlation (rs=0.940,P<0.01).The expression of VEGF in renal tubule was negative correlation with the expression of TGF-β1 in renal tubule (rs=-0.945,P<0.01) and TSP-1 in renal tubulointerstitial tissue (rs=-0.923,P<0.01).Conclusions:The increase of TSP-1-TGF-β1 axis expressions enhanced renal interstitial fibrosis and development,the TSP-1 may play an important role in adenine induced chronic renal failure;the decline of VEGF expression also led to renal interstitial fibrosis.
2010, 35(9): 883-886.
Abstract:
Objective:To study the proportion of CD4+ CD25high regulatory T cells (Treg) in the peripheral blood of patients with gastric cancer and its clinical significance.Methods:The proportion and the phenotype of Treg cells in the peripheral blood of 50 gastric cancer patients and 20 healthy controls were determined by flow cytometry.In addition,the changes of Treg cell levels of 10 patients with gastric cancer were analyzed before and one week after the operation.Results:Compared with the healthy controls (3.41±1.13)%,the proportion of Treg cells in the peripheral blood of patients with gastric cancer was significantly increased (14.67±6.55)% (P<0.01).In addition,the CD4+ CD25high Treg cells expressed high levels of FOXP3,CD152 (CTLA-4),CD134 (OX40) and GITR.The Treg cell level in patients with gastric cancer was significantly reduced after the tumor was resection (P<0.05).Conclusions:The proportion of Treg cells is increased in the peripheral blood of patients with gastric cancer;The Treg cells may suppress the immune response against cancer and be related to the progress of the tumor.
Objective:To study the proportion of CD4+ CD25high regulatory T cells (Treg) in the peripheral blood of patients with gastric cancer and its clinical significance.Methods:The proportion and the phenotype of Treg cells in the peripheral blood of 50 gastric cancer patients and 20 healthy controls were determined by flow cytometry.In addition,the changes of Treg cell levels of 10 patients with gastric cancer were analyzed before and one week after the operation.Results:Compared with the healthy controls (3.41±1.13)%,the proportion of Treg cells in the peripheral blood of patients with gastric cancer was significantly increased (14.67±6.55)% (P<0.01).In addition,the CD4+ CD25high Treg cells expressed high levels of FOXP3,CD152 (CTLA-4),CD134 (OX40) and GITR.The Treg cell level in patients with gastric cancer was significantly reduced after the tumor was resection (P<0.05).Conclusions:The proportion of Treg cells is increased in the peripheral blood of patients with gastric cancer;The Treg cells may suppress the immune response against cancer and be related to the progress of the tumor.
2010, 35(9): 887-888.
Abstract:
Objective:To explore the clinical applications of laparoscopic assisted myomectomy for treatment of hysteromyoma.Methods:Forty seven patients with hysteromyoma were randomly divided into two groups.One group (26 cases) was performed with laparoscopic assisted myomectomy,the other group (21 cases) with laparoscopic myomectomy.The operation time,amount of bleeding,removal time of single myoma,postoperative intestinal recovery and hospitalization-time were compared between the two groups.Results:The operation time,amount of bleeding,removal time of single myoma in laparoscopic assisted myomectomy group were significantly superior to those in laparoscopic myomectomy group (P<0.05,respectively).The postoperative intestinal recovery and hospitalization-time was not significant between two groups.Conclusions:Compared with laparoscopic myomectomy,laparoscopic assisted myomectomy is supposed to be a more convenient and effective technique.
Objective:To explore the clinical applications of laparoscopic assisted myomectomy for treatment of hysteromyoma.Methods:Forty seven patients with hysteromyoma were randomly divided into two groups.One group (26 cases) was performed with laparoscopic assisted myomectomy,the other group (21 cases) with laparoscopic myomectomy.The operation time,amount of bleeding,removal time of single myoma,postoperative intestinal recovery and hospitalization-time were compared between the two groups.Results:The operation time,amount of bleeding,removal time of single myoma in laparoscopic assisted myomectomy group were significantly superior to those in laparoscopic myomectomy group (P<0.05,respectively).The postoperative intestinal recovery and hospitalization-time was not significant between two groups.Conclusions:Compared with laparoscopic myomectomy,laparoscopic assisted myomectomy is supposed to be a more convenient and effective technique.
A study on interference of N-Ras by RNA to enhance radiosensitivity of hepatoma carcinoma cell HepG2
2010, 35(9): 889-892.
Abstract:
Objective:To investigate the radiosensitivity of silencing N-Ras by RNA interference in Hepatoma carcinoma cell HepG2.Methods:N-Ras RNA interference (RNAi) vector was constructed by using pcDNA 6.2-GW/EmGFP-miR plasmid.The RNAi effect was detected by RT-PCR,Western blot,immunohistochemisty and MTT method.Survival curves for each cell line were obtained by measuring the colony forming abilities of irradiated cell populations.Results:After silencing the N-Ras by RNAi,the expression of N-Ras mRNA,N-Ras protein and the survival of hepatoma carcinoma cell HepG2 line were significant difference in statistics.Conclusions:RNAi targeting silenced N-Ras may increase the radiosensitivity of hepatoma carcinoma cell HepG2 line.
Objective:To investigate the radiosensitivity of silencing N-Ras by RNA interference in Hepatoma carcinoma cell HepG2.Methods:N-Ras RNA interference (RNAi) vector was constructed by using pcDNA 6.2-GW/EmGFP-miR plasmid.The RNAi effect was detected by RT-PCR,Western blot,immunohistochemisty and MTT method.Survival curves for each cell line were obtained by measuring the colony forming abilities of irradiated cell populations.Results:After silencing the N-Ras by RNAi,the expression of N-Ras mRNA,N-Ras protein and the survival of hepatoma carcinoma cell HepG2 line were significant difference in statistics.Conclusions:RNAi targeting silenced N-Ras may increase the radiosensitivity of hepatoma carcinoma cell HepG2 line.
2010, 35(9): 893-895.
Abstract:
Objective:To determine the minimal motor-blocking concentration (EC50) of epidural ropivacaine and bupivacaine in the postoperative epidural analgesia,and compare the relative potency of these drugs used in epidural space.Methods:Sixty ASA I women who went gynaecologic operation and requested epidural analgesia were randomized to receive either ropivacaine or bupivacaine.Epidural catheter was placed at L2-3 and advanced for 3cm in the epidural space in a cephalad direction.Each received a 10 ml bolus of epidural ropivacaine or bupivacaine.Half an hour before and after the bolus,take a Bromage score to compare.Up-down sequential allocation was used to determine subsequent concentration:to increase the concentration one level if the previous woman did not respond and to reduce the concentration one level if the previous woman did respond.The up-down sequences were analyzed by using the Brownlee method to quantify the minimal motor-blocking local analgesic concentration.Results:The ropivacaine was 0.706% and for bupivacaine was 0.443% with a ropivacaine/bupivacaine potency ratio of 0.63 (95% CI,0.60-0.66).Conclusions:Ropivacaine was significantly less potent for motor block,at 63% that of bupivacaine.
Objective:To determine the minimal motor-blocking concentration (EC50) of epidural ropivacaine and bupivacaine in the postoperative epidural analgesia,and compare the relative potency of these drugs used in epidural space.Methods:Sixty ASA I women who went gynaecologic operation and requested epidural analgesia were randomized to receive either ropivacaine or bupivacaine.Epidural catheter was placed at L2-3 and advanced for 3cm in the epidural space in a cephalad direction.Each received a 10 ml bolus of epidural ropivacaine or bupivacaine.Half an hour before and after the bolus,take a Bromage score to compare.Up-down sequential allocation was used to determine subsequent concentration:to increase the concentration one level if the previous woman did not respond and to reduce the concentration one level if the previous woman did respond.The up-down sequences were analyzed by using the Brownlee method to quantify the minimal motor-blocking local analgesic concentration.Results:The ropivacaine was 0.706% and for bupivacaine was 0.443% with a ropivacaine/bupivacaine potency ratio of 0.63 (95% CI,0.60-0.66).Conclusions:Ropivacaine was significantly less potent for motor block,at 63% that of bupivacaine.
2010, 35(9): 896-898.
Abstract:
Objective:To observe the analgesic and sedative effects of sufentanil and remifentanil during and after pediatric tonsillectomy and adenoidectomy surgery.Methods:One hundred patients involved in selective operation were chosen and divided into two groups randomly:sufentanil group (S group,n=50) and remifentanil group (R group,n=50).Patients in S group were rapidly induced by 0.2 μg/kg sufentanil,and were maintained with 0.2 μg·kg-1·h-1 in the operation.Sufentanil was withdrawn 30 min before the operation completed.Patients in R group were rapidly induced by 2 μg/kg remifentanil,and were maintained with 6 μg·kg-1·h-1 in the operation.Remifentanil was withdrawn 5 min before the operation completed.The hemodynamic indexes during and after the operation as well as the postoperative sedative degree of patients in the two groups were respectively observed.Results:No significant difference of hemodynamic indexes during the operation was observed between the two groups (P>0.05).No obvious difference was shown between the mean arterial pressure 5 min after removing tube in S group and the basic values;and a statistical difference was shown in R group (P<0.01).The Ramsay score of children in S group after operation was more appropriate,and VAS score was lower.Conclusions:Both sufentanil and remifentanil drugs can be good applied in pediatric tonsillectomy surgery.Sufentanil shows more advantages in improving the recovery quality and security of anesthesia after surgery.
Objective:To observe the analgesic and sedative effects of sufentanil and remifentanil during and after pediatric tonsillectomy and adenoidectomy surgery.Methods:One hundred patients involved in selective operation were chosen and divided into two groups randomly:sufentanil group (S group,n=50) and remifentanil group (R group,n=50).Patients in S group were rapidly induced by 0.2 μg/kg sufentanil,and were maintained with 0.2 μg·kg-1·h-1 in the operation.Sufentanil was withdrawn 30 min before the operation completed.Patients in R group were rapidly induced by 2 μg/kg remifentanil,and were maintained with 6 μg·kg-1·h-1 in the operation.Remifentanil was withdrawn 5 min before the operation completed.The hemodynamic indexes during and after the operation as well as the postoperative sedative degree of patients in the two groups were respectively observed.Results:No significant difference of hemodynamic indexes during the operation was observed between the two groups (P>0.05).No obvious difference was shown between the mean arterial pressure 5 min after removing tube in S group and the basic values;and a statistical difference was shown in R group (P<0.01).The Ramsay score of children in S group after operation was more appropriate,and VAS score was lower.Conclusions:Both sufentanil and remifentanil drugs can be good applied in pediatric tonsillectomy surgery.Sufentanil shows more advantages in improving the recovery quality and security of anesthesia after surgery.
2010, 35(9): 899-900.
Abstract:
Objective:To explore the reason of misdiagnosis of acute lymphatic leukemia as rheumatic diseases and reduce the misdiagnosis.Methods:Analyse the clinical manifestation and laboratory findings of 7 cases in acute lymphatic leukemia transfer from department of rheumatology.Results:The primary symptoms of 7 patients infected with acute lymphatic leukemia were musculoskeletal pain.Then the diagnosis was made from 1 month to 12 months after symptom occurring.The seven misdiagnosis patients included:seronegative spondylarthritis 4 cases,connective tissue disease 1 case,juvenile spondylarthritis 1 case,and rheumatoid arthritis 1 case.Conclusions:To reduce the misdiagnosis,a bone-marrow examination should be done before steroid treatment for the patients with musculoskeletal pain.
Objective:To explore the reason of misdiagnosis of acute lymphatic leukemia as rheumatic diseases and reduce the misdiagnosis.Methods:Analyse the clinical manifestation and laboratory findings of 7 cases in acute lymphatic leukemia transfer from department of rheumatology.Results:The primary symptoms of 7 patients infected with acute lymphatic leukemia were musculoskeletal pain.Then the diagnosis was made from 1 month to 12 months after symptom occurring.The seven misdiagnosis patients included:seronegative spondylarthritis 4 cases,connective tissue disease 1 case,juvenile spondylarthritis 1 case,and rheumatoid arthritis 1 case.Conclusions:To reduce the misdiagnosis,a bone-marrow examination should be done before steroid treatment for the patients with musculoskeletal pain.
2010, 35(9): 901-903.
Abstract:
Objective:To investigate the early onset of severe preeclampsia and maternal child treatment outcome.Methods:Forty-three patients with early onset severe preeclampsia patients were generally treated according to the condition of patients,looking forward to treatment and termination of pregnancy.Analysis of different treatment regimens mother child outcomes.Results:The gestational age > 32 weeks of neonatal and perinatal mortality of children was obviously lower than 32 weeks before the termination of pregnancy (P<0.01).Conclusions:Nearly 34 weeks gestation and early onset severe preeclampsia,pregnancy can be terminated by promoting the maturity of fetal lung.32 weeks of pregnancy before the early onset severe preeclampsia,mother's complications was not increasing with prolonged gestational ages under strict monitor.
Objective:To investigate the early onset of severe preeclampsia and maternal child treatment outcome.Methods:Forty-three patients with early onset severe preeclampsia patients were generally treated according to the condition of patients,looking forward to treatment and termination of pregnancy.Analysis of different treatment regimens mother child outcomes.Results:The gestational age > 32 weeks of neonatal and perinatal mortality of children was obviously lower than 32 weeks before the termination of pregnancy (P<0.01).Conclusions:Nearly 34 weeks gestation and early onset severe preeclampsia,pregnancy can be terminated by promoting the maturity of fetal lung.32 weeks of pregnancy before the early onset severe preeclampsia,mother's complications was not increasing with prolonged gestational ages under strict monitor.
2010, 35(9): 903-904.
Abstract:
Objective:To investigate the mortality and prognostic factors of multiple trauma patients.Methods:The clinical data of all 113 patients with multiple trauma admitted to our ICU were retrospectively analyzed.Results:Eighty of 113 multiple trauma patients survived,while 33 of them died.The mortality of all was 29.2%.The morbidity of multiple organ dysfunction syndrome (MODS) among all 113 patients was 38.1%,and the mortality was 58.1%.Compared with survived and died groups,There were statistical differences about hospitalization days,SIRS score,amount of blood transfused during resuscitation,APACHE Ⅱ score,MODS and shock.Conclusions:The mortality of multiple trauma is very high,the prognostic factors that affected the mortality are hospitalization days,APACHEⅡ score,MODS,shock,SIRS score and amount of blood transfusion.Protection against the prognostic factors can reduce the mortality.
Objective:To investigate the mortality and prognostic factors of multiple trauma patients.Methods:The clinical data of all 113 patients with multiple trauma admitted to our ICU were retrospectively analyzed.Results:Eighty of 113 multiple trauma patients survived,while 33 of them died.The mortality of all was 29.2%.The morbidity of multiple organ dysfunction syndrome (MODS) among all 113 patients was 38.1%,and the mortality was 58.1%.Compared with survived and died groups,There were statistical differences about hospitalization days,SIRS score,amount of blood transfused during resuscitation,APACHE Ⅱ score,MODS and shock.Conclusions:The mortality of multiple trauma is very high,the prognostic factors that affected the mortality are hospitalization days,APACHEⅡ score,MODS,shock,SIRS score and amount of blood transfusion.Protection against the prognostic factors can reduce the mortality.
2010, 35(9): 905-907.
Abstract:
Objective:To investigate the expressions and clinical significance of erythropoietin-producing human hepatocelluar A2 (EphA2) and E-cadherin in bladder urothelium carcinoma (BTCC).Methods:The expressions of EphA2 and E-cadherin proteins were detected by immunohistochemisty in 50 cases of BTCC and 10 cases of normal bladder mucosa.Results:The expression of EphA2 was negative and the E-cadherin expression was normal in all the 10 normal bladder mucosa.Abnormal EphA2 and E-cadherins expressions were found in 40 and 28 cases of BTCC (80.0%,56.0%).Abnormal EphA2 expression was positively related to the grade and the stage of BTCC (P<0.05),but negatively related to lymph node metastasis (P>0.05).Abnormal E-cadherin expression was negatively correlated to the grade,stage (P<0.05) and lymph node metastasis (P=0.008).The expression of EphA2 was inversely correlated with that of E-cadherin in BTCC (P<0.05).Conclusions:The expressions of EphA2 and E-cadherin are closely related to the biological behavior of BTCC.Detection of EphA2 and E-cadherin in BTCC may have prognostic value for the degree of malignancy.
Objective:To investigate the expressions and clinical significance of erythropoietin-producing human hepatocelluar A2 (EphA2) and E-cadherin in bladder urothelium carcinoma (BTCC).Methods:The expressions of EphA2 and E-cadherin proteins were detected by immunohistochemisty in 50 cases of BTCC and 10 cases of normal bladder mucosa.Results:The expression of EphA2 was negative and the E-cadherin expression was normal in all the 10 normal bladder mucosa.Abnormal EphA2 and E-cadherins expressions were found in 40 and 28 cases of BTCC (80.0%,56.0%).Abnormal EphA2 expression was positively related to the grade and the stage of BTCC (P<0.05),but negatively related to lymph node metastasis (P>0.05).Abnormal E-cadherin expression was negatively correlated to the grade,stage (P<0.05) and lymph node metastasis (P=0.008).The expression of EphA2 was inversely correlated with that of E-cadherin in BTCC (P<0.05).Conclusions:The expressions of EphA2 and E-cadherin are closely related to the biological behavior of BTCC.Detection of EphA2 and E-cadherin in BTCC may have prognostic value for the degree of malignancy.
2010, 35(9): 908-910.
Abstract:
Objective:To investigate the cause,clinic character and treatment,and to summarize the experiences for dealing with the reoperation of biliary tract.Methods:The clinical data of 228 patients admitted to our hospital who underwent reoperation of biliary tract were retrospectively analyzed.Results:The main cause of the reoperation was the residual or recurrent stones in the biliary tract (about 74.1% of the patients).Other cause including injury of the biliary tract,anastomotic stoma stricture and miss-diagnosed tumor.The treatments included hepatectomy,biliary-intestinal anastomosis and T-tube drainage.Conclusions:Disorders of the biliary tract account for the high possibility of the reoperation.The medical errors can also lead to reoperation of the biliary tract.Thoroughly examinations and systematic analysis preoperatively,carefully exploration and choosing suitable methods during the operation will greatly reduce the repeated operations.
Objective:To investigate the cause,clinic character and treatment,and to summarize the experiences for dealing with the reoperation of biliary tract.Methods:The clinical data of 228 patients admitted to our hospital who underwent reoperation of biliary tract were retrospectively analyzed.Results:The main cause of the reoperation was the residual or recurrent stones in the biliary tract (about 74.1% of the patients).Other cause including injury of the biliary tract,anastomotic stoma stricture and miss-diagnosed tumor.The treatments included hepatectomy,biliary-intestinal anastomosis and T-tube drainage.Conclusions:Disorders of the biliary tract account for the high possibility of the reoperation.The medical errors can also lead to reoperation of the biliary tract.Thoroughly examinations and systematic analysis preoperatively,carefully exploration and choosing suitable methods during the operation will greatly reduce the repeated operations.
2010, 35(9): 910-911.
Abstract:
Objective:To investigate the surgical procedures for treatment of ectopic pregnancy.Methods:Two hundred thirty nine cases of ectopic pregnancy were randomly divided into laparotomy group (107 cases) and laparoscopic surgery group (132 cases).Eighty-eight cases in the laparoscopic surgery group received laparoscopic salpingectomy,31 cases laparoscopic tubal incision surgery to take out the embryos from the oviduct and were injected MTX after the operation,9 cases underwent laparoscopic exploration plus curettage,and 4 cases resorted to laparotomy.Results:The operation time for laparoscopic surgery was much less than that for laparotomy (P<0.01),and the incidence of absorption fever or abdominal distension was less in the laparoscopic group,and the hospital stay after surgery was shorter in the laparoscopic group (P<0.01).Conclusions:Laparoscopic surgery has the advantages of minimal invasion and rapid recovery,which promises to be the main surgical method for treatment of ectopic pregnancy in the future.
Objective:To investigate the surgical procedures for treatment of ectopic pregnancy.Methods:Two hundred thirty nine cases of ectopic pregnancy were randomly divided into laparotomy group (107 cases) and laparoscopic surgery group (132 cases).Eighty-eight cases in the laparoscopic surgery group received laparoscopic salpingectomy,31 cases laparoscopic tubal incision surgery to take out the embryos from the oviduct and were injected MTX after the operation,9 cases underwent laparoscopic exploration plus curettage,and 4 cases resorted to laparotomy.Results:The operation time for laparoscopic surgery was much less than that for laparotomy (P<0.01),and the incidence of absorption fever or abdominal distension was less in the laparoscopic group,and the hospital stay after surgery was shorter in the laparoscopic group (P<0.01).Conclusions:Laparoscopic surgery has the advantages of minimal invasion and rapid recovery,which promises to be the main surgical method for treatment of ectopic pregnancy in the future.
2010, 35(9): 912-913.
Abstract:
Objective:To explore the clinical values of total resection of lesser curvature in the radical treatment of distal gastric carcinoma.Methods:A retrospective review was performed in 32 patients of distal advanced gastric carcinoma undergoing total resection of lesser curvature.Analyzing the postoperative complications,survival rates after operation,and the tumor invasion in resection margin of lesser curvature.Results:No one died in the 32 case of total resection of lesser curvature.The remain tumor invasion in resection margin of total resection of lesser curvature is 15.6% (5/32).The tumor invasion in lymph nodes of No1 is 21.9%.One,two and three year survival rates after operation were 90.6% and 78.1% and 65.6%,respectively.Conclusions:The total resection of lesser curvature performed in radical surgery of distal gastric carcinoma can decrease tumor recurrence,prevent tumor invasion in resection margin,increase the resection rate,and prolong the survivals after operation.
Objective:To explore the clinical values of total resection of lesser curvature in the radical treatment of distal gastric carcinoma.Methods:A retrospective review was performed in 32 patients of distal advanced gastric carcinoma undergoing total resection of lesser curvature.Analyzing the postoperative complications,survival rates after operation,and the tumor invasion in resection margin of lesser curvature.Results:No one died in the 32 case of total resection of lesser curvature.The remain tumor invasion in resection margin of total resection of lesser curvature is 15.6% (5/32).The tumor invasion in lymph nodes of No1 is 21.9%.One,two and three year survival rates after operation were 90.6% and 78.1% and 65.6%,respectively.Conclusions:The total resection of lesser curvature performed in radical surgery of distal gastric carcinoma can decrease tumor recurrence,prevent tumor invasion in resection margin,increase the resection rate,and prolong the survivals after operation.
2010, 35(9): 914-916.
Abstract:
Objective:To explore the effect of candesartan on ventricular remodeling and cardiac function in coronary heart disease patients with chronic heart failure.Methods:One hundred coronary heart disease patients with chronic heart failure were randomly divided into two groups,including treatment group and control group.All the patients were basically treated with cardiotonic,diuretic,phlebectasis medicine.The patients in control group were additionally treated with captopril (from low dose to target dose) for 12 months,and the patients in treatment group were additionally treated with candesartan (from low dose to target dose) for 12 months.All the patients were observed the changes of therapy,such as left ventricular ejection fraction,left ventricular end-diastolic dimension,left ventricular end-systolic dimension,interventricular septal thickness,left ventricular posterior wall thickness and cardiothoracic ratio.Results:Both the control group and the treatment group showed significant improvement in ventricular remodeling and cardiac function (P<0.01),whereas there was no statistical difference in ventricular remodeling and cardiac function detected between two groups (P>0.05).Conclusions:Candesartan showed the same favorable effects as Captopril on ventricular remodeling and cardiac function in chronic heart failure patient with coronary heart disease.
Objective:To explore the effect of candesartan on ventricular remodeling and cardiac function in coronary heart disease patients with chronic heart failure.Methods:One hundred coronary heart disease patients with chronic heart failure were randomly divided into two groups,including treatment group and control group.All the patients were basically treated with cardiotonic,diuretic,phlebectasis medicine.The patients in control group were additionally treated with captopril (from low dose to target dose) for 12 months,and the patients in treatment group were additionally treated with candesartan (from low dose to target dose) for 12 months.All the patients were observed the changes of therapy,such as left ventricular ejection fraction,left ventricular end-diastolic dimension,left ventricular end-systolic dimension,interventricular septal thickness,left ventricular posterior wall thickness and cardiothoracic ratio.Results:Both the control group and the treatment group showed significant improvement in ventricular remodeling and cardiac function (P<0.01),whereas there was no statistical difference in ventricular remodeling and cardiac function detected between two groups (P>0.05).Conclusions:Candesartan showed the same favorable effects as Captopril on ventricular remodeling and cardiac function in chronic heart failure patient with coronary heart disease.
Observation of the efficacy of total mesorectal excision in the middle and low rectal cancer surgery
2010, 35(9): 916-918.
Abstract:
Objective:To evaluate the efficacy of total mesorectal excision (TME) in the middle and low rectal cancer surgery.Methods:Forty-three cases of rectal cancer,tumor from the anal margin were less than 10 cm.Among these 43 cases,21 cases were application in traditional surgical treatment (traditional group) and 22 cases with application in TME treatment (TME group).For these patients in the two groups,the average operative time,intraoperative blood loss,hospitalization days,anastomotic leakage,urination,sexual function and local recurrence rate were compared.Results:In TME group,the average operation time,average blood loss,local recurrence rate,urinary dysfunction,and sexual dysfunction were statistical significances in contrast to in traditional group (P<0.05 to P<0.01).While the hospitalization days,anastomotic leakage and one year survival rate had no statistical significance (P>0.05).Conclusions:TME has so many advantages with short surgery time,less bleeding,fewer complications and low local recurrence rate,it is one of the best treatment for middle and low rectal cancer therapy.
Objective:To evaluate the efficacy of total mesorectal excision (TME) in the middle and low rectal cancer surgery.Methods:Forty-three cases of rectal cancer,tumor from the anal margin were less than 10 cm.Among these 43 cases,21 cases were application in traditional surgical treatment (traditional group) and 22 cases with application in TME treatment (TME group).For these patients in the two groups,the average operative time,intraoperative blood loss,hospitalization days,anastomotic leakage,urination,sexual function and local recurrence rate were compared.Results:In TME group,the average operation time,average blood loss,local recurrence rate,urinary dysfunction,and sexual dysfunction were statistical significances in contrast to in traditional group (P<0.05 to P<0.01).While the hospitalization days,anastomotic leakage and one year survival rate had no statistical significance (P>0.05).Conclusions:TME has so many advantages with short surgery time,less bleeding,fewer complications and low local recurrence rate,it is one of the best treatment for middle and low rectal cancer therapy.
2010, 35(9): 919-920.
Abstract:
Objective:To explore the treatment of anastomotic leakage after surgical operation for sophageal cancer and cardia cancer.Methods:Twenty-one of them received double-tube full drainage,empyema control,treatment for respiratory failure,nutritional support and other conservative therapies;4 of them underwent a second thoracotomy and catheter drainage for abscess cleaning,and 1 of them received a second thoracotomy and re-anastomosis in the neck after resection of the original anastomosis;7 cases were placed titanium-nickel-memory alloy covered esophageal stent,3 of whom had undergone a second thoracotomy and catheter drainage.Results:Twenty-one cases were cured;the postoperative hospital stay was 26 to 73 days,including 3 patients who had received a second thoracotomy,catheter drainage and esophageal stent implantation.Five died.The causes of death were respiratory failure and toxic shock due to uncontrolled infection.Conclusions:Proper selection and improved procedures can improve the clinical efficacy on intrathoracic anastomotic leakage.The procedure of secondary thoracotomy tube drainage and esophageal stent placement is worth investigating.
Objective:To explore the treatment of anastomotic leakage after surgical operation for sophageal cancer and cardia cancer.Methods:Twenty-one of them received double-tube full drainage,empyema control,treatment for respiratory failure,nutritional support and other conservative therapies;4 of them underwent a second thoracotomy and catheter drainage for abscess cleaning,and 1 of them received a second thoracotomy and re-anastomosis in the neck after resection of the original anastomosis;7 cases were placed titanium-nickel-memory alloy covered esophageal stent,3 of whom had undergone a second thoracotomy and catheter drainage.Results:Twenty-one cases were cured;the postoperative hospital stay was 26 to 73 days,including 3 patients who had received a second thoracotomy,catheter drainage and esophageal stent implantation.Five died.The causes of death were respiratory failure and toxic shock due to uncontrolled infection.Conclusions:Proper selection and improved procedures can improve the clinical efficacy on intrathoracic anastomotic leakage.The procedure of secondary thoracotomy tube drainage and esophageal stent placement is worth investigating.
2010, 35(9): 921-923.
Abstract:
Objective:To investigate the clinical significance of serum cyclooxygenase-2 (COX-2) and dinoprostone concentrations variation in patients with chronic obstructive pulmonary disease (COPD) during the acute exacerbation and the stable period.Methods:Enzyme-linked immunosorbent assay was used to measure the serum concentrations of COX-2 and dinoprostone in 53 health controls and 48 patients with COPD during the acute exacerbation and the stable period.Meanwhile the serum concentration of C-reactive protein was measured in patients with COPD during the acute exacerbation.Results:The serum concentrations of COX-2 and dinoprostone in patients with COPD during the acute exacerbation and the stable period were both significantly higher than those of the control (P<0.01).The serum concentration of dinoprostone during the acute exacerbation was significantly higher than that in the stable period (P<0.01),while COX-2 did not differ significantly in the two groups;during the acute exacerbation,the serum concentrations of COX-2 and dinoprostone showed positive correlation with the concentration of C-reactive protein (P<0.01 and P<0.05),and there was also a positive correlation between COX-2 and dinoprostone concentrations (P<0.01).Conclusions:COX-2 and dinoprostone are both involved in the inflammation activity.The serum concentration of dinoprostone may help to determine the condition of COPD during the acute exacerbation.
Objective:To investigate the clinical significance of serum cyclooxygenase-2 (COX-2) and dinoprostone concentrations variation in patients with chronic obstructive pulmonary disease (COPD) during the acute exacerbation and the stable period.Methods:Enzyme-linked immunosorbent assay was used to measure the serum concentrations of COX-2 and dinoprostone in 53 health controls and 48 patients with COPD during the acute exacerbation and the stable period.Meanwhile the serum concentration of C-reactive protein was measured in patients with COPD during the acute exacerbation.Results:The serum concentrations of COX-2 and dinoprostone in patients with COPD during the acute exacerbation and the stable period were both significantly higher than those of the control (P<0.01).The serum concentration of dinoprostone during the acute exacerbation was significantly higher than that in the stable period (P<0.01),while COX-2 did not differ significantly in the two groups;during the acute exacerbation,the serum concentrations of COX-2 and dinoprostone showed positive correlation with the concentration of C-reactive protein (P<0.01 and P<0.05),and there was also a positive correlation between COX-2 and dinoprostone concentrations (P<0.01).Conclusions:COX-2 and dinoprostone are both involved in the inflammation activity.The serum concentration of dinoprostone may help to determine the condition of COPD during the acute exacerbation.
2010, 35(9): 923-924.
Abstract:
Objective:To observe the clinical therapeutic effect and safety of asarone and Vitamin K1 combination as an assistant treatment on infants with asthmatic pneumonia.Methods:One hundred and thirty-eight patients aged from 2 months to 2 years were randomly divided into treatment group (69 cases) and control group (69 cases).The standard therapy was anti-inflammation,antitussive and elimating sputum treatment in these two groups.The treatment group was cured more with the combination of asarone and Vitamin K1.Results:There had the statistical significance both on the efficiency and the extinction time between these two groups (P<0.05 to P<0.01).Conclusions:Asarone and Vitamin K1 combination has obvious effects both on reducing bronchial spasm and respiratory tract secretion discharge,presenting side-effects happening.It is worth popularizing.
Objective:To observe the clinical therapeutic effect and safety of asarone and Vitamin K1 combination as an assistant treatment on infants with asthmatic pneumonia.Methods:One hundred and thirty-eight patients aged from 2 months to 2 years were randomly divided into treatment group (69 cases) and control group (69 cases).The standard therapy was anti-inflammation,antitussive and elimating sputum treatment in these two groups.The treatment group was cured more with the combination of asarone and Vitamin K1.Results:There had the statistical significance both on the efficiency and the extinction time between these two groups (P<0.05 to P<0.01).Conclusions:Asarone and Vitamin K1 combination has obvious effects both on reducing bronchial spasm and respiratory tract secretion discharge,presenting side-effects happening.It is worth popularizing.
2010, 35(9): 925-926.
Abstract:
Objective:To evaluate the effect of complex treatment of eye alkali burn.Methods:Twenty-two cases (34 eyes) of alkali burn were treated as follows:washing the conjunctival sac,cleaning ocular foreign bodies.Applying to local and general body more antibiotics,Vitamin C and corticosteroid,added with local heparinizing,auto-blood transfusion and other comprehensive therapy to promote healing.Results:Fifteen eyes got 0.8 or better vision after treatment,the corneal was translucent.One eye's vision was improved to 0.6,15 eyes to 0.25-0.4.These all eyes had corneal nebula or macula.Vision was above 0.1 in 2 eyes and the last 1 eye got light perception,all of these eyes had corneal leucoma,neovascularization,symblepharon and conjunctival sac constriction.Conclusions:After the effective comprehensive treatment,the alkali burn eyes can get a better result,and offer a good base for operation.
Objective:To evaluate the effect of complex treatment of eye alkali burn.Methods:Twenty-two cases (34 eyes) of alkali burn were treated as follows:washing the conjunctival sac,cleaning ocular foreign bodies.Applying to local and general body more antibiotics,Vitamin C and corticosteroid,added with local heparinizing,auto-blood transfusion and other comprehensive therapy to promote healing.Results:Fifteen eyes got 0.8 or better vision after treatment,the corneal was translucent.One eye's vision was improved to 0.6,15 eyes to 0.25-0.4.These all eyes had corneal nebula or macula.Vision was above 0.1 in 2 eyes and the last 1 eye got light perception,all of these eyes had corneal leucoma,neovascularization,symblepharon and conjunctival sac constriction.Conclusions:After the effective comprehensive treatment,the alkali burn eyes can get a better result,and offer a good base for operation.
2010, 35(9): 943-944.
Abstract:
Objective:To discuss the treatment of avoiding the different item's cross-contamination of automatic biochemical analyzer.Methods:There were divided into five groups:group A:the contents of alkaline phosphatase (ALP) in patients' serum with quality control serum were verified,then Mg2+ (magnesia ion) was verified;group B:firstly amylase (AMY) then Mg2+ were verified;matched group:just assess Mg2+;group C:the deionizer water was considered as sample,firstly assess the content of ALP in deionizer water,then assess Mg2+ ten times,afterward do the same processes which using quality control serum instead of deionizer water;group D:Use AMY instead of ALP,and do above-mentioned procedure.Results:Group A and group B the pollution rate were 9.93% and 10.13%.The cross-contamination was happened in assessment of Mg2+ as affected by reagent ALP and AMY.Conclusions:Medical technologists must be familiar with the manipulation and function of machines.When arranging the order of machines' testing items,it is needed to separate these items which has cross-contamination as far as possible.With the specific order,chemical pollution in different reagents can be reduced.
Objective:To discuss the treatment of avoiding the different item's cross-contamination of automatic biochemical analyzer.Methods:There were divided into five groups:group A:the contents of alkaline phosphatase (ALP) in patients' serum with quality control serum were verified,then Mg2+ (magnesia ion) was verified;group B:firstly amylase (AMY) then Mg2+ were verified;matched group:just assess Mg2+;group C:the deionizer water was considered as sample,firstly assess the content of ALP in deionizer water,then assess Mg2+ ten times,afterward do the same processes which using quality control serum instead of deionizer water;group D:Use AMY instead of ALP,and do above-mentioned procedure.Results:Group A and group B the pollution rate were 9.93% and 10.13%.The cross-contamination was happened in assessment of Mg2+ as affected by reagent ALP and AMY.Conclusions:Medical technologists must be familiar with the manipulation and function of machines.When arranging the order of machines' testing items,it is needed to separate these items which has cross-contamination as far as possible.With the specific order,chemical pollution in different reagents can be reduced.
2010, 35(9): 945-947.
Abstract:
Objective:To research the relationship between the platelet parameters including the changes of BPC,MPV,PDW,PCT and the vascular pathological changes of patients with type 2 diabetes mellitus (T2DM).Methods:The BPC,MPV,PDW and PCT were measured by the automatic blood cell analyzer in 120 patients with T2DM and 80 healthy people and the FPG was studied by the automatic biochemistry analyzer.Results:In contrast to healthy team,the level of FPG was higher (P<0.01),BPC was lower (P<0.01),MPV and PDW were higher (P<0.01),but PCT was no statistical difference (P>0.05) in T2DM team.To contrast every parameters between the vascular pathological changes team and non-vascular pathological changes team in patients with T2DM,FPG was no difference (P>0.05),but BPC in vascular pathological changes team was lower than the other one (P<0.01),MPV and PDW were higher than the other one (P<0.01),PCT was no difference (P>0.05).Conclusions:Dynamic monitoring BPC,MPV,and PDW changes had certain values to study the vascular pathological changes of T2DM.
Objective:To research the relationship between the platelet parameters including the changes of BPC,MPV,PDW,PCT and the vascular pathological changes of patients with type 2 diabetes mellitus (T2DM).Methods:The BPC,MPV,PDW and PCT were measured by the automatic blood cell analyzer in 120 patients with T2DM and 80 healthy people and the FPG was studied by the automatic biochemistry analyzer.Results:In contrast to healthy team,the level of FPG was higher (P<0.01),BPC was lower (P<0.01),MPV and PDW were higher (P<0.01),but PCT was no statistical difference (P>0.05) in T2DM team.To contrast every parameters between the vascular pathological changes team and non-vascular pathological changes team in patients with T2DM,FPG was no difference (P>0.05),but BPC in vascular pathological changes team was lower than the other one (P<0.01),MPV and PDW were higher than the other one (P<0.01),PCT was no difference (P>0.05).Conclusions:Dynamic monitoring BPC,MPV,and PDW changes had certain values to study the vascular pathological changes of T2DM.
2010, 35(9): 948-949.
Abstract:
Objective:To explore the effect and nursing skills of the moderate hypothermia machine on reducing higher fever in children.Methods:Using periodic review way,from June to September of 2008,15 cases of patients with higher fever were treated as control group,and from June to September of 2009,15 cases of patients with higher fever were treated as study group.The control group was treated by traditional method,while the study group was treated by moderate hypothermia machine and with extra nursing and observation.Results:The treatment effect of the study group was significant better than the control group (P<0.05).Conclusions:Moderate hypothermia machine has an obvious and persistent effects on reducing higher fever,and brain oxygen consumption,protecting brain cells and improving the quality of nursing.
Objective:To explore the effect and nursing skills of the moderate hypothermia machine on reducing higher fever in children.Methods:Using periodic review way,from June to September of 2008,15 cases of patients with higher fever were treated as control group,and from June to September of 2009,15 cases of patients with higher fever were treated as study group.The control group was treated by traditional method,while the study group was treated by moderate hypothermia machine and with extra nursing and observation.Results:The treatment effect of the study group was significant better than the control group (P<0.05).Conclusions:Moderate hypothermia machine has an obvious and persistent effects on reducing higher fever,and brain oxygen consumption,protecting brain cells and improving the quality of nursing.
2010, 35(9): 950-951.
Abstract:
Objective:To observe the efficacy of comfeel transparent dressing on patients with pressure sore complicated with scald.Methods:Fifty-two patients with pressure sore including 4 cases complicated with burns were randomly divided into two groups.Twenty four cases of pressure sore and two cases of burns in the study group were treated by comfeel,and the cases in the control group were managed by routine therapy.Comprehensive nursing was applied according to the patients' condition.Results:The recovery time was (4.21±1.52) days in the study group,and (10.84±3.12) days in the control group.The difference was significant between the two groups (P<0.01).The effective rate was 100% in the study group,which was superior to the 88.5% in the control group (P<0.05).Conclusions:Comfeel may achieve satisfactory outcome in treatment of pressure sore and burns with the advantages of less curing time and higher efficiency.
Objective:To observe the efficacy of comfeel transparent dressing on patients with pressure sore complicated with scald.Methods:Fifty-two patients with pressure sore including 4 cases complicated with burns were randomly divided into two groups.Twenty four cases of pressure sore and two cases of burns in the study group were treated by comfeel,and the cases in the control group were managed by routine therapy.Comprehensive nursing was applied according to the patients' condition.Results:The recovery time was (4.21±1.52) days in the study group,and (10.84±3.12) days in the control group.The difference was significant between the two groups (P<0.01).The effective rate was 100% in the study group,which was superior to the 88.5% in the control group (P<0.05).Conclusions:Comfeel may achieve satisfactory outcome in treatment of pressure sore and burns with the advantages of less curing time and higher efficiency.
2010, 35(9): 952-954.
Abstract:
Objective:To assess the effect of psychological intervene on anxiety and activities of daily living (ADL) for the patients suffering from facture.Methods:It was a randomized controlled trial.Eighty patients with hip facture,aged above 80 years old,were randomized to receive psychological rehabilitation or not in addition to the same preoperative preparative,operation and postoperative rehabilitation.Results:The anxiety in psychological rehabilitation group is significantly improved than control group (P<0.05).Significantly greater gains were seen in Barthel Index of ADL for the psychological rehabilitation group 4 months after operation (P<0.05).Conclusions:Data suggest that peri-operative psychotherapy benefits postoperative anxiety and ADL for the patients suffering from fracture.
Objective:To assess the effect of psychological intervene on anxiety and activities of daily living (ADL) for the patients suffering from facture.Methods:It was a randomized controlled trial.Eighty patients with hip facture,aged above 80 years old,were randomized to receive psychological rehabilitation or not in addition to the same preoperative preparative,operation and postoperative rehabilitation.Results:The anxiety in psychological rehabilitation group is significantly improved than control group (P<0.05).Significantly greater gains were seen in Barthel Index of ADL for the psychological rehabilitation group 4 months after operation (P<0.05).Conclusions:Data suggest that peri-operative psychotherapy benefits postoperative anxiety and ADL for the patients suffering from fracture.
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