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2011 Vol. 36, No. 11
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2011, 36(11): 1169-1173.
Abstract:
Objective:To investigate the protective effects of ethanol postconditioning on isolated rats' hearts, and discuss the antioxidative mechanism. Methods:Hearts isolated from male Sprague-Dawley rats were perfused on a langendorff apparatus and subjected to 30 minutes of regional ischemia(occlusion of left anterior descending artery) followed by 120 minutes of reperfusion. The ventricular hemodynamic parameters were measured. SOD activity and MDA content were detected to evaluate cell antioxidant ability. The expressions of aldehyde dehydrogenase 2,Bcl-2 and Bax at mRNA level of left anterior myocardium were detected by RT-PCR analysis. Results:Compared with ischemia-reperfusion group, ethanol postconditioning improved the recovery of left ventricular developed pressure,maximal rise/fall rate of left ventricular pressure(P<0.01),SOD activity was increased and the content of MDA was decreased,Bcl-2 mRNA expression was increased,while Bax mRNA expression was decreased. Administration of ALDH2 inhibitor CYA attenuated the effect of ethanol postconditioning,the recovery of hemodynamic parameters were inhibited(P<0.01),SOD activity was decreased and the content of MDA was increased,Bcl-2 mRNA expression was decreased,Bax mRNA expression was increased. Conclusions:The protective effect of ethanol postconditioning on isolated rats' hearts is related to upregulating mitochondrial ALDH2 mRNA expression,likely through its antioxidative role and reduction of myocardial apoptosis.
Objective:To investigate the protective effects of ethanol postconditioning on isolated rats' hearts, and discuss the antioxidative mechanism. Methods:Hearts isolated from male Sprague-Dawley rats were perfused on a langendorff apparatus and subjected to 30 minutes of regional ischemia(occlusion of left anterior descending artery) followed by 120 minutes of reperfusion. The ventricular hemodynamic parameters were measured. SOD activity and MDA content were detected to evaluate cell antioxidant ability. The expressions of aldehyde dehydrogenase 2,Bcl-2 and Bax at mRNA level of left anterior myocardium were detected by RT-PCR analysis. Results:Compared with ischemia-reperfusion group, ethanol postconditioning improved the recovery of left ventricular developed pressure,maximal rise/fall rate of left ventricular pressure(P<0.01),SOD activity was increased and the content of MDA was decreased,Bcl-2 mRNA expression was increased,while Bax mRNA expression was decreased. Administration of ALDH2 inhibitor CYA attenuated the effect of ethanol postconditioning,the recovery of hemodynamic parameters were inhibited(P<0.01),SOD activity was decreased and the content of MDA was increased,Bcl-2 mRNA expression was decreased,Bax mRNA expression was increased. Conclusions:The protective effect of ethanol postconditioning on isolated rats' hearts is related to upregulating mitochondrial ALDH2 mRNA expression,likely through its antioxidative role and reduction of myocardial apoptosis.
2011, 36(11): 1173-1176.
Abstract:
Objective:To establish a rapid detection method of mycobacterium tuberculosis. Methods:Multiplex polymerase chain reaction(PCR) was employed to dectect katG,IS1081,inhA and rpoB genes of mycobacterium tuberculosis. Forty-eight DNA samples were obtained from the national institute for the control of pharmaceutical and biological products (NICPBP), forty drug resistant mycobacterium tuberculosis were isolated and 40 drug sensitive mycobacterium tuberculosis were isolated from the culture-based bacterias and 46 from clinical samples. All results have been confirmed by sequencing. Results:These genes were successfully 1detected in all samples by multiplex PCR. Conclusions:Multiplex PCR can be used to detect target genes of mycobacterium tuberculosis rapidly.
Objective:To establish a rapid detection method of mycobacterium tuberculosis. Methods:Multiplex polymerase chain reaction(PCR) was employed to dectect katG,IS1081,inhA and rpoB genes of mycobacterium tuberculosis. Forty-eight DNA samples were obtained from the national institute for the control of pharmaceutical and biological products (NICPBP), forty drug resistant mycobacterium tuberculosis were isolated and 40 drug sensitive mycobacterium tuberculosis were isolated from the culture-based bacterias and 46 from clinical samples. All results have been confirmed by sequencing. Results:These genes were successfully 1detected in all samples by multiplex PCR. Conclusions:Multiplex PCR can be used to detect target genes of mycobacterium tuberculosis rapidly.
2011, 36(11): 1177-1181.
Abstract:
Objective:To investigate the effect of costimulatory signal 4-1BBL/4-1 BB in the activation of the T lymphocytes and the expression of costimulatory molecule of patients with (SLE). Methods:The peripheral blood mononuclear cells (PBMCs) were stimulated with anti-CD3 and the costimulatory signal of 4-1BBL/4-1BB was blocked by anti-4-1BBL. The expressions of 4-1BB, CD40L,4-1BBL,CD40 and CD69 of T cell and B cell before blocked and after blocked by anti-4-1BBL were detected by flow cytometry. Results:The expression of CD69 on T cells of SLE patients showed significant difference(P<0.01) with healthy controls. The expressions of 4-1BB,CD40L,4-1BBL and CD40 on the lymphocytes of SLE patients were significantly higher than that of normal control(P<0.01). There were obviously increased expression of 4-1BB and CD40L on the T lymphocytes stimulated by anti-CD3 antibody in SLE patients than healthy controls (P<0.01). With the anti-4-1BBL monoantibody blocked, there were decreased expression of 4-1BB CD40L (P<0.01). The expression of CD40 on B cell was significantly decreased, which is less than SLE unstimulted group and SLE stimulated group(P<0.05). Conclusions:T cell and B cell activation level of SLE patients were increased and 4-1BBL/4-1BB signals play a role in keeping the activation.
Objective:To investigate the effect of costimulatory signal 4-1BBL/4-1 BB in the activation of the T lymphocytes and the expression of costimulatory molecule of patients with (SLE). Methods:The peripheral blood mononuclear cells (PBMCs) were stimulated with anti-CD3 and the costimulatory signal of 4-1BBL/4-1BB was blocked by anti-4-1BBL. The expressions of 4-1BB, CD40L,4-1BBL,CD40 and CD69 of T cell and B cell before blocked and after blocked by anti-4-1BBL were detected by flow cytometry. Results:The expression of CD69 on T cells of SLE patients showed significant difference(P<0.01) with healthy controls. The expressions of 4-1BB,CD40L,4-1BBL and CD40 on the lymphocytes of SLE patients were significantly higher than that of normal control(P<0.01). There were obviously increased expression of 4-1BB and CD40L on the T lymphocytes stimulated by anti-CD3 antibody in SLE patients than healthy controls (P<0.01). With the anti-4-1BBL monoantibody blocked, there were decreased expression of 4-1BB CD40L (P<0.01). The expression of CD40 on B cell was significantly decreased, which is less than SLE unstimulted group and SLE stimulated group(P<0.05). Conclusions:T cell and B cell activation level of SLE patients were increased and 4-1BBL/4-1BB signals play a role in keeping the activation.
2011, 36(11): 1181-1183.
Abstract:
Objective:To explore the changes of pulmonary ventilation function(PVF) in obese rats with leptin resistance induced by high-fat diet. Methods:Thirty female Sprague-Dawley weaning rats were randomly divided into control group and high-fat diet group according to their body weight. Fifteen rats were fed with basic diet and 15 rats were fed with high-fat diet. At the end of the 8th week, 7 obese rats were selected by body weight from high-fat diet group as obese group with leptin resistance. The body weight,blood serum leptin concentration,tidal volume(TV),pulmonary ventilation(PV),forced vital capacity(FVC),maximal midexpiratary flow curve (MMEF),peak inspiratory flow(PIF) and peak expiratory flow(PEF) of all rats in two groups were detected. Results:The body weight from the 3rd week to the 8th week,blood serum leptin concentration,PV,PIF and PEF of obese group at the end of the 8th week were higher than those of control group(P<0.05-P<0.01). No significant difference of TV,FVC and MMEF were found between two groups at the end of 8th week. Conclusions:Obesity with leptin resistance induced by high-fat diet impairs the PVF of female rats.
Objective:To explore the changes of pulmonary ventilation function(PVF) in obese rats with leptin resistance induced by high-fat diet. Methods:Thirty female Sprague-Dawley weaning rats were randomly divided into control group and high-fat diet group according to their body weight. Fifteen rats were fed with basic diet and 15 rats were fed with high-fat diet. At the end of the 8th week, 7 obese rats were selected by body weight from high-fat diet group as obese group with leptin resistance. The body weight,blood serum leptin concentration,tidal volume(TV),pulmonary ventilation(PV),forced vital capacity(FVC),maximal midexpiratary flow curve (MMEF),peak inspiratory flow(PIF) and peak expiratory flow(PEF) of all rats in two groups were detected. Results:The body weight from the 3rd week to the 8th week,blood serum leptin concentration,PV,PIF and PEF of obese group at the end of the 8th week were higher than those of control group(P<0.05-P<0.01). No significant difference of TV,FVC and MMEF were found between two groups at the end of 8th week. Conclusions:Obesity with leptin resistance induced by high-fat diet impairs the PVF of female rats.
2011, 36(11): 1184-1186.
Abstract:
Objective:To detect frequency of and programmed cell death-1(PD-1) expression of CD4+CD25highTreg peripheral blood of systemic lupus erythematosus(SLE) patients and to explore their roles in immune disorder of SLE. Methods:Flow cytometry(FCM) was used to determine the frequencies of peripheral blood CD4+CD25highTreg and CD4+CD25lowT cells and the PD-1 expression on these cells in SLE patients and healthy normal controls. Results:The frequency of CD4+CD25highTreg among CD4+Treg in peripheral blood of SLE patients group(0.63±0.31)% decreased significantly(P<0.01),compared with normal control group(2.07±0.74)%. The PD-1 expression on CD4+CD25highTreg in SLE group(24.99±18.65)% was obviously higher than that in normal control groups(6.97±1.92)% (P<0.05). There were also was no significant differences in both the frequency of CD4+CD25lowT cells and the PD-1 expression on these subset cells among two groups(P<0.05). Conclusions:Decreased number of CD4+CD25highTreg and upregulated expression of PD-1 on these Treg may play an important role in the pathogenesis of SLE.
Objective:To detect frequency of and programmed cell death-1(PD-1) expression of CD4+CD25highTreg peripheral blood of systemic lupus erythematosus(SLE) patients and to explore their roles in immune disorder of SLE. Methods:Flow cytometry(FCM) was used to determine the frequencies of peripheral blood CD4+CD25highTreg and CD4+CD25lowT cells and the PD-1 expression on these cells in SLE patients and healthy normal controls. Results:The frequency of CD4+CD25highTreg among CD4+Treg in peripheral blood of SLE patients group(0.63±0.31)% decreased significantly(P<0.01),compared with normal control group(2.07±0.74)%. The PD-1 expression on CD4+CD25highTreg in SLE group(24.99±18.65)% was obviously higher than that in normal control groups(6.97±1.92)% (P<0.05). There were also was no significant differences in both the frequency of CD4+CD25lowT cells and the PD-1 expression on these subset cells among two groups(P<0.05). Conclusions:Decreased number of CD4+CD25highTreg and upregulated expression of PD-1 on these Treg may play an important role in the pathogenesis of SLE.
2011, 36(11): 1187-1189,1193.
Abstract:
Objective:To investigate the prognostic features of patients with epidemic cerebrospinal meningitis. Methods:The seasonal and age distribution, the clinical features and prognosis, and the complications of epidemic cerebrospinal meningitis were analyzed among 77 patients treated in our hospital. Results:The mean age of all cases was(23.96±18.21) years old. The main clinical features were as follows:fever,headache,conscious disturbance and petechia or ecchymosis of skins. In all 77 cases,55 cases were ordinary type,and 22 cases fulminant type. Four patients died in hospital and 6 patients were discharged from hospital without recovery. The factors associated with bad outcome were DIC, shock, cerebral hernia, respiratory failure or other organ function lesions. Neisseria meningitidis were found through bacteriologic culture in 13 cases,and some were identified as serogroup C. Conclusions:Multiple organ function lesion is a significant characteristic for epidemic cerebrospinal meningitis. The symptoms of the patients are usually heavier,and it maybe was correlated with vibration of bacterial community.
Objective:To investigate the prognostic features of patients with epidemic cerebrospinal meningitis. Methods:The seasonal and age distribution, the clinical features and prognosis, and the complications of epidemic cerebrospinal meningitis were analyzed among 77 patients treated in our hospital. Results:The mean age of all cases was(23.96±18.21) years old. The main clinical features were as follows:fever,headache,conscious disturbance and petechia or ecchymosis of skins. In all 77 cases,55 cases were ordinary type,and 22 cases fulminant type. Four patients died in hospital and 6 patients were discharged from hospital without recovery. The factors associated with bad outcome were DIC, shock, cerebral hernia, respiratory failure or other organ function lesions. Neisseria meningitidis were found through bacteriologic culture in 13 cases,and some were identified as serogroup C. Conclusions:Multiple organ function lesion is a significant characteristic for epidemic cerebrospinal meningitis. The symptoms of the patients are usually heavier,and it maybe was correlated with vibration of bacterial community.
2011, 36(11): 1190-1193.
Abstract:
Objective:To investigate the epidermal growth factor receptor(EGFR) mutation in plasma and urine samples of patients with advanced lung adenocarcinoma,and to analyze the feasibility of detecting EGFR mutataion in urine. Methods:The plasma and urine cell-free DNA (cfDNA) in 60 patients with advanced lung adenocarcinoma were extracted with modified phenol-chloroform method. Mutant-enriched PCR coupled sequencing of cfDNA was used to detect the EGFR mutation. Results:Among the 60 cases, EGFR mutation was detected in the plasma of 12 cases including 7 deletion mutation in exon 19 and 5 mutation in exon 21,while the result was negative in the urine samples. In the plasma samples,EGFR mutation was correlated with the gender of the patients but not with the age or smoking history. Conclusions:EGFR mutation can be detected in the plasma samples of patients with advanced lung adenocarcinoma but not in the urine samples.
Objective:To investigate the epidermal growth factor receptor(EGFR) mutation in plasma and urine samples of patients with advanced lung adenocarcinoma,and to analyze the feasibility of detecting EGFR mutataion in urine. Methods:The plasma and urine cell-free DNA (cfDNA) in 60 patients with advanced lung adenocarcinoma were extracted with modified phenol-chloroform method. Mutant-enriched PCR coupled sequencing of cfDNA was used to detect the EGFR mutation. Results:Among the 60 cases, EGFR mutation was detected in the plasma of 12 cases including 7 deletion mutation in exon 19 and 5 mutation in exon 21,while the result was negative in the urine samples. In the plasma samples,EGFR mutation was correlated with the gender of the patients but not with the age or smoking history. Conclusions:EGFR mutation can be detected in the plasma samples of patients with advanced lung adenocarcinoma but not in the urine samples.
2011, 36(11): 1194-1197,1200.
Abstract:
Objective:To study the expressions of CD147,Matrix metalloproteinase-9(MMP-9) and vascular endothelial growth factor (VEGF) in renal cell carcinoma(RCC),and explore their correlations with tumor growth,tumor invasion and metastasis. Methods:The expressions of CD147,MMP-9 and VEGF were detected by immunohistochemical SP method in tissue from the carcinoma(RCC,n=107) and normal renal tissue (n=10). The relationships between the expressions and clinical pathology were analyzed, and the correlations among CD147, MMP-9 and VEGF were studied. Results:The expressions of CD147, MMP-9 and VEGF in RCC were significantly higher than those in normal renal tissue(P<0.01),which had no statistical significance related to pathological type(P>0.05),but had statistical significances related to clinical staging(P<0.01). A positive correlation among CD147,MMP-9 and VEGF was observed(P<0.01). Furthermore,the expression of CD147 was statistical significance associated with tumor size,clinical stage and distant metastasis(P<0.01),but not with age and gender(P>0.05). Conclusions:CD147,MMP-9 and VEGF play the important role in the progression and invasion in RCC,the detection of CD147,MMP-9 and VEGF expressions may be the potential biological indexes which reflect tumor growth,invasion and metastasis of RCC.
Objective:To study the expressions of CD147,Matrix metalloproteinase-9(MMP-9) and vascular endothelial growth factor (VEGF) in renal cell carcinoma(RCC),and explore their correlations with tumor growth,tumor invasion and metastasis. Methods:The expressions of CD147,MMP-9 and VEGF were detected by immunohistochemical SP method in tissue from the carcinoma(RCC,n=107) and normal renal tissue (n=10). The relationships between the expressions and clinical pathology were analyzed, and the correlations among CD147, MMP-9 and VEGF were studied. Results:The expressions of CD147, MMP-9 and VEGF in RCC were significantly higher than those in normal renal tissue(P<0.01),which had no statistical significance related to pathological type(P>0.05),but had statistical significances related to clinical staging(P<0.01). A positive correlation among CD147,MMP-9 and VEGF was observed(P<0.01). Furthermore,the expression of CD147 was statistical significance associated with tumor size,clinical stage and distant metastasis(P<0.01),but not with age and gender(P>0.05). Conclusions:CD147,MMP-9 and VEGF play the important role in the progression and invasion in RCC,the detection of CD147,MMP-9 and VEGF expressions may be the potential biological indexes which reflect tumor growth,invasion and metastasis of RCC.
2011, 36(11): 1198-1200.
Abstract:
Objective:To observe the clinical effect of root canal disinfection with calcium hydroxide iodoform paste and compare the role with formaldehyde cresol formocresol. Methods:One hundred and twelve teeth which had the symptoms were chosen to do root canal treatment. These teeth were divided into observation group and control group. The teeth in each group were completed root canal treatment in 2 times. The teeth in observation group were disinfected using calcium hydroxide iodoform paste in root canals,while others in control group were disinfected using formaldehyde cresol formocresol cotton absorbents. The clinical effect was evaluated in the first subsequent consultation a week later. Results:One week after the root canal treatment,the currative effect in observation group was better than the control group(P<0.05). Conclusions:The clinical effect is obvious when root canal was disinfected with calcium hydroxide iodoform paste.
Objective:To observe the clinical effect of root canal disinfection with calcium hydroxide iodoform paste and compare the role with formaldehyde cresol formocresol. Methods:One hundred and twelve teeth which had the symptoms were chosen to do root canal treatment. These teeth were divided into observation group and control group. The teeth in each group were completed root canal treatment in 2 times. The teeth in observation group were disinfected using calcium hydroxide iodoform paste in root canals,while others in control group were disinfected using formaldehyde cresol formocresol cotton absorbents. The clinical effect was evaluated in the first subsequent consultation a week later. Results:One week after the root canal treatment,the currative effect in observation group was better than the control group(P<0.05). Conclusions:The clinical effect is obvious when root canal was disinfected with calcium hydroxide iodoform paste.
2011, 36(11): 1201-1203.
Abstract:
Objective:To study the distribution of peroneal artery of lateral post-clearance and vascular diameter and hemodynamic parameters by high-resolution color Doppler flow imaging(CDFI) provides a basis of the preoperative evaluation of vascular quality and the design of low-rotation point sural neurovascular flap. Methods:A total of 9 cases patients were collected for this study from December 2009 to March 2011,each case was detected the number of perforating branches of the peroneal artery,the beginning of diameter and hemodynamic parameters which the initial diameter is bigger than 0.5 mm and the range is 0 to 3 cm from the lateral tip, then mark the location of where it pierces the deep fascia and implement the operation of low-rotation point sural neurovascular flap graft. Results:Twenty-two perforating arteries were recorded,initial diameter of perforating arteries were (0.78±0.23) mm,the length of the piercing point from deep fascia to the lateral tip was(1.66±0.91) cm,the vascular flow peak systolic velocity was (0.19±0.03) m/s. The location of the perforating point from deep fascia and traveling direction were completly anastomosised with preoperative positioning of the body surface. All flaps survived completely. Conclusions:CDFI can show the distribution of peroneal artery of lateral post gap and vascular diameter and hemodynamic condition and can accurately locate the surface positioning,which can be used for preoperative evaluation of the quality of perforating branches of blood vessels and provide scientific basis for the design of low-rotation point of sural neurovascular flap.
Objective:To study the distribution of peroneal artery of lateral post-clearance and vascular diameter and hemodynamic parameters by high-resolution color Doppler flow imaging(CDFI) provides a basis of the preoperative evaluation of vascular quality and the design of low-rotation point sural neurovascular flap. Methods:A total of 9 cases patients were collected for this study from December 2009 to March 2011,each case was detected the number of perforating branches of the peroneal artery,the beginning of diameter and hemodynamic parameters which the initial diameter is bigger than 0.5 mm and the range is 0 to 3 cm from the lateral tip, then mark the location of where it pierces the deep fascia and implement the operation of low-rotation point sural neurovascular flap graft. Results:Twenty-two perforating arteries were recorded,initial diameter of perforating arteries were (0.78±0.23) mm,the length of the piercing point from deep fascia to the lateral tip was(1.66±0.91) cm,the vascular flow peak systolic velocity was (0.19±0.03) m/s. The location of the perforating point from deep fascia and traveling direction were completly anastomosised with preoperative positioning of the body surface. All flaps survived completely. Conclusions:CDFI can show the distribution of peroneal artery of lateral post gap and vascular diameter and hemodynamic condition and can accurately locate the surface positioning,which can be used for preoperative evaluation of the quality of perforating branches of blood vessels and provide scientific basis for the design of low-rotation point of sural neurovascular flap.
2011, 36(11): 1204-1206.
Abstract:
Objective:To summarize the clinical characteristics of chronic cough in children caused by upper airway cough syndrome (UACS). Methods:Forty-eight children diagnosed with UACS were given systematic treatment such as anti-inflammation,anti-allergy, anti-infection decongestants and so on,and the clinical data were collected and analyzed. Results:There were 26 misdiagnosed cases among the 48 cases. The misdiagnositic rate was 54.17%. After two-week reasonable and targeted treatment,the symptoms and signs in 42 cases were obviously relieved or disappeared. The effective rate was 87.50%. Conclusions:Chronic cough is the chief complaint of UACS associated with other complex symptoms,so it is easy to be misdiagnosed and mistreated. All the children with upper airway cough syndrome can be diagnosed through its detail history of disease,reasonable physical examination and specialist consultation. The targeted therapy can give satisfied effect to upper airway cough syndrome.
Objective:To summarize the clinical characteristics of chronic cough in children caused by upper airway cough syndrome (UACS). Methods:Forty-eight children diagnosed with UACS were given systematic treatment such as anti-inflammation,anti-allergy, anti-infection decongestants and so on,and the clinical data were collected and analyzed. Results:There were 26 misdiagnosed cases among the 48 cases. The misdiagnositic rate was 54.17%. After two-week reasonable and targeted treatment,the symptoms and signs in 42 cases were obviously relieved or disappeared. The effective rate was 87.50%. Conclusions:Chronic cough is the chief complaint of UACS associated with other complex symptoms,so it is easy to be misdiagnosed and mistreated. All the children with upper airway cough syndrome can be diagnosed through its detail history of disease,reasonable physical examination and specialist consultation. The targeted therapy can give satisfied effect to upper airway cough syndrome.
2011, 36(11): 1206-1207.
Abstract:
Objective:To investigate the clinical effect of laparoscopic reparation on peptic ulcer perforation. Methods:The clinical data of 74 cases were retrospectively reviewed from 2005 to 2010. Thirty-six cases were performed with laparoscopic repair(laparoscopic group) and 38 cases underwent open surgery(open surgery group). The mean blood loss,mean surgery time,recovery of the stomach and intestines function,hospital stay,hospital cost and the rate of complications were observed. Results:Compared with the open surgery group,the mean blood loss,mean surgery time,recovery of the stomach and intestines function,and hospital stay in laparoscopic group had statistically significant difference (P<0.01), the rate of complications in laparoscopic group had no statistically significant difference(P>0.05). Conclusions:The laparoscopic repair in patients with peptic ulcer perforation is safety and effective,so it is worth to recommend its clinical use.
Objective:To investigate the clinical effect of laparoscopic reparation on peptic ulcer perforation. Methods:The clinical data of 74 cases were retrospectively reviewed from 2005 to 2010. Thirty-six cases were performed with laparoscopic repair(laparoscopic group) and 38 cases underwent open surgery(open surgery group). The mean blood loss,mean surgery time,recovery of the stomach and intestines function,hospital stay,hospital cost and the rate of complications were observed. Results:Compared with the open surgery group,the mean blood loss,mean surgery time,recovery of the stomach and intestines function,and hospital stay in laparoscopic group had statistically significant difference (P<0.01), the rate of complications in laparoscopic group had no statistically significant difference(P>0.05). Conclusions:The laparoscopic repair in patients with peptic ulcer perforation is safety and effective,so it is worth to recommend its clinical use.
2011, 36(11): 1208-1209.
Abstract:
Objective:To investigate the clinical efficacy and safety of nimodiping on delayed cerebral vasospasm after traumatic subarachnoid hemorrhage(tSAH). Methods:Eighty patients with tSAH were randomly divided into nimodiping treatment group and control group. While the routine treatments of decreasing intracranial pressure,stopping bleeding,nutrition for nerve and so on,were used in two groups, the nimodiping was added through intravenous administration (1 mg/h) in treatment group. Two weeks later, nimodiping were continuously used through oral administration (30 mg tid) for 12-24 weeks. And then, the examination of color doppler were performed to observe hemodynamic changes of the middle cerebral artery at 24 hours,72 hours,the seventh,fourteenth day. Glasgow outcome scale after three months of the treatments was observed and analysed. Results:The levels of cerebral vasospasm and prognosis were significant difference between nimodiping treatment group and control group(P<0.05). Conclusions:Nimodiping can obviously prevent cerebral vasospasm and improve outcome of patient's after tSAH.
Objective:To investigate the clinical efficacy and safety of nimodiping on delayed cerebral vasospasm after traumatic subarachnoid hemorrhage(tSAH). Methods:Eighty patients with tSAH were randomly divided into nimodiping treatment group and control group. While the routine treatments of decreasing intracranial pressure,stopping bleeding,nutrition for nerve and so on,were used in two groups, the nimodiping was added through intravenous administration (1 mg/h) in treatment group. Two weeks later, nimodiping were continuously used through oral administration (30 mg tid) for 12-24 weeks. And then, the examination of color doppler were performed to observe hemodynamic changes of the middle cerebral artery at 24 hours,72 hours,the seventh,fourteenth day. Glasgow outcome scale after three months of the treatments was observed and analysed. Results:The levels of cerebral vasospasm and prognosis were significant difference between nimodiping treatment group and control group(P<0.05). Conclusions:Nimodiping can obviously prevent cerebral vasospasm and improve outcome of patient's after tSAH.
2011, 36(11): 1210-1212.
Abstract:
Objective:To discuss the clinical features,pathophysiology and treatment of diabetic ketoacidosis(DKA). Methods:All of 50 patients were treated with reasonable fluid infusion,small doses of insulin, improving electrolyte disturbances,and eliminating the inducing factors. Results:The level of blood glucose decreased and hyperlipoidemia was improved in 24 hours and the potassium, sodium and chlorine became normal in 48 hours in all of the patients with treatment. Carban dioxide-combining power was rised to normal in 2 to 3 days and the ketonebody was negative in 3 to 5 days in 40 patients. There were ten critical patients in all of the 50 patients. Carban dioxide-combining power became normal in one week and ketonebody was negative in 7 to 10 days in the 10 critical patients. Conclusions:Diabetic ketoacidosis was in rapidly progress and acucte onset. The key treatment to a successful rescue is enough fluid infusion at the very beginning stage and with timely diagosis.
Objective:To discuss the clinical features,pathophysiology and treatment of diabetic ketoacidosis(DKA). Methods:All of 50 patients were treated with reasonable fluid infusion,small doses of insulin, improving electrolyte disturbances,and eliminating the inducing factors. Results:The level of blood glucose decreased and hyperlipoidemia was improved in 24 hours and the potassium, sodium and chlorine became normal in 48 hours in all of the patients with treatment. Carban dioxide-combining power was rised to normal in 2 to 3 days and the ketonebody was negative in 3 to 5 days in 40 patients. There were ten critical patients in all of the 50 patients. Carban dioxide-combining power became normal in one week and ketonebody was negative in 7 to 10 days in the 10 critical patients. Conclusions:Diabetic ketoacidosis was in rapidly progress and acucte onset. The key treatment to a successful rescue is enough fluid infusion at the very beginning stage and with timely diagosis.
2011, 36(11): 1213-1214.
Abstract:
Objective:To summarize the experience in treating patients with paraquat poisoning. Methods:Twenty-one patients with paraquat poisoning were treated by comprehensive medical therapy(gastric lavage,catharsis,blood purification,medication and so on). Results:Five patients died,three left hospital without notice and thirteen recovered. Conclusions:The key to successful rescue include early gastric lavage,catharsis and blood purification.
Objective:To summarize the experience in treating patients with paraquat poisoning. Methods:Twenty-one patients with paraquat poisoning were treated by comprehensive medical therapy(gastric lavage,catharsis,blood purification,medication and so on). Results:Five patients died,three left hospital without notice and thirteen recovered. Conclusions:The key to successful rescue include early gastric lavage,catharsis and blood purification.
2011, 36(11): 1215-1217.
Abstract:
Objective:To investigate the safety and efficacy of the transurethral plasma kinetic resection of the patients with prostatic hyperplasia size. Methods:Forty-one patients with benign prostate hyperplasia were treated by transurethral bipolar plasmakinetic prostatectomy and their clinical data were retrospectively summarized. Results:The mean operation time was(82.5±9.2) minutes,and the mean blood loss was(195.5±65.8) ml. 3 cases were complicated with urethrostenosis,but no patient exhibited clinical sign of (transurethral resection syndrome. All cases were folowed up for 24 months,The Qmax elevated from(4.2±0.5) ml/s to(22.6±2.5) ml/s(P<0.01) and the postvoid residual volume reduced from(104.2±21.5) ml to(29.3±6.2) ml(P<0.01). The score of international prostate syndrome score and quality of life reduced from 26.4±3.6 and 5.1±0.3 to 8.7±2.4 and 2.5±0.4, respectively(P<0.01). Conclusions:transurethral plasma kinetic resection is safe and effective for the treatment of large prostate.
Objective:To investigate the safety and efficacy of the transurethral plasma kinetic resection of the patients with prostatic hyperplasia size. Methods:Forty-one patients with benign prostate hyperplasia were treated by transurethral bipolar plasmakinetic prostatectomy and their clinical data were retrospectively summarized. Results:The mean operation time was(82.5±9.2) minutes,and the mean blood loss was(195.5±65.8) ml. 3 cases were complicated with urethrostenosis,but no patient exhibited clinical sign of (transurethral resection syndrome. All cases were folowed up for 24 months,The Qmax elevated from(4.2±0.5) ml/s to(22.6±2.5) ml/s(P<0.01) and the postvoid residual volume reduced from(104.2±21.5) ml to(29.3±6.2) ml(P<0.01). The score of international prostate syndrome score and quality of life reduced from 26.4±3.6 and 5.1±0.3 to 8.7±2.4 and 2.5±0.4, respectively(P<0.01). Conclusions:transurethral plasma kinetic resection is safe and effective for the treatment of large prostate.
2011, 36(11): 1217-1219.
Abstract:
Objective:To explore the curative efficacy of sphincter-preserving surgery in the treatment of patients with super low rectal carcinoma. Methods:Fifty-four patients with super low rectal cancer received anal preservative operation were analyzed,inspecting anal function assessed after operation,and follow-up for 1,3,12 months. Results:All the cases were followed up for at least 16 months to 48 months. All patients were operated with no death and no anastomotic infection. Only one case suffered remained cancer cells in cutting margin,three cases anastomotic leakage and three cases anastomotic narrow. Two received Mile operation after 6 months because of local recurrence. Two patients died of other disease. Conclusions:By strict selection of cases, improving anastomosis and improving perioperative management, anal sphincter preserving operation is an ideal surgery choose for the patients with super low rectal cancer. The operation used in patients gave better functional results of treatment and better quality of their life.
Objective:To explore the curative efficacy of sphincter-preserving surgery in the treatment of patients with super low rectal carcinoma. Methods:Fifty-four patients with super low rectal cancer received anal preservative operation were analyzed,inspecting anal function assessed after operation,and follow-up for 1,3,12 months. Results:All the cases were followed up for at least 16 months to 48 months. All patients were operated with no death and no anastomotic infection. Only one case suffered remained cancer cells in cutting margin,three cases anastomotic leakage and three cases anastomotic narrow. Two received Mile operation after 6 months because of local recurrence. Two patients died of other disease. Conclusions:By strict selection of cases, improving anastomosis and improving perioperative management, anal sphincter preserving operation is an ideal surgery choose for the patients with super low rectal cancer. The operation used in patients gave better functional results of treatment and better quality of their life.
2011, 36(11): 1220-1222.
Abstract:
Objective:To investigate the influence of serum from patients with dermatomyositis/polymyositis(DM/PM) on the activity of human umbilical vein endothelial cells(HUVEC). Methods:The serum taken from 16 untreated DM/PM patients were enrolled in the DM/PM group who were evenly divided into pre-treatment group(8 cases) and post-treatment group(8 cases),and the serum from 13 healthy people acted as control. The HUVEC was cultured in vitro,and the influence of serum from patients with DM/PM on HUVEC was examined by MTT assay. Results:There was no significant difference in the activity of HUVEC between the DM/PM group and the control group(P>0.05). Compared with the control,the serum from the post-treatment group suppressed the proliferation of HUVEC at 24 h after treatment(P<0.01),but accelerated the proliferation of HUVEC at 72 h(P<0.05). Compared with the pre-treatment group,the serum from the post-treatment group suppressed the proliferation of HUVEC at 24 h after treatment (P<0.05),but no significant difference was observed between the two groups at 48 h and 72 h(P>0.05). Conclusions:The serum from patients with DM/PM may not affect or impair the activity of HUVEC in vitro; the serum from the post-treatment DM/PM patients may inhibit the activity of HUVEC after the first promotion in vitro.
Objective:To investigate the influence of serum from patients with dermatomyositis/polymyositis(DM/PM) on the activity of human umbilical vein endothelial cells(HUVEC). Methods:The serum taken from 16 untreated DM/PM patients were enrolled in the DM/PM group who were evenly divided into pre-treatment group(8 cases) and post-treatment group(8 cases),and the serum from 13 healthy people acted as control. The HUVEC was cultured in vitro,and the influence of serum from patients with DM/PM on HUVEC was examined by MTT assay. Results:There was no significant difference in the activity of HUVEC between the DM/PM group and the control group(P>0.05). Compared with the control,the serum from the post-treatment group suppressed the proliferation of HUVEC at 24 h after treatment(P<0.01),but accelerated the proliferation of HUVEC at 72 h(P<0.05). Compared with the pre-treatment group,the serum from the post-treatment group suppressed the proliferation of HUVEC at 24 h after treatment (P<0.05),but no significant difference was observed between the two groups at 48 h and 72 h(P>0.05). Conclusions:The serum from patients with DM/PM may not affect or impair the activity of HUVEC in vitro; the serum from the post-treatment DM/PM patients may inhibit the activity of HUVEC after the first promotion in vitro.
2011, 36(11): 1223-1224.
Abstract:
Objective:To acquire better diagnosis and treatment by analyzing clinicopathologic features of non-menopausal and menopausal patients with cervical cancer. Methods:The clinical data of 100 cases with cervical cancer were analyzed retrospectively, and divided into non-menopausal group (32 cases) and menopausal group (68 cases) according to menopausal or not. Clinical presentation,tumor size,histological type,tumor stage and tumor metastasis of the two groups were studied and processed statistical analysis. Results:The contact bleeding symptoms in the non-menopausal group were more than that of the menopause group (P<0.01),2 groups of irregular vaginal bleeding symptoms was significantly(P<0.05). The size of tumor in the non-menopausal group was bigger than that of the menopausal group(P<0.05); and the proportion of non-squamous cell carcinoma was also more than the menopausal group(P<0.05). The cases of the non-menopausal group had early tumor stage,more ⅠandⅡperiod and less Ⅳ period amount compared with menopause group. However,the tumor metastasis cases in the non-menopausal group were more than menopause group(P<0.05). Conclusions:The non-menopausal patients with cervical cancer can lead easeily to contact bleeding,and accompany with large tumor volume and high proportion non-squamous cell carcinoma. The tumor is easy to transfer and has poor prognosis although its tumor stage is early in the non-menopausal patient.
Objective:To acquire better diagnosis and treatment by analyzing clinicopathologic features of non-menopausal and menopausal patients with cervical cancer. Methods:The clinical data of 100 cases with cervical cancer were analyzed retrospectively, and divided into non-menopausal group (32 cases) and menopausal group (68 cases) according to menopausal or not. Clinical presentation,tumor size,histological type,tumor stage and tumor metastasis of the two groups were studied and processed statistical analysis. Results:The contact bleeding symptoms in the non-menopausal group were more than that of the menopause group (P<0.01),2 groups of irregular vaginal bleeding symptoms was significantly(P<0.05). The size of tumor in the non-menopausal group was bigger than that of the menopausal group(P<0.05); and the proportion of non-squamous cell carcinoma was also more than the menopausal group(P<0.05). The cases of the non-menopausal group had early tumor stage,more ⅠandⅡperiod and less Ⅳ period amount compared with menopause group. However,the tumor metastasis cases in the non-menopausal group were more than menopause group(P<0.05). Conclusions:The non-menopausal patients with cervical cancer can lead easeily to contact bleeding,and accompany with large tumor volume and high proportion non-squamous cell carcinoma. The tumor is easy to transfer and has poor prognosis although its tumor stage is early in the non-menopausal patient.
2011, 36(11): 1225-1227.
Abstract:
Objective:To expore the reasonable treatment program for axillary accessory breast by comparing three different surgery. Methods:Sixty-eight(glandular type) cases were treated with resection in axil wrinkle,34(fat type) cases with simply liposuction and 36(glandularand fat type) cases with resection combinated with liposuction. Results:All cases were primary healing and no case occured with infection,bleeding,lymph fistula,subcutaneous fluid and other complications. Outside of the breast top restore the contour line of the pectoralis major and good cosmetic result after surgery. Conclusions:Various procedures should be selected according to the different types of axillary accessory breast.
Objective:To expore the reasonable treatment program for axillary accessory breast by comparing three different surgery. Methods:Sixty-eight(glandular type) cases were treated with resection in axil wrinkle,34(fat type) cases with simply liposuction and 36(glandularand fat type) cases with resection combinated with liposuction. Results:All cases were primary healing and no case occured with infection,bleeding,lymph fistula,subcutaneous fluid and other complications. Outside of the breast top restore the contour line of the pectoralis major and good cosmetic result after surgery. Conclusions:Various procedures should be selected according to the different types of axillary accessory breast.
2011, 36(11): 1240-1241,1244.
Abstract:
Objective:To improve the CT images re-recognition on subdural hematoma at cerebral flax and tentorium of cerebellum in order to provide the reliable basis for correct clinical therapy. Methods:CT findings of 31 patients with traumatic subdural hematoma of cerebral flax and tentorium of cerebellum were analyzed retrospectively. Results:All of 31 cases were hyperdence,17 cases were cerebral flax subdural hematomas. They presented shape similitude as cerebral flax, but it was wider than normal, as the lesions presented as high density shadow with slender and sword,duramater presented straight,its external margain presented as wave or arc. Nine cases of cerebellum tentorium hematomas presented as flakes,crescent-shaped or sectors. Five cases of subdural hematomas of cerebral flax with cerebellum tentorium presented as falciform or "Y" shape. Conclusions:Subdural hematomas of cerebral flax and tentorium of cerebellum are typical subdural hematoma and characteristic features of CT,thin slice and coronal scan,MPR rebuilding, CT re-examination,can make accurate diagnosis.
Objective:To improve the CT images re-recognition on subdural hematoma at cerebral flax and tentorium of cerebellum in order to provide the reliable basis for correct clinical therapy. Methods:CT findings of 31 patients with traumatic subdural hematoma of cerebral flax and tentorium of cerebellum were analyzed retrospectively. Results:All of 31 cases were hyperdence,17 cases were cerebral flax subdural hematomas. They presented shape similitude as cerebral flax, but it was wider than normal, as the lesions presented as high density shadow with slender and sword,duramater presented straight,its external margain presented as wave or arc. Nine cases of cerebellum tentorium hematomas presented as flakes,crescent-shaped or sectors. Five cases of subdural hematomas of cerebral flax with cerebellum tentorium presented as falciform or "Y" shape. Conclusions:Subdural hematomas of cerebral flax and tentorium of cerebellum are typical subdural hematoma and characteristic features of CT,thin slice and coronal scan,MPR rebuilding, CT re-examination,can make accurate diagnosis.
2011, 36(11): 1242-1244.
Abstract:
Objective:To investigate the clinical value of CT and digital mammography for diagnosis of breast neoplasm. Methods:Forty-five patients suspected as breast cancer underwent CT imaging and mammography,and compared to the results of histopathological examination. The differences in diagnosis were compared with these examinations. Results:The positive detection rates of CT and mammography were 84.4% (38/45) and 93.3% (42/45) respectively. The combination positive detection rate was 97.8% (44/45). In detecting breast cluster of calcification,the sensitivity of mammography was 73.3% (33/45),which was better than CT scan(46.7%, 21/45). The axillary lymph metastases were found in 34 patients. In detecting the axillary lymph metastases of the breast carcinoma,the sensitivity of CT scan was 88.2% (30/34),which was better than mammography(67.6%,23/34). Conclusions:The mammography and CT play the important role in diagnosis of breast neoplasm and showed the different character. The mammography combined with CT can improve the accurate rate of diagnosis.
Objective:To investigate the clinical value of CT and digital mammography for diagnosis of breast neoplasm. Methods:Forty-five patients suspected as breast cancer underwent CT imaging and mammography,and compared to the results of histopathological examination. The differences in diagnosis were compared with these examinations. Results:The positive detection rates of CT and mammography were 84.4% (38/45) and 93.3% (42/45) respectively. The combination positive detection rate was 97.8% (44/45). In detecting breast cluster of calcification,the sensitivity of mammography was 73.3% (33/45),which was better than CT scan(46.7%, 21/45). The axillary lymph metastases were found in 34 patients. In detecting the axillary lymph metastases of the breast carcinoma,the sensitivity of CT scan was 88.2% (30/34),which was better than mammography(67.6%,23/34). Conclusions:The mammography and CT play the important role in diagnosis of breast neoplasm and showed the different character. The mammography combined with CT can improve the accurate rate of diagnosis.
2011, 36(11): 1245-1246.
Abstract:
Objective:To investigate the application of CT technology in diagnosis of leukoaraiosis (LA) and Binswanger disease (BD). Methods:The CT examination and clinical data of 96 patients with leukoaraiosis and 56 patients with Binswanger disease were collected and analyzed. Results:CT types and clinical features were different in 2 groups. Ventriculomegaly,multipled lacunar infarct and single lacunar infarct in BD group were more common than that of LA group. Compared with LA group,symptoms in BD group was more seriously. Conclusions:The CT features of LA is effective for diagnosis of disease.
Objective:To investigate the application of CT technology in diagnosis of leukoaraiosis (LA) and Binswanger disease (BD). Methods:The CT examination and clinical data of 96 patients with leukoaraiosis and 56 patients with Binswanger disease were collected and analyzed. Results:CT types and clinical features were different in 2 groups. Ventriculomegaly,multipled lacunar infarct and single lacunar infarct in BD group were more common than that of LA group. Compared with LA group,symptoms in BD group was more seriously. Conclusions:The CT features of LA is effective for diagnosis of disease.
2011, 36(11): 1247-1248.
Abstract:
Objective:To investigate the clinical significance and the image types of ultrasound of hepatocellular carcinoma(HCC) with portal vein tumor thrombus(PVTT) and portal vein blood thrombus(PVBT). Methods:HCC with PVTT of 32 cases(PVTT group) and HCC with PVBT of 18 cases(PVBT group) by transcantheter hepatic arterial chemo-embolization(THAE) were reported. Thirtytwo cases in PVTT group and 4 cases in PVBT group were treated with ultrasound-guided percutaneous portal pathway. The hepatic arteio-venous fistula in the two groups was excluded. Results:According to the image classification of ultrasound,in PVTT group,there were including the type of complete obstruction of the portal vein lumen(n=17),the type of incomplete obstruction(n=6) and the type of invasion the portal wall(n=9). In PVBT group,there were including the type of complete obstruction of the portal vein lumen (10 cases) and the type of incomplete obstruction (8 cases). In PVTT group, the blood supply was revealed in 29 cases by the ultrasound examination while in PVBT group,only one case was with uncertainly blood supply,there was a highly significant difference about the blood supply between PVTT and PVBT group(χ2=38.11,P<0.01). Conclusions:It has a great value in clinical application of the image classification of ultrasonic findings about portal vein thrombus and PVTT.
Objective:To investigate the clinical significance and the image types of ultrasound of hepatocellular carcinoma(HCC) with portal vein tumor thrombus(PVTT) and portal vein blood thrombus(PVBT). Methods:HCC with PVTT of 32 cases(PVTT group) and HCC with PVBT of 18 cases(PVBT group) by transcantheter hepatic arterial chemo-embolization(THAE) were reported. Thirtytwo cases in PVTT group and 4 cases in PVBT group were treated with ultrasound-guided percutaneous portal pathway. The hepatic arteio-venous fistula in the two groups was excluded. Results:According to the image classification of ultrasound,in PVTT group,there were including the type of complete obstruction of the portal vein lumen(n=17),the type of incomplete obstruction(n=6) and the type of invasion the portal wall(n=9). In PVBT group,there were including the type of complete obstruction of the portal vein lumen (10 cases) and the type of incomplete obstruction (8 cases). In PVTT group, the blood supply was revealed in 29 cases by the ultrasound examination while in PVBT group,only one case was with uncertainly blood supply,there was a highly significant difference about the blood supply between PVTT and PVBT group(χ2=38.11,P<0.01). Conclusions:It has a great value in clinical application of the image classification of ultrasonic findings about portal vein thrombus and PVTT.
2011, 36(11): 1251-1252.
Abstract:
Objective:To explore the value of human epididymis protein 4(HE4) in diagnosis of ovarian cancer in different clinical stages,and determine whether HE4 is better than cancer antigen 125(CA125),another tumor marker of ovarian cancer. Methods:The serum HE4 levels in 46 patients with ovarian cancer(among them,the numbers of early,intermediate and terminal cancer were 9,31 and 6,respectively), 50 patients with benign ovarian tumour and 50 healthy women were measured by automatic chemiluminescence method. Results:The level of serum HE4 was significantly higher in ovarian cancer patients than those in other two groups(P<0.01). In 9 early ovarian cancer patients,the positive rate of HE4 was 78%,which was significantly higher than CA125,the positive rate was 55%. Conclusions:HE4 is a specific marker and it is better than CA125 in diagnosis of ovarian cancer,especially it is important for diagnosis of early ovarian cancer.
Objective:To explore the value of human epididymis protein 4(HE4) in diagnosis of ovarian cancer in different clinical stages,and determine whether HE4 is better than cancer antigen 125(CA125),another tumor marker of ovarian cancer. Methods:The serum HE4 levels in 46 patients with ovarian cancer(among them,the numbers of early,intermediate and terminal cancer were 9,31 and 6,respectively), 50 patients with benign ovarian tumour and 50 healthy women were measured by automatic chemiluminescence method. Results:The level of serum HE4 was significantly higher in ovarian cancer patients than those in other two groups(P<0.01). In 9 early ovarian cancer patients,the positive rate of HE4 was 78%,which was significantly higher than CA125,the positive rate was 55%. Conclusions:HE4 is a specific marker and it is better than CA125 in diagnosis of ovarian cancer,especially it is important for diagnosis of early ovarian cancer.
2011, 36(11): 1253-1255.
Abstract:
Objective:To evaluate the relationship between the levels of lipoprotein,apoprotein(Apo),ApoB/ApoA-Ⅰ ratio,and LP (a) and coronary heartdisease(CHD). Methods:Sixty-one patients diagnosed as CHD were as the CHD group,20 healthy people were selected as control. The levels of TG,TC,HDL-C,LDL-C,ApoB,ApoA-Ⅰ,and LP(a) were detected. Results:There were significantly differences between the group CHD and control in the levels of HDL-C,ApoB,LP(a),and ApoB/ApoA-Ⅰratio(P<0.05). Among lipid index,HDL-C,ApoB and LP(a) were the independent risk factors for CHD by using of Logistics stepwise regression analysis. Correlation analysis found that ApoB,Lp(a) and ApoB/ApoA-Ⅰ ratio were positive correlation with CHD. There were no significant correlations for other results. Conclusions:There are more valuable to predict the risk factor when associated with ApoB,ApoB/ApoA-Ⅰ ratio and Lp(a).
Objective:To evaluate the relationship between the levels of lipoprotein,apoprotein(Apo),ApoB/ApoA-Ⅰ ratio,and LP (a) and coronary heartdisease(CHD). Methods:Sixty-one patients diagnosed as CHD were as the CHD group,20 healthy people were selected as control. The levels of TG,TC,HDL-C,LDL-C,ApoB,ApoA-Ⅰ,and LP(a) were detected. Results:There were significantly differences between the group CHD and control in the levels of HDL-C,ApoB,LP(a),and ApoB/ApoA-Ⅰratio(P<0.05). Among lipid index,HDL-C,ApoB and LP(a) were the independent risk factors for CHD by using of Logistics stepwise regression analysis. Correlation analysis found that ApoB,Lp(a) and ApoB/ApoA-Ⅰ ratio were positive correlation with CHD. There were no significant correlations for other results. Conclusions:There are more valuable to predict the risk factor when associated with ApoB,ApoB/ApoA-Ⅰ ratio and Lp(a).
2011, 36(11): 1261-1263.
Abstract:
Objective:Developing a computer software for analysis of arterial blood gases for clinical and teaching use,which can analog display the process of diagnosis and analysis. Methods:The software was edited by means of elanguage and combined with Windows operating system. Results:The software accurately determined different acid-base imbalances and respiratory dysfunction. The software analog displayed that the process of diagnosis and analysis of blood gas analysis by the six-step. After determining the type of acid-base imbalance,the software provided the incidence of the causes,clinical manifestations and treatment recommendations of it for clinicians reference. Conclusions:The software can be used as a reference by clinical doctors in diagnosis and analysis of blood gas analysis,it could also be used for teaching and training. It is scientific,advanced and valuable in clinical practice.
Objective:Developing a computer software for analysis of arterial blood gases for clinical and teaching use,which can analog display the process of diagnosis and analysis. Methods:The software was edited by means of elanguage and combined with Windows operating system. Results:The software accurately determined different acid-base imbalances and respiratory dysfunction. The software analog displayed that the process of diagnosis and analysis of blood gas analysis by the six-step. After determining the type of acid-base imbalance,the software provided the incidence of the causes,clinical manifestations and treatment recommendations of it for clinicians reference. Conclusions:The software can be used as a reference by clinical doctors in diagnosis and analysis of blood gas analysis,it could also be used for teaching and training. It is scientific,advanced and valuable in clinical practice.
2011, 36(11): 1263-1264.
Abstract:
Objective:To investigate the method applied in the extraction of polysaccharides in Cordyceps militaris mycelia. Methods:Water-extraction method and microwave-assisted extraction method were applied in the extraction of polysaccharides. The content of polysaccharides in mycelia was determined by phenol-vitriol method. Results:The coarse polysaccharides extractive rate of waterextraction method was 22.26% in Cordyceps militaris mycelia,and the rate of water-extraction method was 15.16%. Conclusions:The extractive rate of water-extraction method is higher than the rate of microwave-assisted extraction method. But the technology of waterextraction method was complex and time consuming. The technology of microwave-assisted extraction method was simple and speedy.
Objective:To investigate the method applied in the extraction of polysaccharides in Cordyceps militaris mycelia. Methods:Water-extraction method and microwave-assisted extraction method were applied in the extraction of polysaccharides. The content of polysaccharides in mycelia was determined by phenol-vitriol method. Results:The coarse polysaccharides extractive rate of waterextraction method was 22.26% in Cordyceps militaris mycelia,and the rate of water-extraction method was 15.16%. Conclusions:The extractive rate of water-extraction method is higher than the rate of microwave-assisted extraction method. But the technology of waterextraction method was complex and time consuming. The technology of microwave-assisted extraction method was simple and speedy.
2011, 36(11): 1265-1268.
Abstract:
Objective:To investigate the relationship between the status of coping style of nurses and demographic characteristics and provide reference for nursing managers to make training plan. Methods:Simple coping style questionnaire was used to survey 543 nurses in 5 general hospital of Bengbu in Anhui province. Results:There were statistical significances of the positive coping style scores of nurses in different age,position and educational background(P<0.05-P<0.01). There were statistical significances of the negative coping style scores of nurses in different age and position(P<0.05-P<0.01). The negative coping style scores of nurses had no statistical significance in different educational background(P>0.05). The positive coping style scores of nurses aged 21-50 were increased with age. The negative coping style scores of nurses had statistical significance in different department (P<0.01). Conclusions:The more positive coping style and less negative coping style are adopted by nurses. The coping style of nurses is affected by age,position and educational background. The effective coping style is adopted to relieve pressure of nurses and improve nurses' mental health level according to the demography characteristics of nurses.
Objective:To investigate the relationship between the status of coping style of nurses and demographic characteristics and provide reference for nursing managers to make training plan. Methods:Simple coping style questionnaire was used to survey 543 nurses in 5 general hospital of Bengbu in Anhui province. Results:There were statistical significances of the positive coping style scores of nurses in different age,position and educational background(P<0.05-P<0.01). There were statistical significances of the negative coping style scores of nurses in different age and position(P<0.05-P<0.01). The negative coping style scores of nurses had no statistical significance in different educational background(P>0.05). The positive coping style scores of nurses aged 21-50 were increased with age. The negative coping style scores of nurses had statistical significance in different department (P<0.01). Conclusions:The more positive coping style and less negative coping style are adopted by nurses. The coping style of nurses is affected by age,position and educational background. The effective coping style is adopted to relieve pressure of nurses and improve nurses' mental health level according to the demography characteristics of nurses.
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