• 中国科技论文统计源期刊
  • 中国科技核心期刊
  • 中国高校优秀期刊
  • 安徽省优秀科技期刊

2012 Vol. 37, No. 8

Display Method:
Effects of cisplatin on the proliferation and SATB1 expression of HepG2 cells
YU Li, LING Yun-zhi
2012, 36(8): 877-880.
Abstract:
Objective:To observe the expressions of the special AT-rich sequence-binding protein 1(SATB1) in different hepatoma cell lines and the effects of Cisplatin on the morphology and SATB1 expression of HepG2 cells.Methods:The mRNA expressions of SATB1 of three hepatoma cell lines,HepG2,BEL-7402 and SMMC-7721 were detected using reverse transcription polymerase chain reaction.After HepG2 cells were treated with different concentrations(2.5,5.0 and 10.0 g/ml) of Cisplatin for 24 hours,the cell morphology were observed with inverted microscope and the mRNA expressions of SATB1 were examined using RT-PCR.Results:The expressions of SATB1 in BEL-7402,SMMC-7721 and HepG2 had no statistically significant difference(P0.05).The changes of cell morphology,the decreasing in cell number and increasing in cell damage and death were observed under inverted microscope after HepG2 cells were treated with Cisplatin for 24 hours.The mRNA expressions of SATB1 decreased gradually with the increasing concentrations of Cisplatin,and the mRNA expressions of SATB1 treated with 5.0 and 10.0 g/ml of Cisplatin had statistical significance compared with that of control group(P0.05).Conclusions:All three hepatoma cell lines can express SATB1.Cisplatin can inhibit the proliferation of HepG2 cells and the expression of SATB1,so as to inhibit the growth of hepatoma cells.
Protective effects of ischemic/reperfusion postconditioning on rat acute myocardial ischemia
ZHOU Ru-juan, WANG Xiu-zhen
2012, 36(8): 880-883.
Abstract:
Objective:To establish the rat acute myocardial ischemia/reperfusion model using capsule and observe the protective effects of ischemic postconditioning(IPost) on rats.Methods:Thirty-six rats were randomly divided into sham operation group,ischemia/reperfusion group(I/R group) and Ipost group(12 rats in each group),and all animals were sacrificed at the end of reperfusion.The cardiac functional parameters,plasma myocardial enzymes,apoptosis index and the scope of myocardial infarct were determined,and the levels of Bcl-2,Bax,Caspase-3 of cardiac muscular tissue were detected by Western blot.Results:Compared with I/R group,the cardiac functional parameters of Ipost group were obviously improved(P0.01),while their plasma myocardial enzymes,apoptosis index were significantly lower and scopes of myocardial infarct were significantly less(P0.05).The level of Bcl-2 of Ipost group was significantly higher than that of the I/R group,and the levels of Bax and Caspase-3 of Ipost group were significantly lower than those of the I/R group(P0.01).Conclusions:The method of ligating coronary artery with capsule is fast and convenient for Ipost,which can alleviate myocardial ischemia/reperfusion injury,reduce myocardial cells apoptosis and downsize the scope of myocardial infarct.The protective mechanism is possible associated with the activation of RISK signaling pathway.
Protective effects of sevoflurane on liver ischemia reperfusion injury in rabbits
LING Yun-zhi, YU Li, LIANG Qi-sheng, LI Xiao-hong, WANG Nan-hai
2012, 36(8): 884-887.
Abstract:
Objective:To investigate the effects of sevoflurane on liver ischemia reperfusion injury in rabbits.Methods:Twenty-0ne rabbits were randomly divided into sham operation group(S),ischemia reperfusion group(IR) and sevoflurane ischemia reperfusion group(Sev-IR).Rabbits in IR group and Sev-IR group suffered from ischemia for 45 minutes and were followed by reperfusion for 60 minutes.Sev-IR group was anesthetized with sevoflurane.The concentrations of MDA and XOD of liver tissue were determined.The histopathologic changes in the liver were also observed.The expressions of c-fos protein were observed through immunohistochemisty.Results:The concentrations of MDA and XOD increased significantly after liver ischemia-reperfusion.The sinusoid was expanded and congestion obviously.The hepatic cells were hydropic degeneration and vacuole degenerated.Some of them were spotty necrosis.The protein of c-fos was positive expression.When using sevoflurane,the concentrations of MDA and XOD were statistical significantly decreased compared with IR group(P0.05).The hepatic histopathological changes were improved.The degree of degeneration and necrosis of hepatic cells and the congestion of hepatic sinusoid lessened.The expression of c-fos was down regulated significantly(P0.05).Conclusions:The injury of liver ischemia reperfusion can release mass oxygen radicals and increase the expression of c-fos.This can induce hepatic tissue injury.Sevoflurane can protect liver from ischemia reperfusion injury.Its possible mechanisms are restraining excess oxidizing reaction and decreasing the expression of c-fos protein.
Perioperative management of 233 cases of congenital heart diseases with diminutive pulmonary blood
SHI Chao, WANG Zu-yi, LIU Xue-gang, TANG Zhen, ZHOU Xiao, LIU Ge, ZHANG Lei
2012, 36(8): 887-889.
Abstract:
Objective:To sum perioperative management experiences of congenital heart diseases with diminutive pulmonary blood.Methods:The data of 233 cases with congenital heart diseases with diminutive pulmonary blood were analyzed retrospectively.The appropriate surgical programme was formulated after the diagnosis was confirmed by cardiac echocardiography,magnetic resonance imaging or spiral CT and pulmonary vessels were evaluated.Two hundred and one cases were treated with anatomical correction surgery and 34 cases were treated with physical or palliative surgery.All monitoring index of all cases were observed,and which were given full sedation,proper posture,circulation and respiratory support after opertaion.Results:The cardiopulmonary bypass time was(118.2327.25) minutes,aortic cross-clamping time 73.26 minutes,postoperative ventilation time(17.6412.23) minutes,average application amount of dopamine(7.522.12) mgkg-1min-1,intensive care time for(73.224.5) hours and postoperative hospital stay time(9.55.6) days.Eleven patients died(mortality as 73.3%) during intraoperative.Fifty-two patients had complications(incidence rate as 23.4%) and no one died.Conclusions:The objective and comprehensive assessment of preoperative imaging,the correct choice of operation and postoperative care and treatment can greatly improve the surgical effects,reduce the incidence of surgical complications and mortality.
The clinical application of the modified sagittal split ramas osteotomy in rectifying mandibular deviation
WU Zhi-gang, ZHANG Kai, LIAO Sheng-kai, XU Tao, WANG De-shun, GAO Yi-lin
2012, 36(8): 890-892.
Abstract:
Objective:To investigate the effects of the modified sagittal split ramas osteotomy in treatment of mandibular deviation.Methods:Six mandibular deviation cases were included in this study,there were 3 cases with simply deformity,2 cases with protrusion and partial jaw deformity and 1 case with partial secondary jaw malformation.SNA,SNB and ANB by X-ray cephalometric measurement were 79-83,80-88 and-52 ,respectively.All patients were operated with the modified sagittal split ramas osteotomy combined with preoperative and postoperative orthodontic treatment.Results:Wound healing had no serious complications and the relations of the upper and lower tooth jaw and facial morphology were good.Conclusions:Treatment of mandibular deviation with the modified sagittal split ramas osteotomy combined with orthodontic treatment is a effective way,which is worthy of being widely applied in clinic.
Clinical effect analysis of laparoscopic splenectomy and traditional open splenectomy
ZHOU Shao-bo, CHU Liang, JIANG Lei
2012, 36(8): 893-895.
Abstract:
Objective:To investigate the the clinic application value of laparoscopic splenectomy(LS).Methods:Thirty-one cases with splenectomy were treated with LS(15 cases) and open splenectomy(OS)(16 cases).The operation time,intraoperative bleeding,postoperative recovery and complications and hospitalization expense of all cases were evaluated.Results:All cases were successfully operated.The length of incision,the time of anal exhaust and out of bed and the hospital stay of LS group were shorter than that of OS group(P0.05 to P0.01),while its hospitalization expense was high(P0.01).The operative time,bleeding loss and complications of two groups were not statistically significant(P0.05).Conclusions:Laparoscopic splenectomy is a safe,feasible,good effects and minimally invasive surgery for most spleen diseases.
The causes and prevention of bile leakage caused by laparoscopic cholecystectomy
LI Pei-sheng, ZHOU Shao-bo, BEN Da-gang, CHENG Kai
2012, 36(8): 896-897.
Abstract:
Objective:To investigate the causes and treatment of bile leakage caused by laparoscopic cholecystectomy(LC).Methods:The clinical data of 8 cases with bile leakage caused by LC were retrospectively analyzed.Results:Six cases with bile leakage caused by aberrant bile duct or cholangiole injuries were cured with abdominal cavity drainage and drugs.Two cases with late-occurred bile leakage including 1 case opening in common hepatic duct and 1 case opening in right hepatic duct were cured by opening repair and T-tube drainage.No cholangitis and bile duct stenosis were found during following-up for 6 months to 2 years.Conclusions:Extrahepatic bile duct and aberrant bile duct injuries were the most common reasons of bile leakage after LC.Abdominal cavity drainage,bile duct repair and T-tube drainage are the main methods to treat bile leakage after LC and prevent complications.
A comparative study of treatment inguinal hernia with laparoscopic hernia repair and open hernia repair
ZHANG Jie, ZHOU Shao-bo, CHU Liang, ZHANG Xin
2012, 36(8): 898-900.
Abstract:
Objective:To compare the effects of four different repairs on inguinal hernia.Methods:One hundred cases with primary inguinal hernia of NyhusⅠⅢ were randomly divided into four groups.Group Ⅰwere treated with open properitoneal repair,group Ⅱ were treated with Lichtenstein tension-free repair,group Ⅲ were treated with transabdominal properitoneal(TAPP) repair and group Ⅳ were treated with laparoscopic totally extraperitoneal(TEP) repair.Results:The operative time of group Ⅲ and Ⅳ were longer than that of group Ⅰ and Ⅱ(P0.01).Compared with group Ⅱ,the operative time of groupⅠwas long(P0.05).Postoperative pain of group Ⅰ and Ⅱwere stronger than that of group Ⅳ within 24 hours after operation(P0.01 and P0.05).One case in group Ⅲ and one in group Ⅳ conversed to open procedure.The activity time of cases treated with laparoscopic operation were significantly shorter than that of group Ⅰ and Ⅱ(P0.01).Conclusions:The effects of TEP and TAPP are similar.Laparoscopic hernia repair is less postoperative pain and fast recovery.
The etiological diagnosis of subarachnoid hemorrhage caused by aneurysm
QIAN Wei-dong, QU Hong-dang, CHEN Yu-hua, ZHANG Yang
2012, 36(8): 901-903.
Abstract:
Objective:To explore the value of CT angiography(CTA) in the etiological diagnosis of subarachnoid hemorrhage(SAH) caused by aneurysm.Methods:Twenty-four spontaneous SAH patients diagnosed by CT plain scan were detected for comparative analysis using CTA and digital subtraction angiography(DSA).Results:Twenty-two cases with 26 aneurysms in 24 cases were found by CTA.CTA displayed the location,size,shape,neck and surrounding tissue of aneurysm.Using DSA as the gold standard,the sensitivity and specificity of CTA were 92.86% and 100.00% respectively.Conclusions:CTA can be a preferred method for the early etiological diagnosis of SAH patients,especially for critical patients.
Correlation of the levels of preoperative serum squamous cell carcinoma antigen with early-stage lymphatic metastasis of squamous cell cervical cancer
YANG Bo, GUO Su-yang, LI Sheng-ze
2012, 36(8): 904-907.
Abstract:
Objective:To investigate the correlation of preoperative serum squamous cell carcinoma antigen(SCCAg) with early-stage lymphatic metastasis of squamous cell cervical cancer.Methods:The clinically pathologic data of 391 cases with early-stage squamous cell cervical cancer undergoing radical hysterectomy were analyzed preoperatively.The serum levels of SCC-Ag preoperation were detected,and its correlation with the clinically pathologic data were statistically analyzed.Results:The levels of SCCAg preoperative and the FIGO staging,tumor size,depth of muscular infiltration,parametrial involvement and lymphatic metastasis had significantly association(P0.01),but the degree of differentiation and tumor vascular invasion was not statistically significant(P0.05).The lymph node metastasis and tumor diameter were the independent risk factors of affecting serum marker levels and lymphatic metastasis had more effects on the levels of SCC-Ag than tumor diameter.The better sensitivity(0.54) and specificity(0.83),highest Yonden index(0.37) and best predictive results could be achieved when the cut-off value was 2.5 ng/ml during the Ⅰb1 stage period.But forⅠb2 and Ⅱa stage,the cut-off value was 4.5 ng/ml.Conclusions:The serum levels of SCC-Ag preoperation have a certain value in evaluating the lymphatic metastasis.During Ⅰb1 and Ⅰb2 and Ⅱa.stage,the predictive results are the best when the cut-off values are 2.5 and 4.5 ng/ml respectively.
The analysis of clinical characteristics of acute promyelocytic leukemia with CD2 positive
GENG Ying-hua, ZHOU Li-li, LI Jun, HU Zhong-li, ZHU Jun-feng, YANG Yan-li
2012, 36(8): 908-910.
Abstract:
Objective:To explore the clinical characteristics of acute promyelocytic leukemia(APL) with CD2+.Methods:The immunophenotype of 19 cases with APL were detected by flow cytometry.All cases were divided into CD2+ and CD2-group according to the results of immunophenotype.The clinical performance,laboratory examination and therapeutic effects of two groups were analysed.Results:Compared with 15 cases with CD2-,the higher WBC counts and lower fibrinogen contents of 4 cases with CD2+ were observed(P0.05),and the differences of platelet counts and CR time of two groups had no statistical significance(P0.05).The CD34 expressions were detected in all 4 cases with CD2+,which could complete remission after treatment.The CD34 expression was detected in 1 of 15 cases with CD2-and other 14 cases could complete remission after treatment.Conclusions:APL with CD2+ are often accompanied by high WBC counts and risk of serious bleeding,which can be used as an indicator to monitor the minimal residual disease of APL.
Short-term curative effect of neoadjuvant chemotherapy on locally adanced cervical cancer:a report of 25 cases
JIN Li-jie, FANG Mei-li, YE Guo-liu
2012, 36(8): 910-912.
Abstract:
Objective:To investigate the effect of preoperative neoadjuvant chemotherapy with PT on locally advanced cervical cell cancer.Methods:Fifty cases of locally advanced cervical cell cancer in stageⅠB-ⅡA were retrospectively analyzed.Twenty-five cases were managed preoperatively by regiment of PT chemotherapy(paclitaxel+carboplatin) for 2 cycles and followed by the therapeutic value.The radical surgery was conducted after two weeks of the chemotherapy.The other 25 cases were only managed by radical surgery.Results:Preoperative neoadjuvent chemotherapy with PT significantly decreased the primary tumor sizes(P0.05).The total effective rate was 76.00%.Chemotherapy adverse reaction in NACT group was light.Operation time and perioperative bleeding in NACT group was lower than those in the control group(P0.05 to P0.01).No significant difference existed in postoperative recovery time of bladder function and gastrointestinal function between two groups(P0.05).High-risk pathological factor rate in NACT group and control group was not statistically significant(P0.05).Conclusions:Preoperative chemotherapy with PT in locally adanced cervical cancer can reduce primary tumor sizes,decrease postoperative infiltration around uterine,reduce lymph node metastasis,and reduce the postoperative complications and recurrence.It is worthy of clinical application.
Characteristics of dysglycemia in preterm infants and related risk factors
ZHAO Wu, XIA Qun, XU Jia-xin
2012, 36(8): 913-917.
Abstract:
Objective:To explore the characteristics and regulation of dysglycemia in preterm infants,and related risk factors.Methods:Eighty-four preterm infants within 3 days of life were divided into two groups:one group weighing less than 1 500 g(30 cases) and the other weighing more than or equal to 1 500 g(54 cases).After admission,the whole blood glucose levels of all preterm infants were immediately measured using glucometer.Intravenous glucose infusion was then given at a rate of 6 mgkg-1min-1,and the glucose infusion rate was subsequently adjusted on the basis of measured glucose levels to maintain euglycemia.Insulin therapy was administered when necessary.The characteristics of dysglycemia in preterm infants and related risk factors were analysed.Results:Hypoglycemia occurred in 11 infants(13.1%) after admission.The hypoglycemia incidence was significantly higher in 1 500 g group than in 1 500 g group(26.7% vs 5.6%,P0.05).Hyperglycemia occurred in 41 infants(48.8%) after infusion of glucose.The hyperglycemia incidence was considerably higher in 1 500 g group than in 1 500 g group(73.3% vs 35.2%,P0.01).The hyperglycemia in 39 of the 41 preterm infants was controlled by gradually decreasing the glucose infusion rate.Persistent hyperglycemia(14 mmol/L) in the remaining two preterm infants was controlled by insulin treatment.Multivariate logistic regression analysis showed that birth weight less than 1 500 g(P0.05),asphyxia(P0.01),hypoxic brain damage(P0.01),and intracranial hemorrhage(P0.05) were significantly associated with hyperglycemia in preterm infants.Conclusions:Preterm infants are at high risk of dysglycemia during the first week of life,especially for very low birth weight infants,and hyperglycemia is more common than hypoglycemia.For most preterm infants,hyperglycemia can be controlled by reducing the glucose infusion rate.Weight less than 1 500 g,asphyxia,hypoxic brain damage,and intracranial hemorrhage were independent risk factors for preterm infant hyperglycemia.
Clinical observation of trabeculectomy on 27 glaucoma patients with persistent intraocular hypertension
LI Yuan-long, YIN Cui-yun, GU Li-li, JIANG Jie
2012, 36(8): 917-919.
Abstract:
Objective:To explore the operation key points,safety and therapeutic effects of trabeculectomy on glaucoma with persistent intraocular hypertension.Methods:Twenty-seven patients with persistent intraocular hypertension were treated with trabeculectomy.The eyesight,intraocular pressure(IOP),the depth of anterior chamber and complications were detected after operation.Results:All operations were completed successfully.The suprachoroidal hemorrhage and malignant glaucoma were not found at the intraoperation and postoperation.Five eyes with hyphema and 10 eyes with shallow anterior chamber recovered after treatment.The eyesights of 18 eyes were improved and the IOP of 24 eyes(88.89%) were controlled less than 21 mmHg without drugs treatment.Conclusions:Surgical intervention should be performed when IOP can not be controlled by drugs,which can shorten the course of disease and obtain beneficial effects.
The effects of TME with preserving pelvic autonomic nerve on sexual and urinary function of male
WANG Ya-guo, QIAN Jun
2012, 36(8): 920-923.
Abstract:
Objective:To investigate the effects of total mesorectal excision(TME) with pelvic autonomic nerve preservation(PANP) on sexual and urinary function of male.Methods:One hundred and eight cases with radical resection for rectal carcinoma were divided into PANP and TME group(56 cases) plus TME group(52 cases) according to different operative techniques.Sexual dysfunction,urination disorder rates and local recurrence rates were compared.Results:Erectile dysfunction,ejaculation disorder and urination dysfunction rates of TME plus PANP group and TME group were 32.1% and 78.8%,35.7% and 78.8% and 26.8% and 82.7%,respectively,which differences had statistical significance(P0.01).The local recurrence rates of TME plus PANP group and TME were 12.5% and 11.5%,respectively,which differences had no statistical significance(P0.05).Conclusions:TME with PANP can effectively reduce the local recurrence and the sexual and urinary dysfunction rates.
The effects of tympanoplasty through mastoidectomy treatment of 30 cases with otitis media with cholesteatoma
ZHAO Cui-ying
2012, 36(8): 923-924.
Abstract:
Objective:To investigate the effects of tympanoplasty through mastoidectomy in treatment of otitis media with cholesteatoma.Methods:Thirty cases with otitis media with cholesteatoma were treated with tympanoplasty through mastoidectomy.Results:Survival of transplanted fascia and dry ears of 30 cases were observed during following up for 6 months to 2 years.Puretone audiometry and the gas Guide mean of language frequency were improved after sugery.Conclusions:Treatment of otitis media with cholesteatoma by tympanoplasty through mastoidectomy can completely remove lesion,improve hearing and decrease recurrence rates,which has certain clinical application value.
Clinical analysis of 15 patients with severe craniocerebral injury complicated with neurogenic pulmonary edema
SHI Shuang-yu, HUANG Jun, WANG Kang-sheng
2012, 36(8): 925-927.
Abstract:
Objective:To explore the key points of diagnosis and treatment of severe craniocerebral injury complicated with neurogenic pulmonary edema(NPE).Methods:Fifteen patients with severe craniocerebral injury complicated with NPE were treated with reducing intracranial pressure and keeping airway open.The vasodilator agents,relieving pulmonary circulating load and controlling pulmonary infection were applied when hypoxic condition was not corrected after inhaling oxygen.Results:Seven patients survived and 8 patients died.Conclusions:The severe craniocerebral injury complicated with NPE is serious complications of severe craniocerebral injury.Early diagnosis and treatment are the key of improving the success rate of treatment and lowering the death rate.
Efficacy of urapidil on acute left ventricular failure
YU Min, ZHENG Zhi-gang, TIAN Feng
2012, 36(8): 927-929.
Abstract:
Objective:To observe the effect of urapidil in treatment of acute left ventricular failure(ALVF).Methods:One hundred patients with ALVF were randomly divided into treatment group(57 cases) and control group(43 cases).The treatment group received intravenous drip of urapidil and the control group intravenous drip of nitroglycerin both in addition to the routine therapy.The cardiac function,heart rate,blood pressure,left ventricular ejection fraction(LVEF),left ventricular end-systolic dimension(LVESD) and plasma B-type natriuretic peptide(BNP) of both groups were observed 72 hours after treatment.Results:The treatment group displayed better therapeutic effects than the control group(P0.05).The treatment group were superior to the control group in the recovery of heart rate and blood pressure(P0.05-P0.01).The LVESD and BNP of both groups decreased obviously and the LVEF increased significantly(P0.05-P0.01) after the therapy,but the changes were more significant in the treatment group(P0.01).Conclusions:Urapidil is superior to nitroglycerin in treatment of ALVF with definite effect.
Expression and clinical significance of KAI1/CD82 in laryngeal squamous cell carcinoma
ZHANG Zhen-huan, WU Li-gao, WU Shi-wu
2012, 36(8): 930-932.
Abstract:
Objective:To investigate the expression of KAI1/CD82 in laryngeal squamous cell carcinoma(LSCC),and its correlation with clinic pathological parameters.Methods:The expression of KAI1/CD82 of 83 specimens of LSCC tissue and 20 specimens of normal laryngeal tissue were detected by immunohistochemistry.Results:The positive expression rates of KAI1/CD82 in LSCC tissue and normal laryngeal tissue were 41.0% and 90.0%,respectively,which had significant difference(P0.01).The high differentiation and no lymph node metastasis of LSCC tissues were observed.The positive expression rates of KAI1/CD82 of cases with grade Ⅰ-Ⅱ were significantly higher than that of cases with grade Ⅲ-Ⅳ and lymph node metastasis(P0.05 to P0.01),while its expression was not associated with age,gender,diameter and location of tumor(P0.05).Conclusions:The expression of KAI1/CD82 is closely related to the invasion and metastasis of LSCC,which can be an important indictor.
Clinical efficacy of oxygen-driven atomizing inhalation of epinephrine in treatment of children with acute laryngitis
SONG Hong-shan
2012, 36(8): 933-934.
Abstract:
Objective:To observe the effects of oxygen-driven aerosol inhalation of epinephrine in treatment for children with acute laryngitis.Methods:Fifty two children with acute laryngitis were randomly divided into the treatment group and the control group(26 in each group).The patients in treatment group were treated by inhalation of epinephrine via oxygen-driven nebulizer,and the patients in the control group were inhalated with budesonide.The symptoms and signs of all cases were observed 4 hours after treatment,and the clinical effects were evaluated.Results:The total cure rates of the treatment group and control group were 84.6% and 73.1% respectively,and the differences was not significant(P0.05).Relieving bark-like cough and inspiratory three depressions signs of treatment group were significantly better than that of the control group(P0.05).Conclusions:Oxygen-driven atomizing inhalation of epinephrine can rapidly improve the symptoms of acute laryngitis including bark-like cough and inspiratory three depressions.
The effects of ultrasonic atomization surface anesthesia with lidocaine on bronchoscopy
SUN Jun
2012, 36(8): 935-936.
Abstract:
Objective:To compare the effects of two kinds of anesthesia on bronchoscopy.Methods:One hundred and twenty patients were randomly divided into group A(60 cases),which were used by ultrasound inhalation method,and group B(60 cases),which were used by throat spray.The oxygen saturation,pulse,heart rate,respiratory rate,cough and adverse reaction rates of memory of two groups were observed before examination and in process of examination and the reexamination rates were investigated after examination.Results:The oxygen saturation of group B was significantly lower than that of group A,while its heart and respiratory rates were significantly higher than that of group A(P0.01).The cough,bad memory and the average consumption amount of drugs of group A were less than that of group B,while its anesthesia effects and reexamination rates were higher than that of group B(P0.01).Conclusions:The ultrasonic atomization surface anesthesia is of good efficacy,short time to achieve effective anesthesia,less medication,less pain of the patient and less interference of the operator,which can ensure the smooth progress of bronchoscopy and be widely used in clinical.
Clinical effects of treatment of lumbar facet joint osteoarthritis with glucosamine hydrochloride
ZHENG Mu-ping, LUO Min-sheng, WANG Jie
2012, 36(8): 937-938.
Abstract:
Objective:To explore the clinical effects of treatment of lumbar facet joint osteoarthritis(LFJOA) with glucosamine hydrochloride(GH).Methods:One hundred and eighty patients with LFJOA were randomly divided into control group,which were treated with Loxoprofen Sodium and treatment group,which were treated with Loxoprofen Sodium at two weeks before treatment and GH for three courses.The effects of two groups were compared.Results:Compared with the control group,the Oswestry scores of treatment group were higher after 3 months(P0.01),and lower after 6 and 12 months(P0.01).Conclusions:Treatment of LFJOA with GH is effective,minor adverse effects,and GH is an effective drug.
Effects of treatment for acute coronary syndrome with fast atrial fibrillation with amiodarone
DAI Zhi-jiang
2012, 36(8): 939-941.
Abstract:
Objective:To observe the effects and safety of intravenous injection amiodarone on acute coronary syndrome(ACS) with fast atrial fibrillation(AF).Methods:Forty-eight cases with ACS with fast AF were treated with intravenous injection of amiodarone,and maintained at 0.5-1.0 mg/min for 0.5-24 hours.The reversion of AF,the ventricular rates,blood pressure and side-effects were observed at 30 min,2 hour and 24 hour after treatment.Results:Compared with pretreatment,36 cases were reverted(the reversion rates as 75%) and the ventricular rates were apparent decline after treatment(P0.01).Systolic blood pressure change was not apparent,but the diastolic blood pressure after treatment was lower than that of pre-treatment(P0.05),The reversion rates of cardiac function with grade Ⅰ and Ⅱ(82.9%) were higher than that of cardiac function with grade Ⅲ and Ⅳ(46.2%)(P0.05).Five cases(10.4%) with sinus bradycardia and 4 cases(8.3%) with low blood pressure after reduction or stopping the drug,which could recover after giving dopamine were observed.Conclusions:Treatment of ACS with fast AF with intravenous injection of amiodarone have higher reversion rates and fewer side-effects.
Treatment for 42 cases with degenerative lumbar instability with pedicle screw fixation combined with interbody fusion
LI Guo-qiang, LIN Yong-xiang
2012, 36(8): 941-943.
Abstract:
Objective:To investigate the clinical effects of treatment degenerative lumbar instability with pedicle screw fixation combined with interbody fusion.Methods:Forty-two patients with degenerative lumbar instability were treated with pedicle screw fixation combined with interbody fusion.Results:All cases were followed up for 6 months to 5 years.The bony fusions and no fixation failure were detected in postoperative 4 to 6 months,and the lower limbs pain were significantly relieved.The excellent in 31 cases,good in 9 cases and fair in 2 cases were confirmed and the excellent and good rate was 95.2%.Conclusions:Pedicle screw fixation combined with interbody fusion is effective way for treating the degenerative lumbar instability.
Clinical analysis of 36 cases with reoperation for thyroid
WANG Xiao-yong, YANG Jing, LI Cheng-hua, WANG Mao
2012, 36(8): 944-946.
Abstract:
Objective:To investigate the reoperation indications of thyroid and prevention of complications.Methods:The clinical data of 36 cases with thyroid reoperation were retrospectively analyzed.Results:Three cases with temporary recurrent laryngeal nerve injury,2 cases with temporary hypoparathyroidism,1 case with chyle leakage and 1 case with bleeding were observed,and the other patients recovered well.Conclusions:The reoperation of thyroid is difficult and has more complications.Preoperative evaluation and careful operation can reduce the occurrence of complications.
Analysis of causes and misdiagnosis of pericardial effusion:a report of 81 cases
LI Hui
2012, 36(8): 946-947.
Abstract:
Objective:To summarize the causes and reasons for misdiagnosis of pericardial effusion.Methods:The clinical data of 81 cases of pericardial effusion during 2002 to 2010 in Lu'an Hospital were analyzed retrospectively.Results:Among the 81 cases of pericardial effusion,19 were induced by tumor(23.4%),16 by tuberculosis(16.0%),11 heart failure(13.6%),9 nonspecific causes(11.1%),7 hypothyroidism(8.6%),5 uremia(6.2%) and 17 other causes or unknown causes(20.1%),misdiagnosis occurred in 9 cases(11.1%).Conclusions:Tumor is the leading cause of pericardial effusion.Tumor-induced pericardial effusion is most easily misdiagnosed as that induced by tuberculosis or nonspecific causes
Clinical analysis of treatment 30 cases with multiple ribs fracture with the shape memory alloy embracing plate
WANG Gang, GAO Feng, LI Xin-ya, YANG Xiao-song, TIAN Cong, WU Ke-song
2012, 36(8): 948-950.
Abstract:
Objective:To evaluate the clinical effects of treatment multiple ribs fracture with the shape memory alloy embracing plate.Methods:The data of treatment 30 cases with multiple ribs fracture with the shape memory alloy embracing plate were analyzed retrospectively.The vital signs and pain degree of all cases were compared before and after treatment.Results:The vital signs of all cases were obviously improved,the heart rate,saturation of blood oxygen and respiratory rate closed to almost normal levels and pain was significantly alleviated(P0.01).Conclusions:The effects of treatment multiple ribs fracture with the shape memory alloy embracing plate are good,which can improve the living quality of patients.
The effects of posterior pedicle fixation system on thoracolumbar fracture
WANG Zheng-jie
2012, 36(8): 950-952.
Abstract:
Objective:To investigate the clinic effects of posterior pedicle fixation system on thoracolumbar fracture.Methods:Sixty patients with thoracolumbar fracture were randomly divided into the observation and control group(30 in each group) according to the surgery serial number.The observation group were treated with posterior pedicle fixation system and the control group were treated with conventional pedicle screw fixation.The heights of anterior and posterior margin of vertebral centrum injuied,Cobb's angle correction,the spinal canal cross-sectional area improved and the spinal nerves injuries of two groups after operation were statistically analyzed.Results:The heights of anterior and posterior margin of vertebral centrum injuried,Cobb's angle,spinal canal cross-sectional area and spinal nerves injuries of two groups were no significantly different(P0.05) at preoperation,and these data were improved to some extent at postoperation and the improvement of the observation were better than that of the control group(P0.05).Conclusions:The clinic effects of treatment of thoracolumbar fracture with posterior pedicle fixation system are good,reliable and less trauma,which is worthy of being widely applied in clinic.
Clinical analysis of nephron-sparing surgery in treatment of 19 cases with incidental renal cell carcinoma
LU Wei-min, JIANG Zheng-gan, WANG Zhi-jin
2012, 36(8): 953-954.
Abstract:
Objective:To observe the clinical effects of nephron-sparing surgery on incidental renal cell carcinoma(RCC).Methods:The data of 19 incidental RCC patients underwent nephron-sparing surgery were retrospectively analyzed.Renal artery of all cases were blocked at lower temperatures.The CT and ultrasound of abdomen,urinalysis and kidney functions were examined per 3 months.Results:The operation of 19 cases were successfully completed and 1 case with secondary bleeding and 1 case with urinary fistulas were found at postoperative.All patients were followed up for 6 to 24 months,no case with local recurrence or distant metastasis was detected.Conclusions:Nephron-sparing surgery is safe and effective way for treatment of incidental RCC patients.
The effects of treatment for refractory postpartum hemorrhage with uterine artery ligation combined with gauze packing in the uterine cavity
CAO Xu, PAN Feng-juan, WANG Chao-jun
2012, 36(8): 955-957.
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Objective:To investigate the effects of treatment for refractory postpartum hemorrhage with uterine artery ligation combined with gauze packing in the uterine cavity.Methods:Thirty-nine patients with refractory postpartum hemorrhage during cesarean section were divided into the control group which were treated with the uterine artery ligation combined with modified B-lynch suture(18 cases) and the observation group which were treated with the uterine artery ligation combined with gauze packing in the uterine cavity(21 cases).The methods,indications,time,results and complications of operation of two groups were observed.Results:Twenty-one patients of the observation group were successfully treated,and their uteruses were retained.The 16 patients' uteruses of the control group were retained except 2 patients with the poor hemostatic effect.The amount of hemorrhage in 24 hours in the observation group was less than that in the control group(P0.01).But there were no significant differences between the two groups about hysterectomy numbers,operation time and puerperal morbidity.Conclusions:The effects of treatment for refractory postpartum hemorrhage with uterine artery ligation combined with gauze packing in the uterine cavity is good.The cure is simple and feasible,less bleeding,no complications and adverse effects and can retain uterus.
Clinical experience of two-way drainage for urinary leakage caused by renal injury
HU Zong-ya
2012, 36(8): 958-959.
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Objective:To explore the clinical characteristics,diagnosis and treatment of urinary leakage with percutaneous drainage and double J stent.Methods:Fifteen cases were treated with percutaneous drainage and double J stent.Results:Through 1-2 years follow-up,renal function of all patients were good.No renal hypertension,hydronephrosis and renal infection were detected in cases with percutaneous drainage and double J stent therapy.Conclusions:According to the degree of urinary leakage,the percutaneous external drainage and double J tube drainage have good curative effect.
Clinical efficacy of locking compression plate fixation in treatment of femoral intertrochanteric fracture
YANG Ling, NIE Lei, SUN Hu-shan
2012, 36(8): 960-961.
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Objective:To investigate the effects of locking compression plate fixation in treatment of intertrochanteric fracture.Methods:Twenty-one cases with femoral intertrochanteric fracture were treated with locking compression plate fixation.Results:The fractures of all cases were recovered after 3-6 months.The complications of nails breakage and internal fixation loosening were not found.The function recovery of hip joint were good and no clear lower limb shortening deformity.Excellent and good effects in 13 and 8 cases were confirmed according to Harris standard.Conclusions:Treatmment of femoral intertrochanteric fracture with locking compression plate fixation is easy to install and fix,which is an effective method of operation with shorter operative time,less bleeding and goog hip joint function recovery.
Clinic analysis of postcholecystectomy syndrome followed laparoscopic and open cholecystectomy
LIAO Heng-jiang, SONG Zai-ru, WANG Jia-lin
2012, 36(8): 962-963.
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Objective:To compare the rate of postcholecystectomy syndrome(PCS) followed laparoscopic and open cholecystectomy.Methods:Two hundred and twenty-nine cases of open cholecystectomy and 139 cases of laparoscopic cholecystectomy were retrospectively analyzed for the PCS rate.Results:There was no significant difference between open cholecystectomy and laparoscopic cholecystectomy for the PCS rate(P0.05).The PCS rate was higher in the patients who accepted cholecystectomy during acute phase when compared with non-acute phase(P0.01).Patients underwent T-tube drainage suffered from a much higher PCS rate when compared with other groups(P0.01).Conclusions:There is no significant difference between open cholecystectomy and laparoscopic cholecystectomy for the PCS rate.Patients in the acute phase and underwent T-tube have from a much higher PCS rate.
Clinical analysis of 46 cases with complexity renal calculi by open surgery method
ZHANG Jian-zhu, LI Qing-wen
2012, 36(8): 964-966.
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Objective:To analyse the efficacy of the open surgery on complexity renal calculi.Methods:The clinical open surgery data of 46 cases with complexity renal calculi were analysed.Twenty-one cases were operated by pelvis incision of renal sinus,renal pelvis combined with renal incision in 9 cases,and renal incision in 16 cases.Results:Average operation time was 135 minutes and renal functions were improved in varying degrees post-operation.The calculi were completely removed in 42 cases,4 cases with residual stones were removed by extracorporeal shock wave lithotripsy,and postoperative bleeding in 2 cases,urinary tract infection in 5 cases and urine leakage in 2 case.All cases were followed up for 3 to 36 months.Two cases with partial renal blood insufficiency and atrophy and 1 case with renovascular hypertension were detected by color Doppler ultrasound scanning.Conclusions:Open surgery is a safe and effective surgical method for treatment complexity renal calculi,and reasonable operation mode is a key for improving the effects of complexity renal calculi.
2012, 36(8): 966-967.
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2012, 36(8): 968-969.
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2012, 36(8): 969-971.
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2012, 36(8): 972-974.
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2012, 36(8): 974-975.
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2012, 36(8): 976-977.
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2012, 36(8): 977-978.
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2012, 36(8): 979-981.
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Etiologic analysis of sputum from patients with pulmonary infection in ICU
WU Qiang, WANG Hua-xue, GUO Pu, ZHENG Sheng-yong, HE Xian-di
2012, 36(8): 981-984.
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Objective:To investigate the distribution and antibiotic resistance of pathogens that cause pulmonary infections among patients in the intensive care unit(ICU),and provide basis for rational selection of clinical drugs.Methods:The clinical date of 1 425 bacterial strains isolated from the sputum of patients with pulmonary infection in the ICU from Aug.2008 to Feb.2012 were retrospectively analyzed and validated exclusively with the CLSI standard.Results:Of the infection pathogens,gram-negative bacteria accounted for 64.8%,gram-positive cocci 19.6% and fungi 15.6%.The common clinical isolates in ICU were Acinetobacter baumannii,Staphylococcus aureus,Pseudomonas aeruginosa,Candida albicans,Klebsiella pneumoniae,Escherichia coli,Staphylococcus epidermidis and Candida glabrata,all of which showed high resistance to the antibiotics except fungi.Conclusions:The pathogen in ICU is diverse.Multidrug resistant strains are the focus of concern.
Model of arrhythmia classification based on fuzzy subordination degree and support vector machine
YANG Shu, ZHU Chao
2012, 36(8): 985-988.
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Objective:To discuss the arrhythmia classification method based on the wave's characteristics by using fuzzy subordination degree and support vector machine(SVM) technology.Methods:The electrocardiosignal of MIT-BIH arrhythmia standard database was pre-processed,and QRS waves were identified and located.Electrocardiosignal was clustered by making use of the similarity of electrocardiosignal waves and having QRS waves as the center.The characteristic parameters were Abstracted from electrocardiosignal and fuzzified to build arrhythmia characteristic parameter set.The model of arrhythmia classification was established using the technology of SVM.Results:The classification performance which was assessed by the MIT-BIH arrhythmia database reached a total accuracy of 97.2%.Conclusions:This algorithm has a high accuracy of classification to the electrocardiosignal of MIT-BIH arrhythmia standard database and is quite practicable.
The study of extraction technology of xinnaozhibaoping
XIA Chao, SUN Xing-hua, LIU Yuan, SHI Jin-cheng
2012, 36(8): 988-989.
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Objective:To study the extraction processes of fructus crataegin,ginkgo biloba L and rheum palmatum L of xinnaozhibaoping.Methods:Medicinal materials were extracted with ethanol and the content of anthraquinones were setted as standard.The extraction technology were optimized through orthogonal design.Results:The heating temperature was the main factor of influence extraction effect,followed by extraction time,extraction times and the solvent multiples were the least affect.Six times of 70% ethanol extracting for 3 times(every time for 1.5 hours) at 70 ℃ was the optimum extraction condition.Conclusions:The optimum xinnaozhibaoping extraction from orthogonal design can effectively improve the content of anthraquinones.
A study of the health status of people in northern Anhui:a report of 10 750 cases
BIAN Guang-zhu, QIN Jing, CHEN Wei, ZHAN Xue-ling
2012, 36(8): 990-992.
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Objective:To investigate the physical health status of the healthy people in northern Anhui so as to take timely scientific and effective control measures.Methods:Ten thousand seven hundred and fifty subjects including employees from the enterprises,civil servants and front-line workers in northern Anhui were measured of the height,blood pressure and body weight;and examinations concerning the internal and exterior parts of the body,ophthalmology,stomatology,otorhinolaryngology as well as the abdominal ultrasound and ECG were also performed.The results were analyzed statistically.Results:The detection rates of highcholesterolemia,highglucose,hypertension,obesity and overweight were high in the healthy population in northern Anhui,accounting for 24.73%,18.20%,12.99% and 8.26%,respectively.The difference was significant among different age groups(P0.05-P0.01).Conclusions: In the region of northern Anhui,people with highcholesterolemia,hypertension,highglucose,obesity and overweight tend to increase.Proper measures should be taken to reduce the risk factors,and the people's poor eating habits should be intervened.It is essential to perform periodical health examination,carry out health education and develop a healthy lifestyle in the people in northern Anhui.
Analysis of the status of medical staff on primary rural preventive health care in Anhui province
FU Lian-guo, WU Xue-sen, CHENG Xian-jin, ZHOU Chun-xian, JIA Xian-jie, LIU Yuan, JIANG Ping-ping, PANG Hong-yang
2012, 36(8): 993-996.
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Objective:To understand the status of medical staff on primary rural health care in Anhui province,and provide the basic reason for improving service capability of rural clinics.Methods:Medical staff was selected according to different economical levels from rural clinics which lied in southern,middle and northern in Anhui province,and the conditions of status,education,satisfaction,working time,and basic knowledge were surveyed using self-questionnaire.Results:The average age of medical staff was 41.54,the ratio of male was 80.69%,the ratio of senior high school education was 68.23%,the average working time in rural clinics was 13.94 years;87.59% medical staff were accepted medical education,and given better reputation,but there were several problems during training;the medical staff had general satisfaction on the condition of work and salary;the ratio of spending on public health services time was little,such as preventive immunity;the pass ratios of basic knowledge test were 36.9%,40.5% and 53.8% in northern,middle,and southern in Anhui province respectively.Conclusions:The medical level of the medical staff in rural clinics should be improved,and their age structures should be better arranged,the roles of the rural clinics should be clear,which need perfect training policies and large government investment.
Perioperative nursing of 93 patients with coronary artery bypass grafting
ZHANG Li-ping, YE Feng-lin, ZHOU Nan, DONG Min, LIU Jing-jing, SHI Chao
2012, 36(8): 997-999.
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Objective:To investigate the perioperative nursing experience of patients with coronary artery bypass grafting(CABG).Methods:Psychological nursing,monitoring blood glucose and blood pressure,improving heart and lung function,preventing angina pectoris,improving myocardial ischemia and protecting lower limb vein were carefully preparated before operation.Maintaining stability of circulatory,strengthening management of respiratory tract and respiratory support and keeping drainage duct open were carried out,meanwhile keeping adequate sedation,monitoring blood glucose,maintaining the balance of water,electrolyte and acid-base,guiding diet,nutrition and nursing limb were implemented after operation.Results:The complications included ventricular fibrillation in 1 case,supraventricular heartbeat over in 8 cases,premature ventricular contraction in 3 cases,intrathoracic hemorrhage in 5 cases,death in 8 cases,counterpulsation after application of intra aortic balloon in 1 case,incision infection in 4 cases and lower extremity deep vein thrombosis in 1 case.The average hospital stay was 28 days.Conclusions:Preoperative full preparation,postoperative monitoring all system,nursing of drainage tube and good health guidance can effectively help patients through the critical time of surgery.
The effects of treatment for neck shoulder pain with position intervention combined with respiratory training after laparoscopic cholecystectomy
JIANG Xia, LI Jun
2012, 36(8): 1000-1002.
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Objective:To investigate the effects of treatment for neck shoulder pain with position intervention combined with respiratory training after laparoscopic cholecystectomy(LC).Methods:One hundred cases with LC were randomly divided into experimental group and control group.Two groups were treated with routinely conventional oxygen 3 hours by 3 L/min oxygen flow.The experimental group were adopted semi-reclining position within 6 hours,who took deep breath at the time of neck shoulder pain,while the control group were adopted horizontal position without pillow,who exercised as early as possible at the time of neck shoulder pain.The incidences and degree of neck shoulder pain of two groups were observed after LC.Results:The incidences of neck shoulder pain of the experimental group(10.0%) were lower than that of the control group(34.0%)(P0.01).The visual analogue scale of experimental group was lower than that of control group at 6,12,24,48 and 72 hours after LC(P0.01).Conclusions:Modified semi-reclining position combined with respiratory training can reduce and relieved the incidence and degree of neck shoulder pain.
2012, 36(8): 1002-1004.
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2012, 36(8): 1004-1006.
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2012, 36(8): 1006-1008.
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2012, 36(8): 1008-1009.
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