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2013 Vol. 38, No. 9
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2013, 37(9): 1073-1076.
Abstract:
ObjectiveTo get the human hes1 gene promoter and to analyze its activity. Methods: With Hela genomic DNA as a template， amplify Hes1 5'flanking sequences with PCr， and use double enzyme and sequence to identify it which the amplified fragment connected with pMD18-T vector.Insert the right one to pGL3-Basic; also identify it with double enzyme and sequence.To sequencingthe right recombinant DNA plasmid transient transfection of cervical cancer cells，using dual luciferase reporter gene detection system to detect the activity of the promoter.Results: Sequence of the human Hes1 promoter，which amplify with PCr， is just the same as its in Gene Pool， also detect its activity with dual luciferase reporter gene detection system. Conclusions: Get the activated human Hes1 gene successfully.
ObjectiveTo get the human hes1 gene promoter and to analyze its activity. Methods: With Hela genomic DNA as a template， amplify Hes1 5'flanking sequences with PCr， and use double enzyme and sequence to identify it which the amplified fragment connected with pMD18-T vector.Insert the right one to pGL3-Basic; also identify it with double enzyme and sequence.To sequencingthe right recombinant DNA plasmid transient transfection of cervical cancer cells，using dual luciferase reporter gene detection system to detect the activity of the promoter.Results: Sequence of the human Hes1 promoter，which amplify with PCr， is just the same as its in Gene Pool， also detect its activity with dual luciferase reporter gene detection system. Conclusions: Get the activated human Hes1 gene successfully.
2013, 37(9): 1077-1080.
Abstract:
ObjectiveTo construct the eukaryotic expression vectors of human wild-type and c.454C T mutant-type vascular endothelial growth factor A( VEGFA) gene. Methods: Human VEGFA mrNA was amplified by reverse transcriptase-polymerase chainreaction( rT-PCr) ， and rT-PCr product was digested by restrictive endonucleases BglⅡ and SalⅠ.The wild type recombinant vector( wild-type pEGFP-VEGFA) was constructed by connecting enzyme digestion product and eukaryotic expression vector pEGFP-N1and identified by BglⅡ and SalⅠ double-enzyme digestion and sequence analysis.The mutant-type recombinant vector ( mutant-type pEGFP-VEGFA) was constructed by overlap extension PCr method and also identified by the above methods.Results: Wild-type and mutant-type pEGFP-VEGFA were all digested into two bands of 4 697 and 1 251 bp， representing the pPEGFP-N1 empty plasmid and VEGFA gene， respectively.Sequencing results showed that the sequence of wild-type pEGFP-VEGFA was identical to GenBank VEGFA accession number NM_001025366.The sequence of mutant-type pEGFP-VEGFA was identical to that of wild-type pEGFP-VEGFA， except that base C was replaced by T at position 454 in the mrNA sequence of the VEGFA gene. Conclusions: The eukaryotic expression vectors of human wild-type and mutant-type VEGFA gene have been successfully constructed，which lays a foundation for the biological function research of VEGFA gene in the future.
ObjectiveTo construct the eukaryotic expression vectors of human wild-type and c.454C T mutant-type vascular endothelial growth factor A( VEGFA) gene. Methods: Human VEGFA mrNA was amplified by reverse transcriptase-polymerase chainreaction( rT-PCr) ， and rT-PCr product was digested by restrictive endonucleases BglⅡ and SalⅠ.The wild type recombinant vector( wild-type pEGFP-VEGFA) was constructed by connecting enzyme digestion product and eukaryotic expression vector pEGFP-N1and identified by BglⅡ and SalⅠ double-enzyme digestion and sequence analysis.The mutant-type recombinant vector ( mutant-type pEGFP-VEGFA) was constructed by overlap extension PCr method and also identified by the above methods.Results: Wild-type and mutant-type pEGFP-VEGFA were all digested into two bands of 4 697 and 1 251 bp， representing the pPEGFP-N1 empty plasmid and VEGFA gene， respectively.Sequencing results showed that the sequence of wild-type pEGFP-VEGFA was identical to GenBank VEGFA accession number NM_001025366.The sequence of mutant-type pEGFP-VEGFA was identical to that of wild-type pEGFP-VEGFA， except that base C was replaced by T at position 454 in the mrNA sequence of the VEGFA gene. Conclusions: The eukaryotic expression vectors of human wild-type and mutant-type VEGFA gene have been successfully constructed，which lays a foundation for the biological function research of VEGFA gene in the future.
2013, 37(9): 1081-1083.
Abstract:
ObjectiveTo observe the effects of reyusan on histologic change of rat with gastrointestinal damp-heat type ulcerative colitis( UC) . Methods: Fifty male SD rats were randomly divided into normal group，model group，high-and low-dose reyusan treatment groups and sulfasalazine( SASP) treatment group.The gastrointestinal damp-heat type UC model rats were established by high fat diet，white spirit damp-heat environment and trinitro-benzene-sulfonic acid.The damage index of rats colon mucosa was observed 15 days after drug administration.Results: Compared with the model group， the damage index of rat colon mucosa in high-dose reyusan and SASP treatment group were significantly low( P 0.01) .The difference of the damage index between low-dose reyusan treatment and model group had no statistical significance( P 0.05) .The damage index of SASP treatent group was lower than that in low-dose reyusan treatment group( P 0.05) ，but higher than that in the model group( P 0.05) . Conclusions: reyusan can significantly improve the colon mucosa damage of rat with gastrointestinal damp-heat type UC and promote ulcer repair，which has good therapy effect
ObjectiveTo observe the effects of reyusan on histologic change of rat with gastrointestinal damp-heat type ulcerative colitis( UC) . Methods: Fifty male SD rats were randomly divided into normal group，model group，high-and low-dose reyusan treatment groups and sulfasalazine( SASP) treatment group.The gastrointestinal damp-heat type UC model rats were established by high fat diet，white spirit damp-heat environment and trinitro-benzene-sulfonic acid.The damage index of rats colon mucosa was observed 15 days after drug administration.Results: Compared with the model group， the damage index of rat colon mucosa in high-dose reyusan and SASP treatment group were significantly low( P 0.01) .The difference of the damage index between low-dose reyusan treatment and model group had no statistical significance( P 0.05) .The damage index of SASP treatent group was lower than that in low-dose reyusan treatment group( P 0.05) ，but higher than that in the model group( P 0.05) . Conclusions: reyusan can significantly improve the colon mucosa damage of rat with gastrointestinal damp-heat type UC and promote ulcer repair，which has good therapy effect
2013, 37(9): 1084-1086.
Abstract:
ObjectiveTo evaluate the effects of prophylactic cranial irradiation( PCI) on the survival and brain metastatic rates in patients with limited small-cell lung cancer( SCLC) after complete remission. Methods: Fourty-nine patients with limited SCLC after complete remission treated with chemoradiotherapy were randomly divided into PCI group( 25 cases) and control group( 24 cases) .The PCI group were irradiated at the dose of 25 Gy; the control group didn't receive PCI.The rate of brain metastases and the 1，3，5-year survival rates were assessed.Results: The incidence of brain metastasis of PCI group and control were 12.0% and 41.7%，respectively， the difference of which was statistically significant( P 0.05) .The 1，3 and 5 years survival rates in PCI group were 76.0%， 32.0% and 20.0%，respectively.The 1，3 and 5 years survival rates in control were 58.3%，20.8% and 12.5%，respectively.The differences of survival rates between two groups were not statistically significant( P 0.05) . Conclusions: PCI can decrease the incidence of brain metastasis of patients with limited SCLC.
ObjectiveTo evaluate the effects of prophylactic cranial irradiation( PCI) on the survival and brain metastatic rates in patients with limited small-cell lung cancer( SCLC) after complete remission. Methods: Fourty-nine patients with limited SCLC after complete remission treated with chemoradiotherapy were randomly divided into PCI group( 25 cases) and control group( 24 cases) .The PCI group were irradiated at the dose of 25 Gy; the control group didn't receive PCI.The rate of brain metastases and the 1，3，5-year survival rates were assessed.Results: The incidence of brain metastasis of PCI group and control were 12.0% and 41.7%，respectively， the difference of which was statistically significant( P 0.05) .The 1，3 and 5 years survival rates in PCI group were 76.0%， 32.0% and 20.0%，respectively.The 1，3 and 5 years survival rates in control were 58.3%，20.8% and 12.5%，respectively.The differences of survival rates between two groups were not statistically significant( P 0.05) . Conclusions: PCI can decrease the incidence of brain metastasis of patients with limited SCLC.
The application of thoracoscopy and laparoscopy combined with Mckeown in esophageal cancer operation
2013, 37(9): 1086-1088.
Abstract:
ObjectiveTo explore the feasibility of thoracoscopy and laparoscopy combined with Mckeown in esophageal cancer operation. Methods: Eight cases with esophageal cancer( including superior segment in 1 case，middle segment in 5 cases and inferior segment in 2 cases) were treated with thoracoscopy and laparoscopy combined with Mckeown.Mediastinal lymph nodes of all cases were dissected in thoracic segment of the esophagus using thoracoscopy in prone position of left half.Gastroesophageal anastomosis in left neck of all cases were implemented using laparoscopy in supine postion Results: All operations were successful，no conversion to open surgery and death during perioperative period were found.The operation time，blood loss，number of dissected lymph nodes and postoperative hospital stay were 240 to 400 minutes， 120 to 420 ml，4 to 22 and 14 to 19 days， respectively.One case with respiratory failure was found，who cured after the breathing machine auxiliary treatment.One case with hoarseness was found.All patients were followed up for 2 to 11 months and survival. Conclusions: The thoracoscopy and laparoscopy combined with Mckeown for treating esophageal cancer is safe and feasible，which is worthy of being widely applied in clinic.
ObjectiveTo explore the feasibility of thoracoscopy and laparoscopy combined with Mckeown in esophageal cancer operation. Methods: Eight cases with esophageal cancer( including superior segment in 1 case，middle segment in 5 cases and inferior segment in 2 cases) were treated with thoracoscopy and laparoscopy combined with Mckeown.Mediastinal lymph nodes of all cases were dissected in thoracic segment of the esophagus using thoracoscopy in prone position of left half.Gastroesophageal anastomosis in left neck of all cases were implemented using laparoscopy in supine postion Results: All operations were successful，no conversion to open surgery and death during perioperative period were found.The operation time，blood loss，number of dissected lymph nodes and postoperative hospital stay were 240 to 400 minutes， 120 to 420 ml，4 to 22 and 14 to 19 days， respectively.One case with respiratory failure was found，who cured after the breathing machine auxiliary treatment.One case with hoarseness was found.All patients were followed up for 2 to 11 months and survival. Conclusions: The thoracoscopy and laparoscopy combined with Mckeown for treating esophageal cancer is safe and feasible，which is worthy of being widely applied in clinic.
2013, 37(9): 1089-1092.
Abstract:
ObjectiveTo investigate the subjective memory impairment ( SMI ) in prodromal stage of amnestic mild cognitive impairment( aMCI) and the clinical value of P300 of event-related potentials in early diagnosis and evaluation of Alzheimer's disease.Methods: The cognitive function of the SMI group，aMCI group and control group ( 20 cases each group ) were assessed using multidimensional neuropsychological testing， the event-related potentials of three groups were detected.The change characteristics and differences of P300 between three groups were analysed.Results: The AVMT-delay memory recall，AVMT － immediate memory and CDT in SMI group scores were higher than the aMCI group and the control group( P 0.05 － P 0.01) ，but there was no significant difference between the aMCI group and the control group( P 0.05) ; the level of VFT in SMI and aMCI group were significantly higher than the control group ( P 0.01) ， the VFT in SMI group and the aMCI group showed no statistical difference ( P 0.05) .The connection testing，DS and CFT copying score test in the three groups had no statistical difference ( P 0.05) . Conclusions: The neurophysiological testing has important clinical value in early diagnosis of aMCI and SMI in prodromal stage，but P300 testing has no value for SMI and aMCI clinical diagnosis.
ObjectiveTo investigate the subjective memory impairment ( SMI ) in prodromal stage of amnestic mild cognitive impairment( aMCI) and the clinical value of P300 of event-related potentials in early diagnosis and evaluation of Alzheimer's disease.Methods: The cognitive function of the SMI group，aMCI group and control group ( 20 cases each group ) were assessed using multidimensional neuropsychological testing， the event-related potentials of three groups were detected.The change characteristics and differences of P300 between three groups were analysed.Results: The AVMT-delay memory recall，AVMT － immediate memory and CDT in SMI group scores were higher than the aMCI group and the control group( P 0.05 － P 0.01) ，but there was no significant difference between the aMCI group and the control group( P 0.05) ; the level of VFT in SMI and aMCI group were significantly higher than the control group ( P 0.01) ， the VFT in SMI group and the aMCI group showed no statistical difference ( P 0.05) .The connection testing，DS and CFT copying score test in the three groups had no statistical difference ( P 0.05) . Conclusions: The neurophysiological testing has important clinical value in early diagnosis of aMCI and SMI in prodromal stage，but P300 testing has no value for SMI and aMCI clinical diagnosis.
2013, 37(9): 1093-1095.
Abstract:
ObjectiveTo explore the value of electronic bronchoscope in the diagnosis of atelectasis. Methods: The features of electronic bronchoscope， the causes and location of disease and age of patients of 298 cases with atelectasis were comprehensively analyzed.Results: Among 298 patients with atelectasis， lung cancer in 199 cases， inflammation in 61 cases， tuberculosis in 19 cases，foreign bodies in 5 cases， aspergillus in 3 cases， sputum bolt in 3 cases，Wegener's granulomatosis in 1 case and no clear causes in 7 cases were found.Two hundred and ninty one cases were diagnosed， the diagnostic rate was 97.65%.The incidence rate of right lung atelectasis was significantly higher than that in left lung，upper lobe atelectasis rather than under the leaves ( P 0.01) .The incidence of lung cancer in elderly people( more than 40 years) were significantly higher than that in young people( less than or equal to 40years) .The incidences of inflammation and tuberculosis in young were higher than those in elderly people( P 0.05 to P 0.01) . Conclusions: It is important of electronic bronchoscope to diagnose the cause of atelectasis.
ObjectiveTo explore the value of electronic bronchoscope in the diagnosis of atelectasis. Methods: The features of electronic bronchoscope， the causes and location of disease and age of patients of 298 cases with atelectasis were comprehensively analyzed.Results: Among 298 patients with atelectasis， lung cancer in 199 cases， inflammation in 61 cases， tuberculosis in 19 cases，foreign bodies in 5 cases， aspergillus in 3 cases， sputum bolt in 3 cases，Wegener's granulomatosis in 1 case and no clear causes in 7 cases were found.Two hundred and ninty one cases were diagnosed， the diagnostic rate was 97.65%.The incidence rate of right lung atelectasis was significantly higher than that in left lung，upper lobe atelectasis rather than under the leaves ( P 0.01) .The incidence of lung cancer in elderly people( more than 40 years) were significantly higher than that in young people( less than or equal to 40years) .The incidences of inflammation and tuberculosis in young were higher than those in elderly people( P 0.05 to P 0.01) . Conclusions: It is important of electronic bronchoscope to diagnose the cause of atelectasis.
2013, 37(9): 1096-1098,1102.
Abstract:
ObjectiveTo investigate the clinical curative effects， safety and immune function influence of oxaliplatin combined with capecitabine in the treatment of patients with gastric cancer. Methods: Fifty-two patients with gastric cancer were randomly divided into treatment group and control group( 26 cases each group) .The control group were treated with oxaliplatin combined with 5-fluorouracil and calcium folinate.the treatment group were treated with oxaliplatin combined with capecitabine.The curative effects， levels of T cell subgroup and incidence of adverse reactions of two groups were compared.Results: The total effective rates of the control group and treatment group were 61.54% and 65.38%， the difference of which had no statistical significance( P 0.05) .Compared with before chemotherapy， the levels of CD3 + and CD4 + of two groups decreased after chemotherapy and 2 days in chemotherapy( P 0.05 to P 0.01) .The differences of the levels of CD3 + after chemotherapy and CD4 + after chemotherapy and 2 days in chemotherapy in two groups had statistical significance( P 0.05 to P 0.01) .The levels of CD8 + in two groups did not obviously change before and after chemotherapy， the difference of which had no statistical significance ( P 0.05) .The incidence of nausea and vomiting，hand-foot syndrome and granulocyte declining in treatment group were lower than those in control group( P 0.05 to P 0.01) . Conclusions:Oxaliplatin combined with capecitabine in the treatment of patients with gastric cancer is good effects，high safety and little influence on immunity，which can protect the T cell subgroup， conducive to the rehabilitation of patients，be worthy of being widely applied in clinic.
ObjectiveTo investigate the clinical curative effects， safety and immune function influence of oxaliplatin combined with capecitabine in the treatment of patients with gastric cancer. Methods: Fifty-two patients with gastric cancer were randomly divided into treatment group and control group( 26 cases each group) .The control group were treated with oxaliplatin combined with 5-fluorouracil and calcium folinate.the treatment group were treated with oxaliplatin combined with capecitabine.The curative effects， levels of T cell subgroup and incidence of adverse reactions of two groups were compared.Results: The total effective rates of the control group and treatment group were 61.54% and 65.38%， the difference of which had no statistical significance( P 0.05) .Compared with before chemotherapy， the levels of CD3 + and CD4 + of two groups decreased after chemotherapy and 2 days in chemotherapy( P 0.05 to P 0.01) .The differences of the levels of CD3 + after chemotherapy and CD4 + after chemotherapy and 2 days in chemotherapy in two groups had statistical significance( P 0.05 to P 0.01) .The levels of CD8 + in two groups did not obviously change before and after chemotherapy， the difference of which had no statistical significance ( P 0.05) .The incidence of nausea and vomiting，hand-foot syndrome and granulocyte declining in treatment group were lower than those in control group( P 0.05 to P 0.01) . Conclusions:Oxaliplatin combined with capecitabine in the treatment of patients with gastric cancer is good effects，high safety and little influence on immunity，which can protect the T cell subgroup， conducive to the rehabilitation of patients，be worthy of being widely applied in clinic.
2013, 37(9): 1099-1102.
Abstract:
ObjectiveTo compare the effects of the upper，middle and lower kidney calyx route in the treatment of kidney and upper ureteral calculi through percutaneous nephrolithotomy( PCNL) . Methods: Three hundred and ninty-two cases with kidney and upper ureteral calculi were treated with PCNL， and divided into the upper renal calyx calculi or pelvic stones， lower renal calyx calculi， antler shape stone and upper ureteral calculi( complicating with or without kidney stone) group.The first period calculi completely clearance and puncture success rate，and operation time of the upper，middle and lower kidney calyx route were compared.Results: The first period calculi completely clearance rate and operation time of the upper renal calyx calculi or pelvic stones group through the upper and middle and lower kidney calyx route were 89.4% ＆ 95.1% and( 77.76 5.04) ＆( 81.09 4.14) minutes， respectively.Their differences had statistical or no statistical significance( P 0.05 and P 0.01) .The first period calculi completely clearance rate of the lower renal calyx calculi group through the upper and middle and lower kidney calyx route were 90.9% and 80.0%， respectively，which had no statistical significance( P = 0.572) ， the operation time were( 75.32 9.23) and( 84.5 15.27) minutes， respectively，which had statistical significance( P 0.05) .The first period calculi completely clearance rate and operation time of the antler shape stone group through the upper and middle and lower kidney calyx route were 88.2% ＆ 72.3% and( 118.69 3.28) ＆( 141.08 4.78)minutes， respectively.Their differences had statistical significance ( P 0.05 and P 0.01 ) .The first period calculi completely clearance rate and operation time of the upper ureteral calculi group through the upper and middle and lower kidney calyx route were89.7% ＆ 64.0% and( 98.98 6.12) ＆( 115.56 6.98) minutes， respectively.Their differences had statistical significance( P 0.05 and P 0.01) .The puncture success rates of all cases are 100%. Conclusions: The calculi clearance rates of the antler shape stone and upper ureteral calculi through the upper kidney calyx route is higher， and its operation time is shorter.
ObjectiveTo compare the effects of the upper，middle and lower kidney calyx route in the treatment of kidney and upper ureteral calculi through percutaneous nephrolithotomy( PCNL) . Methods: Three hundred and ninty-two cases with kidney and upper ureteral calculi were treated with PCNL， and divided into the upper renal calyx calculi or pelvic stones， lower renal calyx calculi， antler shape stone and upper ureteral calculi( complicating with or without kidney stone) group.The first period calculi completely clearance and puncture success rate，and operation time of the upper，middle and lower kidney calyx route were compared.Results: The first period calculi completely clearance rate and operation time of the upper renal calyx calculi or pelvic stones group through the upper and middle and lower kidney calyx route were 89.4% ＆ 95.1% and( 77.76 5.04) ＆( 81.09 4.14) minutes， respectively.Their differences had statistical or no statistical significance( P 0.05 and P 0.01) .The first period calculi completely clearance rate of the lower renal calyx calculi group through the upper and middle and lower kidney calyx route were 90.9% and 80.0%， respectively，which had no statistical significance( P = 0.572) ， the operation time were( 75.32 9.23) and( 84.5 15.27) minutes， respectively，which had statistical significance( P 0.05) .The first period calculi completely clearance rate and operation time of the antler shape stone group through the upper and middle and lower kidney calyx route were 88.2% ＆ 72.3% and( 118.69 3.28) ＆( 141.08 4.78)minutes， respectively.Their differences had statistical significance ( P 0.05 and P 0.01 ) .The first period calculi completely clearance rate and operation time of the upper ureteral calculi group through the upper and middle and lower kidney calyx route were89.7% ＆ 64.0% and( 98.98 6.12) ＆( 115.56 6.98) minutes， respectively.Their differences had statistical significance( P 0.05 and P 0.01) .The puncture success rates of all cases are 100%. Conclusions: The calculi clearance rates of the antler shape stone and upper ureteral calculi through the upper kidney calyx route is higher， and its operation time is shorter.
2013, 37(9): 1103-1104,1107.
Abstract:
ObjectiveTo explore the effects of different dosage atorvastation on the levels of inflammatory factors in patients with acute coronary syndrome( ACS) after percutaneous coronary intervention( PCI) . Methods: One hundred and ten patients with ACS after PCI were divided into experimental group and control group( 55 cases each group) .Inaddition to conventional therapy， the control group were treated with 10 mg /d of atorvastation by oral， the experimental group were treated with 40 mg /d of atorvastation by oral form before operation.The serum levels of C-reactive protein( CrP) ， troponin I( cTnI) ， fiber Fib( FIB) and D-dimer( DD) in two groups were measured on the day of operation and postoperative two weeks.Results: The differences of CrP， cTnI，FIB and DD levels in two group had no statistical significance before operation( P 0.05) .Compared with before operation， the levels of CrP，cTnI，FIB and DD in control group were increased after PCI( P 0.05 to P 0.01) ，but the four indexes change in the experimental group were not obvious( P 0.05) .The levels of CrP， cTnI and FIB in control group were higher than those in experimental group after operation( P 0.01) . Conclusions: PCI can elevate the levels of CrP， cTnI，FIB and DD.Atorvastation can help to control the inflammatory factors levels，reduce inflammatory reaction after PCI.
ObjectiveTo explore the effects of different dosage atorvastation on the levels of inflammatory factors in patients with acute coronary syndrome( ACS) after percutaneous coronary intervention( PCI) . Methods: One hundred and ten patients with ACS after PCI were divided into experimental group and control group( 55 cases each group) .Inaddition to conventional therapy， the control group were treated with 10 mg /d of atorvastation by oral， the experimental group were treated with 40 mg /d of atorvastation by oral form before operation.The serum levels of C-reactive protein( CrP) ， troponin I( cTnI) ， fiber Fib( FIB) and D-dimer( DD) in two groups were measured on the day of operation and postoperative two weeks.Results: The differences of CrP， cTnI，FIB and DD levels in two group had no statistical significance before operation( P 0.05) .Compared with before operation， the levels of CrP，cTnI，FIB and DD in control group were increased after PCI( P 0.05 to P 0.01) ，but the four indexes change in the experimental group were not obvious( P 0.05) .The levels of CrP， cTnI and FIB in control group were higher than those in experimental group after operation( P 0.01) . Conclusions: PCI can elevate the levels of CrP， cTnI，FIB and DD.Atorvastation can help to control the inflammatory factors levels，reduce inflammatory reaction after PCI.
2013, 37(9): 1105-1107.
Abstract:
ObjectiveTo investigate the clinical effects of intra-arotic balloon counterpulsation in the treatment of acute massive myocardial infarction complicated with cardiogenic shock. Methods: Eleven patients with acute myocardial infarction and cardio genic shock after intra-arotic balloon pump( IABP) therapy.Results: The hemodynamics in 8 patients were stable，3 cases died of pump failure. Conclusions: IABP can effectively improve hemodynamics，which is good for improving the survival rate of myocardial infarction patients
ObjectiveTo investigate the clinical effects of intra-arotic balloon counterpulsation in the treatment of acute massive myocardial infarction complicated with cardiogenic shock. Methods: Eleven patients with acute myocardial infarction and cardio genic shock after intra-arotic balloon pump( IABP) therapy.Results: The hemodynamics in 8 patients were stable，3 cases died of pump failure. Conclusions: IABP can effectively improve hemodynamics，which is good for improving the survival rate of myocardial infarction patients
2013, 37(9): 1108-1111.
Abstract:
ObjectiveTo explore the expression of KAI1 and epithelia-cadherin( E-cad) in infiltrating cervical carcinoma( ICC) and their clinical significance. Methods: The expressions of KAI1 and E-cad were examined by immunohistochemistry containing 76 specimens of ICC tissues，30 specimens of cervical intraepithelial neoplasia( CIN) ，and 20 specimens of normal cervical epithelium( NCE) .Results: The positive rates of KAI1 and E-cad in ICC tissues，CIN tissues， and NCE tissue were 42.1%， 70.0%， 100% and 40.8%， 63.3%， 100.0%， respectively.There was a significant difference between the two groups( P 0.01) .The expressions of KAI1 and E-cad were significantly associated with grades of tumor， lymph node metastasis，pathological-TNM stages( P 0.05 to P 0.01) . And there was a positive relationship between KAI1 and E-cad expression( P 0.01) . Conclusions: The low or loss expression of KAI1 and E-cad may promote ICC progression，development and metastasis; the combined detection of KAI1 and E-cad has an important role in predicting the progression and prognosis of ICC.
ObjectiveTo explore the expression of KAI1 and epithelia-cadherin( E-cad) in infiltrating cervical carcinoma( ICC) and their clinical significance. Methods: The expressions of KAI1 and E-cad were examined by immunohistochemistry containing 76 specimens of ICC tissues，30 specimens of cervical intraepithelial neoplasia( CIN) ，and 20 specimens of normal cervical epithelium( NCE) .Results: The positive rates of KAI1 and E-cad in ICC tissues，CIN tissues， and NCE tissue were 42.1%， 70.0%， 100% and 40.8%， 63.3%， 100.0%， respectively.There was a significant difference between the two groups( P 0.01) .The expressions of KAI1 and E-cad were significantly associated with grades of tumor， lymph node metastasis，pathological-TNM stages( P 0.05 to P 0.01) . And there was a positive relationship between KAI1 and E-cad expression( P 0.01) . Conclusions: The low or loss expression of KAI1 and E-cad may promote ICC progression，development and metastasis; the combined detection of KAI1 and E-cad has an important role in predicting the progression and prognosis of ICC.
2013, 37(9): 1111-1113.
Abstract:
ObjectiveTo explore the application of individual operation and perioperation period processing in the treatment of gastric cancer complicated with portal hypertension( PHT) . Methods: The clinical data of 18 patients with gastric cancer complicated with PHT treated with individual treatment were retrospectively analysed.Seventeen cases were treated with D2 radical operation，1 case was treated with palliative resection，6 cases were treated with splenectomy combined with pericardial devascularization，and 8 cases were treated with splenectomy.Results: Ascites in 16 cases， intra-abdominal hemorrhage in 2 cases， intra-abdominal abscess in 1 case，incision infection in 1 cases and wound dehiscence in 1 case were found.All patients recovered after active treatment. Conclusions: The operation， treatment and postoperative complications in patients with gastric cancer with PHT are complex，difficult and more.The individual operation and perioperation period processing in the treatment of gastric cancer complicated with PHT are feasible.
ObjectiveTo explore the application of individual operation and perioperation period processing in the treatment of gastric cancer complicated with portal hypertension( PHT) . Methods: The clinical data of 18 patients with gastric cancer complicated with PHT treated with individual treatment were retrospectively analysed.Seventeen cases were treated with D2 radical operation，1 case was treated with palliative resection，6 cases were treated with splenectomy combined with pericardial devascularization，and 8 cases were treated with splenectomy.Results: Ascites in 16 cases， intra-abdominal hemorrhage in 2 cases， intra-abdominal abscess in 1 case，incision infection in 1 cases and wound dehiscence in 1 case were found.All patients recovered after active treatment. Conclusions: The operation， treatment and postoperative complications in patients with gastric cancer with PHT are complex，difficult and more.The individual operation and perioperation period processing in the treatment of gastric cancer complicated with PHT are feasible.
2013, 37(9): 1114-1115,1118.
Abstract:
ObjectiveTo observe the result of two methods in treatment of pterygium. Methods: A total of 95 patients( 112 eyes) were divided into two groups randomly.Forty-seven patients ( 57 eyes) ( stem cell group) were treated with compound excision which mitomycin C and autologous corneal Limbal stem cell transplantation with conjuctival flap were used.Forty-eight patients( 55 eyes)( amnion group) were treated with mitomycin C and amniotic transplantation.After 6 － 18 months follow-up， the postoperative recurrence and complication of two groups were analyzed.Results: Three cases reoccurred and the recurrence rate was 5.3 % in stem cell group.Thirteen cases reoccurred and the recurrence rate was 23.6 % in amnion group.There was statistical difference in the recurrence between the two groups( P 0.01) . Conclusions: The antologous corneal limbal stem cell transplantation with conjunctiva flap can decrease the recurrent rate， and it is safe， effective， reliable for the treatment of pterygium
ObjectiveTo observe the result of two methods in treatment of pterygium. Methods: A total of 95 patients( 112 eyes) were divided into two groups randomly.Forty-seven patients ( 57 eyes) ( stem cell group) were treated with compound excision which mitomycin C and autologous corneal Limbal stem cell transplantation with conjuctival flap were used.Forty-eight patients( 55 eyes)( amnion group) were treated with mitomycin C and amniotic transplantation.After 6 － 18 months follow-up， the postoperative recurrence and complication of two groups were analyzed.Results: Three cases reoccurred and the recurrence rate was 5.3 % in stem cell group.Thirteen cases reoccurred and the recurrence rate was 23.6 % in amnion group.There was statistical difference in the recurrence between the two groups( P 0.01) . Conclusions: The antologous corneal limbal stem cell transplantation with conjunctiva flap can decrease the recurrent rate， and it is safe， effective， reliable for the treatment of pterygium
2013, 37(9): 1116-1118.
Abstract:
ObjectiveTo evaluate the clinical effects of laser combined with iodized lecithin tablets in the treatment of central serous chorioretinopathy( CSC) . Methods: Fifty-five patients( 57 eyes) with CSC( fundus leakage in more than 500 m from the center of central fovea of macula) were randomly divided into treatment group and control group.The control group( 26 cases，31 eyes) were treated with 532 laser photocoagulation.The treatment group( 29 cases， 31 eyes) were treated with 532 laser photocoagulation combined with iodized lecithin tablets by oral.The vision， fundus and fluorescence fundus angiography( FFA) of two groups were observed 2，4 weeks and 3 months after treatment.Results: The vision of two groups were significantly improved after treatment( P 0.01) ， the vision of treatment group were significantly higher than those in control group 2 and 4 weeks after treatment( P 0.01) ， the difference of vision in two group was not statistical significance 3 months after treatment( P 0.05) .The difference of cure rate between two groups had no statistical significance( P 0.05) .The disappearance rate of self-conscious symptom in treatment group was higher than that in control group in 3 months after treatment ( P 0.01 ) .The difference of reoccurrence rate between two groups had no statistical significance( P 0.05) . Conclusions: The 532 laser combined with iodized lecithin tablets for treating CSC is safe and effective，which can shorten the course of disease and strengthen the repairing effects of non-treatment area in retina.
ObjectiveTo evaluate the clinical effects of laser combined with iodized lecithin tablets in the treatment of central serous chorioretinopathy( CSC) . Methods: Fifty-five patients( 57 eyes) with CSC( fundus leakage in more than 500 m from the center of central fovea of macula) were randomly divided into treatment group and control group.The control group( 26 cases，31 eyes) were treated with 532 laser photocoagulation.The treatment group( 29 cases， 31 eyes) were treated with 532 laser photocoagulation combined with iodized lecithin tablets by oral.The vision， fundus and fluorescence fundus angiography( FFA) of two groups were observed 2，4 weeks and 3 months after treatment.Results: The vision of two groups were significantly improved after treatment( P 0.01) ， the vision of treatment group were significantly higher than those in control group 2 and 4 weeks after treatment( P 0.01) ， the difference of vision in two group was not statistical significance 3 months after treatment( P 0.05) .The difference of cure rate between two groups had no statistical significance( P 0.05) .The disappearance rate of self-conscious symptom in treatment group was higher than that in control group in 3 months after treatment ( P 0.01 ) .The difference of reoccurrence rate between two groups had no statistical significance( P 0.05) . Conclusions: The 532 laser combined with iodized lecithin tablets for treating CSC is safe and effective，which can shorten the course of disease and strengthen the repairing effects of non-treatment area in retina.
2013, 37(9): 1119-1120.
Abstract:
ObjectiveTo investigate the effects of compound lidocaine cream on the tolerance of indwelling catheter in male patients with general anesthesia. Methods: Eighty male patients with general anesthesia were randomly divided into control group and study group， 40 cases in each group.The control group and study group were treated with conventional catheter and compound lidocaine cream swearing catheter， respectively.The hemodynamics during anesthesia recovery， the catheter tolerance and agitation in two groups were observed.Results: The blood pressure and heart rate during anesthesia recovery in control group were significantly higher than those in study group( P 0.01) .The well tolerated rate of catheter in control group( 10.0%) was significantly less than that in study group( 75.0%) ( P 0.01) . Conclusions: Compound lidocaine cream can significantly improve the tolerance of indwelling catheter，and effectively reduce the incidence of agitation caused by urinary pain in male patients after general anesthesia.
ObjectiveTo investigate the effects of compound lidocaine cream on the tolerance of indwelling catheter in male patients with general anesthesia. Methods: Eighty male patients with general anesthesia were randomly divided into control group and study group， 40 cases in each group.The control group and study group were treated with conventional catheter and compound lidocaine cream swearing catheter， respectively.The hemodynamics during anesthesia recovery， the catheter tolerance and agitation in two groups were observed.Results: The blood pressure and heart rate during anesthesia recovery in control group were significantly higher than those in study group( P 0.01) .The well tolerated rate of catheter in control group( 10.0%) was significantly less than that in study group( 75.0%) ( P 0.01) . Conclusions: Compound lidocaine cream can significantly improve the tolerance of indwelling catheter，and effectively reduce the incidence of agitation caused by urinary pain in male patients after general anesthesia.
2013, 37(9): 1121-1122,1126.
Abstract:
ObjectiveTo explore the vascular treatment in retroperitoneoscopic resection of adrenal tumor. Methods: The adrenal tumors in 32 patients were resected by retroperitoneoscopy.The adrenal gland and tumors were dissociated above the kidney during the operation， the superior，middle and inferior adrenal arteries were treated with ultrasonic knife and titanium clips， the adrenal central veins were dissociated and ligatured( the right adrenal central vein was dissociated along the surface of the inferior vena cava， the left adrenal central vein was dissociated along the edge of the adrenal glands and the upper pole of the kidney) .The adrenal and the tumor were completely resected.Results: All operations in 32 cases were successful， the amount of bleeding loss was 10 to 150 ml.The right adrenal central vein of 1 case poured into the right side of the inferior vena cava.The right adrenal central vein of 1 case divided into two branches， the head and foot side of which were thin and thick，and poured into the right hepatic vein and inferior vena cava，respectively. Conclusions: Mastering the vascular anatomy and variations of adrenal glands and correct treatment can effectively prevent the intraoperative bleeding in retroperitoneoscopic resection of adrenal tumor.
ObjectiveTo explore the vascular treatment in retroperitoneoscopic resection of adrenal tumor. Methods: The adrenal tumors in 32 patients were resected by retroperitoneoscopy.The adrenal gland and tumors were dissociated above the kidney during the operation， the superior，middle and inferior adrenal arteries were treated with ultrasonic knife and titanium clips， the adrenal central veins were dissociated and ligatured( the right adrenal central vein was dissociated along the surface of the inferior vena cava， the left adrenal central vein was dissociated along the edge of the adrenal glands and the upper pole of the kidney) .The adrenal and the tumor were completely resected.Results: All operations in 32 cases were successful， the amount of bleeding loss was 10 to 150 ml.The right adrenal central vein of 1 case poured into the right side of the inferior vena cava.The right adrenal central vein of 1 case divided into two branches， the head and foot side of which were thin and thick，and poured into the right hepatic vein and inferior vena cava，respectively. Conclusions: Mastering the vascular anatomy and variations of adrenal glands and correct treatment can effectively prevent the intraoperative bleeding in retroperitoneoscopic resection of adrenal tumor.
2013, 37(9): 1123-1126.
Abstract:
ObjectiveTo explore the effects of percutaneous transhepatic biliary drainage( PTBD) combined with biliary stent in the treatment of malignant upper biliary tract obstruction. Methods: Stents were implanted into 12 patients by unilateral or bilateral puncture.The single stent was implanted into the ductuli hepaticus communis in 7 cases.The stents were implanted into the left and right hepatic duct through bilateral hepatic duct puncture in 3 cases at the same time.The stents were implanted into between the 1eft and right hepatic duct and between the hepatic duct and the common bile duct through unibilateral hepatic duct puncture in 2 cases.results: Twelve operations were successful.The jaundice of all patients alleviated or disappeared obviously after implantation.After 7 dtotal bilirubin，direct bilirubin，alkaline phosphatase，alanine aminotransferase，-glutamine transaminase levels before treatment difference was statistically significant( P 0.05 － P 0.01) .One case with stent obstruction was found in 4 months after operation，who were treated with secondary intervention.One case with duodenal obstruction was found in 6 months after implanting sent into biliary tract，who was treated with stent in duodenum. Conclusions: Implanting stent into different bile duct for treating malignant upper biliary tract obstruction is safe， reliable and good effects.
ObjectiveTo explore the effects of percutaneous transhepatic biliary drainage( PTBD) combined with biliary stent in the treatment of malignant upper biliary tract obstruction. Methods: Stents were implanted into 12 patients by unilateral or bilateral puncture.The single stent was implanted into the ductuli hepaticus communis in 7 cases.The stents were implanted into the left and right hepatic duct through bilateral hepatic duct puncture in 3 cases at the same time.The stents were implanted into between the 1eft and right hepatic duct and between the hepatic duct and the common bile duct through unibilateral hepatic duct puncture in 2 cases.results: Twelve operations were successful.The jaundice of all patients alleviated or disappeared obviously after implantation.After 7 dtotal bilirubin，direct bilirubin，alkaline phosphatase，alanine aminotransferase，-glutamine transaminase levels before treatment difference was statistically significant( P 0.05 － P 0.01) .One case with stent obstruction was found in 4 months after operation，who were treated with secondary intervention.One case with duodenal obstruction was found in 6 months after implanting sent into biliary tract，who was treated with stent in duodenum. Conclusions: Implanting stent into different bile duct for treating malignant upper biliary tract obstruction is safe， reliable and good effects.
2013, 37(9): 1127-1129.
Abstract:
ObjectiveTo evaluate the effects of total mesorectal excision( TME) with pelvic autonomic nerve preservation( PANP) in the treatment of rectal cancer on the male urinary and sexual function and local recurrence rate. Methods: Seventy-one male patients with middle or low rectal cancer were randomly divided into treatment group( 36 cases) and control group( 35 cases) .The treatment group and control group were treated with PANP-TME and traditional radical resection of rectal cancer， respectively.The incidences of male urinary disfunction， sexual dysfunction and tumor local recurrence in two groups were compared.Results: The incidences of urinary dysfunction， erectile dysfunction，defective ejaculation and tumor local recurrence in treatment group and control group were 16.7% ＆54.3%， 30.6% ＆ 65.7%， 36.1%＆ 71.4% and 8.3% ＆ 11.4%， respectively.The differences of the incidence of urinary and sexual dysfunction in two groups had statistical significance( P 0.01) ， the difference of tumor local recurrence rate in two groups had no statistical significance ( P 0.05 ) . Conclusions: TME with PANP can effectively reduce the incidences of postoperative urinary dysfunction and sexual dysfunction，but it does not increase postoperative local recurence rate.
ObjectiveTo evaluate the effects of total mesorectal excision( TME) with pelvic autonomic nerve preservation( PANP) in the treatment of rectal cancer on the male urinary and sexual function and local recurrence rate. Methods: Seventy-one male patients with middle or low rectal cancer were randomly divided into treatment group( 36 cases) and control group( 35 cases) .The treatment group and control group were treated with PANP-TME and traditional radical resection of rectal cancer， respectively.The incidences of male urinary disfunction， sexual dysfunction and tumor local recurrence in two groups were compared.Results: The incidences of urinary dysfunction， erectile dysfunction，defective ejaculation and tumor local recurrence in treatment group and control group were 16.7% ＆54.3%， 30.6% ＆ 65.7%， 36.1%＆ 71.4% and 8.3% ＆ 11.4%， respectively.The differences of the incidence of urinary and sexual dysfunction in two groups had statistical significance( P 0.01) ， the difference of tumor local recurrence rate in two groups had no statistical significance ( P 0.05 ) . Conclusions: TME with PANP can effectively reduce the incidences of postoperative urinary dysfunction and sexual dysfunction，but it does not increase postoperative local recurence rate.
2013, 37(9): 1130-1132.
Abstract:
ObjectiveTo investigate the effects of posterior monosegmental fixation combined with single cage bone graft in thetreatment of lumbar spondylolisthesis. Methods: Forty-eight cases with lumbar spondylolisthesis were treated with posterior monosegmental fixation combined with single cage bone graft， the bone graft fusion time and postoperative excellent rate of all cases were observed.Results: Forty-six cases were followed up for 11 to 30 months.The bone graft fusion time was 4 to 9 months.Solid fusion in 43 cases，probable fusion in 2 cases and no fusion in 1 case were found， the infusion rate was 97.83%.The postoperative effects of 25cases， 19 cases and 2 cases were excellent， good and ordinary， respectively， the excellent and good rate was 95.65%. Conclusions: The posterior monosegmental fixation combined with single cage bone graft in the treatment of lumbar spondylolisthesis is good reset and fixation， and high fusion rate.
ObjectiveTo investigate the effects of posterior monosegmental fixation combined with single cage bone graft in thetreatment of lumbar spondylolisthesis. Methods: Forty-eight cases with lumbar spondylolisthesis were treated with posterior monosegmental fixation combined with single cage bone graft， the bone graft fusion time and postoperative excellent rate of all cases were observed.Results: Forty-six cases were followed up for 11 to 30 months.The bone graft fusion time was 4 to 9 months.Solid fusion in 43 cases，probable fusion in 2 cases and no fusion in 1 case were found， the infusion rate was 97.83%.The postoperative effects of 25cases， 19 cases and 2 cases were excellent， good and ordinary， respectively， the excellent and good rate was 95.65%. Conclusions: The posterior monosegmental fixation combined with single cage bone graft in the treatment of lumbar spondylolisthesis is good reset and fixation， and high fusion rate.
2013, 37(9): 1133-1135.
Abstract:
ObjectiveTo analyze the risk factor which progressing to cerebral infarction( CI) after transient ischemic attack( TIA) in a short term. Methods: Twenty-four cases of the total 92 TIA patients who progressing to CI were included into experimental group and the rest 68 patients were included into control group.Used single factor analysis， the influence factors of CI which progressed from TIA were analyzed by multi-factor logistic analysis.The progression to CI of the different ABCD2 scores in 30 days were observed.Results:There were significant differences between the two groups in hypertension，diabetes， coronary artery disease， symptoms duration time and intracranial artery stenosis ( P 0.05 to P 0.01) .The results of multi-factor analysis showed that intracranial artery stenosis，symptoms duration time which was longer than 60 minutes，diabetes，hypertension and coronary artery disease were all the risk factors of the progression( P 0.05 to P 0.01) .The scores of ABCD2 was highe， the possibility of progression to CI was increased( P 0.05) . Conclusions: ABCD2 scale not only includes the risk factors of diabetes and hypertension，also contains the assessment of symptom.ABCD2 scale is convenient to be used in clinic and the accuracy will be enhanced if combining with imaging examine.
ObjectiveTo analyze the risk factor which progressing to cerebral infarction( CI) after transient ischemic attack( TIA) in a short term. Methods: Twenty-four cases of the total 92 TIA patients who progressing to CI were included into experimental group and the rest 68 patients were included into control group.Used single factor analysis， the influence factors of CI which progressed from TIA were analyzed by multi-factor logistic analysis.The progression to CI of the different ABCD2 scores in 30 days were observed.Results:There were significant differences between the two groups in hypertension，diabetes， coronary artery disease， symptoms duration time and intracranial artery stenosis ( P 0.05 to P 0.01) .The results of multi-factor analysis showed that intracranial artery stenosis，symptoms duration time which was longer than 60 minutes，diabetes，hypertension and coronary artery disease were all the risk factors of the progression( P 0.05 to P 0.01) .The scores of ABCD2 was highe， the possibility of progression to CI was increased( P 0.05) . Conclusions: ABCD2 scale not only includes the risk factors of diabetes and hypertension，also contains the assessment of symptom.ABCD2 scale is convenient to be used in clinic and the accuracy will be enhanced if combining with imaging examine.
2013, 37(9): 1136-1137.
Abstract:
ObjectiveTo explore the significance of the bilirubin levels of neonates after 24 hours in predicting neonatal jaundice.Methods: The serum bilirubin levels of 118 neonates at 24，48 and 72 hours after birth were detected.Results: The serum bilirubin levels of neonates at 24， 48 and 72 hours after birth were( 94.5 25.6) ，( 176.5 42.1) and( 230.1 42.3) mol /L， respectively，the difference of which had statistical significance( P 0.01) .The incidence of pathologic jaundice increased with the increasing of serum bilirubin levels of neonates after 24 hours( P 0.01) . Conclusions: The levels of serum bilirubin of neonates after 24 hours can predict the incidence of neonatal jaundice.The proper diagnosis and treatment can reduce the incidence of pathologic jaundice and prevent bilirubin encephalopathy.
ObjectiveTo explore the significance of the bilirubin levels of neonates after 24 hours in predicting neonatal jaundice.Methods: The serum bilirubin levels of 118 neonates at 24，48 and 72 hours after birth were detected.Results: The serum bilirubin levels of neonates at 24， 48 and 72 hours after birth were( 94.5 25.6) ，( 176.5 42.1) and( 230.1 42.3) mol /L， respectively，the difference of which had statistical significance( P 0.01) .The incidence of pathologic jaundice increased with the increasing of serum bilirubin levels of neonates after 24 hours( P 0.01) . Conclusions: The levels of serum bilirubin of neonates after 24 hours can predict the incidence of neonatal jaundice.The proper diagnosis and treatment can reduce the incidence of pathologic jaundice and prevent bilirubin encephalopathy.
2013, 37(9): 1138-1139.
Abstract:
ObjectiveTo observe the clinical effects and safety of two kinds of azithromycin scheme in the treatment of mycoplasmapneumonia in children. Methods: Seventy-six cases treated with 7 － 4 － 3 solution of azithromycin and 80 cases treated with 5 － 4 － 5 solution of azithromycin were divided into observation group and control group by randomized controlled methods.The curative effects，the antifebrile time， cough relief time， the rale disappearing time and adverse reaction rate in two groups were compared.Results: The differences of curative effects and antifebrile time between two groups had no statistical significance( P 0.05) ， the differences of cough relief time，the rale disappearing time and adverse reaction rate between two groups had statistical significance ( P 0.05 ) . Conclusions: The 5 － 4 － 5 solution of azithromycin in treating mycoplasma pneumonia of children is good， safe and reliable，which is worth popularization and application in clinic
ObjectiveTo observe the clinical effects and safety of two kinds of azithromycin scheme in the treatment of mycoplasmapneumonia in children. Methods: Seventy-six cases treated with 7 － 4 － 3 solution of azithromycin and 80 cases treated with 5 － 4 － 5 solution of azithromycin were divided into observation group and control group by randomized controlled methods.The curative effects，the antifebrile time， cough relief time， the rale disappearing time and adverse reaction rate in two groups were compared.Results: The differences of curative effects and antifebrile time between two groups had no statistical significance( P 0.05) ， the differences of cough relief time，the rale disappearing time and adverse reaction rate between two groups had statistical significance ( P 0.05 ) . Conclusions: The 5 － 4 － 5 solution of azithromycin in treating mycoplasma pneumonia of children is good， safe and reliable，which is worth popularization and application in clinic
2013, 37(9): 1140-1142.
Abstract:
ObjectiveTo explore the effects of adrenaline combined with vasopressin in cardiopulmonary resuscitation. Methods: The data of 67 cases with respiratory and cardiac arrest were retrospectively.All cases were divided into the treatment group( 42 cases)which were treated with the first dose of 1 mg adrenaline， and 40 IU vasopressin added after 3 minutes.In the control group( 35 cases)which were treated with 1 mg adrenaline.The spontaneous recovery time of heart rate， the effective recovery cases of 1 hour， the successful recovery cases of 24 hours and the survival cases after discharge of two groups were observed.Results: The spontaneous recovery time of heart rate， the effective recovery cases of 1 hour， the successful recovery cases of 24 hours of the treatmet group were obviously better than that of the control group( P 0.05) .There was no significantly statistical difference between the survival cases after discharge of two groups( P 0.05) . Conclusions: The treatment with adrenaline combined with vasopressin in cardiopulmonary resuscitation can short the recovery time of spontaneous cardiac rhythm， improve the recovery efficiency of 1 hour and 24 hours，but there was not significant effects on the survival cases after discharge between two groups
ObjectiveTo explore the effects of adrenaline combined with vasopressin in cardiopulmonary resuscitation. Methods: The data of 67 cases with respiratory and cardiac arrest were retrospectively.All cases were divided into the treatment group( 42 cases)which were treated with the first dose of 1 mg adrenaline， and 40 IU vasopressin added after 3 minutes.In the control group( 35 cases)which were treated with 1 mg adrenaline.The spontaneous recovery time of heart rate， the effective recovery cases of 1 hour， the successful recovery cases of 24 hours and the survival cases after discharge of two groups were observed.Results: The spontaneous recovery time of heart rate， the effective recovery cases of 1 hour， the successful recovery cases of 24 hours of the treatmet group were obviously better than that of the control group( P 0.05) .There was no significantly statistical difference between the survival cases after discharge of two groups( P 0.05) . Conclusions: The treatment with adrenaline combined with vasopressin in cardiopulmonary resuscitation can short the recovery time of spontaneous cardiac rhythm， improve the recovery efficiency of 1 hour and 24 hours，but there was not significant effects on the survival cases after discharge between two groups
2013, 37(9): 1144-1146.
Abstract:
ObjectiveTo compare the effects of 10d sequential and standard triple therapy in the eradication of Helicobacter pylori ( Hp) . Methods: Ninty-two cases with chronic gastritis or peptic ulcer and positive Hp diagnosed by endoscopy were randomly divided into treatment group and control group.The control group were standard triple therapy( including 20 mg of esomeprazole，1 000 mg of amoxicillin and 500 mg of clarithromycin twice a day for 10 days.The treatment group were treated with sequential therapy( including 20 mg of esomeprazole，1 000 mg of amoxicillin for 5 days， followed by 20 mg of esomeprazole，500 mg of clarithromycin and 500 mg of tinidazole) for 5 days.Results: The eradication rates of Hp in treatment group and control group were 92.00% and 76.31% by following up， respectively， the difference of which was statistical significance( P 0.01) .The remission rate and incidence of adverse reactions between two groups were not statistical significance( P 0.05) . Conclusions: Sequential therapy can improve the eradication rate of Hp，which is economy， security and an alternative first-line treatment.
ObjectiveTo compare the effects of 10d sequential and standard triple therapy in the eradication of Helicobacter pylori ( Hp) . Methods: Ninty-two cases with chronic gastritis or peptic ulcer and positive Hp diagnosed by endoscopy were randomly divided into treatment group and control group.The control group were standard triple therapy( including 20 mg of esomeprazole，1 000 mg of amoxicillin and 500 mg of clarithromycin twice a day for 10 days.The treatment group were treated with sequential therapy( including 20 mg of esomeprazole，1 000 mg of amoxicillin for 5 days， followed by 20 mg of esomeprazole，500 mg of clarithromycin and 500 mg of tinidazole) for 5 days.Results: The eradication rates of Hp in treatment group and control group were 92.00% and 76.31% by following up， respectively， the difference of which was statistical significance( P 0.01) .The remission rate and incidence of adverse reactions between two groups were not statistical significance( P 0.05) . Conclusions: Sequential therapy can improve the eradication rate of Hp，which is economy， security and an alternative first-line treatment.
2013, 37(9): 1182-1183.
Abstract:
ObjectiveTo explore the clinical value of the changes of C reaction protein ( CＲP) and ceruloplasmin ( Cp) in late pregnancy and delivery. Methods: The serum CＲP and Cp of 98 normal delivery women，99 cesarean section women，38 antenatal examination women and 25 healthy women( control group) were detected. Ｒesults: The serum Cp level in the normal delivery group，cesarean section group and antenatal examination group was markedly increased compared with that of the control( P 0.01) ; the serum CＲP level of the cesarean section group was higher than that of the control group and the normal delivery group( P 0.01) ; and the CＲP and Cp levels in other groups had no statistical difference( P 0.05) . Conclusions: CＲP and Cp can be used as predictors in late pregnancy and delivery.
ObjectiveTo explore the clinical value of the changes of C reaction protein ( CＲP) and ceruloplasmin ( Cp) in late pregnancy and delivery. Methods: The serum CＲP and Cp of 98 normal delivery women，99 cesarean section women，38 antenatal examination women and 25 healthy women( control group) were detected. Ｒesults: The serum Cp level in the normal delivery group，cesarean section group and antenatal examination group was markedly increased compared with that of the control( P 0.01) ; the serum CＲP level of the cesarean section group was higher than that of the control group and the normal delivery group( P 0.01) ; and the CＲP and Cp levels in other groups had no statistical difference( P 0.05) . Conclusions: CＲP and Cp can be used as predictors in late pregnancy and delivery.
2013, 37(9): 1187-1189.
Abstract:
ObjectiveTo summary CT manifestation of secondary pulmonary mycotic infection in leukemia， to improve diagnosis and understanding of the disease. Methods: Analyzed CT findings and clinical data of 25 cases of IPA in leukemia，record image characteristic of the type，distribution，morphology， size，number.Results: In 25 cases， 12 cases of consolidative， single patch in 3 cases，multiple patchy in 9 cases， there are real shadows in 5 cases，bronchial gas phase in 6 cases，5 cases of concurrent single /multiple nodules with hemorrhagic pulmonary infarction; change sign in 15 cases， for pointing toward the hilum，wedge-shaped lesions in the bottom of the pleura，bronchi and gas phase in 9 cases， at the same time to see the small cavity in 3 cases.Mass type: single or multiple nodules or masses in 7 cases，4 cases with patchy lesions， found around the halo sign in 5 cases; see air crescent sign in 2 cases.Six cases of mixed type，also visible above two.Others: Eight cases of adjacent pleural thickening and adhesion，2 cases with calcification. Conclusions: CT findings of IPA in leukemia are various，nodule and halo signand /or wedge consolidation and air bronchogram are the specific manifestation on CT images，which are contributed to diagnose early and reduce misdiagnosis.
ObjectiveTo summary CT manifestation of secondary pulmonary mycotic infection in leukemia， to improve diagnosis and understanding of the disease. Methods: Analyzed CT findings and clinical data of 25 cases of IPA in leukemia，record image characteristic of the type，distribution，morphology， size，number.Results: In 25 cases， 12 cases of consolidative， single patch in 3 cases，multiple patchy in 9 cases， there are real shadows in 5 cases，bronchial gas phase in 6 cases，5 cases of concurrent single /multiple nodules with hemorrhagic pulmonary infarction; change sign in 15 cases， for pointing toward the hilum，wedge-shaped lesions in the bottom of the pleura，bronchi and gas phase in 9 cases， at the same time to see the small cavity in 3 cases.Mass type: single or multiple nodules or masses in 7 cases，4 cases with patchy lesions， found around the halo sign in 5 cases; see air crescent sign in 2 cases.Six cases of mixed type，also visible above two.Others: Eight cases of adjacent pleural thickening and adhesion，2 cases with calcification. Conclusions: CT findings of IPA in leukemia are various，nodule and halo signand /or wedge consolidation and air bronchogram are the specific manifestation on CT images，which are contributed to diagnose early and reduce misdiagnosis.
2013, 37(9): 1194-1196.
Abstract:
ObjectiveTo explore the effects of whole course nursing intervention in the prevention of adverse reactions caused by fundus fluorescein angiography( FFA) . Methods: Two hundred and sixty-six patients undergone FFA were divided into the intervention group( 141 cases) and control group( 125 cases) .The control group were nursed with conventional nursing.The intervention group were nursed with whole course nursing intervention including the psychological nursig of adverse reactions of gastrointestinal tract，nervous system and allergy，slide education and seeing on the spot based on the conventional nursing.The adverse reactions and patient satisfaction of nursing intervention of two groups were observed. Results: The incidence of gastrointestinal tract and nervous system reactions of the intervention group were lower than those in the control group( P 0.01 and P 0.05) .The patient satisfaction of the intervention group( 97.2%) was significantly higher than that of the control group( 84.8%) ( P 0.01) . Conclusions: During the course of FFA examination and treatment， the psychological nursing，multimedia education and seeing on the spot can greatly reduce the tension and fear of patients，prevent and reduce the occurrence of adverse reactions and improve patient satisfaction，which can obstain the most best examination effects.
ObjectiveTo explore the effects of whole course nursing intervention in the prevention of adverse reactions caused by fundus fluorescein angiography( FFA) . Methods: Two hundred and sixty-six patients undergone FFA were divided into the intervention group( 141 cases) and control group( 125 cases) .The control group were nursed with conventional nursing.The intervention group were nursed with whole course nursing intervention including the psychological nursig of adverse reactions of gastrointestinal tract，nervous system and allergy，slide education and seeing on the spot based on the conventional nursing.The adverse reactions and patient satisfaction of nursing intervention of two groups were observed. Results: The incidence of gastrointestinal tract and nervous system reactions of the intervention group were lower than those in the control group( P 0.01 and P 0.05) .The patient satisfaction of the intervention group( 97.2%) was significantly higher than that of the control group( 84.8%) ( P 0.01) . Conclusions: During the course of FFA examination and treatment， the psychological nursing，multimedia education and seeing on the spot can greatly reduce the tension and fear of patients，prevent and reduce the occurrence of adverse reactions and improve patient satisfaction，which can obstain the most best examination effects.
2013, 37(9): 1197-1199.
Abstract:
ObjectiveTo investigate the influence of systematic nursing intervention on treatment effect and quality of life in elderly patients with hypertension. Methods: One hundred and twenty elderly patients with primary hypertension were randomly divided into observation group and control group( 60 cases each group) .The control group were treated with internal medicine combined with routine nursing measures according to the patients' condition.The observation group were treated with systematic nursing intervention on the basis of the control group.All patients were followed up for 3 months.The blood pressure，medication compliance，knowledge of disease awareness，occurrence rate of complication and quality of life in two groups were compared. Results: The blood pressure，medication compliance and knowledge of disease awareness in observation group were better than those in control group( P 0.01) .The occurrence rate of complication in observation group was significantly less than that in control group ( P 0.01) .The healthy feeling，somatic sensation， sleep condition， life satisfaction and cognitive function and quality of life in observation group were significantly higher than those in the control group( P 0.01) . Conclusions: The systematic nursing intervention can significantly improve the blood pressure control and quality of life of elderly patients with hypertension.
ObjectiveTo investigate the influence of systematic nursing intervention on treatment effect and quality of life in elderly patients with hypertension. Methods: One hundred and twenty elderly patients with primary hypertension were randomly divided into observation group and control group( 60 cases each group) .The control group were treated with internal medicine combined with routine nursing measures according to the patients' condition.The observation group were treated with systematic nursing intervention on the basis of the control group.All patients were followed up for 3 months.The blood pressure，medication compliance，knowledge of disease awareness，occurrence rate of complication and quality of life in two groups were compared. Results: The blood pressure，medication compliance and knowledge of disease awareness in observation group were better than those in control group( P 0.01) .The occurrence rate of complication in observation group was significantly less than that in control group ( P 0.01) .The healthy feeling，somatic sensation， sleep condition， life satisfaction and cognitive function and quality of life in observation group were significantly higher than those in the control group( P 0.01) . Conclusions: The systematic nursing intervention can significantly improve the blood pressure control and quality of life of elderly patients with hypertension.
2013, 37(9): 1200-1202.
Abstract:
ObjectiveTo explore the psychological experience of the patients with hip replacement. Methods: Seven patients with hip replacement were investigated by semi-structured interview using phenomenology method in qualitative research， the interview data were analysed.Results: Five key themes of the psychological experience in patients included the panic caused by disease，effects of family members， the change of social life and work， self-correction and the expectations of rehabilitation period. Conclusions: The rehabilitation nursing of patients with hip replacement should include physiological，psychological and social aspects，which can promote the comprehensive rehabilitation of patients.
ObjectiveTo explore the psychological experience of the patients with hip replacement. Methods: Seven patients with hip replacement were investigated by semi-structured interview using phenomenology method in qualitative research， the interview data were analysed.Results: Five key themes of the psychological experience in patients included the panic caused by disease，effects of family members， the change of social life and work， self-correction and the expectations of rehabilitation period. Conclusions: The rehabilitation nursing of patients with hip replacement should include physiological，psychological and social aspects，which can promote the comprehensive rehabilitation of patients.
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