Author Login
Experts Review
Academic Editor
Editor-in-chief
2014 Vol. 39, No. 9
Display Method:
2014, 39(9): 1153-1155.
Abstract:
Objective: To observe the bone mineral density and the expression of blood serum osteoprotegerin(OPG)/receptor activator of nuclear factor-κB ligand(RANKL) protein in adjuvant arthritis rats.Methods: Thirty SD rats were randomly divided into normal control group,model 1 group and model 2 group.Except the normal control group,other rats were made of adjuvant arthritis model.At the 21st day,the bone mineral density of the whole right side of the tibia and about 1 cm from the distal tibia called interest region in model 1 group were detected with dualenergy X-ray absorptoimetry.At the 28th day,the bone mineral density of the whole right side of the tibia and about 1 cm from the distal tibia called interest region in model 2 group and normal group were detected.At the same time,the expression of blood serum OPG/RANKL of adjuvant arthritis rats was inspected by enzyme-linked immuno sorbent assay.Results: The bone mineral density of interest region of model 1 group were lower than that of normal group(P<0.01).The interest region of model 2 group significantly reduced compared with the normal and model 1 groups(P<0.01).The overall right tibia bone mineral density had no significant difference(P>0.05).The expression of blood serum OPG,RANKL and the OPG/RANKL ratio in model 1 and model 2 group were significantly different with the normal group(P<0.01).At the same time,the expression of blood serum OPG,RANKL and the OPG/RANKL ratio in model 2 were significantly different with model 1 group(P<0.01).Conclusions: Adjuvant arthritis rats lost distal tibial bone earlier than the whole tibial.The blood serum OPG expression is decreased,the blood serum RANKL is increased,and the ratio of OPG/RANKL is decreased after modeling 21 days and 28 days.
Objective: To observe the bone mineral density and the expression of blood serum osteoprotegerin(OPG)/receptor activator of nuclear factor-κB ligand(RANKL) protein in adjuvant arthritis rats.Methods: Thirty SD rats were randomly divided into normal control group,model 1 group and model 2 group.Except the normal control group,other rats were made of adjuvant arthritis model.At the 21st day,the bone mineral density of the whole right side of the tibia and about 1 cm from the distal tibia called interest region in model 1 group were detected with dualenergy X-ray absorptoimetry.At the 28th day,the bone mineral density of the whole right side of the tibia and about 1 cm from the distal tibia called interest region in model 2 group and normal group were detected.At the same time,the expression of blood serum OPG/RANKL of adjuvant arthritis rats was inspected by enzyme-linked immuno sorbent assay.Results: The bone mineral density of interest region of model 1 group were lower than that of normal group(P<0.01).The interest region of model 2 group significantly reduced compared with the normal and model 1 groups(P<0.01).The overall right tibia bone mineral density had no significant difference(P>0.05).The expression of blood serum OPG,RANKL and the OPG/RANKL ratio in model 1 and model 2 group were significantly different with the normal group(P<0.01).At the same time,the expression of blood serum OPG,RANKL and the OPG/RANKL ratio in model 2 were significantly different with model 1 group(P<0.01).Conclusions: Adjuvant arthritis rats lost distal tibial bone earlier than the whole tibial.The blood serum OPG expression is decreased,the blood serum RANKL is increased,and the ratio of OPG/RANKL is decreased after modeling 21 days and 28 days.
2014, 39(9): 1156-1158.
Abstract:
Objective: To explore the correlation of SGSM3 rs56228771 polymorphisms and susceptibility of colorectal cancer in Han people.Methods: The distribution frequencies of SGSM3 rs56228771 in 339 Han patients with colorectal cancer(colorectal neoplasm group) and 319 healthy people were detected using non-denaturing PAGE.The odds ratio(OR) and 95% confidence intervals(CI) of age,sex,smoking and drinking status after adjustment were calculated using unconditional logistic regression analysis.Results: The frequencies of SGSM3 I/I,I/D and D/D genotypes in colorectal cancer group and control group were 2.36%,24.78% and 72.86%,and 4.08%,33.86% and 62.07%,respectively,the differences of whose were statistically significant(P<0.05).The risk of colorectal cancer in cases with SGSM3 I/I genotype was lower than that in cases with D/D genotype(OR=0.62,95%CI 0.20 to 1.21,P<0.05).The risk of colorectal cancer in cases with SGSM3 I gene was lower than that in cases with D gene(OR=0.49,95%CI 0.49 to 0.87,P<0.01).Conclusions: The SGSM3 rs56228771 polymorphism is directly related to the susceptibility of colorectal cancer in Han people.
Objective: To explore the correlation of SGSM3 rs56228771 polymorphisms and susceptibility of colorectal cancer in Han people.Methods: The distribution frequencies of SGSM3 rs56228771 in 339 Han patients with colorectal cancer(colorectal neoplasm group) and 319 healthy people were detected using non-denaturing PAGE.The odds ratio(OR) and 95% confidence intervals(CI) of age,sex,smoking and drinking status after adjustment were calculated using unconditional logistic regression analysis.Results: The frequencies of SGSM3 I/I,I/D and D/D genotypes in colorectal cancer group and control group were 2.36%,24.78% and 72.86%,and 4.08%,33.86% and 62.07%,respectively,the differences of whose were statistically significant(P<0.05).The risk of colorectal cancer in cases with SGSM3 I/I genotype was lower than that in cases with D/D genotype(OR=0.62,95%CI 0.20 to 1.21,P<0.05).The risk of colorectal cancer in cases with SGSM3 I gene was lower than that in cases with D gene(OR=0.49,95%CI 0.49 to 0.87,P<0.01).Conclusions: The SGSM3 rs56228771 polymorphism is directly related to the susceptibility of colorectal cancer in Han people.
2014, 39(9): 1159-1162,1167.
Abstract:
Objective: To study the effects of losartan on lung injury during cardiopulmonary bypass(CPB) in dogs,and its mechanism.Methods: Twelve adult healthy mongrel dogs,weighing(14.25±1.60) kg,were randomly divided into the control group(group C,n=6) and losartan group(group L,n=6).The CPB model of dog was established.The group L and C were intravenously injected with 1 mg/kg of losartan and 0.9% sodium chloride at 30 min before CPB,respectively.The plasma levels of angiotensinⅡ(AngⅡ) and malondialdehyde(MDA) in two groups were measured before injecting(T1),at 45 min after aortic cross-clamping(T2),and at 30 min(T3) and 60 min(T4) after aortic unclamping.The oxygenation index(OI) and respiratory index(RI) were calculated at T1 and T4,and their lung tissue structures were observed under optical microscope.Results: Compared with T1,the plasma levels of AngⅡ and MDA in two groups at T2-4 increased significantly(P<0.01),and the OI and RI at T4 in two groups decreased and increased,respectively(P<0.05-P<0.01).The differences of the plasma levels of AngⅡ in all time points between Group L and C were not statistical significance(P>0.05).At T4,the level of MDA in group L was significantly lower than that in group C(P<0.01).The differences of the OI and RI at T4 between two groups were not statistical significance(P>0.05),and the lung injury in group L was lighter than that in group C at T4.Conclusions: Losartan can block the role of AngⅡ,and restrain oxidative stress,which can prevent the lung injury caused by CPB.
Objective: To study the effects of losartan on lung injury during cardiopulmonary bypass(CPB) in dogs,and its mechanism.Methods: Twelve adult healthy mongrel dogs,weighing(14.25±1.60) kg,were randomly divided into the control group(group C,n=6) and losartan group(group L,n=6).The CPB model of dog was established.The group L and C were intravenously injected with 1 mg/kg of losartan and 0.9% sodium chloride at 30 min before CPB,respectively.The plasma levels of angiotensinⅡ(AngⅡ) and malondialdehyde(MDA) in two groups were measured before injecting(T1),at 45 min after aortic cross-clamping(T2),and at 30 min(T3) and 60 min(T4) after aortic unclamping.The oxygenation index(OI) and respiratory index(RI) were calculated at T1 and T4,and their lung tissue structures were observed under optical microscope.Results: Compared with T1,the plasma levels of AngⅡ and MDA in two groups at T2-4 increased significantly(P<0.01),and the OI and RI at T4 in two groups decreased and increased,respectively(P<0.05-P<0.01).The differences of the plasma levels of AngⅡ in all time points between Group L and C were not statistical significance(P>0.05).At T4,the level of MDA in group L was significantly lower than that in group C(P<0.01).The differences of the OI and RI at T4 between two groups were not statistical significance(P>0.05),and the lung injury in group L was lighter than that in group C at T4.Conclusions: Losartan can block the role of AngⅡ,and restrain oxidative stress,which can prevent the lung injury caused by CPB.
2014, 39(9): 1163-1167.
Abstract:
Objective: To explore the expressions of hypoxia-inducible factor-1α(HIF-1α) and glucose transporter protein-1(GLUT-1) in human lumbar disc degeneration and its significance.Methods: The nucleus pulposus tissues from the normal intervertebral disc of younger with lumbar burst fracture and degenerative intervertebral disc of patients were divided into the control group and experiment group,respectively,and the experiment group were subdivided into two groups according to their preoperative MRI images.The expressions of HIF-1α and GLUT-1 in 3 groups were analyzed by immunohistochemistry and RT-PCR.Results: Immunohistochemistry showed that the HIF-1α and GLUT-1 expressions were weak positive in control group,positive in moderate degeneration group and strongly positive in severe degeneration group.The expressions of HIF-1α and GLUT-1 strengthened with the degeneration degree of lumbar intervertebral disc aggravating(P<0.01).RT-PCR showed that the expressions of HIF-1α and GLUT-1 genes were found in human disc tissue,and the differences of the expressions of HIF-1α and GLUT-1 between 3 groups were statistically significant(P<0.01).Conclusions: HIF-1α and GLUT-1 are likely to participate in the degeneration of human lumbar disc,and their expressions show the same increasing trend.The detections of HIF-1α and GLUT-1 in human lumbar disc tissue can predict the degeneration of human lumbar disc,which can provide a new knowledge in the prevention and treatment of lumbar disc degeneration.
Objective: To explore the expressions of hypoxia-inducible factor-1α(HIF-1α) and glucose transporter protein-1(GLUT-1) in human lumbar disc degeneration and its significance.Methods: The nucleus pulposus tissues from the normal intervertebral disc of younger with lumbar burst fracture and degenerative intervertebral disc of patients were divided into the control group and experiment group,respectively,and the experiment group were subdivided into two groups according to their preoperative MRI images.The expressions of HIF-1α and GLUT-1 in 3 groups were analyzed by immunohistochemistry and RT-PCR.Results: Immunohistochemistry showed that the HIF-1α and GLUT-1 expressions were weak positive in control group,positive in moderate degeneration group and strongly positive in severe degeneration group.The expressions of HIF-1α and GLUT-1 strengthened with the degeneration degree of lumbar intervertebral disc aggravating(P<0.01).RT-PCR showed that the expressions of HIF-1α and GLUT-1 genes were found in human disc tissue,and the differences of the expressions of HIF-1α and GLUT-1 between 3 groups were statistically significant(P<0.01).Conclusions: HIF-1α and GLUT-1 are likely to participate in the degeneration of human lumbar disc,and their expressions show the same increasing trend.The detections of HIF-1α and GLUT-1 in human lumbar disc tissue can predict the degeneration of human lumbar disc,which can provide a new knowledge in the prevention and treatment of lumbar disc degeneration.
2014, 39(9): 1168-1169,1172.
Abstract:
Objective: To observe the effects and adverse reactions of the sequential therapy of conventional chemotherapy combined with gefitinib in the treatment of advanced lung adenocarcinoma in elderly patients.Methods: Fifteen elderly patients with advanced lung adenocarcinoma were treated with conventional chemotherapy one cycle every 3 weeks for less than six cycles,the gefitinib was used after chemotherapy or disease progression during chemotherapy until the patients could not tolerate.The short-term effects and adverse reactions of the patients were observed.Results: Among 15 patients,partial remission in 5 cases(33.3%),stable disease in 7 cases(46.7%) and disease progression in 3 cases(20.0%) were found,the effective rate,disease control rate and 1-year survival rate of which were 33.3%,80.0%,and 33.3%,respectively.The bone marrow suppression,gastrointestinal reaction and skin rash were the major adverse reactions.Conclusions: The sequential therapy of conventional chemotherapy combined with gefitinib in the treatment of advanced lung adenocarcinoma in elderly patients is good and safe.
Objective: To observe the effects and adverse reactions of the sequential therapy of conventional chemotherapy combined with gefitinib in the treatment of advanced lung adenocarcinoma in elderly patients.Methods: Fifteen elderly patients with advanced lung adenocarcinoma were treated with conventional chemotherapy one cycle every 3 weeks for less than six cycles,the gefitinib was used after chemotherapy or disease progression during chemotherapy until the patients could not tolerate.The short-term effects and adverse reactions of the patients were observed.Results: Among 15 patients,partial remission in 5 cases(33.3%),stable disease in 7 cases(46.7%) and disease progression in 3 cases(20.0%) were found,the effective rate,disease control rate and 1-year survival rate of which were 33.3%,80.0%,and 33.3%,respectively.The bone marrow suppression,gastrointestinal reaction and skin rash were the major adverse reactions.Conclusions: The sequential therapy of conventional chemotherapy combined with gefitinib in the treatment of advanced lung adenocarcinoma in elderly patients is good and safe.
2014, 39(9): 1170-1172.
Abstract:
Objective: To evaluate the value of dissecting level Ⅲ lymph nodes in modified radical mastectomy of breast cancer patient with positive axillary lymph nodes.Methods: The breast carcinoma patients with positive axillary lymph nodes were screened by physical examination or ultrasound imaging.The patients were treated with the modified radical mastectomy or modified radical mastectomy combined with level Ⅲ lymph nodes dissection.The clinical effects of two kinds of operations were compared.Results: Forty-two patients were treated with level Ⅲ lymph nodes dissection.Among 42 patients,the positive axillary lymph nodes in 41 cases(accompanied by postive level Ⅲ lymph nodes in 13 cases) were found.The rates of 3-year distant metastasis and supraclavicular lymph node metastasis were 9.5% and 2.4%,respectively.Seventeen patients were treated with the modified radical mastectomy,the rates of 3-year distant metastasis and supraclavicular lymph node metastasis were 35.3% and 23.5%,respectively.The differences of the rates of 3-year distant metastasis and supraclavicular lymph node metastasis between two kinds of operations were statistically significant(P<0.05).The overall survival rates of the patients treated with the modified radical mastectomy and modified radical mastectomy combined with level Ⅲ lymph nodes dissection were 92.9% and 88.2%,respectively,the difference of which was not statistically significant(P>0.05).Conclusions: Dissecting level Ⅲ lymph nodes in the treatment of the patients with positive axillary lymph nodes can thoroughly clean the axillary lymph nodes,and improve the postoperative treatment and prognosis.
Objective: To evaluate the value of dissecting level Ⅲ lymph nodes in modified radical mastectomy of breast cancer patient with positive axillary lymph nodes.Methods: The breast carcinoma patients with positive axillary lymph nodes were screened by physical examination or ultrasound imaging.The patients were treated with the modified radical mastectomy or modified radical mastectomy combined with level Ⅲ lymph nodes dissection.The clinical effects of two kinds of operations were compared.Results: Forty-two patients were treated with level Ⅲ lymph nodes dissection.Among 42 patients,the positive axillary lymph nodes in 41 cases(accompanied by postive level Ⅲ lymph nodes in 13 cases) were found.The rates of 3-year distant metastasis and supraclavicular lymph node metastasis were 9.5% and 2.4%,respectively.Seventeen patients were treated with the modified radical mastectomy,the rates of 3-year distant metastasis and supraclavicular lymph node metastasis were 35.3% and 23.5%,respectively.The differences of the rates of 3-year distant metastasis and supraclavicular lymph node metastasis between two kinds of operations were statistically significant(P<0.05).The overall survival rates of the patients treated with the modified radical mastectomy and modified radical mastectomy combined with level Ⅲ lymph nodes dissection were 92.9% and 88.2%,respectively,the difference of which was not statistically significant(P>0.05).Conclusions: Dissecting level Ⅲ lymph nodes in the treatment of the patients with positive axillary lymph nodes can thoroughly clean the axillary lymph nodes,and improve the postoperative treatment and prognosis.
2014, 39(9): 1173-1176.
Abstract:
Objective: To investigate the clinicopathological characteristics of primary ovarian strumal carcinoid(POSC).Methods: The clinicopathological characteristics of POSC in 4 cases were analyzed by light microscopy,immunohistochemistry and special stains.Results: The patients' clinical manifestations were lower abdominal pain,and no constipation and carcinoid syndrome.Ovarian cystic masses torsion was the initia symptom in 2 cases.The goiter and carcinoid tissue were transition,part cancer cells arranged in island or beam.The borderline mucinous cystadenoma in 1 case and mature teraloma in 3 cases were found.The neural cell adhesion molecule of immune phenotype cancer cells,synaptophysin,chromogranin and neuron specific enolase were positive.Conclusions: POSC is a rare germ cell tumor,which should be differentiated from granulosa cell tumor and Sertoli-Leydig cell tumor.HE and immunohistochemical stain will contribute to the diagnosis.
Objective: To investigate the clinicopathological characteristics of primary ovarian strumal carcinoid(POSC).Methods: The clinicopathological characteristics of POSC in 4 cases were analyzed by light microscopy,immunohistochemistry and special stains.Results: The patients' clinical manifestations were lower abdominal pain,and no constipation and carcinoid syndrome.Ovarian cystic masses torsion was the initia symptom in 2 cases.The goiter and carcinoid tissue were transition,part cancer cells arranged in island or beam.The borderline mucinous cystadenoma in 1 case and mature teraloma in 3 cases were found.The neural cell adhesion molecule of immune phenotype cancer cells,synaptophysin,chromogranin and neuron specific enolase were positive.Conclusions: POSC is a rare germ cell tumor,which should be differentiated from granulosa cell tumor and Sertoli-Leydig cell tumor.HE and immunohistochemical stain will contribute to the diagnosis.
2014, 39(9): 1176-1179.
Abstract:
Objective: To observe the effects of sufentanil combined with dexmedetomidine on postoperative analgesia in cervical cancer patients with radical hysterectomy.Methods: Fifty-six ASAⅠor Ⅱcervical cancer patients scheduled by radical hysterectomy were randomly divided into the observation group and control group(28 cases each group).At postoperative analgesia,the control group were treated with sufentanil for 1.0 μg·kg-1·d-1,the observation group were treated with sufentanil for 1.0 μg·kg-1·d-1 combined with dexmedetomidine for 1.0 μg·kg-1·d-1,the postoperative analgesia continuous perfusion amount for 2 ml/h,single bolus for 2 ml,lockout time for 15 min and total volume for 100 ml were implemented in two groups.The degree of pain and sedation grade in two groups were evaluated using visual analog scale(VAS) after operation(T1) and at 2(T2),8(T3),24(T4) and 48 hours(T5) after operation.The incidences of bladder discomfort,nausea and vomiting,and satisfaction of patients in two groups were recorded after operation.Results: The postoperative VAS scores in two groups in all time points were less than 4.The pain scores of the observation group at T2 to T5 were significantly lower than that of the control group(P<0.01).The Ramesay grades of the observation group at T2 to T5 were significantly lower than that of the control group(P<0.01).The incidences of bladder discomfort,nausea and vomiting in observation group were lower than those in control group(P<0.05),the satisfaction of patient in observation group were higher than that in control group(P<0.05).Conclusions: The postoperative analgesia effects of sufentanil combined with dexmedetomidine on radical hysterectomy are better than that of sufentanil,which is lower adverse reaction and more comfortable.
Objective: To observe the effects of sufentanil combined with dexmedetomidine on postoperative analgesia in cervical cancer patients with radical hysterectomy.Methods: Fifty-six ASAⅠor Ⅱcervical cancer patients scheduled by radical hysterectomy were randomly divided into the observation group and control group(28 cases each group).At postoperative analgesia,the control group were treated with sufentanil for 1.0 μg·kg-1·d-1,the observation group were treated with sufentanil for 1.0 μg·kg-1·d-1 combined with dexmedetomidine for 1.0 μg·kg-1·d-1,the postoperative analgesia continuous perfusion amount for 2 ml/h,single bolus for 2 ml,lockout time for 15 min and total volume for 100 ml were implemented in two groups.The degree of pain and sedation grade in two groups were evaluated using visual analog scale(VAS) after operation(T1) and at 2(T2),8(T3),24(T4) and 48 hours(T5) after operation.The incidences of bladder discomfort,nausea and vomiting,and satisfaction of patients in two groups were recorded after operation.Results: The postoperative VAS scores in two groups in all time points were less than 4.The pain scores of the observation group at T2 to T5 were significantly lower than that of the control group(P<0.01).The Ramesay grades of the observation group at T2 to T5 were significantly lower than that of the control group(P<0.01).The incidences of bladder discomfort,nausea and vomiting in observation group were lower than those in control group(P<0.05),the satisfaction of patient in observation group were higher than that in control group(P<0.05).Conclusions: The postoperative analgesia effects of sufentanil combined with dexmedetomidine on radical hysterectomy are better than that of sufentanil,which is lower adverse reaction and more comfortable.
2014, 39(9): 1180-1181,1184.
Abstract:
Objective: To compare the efficacy of totally extraperitoneal prosthesis(TEP) and open tension-free hernioplasty in inguinal hernia repair.Methods: One hundred and four patients treated with inguinal hernia repair were divided into the TEP group(46 cases) and open tension-free hernioplasty group(58 cases) according to their operation methods.The perioperative clinical parameters and recurrence rate between two groups were compared.Results: The therapeutic effects of two groups were better.The differences of the time of operation,postoperative pain,hospital stay and hospitalization expense between two groups were statistically significant(P<0.05).The differences of the blood loss and postoperative complications between two groups were not statistically significant(P>0.05).There was not recurrence in two groups after following up for 1 year.Conclusions: Both TEP and open tension-free hernioplasty in treating inguinal hernia are effective,the treatment should be selected according to patient condition.
Objective: To compare the efficacy of totally extraperitoneal prosthesis(TEP) and open tension-free hernioplasty in inguinal hernia repair.Methods: One hundred and four patients treated with inguinal hernia repair were divided into the TEP group(46 cases) and open tension-free hernioplasty group(58 cases) according to their operation methods.The perioperative clinical parameters and recurrence rate between two groups were compared.Results: The therapeutic effects of two groups were better.The differences of the time of operation,postoperative pain,hospital stay and hospitalization expense between two groups were statistically significant(P<0.05).The differences of the blood loss and postoperative complications between two groups were not statistically significant(P>0.05).There was not recurrence in two groups after following up for 1 year.Conclusions: Both TEP and open tension-free hernioplasty in treating inguinal hernia are effective,the treatment should be selected according to patient condition.
2014, 39(9): 1182-1184.
Abstract:
Objective: To explore the clinical effects of complete video-assisted-thoracoscopic lobectomy and thoracoscopic lobectomy in the treatment of non-small cell lung cancer at early stage.Methods: The clinical data of 60 patients with non small cell lung cancer treated with lobectomy were analyzed.The patients treated with thoracoscopic lobectomy(30 cases) and complete video-assisted-thoracoscopic lobectomy(30 cases) were divided into control group(OT group) and observation group(VATS group),respectively.The patient selection,operation time,volume of intraoperative bleeding loss,number of lymph node dissection,volume of postoperative drainage,postoperative hospital stay,incidence of postoperative complication and total cost of hospitalization between two groups were compared.Results: The volume of intraoperative bleeding loss and postoperative hospital stay in VAST group were significantly less than those in OT group(P<0.05),but its total cost of hospitalization was significantly higher than that in OT group.The differences of the number of lymph node dissection,volume of postoperative drainage,operation time and incidence of postoperative complication between two groups were not statistically significant(P>0.05).Conclusions: The complete video-assisted-thoracoscopic surgery lobectomy in the treatment of non-small cell lung cancer at early stage is safe and effective,which is worthy of clinical use.
Objective: To explore the clinical effects of complete video-assisted-thoracoscopic lobectomy and thoracoscopic lobectomy in the treatment of non-small cell lung cancer at early stage.Methods: The clinical data of 60 patients with non small cell lung cancer treated with lobectomy were analyzed.The patients treated with thoracoscopic lobectomy(30 cases) and complete video-assisted-thoracoscopic lobectomy(30 cases) were divided into control group(OT group) and observation group(VATS group),respectively.The patient selection,operation time,volume of intraoperative bleeding loss,number of lymph node dissection,volume of postoperative drainage,postoperative hospital stay,incidence of postoperative complication and total cost of hospitalization between two groups were compared.Results: The volume of intraoperative bleeding loss and postoperative hospital stay in VAST group were significantly less than those in OT group(P<0.05),but its total cost of hospitalization was significantly higher than that in OT group.The differences of the number of lymph node dissection,volume of postoperative drainage,operation time and incidence of postoperative complication between two groups were not statistically significant(P>0.05).Conclusions: The complete video-assisted-thoracoscopic surgery lobectomy in the treatment of non-small cell lung cancer at early stage is safe and effective,which is worthy of clinical use.
2014, 39(9): 1185-1186.
Abstract:
Objective: To discuss the efficacy and safety of hepatitis B immunoglobulin(HBIG) in blocking the hepatitis B virus(HBV) transmission in mother-to-infant.Methods: One hundred and ten HBV puerperal carriers were divided into the observation group and control group on voluntary basis(55 cases each group).The observation group were injected with HBIG at 28 gestational weeks,and the control group did not be injected.The detection rates of hepatitis B surface antigen(HBsAg) in newborns and hepatitis B surface antibody(HBsAb) in newborns after 6-month treatment between two groups were compared.Results: The detection rates of newborns HBsAg in observation group and control group were 9.09% and 34.55%,respectively,the difference of which was statistical significance(P<0.01).The detection rate of HBsAb in newborns after 6-month treatment(64.55%) was significantly better than that in 1-month newborns(22.72%)(P<0.01),and there were not significant adverse reactions in pregnant woman and newborn.Conclusions: HBIG in blocking the HBV transmission in mother-to-infant is effective and safe,which can be applied in clinic.
Objective: To discuss the efficacy and safety of hepatitis B immunoglobulin(HBIG) in blocking the hepatitis B virus(HBV) transmission in mother-to-infant.Methods: One hundred and ten HBV puerperal carriers were divided into the observation group and control group on voluntary basis(55 cases each group).The observation group were injected with HBIG at 28 gestational weeks,and the control group did not be injected.The detection rates of hepatitis B surface antigen(HBsAg) in newborns and hepatitis B surface antibody(HBsAb) in newborns after 6-month treatment between two groups were compared.Results: The detection rates of newborns HBsAg in observation group and control group were 9.09% and 34.55%,respectively,the difference of which was statistical significance(P<0.01).The detection rate of HBsAb in newborns after 6-month treatment(64.55%) was significantly better than that in 1-month newborns(22.72%)(P<0.01),and there were not significant adverse reactions in pregnant woman and newborn.Conclusions: HBIG in blocking the HBV transmission in mother-to-infant is effective and safe,which can be applied in clinic.
2014, 39(9): 1187-1189.
Abstract:
Objective: To explore the pathogenic bacteria distribution of bone and joint purulent infection and its drug resistance for providing the basis of antimicrobial treatment.Methods: The pathogenic bacteria from 418 samples of patients with bone and joint purulent infection were isolated and identified,and the antibiotics sensitivity tests were examined.Results: Two hundred and twelve strains gram-positive bacteria and 176 gram-negative bacteria were isolated form 418 samples.The detection rates of Staphylococcus aureus,Pseudomon asaeruginosa,Escherichia coli,Proteus mirabilis and Staphylococcus epidermidis were 38.28%,11.48%,8.13%,5.26% and 4.78%,respectively.Conclusions: The drug-resistant Staphylococcus aureus is the mainly pathogenic bacteria of bone and joint purulent infection.The antibiotics treatment should be taken according to the results of antibiotics sensitivity tests which can induce the resistance to antibiotics.
Objective: To explore the pathogenic bacteria distribution of bone and joint purulent infection and its drug resistance for providing the basis of antimicrobial treatment.Methods: The pathogenic bacteria from 418 samples of patients with bone and joint purulent infection were isolated and identified,and the antibiotics sensitivity tests were examined.Results: Two hundred and twelve strains gram-positive bacteria and 176 gram-negative bacteria were isolated form 418 samples.The detection rates of Staphylococcus aureus,Pseudomon asaeruginosa,Escherichia coli,Proteus mirabilis and Staphylococcus epidermidis were 38.28%,11.48%,8.13%,5.26% and 4.78%,respectively.Conclusions: The drug-resistant Staphylococcus aureus is the mainly pathogenic bacteria of bone and joint purulent infection.The antibiotics treatment should be taken according to the results of antibiotics sensitivity tests which can induce the resistance to antibiotics.
2014, 39(9): 1190-1192,1195.
Abstract:
Objective: To investigate the effects of 40 mg and 80 mg fluvastatin on the coronary artery plaques,and levels of serum lipids and high sensitive C-reactive protein(hs-CRP) in patients with coronary heart disease,and its safety.Methods: One hundred and twenty patients with coronary heart disease were randomly divided into A group(treatment with 80 mg fluvastatin every night),B group(treatment with 40 mg fluvastatin every night) and C group(treatment with other fluvastatin and hypolipidemic drugs)(40 cases each group),and the treatment course of all cases was 6 months.The computed tomography coronary angiography in all patients was examined to calculate the coronary artery plaques before and after treatment.The serum levels of total cholesterol(TC),triglyceride(TG),low density lipoprotein cholesterol(LDL-C),high density lipoprotein cholesterol(HDL-C),hs-CRP and liver function in all cases were measured.Results: The differences of the serum levels of TC,TG,LDL-C,HDL-C and hs-CRP between three groups before treatment were not statistical significance(P>0.05).Compared with before treatment,the serum levels of hs-CRP,TC,TG and LDL-C in A and B groups in 6 months after treatment decreased(P<0.01),but for the level of HDL-C,it increased(P<0.01).The level of LDL-C in A group after treatment was lower than that in B group(P<0.01).After treatment,the number of fatty plaques,and the number of fibre and calcified plaques in coronary artery of A and B groups decreased and increased,respectively,the differences of whose between three groups were not statistical significance(P>0.05).Conclusions: The treatment of coronary heart disease with fluvastatin can significantly reduce the serum levels of hs-CRP and blood lipid,inhibit inflammation,and stabilize and regress the plaque of coronary artery heart.The effect of A group is better than that of B group.
Objective: To investigate the effects of 40 mg and 80 mg fluvastatin on the coronary artery plaques,and levels of serum lipids and high sensitive C-reactive protein(hs-CRP) in patients with coronary heart disease,and its safety.Methods: One hundred and twenty patients with coronary heart disease were randomly divided into A group(treatment with 80 mg fluvastatin every night),B group(treatment with 40 mg fluvastatin every night) and C group(treatment with other fluvastatin and hypolipidemic drugs)(40 cases each group),and the treatment course of all cases was 6 months.The computed tomography coronary angiography in all patients was examined to calculate the coronary artery plaques before and after treatment.The serum levels of total cholesterol(TC),triglyceride(TG),low density lipoprotein cholesterol(LDL-C),high density lipoprotein cholesterol(HDL-C),hs-CRP and liver function in all cases were measured.Results: The differences of the serum levels of TC,TG,LDL-C,HDL-C and hs-CRP between three groups before treatment were not statistical significance(P>0.05).Compared with before treatment,the serum levels of hs-CRP,TC,TG and LDL-C in A and B groups in 6 months after treatment decreased(P<0.01),but for the level of HDL-C,it increased(P<0.01).The level of LDL-C in A group after treatment was lower than that in B group(P<0.01).After treatment,the number of fatty plaques,and the number of fibre and calcified plaques in coronary artery of A and B groups decreased and increased,respectively,the differences of whose between three groups were not statistical significance(P>0.05).Conclusions: The treatment of coronary heart disease with fluvastatin can significantly reduce the serum levels of hs-CRP and blood lipid,inhibit inflammation,and stabilize and regress the plaque of coronary artery heart.The effect of A group is better than that of B group.
2014, 39(9): 1193-1195.
Abstract:
Objective: To explore the effectiveness of intraoperative reposition senile proximal humeral fractures by using bridging fixation of plate.Methods: All patients were treated with locking proximal humerus plate.During the operation,first of all,after reposition the proximal end of fracture,locking the proximal end of plate with a locking screw for fixation the proximal end of fracture.then,reposition the distal end of fracture by using bridging fixation of plate.Results: All the fracture fragments were fast,effectively reposited.Radiographic review around 4 weeks,8 weeks,3 months and 6 months after the operation,the fracture was not displaced,the fixation was not failure.After 6 months,according to Neer functional score evaluation:excellent in 12 cases,good in 3 cases,fair in 2 cases,poor in 1 cases,the excellent and good rate was 83.3%.Conclusions: Senile proximal humeral fracture can be fast,effectively reposited by using bridging fixation of plate
Objective: To explore the effectiveness of intraoperative reposition senile proximal humeral fractures by using bridging fixation of plate.Methods: All patients were treated with locking proximal humerus plate.During the operation,first of all,after reposition the proximal end of fracture,locking the proximal end of plate with a locking screw for fixation the proximal end of fracture.then,reposition the distal end of fracture by using bridging fixation of plate.Results: All the fracture fragments were fast,effectively reposited.Radiographic review around 4 weeks,8 weeks,3 months and 6 months after the operation,the fracture was not displaced,the fixation was not failure.After 6 months,according to Neer functional score evaluation:excellent in 12 cases,good in 3 cases,fair in 2 cases,poor in 1 cases,the excellent and good rate was 83.3%.Conclusions: Senile proximal humeral fracture can be fast,effectively reposited by using bridging fixation of plate
2014, 39(9): 1196-1197,1200.
Abstract:
Objective: To explore the clinical efficiency of the preoperative neoadjuvant chemotherapy and radiotherapy combined with operation in the treatment of FIGO Ib-Ⅱb stage cervical carcinoma.Methods: Forty operation patients were treated with preoperative neoadjuvant chemotherapy and radiotherapy.the radical resections in the patients with cervical lesions more than 4 cm.preoperative massive hemorrhage treated with intracavitary brachytherapy after 3 weeks were implemented.The safety of neoadjuvant chemotherapy and radiotherapy was evaluated by the tumor size change,adverse reaction of chemotherapy and radiotherapy,operation difficulty change and postoperative pathological change.Results: The total effective rate and success rate of operation in the cervical carcinoma patients treated with neoadjuvant chemotherapy and radiotherapy were 82.5% and 100%,respectively.Conclusions: The neoadjuvant chemotherapy and radiotherapy combined with operation in treating the Ib2-Ⅱb stage cervical carcinoma is safe and effective.which can improve the operative effects and decrease the incidence of complications.
Objective: To explore the clinical efficiency of the preoperative neoadjuvant chemotherapy and radiotherapy combined with operation in the treatment of FIGO Ib-Ⅱb stage cervical carcinoma.Methods: Forty operation patients were treated with preoperative neoadjuvant chemotherapy and radiotherapy.the radical resections in the patients with cervical lesions more than 4 cm.preoperative massive hemorrhage treated with intracavitary brachytherapy after 3 weeks were implemented.The safety of neoadjuvant chemotherapy and radiotherapy was evaluated by the tumor size change,adverse reaction of chemotherapy and radiotherapy,operation difficulty change and postoperative pathological change.Results: The total effective rate and success rate of operation in the cervical carcinoma patients treated with neoadjuvant chemotherapy and radiotherapy were 82.5% and 100%,respectively.Conclusions: The neoadjuvant chemotherapy and radiotherapy combined with operation in treating the Ib2-Ⅱb stage cervical carcinoma is safe and effective.which can improve the operative effects and decrease the incidence of complications.
2014, 39(9): 1198-1200.
Abstract:
Objective: To investigate the curative effects of double-sided cone spiral mortar Zweymüller combined with PLUS-SL micro-invasive handle in the treatment of femoral head necrosis complicated with secondary osteoarthritis.Methods: Fifty-eight hips(50 cases) with femoral head necrosis complicated with secondary osteoarthritis were treated with double-sided cone spiral mortar Zweymüller combined with PLUS-SL micro-invasive handle.All acetabulums were lined with high cross linking polyethylene dislocation and ceramic ball head.All patients were followed up for 10 to 32 months.Results: The postoperative pain disappeared in all patients.The difference of the lengths of both legs was(1.2±0.51) cm,the postoperative Harris score was significantly higher than that of before operation(P<0.01).Conclusions: The treatment of femoral head necrosis complicated with secondary osteoarthritis with double-sided cone spiral mortar Zweymüller combined with PLUS-SL micro-invasive handle can improve the recovery of the joint function.
Objective: To investigate the curative effects of double-sided cone spiral mortar Zweymüller combined with PLUS-SL micro-invasive handle in the treatment of femoral head necrosis complicated with secondary osteoarthritis.Methods: Fifty-eight hips(50 cases) with femoral head necrosis complicated with secondary osteoarthritis were treated with double-sided cone spiral mortar Zweymüller combined with PLUS-SL micro-invasive handle.All acetabulums were lined with high cross linking polyethylene dislocation and ceramic ball head.All patients were followed up for 10 to 32 months.Results: The postoperative pain disappeared in all patients.The difference of the lengths of both legs was(1.2±0.51) cm,the postoperative Harris score was significantly higher than that of before operation(P<0.01).Conclusions: The treatment of femoral head necrosis complicated with secondary osteoarthritis with double-sided cone spiral mortar Zweymüller combined with PLUS-SL micro-invasive handle can improve the recovery of the joint function.
2014, 39(9): 1201-1203.
Abstract:
Objective: To compare the therapeutic effects of sufentanil and fentanyl on agitation of children treated with tonsillectomy under sevoflurane anesthesia.Methods: Sixty children treated with tonsillectomy under sevoflurane anesthesia were randomly divided into the A,B and C group(20 cases each group).The group B,C and A were intravenously injected with 2 μg/kg of fentanyl,0.2 μg/kg of sufentanil and the same volume of saline,respectively.Results: The incidence of severe agitation in group C was significantly lower than that in group A(P<0.01).The heart rate and arterial pressure before intubation and at 1 min after intubation were significantly lower than those in entering the operating room in group B and group C,and which was lower than those in group A(P<0.05 to P<0.01).Conclusions: The effects of the intravenous injecting sufentanil on agitation of children treated with tonsillectomy under sevoflurane anesthesia during the recovery period are good,which can significantly reduce the incidence of agitation,and do not affect the time of awakening and recovery of children.
Objective: To compare the therapeutic effects of sufentanil and fentanyl on agitation of children treated with tonsillectomy under sevoflurane anesthesia.Methods: Sixty children treated with tonsillectomy under sevoflurane anesthesia were randomly divided into the A,B and C group(20 cases each group).The group B,C and A were intravenously injected with 2 μg/kg of fentanyl,0.2 μg/kg of sufentanil and the same volume of saline,respectively.Results: The incidence of severe agitation in group C was significantly lower than that in group A(P<0.01).The heart rate and arterial pressure before intubation and at 1 min after intubation were significantly lower than those in entering the operating room in group B and group C,and which was lower than those in group A(P<0.05 to P<0.01).Conclusions: The effects of the intravenous injecting sufentanil on agitation of children treated with tonsillectomy under sevoflurane anesthesia during the recovery period are good,which can significantly reduce the incidence of agitation,and do not affect the time of awakening and recovery of children.
2014, 39(9): 1203-1205.
Abstract:
Objective: To investigate the clinical value of continuous lavage drainage of lateral ventricle in the treatment of intraventricular hemorrhage.Methods: Forty-six patients with intraventricular hemorrhage were randomly divided into the treatment group and control group.The treatment group and control group were treated with double lateral drainage combined with continuous urokinase lavage and urokinase injection,respectively.The clinical effects between two groups were compared.Results: The effective rate,time of clearing intraventricular hemorrhage,intracranial infection rate and hospitalization time in treatment group were better than those in control group(P<0.05 to P<0.01).Conclusions: Lateral ventricle lavage is an effective method in treating intraventricular hemorrhage.
Objective: To investigate the clinical value of continuous lavage drainage of lateral ventricle in the treatment of intraventricular hemorrhage.Methods: Forty-six patients with intraventricular hemorrhage were randomly divided into the treatment group and control group.The treatment group and control group were treated with double lateral drainage combined with continuous urokinase lavage and urokinase injection,respectively.The clinical effects between two groups were compared.Results: The effective rate,time of clearing intraventricular hemorrhage,intracranial infection rate and hospitalization time in treatment group were better than those in control group(P<0.05 to P<0.01).Conclusions: Lateral ventricle lavage is an effective method in treating intraventricular hemorrhage.
2014, 39(9): 1206-1208.
Abstract:
Objective: To investigate the cognition and high-risk factors of diabetic foot in diabetic patients.Methods: The cognition and high-risk factors of diabetic foot in 120 patients with type 2 diabetes were investigated.Results: The cognitive rate of the related knowledge of diabetic foot and awareness rate of foot care and shoe selection of patients were 63.3% and 45.0%,respectively.The differences of the cognitive rate of the related knowledge of diabetic foot and awareness rate of foot care and shoe selection between patients with disease duration more than or equal to 10 years and less than 10 years were not statistically significant(P>0.05).The abnormal incidence of left leg ankle brachial index(21.7%) was higher than that of right lower limb(11.7%)(P<0.05).The risk incidence of vibration threshold in left and right lower limb were 26.7% and 16.7%,respectively,the difference of which was not statistically significant(P>0.05).Conclusions: To improve the cognition and screen the high-risk factor of diabetic foot in diabetic patients can reduce the incidence of diabetic foot.
Objective: To investigate the cognition and high-risk factors of diabetic foot in diabetic patients.Methods: The cognition and high-risk factors of diabetic foot in 120 patients with type 2 diabetes were investigated.Results: The cognitive rate of the related knowledge of diabetic foot and awareness rate of foot care and shoe selection of patients were 63.3% and 45.0%,respectively.The differences of the cognitive rate of the related knowledge of diabetic foot and awareness rate of foot care and shoe selection between patients with disease duration more than or equal to 10 years and less than 10 years were not statistically significant(P>0.05).The abnormal incidence of left leg ankle brachial index(21.7%) was higher than that of right lower limb(11.7%)(P<0.05).The risk incidence of vibration threshold in left and right lower limb were 26.7% and 16.7%,respectively,the difference of which was not statistically significant(P>0.05).Conclusions: To improve the cognition and screen the high-risk factor of diabetic foot in diabetic patients can reduce the incidence of diabetic foot.
2014, 39(9): 1208-1210.
Abstract:
Objective: To explore the risk factors for burns in children between 0 to 14 years old in Fuyang and to provide scientific basis for the prevention.Methods: The multilevel hierarchy,epidemiological random sampling and a self-designed questionnaire were adopted to investigate the patients' gender,age,administrative village,months and time point of burn occurrence and the severity of the burn.Results: Among the 2 463 children investigated,pediatric burns were found in 125 of them,with a total prevalence rate of 5.1%;the male had a higher prevalence rate than the female(7.5% vs 2.8 %,P<0.05);the incidence of pediatric burns was the highest during the age of 1-3,which decreased gradually with the age increasing.The difference was statistically significant among each age group(P<0.01).The difference of pediatric burns in different villages was significant,from the incidence of 8.4% to 2.5%(P<0.01).Among the children with burns,mild burns accounted for 2.5% and moderate burns 1.5%.The highest incidence of burns was during 16:00-24:00(2.8%) and the highest incidence months were April to June(2.1%).Conclusions: The prevalence rate of pediatric burns from the ages of 1 to 14 in Fuyang rural area is 5.1%.Boys are the risk population;16:00-24:00 are the risk time points and April-June the risk months;infants and preschool children have a higher incidence of pediatric diseases.
Objective: To explore the risk factors for burns in children between 0 to 14 years old in Fuyang and to provide scientific basis for the prevention.Methods: The multilevel hierarchy,epidemiological random sampling and a self-designed questionnaire were adopted to investigate the patients' gender,age,administrative village,months and time point of burn occurrence and the severity of the burn.Results: Among the 2 463 children investigated,pediatric burns were found in 125 of them,with a total prevalence rate of 5.1%;the male had a higher prevalence rate than the female(7.5% vs 2.8 %,P<0.05);the incidence of pediatric burns was the highest during the age of 1-3,which decreased gradually with the age increasing.The difference was statistically significant among each age group(P<0.01).The difference of pediatric burns in different villages was significant,from the incidence of 8.4% to 2.5%(P<0.01).Among the children with burns,mild burns accounted for 2.5% and moderate burns 1.5%.The highest incidence of burns was during 16:00-24:00(2.8%) and the highest incidence months were April to June(2.1%).Conclusions: The prevalence rate of pediatric burns from the ages of 1 to 14 in Fuyang rural area is 5.1%.Boys are the risk population;16:00-24:00 are the risk time points and April-June the risk months;infants and preschool children have a higher incidence of pediatric diseases.
2014, 39(9): 1211-1213.
Abstract:
Objective: To investigate the clinical value of loop electrosurgical excision procedure(LEEP) in patients with severe cervical intraepithelial neoplasia(CIN Ⅲ) before hysterectomy.Methods: Seventy patients with CIN Ⅲ diagnosed by colposcopy were treated with LEEP before hysterectomy.The pathological differences between colposcopy,LEEP edge tissue and total hysterectomy tissue were compared.Results: The disaccord rate of the pathological results between colposcopy and LEEP edge tissue was 28.57%,and the pathology upgrading to infiltrating carcinoma in 5 cases were found,the upgrading rate of which was 7.14%.Thirty-nine cases were diagnosed chronic cervicitis after hysterectomy,and the normal rate was 55.71%.Among the 50 positive LEEP edge cases,23 cases were positive after hysterectomy,the positive rate of which was 46.00%.Among the 20 negative LEEP edge cases 8 cases were posititve affter hysterectomy after hysterectomy,the positive rate of which was 40.00%.The difference of the residual lesions risk of uterus between the positive and negative LEEP edge patients was not statistical significance(P>0.05).Conclusions: The multi-point biopsy under colposcope has the possibility of missed diagnosis in cervical lesions.The diagnostic LEEP in CIN Ⅲ patients should be implemented before total hysterectomy,otherwise hysterectomy is risk.
Objective: To investigate the clinical value of loop electrosurgical excision procedure(LEEP) in patients with severe cervical intraepithelial neoplasia(CIN Ⅲ) before hysterectomy.Methods: Seventy patients with CIN Ⅲ diagnosed by colposcopy were treated with LEEP before hysterectomy.The pathological differences between colposcopy,LEEP edge tissue and total hysterectomy tissue were compared.Results: The disaccord rate of the pathological results between colposcopy and LEEP edge tissue was 28.57%,and the pathology upgrading to infiltrating carcinoma in 5 cases were found,the upgrading rate of which was 7.14%.Thirty-nine cases were diagnosed chronic cervicitis after hysterectomy,and the normal rate was 55.71%.Among the 50 positive LEEP edge cases,23 cases were positive after hysterectomy,the positive rate of which was 46.00%.Among the 20 negative LEEP edge cases 8 cases were posititve affter hysterectomy after hysterectomy,the positive rate of which was 40.00%.The difference of the residual lesions risk of uterus between the positive and negative LEEP edge patients was not statistical significance(P>0.05).Conclusions: The multi-point biopsy under colposcope has the possibility of missed diagnosis in cervical lesions.The diagnostic LEEP in CIN Ⅲ patients should be implemented before total hysterectomy,otherwise hysterectomy is risk.
2014, 39(9): 1214-1215.
Abstract:
Objective: To investigate the effects and adverse reactions of zoledronic acid combined with chemotherapy in the treatment of malignant tumor with bone metastases.Methods: Sixty-four malignant tumor patients with bone metastases were randomly divided into the control group and trial group(32 cases each group).The control group and trial group were treated with single chemotherapy and zoledronic acid combined with chemotherapy,respectively.The chemotherapy regimens of two groups were the same.Results: The totally effective rates of curing pain in trial group and control group were 81.3% and 46.9%,respectively.The totally effective rates of controlling bone metastases in trial group and control group were 62.5% and 28.1%,respectively.The treatment effect in trial group was better than that in control group(P<0.01),no serious adverse reaction in two groups was found.Conclusions: The therapeutic effect of zoledronic acid combined with chemotherapy is better than that of single chemotherapy.The adverse reaction of zoledronic acid combined with chemotherapy is slight,and the patient is well-tolerated.
Objective: To investigate the effects and adverse reactions of zoledronic acid combined with chemotherapy in the treatment of malignant tumor with bone metastases.Methods: Sixty-four malignant tumor patients with bone metastases were randomly divided into the control group and trial group(32 cases each group).The control group and trial group were treated with single chemotherapy and zoledronic acid combined with chemotherapy,respectively.The chemotherapy regimens of two groups were the same.Results: The totally effective rates of curing pain in trial group and control group were 81.3% and 46.9%,respectively.The totally effective rates of controlling bone metastases in trial group and control group were 62.5% and 28.1%,respectively.The treatment effect in trial group was better than that in control group(P<0.01),no serious adverse reaction in two groups was found.Conclusions: The therapeutic effect of zoledronic acid combined with chemotherapy is better than that of single chemotherapy.The adverse reaction of zoledronic acid combined with chemotherapy is slight,and the patient is well-tolerated.
2014, 39(9): 1216-1218.
Abstract:
Objective: To explore the perioperative risks and preventive measures of pernicious placenta praevia.Methods: Thirty cases with pernicious placenta praevia and 32 cases with non-pernicious placenta praevia were divided into the study group and control group from 2010 to 2013,respectively.The preoperative ultrasound,preoperative bleeding rate,intraoperative blood loss,placenta implantation rate,uterus resection rate,intraoperative hemostatic measures,neonatal asphyxia and postoperative recovery time between two groups were analysed.Results: The difference of preoperative ultrasound in two groups was statistical significance(P<0.01).There was not significant difference in preoperative bleeding rate and neonatal asphyxia between two groups(P>0.05).The differences of intraoperative blood loss,total amount of blood transfusion,intraoperative vital signs placenta implantation rate,uterus resection rate and intraoperative hemostatic measures between two groups were statistically significant(P<0.01).The differences of postoperative body temperature and hospital stay in two groups were statistically significant(P<0.01),and the difference of postoperative hemoglobin recovery in two groups was not statistically significant(P>0.05).Conclusions: The perioperative risk of pernicious placenta praevia is great,which need some collaboration rescue measures of multidisciplinary to ensure the safety of motherhood and infant.
Objective: To explore the perioperative risks and preventive measures of pernicious placenta praevia.Methods: Thirty cases with pernicious placenta praevia and 32 cases with non-pernicious placenta praevia were divided into the study group and control group from 2010 to 2013,respectively.The preoperative ultrasound,preoperative bleeding rate,intraoperative blood loss,placenta implantation rate,uterus resection rate,intraoperative hemostatic measures,neonatal asphyxia and postoperative recovery time between two groups were analysed.Results: The difference of preoperative ultrasound in two groups was statistical significance(P<0.01).There was not significant difference in preoperative bleeding rate and neonatal asphyxia between two groups(P>0.05).The differences of intraoperative blood loss,total amount of blood transfusion,intraoperative vital signs placenta implantation rate,uterus resection rate and intraoperative hemostatic measures between two groups were statistically significant(P<0.01).The differences of postoperative body temperature and hospital stay in two groups were statistically significant(P<0.01),and the difference of postoperative hemoglobin recovery in two groups was not statistically significant(P>0.05).Conclusions: The perioperative risk of pernicious placenta praevia is great,which need some collaboration rescue measures of multidisciplinary to ensure the safety of motherhood and infant.
2014, 39(9): 1219-1220.
Abstract:
Objective: To evaluate the clinical efficacy of titanic elastic nailing fixation on long bone fractures in children after closed reduction.Methods: Sixty-seven children with long bone fractures were treated using titanic elastic nailing.Results: All the 67 cases were followed up from 3 to 18 months.No fracture redisplacement,nonunion or delayed union occurred.The average healing time was 6-8 weeks for the shaft of femur and tibiofibula,and 4-6 week for the humerus and shaft of radius.The internal fixation was removed 6 months later;the function of the affected limb and the neighboring joints were close to normal.Nail tail irritation and synovial sac formation occurred in 4 cases,which disappeared after removal of the implants.Conclusions: Titanic elastic nailing fixation is safe,effective and minimally invasive for treatment of children with long bone fracture with the advantages of faster healing and good functional recovery.The material deserves priority consideration for internal fixation.
Objective: To evaluate the clinical efficacy of titanic elastic nailing fixation on long bone fractures in children after closed reduction.Methods: Sixty-seven children with long bone fractures were treated using titanic elastic nailing.Results: All the 67 cases were followed up from 3 to 18 months.No fracture redisplacement,nonunion or delayed union occurred.The average healing time was 6-8 weeks for the shaft of femur and tibiofibula,and 4-6 week for the humerus and shaft of radius.The internal fixation was removed 6 months later;the function of the affected limb and the neighboring joints were close to normal.Nail tail irritation and synovial sac formation occurred in 4 cases,which disappeared after removal of the implants.Conclusions: Titanic elastic nailing fixation is safe,effective and minimally invasive for treatment of children with long bone fracture with the advantages of faster healing and good functional recovery.The material deserves priority consideration for internal fixation.
2014, 39(9): 1221-1222,1225.
Abstract:
Objective: To investigate the risk factors,clinical features and prognosis of acute exacerbation of chronic obstructive pulmonary disease(COPD).Methods: The etiology and treatment of 286 patients with COPD were retrospectively analyzed.Results: Among 226 patients,the respiratory infection and physical and chemical factors were the inducing factor and main factors of disease,respectively.The emotional stress,electrolyte disorder,insomnia,drug withdrawal,spontaneous pneumothorax and pulmonary embolism could aggravate the diseases,and the levels of C-reactive protein and neutrophil increased obviously in 226 patients.The FEV1.0 in 278 patients decreased.The risk of death in patients with multiple organ disease,multiple drug-resistant bacteria infection,repeated mechanical ventilation and hypoalbuminemia was large.Conclusions: Respiratory infection and physical and chemical factors are the main causes of the acute exacerbation of COPD.Clinical manifestations and laboratory examination results are inconsistent,the fatality rate of patients with complex conditions is high,which should be greatly paid attention to.
Objective: To investigate the risk factors,clinical features and prognosis of acute exacerbation of chronic obstructive pulmonary disease(COPD).Methods: The etiology and treatment of 286 patients with COPD were retrospectively analyzed.Results: Among 226 patients,the respiratory infection and physical and chemical factors were the inducing factor and main factors of disease,respectively.The emotional stress,electrolyte disorder,insomnia,drug withdrawal,spontaneous pneumothorax and pulmonary embolism could aggravate the diseases,and the levels of C-reactive protein and neutrophil increased obviously in 226 patients.The FEV1.0 in 278 patients decreased.The risk of death in patients with multiple organ disease,multiple drug-resistant bacteria infection,repeated mechanical ventilation and hypoalbuminemia was large.Conclusions: Respiratory infection and physical and chemical factors are the main causes of the acute exacerbation of COPD.Clinical manifestations and laboratory examination results are inconsistent,the fatality rate of patients with complex conditions is high,which should be greatly paid attention to.
2014, 39(9): 1223-1225.
Abstract:
Objective: To explore the efficacy of posterior corpectomy combined with intervertebral bone graft in the treatment of thoracolumbar burst fracture.Methods: Nineteen patients with thoracolumbar?burst?fractures were treated with posterior corpectomy combined with intervertebral bone graft.The X-ray and 3-D CT scanning in all cases were performed at postoperative 1 week,3 months,6 months and 12 months.The intervertebral height,intervertebral strut,periphery bone graft fusion,spinal canal decompression and spinal nerve function recovery of all patients were observed.Results: The operations in 19 patients were successful,all patients were followed up for 6 to 36 months.At postoperative 1 week,no obvious displacement in strut was observed in X-ray film,and part spinal nerve function recovered.At postoperative 3 months,no space-occupying lesion and vague interspace between the strut and periphery bone graft and adjacent vertebrae were observed by X-ray film and CT scanning.At postoperative 6 and 12 months,the continuous trabeculae formations between the strut and periphery bone graft and adjacent vertebrae in 18 cases,no continuous trabeculae formations between the strut and vertebrae and periphery bone graft union in 1 case and oblique strut(the obliquity at sagittal or coronal plane was less than 10°) in 1 case were detected by X-ray film and CT scanning.The Frankel grading in 19 cases were obviously improved.Conclusions: The posterior corpectomy combined with intervertebral bone graft can completely decompress,and be conducive to the spinal nerve function recovery.The strut bone graft can be conducive to the recovery of spinal stability,and reduce the possibility of the loosening and fracture of internal fixation.
Objective: To explore the efficacy of posterior corpectomy combined with intervertebral bone graft in the treatment of thoracolumbar burst fracture.Methods: Nineteen patients with thoracolumbar?burst?fractures were treated with posterior corpectomy combined with intervertebral bone graft.The X-ray and 3-D CT scanning in all cases were performed at postoperative 1 week,3 months,6 months and 12 months.The intervertebral height,intervertebral strut,periphery bone graft fusion,spinal canal decompression and spinal nerve function recovery of all patients were observed.Results: The operations in 19 patients were successful,all patients were followed up for 6 to 36 months.At postoperative 1 week,no obvious displacement in strut was observed in X-ray film,and part spinal nerve function recovered.At postoperative 3 months,no space-occupying lesion and vague interspace between the strut and periphery bone graft and adjacent vertebrae were observed by X-ray film and CT scanning.At postoperative 6 and 12 months,the continuous trabeculae formations between the strut and periphery bone graft and adjacent vertebrae in 18 cases,no continuous trabeculae formations between the strut and vertebrae and periphery bone graft union in 1 case and oblique strut(the obliquity at sagittal or coronal plane was less than 10°) in 1 case were detected by X-ray film and CT scanning.The Frankel grading in 19 cases were obviously improved.Conclusions: The posterior corpectomy combined with intervertebral bone graft can completely decompress,and be conducive to the spinal nerve function recovery.The strut bone graft can be conducive to the recovery of spinal stability,and reduce the possibility of the loosening and fracture of internal fixation.
2014, 39(9): 1226-1228.
Abstract:
Objective: To explore the clinical effects of the epidural anesthesia in labor analgesia,and its effects on stages of labor and pregnancy outcome of maternal and child.Methods: Two hundred and sixteen natural childbirth puerperas with vaginal delivery,full term,single fetus,vertex presentation and no pregnancy complications and anesthesia contraindications,were randomly divided into the observation group and control group.The labor analgesia in observation group and control group were treated with epidural block anesthesia and non-drug,respectively.The delivery pain,duration of second and third labor,postpartum hemorrhage and Apgar scoring of neonate in two groups were observed.Results: The degree of delivery pain in observation group was significantly lower than that in control group(P<0.01).The expansion speed of cervix in observation group were significantly faster than that in control group(P<0.01).The effect of epidural anesthesia on labor analgesia in observation group was better than that in control group,which could shorten the active stage and third stage of labor(P<0.01).The differences of postpartum bleeding and neonatal Apgar score between two groups were not statistical significance(P>0.05).Conclusions: The epidural anesthesia is an ideal method in labor analgesia,which can accelerate labor progress,and is safe and worthy of spreading.
Objective: To explore the clinical effects of the epidural anesthesia in labor analgesia,and its effects on stages of labor and pregnancy outcome of maternal and child.Methods: Two hundred and sixteen natural childbirth puerperas with vaginal delivery,full term,single fetus,vertex presentation and no pregnancy complications and anesthesia contraindications,were randomly divided into the observation group and control group.The labor analgesia in observation group and control group were treated with epidural block anesthesia and non-drug,respectively.The delivery pain,duration of second and third labor,postpartum hemorrhage and Apgar scoring of neonate in two groups were observed.Results: The degree of delivery pain in observation group was significantly lower than that in control group(P<0.01).The expansion speed of cervix in observation group were significantly faster than that in control group(P<0.01).The effect of epidural anesthesia on labor analgesia in observation group was better than that in control group,which could shorten the active stage and third stage of labor(P<0.01).The differences of postpartum bleeding and neonatal Apgar score between two groups were not statistical significance(P>0.05).Conclusions: The epidural anesthesia is an ideal method in labor analgesia,which can accelerate labor progress,and is safe and worthy of spreading.
2014, 39(9): 1228-1230.
Abstract:
Objective: To analyze the effects of modified Z shape palatopharyngoplasty in the treatment of obstructive sleep apnea hypopnea syndrome(OSAHS).Methods: Seventy-one patients with OSAHS were treated with modified Z shape palatopharyngoplasty.The clinical parameters before and after treatment and effects in all patients were observed.Results: Compared with before operation,the BMI,AHI,snoring loudness score,CT90 and ESS score in patients decreased significantly after operation(P<0.01),but for LSaO2,it significantly increased(P<0.01).Postoperative wound edema in 1 case,respiratory tract obstruction in 1 case and nasopharyngeal closure bad in 1 case were found,the incidence of which was 4.23%,and the patients alleviated in 2 to 4 days after treatment.The average following up time of all patients was(11±1.3) months.Forty-nine cases were cured,6 cases were excellent and 7 cases were effective,the total efficiency of which was 87.3%.Conclusions: The improved Z shape palatopharyngoplasty can effectively improve blood oxygen saturation,expand the velopharyngeal cavity ventilation area,keep the normal physiological state of pharynx mucosa and reduce the incidence of adverse reaction,which is worthy of clinical popularization.
Objective: To analyze the effects of modified Z shape palatopharyngoplasty in the treatment of obstructive sleep apnea hypopnea syndrome(OSAHS).Methods: Seventy-one patients with OSAHS were treated with modified Z shape palatopharyngoplasty.The clinical parameters before and after treatment and effects in all patients were observed.Results: Compared with before operation,the BMI,AHI,snoring loudness score,CT90 and ESS score in patients decreased significantly after operation(P<0.01),but for LSaO2,it significantly increased(P<0.01).Postoperative wound edema in 1 case,respiratory tract obstruction in 1 case and nasopharyngeal closure bad in 1 case were found,the incidence of which was 4.23%,and the patients alleviated in 2 to 4 days after treatment.The average following up time of all patients was(11±1.3) months.Forty-nine cases were cured,6 cases were excellent and 7 cases were effective,the total efficiency of which was 87.3%.Conclusions: The improved Z shape palatopharyngoplasty can effectively improve blood oxygen saturation,expand the velopharyngeal cavity ventilation area,keep the normal physiological state of pharynx mucosa and reduce the incidence of adverse reaction,which is worthy of clinical popularization.
2014, 39(9): 1231-1233.
Abstract:
Objective: To investigate the effects of dezocine analgesia on the incidence of the postoperative delirium in orthopedic elderly patients.Methods: Seventy more than 60 years old patients,who were scheduled by knee and hip arthroplasty were randomly into the dezocine analgesia group(DA group) and morphine analgesia group(MA group)(35 cases each group).The incidence of the postoperative delirium,visual analog scale(VAS) and adverse reactions between two groups were compared after operation(T1),and at 24 and 48 hours after operation(T2 and T3).Results: The difference of the incidence of delirium at T1 between two groups was not statistically significant(P>0.05).The differences of the incidences of nausea,vomiting and respiratory depression after operation between two groups were not statistically significant(P>0.05).The differences of the VAS scores at T1,T2 and T3 between two groups were not statistically significant(P>0.05).Conclusions: The effects of dezocine analgesia on the incidence of the postoperative delirium in orthopedic elderly patients are the same as that of morphine,which are less risks and adverse reactions.
Objective: To investigate the effects of dezocine analgesia on the incidence of the postoperative delirium in orthopedic elderly patients.Methods: Seventy more than 60 years old patients,who were scheduled by knee and hip arthroplasty were randomly into the dezocine analgesia group(DA group) and morphine analgesia group(MA group)(35 cases each group).The incidence of the postoperative delirium,visual analog scale(VAS) and adverse reactions between two groups were compared after operation(T1),and at 24 and 48 hours after operation(T2 and T3).Results: The difference of the incidence of delirium at T1 between two groups was not statistically significant(P>0.05).The differences of the incidences of nausea,vomiting and respiratory depression after operation between two groups were not statistically significant(P>0.05).The differences of the VAS scores at T1,T2 and T3 between two groups were not statistically significant(P>0.05).Conclusions: The effects of dezocine analgesia on the incidence of the postoperative delirium in orthopedic elderly patients are the same as that of morphine,which are less risks and adverse reactions.
2014, 39(9): 1236-1238.
Abstract:
Objective: To observe the clinical effects and safety of the pituitary adenoma resection by nasal transsphenoidal approach under microscope.Methods: The pituitary adenomas in 115 patients were resected by nasal transsphenoidal approach under microscope.The relationships between the size,endocrine type,resection range of the tumor and clinical effects,and the influence factors of the postoperative complications were retrospectively analyzed.Results: All patients were followed up for 1 to 2 years,81 cases were cured,20 cases were eased,12 cases recurred and 2 cases died.The cure rate of microadenoma was higher than that in large adenoma and huge adenoma(P<0.05).The cure rates of PRL adenoma,adrenocorticotropic hormone adenoma,growth hormone adenoma and mixed adenoma were higher than that in non-function adenoma(P<0.05).The cure rates in patients treated with total and subtotal excision were higher than that in patients with partial excision(P<0.05).The complications recurrence of the functional pituitary adenoma was sighificantly lower than that of the non functional pituitary adenoma.Conclusions: The clinical effects of the pituitary adenoma resection by nasal transsphenoidal approach are good,which are related to the size,functional type and excision range of tumor.
Objective: To observe the clinical effects and safety of the pituitary adenoma resection by nasal transsphenoidal approach under microscope.Methods: The pituitary adenomas in 115 patients were resected by nasal transsphenoidal approach under microscope.The relationships between the size,endocrine type,resection range of the tumor and clinical effects,and the influence factors of the postoperative complications were retrospectively analyzed.Results: All patients were followed up for 1 to 2 years,81 cases were cured,20 cases were eased,12 cases recurred and 2 cases died.The cure rate of microadenoma was higher than that in large adenoma and huge adenoma(P<0.05).The cure rates of PRL adenoma,adrenocorticotropic hormone adenoma,growth hormone adenoma and mixed adenoma were higher than that in non-function adenoma(P<0.05).The cure rates in patients treated with total and subtotal excision were higher than that in patients with partial excision(P<0.05).The complications recurrence of the functional pituitary adenoma was sighificantly lower than that of the non functional pituitary adenoma.Conclusions: The clinical effects of the pituitary adenoma resection by nasal transsphenoidal approach are good,which are related to the size,functional type and excision range of tumor.
2014, 39(9): 1259-1261.
Abstract:
Objective: To investigate the magnetic resonance imaging(MRI) features of placenta implantation.Methods: The MRI findings of placenta implantation in 7 cases were retrospectively analyzed,which included 4 cases treated with prenatally plain scan and 3 cases treated with postpartum plain and enhanced scan.Results: The boundary of placenta and myometrium in local region of 7 cases were unclear,which included 4 cases in the anterior wall of uterus,2 cases in the fundus of uterus and 1 case in the anterior wall and fundus of uterus.Multifocal low signal bands in placenta of 6 cases and flow void signals of multiple dilated tortuous vasculature in placenta of 5 cases were shown on T2-weighted images.Two cases with placenta previa were detected by prenatal examination,3 cases with strengthening placenta tissue were found by postpartum enhanced scan.Conclusions: MRI examination is the best way in diagnosing placenta implantation at the little value of Ultrasound examination.The unclear boundary of placenta and myometrium,placenta invading myometrium,low signal bands and flow void signals of multiple dilated tortuous vasculature hint the placenta implantation.
Objective: To investigate the magnetic resonance imaging(MRI) features of placenta implantation.Methods: The MRI findings of placenta implantation in 7 cases were retrospectively analyzed,which included 4 cases treated with prenatally plain scan and 3 cases treated with postpartum plain and enhanced scan.Results: The boundary of placenta and myometrium in local region of 7 cases were unclear,which included 4 cases in the anterior wall of uterus,2 cases in the fundus of uterus and 1 case in the anterior wall and fundus of uterus.Multifocal low signal bands in placenta of 6 cases and flow void signals of multiple dilated tortuous vasculature in placenta of 5 cases were shown on T2-weighted images.Two cases with placenta previa were detected by prenatal examination,3 cases with strengthening placenta tissue were found by postpartum enhanced scan.Conclusions: MRI examination is the best way in diagnosing placenta implantation at the little value of Ultrasound examination.The unclear boundary of placenta and myometrium,placenta invading myometrium,low signal bands and flow void signals of multiple dilated tortuous vasculature hint the placenta implantation.
2014, 39(9): 1262-1264.
Abstract:
Objective: To investigate the value of Color Doppler Ultrasound in the diagnosis of varicocele for guiding clinic.Methods: The Color Doppler data of 50 cases with varicocele were retrospectively analyzed.The inside diameter and reflux time of varicocele and testicular volume in all patients were recorded at quiet breathing and standing after Valsalva action,which was compared with healthy people.Results: Compared with the control group,the inside diameter of varicocele widened obviously(P<0.01).The varicocele contorted and presented grid,its reflux time lengthened after Valsalva action(P<0.01).The left testis volume of the patients shrunk obviously(P<0.01),the left varicocele was the most common.Conclusions: Color Doppler ultrasound is convenient,cheap,fast,repeatable and accurate in diagnosing varicocele,which is an important index in clinical therapy.
Objective: To investigate the value of Color Doppler Ultrasound in the diagnosis of varicocele for guiding clinic.Methods: The Color Doppler data of 50 cases with varicocele were retrospectively analyzed.The inside diameter and reflux time of varicocele and testicular volume in all patients were recorded at quiet breathing and standing after Valsalva action,which was compared with healthy people.Results: Compared with the control group,the inside diameter of varicocele widened obviously(P<0.01).The varicocele contorted and presented grid,its reflux time lengthened after Valsalva action(P<0.01).The left testis volume of the patients shrunk obviously(P<0.01),the left varicocele was the most common.Conclusions: Color Doppler ultrasound is convenient,cheap,fast,repeatable and accurate in diagnosing varicocele,which is an important index in clinical therapy.
2014, 39(9): 1265-1267.
Abstract:
Objective: To explore the diagnostic value of CT in hemangiolymphangioma.Methods: The CT imaging and clinical data of 4 patients with hemangiolymphangioma diagnosed by pathology were retrospectively analyzed.Results: One case in left upper middle mediastinum and 3 cases in left side of retroperitoneum were found.All lesions were irregular multi-separated cystic mass,the size of which was about 9.1 cm×4.2 cm to 21.6 cm×8.1 cm.The lesions with multi-rooms were infiltrative growth along the tissue space.Some tiny linear or cable vascular enhancement imaging in cystic mass in arterial phase were found,which were obvious in venous phase,and accompanied different level enhancement in septum.Conclusions: CT has important value in the diagnosis of hemangiolymphangioma.
Objective: To explore the diagnostic value of CT in hemangiolymphangioma.Methods: The CT imaging and clinical data of 4 patients with hemangiolymphangioma diagnosed by pathology were retrospectively analyzed.Results: One case in left upper middle mediastinum and 3 cases in left side of retroperitoneum were found.All lesions were irregular multi-separated cystic mass,the size of which was about 9.1 cm×4.2 cm to 21.6 cm×8.1 cm.The lesions with multi-rooms were infiltrative growth along the tissue space.Some tiny linear or cable vascular enhancement imaging in cystic mass in arterial phase were found,which were obvious in venous phase,and accompanied different level enhancement in septum.Conclusions: CT has important value in the diagnosis of hemangiolymphangioma.
2014, 39(9): 1271-1273,1276.
Abstract:
Objective: To analyze the the referral and tracking situation of patients with suspected tuberculosis and tuberculosis from non-PTB control institutions network report in Bengbu from 2008 to 2012 in order to provide the basis of strengthening the patient management.Methods: The referral,tracing and checking report in tuberculosis Management Information System of PTB patients reported by non-TB control institutions from Bengbu in 2008 to 2012 were investigated.The referral arrival rate,tracing arrival rate,total arrival rate and detection rate of PTB patients in 7 513 referral patients were analyzed.Results: The difference of the referral arrival rate in patients with suspected tuberculosis and tuberculosis from non-PTB control institutions network report in Bengbu from 2008 to 2012 was not statistical significance(P>0.05),the tracing arrival and total arrival rates in patients were a rising trend year by year(P<0.01),the overall arrival rate of the patients with suspected pulmonary tuberculosis and tuberculosis from non-PTB control institutions network report in each county and district was a rising trend year by year(P<0.01).The refusing to see a doctor(29.37%) and other reasons(27.57%) were the main causes of tracing non-arrival,follow by patients going out(20.36%),the patients with unknown or false information leading to unable to tract accounted for 17.84%.Conclusions: There is room for improving in the work of referring and tracing the patients with suspected tuberculosis and tuberculosis from non-PTB control institutions network report in Bengbu.Consolidating and improving the overall arrival rate,promoting the institutions health education,writing the complete report and improving the diagnostic capabilities of the non-PTB control institutions are the keys to increase arrival.
Objective: To analyze the the referral and tracking situation of patients with suspected tuberculosis and tuberculosis from non-PTB control institutions network report in Bengbu from 2008 to 2012 in order to provide the basis of strengthening the patient management.Methods: The referral,tracing and checking report in tuberculosis Management Information System of PTB patients reported by non-TB control institutions from Bengbu in 2008 to 2012 were investigated.The referral arrival rate,tracing arrival rate,total arrival rate and detection rate of PTB patients in 7 513 referral patients were analyzed.Results: The difference of the referral arrival rate in patients with suspected tuberculosis and tuberculosis from non-PTB control institutions network report in Bengbu from 2008 to 2012 was not statistical significance(P>0.05),the tracing arrival and total arrival rates in patients were a rising trend year by year(P<0.01),the overall arrival rate of the patients with suspected pulmonary tuberculosis and tuberculosis from non-PTB control institutions network report in each county and district was a rising trend year by year(P<0.01).The refusing to see a doctor(29.37%) and other reasons(27.57%) were the main causes of tracing non-arrival,follow by patients going out(20.36%),the patients with unknown or false information leading to unable to tract accounted for 17.84%.Conclusions: There is room for improving in the work of referring and tracing the patients with suspected tuberculosis and tuberculosis from non-PTB control institutions network report in Bengbu.Consolidating and improving the overall arrival rate,promoting the institutions health education,writing the complete report and improving the diagnostic capabilities of the non-PTB control institutions are the keys to increase arrival.
2014, 39(9): 1274-1276.
Abstract:
Objective: To analyze the prevalence of notifiable diseases in a tumor Hospital from 2010 to 2011,and provide basis for notifiable diseases' prevention and control.Methods: The report data of notifiable infectious diseases in 2011 was described,and compared with 2010 report.Results: Nine species including 3 719 cases of notifiable diseases were reported in the hospital in 2011.There were no A class infectious diseases;6 species,3 704 cases of B infectious diseases,which accounting for 99.60%;3 species,15 cases of C infectious diseases,which accounting for 0.40%.Compared with 2010,the variety of infectious diseases was not changed in 2011,and the number of cases was reduced 123 cases,there were statistical difference on infectious diseases constitute between the two years(P<0.05).The top three reported cases of notifiable diseases in 2011 were viral hepatitis,tuberculosis and syphilis respectively,and viral hepatitis was the most which accouting for 90.47%.The number of reported infectious diseases cases in January and March was more,which accounting for 13.50% and 11.37% respectively,while in September and October was less,accounting for 5.46% and 4.22%;The constitute ratio of major infectious diseases showed an increasing trend after the first reduction.Conclusions: Viral hepatitis is a major infectious disease in hospital,it is necessary to strengthen monitoring and control.
Objective: To analyze the prevalence of notifiable diseases in a tumor Hospital from 2010 to 2011,and provide basis for notifiable diseases' prevention and control.Methods: The report data of notifiable infectious diseases in 2011 was described,and compared with 2010 report.Results: Nine species including 3 719 cases of notifiable diseases were reported in the hospital in 2011.There were no A class infectious diseases;6 species,3 704 cases of B infectious diseases,which accounting for 99.60%;3 species,15 cases of C infectious diseases,which accounting for 0.40%.Compared with 2010,the variety of infectious diseases was not changed in 2011,and the number of cases was reduced 123 cases,there were statistical difference on infectious diseases constitute between the two years(P<0.05).The top three reported cases of notifiable diseases in 2011 were viral hepatitis,tuberculosis and syphilis respectively,and viral hepatitis was the most which accouting for 90.47%.The number of reported infectious diseases cases in January and March was more,which accounting for 13.50% and 11.37% respectively,while in September and October was less,accounting for 5.46% and 4.22%;The constitute ratio of major infectious diseases showed an increasing trend after the first reduction.Conclusions: Viral hepatitis is a major infectious disease in hospital,it is necessary to strengthen monitoring and control.
2014, 39(9): 1277-1279.
Abstract:
Objective: To investigate the anti-CCP and rheumatoid factor(RF) in the diagnosis of rheumatoid arthritis(RA) patients.Methods: Forty cases of patients with RA and 40 cases of patients with other autoimmune diseases and 40 health people(control group) were selected.The concentration of anti-CCP was determined by electrochemical luminescence analysis and the concentration of RF was determined by chemical analysis,diagnostic sensitivity and specificity of anti-CCP antibodies and RF in RA were compared.Results: The anti-CCP content in the serum of RA patients was found distinctly higher than the control group and non-RA group(P<0.01),control group and non-RA group showed no significant difference with the level of anti-CCP antibody(P>0.05).The sensitivity of anti-CCP antibody and RF was 97.50% and 83.75%,there was significant difference between them(P<0.01).The specificity of anti-CCP antibody and RF was 65.0% and 67.5%,there was no significant difference between them(P>0.05).The specificity and sensitivity of combined detection of anti-CCP and RF were 98.75% and 82.50%.Conclusions: Detection of anti-CCP in Serum has a great value for diagnosis of RA and could be an ideal serological data for diagnosis of RA.Combined detection of anti-CCP antibody and RF could increase the diagnostic specificity and sensitivity.
Objective: To investigate the anti-CCP and rheumatoid factor(RF) in the diagnosis of rheumatoid arthritis(RA) patients.Methods: Forty cases of patients with RA and 40 cases of patients with other autoimmune diseases and 40 health people(control group) were selected.The concentration of anti-CCP was determined by electrochemical luminescence analysis and the concentration of RF was determined by chemical analysis,diagnostic sensitivity and specificity of anti-CCP antibodies and RF in RA were compared.Results: The anti-CCP content in the serum of RA patients was found distinctly higher than the control group and non-RA group(P<0.01),control group and non-RA group showed no significant difference with the level of anti-CCP antibody(P>0.05).The sensitivity of anti-CCP antibody and RF was 97.50% and 83.75%,there was significant difference between them(P<0.01).The specificity of anti-CCP antibody and RF was 65.0% and 67.5%,there was no significant difference between them(P>0.05).The specificity and sensitivity of combined detection of anti-CCP and RF were 98.75% and 82.50%.Conclusions: Detection of anti-CCP in Serum has a great value for diagnosis of RA and could be an ideal serological data for diagnosis of RA.Combined detection of anti-CCP antibody and RF could increase the diagnostic specificity and sensitivity.
2014, 39(9): 1280-1282.
Abstract:
Objective: To investigate the correlations of the levels of homocysteine(Hcy) and high-sensitive C-reactive protein(hs-CRP) and cerebral infarction.Methods: One hundred and twenty patients with cerebral infarction(including 72 cases complicated with hypertension and 48 cases complicated without hypertension) and 130 healthy people were divided into the experiment group and control group,respectively.The levels of Hcy and hs-CRP of all cases was detected.Results: The levels of Hcy and hs-CRP in experiment group(22.1±6.3)mg/L and(9.4±2.6)mg/L were higher than those in control group(10.4±2.5)mg/L and(1.8±0.8)mg/L(P<0.01).The levels of Hcy and hs-CRP in cerebral infarction patients complicated with hypertension((31.4±8.5)mg/L and(13.7±4.9)mg/L were higher than those in cerebral infarction patients complicated without hypertension(23.4±4.6)mg/L and(10.7±4.3) mg/L(P<0.01).Conclusions: The levels of Hcy and hs-CRP are closely related with the occurrence and development of cerebral infarction,which has importantly clinical value in cerebral infarction patients.
Objective: To investigate the correlations of the levels of homocysteine(Hcy) and high-sensitive C-reactive protein(hs-CRP) and cerebral infarction.Methods: One hundred and twenty patients with cerebral infarction(including 72 cases complicated with hypertension and 48 cases complicated without hypertension) and 130 healthy people were divided into the experiment group and control group,respectively.The levels of Hcy and hs-CRP of all cases was detected.Results: The levels of Hcy and hs-CRP in experiment group(22.1±6.3)mg/L and(9.4±2.6)mg/L were higher than those in control group(10.4±2.5)mg/L and(1.8±0.8)mg/L(P<0.01).The levels of Hcy and hs-CRP in cerebral infarction patients complicated with hypertension((31.4±8.5)mg/L and(13.7±4.9)mg/L were higher than those in cerebral infarction patients complicated without hypertension(23.4±4.6)mg/L and(10.7±4.3) mg/L(P<0.01).Conclusions: The levels of Hcy and hs-CRP are closely related with the occurrence and development of cerebral infarction,which has importantly clinical value in cerebral infarction patients.
2014, 39(9): 1288-1290.
Abstract:
Objective: To determine the clinical effects of local insulin injection combined with synthetic dressing on treatment of stage Ⅲ pressure sore in diabetic patients.Methods: A total of 32 cases,which had placed on admission with stage Ⅲ pressure sore were randomly divided into two groups.The patients in control group were received synthetic dressing on the basis of routine nursing and diet.The patients in experimental group were received insulin injection combined with synthetic dressing on the basis of routine nursing and diet.The clinical effects were compared after 21-day observation.Results: The average time of wound healing in experimental group was significantly lower than in control group(P<0.01),the wound healing rates in different periods were also significantly higher than in control group(P<0.05 to P<0.01).At the same time,the blood sugar level in experimental group had no obvious change after local application of insulin.Conclusions: Local insulin injection combined with synthetic dressing can reduce the healing time of stage Ⅲ pressure sore,meanwhile it is economic,safe,and no side effects.
Objective: To determine the clinical effects of local insulin injection combined with synthetic dressing on treatment of stage Ⅲ pressure sore in diabetic patients.Methods: A total of 32 cases,which had placed on admission with stage Ⅲ pressure sore were randomly divided into two groups.The patients in control group were received synthetic dressing on the basis of routine nursing and diet.The patients in experimental group were received insulin injection combined with synthetic dressing on the basis of routine nursing and diet.The clinical effects were compared after 21-day observation.Results: The average time of wound healing in experimental group was significantly lower than in control group(P<0.01),the wound healing rates in different periods were also significantly higher than in control group(P<0.05 to P<0.01).At the same time,the blood sugar level in experimental group had no obvious change after local application of insulin.Conclusions: Local insulin injection combined with synthetic dressing can reduce the healing time of stage Ⅲ pressure sore,meanwhile it is economic,safe,and no side effects.
2014, 39(9): 1291-1292,1295.
Abstract:
Objective: To investigate the disease uncertainty and quality of life of patients with type 2 diabetes,and explore the effects of disease uncertainty on their quality of life.Methods: Sixty patients with type 2 diabetes were investigated using Mishel's uncertainty in illness and diabetes specific quality of life scale,and the result of which was analyzed.Results: The total scores of disease uncertainty in all cases were(88.64±12.65),which was medium level.The scores of quality of life in all cases were(62.12±10.53).The levels of disease uncertainty in patients were negatively correlated to the total scores of their quality of life and the score of their social dimension(P<0.05).Conclusions: Clinical medical staff and community workers should strengthen the diabetic knowledge education,which can decrease the level of disease uncertainty in patients with type 2 diabetes and improve their quality of life.
Objective: To investigate the disease uncertainty and quality of life of patients with type 2 diabetes,and explore the effects of disease uncertainty on their quality of life.Methods: Sixty patients with type 2 diabetes were investigated using Mishel's uncertainty in illness and diabetes specific quality of life scale,and the result of which was analyzed.Results: The total scores of disease uncertainty in all cases were(88.64±12.65),which was medium level.The scores of quality of life in all cases were(62.12±10.53).The levels of disease uncertainty in patients were negatively correlated to the total scores of their quality of life and the score of their social dimension(P<0.05).Conclusions: Clinical medical staff and community workers should strengthen the diabetic knowledge education,which can decrease the level of disease uncertainty in patients with type 2 diabetes and improve their quality of life.
2014, 39(9): 1293-1295.
Abstract:
Objective: To explore the effects of synchronous health education of family member on the quality of life in patients with chronic renal insufficiency.Methods: Sixty patients with chronic renal insufficiency were randomly divided into control group and observation group.All patients were educated with routine instruction,the observation group were additionally educated with synchronous health education of family member.The quality of life of two groups were analyzed by SF-36 scale.Results: After health education,the quality of life in all patients were significantly improved(P<0.01),the improvement of the quality of life in observation group was significantly better than that in control group(P<0.01).Conclusions: The synchronous health education of family member can significantly improve the living condition,strengthen the knowledge and self-care ability,promote better treatment and care and improve the quality of life of patients with chronic renal insufficiency.
Objective: To explore the effects of synchronous health education of family member on the quality of life in patients with chronic renal insufficiency.Methods: Sixty patients with chronic renal insufficiency were randomly divided into control group and observation group.All patients were educated with routine instruction,the observation group were additionally educated with synchronous health education of family member.The quality of life of two groups were analyzed by SF-36 scale.Results: After health education,the quality of life in all patients were significantly improved(P<0.01),the improvement of the quality of life in observation group was significantly better than that in control group(P<0.01).Conclusions: The synchronous health education of family member can significantly improve the living condition,strengthen the knowledge and self-care ability,promote better treatment and care and improve the quality of life of patients with chronic renal insufficiency.
2014, 39(9): 1296-1298.
Abstract:
Objective: To observe the effects of the psychological and behavioral intervention on the compliance,mental health and blood pressure control of patients with essential hypertension.Methods: One hundred and two patients with essential hypertension were randomly divided into the control group(n=52) and observation group(n=50),the control group were treated with routine nursing and the observation group were treated with and psychological and behavior intervention according to the patients,respectively.The compliance,mental health and blood pressure control between two groups were analyzed in 6 months after treatment.Results: After 6-month psychological and behavioral intervention,the blood pressure in the observation group was significantly lower than that in the control group(P<0.01),the mental health improvement in the observation group was significantly better than that in the control group(P<0.05 to P<0.01).Conclusions: Psychological and behavioral intervention for patients can effectively control the blood pressure,improve compliance and level of mental health.
Objective: To observe the effects of the psychological and behavioral intervention on the compliance,mental health and blood pressure control of patients with essential hypertension.Methods: One hundred and two patients with essential hypertension were randomly divided into the control group(n=52) and observation group(n=50),the control group were treated with routine nursing and the observation group were treated with and psychological and behavior intervention according to the patients,respectively.The compliance,mental health and blood pressure control between two groups were analyzed in 6 months after treatment.Results: After 6-month psychological and behavioral intervention,the blood pressure in the observation group was significantly lower than that in the control group(P<0.01),the mental health improvement in the observation group was significantly better than that in the control group(P<0.05 to P<0.01).Conclusions: Psychological and behavioral intervention for patients can effectively control the blood pressure,improve compliance and level of mental health.
2014, 39(9): 1299-1301.
Abstract:
Objective: To investigate the effect of precise filtering infusion in reducing the infusion reaction and phlebitis induced by anti-cancer adjuvant drugs.Methods: A total of 306 cancer patients receiving intravenous infusion of anti-cancer adjuvant drugs were randomly divided into observation group(150 cases) and control group(156 cases).The patients in the observation group used disposable precise filtering infusion apparatus and the patients in the control group ordinary syringe injection.The incidence of infusion reaction and phlebitis in the two groups was observed and compared.Results: The total incidence of infusion reaction was 6.7% and 21.1% in the observation group and the control group,respectively;the total incidence of phlebitis was 7.3% and 26.9% in the observation group and the control group,respectively.The incidence of infusion reaction and phlebitis in the observation group was significantly lower than that in the control group(P<0.05 to P<0.01);the phlebitis in the observation group was relieved significantly(P<0.01).Conclusions: Application of precise filtering infusion apparatus can effectively reduce the occurrence of infusion reaction and phlebitis induced by intravenous injection of anti-cancer adjuvant drugs.
Objective: To investigate the effect of precise filtering infusion in reducing the infusion reaction and phlebitis induced by anti-cancer adjuvant drugs.Methods: A total of 306 cancer patients receiving intravenous infusion of anti-cancer adjuvant drugs were randomly divided into observation group(150 cases) and control group(156 cases).The patients in the observation group used disposable precise filtering infusion apparatus and the patients in the control group ordinary syringe injection.The incidence of infusion reaction and phlebitis in the two groups was observed and compared.Results: The total incidence of infusion reaction was 6.7% and 21.1% in the observation group and the control group,respectively;the total incidence of phlebitis was 7.3% and 26.9% in the observation group and the control group,respectively.The incidence of infusion reaction and phlebitis in the observation group was significantly lower than that in the control group(P<0.05 to P<0.01);the phlebitis in the observation group was relieved significantly(P<0.01).Conclusions: Application of precise filtering infusion apparatus can effectively reduce the occurrence of infusion reaction and phlebitis induced by intravenous injection of anti-cancer adjuvant drugs.
2014, 39(9): 1304-1307.
Abstract:
Objective: To investigate the effects of prospective nursing on the quality of life and negative emotions in patients with acute myocardial infarction,and provide the reference for clinical nursing.Methods: One hundred and twenty patients with acute myocardial infarction were randomly divided into the observation group and control group(60 cases each group).The control group and observation group were treated with conventional nursing and prospective nursing,respectively.The quality of life and improvement of negative emotion between two groups were compared.Results: The scores of SDS in observation group were lower than those in control group(P<0.01).The scores of physical function,psychological function and social function in observation group were higher than those in control group(P<0.05).Conclusions: Prospective nursing can reduce the anxiety and depression of patients,and improve their quality of life,which is worthy of clinical application.
Objective: To investigate the effects of prospective nursing on the quality of life and negative emotions in patients with acute myocardial infarction,and provide the reference for clinical nursing.Methods: One hundred and twenty patients with acute myocardial infarction were randomly divided into the observation group and control group(60 cases each group).The control group and observation group were treated with conventional nursing and prospective nursing,respectively.The quality of life and improvement of negative emotion between two groups were compared.Results: The scores of SDS in observation group were lower than those in control group(P<0.01).The scores of physical function,psychological function and social function in observation group were higher than those in control group(P<0.05).Conclusions: Prospective nursing can reduce the anxiety and depression of patients,and improve their quality of life,which is worthy of clinical application.
Email
RSS