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2015 Vol. 40, No. 8
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2015, 40(8): 989-991.
doi: 10.13898/j.cnki.issn.1000-2200.2015.08.001
Abstract:
Objective:To investigate the expression of serum soluble B7-H4(sB7-H4)in patients with malignant lymphoma(ML),and its clinical significance.Methods:The serum levels of sB7-H4 in 71 cases with ML(including 59 primary patients and 12 recurrent patients) and 40 healthy people were detected by ELISA.The protein expressions of sB7-H4 in 30 cases of lymphoma tissue and 10 cases of lymphocyte hyperplasia tissue were detected by immunohistochemistry.Results:The serum levels of sB7-H4 in patients with non-Hodgkin lymphoma(NHL) and Hodgkin lymphoma(HL) were singnificantly higher than that in healthy control group(P<0.01).The serum level of B7-H4 in NHL group was higher than that in HL group(P<0.05).The serum level of sB7-H4 in primary group was significantly lower than that in recurrent group,and was significantly higher than that in healthy control group(P<0.01).The immunohistochemistry results showed that the positive rate of sB7-H4 in lymphoma tissue was higher than that in lymphocyte hyperplasia tissue(P<0.05).Conclusions:The serum expression of sB7-H4 in ML patients is high,which can provide a new tumor marker in the accessory diagnosis and prognosis of lymphoma.
Objective:To investigate the expression of serum soluble B7-H4(sB7-H4)in patients with malignant lymphoma(ML),and its clinical significance.Methods:The serum levels of sB7-H4 in 71 cases with ML(including 59 primary patients and 12 recurrent patients) and 40 healthy people were detected by ELISA.The protein expressions of sB7-H4 in 30 cases of lymphoma tissue and 10 cases of lymphocyte hyperplasia tissue were detected by immunohistochemistry.Results:The serum levels of sB7-H4 in patients with non-Hodgkin lymphoma(NHL) and Hodgkin lymphoma(HL) were singnificantly higher than that in healthy control group(P<0.01).The serum level of B7-H4 in NHL group was higher than that in HL group(P<0.05).The serum level of sB7-H4 in primary group was significantly lower than that in recurrent group,and was significantly higher than that in healthy control group(P<0.01).The immunohistochemistry results showed that the positive rate of sB7-H4 in lymphoma tissue was higher than that in lymphocyte hyperplasia tissue(P<0.05).Conclusions:The serum expression of sB7-H4 in ML patients is high,which can provide a new tumor marker in the accessory diagnosis and prognosis of lymphoma.
2015, 40(8): 992-994.
doi: 10.13898/j.cnki.issn.1000-2200.2015.08.002
Abstract:
Objective:To investigate the suitable dosages of ligustrazine with good protective effect on ischemic skin flap.Methods:The Japanese big ear white rabbits were randomly divided into four groups.The 8 cm×2 cm random flap in the rabbit back was designed,cut and stripped,and the rabbits were stitched in situ.Group B,C and D were treated with 15,30 and 60 mg/kg of ligustrazine after operation,respectively,and the group A were treatment with 4 ml/kg of 0.9% sodium chloride injection.Rabbits were sacrificed after 7 days of operation,the flap survival area was measured,the relationship between different concentrations ligustrazine and flap survival was analyzed.Results:The distal necrosis and proximal survival of flap was found after days 7 operation.With the increasing of drug dosages,the flap survival area and average survival rate increased.The flap survival area and average survival in group C and D were higher than those in group A and B(P<0.05 to P<0.01),the differences of which between group A and B,and between group C and D were not statistically significant(P>0.05).Conclusions:Appropriate dose of ligustrazine can improve the survival rate of ischemic skin flap.
Objective:To investigate the suitable dosages of ligustrazine with good protective effect on ischemic skin flap.Methods:The Japanese big ear white rabbits were randomly divided into four groups.The 8 cm×2 cm random flap in the rabbit back was designed,cut and stripped,and the rabbits were stitched in situ.Group B,C and D were treated with 15,30 and 60 mg/kg of ligustrazine after operation,respectively,and the group A were treatment with 4 ml/kg of 0.9% sodium chloride injection.Rabbits were sacrificed after 7 days of operation,the flap survival area was measured,the relationship between different concentrations ligustrazine and flap survival was analyzed.Results:The distal necrosis and proximal survival of flap was found after days 7 operation.With the increasing of drug dosages,the flap survival area and average survival rate increased.The flap survival area and average survival in group C and D were higher than those in group A and B(P<0.05 to P<0.01),the differences of which between group A and B,and between group C and D were not statistically significant(P>0.05).Conclusions:Appropriate dose of ligustrazine can improve the survival rate of ischemic skin flap.
2015, 40(8): 994-997,1001.
doi: 10.13898/j.cnki.issn.1000-2200.2015.08.003
Abstract:
Objective:To explore the apoptosis-inducing effects of the application of the resveratrol(RES)combined with paclitaxel(PTX)on lung cancer cell line PC9,and its proable mechanism.Methods:After the PC9 cells were co-cultured with the single and combination of different concentrations two drugs,the anti-proliferative effects of drugs were measured using MTT,the cell cycle distribution and apoptosis were detected by flow cytometry,and the protein levels of Caspase-3,Bcl-2 and Bax were detected by western blotting.Results:The effects of RES and PTX on the inhibiting the prolification of PC9 cells were the time- and concentrate-dependent manner.The inhibition rate of RES combined with paclitaxel was higher than that of single RES or PTX use(P<0.01).The single use of RES or PTX could induce the apoptosis and block G0/G1 phase in PC9 cells,and the effect of which was significantly enhanced when two drugs were combined(P<0.01).Western blot assay showed that the changes of Caspase-3,Bcl-2 and Bax after the joint use of RES and PTX were significantly more than that of the single drug use.Conclusions:Both RES and PTX can inhibit the proliferation,induce apoptosis,block G0/G1 phase and increase the Caspase-3 activity of human lung cancer PC9 cells.The combined use of RES and PTX has synergistic effect,which can significantly promote the cell apoptosis,and the mechanism may be related to the upregulation of Bcl-2 and downregulation of Bax.
Objective:To explore the apoptosis-inducing effects of the application of the resveratrol(RES)combined with paclitaxel(PTX)on lung cancer cell line PC9,and its proable mechanism.Methods:After the PC9 cells were co-cultured with the single and combination of different concentrations two drugs,the anti-proliferative effects of drugs were measured using MTT,the cell cycle distribution and apoptosis were detected by flow cytometry,and the protein levels of Caspase-3,Bcl-2 and Bax were detected by western blotting.Results:The effects of RES and PTX on the inhibiting the prolification of PC9 cells were the time- and concentrate-dependent manner.The inhibition rate of RES combined with paclitaxel was higher than that of single RES or PTX use(P<0.01).The single use of RES or PTX could induce the apoptosis and block G0/G1 phase in PC9 cells,and the effect of which was significantly enhanced when two drugs were combined(P<0.01).Western blot assay showed that the changes of Caspase-3,Bcl-2 and Bax after the joint use of RES and PTX were significantly more than that of the single drug use.Conclusions:Both RES and PTX can inhibit the proliferation,induce apoptosis,block G0/G1 phase and increase the Caspase-3 activity of human lung cancer PC9 cells.The combined use of RES and PTX has synergistic effect,which can significantly promote the cell apoptosis,and the mechanism may be related to the upregulation of Bcl-2 and downregulation of Bax.
2015, 40(8): 998-1001.
doi: 10.13898/j.cnki.issn.1000-2200.2015.08.004
Abstract:
Objective:To explore the effects of sinomenine combined with 5-fluomuracil(5-Fu) on the proliferation of human gastric gland carcinoma cell line SGC 7901 and expressions of Bcl-2,Bax and COX-2.Methods:The human gastric gland carcinoma cell line SGC 7901 was cultured in vitro,which was divided into the control group,5-Fu group(50 mg/L),low concentration sinomenine group(1.25 mmol/L),medium concentration sinomenine group(2.5 mmol/L),high concentration sinomenine group(5 mmol/L) and combination group(25 mg/L of 5-Fu and 2.5 mmol/L of sinomenine).The proliferation of SGC7901 cells was detected by MTT,the cell cycle and apoptosis rate were determined by flow cytometry,and the expressions of Bcl-2,Bax and COX-2 were detected by immunohistochemistry.Results:Sinomenine could inhibit the proliferation of SGC7901 cells after 24 h,48 h and 72 h of treatment,which was dose- and time-dependent,and the treatment with sinomenine combined with 5-Fu could strengthen the inhibitory effects(P<0.05 to P<0.01).Compared with the control group,the apoptosis rates in 5-Fu group,sinomenine groups and combination group increased obviously(P<0.01),and the apoptosis rate in combination group was significantly lower than that in single drug group(P<0.05 to P<0.01).The positive expressions of Bcl-2 and COX-2 in the control group,and the sinomenine group,5-Fu group and combination group were strong and weak,respectively,the differences of whose were statistical significance(P<0.05 to P<0.01).The positive rates of Bcl-2 and COX-2 expressions in combination group were lower than those in single drug group(P<0.01 ).The positive expression of Bax in the control group,and the sinomenine group,5-Fu group and combination group were weak and strong,respectively,the differences of whose were statistically significant(P<0.01).The positive rate of Bax expression in combination group was higher than that in single drug group(P<0.01).Conclusions:Sinomenine combined with 5-Fu can enhance the inhibitory effect on SGC7901 cells proliferation,which can further upregulate the expression of Bax,and downregulate the expressions of Bcl-2 and COX-2 protein.
Objective:To explore the effects of sinomenine combined with 5-fluomuracil(5-Fu) on the proliferation of human gastric gland carcinoma cell line SGC 7901 and expressions of Bcl-2,Bax and COX-2.Methods:The human gastric gland carcinoma cell line SGC 7901 was cultured in vitro,which was divided into the control group,5-Fu group(50 mg/L),low concentration sinomenine group(1.25 mmol/L),medium concentration sinomenine group(2.5 mmol/L),high concentration sinomenine group(5 mmol/L) and combination group(25 mg/L of 5-Fu and 2.5 mmol/L of sinomenine).The proliferation of SGC7901 cells was detected by MTT,the cell cycle and apoptosis rate were determined by flow cytometry,and the expressions of Bcl-2,Bax and COX-2 were detected by immunohistochemistry.Results:Sinomenine could inhibit the proliferation of SGC7901 cells after 24 h,48 h and 72 h of treatment,which was dose- and time-dependent,and the treatment with sinomenine combined with 5-Fu could strengthen the inhibitory effects(P<0.05 to P<0.01).Compared with the control group,the apoptosis rates in 5-Fu group,sinomenine groups and combination group increased obviously(P<0.01),and the apoptosis rate in combination group was significantly lower than that in single drug group(P<0.05 to P<0.01).The positive expressions of Bcl-2 and COX-2 in the control group,and the sinomenine group,5-Fu group and combination group were strong and weak,respectively,the differences of whose were statistical significance(P<0.05 to P<0.01).The positive rates of Bcl-2 and COX-2 expressions in combination group were lower than those in single drug group(P<0.01 ).The positive expression of Bax in the control group,and the sinomenine group,5-Fu group and combination group were weak and strong,respectively,the differences of whose were statistically significant(P<0.01).The positive rate of Bax expression in combination group was higher than that in single drug group(P<0.01).Conclusions:Sinomenine combined with 5-Fu can enhance the inhibitory effect on SGC7901 cells proliferation,which can further upregulate the expression of Bax,and downregulate the expressions of Bcl-2 and COX-2 protein.
2015, 40(8): 1002-1004.
doi: 10.13898/j.cnki.issn.1000-2200.2015.08.005
Abstract:
Objective:To investigate the effects of modified wenjing decoction in the treatment of primary dysmenorrhea.Methods:Ninty-one patients with primary dysmenorrhea were randomly divided into the observation group(46 cases) and control group(45 cases).The observation group and control group were treated with modified wenjing decoction one dose a day 1 week before menstruation and ibuprofen sustained release capsule one capsule per half-day by oral,respectively.All cases were consecutively treated for 3 courses(1 week for 1 course).Results:The total effective rate in observational group was 84.8%,which was significantly higher than that in control group(64.4%)(P<0.01).Conclusions:Modified wenjing is an effective therapy for primary dysmenorrhea.
Objective:To investigate the effects of modified wenjing decoction in the treatment of primary dysmenorrhea.Methods:Ninty-one patients with primary dysmenorrhea were randomly divided into the observation group(46 cases) and control group(45 cases).The observation group and control group were treated with modified wenjing decoction one dose a day 1 week before menstruation and ibuprofen sustained release capsule one capsule per half-day by oral,respectively.All cases were consecutively treated for 3 courses(1 week for 1 course).Results:The total effective rate in observational group was 84.8%,which was significantly higher than that in control group(64.4%)(P<0.01).Conclusions:Modified wenjing is an effective therapy for primary dysmenorrhea.
2015, 40(8): 1005-1007.
doi: 10.13898/j.cnki.issn.1000-2200.2015.08.006
Abstract:
Objective:To compare the clinical effects of the endoscopic thyroidectomy by breast approach and conventional thyroidectomy in the treatment of benign thyroid disease.Methods:Among 60 patients with benign thyroid disease,20 cases were treated with the endoscopic thyroidectomy by breast approach(endoscopy group),35 cases were treated with conventional thyroidectomy(convention group).The operative time,intraoperative blood loss,postoperative drainage flow,hospitalization time and cost,and postoperative complications between two groups were compared.Results:The postoperative drainage flow and hospitalization time between two groups were not statistically significant(P>0.05).The operative time,intraoperative blood loss and hospitalization cost in endoscopy group were longer,less and higher than those in conventional group,respectively(P<0.01).Three cases with hoarseness in endoscopy group were found after operation,who recovered after two months of operation.Conclusions:The endoscopic thyroidectomy by breast approach is a safe and minimally invasive method,which is worth popularizing in specific populations.
Objective:To compare the clinical effects of the endoscopic thyroidectomy by breast approach and conventional thyroidectomy in the treatment of benign thyroid disease.Methods:Among 60 patients with benign thyroid disease,20 cases were treated with the endoscopic thyroidectomy by breast approach(endoscopy group),35 cases were treated with conventional thyroidectomy(convention group).The operative time,intraoperative blood loss,postoperative drainage flow,hospitalization time and cost,and postoperative complications between two groups were compared.Results:The postoperative drainage flow and hospitalization time between two groups were not statistically significant(P>0.05).The operative time,intraoperative blood loss and hospitalization cost in endoscopy group were longer,less and higher than those in conventional group,respectively(P<0.01).Three cases with hoarseness in endoscopy group were found after operation,who recovered after two months of operation.Conclusions:The endoscopic thyroidectomy by breast approach is a safe and minimally invasive method,which is worth popularizing in specific populations.
2015, 40(8): 1008-1011.
doi: 10.13898/j.cnki.issn.1000-2200.2015.08.007
Abstract:
Objective:To observe the clinical effects of the application of comprehensive digestive tract poison removal in patients with severe organophosphorus pesticide poisoning(AOPP).Methods:Fifty-six severe AOPP patients were randomly divided into the control group and observation group.The control group and observation group were treated with the conventional gastric lavage,atropine,anti-infection and oxygen therapy,and comprehensive digestive tract poison removal based on the control group,respectively.The general condition,serological indexes and outcome between two groups were compared.Results:The hospitalization time,hospitalization cost,cleaning intestinal time,atropine dosage,pralidoxime chloride dosage,atropinization time and cholinesterase recovery time in observation group were significantly less than those in control group(P<0.01).After treatment,the levels of the white blood cells,creatine kinase,lactate dehydrogenase,aspartate transaminase,serum resistin and visfatin in two groups decreased significantly(P<0.01),and the decreasing degree of whose in observation group were significantly higher than those in control group(P<0.01).The mortality and incidence of severe complications in observation group were significantly lower than those in control group(P<0.01).Conclusions:The comprehensive digestive tract poison removal can clean poison,recover cholinesterase level,improve cure rate and reduce complications,which is worthy of clinical use during the treatment of severe AOPP.
Objective:To observe the clinical effects of the application of comprehensive digestive tract poison removal in patients with severe organophosphorus pesticide poisoning(AOPP).Methods:Fifty-six severe AOPP patients were randomly divided into the control group and observation group.The control group and observation group were treated with the conventional gastric lavage,atropine,anti-infection and oxygen therapy,and comprehensive digestive tract poison removal based on the control group,respectively.The general condition,serological indexes and outcome between two groups were compared.Results:The hospitalization time,hospitalization cost,cleaning intestinal time,atropine dosage,pralidoxime chloride dosage,atropinization time and cholinesterase recovery time in observation group were significantly less than those in control group(P<0.01).After treatment,the levels of the white blood cells,creatine kinase,lactate dehydrogenase,aspartate transaminase,serum resistin and visfatin in two groups decreased significantly(P<0.01),and the decreasing degree of whose in observation group were significantly higher than those in control group(P<0.01).The mortality and incidence of severe complications in observation group were significantly lower than those in control group(P<0.01).Conclusions:The comprehensive digestive tract poison removal can clean poison,recover cholinesterase level,improve cure rate and reduce complications,which is worthy of clinical use during the treatment of severe AOPP.
2015, 40(8): 1011-1013.
doi: 10.13898/j.cnki.issn.1000-2200.2015.08.008
Abstract:
Objective:To observe the effects and safety of oxaliplatin and mannitol injection combined with raltitrexed in the treatment of advanced gastric cancer.Methods:Forty-two elderly patients with advanced gastric cancer were randomly divided into the treatment group and control group(21 cases each group).The treatment group were treated with 130 mg/m2 of oxaliplatin and mannitol injection combined with 3 mg/m2 of raltitrexed by intravenous drip,the control group were treated with 100 mg/m2 of cisplatin injection by intravenous drip combined with 1 000 mg/m2 of capacitabin by oral,twice a day.The clinical effects and adverse reactions between 2 groups after two courses(21 days each course) were compared.Results:The total effect rates in treatment group and control group were 52.4% and 42.9%,respectively,the difference of which was not statistically significant(P>0.05).The incidences of grade Ⅰ-Ⅱ and Ⅲ-Ⅳ adverse reactions in treatment group and control group were 61.9% & 38.1% and 28.6% & 71.4%,respectively,the differences of whose were statistically significant(P<0.05).Conclusions:The treatment of advanced gastric cancer in elderly with oxaliplatin and mannitol injection combined with raltitrexed is less adverse reactions,and easy to tolerate.
Objective:To observe the effects and safety of oxaliplatin and mannitol injection combined with raltitrexed in the treatment of advanced gastric cancer.Methods:Forty-two elderly patients with advanced gastric cancer were randomly divided into the treatment group and control group(21 cases each group).The treatment group were treated with 130 mg/m2 of oxaliplatin and mannitol injection combined with 3 mg/m2 of raltitrexed by intravenous drip,the control group were treated with 100 mg/m2 of cisplatin injection by intravenous drip combined with 1 000 mg/m2 of capacitabin by oral,twice a day.The clinical effects and adverse reactions between 2 groups after two courses(21 days each course) were compared.Results:The total effect rates in treatment group and control group were 52.4% and 42.9%,respectively,the difference of which was not statistically significant(P>0.05).The incidences of grade Ⅰ-Ⅱ and Ⅲ-Ⅳ adverse reactions in treatment group and control group were 61.9% & 38.1% and 28.6% & 71.4%,respectively,the differences of whose were statistically significant(P<0.05).Conclusions:The treatment of advanced gastric cancer in elderly with oxaliplatin and mannitol injection combined with raltitrexed is less adverse reactions,and easy to tolerate.
2015, 40(8): 1014-1015,1019.
doi: 10.13898/j.cnki.issn.1000-2200.2015.08.009
Abstract:
Objective:To explore the related factors of oligohydramnios and its effect on the peninatal infant.Methods:The clinical data of 122 full-term pregnancy cases with oligohydramnios were retrospectively analyzed.The 122 full-term pregnancy women with normal amniotic fluid volume were set as the control group.Results:With the increasing of gestational weeks,the incidence of oligohydramnios in full-term pregnancy cases increased(P<0.01).The pregnancy complications,fetal distress,neonatal asphyxia,late deceleration at non-stress test,variable deceleration,amniotic fluid pullution and aspiration pneumonia in oligohydramnios group were higher than those in control group(P<0.05 to P<0.01).The cesarean section rate in oligohydramnios group was higher than that in normal group(P<0.01).Conclusions:Oligohydramnios is an important signal of fetal risk,and upon diagnosis,the cesarean section should be implemented.
Objective:To explore the related factors of oligohydramnios and its effect on the peninatal infant.Methods:The clinical data of 122 full-term pregnancy cases with oligohydramnios were retrospectively analyzed.The 122 full-term pregnancy women with normal amniotic fluid volume were set as the control group.Results:With the increasing of gestational weeks,the incidence of oligohydramnios in full-term pregnancy cases increased(P<0.01).The pregnancy complications,fetal distress,neonatal asphyxia,late deceleration at non-stress test,variable deceleration,amniotic fluid pullution and aspiration pneumonia in oligohydramnios group were higher than those in control group(P<0.05 to P<0.01).The cesarean section rate in oligohydramnios group was higher than that in normal group(P<0.01).Conclusions:Oligohydramnios is an important signal of fetal risk,and upon diagnosis,the cesarean section should be implemented.
2015, 40(8): 1016-1019.
doi: 10.13898/j.cnki.issn.1000-2200.2015.08.010
Abstract:
Objective:To investigate the relationship between the inspiratory capacity(IC) and Borg score,hospitalization time and cost in patients with acute exacerbation of chronic obstructive pulmonary disease(AECOPD),and provide the basis in evaluating the clinical effects.Methods:The 84 AECOPD patients with improvement rate ≥12% or increasing 200 ml of △IC,and <12% or increasing <200 ml were divided into the control Ⅰ group and observation group.The patients treated with continual treatment using the original scheme or combined with 18 μg/d of tiotropium were divided into the control Ⅱ group and Ⅲ group,respectively.The pulmonary ventilation function and lung capacity,Borg score,blood gas analysis,hospitalization time and cost in all patents were analyzed after 1 and 3 d of admission and before discharge.Results:After 3 d of admission and before discharge,IC in 3 groups were than that in the first day after adnission(P<0.05 to P<0.01),and the IC in Ⅰ group was significantly higher than that in the third day after admission(P<0.01).The differences of the Borg score,FEV1 and IC/TLC in 3 groups,and the difference of the △FEV1/FVC between Ⅰ and Ⅲ group were statistically significant(P<0.05 to P<0.01).The △PaCO2 in Ⅲ group before discharge was lower than that in the third day after admission(P<0.05).The differences of the △FEV1/FVC in Ⅱ group,FRC and PaO2 in 3 groups and the PaCO2 between Ⅰ and Ⅱ group were not statistical significance(P>0.05).The hospitalization time and cost in Ⅰ,Ⅱ and Ⅲ group were 7 d & 6 800 yuan,11 d & 10 600 yuan and 9 d & 8 700 yuan,respectively.Among the 3 groups in the third day of admission and before discharge,the △ IC in 3 groups were negatively correlated with the △Borg score.hospitalization time and cost(P<0.05),and the △IC/TLC and △FEV1 were not correlated with the △Borg score(P>0.05).Among the 3 groups in the third day of admission and before discharge,the △FRC and △PaO2 were negatively correlated with the hospitalization time(P<0.05),and the △PaCO2 were positively correlated with the hospitalization cost(P<0.05),the △IC/TLC was negatively correlated with the hospitalization cost(P<0.01),the △PaO2 and △PaCO2 were positively correlated with the hospitalization cost(P<0.01),and the △FEV1 and △FEV1/ FVC were not correlated with other factors(P>0.05).Conclusions:Inspiratory capacity can evaluate the patients with acute chronic obstructive pulmonary disease before and after treatment,which is conducive to judge the clinical effects and formulate the treatment plan.
Objective:To investigate the relationship between the inspiratory capacity(IC) and Borg score,hospitalization time and cost in patients with acute exacerbation of chronic obstructive pulmonary disease(AECOPD),and provide the basis in evaluating the clinical effects.Methods:The 84 AECOPD patients with improvement rate ≥12% or increasing 200 ml of △IC,and <12% or increasing <200 ml were divided into the control Ⅰ group and observation group.The patients treated with continual treatment using the original scheme or combined with 18 μg/d of tiotropium were divided into the control Ⅱ group and Ⅲ group,respectively.The pulmonary ventilation function and lung capacity,Borg score,blood gas analysis,hospitalization time and cost in all patents were analyzed after 1 and 3 d of admission and before discharge.Results:After 3 d of admission and before discharge,IC in 3 groups were than that in the first day after adnission(P<0.05 to P<0.01),and the IC in Ⅰ group was significantly higher than that in the third day after admission(P<0.01).The differences of the Borg score,FEV1 and IC/TLC in 3 groups,and the difference of the △FEV1/FVC between Ⅰ and Ⅲ group were statistically significant(P<0.05 to P<0.01).The △PaCO2 in Ⅲ group before discharge was lower than that in the third day after admission(P<0.05).The differences of the △FEV1/FVC in Ⅱ group,FRC and PaO2 in 3 groups and the PaCO2 between Ⅰ and Ⅱ group were not statistical significance(P>0.05).The hospitalization time and cost in Ⅰ,Ⅱ and Ⅲ group were 7 d & 6 800 yuan,11 d & 10 600 yuan and 9 d & 8 700 yuan,respectively.Among the 3 groups in the third day of admission and before discharge,the △ IC in 3 groups were negatively correlated with the △Borg score.hospitalization time and cost(P<0.05),and the △IC/TLC and △FEV1 were not correlated with the △Borg score(P>0.05).Among the 3 groups in the third day of admission and before discharge,the △FRC and △PaO2 were negatively correlated with the hospitalization time(P<0.05),and the △PaCO2 were positively correlated with the hospitalization cost(P<0.05),the △IC/TLC was negatively correlated with the hospitalization cost(P<0.01),the △PaO2 and △PaCO2 were positively correlated with the hospitalization cost(P<0.01),and the △FEV1 and △FEV1/ FVC were not correlated with other factors(P>0.05).Conclusions:Inspiratory capacity can evaluate the patients with acute chronic obstructive pulmonary disease before and after treatment,which is conducive to judge the clinical effects and formulate the treatment plan.
2015, 40(8): 1020-1022.
doi: 10.13898/j.cnki.issn.1000-2200.2015.08.011
Abstract:
Objective:To investigate the clinical condition of pulmonary infection caused by severe head trauma infensive care unit,and observe its clinical manifestations and drug effects.Methods:The clinical diagnosis and treatment data of 110 cases with pulmonary infection caused by severe head trauma were retrospectively analyzed.Results:The incidence of pulmonary infection caused by severe head trauma was high.Eighty-eight strains of gram-negative bacteria(73.3%),26 strains of gram-positive bacteria(21.7%) and 6 strains of fungi(5.0%) were found.The sensitivities of imipenem and vancomycin were the highest.All patients were alleviated after treatment.Conclusions:The gram-negative bacteria in pulmonary infection caused by severe head trauma infensive care unit is the major pathogenic bacteria.The patient is multiple drug resistance,the use of antibiotics should be strictly control.
Objective:To investigate the clinical condition of pulmonary infection caused by severe head trauma infensive care unit,and observe its clinical manifestations and drug effects.Methods:The clinical diagnosis and treatment data of 110 cases with pulmonary infection caused by severe head trauma were retrospectively analyzed.Results:The incidence of pulmonary infection caused by severe head trauma was high.Eighty-eight strains of gram-negative bacteria(73.3%),26 strains of gram-positive bacteria(21.7%) and 6 strains of fungi(5.0%) were found.The sensitivities of imipenem and vancomycin were the highest.All patients were alleviated after treatment.Conclusions:The gram-negative bacteria in pulmonary infection caused by severe head trauma infensive care unit is the major pathogenic bacteria.The patient is multiple drug resistance,the use of antibiotics should be strictly control.
2015, 40(8): 1023-1025.
doi: 10.13898/j.cnki.issn.1000-2200.2015.08.012
Abstract:
Objective:To evaluate the sedative effects and safety of the compound anesthesia of midazolam-fentanyl during the detection of electronic bronchoscopy.Methods:One hundred and four patients detected by the electronic bronchoscopy were randomly divided into the midazolam-fentanyl group(A group) and conventional group(B group)(52 cases each group).The 2% lidocaine spraying nasal and throat surface for 4 times,and 0.9% saline infusion(dripping speed of 1.5 ml/min) were used in all patients before check.Before 5 min of check,the 3.0 mg midazolam combined with 50 μg fentanyl and 5 ml 0.9% saline infusion were slowly injected into A group and B group,respectively.Two groups were detected after 2 min of using drug.The systolic blood pressure(SBP),mean arterial pressure(MAP),breathing(RR),heart rate(HR) and blood oxygen saturation(SpO2) before using drug(T0) and after 2 min(T1),5 min(T2),10 min(T3),15 min(T4) and 30 min(T5) of medication in two groups were recorded,and the cough,nausea,vomiting,breath control,interrupt checking and bad memories in two groups were observed.Results:Among A group,the SBP at T1 to T3,and MAP & HR at T1 to T4 were lower than those at T0(P<0.05 to P<0.01),and the differences between the SBP at T5,MAP and HR at T1 to T4 and RR at T1 to T5 and those at T0 were not statistical significance(P>0.05).The MAP and HR at T1 to T4 in B group were higher than those at T0 in B group and A group(P<0.05 to P<0.01).Compared with T0,the SpO2 in two groups decreased(P<0.01),but the SpO2 at T1 to T4 in B group were lower than those in A group(P<0.01).The incidence rates of choke,cough,nausea,vomiting,bad breath and memory in B group were higher than those in A group(P<0.05 to P<0.01),The check in 8 cases of B group were interrupted by the excessive stimulus.Conclusions:The compound anesthesia of midazolam-fentanyl is an ideal clinical sedation drug in patients detected by the electronic bronchoscopy.
Objective:To evaluate the sedative effects and safety of the compound anesthesia of midazolam-fentanyl during the detection of electronic bronchoscopy.Methods:One hundred and four patients detected by the electronic bronchoscopy were randomly divided into the midazolam-fentanyl group(A group) and conventional group(B group)(52 cases each group).The 2% lidocaine spraying nasal and throat surface for 4 times,and 0.9% saline infusion(dripping speed of 1.5 ml/min) were used in all patients before check.Before 5 min of check,the 3.0 mg midazolam combined with 50 μg fentanyl and 5 ml 0.9% saline infusion were slowly injected into A group and B group,respectively.Two groups were detected after 2 min of using drug.The systolic blood pressure(SBP),mean arterial pressure(MAP),breathing(RR),heart rate(HR) and blood oxygen saturation(SpO2) before using drug(T0) and after 2 min(T1),5 min(T2),10 min(T3),15 min(T4) and 30 min(T5) of medication in two groups were recorded,and the cough,nausea,vomiting,breath control,interrupt checking and bad memories in two groups were observed.Results:Among A group,the SBP at T1 to T3,and MAP & HR at T1 to T4 were lower than those at T0(P<0.05 to P<0.01),and the differences between the SBP at T5,MAP and HR at T1 to T4 and RR at T1 to T5 and those at T0 were not statistical significance(P>0.05).The MAP and HR at T1 to T4 in B group were higher than those at T0 in B group and A group(P<0.05 to P<0.01).Compared with T0,the SpO2 in two groups decreased(P<0.01),but the SpO2 at T1 to T4 in B group were lower than those in A group(P<0.01).The incidence rates of choke,cough,nausea,vomiting,bad breath and memory in B group were higher than those in A group(P<0.05 to P<0.01),The check in 8 cases of B group were interrupted by the excessive stimulus.Conclusions:The compound anesthesia of midazolam-fentanyl is an ideal clinical sedation drug in patients detected by the electronic bronchoscopy.
2015, 40(8): 1026-1028.
doi: 10.13898/j.cnki.issn.1000-2200.2015.08.013
Abstract:
Objective:To evaluate the clinical value and safety of the right internal jugular vein puncture and catherization guided by ultrasound diagnostic location.Methods:Two hundred and four patients scheduled by operation with the right internal jugular vein puncture and catherization guided by ultrasound diagnostic location were divided into the conventional surface mark positioning(group A),long axial group(group B),long-short axial group(group C) and short axial group(group D) according to the random number table(51 cases each group).Puncture conditions in four groups were recorded.Results:The differences of the puncture success rates between four groups were statistically significant(P<0.01),the differences of the puncture success rates between A,B and C groups were not statistical significance(P>0.05).The puncture condition in A group was worse than that in B,C and D group,the differences of which were statistically significant(P<0.05 to P<0.01).The differences of test times and number of puncture site between B,C and D group were not statistically significant(P>0.05).The differences of adjusting direction times,puncture time and technical difficulty score between B,C and D group were statistical significance(P<0.05 to P<0.01),but in B and C groups,the difference of which was not statistically significant(P>0.05).The incidences of complications in group B and C were lower than that in group A(P<0.05),while the difference of which between A and D group was not statistically significant(P>0.05).Conclusions:The right internal jugular vein puncture and catherization guided by ultrasound diagnostic location is safe,high successful rate.The long-short axial puncture method has the advantages of both long and short axis,which can improve the successful rate,efficacy and safety,and is worthy of clinical promotion.
Objective:To evaluate the clinical value and safety of the right internal jugular vein puncture and catherization guided by ultrasound diagnostic location.Methods:Two hundred and four patients scheduled by operation with the right internal jugular vein puncture and catherization guided by ultrasound diagnostic location were divided into the conventional surface mark positioning(group A),long axial group(group B),long-short axial group(group C) and short axial group(group D) according to the random number table(51 cases each group).Puncture conditions in four groups were recorded.Results:The differences of the puncture success rates between four groups were statistically significant(P<0.01),the differences of the puncture success rates between A,B and C groups were not statistical significance(P>0.05).The puncture condition in A group was worse than that in B,C and D group,the differences of which were statistically significant(P<0.05 to P<0.01).The differences of test times and number of puncture site between B,C and D group were not statistically significant(P>0.05).The differences of adjusting direction times,puncture time and technical difficulty score between B,C and D group were statistical significance(P<0.05 to P<0.01),but in B and C groups,the difference of which was not statistically significant(P>0.05).The incidences of complications in group B and C were lower than that in group A(P<0.05),while the difference of which between A and D group was not statistically significant(P>0.05).Conclusions:The right internal jugular vein puncture and catherization guided by ultrasound diagnostic location is safe,high successful rate.The long-short axial puncture method has the advantages of both long and short axis,which can improve the successful rate,efficacy and safety,and is worthy of clinical promotion.
2015, 40(8): 1029-1031,1035.
doi: 10.13898/j.cnki.issn.1000-2200.2015.08.014
Abstract:
Objective:To compare the value between the 128-slice spiral CT coronary angiography and selective coronary arteriography in the diagnosis of coronary heart disease.Methods:Three hundred and fifty-two vessels(4 vessels each patients in 88 patients),which included left anterior descending artery,left circumflex branch,left main and right coronary artery,were detected using 128-slice spiral CT coronary angiography and selective coronary arteriography,respectively.The coronary image character was observed.The sensitivity,specificity,positive and negative predictive rates of CT coronary angiography in two kinds of detection methods were analyzed according to the golden standard of coronary angiography.Results:The difference of the coronary artery stenosis diagnosis between two kinds of detection methods was not statistically significant(P>0.05).The sensitivity,specificity,positive and negative predictive rates of CT coronary angiography in two kinds of detection methods were 97.24%,92.40%,93.12% and 96.93%,respectively.The difference of the coronary artery stenosis staging between two kinds of detection methods was not statistically significant(P<0.01).Conclusions:The detection result of 128-slice spiral CT coronary angiography is similar to the selective coronary arteriographye,which is convenient,noninvasive,low radiation,and can be widely used in clinical.
Objective:To compare the value between the 128-slice spiral CT coronary angiography and selective coronary arteriography in the diagnosis of coronary heart disease.Methods:Three hundred and fifty-two vessels(4 vessels each patients in 88 patients),which included left anterior descending artery,left circumflex branch,left main and right coronary artery,were detected using 128-slice spiral CT coronary angiography and selective coronary arteriography,respectively.The coronary image character was observed.The sensitivity,specificity,positive and negative predictive rates of CT coronary angiography in two kinds of detection methods were analyzed according to the golden standard of coronary angiography.Results:The difference of the coronary artery stenosis diagnosis between two kinds of detection methods was not statistically significant(P>0.05).The sensitivity,specificity,positive and negative predictive rates of CT coronary angiography in two kinds of detection methods were 97.24%,92.40%,93.12% and 96.93%,respectively.The difference of the coronary artery stenosis staging between two kinds of detection methods was not statistically significant(P<0.01).Conclusions:The detection result of 128-slice spiral CT coronary angiography is similar to the selective coronary arteriographye,which is convenient,noninvasive,low radiation,and can be widely used in clinical.
2015, 40(8): 1032-1035.
doi: 10.13898/j.cnki.issn.1000-2200.2015.08.015
Abstract:
Objective:To compare the effects between primary suture and intraoperative indwelling T tube in laparoscopic common bill duct exploration(LCDBDE).Methods:One hundred and eighty-six patients treated with LCBDE were randomly divided into the primary suture group(98 cases) and intraoperative indwelling T tube group(88 cases).The operation time,bleeding volume,postoperative hospitalization time,bile loss,hospitalization expense,anal exhaust time,the use time of antibiotics,amount of infusion,transfusion time,gastric function recovery time,postoperative ambulation time,adverse reactions and quality of life between two groups were compared.Results:The postoperative bleeding volume,hospitalization time,bile loss,hospitalization expense,anal exhaust time,the use time of antibiotics,amount of infusion,transfusion time,gastric function recovery time and postoperative ambulation time in the primary suture group were less than those in intraoperative indwelling T tube group(P<0.05 to P<0.01).The total incidence rates of adverse reaction in primary suture group and intraoperative indwelling T tube group were 6.82% and 7.14%,respectively,the difference of which was not statistically significant(P>0.05).According to the evaluation standard of the SF-36 life quality,the dimensions and total score of quality of life in primary suture group were significantly higher than those in intraoperative indwelling T tube group(P<0.01).Conclusions:Compared with the intraoperative indwelling T tube,the effects of primary suture in LCBDE is good,which should be promoted and application.
Objective:To compare the effects between primary suture and intraoperative indwelling T tube in laparoscopic common bill duct exploration(LCDBDE).Methods:One hundred and eighty-six patients treated with LCBDE were randomly divided into the primary suture group(98 cases) and intraoperative indwelling T tube group(88 cases).The operation time,bleeding volume,postoperative hospitalization time,bile loss,hospitalization expense,anal exhaust time,the use time of antibiotics,amount of infusion,transfusion time,gastric function recovery time,postoperative ambulation time,adverse reactions and quality of life between two groups were compared.Results:The postoperative bleeding volume,hospitalization time,bile loss,hospitalization expense,anal exhaust time,the use time of antibiotics,amount of infusion,transfusion time,gastric function recovery time and postoperative ambulation time in the primary suture group were less than those in intraoperative indwelling T tube group(P<0.05 to P<0.01).The total incidence rates of adverse reaction in primary suture group and intraoperative indwelling T tube group were 6.82% and 7.14%,respectively,the difference of which was not statistically significant(P>0.05).According to the evaluation standard of the SF-36 life quality,the dimensions and total score of quality of life in primary suture group were significantly higher than those in intraoperative indwelling T tube group(P<0.01).Conclusions:Compared with the intraoperative indwelling T tube,the effects of primary suture in LCBDE is good,which should be promoted and application.
2015, 40(8): 1036-1039.
doi: 10.13898/j.cnki.issn.1000-2200.2015.08.016
Abstract:
Objective:To explore the clinical effects of the artificial humeral head replacement in the treatment of complex proximal humeral fractures.Methods:Fourteen elderly patients with proximal comminuted fracture of the humerus were treated with humeral head replacement.The distance between the lowest point of great tuberosity of humerus and highest point of the humeral head in unaffected side before operation was measured.Reasonable controlling the prosthesis depth,paying attention to the angle,reducing large and small tuberosity and repairing the rotator cuff were implemented before treatment,and the personalized plan of rehabilitation exercise were formulated after operation.Results:Fourteen cases were followed up for 3 to 70 months,all patients could do the ordinary daily action.Excellent in 5 cases,good in 7 cases and moderate in 2 cases were identified according to Neer scores,the rate of excellent-to-good was 85.7%.Conclusions:Strict controlling the indications,good prosthesis installing,repairing the rotator cuff,planned rehabilitation exercises and humeral head replacement is a good method in treating complex proximal humerus fractures in elderly.
Objective:To explore the clinical effects of the artificial humeral head replacement in the treatment of complex proximal humeral fractures.Methods:Fourteen elderly patients with proximal comminuted fracture of the humerus were treated with humeral head replacement.The distance between the lowest point of great tuberosity of humerus and highest point of the humeral head in unaffected side before operation was measured.Reasonable controlling the prosthesis depth,paying attention to the angle,reducing large and small tuberosity and repairing the rotator cuff were implemented before treatment,and the personalized plan of rehabilitation exercise were formulated after operation.Results:Fourteen cases were followed up for 3 to 70 months,all patients could do the ordinary daily action.Excellent in 5 cases,good in 7 cases and moderate in 2 cases were identified according to Neer scores,the rate of excellent-to-good was 85.7%.Conclusions:Strict controlling the indications,good prosthesis installing,repairing the rotator cuff,planned rehabilitation exercises and humeral head replacement is a good method in treating complex proximal humerus fractures in elderly.
2015, 40(8): 1039-1041.
doi: 10.13898/j.cnki.issn.1000-2200.2015.08.017
Abstract:
Objective:To analyze the influence factors of the delivery of macrosomia in pregnant women with gestational diabitets mellitus(GDM).Methods:The clinical data,which included the age,height,pre-pregnancy body mass index,increase of body mass,family history of diabetes,abnormal pregnancy history,neonatal sex,treatment programmes of blood sugar,blood sugar control and delivery of macrosomiain 371 GDM pregnant women with more than 37 weeks LSA were retrospectively analyzed.The influence factors of the incidence of macrosomia in pregnant women with GDM were analyzed using multi-factor logistic regression analysis.Results:The height and body mass of pregnant women and male newborns in macrosomia group were higher than those in nonmacrosomia group(P<0.01 to P<0.05),the good rate of blood sugar control in macrosomia group was significantly lower than that in nonmacrosomia group(P<0.01).The analysis showed that the difference of body mass index between before and after pregnancy and blood sugar control were the independent influence factors of the delivery of macrosomia in pregnant women with GDM(P<0.05).Conclusions:The effective controlling the excessive growth of body mass and maintaining the good blood sugar level in pregnant women with GDM can reduce the incidence of the delivery of macrosomia.
Objective:To analyze the influence factors of the delivery of macrosomia in pregnant women with gestational diabitets mellitus(GDM).Methods:The clinical data,which included the age,height,pre-pregnancy body mass index,increase of body mass,family history of diabetes,abnormal pregnancy history,neonatal sex,treatment programmes of blood sugar,blood sugar control and delivery of macrosomiain 371 GDM pregnant women with more than 37 weeks LSA were retrospectively analyzed.The influence factors of the incidence of macrosomia in pregnant women with GDM were analyzed using multi-factor logistic regression analysis.Results:The height and body mass of pregnant women and male newborns in macrosomia group were higher than those in nonmacrosomia group(P<0.01 to P<0.05),the good rate of blood sugar control in macrosomia group was significantly lower than that in nonmacrosomia group(P<0.01).The analysis showed that the difference of body mass index between before and after pregnancy and blood sugar control were the independent influence factors of the delivery of macrosomia in pregnant women with GDM(P<0.05).Conclusions:The effective controlling the excessive growth of body mass and maintaining the good blood sugar level in pregnant women with GDM can reduce the incidence of the delivery of macrosomia.
2015, 40(8): 1042-1043.
doi: 10.13898/j.cnki.issn.1000-2200.2015.08.018
Abstract:
Objective:To compare the effects of enteral nutrition(EN) support with parenteral nutrition(PN) support on the early clinical recovery of patients after gastric cancer radical surgery.Methods:Forty patients with gastric cancer were randomly divided into the PN group and EN group.The PN group was treated with total PN support and EN support at 2 days after operation,and the EN group then gradual converting for total EN support,respectively.The early clinical recovery effects between two groups were compared.Results:The postoperative anal exhaust time and average hospital stay in EN group were shorter than those in PN group(P<0.01).The incidence of postoperative complications in EN group was lower than that in PN group(P<0.05).Conclusions:The early treatment of postoperative gastric cancer with enteral nutrition support can improve the nutritive condition,promote intestinal peristalsis recovery and reduce complications of patients,which is an ideal way of nutritional support after gastric cancer radical surgery.
Objective:To compare the effects of enteral nutrition(EN) support with parenteral nutrition(PN) support on the early clinical recovery of patients after gastric cancer radical surgery.Methods:Forty patients with gastric cancer were randomly divided into the PN group and EN group.The PN group was treated with total PN support and EN support at 2 days after operation,and the EN group then gradual converting for total EN support,respectively.The early clinical recovery effects between two groups were compared.Results:The postoperative anal exhaust time and average hospital stay in EN group were shorter than those in PN group(P<0.01).The incidence of postoperative complications in EN group was lower than that in PN group(P<0.05).Conclusions:The early treatment of postoperative gastric cancer with enteral nutrition support can improve the nutritive condition,promote intestinal peristalsis recovery and reduce complications of patients,which is an ideal way of nutritional support after gastric cancer radical surgery.
2015, 40(8): 1044-1046.
doi: 10.13898/j.cnki.issn.1000-2200.2015.08.019
Abstract:
Objective:To evaluate the efficacy and safety of tension free obturator tape technique(TOT) in the treatment female stress urinary incontinence(SUI).Methods:Thirty-two patients with SUI were treated with TOT.The effect of surgery were follow-up at postoperative 6 and 24 months.Results:The operative time,blood loss,postoperative hospital stay and surgical success rate in 32 cases were 28-46 min,22-56 ml,was 4-7 d and 96.9%,respectively.No serious complication was found.The differences of the surgery efficacy,score of quality of life,residual urine and maximum urinary flow rate between all cases were not statistically different at postoperative 6 and 24 months(P>0.05).Conclusions:The treatment of female SUI with TOT is safe,effective,and good long term effect.
Objective:To evaluate the efficacy and safety of tension free obturator tape technique(TOT) in the treatment female stress urinary incontinence(SUI).Methods:Thirty-two patients with SUI were treated with TOT.The effect of surgery were follow-up at postoperative 6 and 24 months.Results:The operative time,blood loss,postoperative hospital stay and surgical success rate in 32 cases were 28-46 min,22-56 ml,was 4-7 d and 96.9%,respectively.No serious complication was found.The differences of the surgery efficacy,score of quality of life,residual urine and maximum urinary flow rate between all cases were not statistically different at postoperative 6 and 24 months(P>0.05).Conclusions:The treatment of female SUI with TOT is safe,effective,and good long term effect.
2015, 40(8): 1046-1048.
doi: 10.13898/j.cnki.issn.1000-2200.2015.08.020
Abstract:
Objective:To compare the clinical value of the detection of exfoliative cytology,serum tumor markers and DNA heteroploid analysis in the diagnosis of malignant pleural effusion and ascite.Methods:The exfoliative cytology,serum tumor markers,DNA heteroploid analysis in 128 patients with peural effusion and ascite were investigated,the sensibilities between three tests were compared.Results:The positive rate of exfoliative cytology testing was 43.75%.The positive rate of exfoliative cytology joint DNA heteroploid analysis was 83.33%,with individual exfoliative cytology,the positive rate was statistically significant(P<0.01). The positive rate of serum tumor markers joint testing was 81.25%, the difference had statistically significant compared with CA125 and AFP single detection(P<0.01).Conclusions:The jiont detection of exfoliative cytology,serum tumor markers and DNA heteroploid analysis can improve the detection rate of malignant pleural effusion and ascite.
Objective:To compare the clinical value of the detection of exfoliative cytology,serum tumor markers and DNA heteroploid analysis in the diagnosis of malignant pleural effusion and ascite.Methods:The exfoliative cytology,serum tumor markers,DNA heteroploid analysis in 128 patients with peural effusion and ascite were investigated,the sensibilities between three tests were compared.Results:The positive rate of exfoliative cytology testing was 43.75%.The positive rate of exfoliative cytology joint DNA heteroploid analysis was 83.33%,with individual exfoliative cytology,the positive rate was statistically significant(P<0.01). The positive rate of serum tumor markers joint testing was 81.25%, the difference had statistically significant compared with CA125 and AFP single detection(P<0.01).Conclusions:The jiont detection of exfoliative cytology,serum tumor markers and DNA heteroploid analysis can improve the detection rate of malignant pleural effusion and ascite.
2015, 40(8): 1049-1050,1054.
doi: 10.13898/j.cnki.issn.1000-2200.2015.08.021
Abstract:
Objective:To observe the curative effects of ultrasound-guided hysteroscopy on myomectomy in uterus membrane.Methods:The operation time,blood loss,postoperative hospital stay,surgery effect,recurrence rate of submucous myoma between 36 cases treated with ultrasound-guided hysteroscopy and 35 cases treated with laparotomy were compared.Results:The operation time,blood loss,hospital stay after surgery in patients treated with hysteroscopy were shorter than those in patients treated with laparotomy(P<0.01),the differences of the surgery effect and recurrence rate between the patients treated with hysteroscopy and laparotomy were not statistically significant(P>0.05).Conclusions:The ultrasound-guided hysteroscopy in myomectomy of uterus membrane is little trauma,quick recovery,security and high feasibility,which is the preferred surgical treatment of uterus membrane myoma.
Objective:To observe the curative effects of ultrasound-guided hysteroscopy on myomectomy in uterus membrane.Methods:The operation time,blood loss,postoperative hospital stay,surgery effect,recurrence rate of submucous myoma between 36 cases treated with ultrasound-guided hysteroscopy and 35 cases treated with laparotomy were compared.Results:The operation time,blood loss,hospital stay after surgery in patients treated with hysteroscopy were shorter than those in patients treated with laparotomy(P<0.01),the differences of the surgery effect and recurrence rate between the patients treated with hysteroscopy and laparotomy were not statistically significant(P>0.05).Conclusions:The ultrasound-guided hysteroscopy in myomectomy of uterus membrane is little trauma,quick recovery,security and high feasibility,which is the preferred surgical treatment of uterus membrane myoma.
2015, 40(8): 1051-1054.
doi: 10.13898/j.cnki.issn.1000-2200.2015.08.022
Abstract:
Objective:To investigate the expressions of matrix metalloproteinases-2,7 and 9(MMP-2,MMP-7 and MMP-9) and extracellular matrix metalloproteinase inducer(EMMPRIN) and their roles in the development process of colorectal carcinoma.Methods:The protein expressions of MMP-2,MMP-7,MMP-9 and EMMPRIN in 100 colorectal carcinoma tissue samples were detected by immunohistochemical method.Results:The differences of the expressions rates of MMP-2,MMP-7,MMP-9 and EMMPRIN in colorectal carcinoma tissue samples with different invasion depth,Dukes stage and lymph node metastasis were statistically significant(P<0.05).The expressions between EMMPRIN and MMP-2,MMP-7 and MMP-9 in colorectal carcinoma tissue were significant positive correlation,respectively(P<0.01).Conclusions:The expressions of MMP-2,MMP-7,MMP-9 and EMMPRIN have synergetic effects in the development of colorectal carcinoma.
Objective:To investigate the expressions of matrix metalloproteinases-2,7 and 9(MMP-2,MMP-7 and MMP-9) and extracellular matrix metalloproteinase inducer(EMMPRIN) and their roles in the development process of colorectal carcinoma.Methods:The protein expressions of MMP-2,MMP-7,MMP-9 and EMMPRIN in 100 colorectal carcinoma tissue samples were detected by immunohistochemical method.Results:The differences of the expressions rates of MMP-2,MMP-7,MMP-9 and EMMPRIN in colorectal carcinoma tissue samples with different invasion depth,Dukes stage and lymph node metastasis were statistically significant(P<0.05).The expressions between EMMPRIN and MMP-2,MMP-7 and MMP-9 in colorectal carcinoma tissue were significant positive correlation,respectively(P<0.01).Conclusions:The expressions of MMP-2,MMP-7,MMP-9 and EMMPRIN have synergetic effects in the development of colorectal carcinoma.
2015, 40(8): 1055-1056,1059.
doi: 10.13898/j.cnki.issn.1000-2200.2015.08.023
Abstract:
Objective:To investigate the effects of body mass index(BMI) before pregnancy and different periods of pregnancy on neonatal body mass.Methods:The data of the complete prenatal records of 2 260 singleton pregnant women with normal delivery were retrospectively analyzed.Results:The incidence rates of macrosomia in obese and overweight groups were significantly higher than that in low and normal weight groups during pre-pregnancy and early pregnancy(P<0.01).During the second and third trimester,the incidence rate of macrosomia in obese groups was the highest,and the incidence rate of macrosomia in low and normal weight groups was the lowest,the difference of which was not statistically significant(P<0.01).Conclusions:The BMI before pregnancy and different periods of pregnancy is positive correlation with mocrosomia.Strict monitoring the pregnant BMI and controlling weight growth in the normal range are beneficial to prevent the occurrence of macrosomia,and the health of mothers and children.
Objective:To investigate the effects of body mass index(BMI) before pregnancy and different periods of pregnancy on neonatal body mass.Methods:The data of the complete prenatal records of 2 260 singleton pregnant women with normal delivery were retrospectively analyzed.Results:The incidence rates of macrosomia in obese and overweight groups were significantly higher than that in low and normal weight groups during pre-pregnancy and early pregnancy(P<0.01).During the second and third trimester,the incidence rate of macrosomia in obese groups was the highest,and the incidence rate of macrosomia in low and normal weight groups was the lowest,the difference of which was not statistically significant(P<0.01).Conclusions:The BMI before pregnancy and different periods of pregnancy is positive correlation with mocrosomia.Strict monitoring the pregnant BMI and controlling weight growth in the normal range are beneficial to prevent the occurrence of macrosomia,and the health of mothers and children.
2015, 40(8): 1057-1059.
doi: 10.13898/j.cnki.issn.1000-2200.2015.08.024
Abstract:
Objective:To observe the changes of Narcotrend index(NTI) during sevoflurane inhalation anesthesia,analyze the clinical significance of monitoring the depth of anesthesia using NTI,and explore the accuracy,sensitivity and stability.Methods:Ninety patients(ASA grade Ⅰ to Ⅱ) scheduled by abdominal surgery under general anesthesia through endotracheal intubation were selected.The vital signs and NTI value in the patients were monitored,all cases inhaled sevoflurane.The endotracheal intubation in the patients were implemented following by intravenous injection of sufentanyl and cisatracurium after the consciousness of patients disappeared.The levels of NTI,mean aortic pressure(MAP),heart rate(HR) and blood glucose(Glu) in all cases were recorded at the beginning of induction(T0),before incubation(T1),incubation(T2),after 3 min of intubation(T3),after cutting skin(T4),opening abdomen(T5),stopping sevoflurane(T6),before excubation(T7) and after 5 min of excubation(T8).Results:The levels of NTI,MAP and HR dropped gradually with the time prolonging of inhaling sevoflurane,which increased after the stimulation of endotracheal intubation,cutting skin,opening abdomen and anesthesia recovery.Compared with T0,the NTI value at T1 and T3 significantly decreased(P<0.01).Compared with T1,the NTI value at T2,T4 and T3 significantly increased(P<0.01).Conclusions:Narcotrend value can accurately monitor the depth of anesthesia during the sevoflurane anesthesia,which can accurately judge the induction period of anesthesia,surgery and anesthesia recovery period to guide the regulation of anesthesia depth.
Objective:To observe the changes of Narcotrend index(NTI) during sevoflurane inhalation anesthesia,analyze the clinical significance of monitoring the depth of anesthesia using NTI,and explore the accuracy,sensitivity and stability.Methods:Ninety patients(ASA grade Ⅰ to Ⅱ) scheduled by abdominal surgery under general anesthesia through endotracheal intubation were selected.The vital signs and NTI value in the patients were monitored,all cases inhaled sevoflurane.The endotracheal intubation in the patients were implemented following by intravenous injection of sufentanyl and cisatracurium after the consciousness of patients disappeared.The levels of NTI,mean aortic pressure(MAP),heart rate(HR) and blood glucose(Glu) in all cases were recorded at the beginning of induction(T0),before incubation(T1),incubation(T2),after 3 min of intubation(T3),after cutting skin(T4),opening abdomen(T5),stopping sevoflurane(T6),before excubation(T7) and after 5 min of excubation(T8).Results:The levels of NTI,MAP and HR dropped gradually with the time prolonging of inhaling sevoflurane,which increased after the stimulation of endotracheal intubation,cutting skin,opening abdomen and anesthesia recovery.Compared with T0,the NTI value at T1 and T3 significantly decreased(P<0.01).Compared with T1,the NTI value at T2,T4 and T3 significantly increased(P<0.01).Conclusions:Narcotrend value can accurately monitor the depth of anesthesia during the sevoflurane anesthesia,which can accurately judge the induction period of anesthesia,surgery and anesthesia recovery period to guide the regulation of anesthesia depth.
2015, 40(8): 1060-1062.
doi: 10.13898/j.cnki.issn.1000-2200.2015.08.025
Abstract:
Objective:To analyze the clinical related factors of non-diabetic fetal macrosomia,and explore its correlation with prepregnancy body mass index(BMI)and weight gain during pregnancy.Methods:Three hundred and twenty-two non-diabetic fetal macrosomia with gestational age from 37 weeks to 42 weeks and 325 normal fetus were divided into the experimental group and control group from 2005 to 2012,respectively.The age,calving parity,height,gestational week,weight gain during pregnancy,prepregnancy and intrapartum BMI,fundal height and abdominal circumference of new mother,and fetal biparietal diameter and femur length between two groups were compared.Results:The weight gain during pregnancy,prepregnancy and intrapartum BMI,fundal height,abdominal circumference,fundal height plus abdominal perimeter and gestational week of new mother,and the fetal biparietal diameter,femur length,fetal biparietal diameter plus femur length and height in experimental group were more than those in control group(P<0.01).The correlation analysis showed that the fetal biparietal diameter,fetal biparietal diameter plus femur length and weight gain during pregnancy were positive correlation with macrosomia(P<0.05 to P<0.01).Conclusions:The incidence of non-diabetic fetal macrosomia is closely related to the excessively gestational weight gain.The measure of fetal biparietal diameter plus femur length in excessive maternal weight gain during pregnancy can improve the prenatal diagnosis of non-diabetic fetal macrosomia.
Objective:To analyze the clinical related factors of non-diabetic fetal macrosomia,and explore its correlation with prepregnancy body mass index(BMI)and weight gain during pregnancy.Methods:Three hundred and twenty-two non-diabetic fetal macrosomia with gestational age from 37 weeks to 42 weeks and 325 normal fetus were divided into the experimental group and control group from 2005 to 2012,respectively.The age,calving parity,height,gestational week,weight gain during pregnancy,prepregnancy and intrapartum BMI,fundal height and abdominal circumference of new mother,and fetal biparietal diameter and femur length between two groups were compared.Results:The weight gain during pregnancy,prepregnancy and intrapartum BMI,fundal height,abdominal circumference,fundal height plus abdominal perimeter and gestational week of new mother,and the fetal biparietal diameter,femur length,fetal biparietal diameter plus femur length and height in experimental group were more than those in control group(P<0.01).The correlation analysis showed that the fetal biparietal diameter,fetal biparietal diameter plus femur length and weight gain during pregnancy were positive correlation with macrosomia(P<0.05 to P<0.01).Conclusions:The incidence of non-diabetic fetal macrosomia is closely related to the excessively gestational weight gain.The measure of fetal biparietal diameter plus femur length in excessive maternal weight gain during pregnancy can improve the prenatal diagnosis of non-diabetic fetal macrosomia.
2015, 40(8): 1063-1066,1069.
doi: 10.13898/j.cnki.issn.1000-2200.2015.08.026
Abstract:
Objective:To investigate the choice of delivery mode of secondary pregnancy after cesarean section.Methods:Six hundred and fourteen late pregnancy women with cesarean section were set as the observation group,and divided into group A(vaginal birth after cesarean section),group B(who could vaginal delivery,but choosing to cesarean section),group C(secondary cesarean delivery) and group D(third and fourth cesarean delivery).Three hundred and seventy-six late pregnancy women without cesarean section were set as the control group,and divided into group E(vaginal delivery) and group F(first cesarean delivery).The maternal and infant complications,operation time and hospital stay between group A and group B,between group A and group E,and between group C & group D and F group were analyzed.Results:The bleeding volume and time of hospitalization in group A after delivery were significantly less than that in group B(P<0.01).The differences of the rates of puerperal morbidity and neonatal asphyxia between group A and group B were not statistically significant(P>0.05).The differences of the postpartum bleeding volume,puerperal morbidity,time of hospitalization,neonatal asphyxia and rate of vaginal delivery between group A and group E were not statistically significant(P>0.05).The rate of perineal incision in group A was significantly higher than that in group E(P<0.01).The differences of the postpartum bleeding volume,puerperal morbidity,time of hospitalization and neonatal asphyxia between group C,group D and group E were not statistically significant(P>0.05).The operation time and abdominopelvic cavity adhesions rate in group F were significantly less than those in group C(P<0.01).The operation time and abdominopelvic cavity adhesions rate in group C and F were significantly less than those in group D(P<0.01).Conclusions:The vaginal trial production in the pregnant women with repregnance after cesarean section is safe according to the rigorous evaluation and selection,which can short hospitalization days and reduce maternal and infant complications.
Objective:To investigate the choice of delivery mode of secondary pregnancy after cesarean section.Methods:Six hundred and fourteen late pregnancy women with cesarean section were set as the observation group,and divided into group A(vaginal birth after cesarean section),group B(who could vaginal delivery,but choosing to cesarean section),group C(secondary cesarean delivery) and group D(third and fourth cesarean delivery).Three hundred and seventy-six late pregnancy women without cesarean section were set as the control group,and divided into group E(vaginal delivery) and group F(first cesarean delivery).The maternal and infant complications,operation time and hospital stay between group A and group B,between group A and group E,and between group C & group D and F group were analyzed.Results:The bleeding volume and time of hospitalization in group A after delivery were significantly less than that in group B(P<0.01).The differences of the rates of puerperal morbidity and neonatal asphyxia between group A and group B were not statistically significant(P>0.05).The differences of the postpartum bleeding volume,puerperal morbidity,time of hospitalization,neonatal asphyxia and rate of vaginal delivery between group A and group E were not statistically significant(P>0.05).The rate of perineal incision in group A was significantly higher than that in group E(P<0.01).The differences of the postpartum bleeding volume,puerperal morbidity,time of hospitalization and neonatal asphyxia between group C,group D and group E were not statistically significant(P>0.05).The operation time and abdominopelvic cavity adhesions rate in group F were significantly less than those in group C(P<0.01).The operation time and abdominopelvic cavity adhesions rate in group C and F were significantly less than those in group D(P<0.01).Conclusions:The vaginal trial production in the pregnant women with repregnance after cesarean section is safe according to the rigorous evaluation and selection,which can short hospitalization days and reduce maternal and infant complications.
2015, 40(8): 1066-1069.
doi: 10.13898/j.cnki.issn.1000-2200.2015.08.027
Abstract:
Objective:To observe the effects of local injection of ropivacaine combined with patient-controlled intravenous analgesia on the analgesia and early functional exercise after total knee arthroplasty(TKA).Methods:Ninety patients with primary unilateral TKA were randomly divided into the control group and observation group(45 cases each group).The control group and observation group were treated with patient-controlled intravenous analgesia and periarticular local injection of ropivacaine combined with patient-controlled intravenous analgesia,respectively.The knee pain at stationary and moving state between two groups after 6,12,24,48,72 h and 1 week of operation were evaluated and compared using the visual analogue scale(VAS).The range of motion of knee joint in two groups after 24,48,72 h and 1 week of operation were measured.The postoperative dizziness,nausea,vomiting and numbness of the limbs in two groups were observed.Results:The VAS scores in observation group at stationary and moving state after 6,12,24 and 48 h of operation were less than that in control group(P<0.05 to P<0.01).The differences of the VAS scores at stationary and moving state between two groups after 72 h and 1 week of operation were not statistically significant(P>0.05).The early range of motion in observation group was significantly better than that in control group(P<0.01).Conclusions:The periarticular local injection of ropivacaine in the treatment of pain during TKA is a simple,effective and low cost,and which has obviously postoperative analgesic effect,and can contribute to the recovery of knee joint function.
Objective:To observe the effects of local injection of ropivacaine combined with patient-controlled intravenous analgesia on the analgesia and early functional exercise after total knee arthroplasty(TKA).Methods:Ninety patients with primary unilateral TKA were randomly divided into the control group and observation group(45 cases each group).The control group and observation group were treated with patient-controlled intravenous analgesia and periarticular local injection of ropivacaine combined with patient-controlled intravenous analgesia,respectively.The knee pain at stationary and moving state between two groups after 6,12,24,48,72 h and 1 week of operation were evaluated and compared using the visual analogue scale(VAS).The range of motion of knee joint in two groups after 24,48,72 h and 1 week of operation were measured.The postoperative dizziness,nausea,vomiting and numbness of the limbs in two groups were observed.Results:The VAS scores in observation group at stationary and moving state after 6,12,24 and 48 h of operation were less than that in control group(P<0.05 to P<0.01).The differences of the VAS scores at stationary and moving state between two groups after 72 h and 1 week of operation were not statistically significant(P>0.05).The early range of motion in observation group was significantly better than that in control group(P<0.01).Conclusions:The periarticular local injection of ropivacaine in the treatment of pain during TKA is a simple,effective and low cost,and which has obviously postoperative analgesic effect,and can contribute to the recovery of knee joint function.
2015, 40(8): 1077-1080.
doi: 10.13898/j.cnki.issn.1000-2200.2015.08.031
Abstract:
Objective:To compile the emotion management ability scale in medical students,and check its reliability and validity.Methods:The initial entry of questionnaire was compiled according to the theoretical analysis,interview and open questionnaire survey.Four hundred and fifty-eight medical students were investigated for analyzing item and exploratory factors and determining the dimensions and entries of questionnaire.Three hundred medical students were formally evaluated for confirmatory factor and validity analysis,the emotion management ability scale was used as a criterion.Results:The scale was made up of 28 clauses,which included the emotional evaluation,emotional awareness,emotional expression ability and emotion regulation ability.The χ2/df=2.140,RMSEA=0.050,CFI=0.905 and IFI=0.906 fitting index were obtained by analyzing the exploratory factor.The total score was significantly positive related to the emotional intelligence scale(r=0.813,P<0.01).The coefficient of total table was 0.923.the 1/2 reliability of Spearman-Brown was 0.891,and the Cronbacha's α coefficient of four dimensions were 0.864,0.751,0.777 and 0.741,respectively.Conclusions:The emotion management ability scale has a good reliability and validity,which is an effective tool to measure the emotional management ability of medical students.
Objective:To compile the emotion management ability scale in medical students,and check its reliability and validity.Methods:The initial entry of questionnaire was compiled according to the theoretical analysis,interview and open questionnaire survey.Four hundred and fifty-eight medical students were investigated for analyzing item and exploratory factors and determining the dimensions and entries of questionnaire.Three hundred medical students were formally evaluated for confirmatory factor and validity analysis,the emotion management ability scale was used as a criterion.Results:The scale was made up of 28 clauses,which included the emotional evaluation,emotional awareness,emotional expression ability and emotion regulation ability.The χ2/df=2.140,RMSEA=0.050,CFI=0.905 and IFI=0.906 fitting index were obtained by analyzing the exploratory factor.The total score was significantly positive related to the emotional intelligence scale(r=0.813,P<0.01).The coefficient of total table was 0.923.the 1/2 reliability of Spearman-Brown was 0.891,and the Cronbacha's α coefficient of four dimensions were 0.864,0.751,0.777 and 0.741,respectively.Conclusions:The emotion management ability scale has a good reliability and validity,which is an effective tool to measure the emotional management ability of medical students.
2015, 40(8): 1080-1083.
doi: 10.13898/j.cnki.issn.1000-2200.2015.08.032
Abstract:
Objective:To understand the level and characteristics of the difficulties of decision-making career in medical college,and provide a theoretical basis for the better career planning of medical students.Methods:Eight hundred and forty-six students from three medical colleges were investigated using the career decision-making difficulties questionnaire and self-compiled influence factor questionnaire based on open investigation.Results:The difficulty of career decision-making of medical college students is the mild level,which included the emotional discomfort,lack of sufficient access to obtain information and social environment information.The differences of the difficulty score of medical college students in career decision-making in different genders,one-child,different grades and school performance were statistically significant(P<0.05 to P<0.01).Career education,professional satisfaction,professional interest matches and career grasp affected on career decision-making(P<0.05 to P<0.01).Conclusions:The difficulty of career decision-making in medical students is in mild difficulty level,which is affected by different genders,one-child,different grades,school performance,professional satisfaction,professional interest and career grasp.
Objective:To understand the level and characteristics of the difficulties of decision-making career in medical college,and provide a theoretical basis for the better career planning of medical students.Methods:Eight hundred and forty-six students from three medical colleges were investigated using the career decision-making difficulties questionnaire and self-compiled influence factor questionnaire based on open investigation.Results:The difficulty of career decision-making of medical college students is the mild level,which included the emotional discomfort,lack of sufficient access to obtain information and social environment information.The differences of the difficulty score of medical college students in career decision-making in different genders,one-child,different grades and school performance were statistically significant(P<0.05 to P<0.01).Career education,professional satisfaction,professional interest matches and career grasp affected on career decision-making(P<0.05 to P<0.01).Conclusions:The difficulty of career decision-making in medical students is in mild difficulty level,which is affected by different genders,one-child,different grades,school performance,professional satisfaction,professional interest and career grasp.
2015, 40(8): 1084-1086,1090.
doi: 10.13898/j.cnki.issn.1000-2200.2015.08.033
Abstract:
Objective:To explore the sleep quality and its related factors among the middle school students before entrance examination from Hefei.Methods:One hundred and seventy-seven from the middle school students of Hefei were investigated by the self-designed questionnaire using random cluster sampling method before 2 weeks of entrance examination.The Pittsburgh Sleep Quality Index(PSQI),Self-reporting Inventory(SCL-90) and State-Trait Anxiety Inventory(STAI) of all students were evaluated.Results:Among the students,the detection rate of sleep problems was 31.2%,the mean score of PSQI was(6.23±2.90),and the sleep problems in the private schools were more than those in the public schools(P<0.05 to P<0.01).The total score of PSQI was positively correlated with the students and parental attitude of test defeat,somatization,obsessive-compulsive symptoms,anxiety state and anxiety trait(P<0.05 to P<0.01),and negatively correlated with the favorite school situation(P<0.05).The obsessive-compulsive symptoms(β=0.388),parental attitude of test defeat(β=0.141),students' attitude of test defeat(β=0.144) and somatization(β=0.173) were the influencing factors of the sleep quality of the students.Conclusions:Sleep quality of middle school students is related to multiple factors.The effective measures should be taken to improve the physical and mental health of middle school students.
Objective:To explore the sleep quality and its related factors among the middle school students before entrance examination from Hefei.Methods:One hundred and seventy-seven from the middle school students of Hefei were investigated by the self-designed questionnaire using random cluster sampling method before 2 weeks of entrance examination.The Pittsburgh Sleep Quality Index(PSQI),Self-reporting Inventory(SCL-90) and State-Trait Anxiety Inventory(STAI) of all students were evaluated.Results:Among the students,the detection rate of sleep problems was 31.2%,the mean score of PSQI was(6.23±2.90),and the sleep problems in the private schools were more than those in the public schools(P<0.05 to P<0.01).The total score of PSQI was positively correlated with the students and parental attitude of test defeat,somatization,obsessive-compulsive symptoms,anxiety state and anxiety trait(P<0.05 to P<0.01),and negatively correlated with the favorite school situation(P<0.05).The obsessive-compulsive symptoms(β=0.388),parental attitude of test defeat(β=0.141),students' attitude of test defeat(β=0.144) and somatization(β=0.173) were the influencing factors of the sleep quality of the students.Conclusions:Sleep quality of middle school students is related to multiple factors.The effective measures should be taken to improve the physical and mental health of middle school students.
2015, 40(8): 1087-1090.
doi: 10.13898/j.cnki.issn.1000-2200.2015.08.034
Abstract:
Objective:To evaluate the clinical value of real-time ultrasound-guiding right internal jugular vein catheter in infants with congenital heart disease.Methods:Seventy-six infants with congenital heart disease scheduled by right internal jugular vein catheter were randomly divided into the anatomic mark localization group(group A) and real-time ultrasound-guiding localization group(group B)(38 cases each group).The one-time puncture success rate,total puncture success rate,average number of puncture,puncture failure rate and complications in two groups were recorded.Results:The one-time puncture success rate in group B was significantly higher than that in group A(P<0.01).The difference of the total puncture success rate between group A and B was not statistically significant(P>0.05).The number of puncture and incidence of mistaken puncturing into carotid artery in group A were significantly higher than those in group A(P<0.01).The difference of the incidence of local hematoma between group A and B was not statistically significant(P>0.05).Conclusions:The real-time ultrasound-guiding right internal jugular vein catheter in infants with congenital heart disease can significantly improve the one-time puncture success rate,decrease the number of puncture and incidence of mistaken puncturing into carotid artery,which has the high practical value in clinic.
Objective:To evaluate the clinical value of real-time ultrasound-guiding right internal jugular vein catheter in infants with congenital heart disease.Methods:Seventy-six infants with congenital heart disease scheduled by right internal jugular vein catheter were randomly divided into the anatomic mark localization group(group A) and real-time ultrasound-guiding localization group(group B)(38 cases each group).The one-time puncture success rate,total puncture success rate,average number of puncture,puncture failure rate and complications in two groups were recorded.Results:The one-time puncture success rate in group B was significantly higher than that in group A(P<0.01).The difference of the total puncture success rate between group A and B was not statistically significant(P>0.05).The number of puncture and incidence of mistaken puncturing into carotid artery in group A were significantly higher than those in group A(P<0.01).The difference of the incidence of local hematoma between group A and B was not statistically significant(P>0.05).Conclusions:The real-time ultrasound-guiding right internal jugular vein catheter in infants with congenital heart disease can significantly improve the one-time puncture success rate,decrease the number of puncture and incidence of mistaken puncturing into carotid artery,which has the high practical value in clinic.
2015, 40(8): 1093-1096.
doi: 10.13898/j.cnki.issn.1000-2200.2015.08.036
Abstract:
Objective:To establish the reversed-phase ultra performance liquid chromatography(UPLC) with internal standard method for detecting the serum vitamin A level of children,in order to understand the school-age children vitamin A nutritional status,and provide reference in formulating the dietary nutrition plan.Methods:The 100 μl standard was added to the 100 ml serum of school aged children in Fuyang city Yingshang county,which was oscillated,mixed,extracted using 1.0 ml of hexane extraction and centrifugated.The supernatant was dried with N2,redissoluting using 200 μl of anhydrous ethanol,and which was determined by UPLC.The chromatographic column was the chromatographic conditions,which included Waters C18 column(2.1 mm×100 mm,1.7 μm),secondary array detector;mobile phase,acetonitrile:water(96:4) prodegassing before using.The detection wavelength was 325 nm,the column temperature was 40 ℃,the flow rate was 0.3 ml/min and the adding sample was 2 μl.Results:The serum vitamin A concentration in 360 school-age children was 0.072 8 to 0.728 μg/ml,the range of which showed a good linear relationship(r>0.999).The mean value of vitamin A was 39.6 μg/dl,CV was less than 5%.The lowest detection limit of vitamin A was 0.020 μg/ml,which could be detected within 4.0 min.Among 360 school aged children,the children with vitamin A level equal to or less than 20 μg/dl,equal to 30 μg/dl and more than or equal to 30 μg/dl were accounted for 1.11%,19.17% and 79.72%,respectively.Conclusions:The overall survey results meet the requirements of dietary nutrition plan.The reversed-phase ultra performance liquid chromatography with internal standard method in detecting the serum vitamin A level of children is fast,sensitive,accurate and reproducible.
Objective:To establish the reversed-phase ultra performance liquid chromatography(UPLC) with internal standard method for detecting the serum vitamin A level of children,in order to understand the school-age children vitamin A nutritional status,and provide reference in formulating the dietary nutrition plan.Methods:The 100 μl standard was added to the 100 ml serum of school aged children in Fuyang city Yingshang county,which was oscillated,mixed,extracted using 1.0 ml of hexane extraction and centrifugated.The supernatant was dried with N2,redissoluting using 200 μl of anhydrous ethanol,and which was determined by UPLC.The chromatographic column was the chromatographic conditions,which included Waters C18 column(2.1 mm×100 mm,1.7 μm),secondary array detector;mobile phase,acetonitrile:water(96:4) prodegassing before using.The detection wavelength was 325 nm,the column temperature was 40 ℃,the flow rate was 0.3 ml/min and the adding sample was 2 μl.Results:The serum vitamin A concentration in 360 school-age children was 0.072 8 to 0.728 μg/ml,the range of which showed a good linear relationship(r>0.999).The mean value of vitamin A was 39.6 μg/dl,CV was less than 5%.The lowest detection limit of vitamin A was 0.020 μg/ml,which could be detected within 4.0 min.Among 360 school aged children,the children with vitamin A level equal to or less than 20 μg/dl,equal to 30 μg/dl and more than or equal to 30 μg/dl were accounted for 1.11%,19.17% and 79.72%,respectively.Conclusions:The overall survey results meet the requirements of dietary nutrition plan.The reversed-phase ultra performance liquid chromatography with internal standard method in detecting the serum vitamin A level of children is fast,sensitive,accurate and reproducible.
2015, 40(8): 1099-1101.
doi: 10.13898/j.cnki.issn.1000-2200.2015.08.038
Abstract:
Objective:Compared with the control group,the levels of serum Hcy and VEGF in 1,7 and 14 day in patients with acute cerebral infarction were significantly higher(P<0.01),while the levels of serum EGF were significantly lower than those in control group(P<0.05~P<0.01 ).The levels of serum Hcy and VEGF in 1,7 and 14 d in large and medium infarction groups were significantly higher than those in small infarction group(P<0.01),but the levels of serum EGF in 1,7 and 14 day in large and medium infarction groups were significantly lower than those in small infarction group(P<0.01).Methods:One hundred and nine cases with acute cerebral infarction were divided into the large,medium and small infarction groups according to the infarct volume detected by MRI or CT at admission.The serum concentrations of Hcy,EGF and VEGF in three groups after 1,7 and 14 d of admission were detected.Thirty healthy people without acute cerebral infarction were set as the control group.Results:Compared with the control group,the levels of serum Hcy and VEGF in 1,7 and 14 day in patients with acute cerebral infarction were significantly higher(P<0.01), while the levels of serum EGF were significantly lower than those in control group(P<0.05~P<0.01 ).The levels of serum Hcy and VEGF in 1,7 and 14 d in large and medium infarction groups were significantly higher than those in small infarction group(P<0.01),but the levels of serum EGF in 1,7 and 14 day in large and medium infarction groups were significantly lower than those in small infarction group(P<0.01).Conclusions:The dynamic changes of the serum Hcy,EGF and VEGF levels in patients with acute cerebral infarction are associated with the infarct volume.The combined detection has important clinical significance in determining of the damage and evaluating the therapeutic effects of cerebral infarction.
Objective:Compared with the control group,the levels of serum Hcy and VEGF in 1,7 and 14 day in patients with acute cerebral infarction were significantly higher(P<0.01),while the levels of serum EGF were significantly lower than those in control group(P<0.05~P<0.01 ).The levels of serum Hcy and VEGF in 1,7 and 14 d in large and medium infarction groups were significantly higher than those in small infarction group(P<0.01),but the levels of serum EGF in 1,7 and 14 day in large and medium infarction groups were significantly lower than those in small infarction group(P<0.01).Methods:One hundred and nine cases with acute cerebral infarction were divided into the large,medium and small infarction groups according to the infarct volume detected by MRI or CT at admission.The serum concentrations of Hcy,EGF and VEGF in three groups after 1,7 and 14 d of admission were detected.Thirty healthy people without acute cerebral infarction were set as the control group.Results:Compared with the control group,the levels of serum Hcy and VEGF in 1,7 and 14 day in patients with acute cerebral infarction were significantly higher(P<0.01), while the levels of serum EGF were significantly lower than those in control group(P<0.05~P<0.01 ).The levels of serum Hcy and VEGF in 1,7 and 14 d in large and medium infarction groups were significantly higher than those in small infarction group(P<0.01),but the levels of serum EGF in 1,7 and 14 day in large and medium infarction groups were significantly lower than those in small infarction group(P<0.01).Conclusions:The dynamic changes of the serum Hcy,EGF and VEGF levels in patients with acute cerebral infarction are associated with the infarct volume.The combined detection has important clinical significance in determining of the damage and evaluating the therapeutic effects of cerebral infarction.
2015, 40(8): 1102-1104.
doi: 10.13898/j.cnki.issn.1000-2200.2015.08.039
Abstract:
Objective:To investigate the relationships between the levels of retinol binding protein 4(RBP4) and lipoprotein associated phospholipase A2(Lp-PLA2),and stability of deterioration of coronary heart disease and selective coronary angiography results.Methods:Eighty-nine patients with coronary heart disease were divided into the control group(without vessel lesion),1 vessel lesion group,2 branches lesion group and 3 branches lesion group according to the results of coronary angiography.The levels of Lp-PLA2 and RBP4 in 4 groups before angiography were detected by enzyme-linked immunosorbent assay.Results:The levels of Lp-PLA2 and RBP4 in 3 branches lesion group were significantly higher than those in control group,1 vessel lesion group and 2 branches lesion group(P<0.01).The level of Lp-PLA2 in 2 branches lesion group was significantly higher than those in control group and 1 vessel lesion group(P<0.01).The difference of the Lp-PLA2 levels between 1 branch lesion group and control group was not statistically significant(P>0.05).The difference of the RBP4 levels between 1 branch lesion group,2 branches lesion group 2 and control group were not statistically significant(P>0.05).Conclusions:The levels of serum Lp-PLA2 and RBP4 in patients with coronary heart disease are related to the number of coronary artery lesion,which can predict the stenosis degree of coronary artery in a certain extent.
Objective:To investigate the relationships between the levels of retinol binding protein 4(RBP4) and lipoprotein associated phospholipase A2(Lp-PLA2),and stability of deterioration of coronary heart disease and selective coronary angiography results.Methods:Eighty-nine patients with coronary heart disease were divided into the control group(without vessel lesion),1 vessel lesion group,2 branches lesion group and 3 branches lesion group according to the results of coronary angiography.The levels of Lp-PLA2 and RBP4 in 4 groups before angiography were detected by enzyme-linked immunosorbent assay.Results:The levels of Lp-PLA2 and RBP4 in 3 branches lesion group were significantly higher than those in control group,1 vessel lesion group and 2 branches lesion group(P<0.01).The level of Lp-PLA2 in 2 branches lesion group was significantly higher than those in control group and 1 vessel lesion group(P<0.01).The difference of the Lp-PLA2 levels between 1 branch lesion group and control group was not statistically significant(P>0.05).The difference of the RBP4 levels between 1 branch lesion group,2 branches lesion group 2 and control group were not statistically significant(P>0.05).Conclusions:The levels of serum Lp-PLA2 and RBP4 in patients with coronary heart disease are related to the number of coronary artery lesion,which can predict the stenosis degree of coronary artery in a certain extent.
2015, 40(8): 1105-1107.
doi: 10.13898/j.cnki.issn.1000-2200.2015.08.040
Abstract:
Objective:To investigate the value of semen routine,biochemical criterion and spermatogenic cells in the diagnosis of azoospermia.Methods:The seminal spermatogenic cells was detected using the modified papanicolaou staining.The patients were divided into the group A(32 cases with spermatogenic cells) and group B(38 cases without spermatogenic cells) according to the presence or absence of seminal spermatogenic cells,30 normal men were set as the control group.The semen volume and pH,seminal plasma fructose content,neutral α-glycosidase activity and testicular biopsy in three group were detected.Results:The differences of the semen volume and pH and neutral α-glycosidase activity between group A and control group were not statistically significant(P>0.05),the seminal plasma fructose content in group A was significantly higher than that in group B and control group(P<0.01),and the semen volume and pH,and neutral α- glucosidase activity in group B were significantly lower than those in group A(P<0.01).The coincidence rates of the combined detection of seminal spermatogenic cells,semen routine and biochemical criterion,and testicular biopsy in the dagnoisis of obstructive and non-obstructive azzospermia were 97.3%(36/37) and 97.1%(33/34),respectively.Conclusions:The joint detection of seminal spermatogenic cells,semen routine and biochemical criterion can be used as an important indicator in differentiating the obstructive and non-obstructive azzospermia,which has important significance in guiding clinical treatment.
Objective:To investigate the value of semen routine,biochemical criterion and spermatogenic cells in the diagnosis of azoospermia.Methods:The seminal spermatogenic cells was detected using the modified papanicolaou staining.The patients were divided into the group A(32 cases with spermatogenic cells) and group B(38 cases without spermatogenic cells) according to the presence or absence of seminal spermatogenic cells,30 normal men were set as the control group.The semen volume and pH,seminal plasma fructose content,neutral α-glycosidase activity and testicular biopsy in three group were detected.Results:The differences of the semen volume and pH and neutral α-glycosidase activity between group A and control group were not statistically significant(P>0.05),the seminal plasma fructose content in group A was significantly higher than that in group B and control group(P<0.01),and the semen volume and pH,and neutral α- glucosidase activity in group B were significantly lower than those in group A(P<0.01).The coincidence rates of the combined detection of seminal spermatogenic cells,semen routine and biochemical criterion,and testicular biopsy in the dagnoisis of obstructive and non-obstructive azzospermia were 97.3%(36/37) and 97.1%(33/34),respectively.Conclusions:The joint detection of seminal spermatogenic cells,semen routine and biochemical criterion can be used as an important indicator in differentiating the obstructive and non-obstructive azzospermia,which has important significance in guiding clinical treatment.
2015, 40(8): 1108-1110.
doi: 10.13898/j.cnki.issn.1000-2200.2015.08.041
Abstract:
Objective:To analyze the hepatitis C antibody(Anti-HCV),HCV-RNA and genotype in 5 080 patients with hepatitis C.Methods:The levels of Anti-HCV and HCV-RNA in all patients were determined by automatic enhanced luminescence immunity analyzer and quantitative fluorescent PCR,respectively.The genotypes in the patients with more than or equal to 103 of HCV-RNA were detected.Results:The positive rates of Anti-HCV and HCV-RNA were 99.8% and 49.1%,respectively.The ages and antibody content in positive HCV-RNA patients were significantly higher than those in the negative HCV-RNA patients(P<0.01).Among the 1 723 positive HCV-RNA specimens,the 1b and 2a genotypes accounted for 59.49% and 36.20%,respectively,the total ratio of 1b and 2a genotypes was 95.69%.The unusual types of 3b and 4,and mixed infection types of 1b/2a and 1b/4 also were detected.Conclusions:The Anti-HCV content and viral load are lack of correlation,which can not be used as the observation indexes in estimating the treatment.The quantitation of HCV-RNA can be used to evaluate the curative effect and prognosis of patients with hepatitis C.The 1b and 2a are the major genotypes in patients with hepatitis C.To analyze the genotype of the positive HCV-RNA patients can provide the basis in personalized therapy.
Objective:To analyze the hepatitis C antibody(Anti-HCV),HCV-RNA and genotype in 5 080 patients with hepatitis C.Methods:The levels of Anti-HCV and HCV-RNA in all patients were determined by automatic enhanced luminescence immunity analyzer and quantitative fluorescent PCR,respectively.The genotypes in the patients with more than or equal to 103 of HCV-RNA were detected.Results:The positive rates of Anti-HCV and HCV-RNA were 99.8% and 49.1%,respectively.The ages and antibody content in positive HCV-RNA patients were significantly higher than those in the negative HCV-RNA patients(P<0.01).Among the 1 723 positive HCV-RNA specimens,the 1b and 2a genotypes accounted for 59.49% and 36.20%,respectively,the total ratio of 1b and 2a genotypes was 95.69%.The unusual types of 3b and 4,and mixed infection types of 1b/2a and 1b/4 also were detected.Conclusions:The Anti-HCV content and viral load are lack of correlation,which can not be used as the observation indexes in estimating the treatment.The quantitation of HCV-RNA can be used to evaluate the curative effect and prognosis of patients with hepatitis C.The 1b and 2a are the major genotypes in patients with hepatitis C.To analyze the genotype of the positive HCV-RNA patients can provide the basis in personalized therapy.
2015, 40(8): 1111-1112.
doi: 10.13898/j.cnki.issn.1000-2200.2015.08.042
Abstract:
Objective:To explore the effects of system link education in improving the cognition on preventing the disulfiram reaction of patients.Methods:One hundred and ninety patients with possible occurrence of disulfiram reaction during intravenous infusion were randomly divided into the control group and observation group(95 cases each group).The control group and observation group were educated with general education and system link education,respectively.The education effects in two groups were observed by questionnaire.Results:The scores of the degree of mastering disulfiram reaction knowledge,degree of cognition of disulfiram reaction harm,active protection and compliance behavior in observation group were significantly higher than those in control group(P<0.01).Conclusions:System link education can effectively improve the degree of cognition of disulfiram reaction harm,compliance behavior and prevent the occurrence of disulfiram reaction of patients.
Objective:To explore the effects of system link education in improving the cognition on preventing the disulfiram reaction of patients.Methods:One hundred and ninety patients with possible occurrence of disulfiram reaction during intravenous infusion were randomly divided into the control group and observation group(95 cases each group).The control group and observation group were educated with general education and system link education,respectively.The education effects in two groups were observed by questionnaire.Results:The scores of the degree of mastering disulfiram reaction knowledge,degree of cognition of disulfiram reaction harm,active protection and compliance behavior in observation group were significantly higher than those in control group(P<0.01).Conclusions:System link education can effectively improve the degree of cognition of disulfiram reaction harm,compliance behavior and prevent the occurrence of disulfiram reaction of patients.
2015, 40(8): 1113-1115.
doi: 10.13898/j.cnki.issn.1000-2200.2015.08.043
Abstract:
Objective:To investigate the effects of continuity care on elderly patients with diabetes.Methods:From June 2012 to February 2014,82 elderly diabetic patients were randomly divided into the control group(42 cases) and observation group(40 cases).The control group and observation group were routinely followed up and continuity care based on the routine following up,respectively.The compliances of diet,exercise,treatment and blood glucose monitoring in two groups were observed.The glycosylated hemoglobin and medical expenses between two groups were compared after 12 weeks and 24 weeks of discharge.Results:Forty cases in observation group and 36 cases in control group were followed-up.The compliances of exercise,medication and blood glucose monitoring in observation group were better than those in control group after 12 weeks and 24 weeks of discharge(P<0.01).The difference of the compliance of diet between two groups was not statistically significant after 12 weeks of discharge(P>0.05).The material cost in observation group was higher than that in control group after discharge for 1 to 12 weeks(P<0.01).After discharge for 1 to 24 weeks,the health care cost in observation group was lower than that in control group(P<0.01).The differences of drug and material between two groups were not statistically significant(P>0.05).Conclusions:The continuity care can improve the compliance of treatment and maintain stable blood glucose of elderly patients with diabetes after discharge.
Objective:To investigate the effects of continuity care on elderly patients with diabetes.Methods:From June 2012 to February 2014,82 elderly diabetic patients were randomly divided into the control group(42 cases) and observation group(40 cases).The control group and observation group were routinely followed up and continuity care based on the routine following up,respectively.The compliances of diet,exercise,treatment and blood glucose monitoring in two groups were observed.The glycosylated hemoglobin and medical expenses between two groups were compared after 12 weeks and 24 weeks of discharge.Results:Forty cases in observation group and 36 cases in control group were followed-up.The compliances of exercise,medication and blood glucose monitoring in observation group were better than those in control group after 12 weeks and 24 weeks of discharge(P<0.01).The difference of the compliance of diet between two groups was not statistically significant after 12 weeks of discharge(P>0.05).The material cost in observation group was higher than that in control group after discharge for 1 to 12 weeks(P<0.01).After discharge for 1 to 24 weeks,the health care cost in observation group was lower than that in control group(P<0.01).The differences of drug and material between two groups were not statistically significant(P>0.05).Conclusions:The continuity care can improve the compliance of treatment and maintain stable blood glucose of elderly patients with diabetes after discharge.
2015, 40(8): 1116-1118,1120.
doi: 10.13898/j.cnki.issn.1000-2200.2015.08.044
Abstract:
Objective:To explore the effects of the predictive nursing on pre-hospital first aid of patients with acute myocardial infarction.Methods:One hundred and twenty-four patients with acute myocardial infarction were randomly divided into the control group and observation group.The control group and observation group were treated with the routine nursing and predictive nursing,respectively.The effective rescue time,rescue success rate,average hospital stay and incidence of complications between two groups were compared.Results:The effective rescue time and average hospital stay in observation group were shorter than that in control group,the rescue success rate in observation group was higher than that in control group(P<0.01).The incidences of ventricular arrhythmia,left heart failure and cardiac shock in observation group were lower than that in control group(P<0.01).Conclusions:The predictive nursing can improve the rescue success rate,shorten the effective rescue time of pre-hospital first aid and hospital stay,reduce the incidence of complications and improve the nursing quality of the patients.
Objective:To explore the effects of the predictive nursing on pre-hospital first aid of patients with acute myocardial infarction.Methods:One hundred and twenty-four patients with acute myocardial infarction were randomly divided into the control group and observation group.The control group and observation group were treated with the routine nursing and predictive nursing,respectively.The effective rescue time,rescue success rate,average hospital stay and incidence of complications between two groups were compared.Results:The effective rescue time and average hospital stay in observation group were shorter than that in control group,the rescue success rate in observation group was higher than that in control group(P<0.01).The incidences of ventricular arrhythmia,left heart failure and cardiac shock in observation group were lower than that in control group(P<0.01).Conclusions:The predictive nursing can improve the rescue success rate,shorten the effective rescue time of pre-hospital first aid and hospital stay,reduce the incidence of complications and improve the nursing quality of the patients.
2015, 40(8): 1118-1120.
doi: 10.13898/j.cnki.issn.1000-2200.2015.08.045
Abstract:
Objective:To investigate the effects of emergency care on the patients with acute severe viral myocarditis complicated with acute renal failure.Methods:Sixty patients with acute severe viral myocarditis complicated with acute renal failure were emergently nursed,which included the early recognition of the disease,malignant arrhythmias,mechanical ventilation,acute renal failure and drug use.The indexes of cardiac function and renal function were observed after emergency care.Results:After active treatment and nursing intervention of 60 patients,the levels of serum creatinine,urea nitrogen,heart rate and cardiac troponin I were significantly lower than those of before emergency care,the urine volume,systolic and diastolic blood pressure were significantly higher than those of before emergency care(P<0.01).Conclusions:The emergency care on the patients with acute severe viral myocarditis complicated with acute renal failure can significantly improve the cardiac and renal function,and prognosis of patients.
Objective:To investigate the effects of emergency care on the patients with acute severe viral myocarditis complicated with acute renal failure.Methods:Sixty patients with acute severe viral myocarditis complicated with acute renal failure were emergently nursed,which included the early recognition of the disease,malignant arrhythmias,mechanical ventilation,acute renal failure and drug use.The indexes of cardiac function and renal function were observed after emergency care.Results:After active treatment and nursing intervention of 60 patients,the levels of serum creatinine,urea nitrogen,heart rate and cardiac troponin I were significantly lower than those of before emergency care,the urine volume,systolic and diastolic blood pressure were significantly higher than those of before emergency care(P<0.01).Conclusions:The emergency care on the patients with acute severe viral myocarditis complicated with acute renal failure can significantly improve the cardiac and renal function,and prognosis of patients.
2015, 40(8): 1121-1124.
doi: 10.13898/j.cnki.issn.1000-2200.2015.08.046
Abstract:
Objective:To investigate the nursing method and effects in the dilated cardiomyopathy complicated with malignant arrhythmia patients treated with cardiac resynchronization pacing defibrillator.Methods:Ninety patients with the dilated cardiomyopathy complicated with malignant arrhythmia treated with cardiac resynchronization pacing defibrillator were randomly divided into the control group(treatment with routine care) and observation group(treatment with nursing intervention)(45 cases each group).The quality of life in two groups was evaluated by WHO quality of life scale(WHOQOL-BREF) before and after treatment.The changes of clinical indicators,treatment effect,heart function classification,postoperative adverse events and satisfaction were compared between two groups.Results:The LÜEF,6 min walking distance,WHOQOL-BREF score(including physical field,psychological field,social field and environment field) in two groups after treatment were significantly higher than those in before treatment(P<0.01),but the QRS wave width and LÜEDD after treatment were significantly lower than those in before treatment(P<0.01).The LÜEF and 6 min walking distance in observation group were significantly larger than those in control group(P<0.01),the QRS wave width and LÜEDD in observation group were significantly less than those in control group(P<0.01).The WHOQOL-BREF score(including physical field,psychological field,social field and environment field),total effective rate and nursing satisfaction in observation group were significantly higher than those in control group(P<0.05 to P<0.01).Heart function classification in observation group was significantly better than that in control group(P<0.01).The difference of the incidence of postoperative adverse events between two groups was not statistically significant(P>0.05).Conclusions:When the patients with dilated cardiomyopathy complicated with malignant arrhythmia are treated with cardiac resynchronization pacing defibrillator,the effective nursing intervention can significantly improve heart function and quality of life.
Objective:To investigate the nursing method and effects in the dilated cardiomyopathy complicated with malignant arrhythmia patients treated with cardiac resynchronization pacing defibrillator.Methods:Ninety patients with the dilated cardiomyopathy complicated with malignant arrhythmia treated with cardiac resynchronization pacing defibrillator were randomly divided into the control group(treatment with routine care) and observation group(treatment with nursing intervention)(45 cases each group).The quality of life in two groups was evaluated by WHO quality of life scale(WHOQOL-BREF) before and after treatment.The changes of clinical indicators,treatment effect,heart function classification,postoperative adverse events and satisfaction were compared between two groups.Results:The LÜEF,6 min walking distance,WHOQOL-BREF score(including physical field,psychological field,social field and environment field) in two groups after treatment were significantly higher than those in before treatment(P<0.01),but the QRS wave width and LÜEDD after treatment were significantly lower than those in before treatment(P<0.01).The LÜEF and 6 min walking distance in observation group were significantly larger than those in control group(P<0.01),the QRS wave width and LÜEDD in observation group were significantly less than those in control group(P<0.01).The WHOQOL-BREF score(including physical field,psychological field,social field and environment field),total effective rate and nursing satisfaction in observation group were significantly higher than those in control group(P<0.05 to P<0.01).Heart function classification in observation group was significantly better than that in control group(P<0.01).The difference of the incidence of postoperative adverse events between two groups was not statistically significant(P>0.05).Conclusions:When the patients with dilated cardiomyopathy complicated with malignant arrhythmia are treated with cardiac resynchronization pacing defibrillator,the effective nursing intervention can significantly improve heart function and quality of life.
2015, 40(8): 1125-1127.
doi: 10.13898/j.cnki.issn.1000-2200.2015.08.047
Abstract:
Objective:To explore the effects of humane nursing on the adaptation and coping ability of mother role in primipara during puerperium.Methods:The awaiting delivery 80 primiparas with regular pregnancy care were randomly divided into the control group and observation group(40 cases each group).The control group and observation group were nursed with the common nursing and strengthening humane nursing intervention during puerperium,respectively.The adaptation and coping ability of mother role between two groups were compared using the mother role adjustment questionnaire and the medical coping modes questionaire.Results:After delivery for 1 month,the adaptation and coping ability of mother role in observation group was significantly better than those in control group(P<0.01).The score in observation group(19.86±4.97) was significantly higher than that in control group(16.21±4.06)(P<0.01).The scores of avoidance and resignation responses score in observation group[(13.12±3.28) &(9.22±2.31)] were significantly lower than those in control group[(15.79±3.95) &(12.45±3.12)],respectively(P<0.05).Conclusions:The humanistic nursing invention in primipara during puerperium can quickly make them get into the mother's role and actively deal with the problem.
Objective:To explore the effects of humane nursing on the adaptation and coping ability of mother role in primipara during puerperium.Methods:The awaiting delivery 80 primiparas with regular pregnancy care were randomly divided into the control group and observation group(40 cases each group).The control group and observation group were nursed with the common nursing and strengthening humane nursing intervention during puerperium,respectively.The adaptation and coping ability of mother role between two groups were compared using the mother role adjustment questionnaire and the medical coping modes questionaire.Results:After delivery for 1 month,the adaptation and coping ability of mother role in observation group was significantly better than those in control group(P<0.01).The score in observation group(19.86±4.97) was significantly higher than that in control group(16.21±4.06)(P<0.01).The scores of avoidance and resignation responses score in observation group[(13.12±3.28) &(9.22±2.31)] were significantly lower than those in control group[(15.79±3.95) &(12.45±3.12)],respectively(P<0.05).Conclusions:The humanistic nursing invention in primipara during puerperium can quickly make them get into the mother's role and actively deal with the problem.
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