Author Login
Experts Review
Academic Editor
Editor-in-chief
2016 Vol. 41, No. 5
Display Method:
2016, 41(5): 561-562,566.
doi: 10.13898/j.cnki.issn.1000-2200.2016.05.001
Abstract:
Objective:To establish a three-dimensional(3D) visualization model of cerebral superior frontal sulcus in a healthy adult people using MR image for exploring the anatomical characteristics of the superior frontal sulcus and application in brain stereotactic surgery.Methods:The brain slice MR scanning in one healthy adult female was harvested,the data of which was inputted to 3D-Doctor software.The 3D visualization model was reconstructed,and marked with different colors by the manual partition method.Results:The 3D visualization schema graph of cerebral superior frontal sulcus was constructed,which showed successfully the three-dimensional shape of cerebral superior frontal sulcus,lateral ventricle,brain surface and their structural relationships with surrounding brain.Conclusions:The 3D visualization model of cerebral superior frontal sulcus has an important value in the identification of the anatomical structure of superior frontal sulcus and design of stereotactic surgery.
Objective:To establish a three-dimensional(3D) visualization model of cerebral superior frontal sulcus in a healthy adult people using MR image for exploring the anatomical characteristics of the superior frontal sulcus and application in brain stereotactic surgery.Methods:The brain slice MR scanning in one healthy adult female was harvested,the data of which was inputted to 3D-Doctor software.The 3D visualization model was reconstructed,and marked with different colors by the manual partition method.Results:The 3D visualization schema graph of cerebral superior frontal sulcus was constructed,which showed successfully the three-dimensional shape of cerebral superior frontal sulcus,lateral ventricle,brain surface and their structural relationships with surrounding brain.Conclusions:The 3D visualization model of cerebral superior frontal sulcus has an important value in the identification of the anatomical structure of superior frontal sulcus and design of stereotactic surgery.
2016, 41(5): 563-566.
doi: 10.13898/j.cnki.issn.1000-2200.2016.05.002
Abstract:
Objective:To explore the protective effects of carbachol combined with dietary fiber on the intestinal barrier in rats with burn shock.Methods:The animal model of 80 Wistar rats with 30% TBSA Ⅲ° burn were established,and randomly divided into the saline injection group(group A),dietary fiber treatment group(B group),carlbachol treatment group(groupC) and carlbachol combined with dietary fiber treatment group(group D)(20 rats each group).The 4 rats in each group were sacrificed at 6,12,24,48 and 72 hours after injury,respetcively.The 4 normal rats were set as the control group(group N).The pathomorphological change of small intestine was observed under light microscope,the plasma levels of endotoxin in portal vein and D-lactic acid in abdominal aorta were detected.Results:The damage of the intestinal tissue in each burn group was significant.The plasma levels of endotoxin and D-lactic acid in all burn rats were significantly higher than those in group N,which arrived at peak at 12 to 24 hours after injury,and did not recover until 72 hours after injury.The treatment of the carlbachol combined with dietary fiber of single carlbachol or dietary fiber could significantly decrease the levels of the plasma endotoxin and D-lactic acid(P<0.05 to P<0.01).Conclusions:The early application of carlbachol combined with dietary fiber has markedly protective effect on intestinal barrier in burn rats,the treatment effect of which is better than that in single treatment of carbachol or dietary fiber to some exent.
Objective:To explore the protective effects of carbachol combined with dietary fiber on the intestinal barrier in rats with burn shock.Methods:The animal model of 80 Wistar rats with 30% TBSA Ⅲ° burn were established,and randomly divided into the saline injection group(group A),dietary fiber treatment group(B group),carlbachol treatment group(groupC) and carlbachol combined with dietary fiber treatment group(group D)(20 rats each group).The 4 rats in each group were sacrificed at 6,12,24,48 and 72 hours after injury,respetcively.The 4 normal rats were set as the control group(group N).The pathomorphological change of small intestine was observed under light microscope,the plasma levels of endotoxin in portal vein and D-lactic acid in abdominal aorta were detected.Results:The damage of the intestinal tissue in each burn group was significant.The plasma levels of endotoxin and D-lactic acid in all burn rats were significantly higher than those in group N,which arrived at peak at 12 to 24 hours after injury,and did not recover until 72 hours after injury.The treatment of the carlbachol combined with dietary fiber of single carlbachol or dietary fiber could significantly decrease the levels of the plasma endotoxin and D-lactic acid(P<0.05 to P<0.01).Conclusions:The early application of carlbachol combined with dietary fiber has markedly protective effect on intestinal barrier in burn rats,the treatment effect of which is better than that in single treatment of carbachol or dietary fiber to some exent.
2016, 41(5): 567-569,573.
doi: 10.13898/j.cnki.issn.1000-2200.2016.05.003
Abstract:
Objective:To investigate the effects of the cross-growth titanium plate on fixing the type IV Salter-Harries epiphyses injury in animal experiment.Methods:Twenty-four healthy goats with the age of 6 to 7 weeks were randomly divided into the blank group,kirschner group and across-growth titanium plate group(8 goats each group).The animal models of the kirschner group and across-growth titanium plate group were established by kirschner drilling the distal epiphyses in two sides of humerus,which was fixed using across-growth titanium plate and kirschner,respectively.The biomechanical testing of 4 goats from each group after 8 or 12 weeks of operation were implemented and compared.Results:After 8 and 12 weeks of operation,the differences of the yield strength,maximum load,maximum elastic modulus and breaking point between blank group and across-growth titanium plate group were not statistically significant(P >0.05),and each indicator in the two groups were better than those in kirschner group(P<0.01).Conclusions:The treatment of type Ⅳ Salter-Harries epiphyses injury with cross-growth titanium plate can effectively meet the fixation strength of the bio-mechanics,which can provide a relatively stable setting to accelerate the repair process of the epiphyses injury.
Objective:To investigate the effects of the cross-growth titanium plate on fixing the type IV Salter-Harries epiphyses injury in animal experiment.Methods:Twenty-four healthy goats with the age of 6 to 7 weeks were randomly divided into the blank group,kirschner group and across-growth titanium plate group(8 goats each group).The animal models of the kirschner group and across-growth titanium plate group were established by kirschner drilling the distal epiphyses in two sides of humerus,which was fixed using across-growth titanium plate and kirschner,respectively.The biomechanical testing of 4 goats from each group after 8 or 12 weeks of operation were implemented and compared.Results:After 8 and 12 weeks of operation,the differences of the yield strength,maximum load,maximum elastic modulus and breaking point between blank group and across-growth titanium plate group were not statistically significant(P >0.05),and each indicator in the two groups were better than those in kirschner group(P<0.01).Conclusions:The treatment of type Ⅳ Salter-Harries epiphyses injury with cross-growth titanium plate can effectively meet the fixation strength of the bio-mechanics,which can provide a relatively stable setting to accelerate the repair process of the epiphyses injury.
2016, 41(5): 570-573.
doi: 10.13898/j.cnki.issn.1000-2200.2016.05.004
Abstract:
Objective:To explore the expression of programmed cell death 4(Pdcd4) gene in esophageal squamous cell carcinoma,and relationship between the expression level of Pdcd4 and occurrence and development of tumor.Methods:The expressions of Pdcd4 mRNA in 60 esophageal squamous cell carcinoma tissues and adjacent normal tissue were detected by real-time polymerase chain reaction,and the expressions of Pdcd4 protein in 178 esophageal squamous cell carcinoma tissues and adjacent normal tissue were detected by immunohistochemical method.Results:The expression of Pdcd4 mRNA in esophageal squamous cell carcinoma tissue were significantly lower than that in adjacent normal tissue(P<0.01).The positive expression rate of Pdcd4 in esophageal squamous cell carcinoma tissue(47.2%) were significantly lower than that in adjacent normal tissue(100.0%)(P<0.01).The expression of Pdcd4 was correlation with tumor differentiation,the positive expression rates of Pdcd4 in high,moderate and low differentiation esophageal squamous cell carcinoma tissue were 71.4%,43.4% and 30.2%,respectively.The positive expression rate of Pdcd4 in high differentiation esophageal squamous cell carcinoma tissue was higher than that in moderate and low differentiation esophageal squamous cell carcinoma tissue,the difference of the positive expression rate of Pdcd4 between moderate and low differentiation esophageal squamous cell carcinoma was not statistically significant(P >0.05).The difference of the positive expression rate of Pdcd4 between age of patient,tumor size,TNM staging and N staging were not statistically significant(P >0.05).Conclusions:The abnormal expression of Pdcd4 is correlation with the occurrence and development of esophageal squamous cell carcinoma.
Objective:To explore the expression of programmed cell death 4(Pdcd4) gene in esophageal squamous cell carcinoma,and relationship between the expression level of Pdcd4 and occurrence and development of tumor.Methods:The expressions of Pdcd4 mRNA in 60 esophageal squamous cell carcinoma tissues and adjacent normal tissue were detected by real-time polymerase chain reaction,and the expressions of Pdcd4 protein in 178 esophageal squamous cell carcinoma tissues and adjacent normal tissue were detected by immunohistochemical method.Results:The expression of Pdcd4 mRNA in esophageal squamous cell carcinoma tissue were significantly lower than that in adjacent normal tissue(P<0.01).The positive expression rate of Pdcd4 in esophageal squamous cell carcinoma tissue(47.2%) were significantly lower than that in adjacent normal tissue(100.0%)(P<0.01).The expression of Pdcd4 was correlation with tumor differentiation,the positive expression rates of Pdcd4 in high,moderate and low differentiation esophageal squamous cell carcinoma tissue were 71.4%,43.4% and 30.2%,respectively.The positive expression rate of Pdcd4 in high differentiation esophageal squamous cell carcinoma tissue was higher than that in moderate and low differentiation esophageal squamous cell carcinoma tissue,the difference of the positive expression rate of Pdcd4 between moderate and low differentiation esophageal squamous cell carcinoma was not statistically significant(P >0.05).The difference of the positive expression rate of Pdcd4 between age of patient,tumor size,TNM staging and N staging were not statistically significant(P >0.05).Conclusions:The abnormal expression of Pdcd4 is correlation with the occurrence and development of esophageal squamous cell carcinoma.
2016, 41(5): 574-576,579.
doi: 10.13898/j.cnki.issn.1000-2200.2016.05.005
Abstract:
Objective:To explore the relationship between diabetic retinopathy(DR) and serum 25-hydroxy vitamin D(25-OH-VD) level in patients with type 2 diabetes mellitus(T2DM).Methods:The 162 T2DM patients were divided into the single diabetes mellitus group(DM group,66 cases),non-proliferative diabetic retinopathy(NPDR group,52 cases) and proliferative diabetic retinopathy(PDR group,44 cases) according to the fundus oculi results.The clinical characteristics and biochemical parameters were investigated to analyze the risk factors of DR.Results:The duration and glycated hemoglobin(HbA1C) levels in PDR and NPDR groups were higher than those in DM group(P<0.05 to P<0.01),and the duration and HbA1C level in PDR group were higher than those in NPDR group(P<0.05 to P<0.01).The 25-OH-VD levels in PDR and NPDR groups were significantly less than that in DM group(P<0.01),and the 25-OH-VD level in PDR group was significantly lower than that in NPDR group(P<0.01).The systolic blood pressure(SBP) in PDR group was higher than that in DM group(P<0.05),but the difference of the SBP level between PDR and NPDR group was not statistically significant(P >0.05).Correlation analysis showed that the duration,SBP and HbA1C level of patients were positive correlation with DR(P<0.05 to P<0.01),and the level of serum 25-OH-VD were negative correlation with DR(P<0.01).Multiple logistic regression analysis showed that the duration and HbA1C level of the patients were the risk factors of DR(P<0.05 to P<0.01),and the 25-OH-VD level was a protective factor of DR(P<0.01).Conclusions:The serum level of 25-OH-VD is associated with the occurrence and severity of DR,and it is an independent risk factor of DR.
Objective:To explore the relationship between diabetic retinopathy(DR) and serum 25-hydroxy vitamin D(25-OH-VD) level in patients with type 2 diabetes mellitus(T2DM).Methods:The 162 T2DM patients were divided into the single diabetes mellitus group(DM group,66 cases),non-proliferative diabetic retinopathy(NPDR group,52 cases) and proliferative diabetic retinopathy(PDR group,44 cases) according to the fundus oculi results.The clinical characteristics and biochemical parameters were investigated to analyze the risk factors of DR.Results:The duration and glycated hemoglobin(HbA1C) levels in PDR and NPDR groups were higher than those in DM group(P<0.05 to P<0.01),and the duration and HbA1C level in PDR group were higher than those in NPDR group(P<0.05 to P<0.01).The 25-OH-VD levels in PDR and NPDR groups were significantly less than that in DM group(P<0.01),and the 25-OH-VD level in PDR group was significantly lower than that in NPDR group(P<0.01).The systolic blood pressure(SBP) in PDR group was higher than that in DM group(P<0.05),but the difference of the SBP level between PDR and NPDR group was not statistically significant(P >0.05).Correlation analysis showed that the duration,SBP and HbA1C level of patients were positive correlation with DR(P<0.05 to P<0.01),and the level of serum 25-OH-VD were negative correlation with DR(P<0.01).Multiple logistic regression analysis showed that the duration and HbA1C level of the patients were the risk factors of DR(P<0.05 to P<0.01),and the 25-OH-VD level was a protective factor of DR(P<0.01).Conclusions:The serum level of 25-OH-VD is associated with the occurrence and severity of DR,and it is an independent risk factor of DR.
2016, 41(5): 577-579.
doi: 10.13898/j.cnki.issn.1000-2200.2016.05.006
Abstract:
Objective:To investigate the diagnosis,surgical indications and timing of surgical treatment of infective endocarditis complicated with cerebral vascular complications for summarizing the clinical experience.Methods:The data of the 40 patients with infective endocarditis complicated with preoperative complication before operation were retrospectively analyzed.After admission,the patients were treated with sensitive antibiotics according to the blood culture finding combined with nerve nutrition.The appropriate timing of surgery was selected,thorough removing the lesion and correcting cardiac malformations were implemented during the period of operation.After operation,the patients were treated with cardiotonic,diuresis and sensitive antibiotics.Results:The early postoperative death in 6 cases,recurrence of cerebral hemorrhage in 2 cases,malignant arrhythmia in 2 cases,severe pulmonary infection in 1 case,low cardiac output syndrome in 1 case and circulatory failure secondary to renal failure in 1 case were found,34 cases cured.Conclusions:The surgical treatment effect in patients with infective endocarditis complicated with cerebral vascular complication is satisfaction.The early diagnosis,reasonable grasping the timing of surgery,thorough removing the lesions,postoperative standard anti-infection and anticoagulant therapy are the key.
Objective:To investigate the diagnosis,surgical indications and timing of surgical treatment of infective endocarditis complicated with cerebral vascular complications for summarizing the clinical experience.Methods:The data of the 40 patients with infective endocarditis complicated with preoperative complication before operation were retrospectively analyzed.After admission,the patients were treated with sensitive antibiotics according to the blood culture finding combined with nerve nutrition.The appropriate timing of surgery was selected,thorough removing the lesion and correcting cardiac malformations were implemented during the period of operation.After operation,the patients were treated with cardiotonic,diuresis and sensitive antibiotics.Results:The early postoperative death in 6 cases,recurrence of cerebral hemorrhage in 2 cases,malignant arrhythmia in 2 cases,severe pulmonary infection in 1 case,low cardiac output syndrome in 1 case and circulatory failure secondary to renal failure in 1 case were found,34 cases cured.Conclusions:The surgical treatment effect in patients with infective endocarditis complicated with cerebral vascular complication is satisfaction.The early diagnosis,reasonable grasping the timing of surgery,thorough removing the lesions,postoperative standard anti-infection and anticoagulant therapy are the key.
2016, 41(5): 580-583.
doi: 10.13898/j.cnki.issn.1000-2200.2016.05.007
Abstract:
Objective:To study the risk factors for osteoporosis(OP)in female patients with osteoarthritis(OA).Methods:The bone mineral density(BMD) in the lumbar vertebrae(L1~4),femoral neck and total femoral area of 300 female patients with OA and 101 female healthy subjects were measured by dual energy X-ray absorptiometry.The risk factors for OP were analyzed statistically in each group.Results:The incidence of OP in the female patients with OA was significant higher than that in the healthy subjects(P<0.01).The BMD of all positions in the female patients with OA was lower than that in the healthy subjects(P<0.01).Of all the patients with OA,those who had been diagnosed as having OP had lower BMD than those who had not (P<0.01).The BMD in the menopause group with OA was lower than that in the pre-menopausal group.Of all the patients with OA,the OP group had elder ages,longer years of menopause and more numbers of motherhood.And the differences were all statistically significant(P<0.01).The probability of osteoporotic fracture in patients with OA was obviously higher than that in healthy subjects in the next 10 years(P<0.01).Conclusions:Compared with the healthy subjects,patients with OA are more easily affected by OP and osteoporotic fracture.The incidence of OP is related to several risk factors such as elder ages,longer years of menopause and more numbers of motherhood.
Objective:To study the risk factors for osteoporosis(OP)in female patients with osteoarthritis(OA).Methods:The bone mineral density(BMD) in the lumbar vertebrae(L1~4),femoral neck and total femoral area of 300 female patients with OA and 101 female healthy subjects were measured by dual energy X-ray absorptiometry.The risk factors for OP were analyzed statistically in each group.Results:The incidence of OP in the female patients with OA was significant higher than that in the healthy subjects(P<0.01).The BMD of all positions in the female patients with OA was lower than that in the healthy subjects(P<0.01).Of all the patients with OA,those who had been diagnosed as having OP had lower BMD than those who had not (P<0.01).The BMD in the menopause group with OA was lower than that in the pre-menopausal group.Of all the patients with OA,the OP group had elder ages,longer years of menopause and more numbers of motherhood.And the differences were all statistically significant(P<0.01).The probability of osteoporotic fracture in patients with OA was obviously higher than that in healthy subjects in the next 10 years(P<0.01).Conclusions:Compared with the healthy subjects,patients with OA are more easily affected by OP and osteoporotic fracture.The incidence of OP is related to several risk factors such as elder ages,longer years of menopause and more numbers of motherhood.
2016, 41(5): 583-585.
doi: 10.13898/j.cnki.issn.1000-2200.2016.05.008
Abstract:
Objective:To explore the clinical significance of metadherin(MTDH) expression in ovarian cancer.Methods:The MTDH expression in 56 patients with ovarian cancer were detected using immunohistochemistry,the related pathological data was analyzed.Results:The expression positive rate of MTDH in 56 patients was 53.6%(30/56).The expression positive rate of MTDH in stage Ⅲ/Ⅳ patients was significantly higher than that in stage Ⅰ/Ⅱ patients(P<0.01),the expression positive rate of MTDH in patients with lymph node metastasis was significantly higher than that in patients without lymph node metastasis(P<0.05),and the differences of MTDH expression in different age,tumor histology,staging and ascites were not statistically significant(P >0.05).Conclusions:The MTDH expression in ovarian cancer is high,which may play an important role in growth and development of tumor,and can guide the treatment and predict prognosis.
Objective:To explore the clinical significance of metadherin(MTDH) expression in ovarian cancer.Methods:The MTDH expression in 56 patients with ovarian cancer were detected using immunohistochemistry,the related pathological data was analyzed.Results:The expression positive rate of MTDH in 56 patients was 53.6%(30/56).The expression positive rate of MTDH in stage Ⅲ/Ⅳ patients was significantly higher than that in stage Ⅰ/Ⅱ patients(P<0.01),the expression positive rate of MTDH in patients with lymph node metastasis was significantly higher than that in patients without lymph node metastasis(P<0.05),and the differences of MTDH expression in different age,tumor histology,staging and ascites were not statistically significant(P >0.05).Conclusions:The MTDH expression in ovarian cancer is high,which may play an important role in growth and development of tumor,and can guide the treatment and predict prognosis.
2016, 41(5): 586-588.
doi: 10.13898/j.cnki.issn.1000-2200.2016.05.009
Abstract:
Objective:To measure the serum levels of insulin-like growth factor-1(IGF-1) and insulin-like growth factor binding protein-3(IGF-BP3) in patients with type 2 diabetic nephropathy,and explore its correlation with type 2 diabetic nephropathy.Methods:According to the results of the urinary albumin excretion rate(UAER),86 patients with type 2 diabetes were divided into the simple diabetes group(SDM group,33 cases),early diabetic nephropathy group(EDN group,28 cases) and clinical stage of nephropathy group(CDN group,25 cases).The levels of the IGF-1,IGF-BP3,UAER and other indicators were detected,which was used to analyze the correlations of IGF-1 and IGF-BP3 with diabetic nephropathy.Results:The serum levels of IGF-1 and IGF-BP3 and UAER in CDN group were higher than those in SDM group and CDN group(P<0.01),the serum levels of IGF-1,IGF-BP3 and UAER in CDN group were higher than those in EDN group(P<0.01).The IGF-1 was positive correlation with the creatinine,urea nitrogen,UAER and IGF-BP3,respectively(P<0.01),the IGF-1 was correlation without age and glycosylated hemoglobin(P >0.05),and was negative correlation with fasting plasma glucose(P<0.01).Conclusions:The serum levels of IGF-1 and IGF-BP3 are related to the occurrence and development of type 2 diabetic nephropathy,which can be used as one of the early diagnosis index of diabetic nephropathy.
Objective:To measure the serum levels of insulin-like growth factor-1(IGF-1) and insulin-like growth factor binding protein-3(IGF-BP3) in patients with type 2 diabetic nephropathy,and explore its correlation with type 2 diabetic nephropathy.Methods:According to the results of the urinary albumin excretion rate(UAER),86 patients with type 2 diabetes were divided into the simple diabetes group(SDM group,33 cases),early diabetic nephropathy group(EDN group,28 cases) and clinical stage of nephropathy group(CDN group,25 cases).The levels of the IGF-1,IGF-BP3,UAER and other indicators were detected,which was used to analyze the correlations of IGF-1 and IGF-BP3 with diabetic nephropathy.Results:The serum levels of IGF-1 and IGF-BP3 and UAER in CDN group were higher than those in SDM group and CDN group(P<0.01),the serum levels of IGF-1,IGF-BP3 and UAER in CDN group were higher than those in EDN group(P<0.01).The IGF-1 was positive correlation with the creatinine,urea nitrogen,UAER and IGF-BP3,respectively(P<0.01),the IGF-1 was correlation without age and glycosylated hemoglobin(P >0.05),and was negative correlation with fasting plasma glucose(P<0.01).Conclusions:The serum levels of IGF-1 and IGF-BP3 are related to the occurrence and development of type 2 diabetic nephropathy,which can be used as one of the early diagnosis index of diabetic nephropathy.
2016, 41(5): 589-591.
doi: 10.13898/j.cnki.issn.1000-2200.2016.05.010
Abstract:
Objective:To explore the application value of the level of arterial blood lactate in the evaluation of disease severity and prognosis of neonatal asphyxia.Methods:The levels of Neonatal Critical Illness Score(NCIS) and arteral blood lactate in 108 neonates with asphyxia were investigated after admission.The correlation between the score of NCIS and level of arteral blood lactate was analyzed,and the linear regression equation of which was established.The relationship between the level of arteral blood lactate and prognosis of neonatal asphyxia was observed.Results:The linear correlation analysis results showed that the lower the score was,the higher the level of arterial blood lactate was,and the relation of which was significantly negative(P<0.01).The linear regression equation showed that the concentration of arteral blood lactate was 19.403-0.177×NCIS.When the arteral blood lactate concentration was less than 3.473 mmol/L,3.473 to 7.013 mmol/L and more than 7.013 mmol/L,the incidences of severe asphyxia was 12.00%,71.93% and 100.00%,respectively,the incidences of the multiple organ injury was 0.00%,84.21% and 100.00%,respectively,and the incidences of mortality was 0.00%,1.75% and 19.23%,respectively,the differences of whose were statistically significant(P<0.01).Conclusions:The level of arterial blood lactate is a objective,sensitive and simple quantitative indicator,which can provide the reliable basis in quick and timely judging the disease severity and prognosis of neonatal asphyxia.
Objective:To explore the application value of the level of arterial blood lactate in the evaluation of disease severity and prognosis of neonatal asphyxia.Methods:The levels of Neonatal Critical Illness Score(NCIS) and arteral blood lactate in 108 neonates with asphyxia were investigated after admission.The correlation between the score of NCIS and level of arteral blood lactate was analyzed,and the linear regression equation of which was established.The relationship between the level of arteral blood lactate and prognosis of neonatal asphyxia was observed.Results:The linear correlation analysis results showed that the lower the score was,the higher the level of arterial blood lactate was,and the relation of which was significantly negative(P<0.01).The linear regression equation showed that the concentration of arteral blood lactate was 19.403-0.177×NCIS.When the arteral blood lactate concentration was less than 3.473 mmol/L,3.473 to 7.013 mmol/L and more than 7.013 mmol/L,the incidences of severe asphyxia was 12.00%,71.93% and 100.00%,respectively,the incidences of the multiple organ injury was 0.00%,84.21% and 100.00%,respectively,and the incidences of mortality was 0.00%,1.75% and 19.23%,respectively,the differences of whose were statistically significant(P<0.01).Conclusions:The level of arterial blood lactate is a objective,sensitive and simple quantitative indicator,which can provide the reliable basis in quick and timely judging the disease severity and prognosis of neonatal asphyxia.
2016, 41(5): 592-596.
doi: 10.13898/j.cnki.issn.1000-2200.2016.05.011
Abstract:
Objective:To observe the effects of high intensity focused ultrasound and low temperature radiofrequency ablation under nasal endoscope in the treatment of allergic rhinitis.Methods:One hundred and seventy-nine patients with allergic rhinitis were divided into the focused ultrasound group(FU group,84 cases) and radiofrequency ablation group(RFA group,95 cases).The symptoms and signs in all patients were recorded and scored before and after treatment,and the therapeutic effects between two groups were analyzed.Results:The score of the symptoms and signs in FU group before treatment(10.84±2.26) was significantly higher than that after 12 months of treatment(4.65±1.76)(P<0.01).The score of the symptoms and signs in RFA group before treatment(10.02±2.05) was significantly higher than that after 12 months of treatment(5.32±1.37)(P<0.01).Two groups were followed up for 1 year.The total effective rates in FU and RFA group were 86.9% and 73.7%,respectively,the difference of which was statistically significant(P<0.05).Conclusions:The high intensity focused ultrasound and radiofrequency ablation are the effective physical methods in treating allergic rhinitis,especially within 1 year.The treatment of allergic rhinitis with focused ultrasound is less trauma,can be repeated,and its curative effect is more durable after 1 year.
Objective:To observe the effects of high intensity focused ultrasound and low temperature radiofrequency ablation under nasal endoscope in the treatment of allergic rhinitis.Methods:One hundred and seventy-nine patients with allergic rhinitis were divided into the focused ultrasound group(FU group,84 cases) and radiofrequency ablation group(RFA group,95 cases).The symptoms and signs in all patients were recorded and scored before and after treatment,and the therapeutic effects between two groups were analyzed.Results:The score of the symptoms and signs in FU group before treatment(10.84±2.26) was significantly higher than that after 12 months of treatment(4.65±1.76)(P<0.01).The score of the symptoms and signs in RFA group before treatment(10.02±2.05) was significantly higher than that after 12 months of treatment(5.32±1.37)(P<0.01).Two groups were followed up for 1 year.The total effective rates in FU and RFA group were 86.9% and 73.7%,respectively,the difference of which was statistically significant(P<0.05).Conclusions:The high intensity focused ultrasound and radiofrequency ablation are the effective physical methods in treating allergic rhinitis,especially within 1 year.The treatment of allergic rhinitis with focused ultrasound is less trauma,can be repeated,and its curative effect is more durable after 1 year.
2016, 41(5): 595-597.
doi: 10.13898/j.cnki.issn.1000-2200.2016.05.012
Abstract:
Objective:To explore the measure to avoid the missed diagnosis of prostate carcinoma in patients with normal level of prostate specific antigen(PSA).Methods:Two hundred and three prostate hyperplasia patients with normal PSA level were treated with transurethral resection of the prostate,and the clinical data of 6 cases with prostate carcinoma diagnosed by pathological examination were retrospectively analyzed.Results:The signs of prostate carcinoma in 6 cases with prostate carcinoma were not found by the conventional ultrasonography examination and anus digital,and the 6 patients were the first visit to hospitalization.Among 6 cases,1 case was undifferentiation,1 case was middle differentiation with severe condition of prostate carcinoma,the disease developed rapidly,and 2 cases died in a short period of time.The rest 4 patients were highly differentiation prostate carcinoma,and still live now.Conclusions:The normal level of prostate specific antigen can be found in the early incidental prostate carcinoma and progressive prostate carcinoma,which can lead to the missed diagnosis.The application of ultrasound combined with nuclear magnetic resonance,especially transrectal ultrasonography of prostate and prostate specific antigen rate,should be considered.The prostatic puncture in suspected patient should be performed to improve the early diagnosis rate of prostate carcinoma.
Objective:To explore the measure to avoid the missed diagnosis of prostate carcinoma in patients with normal level of prostate specific antigen(PSA).Methods:Two hundred and three prostate hyperplasia patients with normal PSA level were treated with transurethral resection of the prostate,and the clinical data of 6 cases with prostate carcinoma diagnosed by pathological examination were retrospectively analyzed.Results:The signs of prostate carcinoma in 6 cases with prostate carcinoma were not found by the conventional ultrasonography examination and anus digital,and the 6 patients were the first visit to hospitalization.Among 6 cases,1 case was undifferentiation,1 case was middle differentiation with severe condition of prostate carcinoma,the disease developed rapidly,and 2 cases died in a short period of time.The rest 4 patients were highly differentiation prostate carcinoma,and still live now.Conclusions:The normal level of prostate specific antigen can be found in the early incidental prostate carcinoma and progressive prostate carcinoma,which can lead to the missed diagnosis.The application of ultrasound combined with nuclear magnetic resonance,especially transrectal ultrasonography of prostate and prostate specific antigen rate,should be considered.The prostatic puncture in suspected patient should be performed to improve the early diagnosis rate of prostate carcinoma.
2016, 41(5): 598-601.
doi: 10.13898/j.cnki.issn.1000-2200.2016.05.013
Abstract:
Objective:To investigate the clinical features and diagnosis of tsutsugamushi to provide the basis of treatment.Methods:The clinical data of 17 patients with tsutsugamushi were from October to November 2012 retrospectively analyzed.Results:Seventeen patients(including 16 farmers and 1 worker) had a history of contact with grassland and woodland.The varying degrees fever in 17 cases(100.00%),skin ulcers or eschar in 9 cases(52.94%),skin rash in 12 cases(70.59),liver injury in 14 cases(82.35%),renal injury in 8 cases(47.06%),splenomegaly in 2 cases(11.76%) and lymphadenovarix in 2 cases(11.76%) were found.The misdiagnosis rate was 47.06%.All patients cured after the treatment with azithromycin and/or levofloxacin.Conclusions:The clinical manifestations of tsutsugamushi is complex and diverse,and its misdiagnosis rate is high.Macrolides and quinolones are the most effective drugs in the treatment tsutsugamushi.The epidemic focus is founded in northern Anhui province.
Objective:To investigate the clinical features and diagnosis of tsutsugamushi to provide the basis of treatment.Methods:The clinical data of 17 patients with tsutsugamushi were from October to November 2012 retrospectively analyzed.Results:Seventeen patients(including 16 farmers and 1 worker) had a history of contact with grassland and woodland.The varying degrees fever in 17 cases(100.00%),skin ulcers or eschar in 9 cases(52.94%),skin rash in 12 cases(70.59),liver injury in 14 cases(82.35%),renal injury in 8 cases(47.06%),splenomegaly in 2 cases(11.76%) and lymphadenovarix in 2 cases(11.76%) were found.The misdiagnosis rate was 47.06%.All patients cured after the treatment with azithromycin and/or levofloxacin.Conclusions:The clinical manifestations of tsutsugamushi is complex and diverse,and its misdiagnosis rate is high.Macrolides and quinolones are the most effective drugs in the treatment tsutsugamushi.The epidemic focus is founded in northern Anhui province.
2016, 41(5): 600-602.
doi: 10.13898/j.cnki.issn.1000-2200.2016.05.014
Abstract:
Objective:To investigate the surgical method and clinical effects of the free dorsal interosseous artery perforator flap on repairing the middle and small area skin defect of hand.Methods:The free dorsal interosseous artery perforator flap was obstained,the area of which was 2.0 cm×3.6 cm to 4.0 cm×8.0 cm.The microvascular anastomosis was implemented by end-to-end or end-to-side,the donor position was directly sutured.Results:All 19 flaps survived.The patients were followed up for 6 to 12 months.The texture of flap and hand function were good,only the linear scar was found in donor position.Conclusions:The dorsal interosseous artery perforator flap has stably anatomical structure,fine texture and suitable thickness,which is suitable for the repair of the middle and small area skin defect of hand.
Objective:To investigate the surgical method and clinical effects of the free dorsal interosseous artery perforator flap on repairing the middle and small area skin defect of hand.Methods:The free dorsal interosseous artery perforator flap was obstained,the area of which was 2.0 cm×3.6 cm to 4.0 cm×8.0 cm.The microvascular anastomosis was implemented by end-to-end or end-to-side,the donor position was directly sutured.Results:All 19 flaps survived.The patients were followed up for 6 to 12 months.The texture of flap and hand function were good,only the linear scar was found in donor position.Conclusions:The dorsal interosseous artery perforator flap has stably anatomical structure,fine texture and suitable thickness,which is suitable for the repair of the middle and small area skin defect of hand.
2016, 41(5): 603-604,607.
doi: 10.13898/j.cnki.issn.1000-2200.2016.05.015
Abstract:
Objective:To explore the effects of the old and new labor standards on delivery outcome.Methods:One hundred and five primipara with the first or second abnormal delivery according to the old Friedman partogram were randomly divided into the observation group(53 cases) and control group(52 cases).The control group were continually treated with the old labor standards,the observation group were treated with the new labor standards(2014).The labor intervention,delivery mode,postpartum hemorrhage and neonatal outcome between two groups were compared.Results:The rates of cesarean section and natural childbirth in observation group were significantly lower and higher than that in control group,respectively(P<0.01).The differences of the rates of intervention,postpartum hemorrhage and neonatal asphyxia between two groups were not statistically significant(P >0.05).Conclusions:The new labor standards treatment can improve the natural birth rate,significantly reduce the cesarean section rate and do not increase the complication.
Objective:To explore the effects of the old and new labor standards on delivery outcome.Methods:One hundred and five primipara with the first or second abnormal delivery according to the old Friedman partogram were randomly divided into the observation group(53 cases) and control group(52 cases).The control group were continually treated with the old labor standards,the observation group were treated with the new labor standards(2014).The labor intervention,delivery mode,postpartum hemorrhage and neonatal outcome between two groups were compared.Results:The rates of cesarean section and natural childbirth in observation group were significantly lower and higher than that in control group,respectively(P<0.01).The differences of the rates of intervention,postpartum hemorrhage and neonatal asphyxia between two groups were not statistically significant(P >0.05).Conclusions:The new labor standards treatment can improve the natural birth rate,significantly reduce the cesarean section rate and do not increase the complication.
2016, 41(5): 605-607.
doi: 10.13898/j.cnki.issn.1000-2200.2016.05.016
Abstract:
Objective:To observe the influence of different extubation on the postoperative cognitive function in elderly patients with general anaesthesia.Methods:Eighty elderly patients scheduled by operation under general anaesthesia were randomly divided into the remifentanil-dexmedetomidine group(group R) and control group(40 cases each group).Two groups were induced using fentanyl- propofol-rocurunium bromide scheme,and maintained anaesthesia using propofol-remifentanil-cisatracuriumbesylate scheme.After operation,the group R patients were injected with 0.03 μg·kg-1·min-1 of remifentainil and 0.01 μg·kg-1·min-1 of dexmedetomidine until postextubation 5 minutes.The control group were injected with the same dose of 0.9% sodium chloride until postextubation 5 minutes.The congnitive functions of all patients at preoperation,and postoperative 1 and 3 days were assessed using the Mini-Mental State Examination,and the levels of blood glucose and blood lactic acid in two groups were detected at preoperation,intubation and extubation.Results:The difference of the congnitive function between two groups before operation was not statistically significant(P >0.05),and the scores of congnitive function in group R at postoperative 1 and 3 days were significantly higher than that in control group(P<0.01).The differences of the congnitive function scores in group R between preoperation,postoperative 1 and 3 days were not statistically significant(P >0.05),and the scores of congnitive function at postoperative 1 and 3 days were significantly lower than that before operation in control group(P<0.01).The differences of the blood glucose level between preoperation and intubation,and blood lactic acid level between intubation and extubation in two groups were not statistically significant(P >0.05).The differences of the levels of blood glucose and blood lactic acid between preoperation,intubation and extubation in group R were not statistically significant(P >0.05).The level of blood glucose in control group at extubation was significantly higher than that in control group at preoperation and intubation,and group R(P<0.01).The differences of the blood lactic acid levels at preoperation,intubation and extubation in control group were not statistically significant(P >0.05).Conclusions:The application of remifentainil and dexmedetomidine during extubation can decrease the influence of the postoperative cognitive function in elderly patients.
Objective:To observe the influence of different extubation on the postoperative cognitive function in elderly patients with general anaesthesia.Methods:Eighty elderly patients scheduled by operation under general anaesthesia were randomly divided into the remifentanil-dexmedetomidine group(group R) and control group(40 cases each group).Two groups were induced using fentanyl- propofol-rocurunium bromide scheme,and maintained anaesthesia using propofol-remifentanil-cisatracuriumbesylate scheme.After operation,the group R patients were injected with 0.03 μg·kg-1·min-1 of remifentainil and 0.01 μg·kg-1·min-1 of dexmedetomidine until postextubation 5 minutes.The control group were injected with the same dose of 0.9% sodium chloride until postextubation 5 minutes.The congnitive functions of all patients at preoperation,and postoperative 1 and 3 days were assessed using the Mini-Mental State Examination,and the levels of blood glucose and blood lactic acid in two groups were detected at preoperation,intubation and extubation.Results:The difference of the congnitive function between two groups before operation was not statistically significant(P >0.05),and the scores of congnitive function in group R at postoperative 1 and 3 days were significantly higher than that in control group(P<0.01).The differences of the congnitive function scores in group R between preoperation,postoperative 1 and 3 days were not statistically significant(P >0.05),and the scores of congnitive function at postoperative 1 and 3 days were significantly lower than that before operation in control group(P<0.01).The differences of the blood glucose level between preoperation and intubation,and blood lactic acid level between intubation and extubation in two groups were not statistically significant(P >0.05).The differences of the levels of blood glucose and blood lactic acid between preoperation,intubation and extubation in group R were not statistically significant(P >0.05).The level of blood glucose in control group at extubation was significantly higher than that in control group at preoperation and intubation,and group R(P<0.01).The differences of the blood lactic acid levels at preoperation,intubation and extubation in control group were not statistically significant(P >0.05).Conclusions:The application of remifentainil and dexmedetomidine during extubation can decrease the influence of the postoperative cognitive function in elderly patients.
2016, 41(5): 608-611.
doi: 10.13898/j.cnki.issn.1000-2200.2016.05.017
Abstract:
Objective:To evaluate the clinical efficacy of compound glycyrrhizin combined with minoxidil and desonide in the treatment of alopecia areata.Methods:Eighty-five patients with alopecia areata were randomly divided into the observation group(45 cases) and control group(40 cases).All patients were treated with minoxidil liniment combined with desonide cream by external use,twice a day.The observation group were additionally treated with compound glycyrrhizin by oral.The treatment course was 3 months,the clinical efficacy was evaluated after treatment.Results:The effective rate in observation group(88.89%) was significantly better than those in control group(67.5%)(P<0.01).Conclusions:The treatment of alopecia areata with compound glycyrrhizin combined with minoxidil liniment and desonide cream is safe and effective,which is worthy of clinical popular application.
Objective:To evaluate the clinical efficacy of compound glycyrrhizin combined with minoxidil and desonide in the treatment of alopecia areata.Methods:Eighty-five patients with alopecia areata were randomly divided into the observation group(45 cases) and control group(40 cases).All patients were treated with minoxidil liniment combined with desonide cream by external use,twice a day.The observation group were additionally treated with compound glycyrrhizin by oral.The treatment course was 3 months,the clinical efficacy was evaluated after treatment.Results:The effective rate in observation group(88.89%) was significantly better than those in control group(67.5%)(P<0.01).Conclusions:The treatment of alopecia areata with compound glycyrrhizin combined with minoxidil liniment and desonide cream is safe and effective,which is worthy of clinical popular application.
2016, 41(5): 610-612.
doi: 10.13898/j.cnki.issn.1000-2200.2016.05.018
Abstract:
Objective:To observe the effects of MOTOmed system treatment on improving the limb motor function and life skills in patients with cerebral infarction.Methods:Sixty-one patients with acute cerebral infarction complicated with hemiplegia were randomly divided into the study group(30 cases) and control group(31 cases).The control group were treated with only conventional drug and rehabilitation,the study group were treated with the repetitive exercise of MOTOmed letto2 and viva 2 based on the control group.The symptoms improvement in two groups were evaluated using Fugl-Meyer(FMA) scale,Barthel's ADL index,improved spasticity rating scale(Asworth) and HAMD before and after treatment.Results:After 8 weeks of treatment,the total effective rates of study group and control group were 90.65% and 61.33%,respectively,the difference of which was statistically significant(P<0.01).After treatment,the scores of FMA and ADL in study group were higher than those in control group(P<0.01),the score of Asworth in study group was lower than that in control group(P<0.05).Compared with that before treatment,the scores of Asworth and HAMD decreased after treatment(P<0.05 and P<0.01),which in study group was better than that in control group(P<0.01).Conclusions:MOTOmed system can significantly improve the limb motor function,life skills and depression symptom in patients with cerebral infarction complicated with hemiplegia.
Objective:To observe the effects of MOTOmed system treatment on improving the limb motor function and life skills in patients with cerebral infarction.Methods:Sixty-one patients with acute cerebral infarction complicated with hemiplegia were randomly divided into the study group(30 cases) and control group(31 cases).The control group were treated with only conventional drug and rehabilitation,the study group were treated with the repetitive exercise of MOTOmed letto2 and viva 2 based on the control group.The symptoms improvement in two groups were evaluated using Fugl-Meyer(FMA) scale,Barthel's ADL index,improved spasticity rating scale(Asworth) and HAMD before and after treatment.Results:After 8 weeks of treatment,the total effective rates of study group and control group were 90.65% and 61.33%,respectively,the difference of which was statistically significant(P<0.01).After treatment,the scores of FMA and ADL in study group were higher than those in control group(P<0.01),the score of Asworth in study group was lower than that in control group(P<0.05).Compared with that before treatment,the scores of Asworth and HAMD decreased after treatment(P<0.05 and P<0.01),which in study group was better than that in control group(P<0.01).Conclusions:MOTOmed system can significantly improve the limb motor function,life skills and depression symptom in patients with cerebral infarction complicated with hemiplegia.
2016, 41(5): 613-615.
doi: 10.13898/j.cnki.issn.1000-2200.2016.05.019
Abstract:
Objective:To explore the clinicopathological characteristics,diagnosis,differential diagnosis and biological behavior of gastric glomus tumor.Methods:The histological manifestations and immunohistochemical results in 3 gastric glomus tumors were analyzed,and the relevant literature was reviewed.Results:All cases were preoperatively diagnosed as gastrointestinal stromal tumor,and the postoperative pathological diagnosis of which was gastric glomus tumor.Tumor tissue was lobulated node,and separated and enveloped by smooth muscle cells.The tumor cells were uniform-sized,round or oval,arranging around the blood vessels.Tumor nuclei were round with visible nucleoli,no nuclear atypia and rare mitoses.The immunohistochemical staining showed that the vimentin,SMA and calponin were positive,and CgA,NSE,AE1/AE3,CD117,CD34,LCA,desmin,CD99 and S-100 were negative.The recurrence in 3 cases of gastric glomus tumor were not found during the 2 to 4 years of following up.Conclusions:Gastric glomus tumor is rare,which has the distinct morphological and immunohistochemical features,can be easily misdiagnosed.
Objective:To explore the clinicopathological characteristics,diagnosis,differential diagnosis and biological behavior of gastric glomus tumor.Methods:The histological manifestations and immunohistochemical results in 3 gastric glomus tumors were analyzed,and the relevant literature was reviewed.Results:All cases were preoperatively diagnosed as gastrointestinal stromal tumor,and the postoperative pathological diagnosis of which was gastric glomus tumor.Tumor tissue was lobulated node,and separated and enveloped by smooth muscle cells.The tumor cells were uniform-sized,round or oval,arranging around the blood vessels.Tumor nuclei were round with visible nucleoli,no nuclear atypia and rare mitoses.The immunohistochemical staining showed that the vimentin,SMA and calponin were positive,and CgA,NSE,AE1/AE3,CD117,CD34,LCA,desmin,CD99 and S-100 were negative.The recurrence in 3 cases of gastric glomus tumor were not found during the 2 to 4 years of following up.Conclusions:Gastric glomus tumor is rare,which has the distinct morphological and immunohistochemical features,can be easily misdiagnosed.
2016, 41(5): 616-618.
doi: 10.13898/j.cnki.issn.1000-2200.2016.05.020
Abstract:
Objective:To compare the clinical effects of different doses of dexmedetomidine on the percutaneous coronary intervention(PCI) in patients with acute coronary syndrome.Methods:A total of 80 acute coronary syndrome patients treated with PCI were randomly divided into the high dose group and low dose group(40 cases each group).The low dose group and high dose group were sedated with 0.3 μg/kg and 0.6 μg/kg of dexmedetomidine,respectively.The perioperative heart rate,blood pressure,postoperative stress index and adverse reaction between two groups were compared.Results:The systolic blood pressure,diastolic blood pressure and heart rate in high dose group were significantly lower than those in low dose group at T1 to T5 after the start of operation(P<0.05 to P<0.01).The levels of cTnI,CK-MB,BNP,hs-CRP,IL-6 and TNF-α in high dose group were significantly lower than those in low dose group after 2 days of operation(P<0.01).The difference of the adverse reaction in two groups was not statistically significant(P >0.05).Conclusions:The application of 0.6 μg/kg of dexmedetomidine in acute coronary syndrome patients treated with PCI has good sedation effects and low stress response,which is worthy of clinical application.
Objective:To compare the clinical effects of different doses of dexmedetomidine on the percutaneous coronary intervention(PCI) in patients with acute coronary syndrome.Methods:A total of 80 acute coronary syndrome patients treated with PCI were randomly divided into the high dose group and low dose group(40 cases each group).The low dose group and high dose group were sedated with 0.3 μg/kg and 0.6 μg/kg of dexmedetomidine,respectively.The perioperative heart rate,blood pressure,postoperative stress index and adverse reaction between two groups were compared.Results:The systolic blood pressure,diastolic blood pressure and heart rate in high dose group were significantly lower than those in low dose group at T1 to T5 after the start of operation(P<0.05 to P<0.01).The levels of cTnI,CK-MB,BNP,hs-CRP,IL-6 and TNF-α in high dose group were significantly lower than those in low dose group after 2 days of operation(P<0.01).The difference of the adverse reaction in two groups was not statistically significant(P >0.05).Conclusions:The application of 0.6 μg/kg of dexmedetomidine in acute coronary syndrome patients treated with PCI has good sedation effects and low stress response,which is worthy of clinical application.
2016, 41(5): 619-622.
doi: 10.13898/j.cnki.issn.1000-2200.2016.05.021
Abstract:
Objective:To evaluate the clinical effects of the electronic fexible ureteroscopy combined with holmium laser lithotripsy(FURL) in the tretment of kidney and upper ureteral calculi.Methods:The clinical data of 42 kidney and upper ureteral calculi patients treated with FURL were retrospectively analyzed.The operation time,stone-free rate(SFR),and complications were evaluated.Results:A total of 42 patients were treated with FURL.The mean operative duration and first stage SFR in 27 cases with the diameter of calculi ≤2 cm were (73.9±21.2)min and 100%,respectively.The mean operative duration and first stage SFR in 11 cases with the diameter of calculi >2 cm and ≤3 cm were (94.5±29.1)min and 81.8%,respectively.The mean operative duration and first stage SFR in 4 cases with the diameter of calculi >3 cm were (120±36.7)min and 25.0%,respectively.The difference of the first stage SFR between the patients with the diameter of calculi ≤2 cm,and >2 cm and ≤3 cm was not statistically significant(P >0.05),while the first stage SFRs of whose were higher than that in patients with the diameter of calculi >3 cm(P<0.01 and P<0.05).The number of fever patients in positive urine leukocyte group were higher than that in negative urine leukocyte group.The fever in 8 patients and no other serious complications were found.Conclusions:The treatment of kidney and upper ureteral calculi with the diameter ≤2 cm with FURL is minimally invasive,safe and effective.
Objective:To evaluate the clinical effects of the electronic fexible ureteroscopy combined with holmium laser lithotripsy(FURL) in the tretment of kidney and upper ureteral calculi.Methods:The clinical data of 42 kidney and upper ureteral calculi patients treated with FURL were retrospectively analyzed.The operation time,stone-free rate(SFR),and complications were evaluated.Results:A total of 42 patients were treated with FURL.The mean operative duration and first stage SFR in 27 cases with the diameter of calculi ≤2 cm were (73.9±21.2)min and 100%,respectively.The mean operative duration and first stage SFR in 11 cases with the diameter of calculi >2 cm and ≤3 cm were (94.5±29.1)min and 81.8%,respectively.The mean operative duration and first stage SFR in 4 cases with the diameter of calculi >3 cm were (120±36.7)min and 25.0%,respectively.The difference of the first stage SFR between the patients with the diameter of calculi ≤2 cm,and >2 cm and ≤3 cm was not statistically significant(P >0.05),while the first stage SFRs of whose were higher than that in patients with the diameter of calculi >3 cm(P<0.01 and P<0.05).The number of fever patients in positive urine leukocyte group were higher than that in negative urine leukocyte group.The fever in 8 patients and no other serious complications were found.Conclusions:The treatment of kidney and upper ureteral calculi with the diameter ≤2 cm with FURL is minimally invasive,safe and effective.
2016, 41(5): 623-625.
doi: 10.13898/j.cnki.issn.1000-2200.2016.05.022
Abstract:
Objective:To investigate the relationships between the levels of homocysteine(Hcy),hypersensitive C reactive protein(hs-CRP),low density lipoprotein(LDL-C),triglyceride(TG) and total cholesterol(TC) and acute cerebral infarction(ACI).Methods:Sixty-one patients with ACI and 32 patients without cerebrovascular disease were divided into the ACI group and control group.The levels of Hcy,hs-CRP,LDL-C,TG and TC in two groups were compared.The correlation of the levels of Hcy,hs-CRP,LDL-C,TG and TC with the occurrence of acute cerebral infarction were analyzed.Results:Compared with the control group,the levels of serum Hcy,hs-CRP,LDL-C,TG and TC in ACI group increased(P<0.05 to and P<0.01).The obvious correlation of Hcy with hs-CRP,TG,LDL-C and TC did not found(P >0.05).Conclusions:The levels of the serum Hcy,hs-CRP,LDL-C,TG and TC in patients with acute cerebral infarction increased significantly,whose were the important risk factors of the occurence of cerebral infarction.
Objective:To investigate the relationships between the levels of homocysteine(Hcy),hypersensitive C reactive protein(hs-CRP),low density lipoprotein(LDL-C),triglyceride(TG) and total cholesterol(TC) and acute cerebral infarction(ACI).Methods:Sixty-one patients with ACI and 32 patients without cerebrovascular disease were divided into the ACI group and control group.The levels of Hcy,hs-CRP,LDL-C,TG and TC in two groups were compared.The correlation of the levels of Hcy,hs-CRP,LDL-C,TG and TC with the occurrence of acute cerebral infarction were analyzed.Results:Compared with the control group,the levels of serum Hcy,hs-CRP,LDL-C,TG and TC in ACI group increased(P<0.05 to and P<0.01).The obvious correlation of Hcy with hs-CRP,TG,LDL-C and TC did not found(P >0.05).Conclusions:The levels of the serum Hcy,hs-CRP,LDL-C,TG and TC in patients with acute cerebral infarction increased significantly,whose were the important risk factors of the occurence of cerebral infarction.
2016, 41(5): 626-628.
doi: 10.13898/j.cnki.issn.1000-2200.2016.05.023
Abstract:
Objective:To analyze the serum levels of vascular endothelial growth factor(VEGF),osteoprotegerin(OPN) and tumor markers in patients with different outcomes after transcatheter arterial immune chemoembolization(TAICE),and its significance in evaluating postoperative effects.Methods:The clinical efficacy,and the levels of VEGF,OPN and tumor marker in 41 patients with moderate or advanced liver cancer were evaluated after TAICE.Results:The complete remission(CR) in 4 cases(9.8%),partial remission(PR) in 31 cases (75.6%),SD in 4 cases(9.8%) and PD in 2 cases(4.9%) were identified after operation,the total effective rate was 85.4%.The levels of OPN and VEGF in PR patients were significantly higher than those in CR patients(P<0.01).Compared with the CR and PR patients,the levels of OPN and VEGF in SD patients increased significantly(P<0.01).Compared with the CR,PR and SD patients,the levels of OPN and VEGF in PD patients increased significantly(P<0.01).Compared with the CR patients,the levels of AFP,CEA and AFU in PR patients increased significantly(P<0.05 to P<0.01).Compared with the CR and PR patients,the levels of AFP and AFU in SD patients increased significantly(P<0.01).Compared with the CR patients,the level of CEA in SD patients increased significantly(P<0.05).Compared with the CR,PR and SD patients,the levels of AFP,CEA and AFU in PD patients increased significantly(P<0.01).Conclusions:The treatment of hepatocellular carcinoma with TAICE has better clinical effects.The VEGF and OPN involve in development of hepatocellular carcinoma,which are the important indicators in evaluating the clinical efficacy.
Objective:To analyze the serum levels of vascular endothelial growth factor(VEGF),osteoprotegerin(OPN) and tumor markers in patients with different outcomes after transcatheter arterial immune chemoembolization(TAICE),and its significance in evaluating postoperative effects.Methods:The clinical efficacy,and the levels of VEGF,OPN and tumor marker in 41 patients with moderate or advanced liver cancer were evaluated after TAICE.Results:The complete remission(CR) in 4 cases(9.8%),partial remission(PR) in 31 cases (75.6%),SD in 4 cases(9.8%) and PD in 2 cases(4.9%) were identified after operation,the total effective rate was 85.4%.The levels of OPN and VEGF in PR patients were significantly higher than those in CR patients(P<0.01).Compared with the CR and PR patients,the levels of OPN and VEGF in SD patients increased significantly(P<0.01).Compared with the CR,PR and SD patients,the levels of OPN and VEGF in PD patients increased significantly(P<0.01).Compared with the CR patients,the levels of AFP,CEA and AFU in PR patients increased significantly(P<0.05 to P<0.01).Compared with the CR and PR patients,the levels of AFP and AFU in SD patients increased significantly(P<0.01).Compared with the CR patients,the level of CEA in SD patients increased significantly(P<0.05).Compared with the CR,PR and SD patients,the levels of AFP,CEA and AFU in PD patients increased significantly(P<0.01).Conclusions:The treatment of hepatocellular carcinoma with TAICE has better clinical effects.The VEGF and OPN involve in development of hepatocellular carcinoma,which are the important indicators in evaluating the clinical efficacy.
2016, 41(5): 640-642.
doi: 10.13898/j.cnki.issn.1000-2200.2016.05.029
Abstract:
Objective:To explore the clinical significance of "alarm symptoms" in the early detection of cancer in elderly community population.Methods:According the case-control study,the “Alarm symptoms"(including anemia,weight loss and swallow) in 50 community elderly population were analyzed using univariate method.Results:The early “alarm symptoms" showed that the incidence rates of anemia,body weight loss,dysphagia and lower gastrointestinal hemorrhage in case group were higher than those in control group(P<0.05 to P<0.01).The comparative analysais of “Alarm symptoms" in gastric cancer and colorectal cancer showed that the incidence rates of anemia,body weight loss,dysphagia and lower gastrointestinal hemorrhage in case group were higher than those in control group(P<0.05 to P<0.01).Conclusions:The early detection of “alarm symptoms" has a certain significance in the diagnosis of tumor.The early evaluation of the “alarm symptoms" can help to the early detection and diagnosis of malignancy.
Objective:To explore the clinical significance of "alarm symptoms" in the early detection of cancer in elderly community population.Methods:According the case-control study,the “Alarm symptoms"(including anemia,weight loss and swallow) in 50 community elderly population were analyzed using univariate method.Results:The early “alarm symptoms" showed that the incidence rates of anemia,body weight loss,dysphagia and lower gastrointestinal hemorrhage in case group were higher than those in control group(P<0.05 to P<0.01).The comparative analysais of “Alarm symptoms" in gastric cancer and colorectal cancer showed that the incidence rates of anemia,body weight loss,dysphagia and lower gastrointestinal hemorrhage in case group were higher than those in control group(P<0.05 to P<0.01).Conclusions:The early detection of “alarm symptoms" has a certain significance in the diagnosis of tumor.The early evaluation of the “alarm symptoms" can help to the early detection and diagnosis of malignancy.
2016, 41(5): 643-645.
doi: 10.13898/j.cnki.issn.1000-2200.2016.05.030
Abstract:
Objective:To investigate the relationship between fluoride content and its related factors and neonatal congenital heart diseases(CHD) for finding the etiology of neonatal congenital heart diseases,and provide new idea in the prevention of neonatal congenital heart diseases.Methods:A case-control study of the 1:1 of case group and control group was designed.Each factor was analyzed using the single factor logistics regression model,the suspicious factor was analyzed using multivariate logistic regression,and the relationship between these factors and CHD was investigated.Results:The urine fluoride content in case group was significantly higher than that in control group(P<0.01),the septal defect and artery malformations were the majority type of neonatal CHD.The OR values of urine fluoride content,cooking and exposure to chemical during pregnancy were more than 1,and the OR value of drinking dairy products during pregnancy was less than 1,which were statistically significant(P<0.05 to P<0.01).Conclusions:The urine fluoride content,cooking and exposure to chemical during pregnancy are the risk factors of the occurrence of CHD.Drinking dairy product during pregnancy is protective factor of CHD.
Objective:To investigate the relationship between fluoride content and its related factors and neonatal congenital heart diseases(CHD) for finding the etiology of neonatal congenital heart diseases,and provide new idea in the prevention of neonatal congenital heart diseases.Methods:A case-control study of the 1:1 of case group and control group was designed.Each factor was analyzed using the single factor logistics regression model,the suspicious factor was analyzed using multivariate logistic regression,and the relationship between these factors and CHD was investigated.Results:The urine fluoride content in case group was significantly higher than that in control group(P<0.01),the septal defect and artery malformations were the majority type of neonatal CHD.The OR values of urine fluoride content,cooking and exposure to chemical during pregnancy were more than 1,and the OR value of drinking dairy products during pregnancy was less than 1,which were statistically significant(P<0.05 to P<0.01).Conclusions:The urine fluoride content,cooking and exposure to chemical during pregnancy are the risk factors of the occurrence of CHD.Drinking dairy product during pregnancy is protective factor of CHD.
2016, 41(5): 646-649.
doi: 10.13898/j.cnki.issn.1000-2200.2016.05.031
Abstract:
Objective:To explore the value of dynamic scanning with 64 slice spiral CT scan in the diagnosis of the subtype of renal cell carcinoma(RCC),and improve its diagnostic accuracy.Methods:Twenty-two patients with RCC diagnosed by pathology(including 11 cases of clear cell RCC,4 cases of papillary RCC and 7 cases of chromophobic cell RCC) were treated with dynamic enhancement scanning of 64 slice spiral CT.The tumor diameter,enhancement degree and mode were analyzed by CT imaging.Results:The differences of the CT value of plain scan between the papillary RCC,clear cell RCC and chromophobic cell RCC were not statistically significant(P >0.05).The CT value in clear cell RCC during the corticomedullary phase,parenchymal phase and excrete phase were significantly higher than those in papillary RCC and chromophobic cell RCC(P<0.01).The differences of the CT value between papillary RCC and chromophobic cell RCC during the corticomedullary phase,parenchymal phase and excrete phase were not statistically significant(P >0.05).Conclusions:The enhance degree of different hypotype RCC has a certain diagnosis and differential diagnosis value in hypotype of RCC.
Objective:To explore the value of dynamic scanning with 64 slice spiral CT scan in the diagnosis of the subtype of renal cell carcinoma(RCC),and improve its diagnostic accuracy.Methods:Twenty-two patients with RCC diagnosed by pathology(including 11 cases of clear cell RCC,4 cases of papillary RCC and 7 cases of chromophobic cell RCC) were treated with dynamic enhancement scanning of 64 slice spiral CT.The tumor diameter,enhancement degree and mode were analyzed by CT imaging.Results:The differences of the CT value of plain scan between the papillary RCC,clear cell RCC and chromophobic cell RCC were not statistically significant(P >0.05).The CT value in clear cell RCC during the corticomedullary phase,parenchymal phase and excrete phase were significantly higher than those in papillary RCC and chromophobic cell RCC(P<0.01).The differences of the CT value between papillary RCC and chromophobic cell RCC during the corticomedullary phase,parenchymal phase and excrete phase were not statistically significant(P >0.05).Conclusions:The enhance degree of different hypotype RCC has a certain diagnosis and differential diagnosis value in hypotype of RCC.
2016, 41(5): 649-651.
doi: 10.13898/j.cnki.issn.1000-2200.2016.05.032
Abstract:
Objective:To investigate the diagnostic value of the three phases spiral CT scan manifestation and its value in CT staging in clear cell renal carcinoma.Methods:The images of three phases CT scan in 14 patients with clear cell renal carcinoma confirmed by surgery pathology were analyzed.Results:CT scan mixed density in 12 cases and isodensity in 2 cases were found.The improved peak of enhanced scan in 2 cases and 14 cases were 80 to 94 and more than 105 Hu,respectively.Early intensive degree of corticomedullary was significantly higher than that in renal parenchyma(P<0.01).Compared with the pathological staging,the accuracy of CT staging was high.Conclusions:Three phases spiral CT scan can clearly diagnose the clear cell renal carcinoma,which has certain guiding significance in formulating the preoperative scheme.
Objective:To investigate the diagnostic value of the three phases spiral CT scan manifestation and its value in CT staging in clear cell renal carcinoma.Methods:The images of three phases CT scan in 14 patients with clear cell renal carcinoma confirmed by surgery pathology were analyzed.Results:CT scan mixed density in 12 cases and isodensity in 2 cases were found.The improved peak of enhanced scan in 2 cases and 14 cases were 80 to 94 and more than 105 Hu,respectively.Early intensive degree of corticomedullary was significantly higher than that in renal parenchyma(P<0.01).Compared with the pathological staging,the accuracy of CT staging was high.Conclusions:Three phases spiral CT scan can clearly diagnose the clear cell renal carcinoma,which has certain guiding significance in formulating the preoperative scheme.
2016, 41(5): 652-654.
doi: 10.13898/j.cnki.issn.1000-2200.2016.05.033
Abstract:
Objective:To investigate the value of multislice spiral computed tomography angiography(MSCTA) and three-dimensional time of fligt magnetic resornance angiography(3D-TOF MRA) in the diagnosis of intracranial aneurysm.Methods:Fifteen patients with intracranial aneurysm identified by selective digital subtraction angiography(DSA) or aneurysm clipping were examined using MSCTA or 3D-TOF MRA,and the clinical data were retrospectively analyzed.Results:Sixteen aneurysms in 15 patients included 7 aneurysms in ACoA,4 aneurysms in PCoA,2 aneurysms in right internal carotid artery and 3 aneurysms in MCA.Fifteen aneurysms were checked out by MSCTA and 3D-TOF MRA,one aneurysm in the left MCA was missed,the sensitivity of which was 93.75%.MSCTA and 3D-TOF MRA could better display the morphology,size,location and neck of aneurysm,and the relationship between tumor and skull base.Tumor sizes of 13 cases detected by MSCTA or 3D-TOF MRA were coincidence to the results of DSA and operation.Tumor size of 1 case detected by MSCTA and 1 case detected by 3D-TOF MRA were not coincidence to the results of DSA.Tumor morphology of 12 cases detected by MSCTA and 3 cases detected by 3D-TOF MRA were similar to the results of DSA and operation.Conclusions:MSCTA and 3D-TOF MRA can accurately identified the intracranial aneurysm,which can used as a routine metheod in early screening of intracranial aneurysms in high risk population.
Objective:To investigate the value of multislice spiral computed tomography angiography(MSCTA) and three-dimensional time of fligt magnetic resornance angiography(3D-TOF MRA) in the diagnosis of intracranial aneurysm.Methods:Fifteen patients with intracranial aneurysm identified by selective digital subtraction angiography(DSA) or aneurysm clipping were examined using MSCTA or 3D-TOF MRA,and the clinical data were retrospectively analyzed.Results:Sixteen aneurysms in 15 patients included 7 aneurysms in ACoA,4 aneurysms in PCoA,2 aneurysms in right internal carotid artery and 3 aneurysms in MCA.Fifteen aneurysms were checked out by MSCTA and 3D-TOF MRA,one aneurysm in the left MCA was missed,the sensitivity of which was 93.75%.MSCTA and 3D-TOF MRA could better display the morphology,size,location and neck of aneurysm,and the relationship between tumor and skull base.Tumor sizes of 13 cases detected by MSCTA or 3D-TOF MRA were coincidence to the results of DSA and operation.Tumor size of 1 case detected by MSCTA and 1 case detected by 3D-TOF MRA were not coincidence to the results of DSA.Tumor morphology of 12 cases detected by MSCTA and 3 cases detected by 3D-TOF MRA were similar to the results of DSA and operation.Conclusions:MSCTA and 3D-TOF MRA can accurately identified the intracranial aneurysm,which can used as a routine metheod in early screening of intracranial aneurysms in high risk population.
2016, 41(5): 655-658.
doi: 10.13898/j.cnki.issn.1000-2200.2016.05.034
Abstract:
Objective:To evaluate the imaging manifestations and clinical significance of MSCT and MRI in the reversible posterior leukoencephalopathy syndrome(RPLS).Methods:The clinical and imaging data of 15 RPLS patients were retrospectively analyzed.Results:The RPLS lesions located mainly in bilateral posterior subcortical white matter,the manifestation of MRI was the hyperintensities of T2WI and FLAIR.The manifestation of MSCT was the subcortical low density shadow,and the diffusion-weighted images(DWI) in part of lesions were hyperintensities.The lesions of bilateral cerebral hemisphere involved in 15 cases,which included 14 cases(93.3%) in occipital lobe,15 cases(100.0%)in parietal lobe,14 cases(93.3%) in frontal lobe,9 cases(60.0%) in temporal lobe,3 cases(20.0%)in bilateral basal ganglia region and 3 cases(20.0%) in the right side of the basal ganglia region.Three cases(20.0%) in cerebellum,1 case(6.7%) in brain stem and 2 cases(13.3%) in corpus callosum were identified.Among 13 patients detected by DWI,the upper DW1 of 13 cases(100%) were isoheight and high signal.The apparent diffusion coefficient(ADC)mapping of part of lesions in 6 cases were low signal.The abnormal cerebral artery and vein imaging in 3 cases of MR venography and 2 cases of MR artery angiography were not found.Compared with MSCT,the imaging of MRI could clearly show the lesions,and involve more scope,especially in showing the FLAIR sequence.The lesions in 3 cases were significantly improved after treatment,and even disappeared.The softening lesions in the right temporooccipital parietal lobe of 1 case was found because of delayed diagnosis.Conclusions:The prognosis of RPLS is usually benign,and RPLS has the characteristical imaging change,particularly in MRI performance.The imaging characteristics of PRLS should be awared,the early diagnosis and treatment can aviod the permanent neurological sequlae.
Objective:To evaluate the imaging manifestations and clinical significance of MSCT and MRI in the reversible posterior leukoencephalopathy syndrome(RPLS).Methods:The clinical and imaging data of 15 RPLS patients were retrospectively analyzed.Results:The RPLS lesions located mainly in bilateral posterior subcortical white matter,the manifestation of MRI was the hyperintensities of T2WI and FLAIR.The manifestation of MSCT was the subcortical low density shadow,and the diffusion-weighted images(DWI) in part of lesions were hyperintensities.The lesions of bilateral cerebral hemisphere involved in 15 cases,which included 14 cases(93.3%) in occipital lobe,15 cases(100.0%)in parietal lobe,14 cases(93.3%) in frontal lobe,9 cases(60.0%) in temporal lobe,3 cases(20.0%)in bilateral basal ganglia region and 3 cases(20.0%) in the right side of the basal ganglia region.Three cases(20.0%) in cerebellum,1 case(6.7%) in brain stem and 2 cases(13.3%) in corpus callosum were identified.Among 13 patients detected by DWI,the upper DW1 of 13 cases(100%) were isoheight and high signal.The apparent diffusion coefficient(ADC)mapping of part of lesions in 6 cases were low signal.The abnormal cerebral artery and vein imaging in 3 cases of MR venography and 2 cases of MR artery angiography were not found.Compared with MSCT,the imaging of MRI could clearly show the lesions,and involve more scope,especially in showing the FLAIR sequence.The lesions in 3 cases were significantly improved after treatment,and even disappeared.The softening lesions in the right temporooccipital parietal lobe of 1 case was found because of delayed diagnosis.Conclusions:The prognosis of RPLS is usually benign,and RPLS has the characteristical imaging change,particularly in MRI performance.The imaging characteristics of PRLS should be awared,the early diagnosis and treatment can aviod the permanent neurological sequlae.
Analysis of pathogen distribution and drug resistance in 76 cases with Candida bloodstream infection
2016, 41(5): 661-663.
doi: 10.13898/j.cnki.issn.1000-2200.2016.05.036
Abstract:
Objective:To investigate the pathogen distribution and drug resistance of Candida bloodstream infection to provide the basis for clinical rational drug use.Methods:The data of Candida infection isolated from blood culture were retrospectively analyzed in the First Affiliated Hospital of Bengbu Medical College from 2010 to 2014.Results:The 2 237 stains pathogenic bacteria were isolated from 19 245 blood culture specimens,which included 76 strains Candida,and the detection rate was 3.4%.Among the 76 strains Candida,the detect rates of Candida albicans,C.glabrata and C.parapsilosis were 51.3%(39/76),18.4%(14/76) and 15.8% (12/76),respectively,and the patients mainly came from the ICU(14.5%,11/76),and the department of Hematology(11.8%,9/76).The 76 strains Candida were the highest sensitivity to amphotericin B and flucytosine,the sensitive rate of which was 97.4%.The sensitivity rate of 76 strains Candida to voriconazole,fluconazole and itraconazole were 96.1%m,90.8% and 88.2%,respectively.Conclusions:The main pathogen of Candida isolated from bloodstream infection was Candida albicans.The sensitivities of Candida to amphotericin B and flucytosine are the highest,and the sensitive rate of Candida to fluconazole and itraconazole begin to decrease.
Objective:To investigate the pathogen distribution and drug resistance of Candida bloodstream infection to provide the basis for clinical rational drug use.Methods:The data of Candida infection isolated from blood culture were retrospectively analyzed in the First Affiliated Hospital of Bengbu Medical College from 2010 to 2014.Results:The 2 237 stains pathogenic bacteria were isolated from 19 245 blood culture specimens,which included 76 strains Candida,and the detection rate was 3.4%.Among the 76 strains Candida,the detect rates of Candida albicans,C.glabrata and C.parapsilosis were 51.3%(39/76),18.4%(14/76) and 15.8% (12/76),respectively,and the patients mainly came from the ICU(14.5%,11/76),and the department of Hematology(11.8%,9/76).The 76 strains Candida were the highest sensitivity to amphotericin B and flucytosine,the sensitive rate of which was 97.4%.The sensitivity rate of 76 strains Candida to voriconazole,fluconazole and itraconazole were 96.1%m,90.8% and 88.2%,respectively.Conclusions:The main pathogen of Candida isolated from bloodstream infection was Candida albicans.The sensitivities of Candida to amphotericin B and flucytosine are the highest,and the sensitive rate of Candida to fluconazole and itraconazole begin to decrease.
2016, 41(5): 664-665,669.
doi: 10.13898/j.cnki.issn.1000-2200.2016.05.037
Abstract:
Objective:To explore the relationships between homocysteine(Hcy),C reactive protein(CRP) and hypertensive disorder complication pregnancy(HDCP).Methods:One hundred and twenty-six pregnant woman with HDCP(including 69 cases with gestational hypertension,31 cases with mild preeclampsia and 26 cases with severe preeclampsia) and 119 normal late pregnancy women were divided into the HDCP group and control group,respectively.The levels of Hcy and CRP in two groups were detected and compared.Results:The plasma levels of Hcy and CRP in HDCP group were higher than those in control group(P<0.01).The plasma levels of Hcy and CRP in three subgroups were higher than those in the control group(P<0.01).The plasma levels of Hcy and CRP in the 3 subgroups increased gradually with the aggravation of disease(P<0.01).The plasma levels of Hcy and CRP were significantly positively correlated with the degree of HDCP(P <0.01).Conclusions:The plasma levels of Hcy and CRP in HDCP pregnancy women increase with the development of disease,which is the risk factor of HDCP.The plasma levels of Hcy and CRP in HDCP should closely be pay attention to,which can guide the prevention diagnosis and treatment of HDCP.
Objective:To explore the relationships between homocysteine(Hcy),C reactive protein(CRP) and hypertensive disorder complication pregnancy(HDCP).Methods:One hundred and twenty-six pregnant woman with HDCP(including 69 cases with gestational hypertension,31 cases with mild preeclampsia and 26 cases with severe preeclampsia) and 119 normal late pregnancy women were divided into the HDCP group and control group,respectively.The levels of Hcy and CRP in two groups were detected and compared.Results:The plasma levels of Hcy and CRP in HDCP group were higher than those in control group(P<0.01).The plasma levels of Hcy and CRP in three subgroups were higher than those in the control group(P<0.01).The plasma levels of Hcy and CRP in the 3 subgroups increased gradually with the aggravation of disease(P<0.01).The plasma levels of Hcy and CRP were significantly positively correlated with the degree of HDCP(P <0.01).Conclusions:The plasma levels of Hcy and CRP in HDCP pregnancy women increase with the development of disease,which is the risk factor of HDCP.The plasma levels of Hcy and CRP in HDCP should closely be pay attention to,which can guide the prevention diagnosis and treatment of HDCP.
2016, 41(5): 666-669.
doi: 10.13898/j.cnki.issn.1000-2200.2016.05.038
Abstract:
Objective:To detect plasma D-dimer levels in patients with autoimmune diseases (AID) and study the clinical significance.Methods:The levels of plasma D-dimer in 214 patients with AID were detected by latex particle enhanced immunoturbidimetric assay.The AID patients were classified with Classfication Standard of American Rheumatism Association,77 patients with rheumatoid arthritis(RA),69 patients with systemic lupus erythematosus(SLE),35 patients with idiopathic thrombocytopenic purpura,15 patients with systemic sclerosis and 18 patients with primary sjogren's syndrome were selected.The levels of plasma D-dimer were observed during the different activities of these diseases,before and after treatment,the correlations of D-dimer levels with blood routine and biochemical indexes were also analyzed.Results:Plasma D-dimer level in RA patients was significantly higher than that in the other 4 groups (P<0.05 to P<0.01).During the time of the disease with high activity,D-dimer levels in RA and SLE patients were both significantly higher than those of the disease with low activity(P<0.01).After therapy,D-dimer levels in RA and SLE patients were significantly lower than that during and before therapy(P<0.05 to P<0.01).In RA group,the rheumatoid factor was positively correlated with the level of D-dimer(P<0.01).In SLE group,D-dimer level was positively correlated with plasma uric acid level(P<0.01),negatively correlated with the numbers of red blood cell and platelet(P<0.01).Conclusions:In the five common type AID patients,the level of plasma D-dimer in RA patients was highest,following in SLE,and the level of D-dimer was closely associated with disease activity index and treatment phases.The findings suggested plasma D-dimer level may use as a clinical reference index of the disease activity and curative effectiveness in RA and SLE patients.
Objective:To detect plasma D-dimer levels in patients with autoimmune diseases (AID) and study the clinical significance.Methods:The levels of plasma D-dimer in 214 patients with AID were detected by latex particle enhanced immunoturbidimetric assay.The AID patients were classified with Classfication Standard of American Rheumatism Association,77 patients with rheumatoid arthritis(RA),69 patients with systemic lupus erythematosus(SLE),35 patients with idiopathic thrombocytopenic purpura,15 patients with systemic sclerosis and 18 patients with primary sjogren's syndrome were selected.The levels of plasma D-dimer were observed during the different activities of these diseases,before and after treatment,the correlations of D-dimer levels with blood routine and biochemical indexes were also analyzed.Results:Plasma D-dimer level in RA patients was significantly higher than that in the other 4 groups (P<0.05 to P<0.01).During the time of the disease with high activity,D-dimer levels in RA and SLE patients were both significantly higher than those of the disease with low activity(P<0.01).After therapy,D-dimer levels in RA and SLE patients were significantly lower than that during and before therapy(P<0.05 to P<0.01).In RA group,the rheumatoid factor was positively correlated with the level of D-dimer(P<0.01).In SLE group,D-dimer level was positively correlated with plasma uric acid level(P<0.01),negatively correlated with the numbers of red blood cell and platelet(P<0.01).Conclusions:In the five common type AID patients,the level of plasma D-dimer in RA patients was highest,following in SLE,and the level of D-dimer was closely associated with disease activity index and treatment phases.The findings suggested plasma D-dimer level may use as a clinical reference index of the disease activity and curative effectiveness in RA and SLE patients.
2016, 41(5): 670-672.
doi: 10.13898/j.cnki.issn.1000-2200.2016.05.039
Abstract:
Objective:To investigate the status quo of self-management ability and professional commitment in medical students for further analyzing its mutual relationship.Methods:Six hundred 5-year medical students from Bengbu Medical College were investigated using “College student self-management questionnaire” and “College student professional commitment questionnaire”.Results:The scores of self-management ability and professional commitment in medical students were (116.32±14.72) and (85.10±13.24),respectively.Compared with the poor self-management students,the proportion of the well professional commitment in medical students with well self-management was higher(P<0.01).The total score and each factor score of self-management were significantly positive correlation with the total score and each factor score of professional commitment(P<0.01).Regression analysis of career management,interpersonal relationship management,mental and body management and time management were calculated in regression equation as dependent variable of professional commitment(P<0.01).Conclusions:The medical students have good self-management and professional.commitment.Among the self-management,the career management,interpersonal relationship management,mental and body management and time management can affect the professional commitment.The effect of career management is significant,which can explain the 24.1% professional commitment.
Objective:To investigate the status quo of self-management ability and professional commitment in medical students for further analyzing its mutual relationship.Methods:Six hundred 5-year medical students from Bengbu Medical College were investigated using “College student self-management questionnaire” and “College student professional commitment questionnaire”.Results:The scores of self-management ability and professional commitment in medical students were (116.32±14.72) and (85.10±13.24),respectively.Compared with the poor self-management students,the proportion of the well professional commitment in medical students with well self-management was higher(P<0.01).The total score and each factor score of self-management were significantly positive correlation with the total score and each factor score of professional commitment(P<0.01).Regression analysis of career management,interpersonal relationship management,mental and body management and time management were calculated in regression equation as dependent variable of professional commitment(P<0.01).Conclusions:The medical students have good self-management and professional.commitment.Among the self-management,the career management,interpersonal relationship management,mental and body management and time management can affect the professional commitment.The effect of career management is significant,which can explain the 24.1% professional commitment.
2016, 41(5): 676-677,680.
doi: 10.13898/j.cnki.issn.1000-2200.2016.05.041
Abstract:
Objective:To investigate the effects of low frequency pulse therapy combined with acupoint massage on muscle strength and ability of self-care of patients with apoplexy hemiparalysis.Methods:Sixty patients with apoplexy hemiparalysis were randomly divided into the intervention group and control group(30 cases each group).The control group were treated with conventional method,and the intervention group were treated with low frequency pulse therapy combined with acupoint massage based on conventional method.The muscle strength and improvement of ability of self-care between two groups were compared.Results:After treatment,the muscle strength and improvement of ability of self-care in intervention group were significantly better than those in control group(P<0.01).Conclusions:The low frequency pulse therapy combined with acupoint massage can improve the muscle strength and ability of self-care in patients with apoplexy hemiparalysis.
Objective:To investigate the effects of low frequency pulse therapy combined with acupoint massage on muscle strength and ability of self-care of patients with apoplexy hemiparalysis.Methods:Sixty patients with apoplexy hemiparalysis were randomly divided into the intervention group and control group(30 cases each group).The control group were treated with conventional method,and the intervention group were treated with low frequency pulse therapy combined with acupoint massage based on conventional method.The muscle strength and improvement of ability of self-care between two groups were compared.Results:After treatment,the muscle strength and improvement of ability of self-care in intervention group were significantly better than those in control group(P<0.01).Conclusions:The low frequency pulse therapy combined with acupoint massage can improve the muscle strength and ability of self-care in patients with apoplexy hemiparalysis.
Effect of evidence-based oral nursing mode on the periodontal health in the community service worker
2016, 41(5): 678-680.
doi: 10.13898/j.cnki.issn.1000-2200.2016.05.042
Abstract:
Objective:To investigate the intervention effects of the evidence-based oral nursing mode on the periodontal health in community service worker.Methods:The oral health education programme in 60 community service workers with oral diseases was formulated according to the principles of evidence-based nursing.The awareness rate of oral health knowledge and correct rate of health behavior were investigated using the self-design questionnaire before intervention and after 6 months of intervention.The dental plaque indexes were detected before intervention and after 1,3 and 6 months of intervention.Results:The awareness rate of oral health knowledge and correct rate of health behavior after invention were significantly higher than before intervention(P<0.01).The dental plaque indexes after 1,3 and 6 months of intervention were significantly lower than before intervention(P<0.01).Conclusions:The evidence-based oral nursing can effectively improve the awareness rate of oral health knowledge,oral health behavior and reduce the plaque index,which is benefic for the oral and periodontal disease prevention and health care,and worthy of application in clinic.
Objective:To investigate the intervention effects of the evidence-based oral nursing mode on the periodontal health in community service worker.Methods:The oral health education programme in 60 community service workers with oral diseases was formulated according to the principles of evidence-based nursing.The awareness rate of oral health knowledge and correct rate of health behavior were investigated using the self-design questionnaire before intervention and after 6 months of intervention.The dental plaque indexes were detected before intervention and after 1,3 and 6 months of intervention.Results:The awareness rate of oral health knowledge and correct rate of health behavior after invention were significantly higher than before intervention(P<0.01).The dental plaque indexes after 1,3 and 6 months of intervention were significantly lower than before intervention(P<0.01).Conclusions:The evidence-based oral nursing can effectively improve the awareness rate of oral health knowledge,oral health behavior and reduce the plaque index,which is benefic for the oral and periodontal disease prevention and health care,and worthy of application in clinic.
2016, 41(5): 681-683.
doi: 10.13898/j.cnki.issn.1000-2200.2016.05.043
Abstract:
Objective:To investigate the effects of Orem self-care theory in perioperative nursing of patients with lung cancer.Methods:One hundred and thirty perioperative patients with lung cancer were randomly divided into the observation group and control group according to the random number table method(65 cases each group).The control group and observation group were nursed with the conventional method and Orem self-care theory,respectively.The perioperative recovery between two groups were compared.Results:The postoperative expectoration time,ambulation time and hospitalization time in observation group were significantly shorter than those in control group(P<0.01).The differences of the incidence of complication and overall nursing satisfaction between groups were not statistically significant(P >0.05).The percentage rates of the scores of SAS and SDS less than 50 in observation group after 3 and 10 days of operation were higher than those in control group(P<0.05).Conclusions:The application of Orem self-care theory in perioperative patients with lung cancer can facilitate to improve the self-care ability and promote rehabilitation of patients.
Objective:To investigate the effects of Orem self-care theory in perioperative nursing of patients with lung cancer.Methods:One hundred and thirty perioperative patients with lung cancer were randomly divided into the observation group and control group according to the random number table method(65 cases each group).The control group and observation group were nursed with the conventional method and Orem self-care theory,respectively.The perioperative recovery between two groups were compared.Results:The postoperative expectoration time,ambulation time and hospitalization time in observation group were significantly shorter than those in control group(P<0.01).The differences of the incidence of complication and overall nursing satisfaction between groups were not statistically significant(P >0.05).The percentage rates of the scores of SAS and SDS less than 50 in observation group after 3 and 10 days of operation were higher than those in control group(P<0.05).Conclusions:The application of Orem self-care theory in perioperative patients with lung cancer can facilitate to improve the self-care ability and promote rehabilitation of patients.
2016, 41(5): 684-687.
doi: 10.13898/j.cnki.issn.1000-2200.2016.05.044
Abstract:
Objective:To investigate the effects of systematic nursing intervention on the treatment compliance and life quality of patients with diabetic nephropathy.Methods:Eighty-eight patients with diabetic nephropathy were randomly divided into observation group and control group (44 cases in each group).The patients in the control group received routine nursing only,while the observation group received systematic nursing intervention including psychological nursing,dietary guidance,medication guide and exercise guidance in addition to the routine nursing.The mental state,treatment compliance,glycosylated hemoglobin,urinary albumin creatinine ratio,blood pressure and life quality were compared between the two groups.Results:The score of mental state of the observation group was distinctly lower than that of the control group(P <0.01);the score of treatment compliance of the observation group was remarkably higher than that of the control group(P <0.01);the glycosylated hemoglobin,the urinary albumin creatinine ratio and the blood pressure of the of the observation group was significantly lower than that of the control group(P <0.01);the dimension score of life quality was evidently higher than that of the control group(P <0.01).Conclusions:The systematic nursing intervention may effectively improve the mental status,treatment effect and life quality of patients with diabetic nephropathy.
Objective:To investigate the effects of systematic nursing intervention on the treatment compliance and life quality of patients with diabetic nephropathy.Methods:Eighty-eight patients with diabetic nephropathy were randomly divided into observation group and control group (44 cases in each group).The patients in the control group received routine nursing only,while the observation group received systematic nursing intervention including psychological nursing,dietary guidance,medication guide and exercise guidance in addition to the routine nursing.The mental state,treatment compliance,glycosylated hemoglobin,urinary albumin creatinine ratio,blood pressure and life quality were compared between the two groups.Results:The score of mental state of the observation group was distinctly lower than that of the control group(P <0.01);the score of treatment compliance of the observation group was remarkably higher than that of the control group(P <0.01);the glycosylated hemoglobin,the urinary albumin creatinine ratio and the blood pressure of the of the observation group was significantly lower than that of the control group(P <0.01);the dimension score of life quality was evidently higher than that of the control group(P <0.01).Conclusions:The systematic nursing intervention may effectively improve the mental status,treatment effect and life quality of patients with diabetic nephropathy.
Email
RSS